OpenLLM-France/wikimedia huggingface dataset:
# MAGEL2

MAGE family member L2 (MAGEL2) is a protein that in human is encoded by the MAGEL2 gene. This protein is a ubuquitin ligase enhancer which is necessary for endsomal protein recycling. This protein is a part of MUST complex (which consists of MAGEL2-USP7-TRIM27 complex).

## Gene

The MAGEL2 gene is located on the long(q) arm of chromosome 15 on position 11.2, from base pair 23,643,549 to base pair 23,647,867. This gene is expressed from the paternal chromosome 15.

## Function

This protein is known to regulate AMPA receptors in hypothalamus. Also it can regualte secretion of hormones such as: oxytocin, arginine vasopressin, somatostatin, TSH, somatotropin, LH. Loss of that protein showed decreased neuoronal activity in hypothalamus and hippocampus of mice via AMPA receptor trafficking defects, consequently neuronal activity gets disrupted and synaptic excitation/inhibition balance is lost.
MAGEL2 is required for balance of serotonin, dopamine and noradrenaline concentrations, in Magel2-null mice concetrations of that neurotransmitters had been decreased.
As mentioned above MAGEL2 participates in MUST complex, which promotes endosomal F-actin polymerization.

## Clinical significance
### Prader-Willi syndrome

Prader-Willi syndrome (PWS) is a rare genetic disorder that is caused by maternal UPD(15) or deletions/epimutations on paternal chromosome 15. PWS can cause variety of symptoms from hypotoniain infancy to behavioural problems in early childhood. Some symptoms can be found in infants aside from hypotonia, are a poor eye coordination, almond-shaped eyes, thin upper lip, also, due to hypotonia, problems with sucking reflex. Their cries are weak and they have difficulty of waking up.
Deletion of MAGEL2 (and other genes that are located on the same region) contributes to symptoms in PWS.

### Schaaf-Yang syndrome

Schaaf-Yang syndrome (SYS) is a rare genetic disorder that is caused by a mutation in a paternally expressed gene MAGEL2. The signs of this disease are: hypotonia, developmental delay and contractures of joints, also another signs of that disease are unique facial features, small hands, problems with eye and short stature.
As mentioned above, SYS is caused by LoF variants of the paternal copy of MAGEL2.
# Ernst Mahle

Ernst Mahle (born 3 January 1929) is a Brazilian composer and orchestra conductor of German birth.

## Biography

Mahle was born in Stuttgart, Germany. He studied music with Johann Nepomuk David in Stuttgart before coming to Brazil in 1951, and then with Hans-Joachim Koellreutter in Piracicaba. He became a Brazilian citizen in 1962. In 1953 he was one of the founders of the Escola de Música de Piracicaba. After teaching music there, he became artistic director and conductor of the orchestra and choir of the institute, holding these posts for more than fifty years.
In 2005, Mahle composed the opera O Garatuja, libretto by Eugênio Leandro. The opera was based on the homonymous novel by José de Alencar, which was premiered on 27 April 2006, at the Teatro Municipal de Piracicaba "Dr Losso Netto". He is a member of the Brazilian Academy of Music (chair no. 6).

## Works

* Marroquinhas Fru-Fru (1974) opera, libretto by Maria Clara Machado
* A Moreninha (1979) opera, libretto by José Maria Ferreira
* O Garatuja (2006) opera, libretto by Eugênio Leandro
* Isaura (2023) opera <https://abmusica.org.br/noticias/ernst-mahle-compoe-a-opera-isaura-com-estreia-prevista-para-2023/>
# Julius E. Haycraft

Julius Everett Haycraft (August 26, 1871 – November 5, 1951) was an American lawyer and politician.

