OpenLLM-France/wikimedia huggingface dataset:
# Lumefantrine

Lumefantrine (or benflumetol) is an antimalarial drug. It is only used in combination with artemether. The term "co-artemether" is sometimes used to describe this combination. Lumefantrine has a much longer half-life compared to artemether (3-6 days vs. 2 hours), and is therefore thought to clear any residual parasites that remain after combination treatment.

## Mechanism of action

Exact mechanism by which lumefantrine acts on erythrocytic stages of Plasmodium falciparum is unknown. However, it was shown to exert its action through possible two mechanisms:
* inhibiting β-hematin formation by creating complexes with hemin
* inhibiting nucleic acid and protein synthesis
Moreover, it was shown to interact with human sodium/potassium ATPase subunit α1.

## Metabolism

Lumefantrine is metabolised in the liver by cytochrome P450 3A4 isoenzyme (CYP3A4) and 2D6 (CYP2D6), yielding desbutyl-lumefantrine as a major metabolite.

## Adverse effects

Lumefantrine, as used in combination with artemether, was shown to induce the following side effects:
* prolongation of QT interval, especially in combination with other drugs exhibiting the same effects or in patients with congenital prolongation of the QT interval
* hypersensitivity reactions
* interactions with CYP3A4 and CYP2D6 inducing or inhibiting drugs
* infertility (sperm abnormalities and trouble getting pregnant)
People taking efavirenz as a part of HIV therapy should be wary of potential deviations during treatment, due to a decrease of AUC of this antiretroviral.

## History

Lumefantrine, along with pyronaridine and naphthoquine, were synthesized during the Chinese Project 523 antimalaria drug research effort initiated in 1967; these compounds are all used in combination antimalaria therapies.

## Research

Lumefantrine is being investigated as a part of a regimen with ganaplacide for the treatment of Plasmodium falciparum malaria.
Along with O-choline (octadecyl 2-(trimethylammonio)ethyl phosphate), lumefantrine inhibits in vivo growth of Theileria equi and Babesia caballi, due to inhibition of membrane phospholipid synthesis, hemoglobin digestion and targeting lactate metabolism. Additionally, it can inhibit Babesia gibsoni growth in vitro (synergistically with artemisinin derivatives).
It may exert negative effects on aquatic ecosystems by adversely acting on Chlorella vulgaris, Raphidocelis subcapitata, Lemna minor and Microcystis aeruginosa. Moreover, it is classified as a potential endocrine disrupting compound by decreasing FSHB and increasing prolactin secretion.
Lumefantrine and calcium phosphate-loaded lipid nanoparticles or cubosomes were investigated as a potential treatment of lung cancer due to probable antiangiogenic and anti-inflammatory properties of this combination.
Selene-containing lumefantrine derivatives synthesised through Knoevenagel condensation (which itself is used to synthesise lumefantrine) exhibit potential antibacterial and antifungal activity. Compared with ciprofloxacin, they were shown to more potently bind to E. coli MurB enzyme – an enzyme participating in cell cycle and cell wall synthesis.
# The Greenwood

The Greenwood is a historic apartment building at 425 Greenwood Street in Evanston, Illinois. Built in 1912, the three-story building is set in a neighborhood of single-family houses. Architect Thomas McCall designed the building in the Prairie School style. The building features an overall horizontal emphasis, casement and bay windows, stained glass, and overhanging eaves. Its six apartments have a railroad plan, in which rooms are organized along a narrow central hallway.
The building was added to the National Register of Historic Places on March 15, 1984.
# Outpost (1994 video game)

Outpost is a video game developed and published by Sierra On-Line in 1994. The game was noteworthy for having a hard science fiction approach, with one of the main designers being a former NASA scientist.
Outpost was released for Windows 3.1 and the Macintosh. It was followed by a loosely related sequel, Outpost 2: Divided Destiny.

## Story

A massive asteroid named Vulcan's Hammer is detected to be on a collision course with Earth, and all attempts to divert it from this path have failed. The last attempt, firing a large nuclear warhead at the asteroid, actually ended up splitting it not into five chunks (which would have averted disaster) as humanity hoped, but rather two asteroids. Now, instead of destroying the earth, it will simply wipe out nearly all life on Earth's surface. Extinction is not an option, and so a mission is organized to create a colony on a world elsewhere in the galaxy as the last hope for mankind's survival. The player is in charge of that mission.

