# List of National Historic Landmarks in South Carolina

This is a List of National Historic Landmarks in South Carolina, United States. The United States' National Historic Landmark (NHL) program is operated under the auspices of the National Park Service, and recognizes buildings, sites, structures, districts, and objects according to a list of criteria of national significance. There are 76 NHLs in South Carolina and 3 additional National Park Service-administered areas of primarily historic importance.
Architects whose work is recognized by two or more separate NHLs in the state are:
* Robert Mills (8 sites),
* Edward Brickell White (4 sites),
* Gabriel Manigault (3 sites), and
* William Wallace Anderson (2 sites).
These tallies do not include any buildings that are contributing properties within historic districts unless they are also individually designated as NHLs.
There are five places listed for their association with artists and writers.
There are four World War II-era museum ships; all are located at Patriot's Point in Charleston Harbor.

## Current NHLs in South Carolina

Download coordinates as:
* KML
* GPX (all coordinates)
* GPX (primary coordinates)
* GPX (secondary coordinates)
The 76 NHLs in South Carolina are distributed across 16 of the 46 counties in the state; 42 of the 76 are located in Charleston County.
| | Landmark name | Image | Date designated | Location | County | Description |
| 1 | William Aiken House and Associated Railroad Structures | William Aiken House and Associated Railroad Structures More images | November 4, 1963 (#66000698) | Charleston 32°47′21″N 79°56′15″W﻿ / ﻿32.789167°N 79.9375°W﻿ / 32.789167; -79.9375﻿ (William Aiken House and Associated Railroad Structures) | Charleston | Structures of South Carolina Canal and Railroad Company, the longest operating railroad in the world in 1833, and home of founder William Aiken |
| 2 | Atalaya and Brookgreen Gardens | Atalaya and Brookgreen Gardens More images | October 5, 1992 (#84002045) | Murrells Inlet 33°30′50″N 79°05′07″W﻿ / ﻿33.513889°N 79.085278°W﻿ / 33.513889; -79.085278﻿ (Atalaya and Brookgreen Gardens) | Georgetown | Landmark combining Atalaya and portions of Brookgreen Gardens associated with artist Anna Hyatt Huntington |
| 3 | Beaufort Historic District | Beaufort Historic District More images | November 7, 1973 (#69000159) | Beaufort 32°26′08″N 80°40′04″W﻿ / ﻿32.435556°N 80.667778°W﻿ / 32.435556; -80.667778﻿ (Beaufort Historic District) | Beaufort | |
| 4 | Bethesda Presbyterian Church | Bethesda Presbyterian Church More images | February 4, 1985 (#85003258) | Camden 34°14′48″N 80°36′19″W﻿ / ﻿34.246589°N 80.605213°W﻿ / 34.246589; -80.605213﻿ (Bethesda Presbyterian Church) | Kershaw | Church designed by Robert Mills |
| 5 | William Blacklock House | William Blacklock House More images | November 7, 1973 (#73001681) | Charleston 32°46′59″N 79°56′22″W﻿ / ﻿32.782927°N 79.939353°W﻿ / 32.782927; -79.939353﻿ (William Blacklock House) | Charleston | Adamesque house, possibly designed by Gabriel Manigault |
| 6 | Borough House | Borough House More images | June 7, 1988 (#72001224) | Stateburg 33°57′14″N 80°32′16″W﻿ / ﻿33.953889°N 80.537778°W﻿ / 33.953889; -80.537778﻿ (Borough House) | Sumter | "The oldest and largest collection of 'high style' pise de terre (rammed earth) buildings in the United States". Across the road from Church of the Holy Cross |