## Biography

Haycraft was born on a farm in Blue Earth County, Minnesota, near the city of Madelia, on August 26, 1871. He went to the Minnesota public schools, and to Curtiss Business College in Minneapolis. Haycraft read law in a Madelia law office and was admitted to the Minnesota bar in 1896.
He lived in Madelia with his wife and family and served as the city's postmaster. A Republican, Haycraft served in the Minnesota Senate from 1911 to 1914. In 1915, he moved to Fairmont with his wife and family. Haycraft served as the president of the Martin County Historical Society. He served as a Minnesota District Court judge from 1925 to 1948. Haycraft's nickname was "The Sturdy Little Yankee from Watonwan County."
He died at his home in Fairmont on November 5, 1951.
# Bundesstraße 200

The Bundesstraße 200 is a German federal road or Bundesstraße and the northeast–southwest link between Flensburg, Wanderup and Husum in the northern part of the state of Schleswig-Holstein.

## Route

The B 200 begins at the German-Danish border north of Flensburg. It then bypasses the city of Flensburg where it meets the B 199. It then reuns south west where it meets the A 7 motorway. The route continues until it meets the Husum bypass of the B 5.

## Major junctions

{{DEUint|exit|name
| State | District | Location | km | mi | Exit | Name | Destinations | Notes |
| state=Schleswig-Holstein | sspan=14 | district=Schleswig-Flensburg | dspan=3 | location=Harrislee | lspan=3 | km= | exit= | name=[[Kupfermühlebbxxhh]/Kruså former border crossing | type=trans | road= Sekundærrute 170 – Aabenraa, Kolding | notes=Border crossing is no longer operational since 2001 Northern endpoint of dual carriageway Trucks prohibited }} |
| | | | Wassersleben | Wassersleben | incomplete junction: no entry ramp: Wassersleben → Flensburg |
| | | Rest area | Wassersleben | Wassersleben rest area | |
| Flensburg | Nordstadt | | | | Klues | Flensburg-Klues | |
| Flensburg | Westliche Höhe | | | | Duburg | Dänemark (Trucks), Pattburg, Harrislee, Flensburg-Duburg | Dänemark is only signed northbound |
| Flensburg | Friesischer Berg | | | | Flensburg-Zentrum | B 199 – Dänemark (Trucks), Niebüll, Flensburg-Zentrum | Northern Endpoint of concurrency with the B 199 Dänemark is only signed northbound |
| Flensburg | Weiche/Südstadt | | | | Rude | Flensburg-Rude | |
| Flensburg | Weiche/Südstadt | | | | Flensburg-Süd | B 199 – Kappeln, Glücksburg, Sörup, Satrup, Flensburg Süd/Ost | Southern Endpoint of concurrency with the B 199 Sörup, Satrup and Flensburg Ost are only signed northbound |
| Schleswig-Flensburg | Handewitt | | | | Jarplund-Weding | Kiel, Schleswig, Flensburg-Weiche, Jarplund-Weding | Kiel is only signed southbound |
| Schleswig-Flensburg | Handewitt | | | 3 | Flensburg | A 7 / E45 – Hamburg, Kiel, Kolding, Bundesgrenze | Bundesgrenze is only signed northbound |
| No junctions along Wanderup, Haselund and Viöl ||||||||
| Nordfriesland | Husum | | | | Husum-Messe | B 5 – Hamburg, Schleswig, Niebüll, ( A 23) | |
| Nordfriesland | Husum | | | | Husum-Schleswiger Chaussee | B 201 – Schleswig | Former route in Husum cross-level intersection |
| Nordfriesland | Husum | | | | Husum-Kuhsteig | B 5 – Hamburg, Niebüll | Former route in Husum cross-level intersection |
| 1.000 mi = 1.609 km; 1.000 km = 0.621 mi Concurrency terminus Closed/former Incomplete access Route transition |||||||||
# Superman: True Brit

Superman: True Brit is a DC Comics Elseworlds first published in 2004 in the US, and by Titan Books in the UK. Written by John Cleese and Kim Howard Johnson, with art by John Byrne and Mark Farmer, it reimagines the origin of Superman, by considering how Clark Kent's upbringing would be different if his spaceship had crashed in Weston-super-Mare in England instead of the fictional town of Smallville in Kansas, America.
The story aims to poke fun at the apparent desire to conform embedded in the British psyche, as well as mocking the British tabloid press, in particular the Daily Star. Characters with similarities to Superman regulars Lois Lane, Jimmy Olsen and Perry White make an appearance.