## Reception

Initial reviews of Outpost were enthusiastic about the game. The American version of PC Gamer rated the game at 93%, one of its highest ratings ever for the time. It was later made known that the reviewers had in fact played beta versions of the game, and had been promised certain features would be implemented, but never were.
James V. Trunzo reviewed Outpost in White Wolf #49 (Nov., 1994), rating it a 5 out of 5 and stated that "Outpost excels in every way. It plays like a great science fiction novel reads. The graphics, sound and game play are state-of-the-art. I am extremely impressed with the game's depth and variety of approaches to problem solving. The game is also educational without being intrusive. I learned amazing (almost frightening) facts about our space program's capabilities. It was almost like looking into the future."
Indeed, many of the features described in the game's own documentation simply do not exist in the finished game at all. These include the ability to enter diplomatic relations with the rebel colony and the ability to build roads, orbital colonies, or the mass driver. Many of these gameplay aspects were later patched in, though in appearance only, as many of them failed to have any meaningful effect on gameplay.
Following the release of the game, the game's general bugginess and perceived mediocre gameplay, along with the lack of features described in most of the game's reviews and the game's own documentation, led to a minor backlash against the computer game magazines of the time by consumers who bought the game based on their reviews.
In 1996, Computer Gaming World declared Outpost the worst computer game ever released.
# Kings of Comedy Juniors

Kings of Comedy Juniors (Tamil: கிங்ஸ் ஆப் காமெடி ஜூனியர்ஸ்) is a 2017 Indian Tamil-language children's stand-up comedy reality television show that airs on Vijay TV. The first season of the show began airing on 8 April 2017, and ended 17 September 2017 after airing 49 episodes. That aired every Saturday and Sunday on June 24, 2017, The judges are comedy actor Robo Shankar, actress Rambha and Sindhu.
The second season of the show aired from 28 July 2018 to 24 November 2018 every Saturday and Sunday. The judges are actors Robo Shankar and Vani Bhojan, and TV anchor Erode Mahesh.

## Seasons overview

| Season | Season | Episodes | Originally aired | Originally aired | Time |
| Season | Season | Episodes | First aired | Last aired | Time |
| | 1 | 49 | 8 April 2017 (2017-04-08) | 17 September 2017 (2017-09-17) | Saturday and Sunday 19:00 (IST) |
| | 2 | 30 | 28 July 2018 (2018-07-28) | 24 November 2018 (2018-11-24) | Saturday and Sunday 19:00 (IST) |

## Season 1
### Winners

| Winners | Notes | Amount won |
| Sucil | Title Winners | cash prize |
| Uthra | Runner Up | cash prize |
| Athesh | Best Entertainer | cash prize |

#### Finalist

* Mukesh
* Mridhulasree
* Sucil
* Uthra
* Hrithikhasan
* Adhesh

## Cast
### Host

* Priyanka

### Judges

* Robo Shankar
* Rambha
* Sindhu

## Season 2
### Host

* Priyanka Deshpande

### Judges

* Vani Bhojan
* Robo Shankar
* Erode Mahesh

### Winners

| Winners | Notes | Amount won |
| Hema Priya | Title Winners | ₹ 2 Lakhs |
| Santhoshi | Runner Up | ₹ 1 Lakh |
| Keerthana | Best Entertainer | ₹ 1 Lakh |

#### Finalist

* Hemapriya
* Santhoshi
* Monish
* Tharun
* Vishwa
* Keerthana
# Port Blakely, Bainbridge Island, Washington

Port Blakely is a community of Bainbridge Island, Washington in the western United States. It is located on the east side of the island, slightly to the south. The center of Port Blakely is generally defined as the intersection of Blakely Hill Road and Blakely Avenue NE, although the wider area is generally also known as Port Blakely.
The community's name was at one time spelled as Port Blakeley.