## Plot

Kal-El, instead of landing in Kansas, is intentionally sent to England (as it is the heart of the British Empire). He is found by the Clarks, who view a headset video found with Kal-El, learning of his origins. They mistake "Kal-El" for "Colin" and name him Colin Clark. Being raised stereotypically British includes belief in the philosophy: "What would the neighbours think?"
When Colin's powers begin to surface, each power causes a unique problem: when he learns to fly, he smashes the ceiling, and when he acquires heat vision, he accidentally burns his mother, though his father creates glasses (from the glass of his spaceship) to help contain the heat. Eventually Colin agrees not to use his powers, as they are causing problems.
Colin goes to university and meets and falls in love with Louisa Layne-Ferret, who initially ignores him completely. After a tragic cricket accident in which the bowler is impaled by Colin's cricket bat, a guilty Colin meets Peregrine Whyte-Badger, who takes both Colin and Louisa under his wing to become reporters for the British tabloid Daily Smear.
Although his parents hated it when he used any of his powers, after heroically saving the Rutles, Colin adopts a secret identity and garish costume and becomes Superman.

## Reception

The book had a mixed reception from British critics, some of whom felt that the jokes and stereotypes used in the book were tired and no longer valid.
# Self Destruction Blues

Professional ratings :
| Review scores ||
| Source | Rating |
| AllMusic | |
Self Destruction Blues is the third album by the Finnish rock band Hanoi Rocks, released in 1982. Although often listed as a studio album, Self Destruction Blues is a compilation of singles and B-sides that the band recorded in 1981 and 1982. None of the tracks on Self Destruction Blues, however, appear on their previous albums. Guns N' Roses were rumoured to have recorded a cover version of "Beer and a Cigarette" for their 1993 release "The Spaghetti Incident?". Of note is the fact that although Gyp Casino plays on the LP, his replacement Razzle actually appears on the cover.
"Dead by X-Mas" has been covered by the Japanese hardcore band The Piass in 1994, and the British electro group Sohodolls in 2007.

## Personnel
### Hanoi Rocks

* Michael Monroe – vocals, saxophone, drums on track 15
* Andy McCoy – guitars
* Nasty Suicide – guitars
* Sam Yaffa – bass
* Gyp Casino – drums on tracks 1, 3, 4 and 6–14

### Additional musicians

* Razzle – vocals on track 15
* Keimo Hirvonen – drums on track 2 and 5

## Charts

| Chart (1982) | Peak position |
| Finnish Albums (The Official Finnish Charts) | 28 |
# Saint Peter Island (Bulgaria)

St. Peter Island (Bulgarian: остров св. Петър, ostrov sv. Petar) is a Bulgarian island in the Black Sea, with an area of 0.025 square kilometres (0.010 square miles) and a height of 9 metres (30 feet) above sea level. Also known as Bird Island, it is located in the Bay of Sozopol, close to the St. Ivan and St. Cyricus Islands. As it was not mentioned in any sources until the mid-19th century, it is presumed to have separated from the larger St. Ivan Island (which is a few hundred meters to the west) as a consequence of some kind of natural phenomenon around that time. Archaeologists have discovered the ruins of a Bulgarian National Revival-time chapel, as well as traces of ancient pottery. Two small islets or large rocks also existed to the east of St. Peter, known by the names of Milos and Gata; they were last described by Russian war correspondents in the 1820s and have presumably submerged in the following years.
# Ekaterina Avvakumova

Yekaterina Sergeyevna Avvakumova (Russian: Екатерина Сергеевна Аввакумова, Korean: 예카테리나 세르게예브나 아바쿠모바, romanized: Yekʰat'erina Sŭrŭgeyebŭna Abakʰumoba, born 26 October 1990) is a Russian-born South Korean biathlete. She obtained Korean citizenship in 2017. She competed in the 2018 Winter Olympics and in the 2025 Asian Winter Games. In the 2025 Asian Winter Games she won South Korea’s first gold medal in biathlon at any Asian Winter Games.

## Career results
### Olympic Games

0 medals
| Event | Individual | Sprint | Pursuit | Mass start | Relay | Mixed relay |
| 2018 Pyeongchang | 16th | 87th | — | — | 18th | — |
| 2022 Beijing | 73rd | 49th | LAP | — | — | — |

### World Championships

0 medals
| Event | Individual | Sprint | Pursuit | Mass start | Relay | Mixed relay | Single mixed relay |
| 2017 Hochfilzen | 5th | 63rd | — | 30th | 18th | 19th | — |
| 2021 Pokljuka | 28th | 67th | — | — | 23rd | 26th | 23rd |
| 2023 Oberhof | 48th | 30th | 53rd | — | — | 21st | 25th |
| 2024 Nové Město na Moravě | 31st | 42nd | 44th | — | 19th | 25th | 15th |
# William R. Griffith House

The William R. Griffith House, also known as the Cathedral House or the Cathedral House of St. Stephen's Episcopal Cathedral, is an historic, American home that is located in Harrisburg, Dauphin County, Pennsylvania.
It was added to the National Register of Historic Places in 1976.

## History and architectural features

Built between 1840 and 1843, this historic structure is a three-story, three-bay-wide, brick dwelling that was designed in the Greek Revival style. The front block measures twenty-eight feet by forty feet, with a narrower rear block measuring fifteen feet by fifty feet. It features a front portico with freestanding Ionic order columns.
It was added to the National Register of Historic Places in 1976.
# Rudzienko-Kolonia

Rudzienko-Kolonia is a village in the administrative district of Gmina Michów, within Lubartów County, Lublin Voivodeship, in eastern Poland.
# Josef Schwarz

Josef "Sepp" Schwarz (born 20 May 1941 in Strabowitz, Sudetenland, 9.Germany; today Třebovice, Czech Republic) is a retired German long jumper. He represented West Germany at the 1972 Summer Olympics in Munich. Schwarz set the world's best year performance in the men's long jump in the year 1970: 8.35 metres (personal best); this also was the world record at low altitude, until 1975. He also had winning performances in 1970 at the European Cup in Sarajevo and the West German Championships.
# Laura Barrett

Laura Alexandra Barrett is a Canadian indie pop singer-songwriter, best known for incorporating the kalimba into her music. In addition to her solo work, Barrett has also performed as a member of The Hidden Cameras, Henri Fabergé and the Adorables, Woodhands and Sheezer.
Barrett was born in Toronto. She studied English literature and linguistics at the University of Toronto, graduating in 2006. She later returned to school to complete a master of education and works as an occasional teacher within the Toronto District School Board.
A classically trained pianist, Barrett began studying piano at 8 years of age. She took up the kalimba as a hobby after buying one on eBay. Her first public performance as a solo performer was a cover of "Smells Like Nirvana" at a "Weird Al" Yankovic tribute concert (She had previously been a part of the band Lake Holiday). She subsequently released two EPs, and was the musical director for a New York City production of Maggie MacDonald's play The Rat King.
Barrett released her first full-length album, Victory Garden, in 2008 on Paper Bag Records. Produced by Paul Aucoin, the album featured Basia Bulat, Ajay Mehra and Lief Mosbaugh. In December 2008 Laura Barrett was the recipient of a CBC Radio 3 Bucky Award for "Sexiest Musician".
Barrett took part in the interactive documentary series City Sonic in 2009. The series, which featured 20 Toronto artists, had her talk about her first concert. The first rock concert she attended was, at the age of 12, at the Art Gallery of Ontario for the Rheostatics experimental set Music Inspired by the Group of Seven. Between 2010 and 2015 Barrett performed in Sheezer, an all-female Weezer tribute band]], along with Robin Hatch, Dana Snell and Alysha Haugen. Started as a joke, the band covered music from the Weezer's first two albums The Blue Album and Pinkerton.
In 2010, Barrett accompanied The Magnetic Fields on their 11-date North American "Realism" tour. The following year she participated in the National Parks Project, collaborating with musicians Cadence Weapon and Mark Hamilton and filmmaker Peter Lynch to produce and score a short film about Alberta's Waterton Lakes National Park.
Who Is the Baker?, Barrett's first album in eleven years, was released in 2019. Recorded by Don Kerr, the album featured Karen Ng and Dana Snell. During the years prior to the release, Barrett mentioned musicians as part of Girls Rock Camp Toronto and composed scores alongside José Contreras for the films Porch Stories (2015) and Birdland (2018).