## Hall Brothers Shipyard and Port Blakely Mill

Port Blakely was named in 1841 by the Wilkes Expedition for the American naval officer Johnston Blakely.
In 1863, William Renton began operating a sawmill at Port Blakeley. In 1880, brothers Isaac, Winslow and Henry Knox Hall moved their shipyard from Port Ludlow, Washington to a site near the Port Blakely Lumber Mill. At one point, this mill was "the world's largest sawmill under one roof." The lumber mills and shipyard of Port Blakely were adjoined by extensive living quarters and public amenities for mill workers and their families.
"The first true five-masted schooner built on the West Coast was the Inca, built at Port Blakely in 1896." H.K. Hall a 1,237-ton five-masted schooner, was launched here in 1902.
"Between 1881 and 1904, the Hall Brothers launched 77 vessels of every size and rig, including barks, barkentines, three-, four-, and five-masted schooners, steamers, a tug, a government revenue cutter and several yachts. Hall Brothers was largely responsible for building most of the schooners for the Pacific Coast lumber trade."
The shipyard was moved to Winslow in 1903.

## Associated media

Port Blakely was featured in the documentary Port Blakely: Memories of a Mill Town by film maker Lucy Ostrander and her husband Don Sellers.
# The Flames Lie

The Flames Lie (German: Die Flammen lügen) is a 1926 German silent drama film directed by Carl Froelich and starring Hans Adalbert Schlettow, Ruth Weyher and Henny Porten. It was shot at the Staaken Studios in Berlin. The film's sets were designed by Franz Schroedter. It was made by UFA and released under the Parufamet agreement.

## Cast

* Hans Adalbert Schlettow as Konrad Birkinger
* Ruth Weyher as Doritt Lenee, seine Freundin
* Henny Porten as Gertrud von Gehr
* Paul Bildt as Erwin von Gehr, Gertruds Vater
* Gerd Briese as Hermann von Gehr, Gertruds Bruder
* Grete Mosheim as Anne von Berke
* Ferdinand von Alten as Arken, Birkingers Privatsekretär
* Hubert von Meyerinck as Ein Liebhaber
* Lotte Steinhoff
# Sharpbelly

The sharpbelly or wild carp, sharpbelly, or common sawbelly (Hemiculter leucisculus), is a tropical freshwater and brackish water fish belonging to the family Xenocyprididae. It originates in large streams and reservoirs in China, Taiwan, Hong Kong, Korea, and the Amur River basin. It has become established as an exotic species in several other countries, including Iran, Afghanistan, and the former Soviet Union, where it has displaced local species. It was originally described as Culter leucisculus by S. Basilewsky in 1855, and has also been referred to as Chanodichthys leucisculus and Hemiculter leucisculus warpachowskii in scientific literature.
The fish reaches a size up to 23.0 cm (9.1 in) long, and is native to fresh and brackish water habitats with a pH of 7.0, a hardness of 15 DH, and a temperature of 18 to 22 °C (64 to 72 °F). It is green-gray on the back, and white in the belly.
The bulk of its diet includes zooplankton, insects, crustaceans, algae, and detritus. It is of minor commercial importance, primarily in China, where it is canned. In Hong Kong, it is not favored as a table fish because the flesh is unpalatable and very bony.

## Parasites

As most fish species, the sharpbelly harbours several species of parasites. One of them is Paradiplozoon hemiculteri, a monogenean living on the gills. This species is special in that the two hermaphroditic members of the couple are united for life.
# Dallas Harris

Dallas Harris is an American politician from Nevada. A Democrat, Harris was appointed to the 11th district of the Nevada Senate on December 4, 2018, until November 6, 2024.
Prior to her appointment to the legislature, Harris served with the Nevada Public Utilities Commission as an administrative attorney.
Harris is openly gay. She is one of four openly LGBT members of the previous Nevada state legislature, alongside senators David Parks, Pat Spearman and Melanie Scheible.
# Robert Brewer

Robert Brewer may refer to:
* Bobby Brewer (1963-2024), American pastor, author and talk radio personality
* Robert Brewer (figure skater) (born 1939), American figure skater
* Robert Brewer (American football), American football player
* Robert B. Brewer (1924–1996), U.S. Army officer
* Robert S. Brewer Jr. (born 1946), American attorney
# Jacques Lebrun

Jacques Baptiste Lebrun (20 September 1910 – 14 January 1996) was a French sailor. He competed at the 1932, 1936, 1948, 1952 and 1960 Olympics and won a gold medal in the snowbird event in 1932. He missed the 1956 Games for financial reasons.
Lebrun was a boat designer and eventually became technical director of the national sailing association. During World War II he helped to hide a significant part of the Louvre collection from the Germans.
# Motti Ivanir

Motti Ivanir (Hebrew: מוטי איוניר; born March 18, 1964) is a former footballer mostly known for his time in Maccabi Tel Aviv, being the first Israeli to play in the Eredivisie and representing Israel at the national level. Ivanir now works as a manager, is currently managing Hapoel Nof HaGalil at Liga Leumit.

## Playing career
### Club

Ivanir became the first professional Israeli footballer in the Netherlands when he joined Roda JC in 1986.

### International

He made his senior debut for Israel in a January 1986 friendly match against Finland and has earned a total of18 caps, scoring 1 goal. His final international was an April 1992 friendly against Iceland.

## Honours
### As a Player

* Israel State Cup:
** Winner (1): 1988
* Toto Cup:
** Winner (1): 1991–92
* Israeli Premier League:
** Runner-up (1): 1991-92

### As a Manager

* Liga Leumit:
** Runner-up (1): 2003–04
# Mouth for War

"Mouth for War" is a song by American heavy metal band Pantera. It was first released on the band's sixth album Vulgar Display of Power and was the first single off that album. It was later released on the band's compilation album, The Best of Pantera: Far Beyond the Great Southern Cowboys' Vulgar Hits!
The song was released as downloadable content for the music video games Rock Revolution and Rock Band 3, alongside "Walk", "I'm Broken" and "5 Minutes Alone".

## Lyrics and composition

Vocalist Phil Anselmo stated in a 1992 interview on Much More Music, that "Mouth for War" is about channeling your hate into something productive. This is evident in the lyrics "When I channel my hate to productive/I don't find it hard to impress". According to Anselmo, the song was written about the then middleweight champion James Toney.

## Music video

The video shows the band playing the song to an audience. The majority of the video is shot in black and white, and a screenshot of the video was used as the cover for "Walk". It was directed by Paul Rachman who also directed the videos from the band's previous album, Cowboys from Hell, and the feature documentary film American Hardcore.

## Release and reception

"Mouth for War" was the band's first single from their Vulgar Display of Power album. The song is one of Pantera's most popular songs and experienced moderate commercial success, becoming the band's first song to ever chart, reaching number 73 on the UK Singles Chart. It was used as the theme song for MTV's Headbangers Ball.
Metal Hammer ranked the song number 7 on their list of the 50 best Pantera songs.

## Covers

In 1993, iD Software composer Bobby Prince created a MIDI rendition of the song for use in their game Doom.
"Mouth for War" has been covered by Italian melodic death metal band Disarmonia Mundi on their third album, Mind Tricks. Another cover version by Biohazard appears in the Metal Hammer tribute to Dimebag Darrell. An instrumental, all-cello version was recorded by The Portland Cello Project on the Kill Rock Stars label. Avenged Sevenfold covered the song live in 2011, featuring Vinnie Paul on drums.
In March 2021, Lzzy Hale of Halestorm, Reba Meyers of Code Orange, Gina Gleason of Baroness, Madi Watkins of Year of the Knife, Ben Koller of All Pigs Must Die and Mutoid Man, and Jordan Olds (aka Gwarsenio Hall) collectively released a cover of the song on the "Two Minutes to Late Night" YouTube channel.

## Personnel

* Phil Anselmo – vocals
* Dimebag Darrell – guitar
* Rex Brown – bass
* Vinnie Paul – drums

## Charts

| Chart (1992) | Peak position |
| UK Singles (OCC) | 73 |
# Kiss the Pig

Professional ratings :
| Review scores ||
| Source | Rating |
| Allmusic | |
| Chronicles of Chaos | |
| Lambgoat | |
| Last Rites | Positive |
Kiss the Pig is the seventh album by Today Is the Day, released on June 29, 2004 through Relapse Records. Lyrically, the album takes inspiration from the presidency of George W. Bush and the Iraq War. Steve Austin wrote most of the album after a live performance the band played with Slayer in Japan. The same show is where the group met Japanese charcoal artist Takanami Kazuhiko, whose painting titled Evileyes was chosen for the album's cover before recording even began.
The album's title is supposed to be a reference to Austin's critique of capitalism and American society, and was inspired by how "all of us, from the day we are born are taught to love and worship money, even though money is the ruin of mankind."

## Track listing

All tracks are written by Steve Austin

## Accolades

| Year | Publication | Country | Accolade | Rank |
| 2004 | Rock Sound | United Kingdom | "Albums of the Year" | 45 |
| "*" denotes an unordered list. ||||||

## Personnel

Adapted from the Kiss the Pig liner notes.