## Discography

* Who is the Baker? (2019)
* Victory Garden (2009)
* Earth Sciences (2008)
# Michalis Charalampous

Michalis Charalampous (Greek: Μιχάλης Χαραλάμπους; born 29 January 1999) is a Cypriot professional footballer who plays as a forward for Enosis Neon Paralimni.

## Career
### Ethnikos Achna

Charalampous made his Cypriot First Division debut at the age of 15, starting the match and playing for 45 minutes in Ethnikos Achna's 5–0 victory against AEK Kouklia on 18 May 2014.

### APOEL

On 2 February 2015, at the age 16, he moved to Cypriot First Division champions APOEL. He made his official debut on 7 May 2016, coming on as a 71st-minute substitute in APOEL's 1–0 away defeat against Apollon Limassol at the end of the 2015–16 season.

## Honours

APOEL
* Cypriot First Division: 2015–16, 2016–17
# Saharanpur Junction railway station

Saharanpur Junction railway station is a junction railway station on the Northern Railway network in the state of Uttar Pradesh, India. Its station code is SRE. The railway station is also set to be redeveloped, as announced by Railway Minister Ashwini Vaishnaw.

## Gallery

* Outside view of Saharanpur Junction
* Saharanpur Junction platform board
* Saharanpur platform board
* Saharanpur railway platform
* Saharanpur Junction
* Saharanpur Junction platform 4.

## Electric Loco Shed, Khanalampura

Electric Loco Shed Khanalampura (ELS KJGY) is situated in Saharanpur, Uttar Pradesh, India. It is among the newest electric loco sheds of Indian Railways. The shed was Commissioned in 2015.
| SN | Locomotives | HP | Quantity |
| 1. | WAG-7 | 5350 | 16 |
| 2. | WAG-9 | 6120 | 135 |
| Total Locomotives Active as of February 2025 | Total Locomotives Active as of February 2025 | Total Locomotives Active as of February 2025 | 151 |
# Carlo Chenis

Carlo Chenis (20 April 1954 – 19 March 2010) was an Italian Catholic bishop. He was ordained a priest in the Salesian Society and later became the Bishop of Civitavecchia–Tarquinia.

## Early life and career

Carlo was born in Turin, Italy on 20 April 1954 and completed his studies in philosophy and theology at the Pontifical Salesian University. On 26 May 1984, he was ordained a priest in Cuorgne for the Salesians of Don Bosco, and later obtained an academic degree in materials science with a specialization in literary arts at the University of Turin in 1989. He held numerous positions in the administrative academic when he became a professor of theoretical philosophy at the Pontifical Salesian University. He became a coordinator of the Secretariat of Student Relations and chaplain of the university, from 1986 to 1998. During his job as a coordinator, he was appointed secretary of the Pontifical Commission for the Cultural Heritage of the Church in 1995.

## Personal life

On 21 December 2006, Chenis was elected bishop of Civitavecchia–Tarquinia and later received his episcopal consecration in the Basilica of St. John Bosco in Rome from the Secretary of State Cardinal, Tarcisio Bertone, on 10 February 2007. On 24 February, he took possession of the diocese, overseeing the port of Civitavecchia, a church within the Trajan markets.

## Death

Chenis died on 19 March 2010, at the age of 55.
# Choreutis parva

Choreutis parva is a moth in the family Choreutidae. It was described by Pagenstecher in 1884. It is found on the Moluccas.
# Miljačići

Miljačići (Cyrillic: Миљачићи) is a village in the municipality of Kakanj, Bosnia and Herzegovina.

## Demographics

According to the 2013 census, its population was 64.
Ethnicity in 2013 :
| Ethnicity | Number | Percentage |
| Bosniaks | 31 | 48.4% |
| Croats | 29 | 45.3% |
| other/undeclared | 4 | 6.3% |
| Total | 64 | 100% |
# George Eisman

George Eisman (August 5, 1950 – April 23, 2017) was an American registered dietitian and veganism activist. He was the co-founder of the Academy of Nutrition and Dietetics Vegetarian Nutrition Practice Group. In 1993, he was inducted into the Vegan Hall of Fame.

## Early life and education

Eisman was born in Miami. He was educated at Middlebury College and obtained a bachelor's degree from Florida State University. In 1975, he obtained a master's degree in geography from the University of Toronto and a master's degree in nutrition from Florida International University in 1976.

## Career

Eisman was one of seven reviewers for the 1988 position of the American Dietetic Association on vegetarian diets. He taught vegan nutrition at Miami Dade College. He is credited with establishing the first accredited program on vegan studies in the United States. The course influenced T. Colin Campbell. His lectures were published in 1993.
He co-founded the Academy of Nutrition and Dietetics Vegetarian Nutrition Practice Group. In 1994, he authored the The Most Noble Diet and A Guide to Vegan Nutrition in 2015. He was a regular speaker at the North American Vegetarian Society's Summerfest. He was nutrition director of the Coalition for Cancer Prevention Through Plant-Based Eating.

## Death

Eisman died from cancer at Watkins Glen, New York in 2017, aged 66.

## Selected publications

* Basic Course in Vegetarian and Vegan Nutrition (1993)
* The Most Noble Diet: Food Selection and Ethics (1994)
* Don't Let Your Diet Add to Your Cancer Risk (2008)
* A Guide to Vegan Nutrition (2015)
# William R. Jones House

The William R. Jones House is an historic house at 307 Harvard Street in Cambridge, Massachusetts. It is a 2+1⁄2-story wood-frame house, whose Second Empire styling includes a flared mansard roof and flushboarded siding scored to resemble ashlar stone. It has a rare example in Cambridge of a curvilinear front gable, in which is an oculus window. Its windows are topped by heavy decorative hoods, and the porch features square posts with large decorative brackets. The house was built c. 1865 for William R. Jones, a soap manufacturer, and typifies the houses that were built lining Harvard Street in the 19th century after the Dana estate was subdivided.
The house was listed on the National Register of Historic Places in 1983.
# Spatharë

Spatharë is a village in the former municipality of Vendreshë in Berat County, Albania. At the 2015 local government reform it became part of the municipality Skrapar.
# Judith Moffett

Judith Moffett (born 1942) is an American author and academic. She has published poetry, non-fiction, science fiction, and translations of Swedish literature. She has been awarded grants and fellowships from the National Endowment for the Arts and the National Endowment for the Humanities and presented a paper on the translation of poetry at a 1998 Nobel Symposium.
She began her career writing poetry and about poets, including a 1984 book about James Merrill, who was both her friend and mentor. Moffett still writes for organizations such as the Academy of American Poets. She did not publish science fiction until 1986, but gained almost immediate attention by winning the first Theodore Sturgeon Award in 1987. Her first novel, Pennterra (1987), further enhanced her reputation. It is noted both for its treatment of alien sexuality and as an example of Quakers in science fiction. In the following year, 1988, she won the John W. Campbell Award for Best New Writer in Science Fiction. In 1989 her novella Tiny Tango also received award nominations.