### Today Is the Day

* Steve Austin – vocals, guitar, sampler, production, engineering
* Chris Debari – bass guitar, backing vocals
* Mike Rosswog – drums

### Production

* Aaron Kotilainen – assistant engineering
* Dave Wilson – assistant engineering

## Release history

| Region | Date | Label | Format | Catalog |
| United States | 2004 | Relapse | CD | RR 6619 |
| United States | 2004 | Rococo | LP | RCC-0004 |
# Pradeep Kumar Majhi

Pradeep Majhi (Odia: ପ୍ରଦୀପ ମାଝି; born 22 February 1976) is an Indian politician. He was a member of parliament in 15th Lok Sabha from Nabarangpur and is at present the State Vice-president of Odisha Pradesh Congress Committee, having held previous offices of State President of Orissa Pradesh Youth Congress, Secretary of the Indian Youth Congress, and President of Zilla Parishad. In 15th Lok Sabha, he asked 1160 questions inside Parliament, the third-highest number questions asked in that Lok Sabha tenure. He asked 501 questions in his first two years, according to The Week magazine. In 2021, Majhi quit from Congress and joined BJD in a Mishran Parba.

## Political career

Majhi is among the rising young leaders of National Congress party. He is very close to Rahul Gandhi, who is Party working-president and also in charge of the Youth Congress affairs. Majhi from Orissa registered history, when he was appointed as the secretary of Indian Youth Congress. This is the first time a person from Orissa has been elevated to this post. While the UPA 2 government is all set to complete two years, prominent "Week' magazine came up with a detailed statistics that Congress MP from Nabarangpur, Mr Majhi has set a new record. The first-timer Lok Sabha MP asked 501 questions in two years with all-time records of 75 percentage of attendance in Parliament irrespective of his additional Orissa Youth Congress responsibilities.

### Orissa Youth Congress president

Orissa Youth Congress had advanced a lot under his leadership and guidance in terms of more discipline, more agitations and movements, infusion of ample fresh bloods in party carder and most significantly propagating Rahul Gandhi's vision and message to youth across the state.

### 2009 Lok Sabha Elections

He was nominated by the Congress party to contest the Lok Sabha elections 2009 from Nabarangpur in Odisha. He won the 2009 Lok Sabha election by a margin of 30830 votes. During his tenure as a parliamentarian among others he played a decisive role in Food Corporation of India procuring maize at MSP from Nabarangpur farmers.
# Tootell House

The Tootell House (also called King's Row or Hedgerow) is a house at 1747 Mooresfield Road in Kingston, Rhode Island that is listed on the National Register of Historic Places.
The two-story, wood-shingled Colonial Revival house on a 3-acre (12,000 m$^2$) tract was designed by Gunther and Bemis Associates of Boston for Fred Tootell. It was built in 1932–1933, while Tootell was married to his first wife Anne Parsons. House design was by John J. G. Gunther. Elizabeth Clark Gunther was the landscape architect for the grounds.
# Mourad Gharbi

Mourad Gharbi (born 21 January 1966) is a Tunisian footballer. He played as a midfielder in 24 matches for the Tunisia national football team from 1987 to 1994. He was also named in Tunisia's squad for the 1994 African Cup of Nations tournament.
# Shivam Bhaje

Shivam Bhaje is a 2024 Indian Telugu-language action drama written and directed by Apsar. It was produced by Maheswara Reddy Mooli, under Ganga Entertainments. It stars Ashwin Babu and Digangana Suryavanshi in the lead roles, alongside Arbaaz Khan, Murali Sharma, Brahmaji, and Tanikella Bharani.

## Cast

* Ashwin Babu as N. Chandra Sekhar "Chandu"
* Digangana Suryavanshi as Sailaja
* Arbaaz Khan as Murali IPS
* Tulasi as Chandu's mother
* Murali Sharma
* Brahmaji
* Tanikella Bharani
* Sai Dheena as Vincent IPS
* Praveen
* Hyper Aadi

## Production
### Filming

The film was officially launched with a Pooja ceremony on November 20, 2023.

### Development

The first look of the film was released on 11 May and teaser was subsequently launched on 19 June.

## Release

Shivam Bhaje was released on 1 August 2024.

## Reception

The Hans India gave the film three stars out of five and said "Shivam Bhaje stands out as a captivating thriller with impressive performances and a distinctive narrative".