| 7 | Miles Brewton House | Miles Brewton House More images | October 9, 1960 (#66000699) | Charleston 32°46′20″N 79°55′56″W﻿ / ﻿32.772131°N 79.932201°W﻿ / 32.772131; -79.932201﻿ (Miles Brewton House) | Charleston | Fine examples of a "double house" (having four main rooms per floor) in Charleston |
| 8 | Robert Brewton House | Robert Brewton House More images | October 9, 1960 (#66000700) | Charleston 32°46′28″N 79°55′45″W﻿ / ﻿32.774388°N 79.929041°W﻿ / 32.774388; -79.929041﻿ (Robert Brewton House) | Charleston | Charleston's oldest dated "single" house (one room wide, with the narrow end toward the street, and entry centered in long side) |
| 9 | Brick House Ruins | Brick House Ruins More images | April 15, 1970 (#70000580) | Edisto Island 32°35′59″N 80°19′32″W﻿ / ﻿32.599774°N 80.325420°W﻿ / 32.599774; -80.325420﻿ (Brick House Ruins) | Charleston | Ruins of a plantation house that burned in 1929 |
| 10 | Burt-Stark Mansion | Burt-Stark Mansion More images | October 5, 1992 (#70000559) | Abbeville 34°10′49″N 82°22′55″W﻿ / ﻿34.180317°N 82.382023°W﻿ / 34.180317; -82.382023﻿ (Burt-Stark Mansion) | Abbeville | Where the American Civil War ended. |
| 11 | Camden Battlefield | Camden Battlefield | January 20, 1961 (#66000707) | Camden 34°20′47″N 80°36′27″W﻿ / ﻿34.346389°N 80.6075°W﻿ / 34.346389; -80.6075﻿ (Camden Battlefield) | Kershaw | Site of Battle of Camden, British victory in 1780 |
| 12 | Chapelle Administration Building | Chapelle Administration Building More images | December 8, 1976 (#76001710) | Columbia 34°00′37″N 81°01′15″W﻿ / ﻿34.010263°N 81.020966°W﻿ / 34.010263; -81.020966﻿ (Chapelle Administration Building) | Richland | Allen University building designed by John A. Lankford, "dean of black architecture" |
| 13 | Charlesfort-Santa Elena Site | Charlesfort-Santa Elena Site More images | January 3, 2001 (#74001822) | Parris Island 32°18′23″N 80°40′32″W﻿ / ﻿32.306389°N 80.675556°W﻿ / 32.306389; -80.675556﻿ (Charlesfort-Santa Elena Site) | Beaufort | Archeological site of French fort built in 1562 and Spanish forts built in 1566 and after. |
| 14 | Charleston Cigar Factory | Charleston Cigar Factory More images | December 13, 2024 (#100011360) | 701 East Bay St. 32°47′52″N 79°56′05″W﻿ / ﻿32.7978°N 79.9347°W﻿ / 32.7978; -79.9347﻿ (Charleston Cigar Factory) | Charleston | |
| 15 | Charleston Historic District | Charleston Historic District More images | October 9, 1960 (#78002497) | Charleston 32°47′08″N 79°56′13″W﻿ / ﻿32.785556°N 79.936944°W﻿ / 32.785556; -79.936944﻿ (Charleston Historic District) | Charleston | Historic district including 81 contributing properties and 700 others. |
| 16 | Church of the Holy Cross | Church of the Holy Cross More images | November 7, 1973 (#73001732) | Stateburg 33°57′39″N 80°31′55″W﻿ / ﻿33.960744°N 80.531944°W﻿ / 33.960744; -80.531944﻿ (Church of the Holy Cross) | Sumter | Gothic Revival Church constructed of rammed earth in 1852. Across the road from Borough House |
| 17 | Coker Experimental Farms | Coker Experimental Farms | July 19, 1964 (#66000706) | Hartsville 34°21′47″N 80°03′35″W﻿ / ﻿34.363056°N 80.059722°W﻿ / 34.363056; -80.059722﻿ (Coker Experimental Farms) | Darlington | Site of crop-improvement experiments that "played a great role in the agricultural revolution of the South" |
| 18 | College of Charleston | College of Charleston More images | November 11, 1971 (#71000748) | Charleston 32°47′03″N 79°56′17″W﻿ / ﻿32.784167°N 79.938056°W﻿ / 32.784167; -79.938056﻿ (College of Charleston) | Charleston | Historic and attractive campus center; Randolph Hall, Towell Library, and Gate Lodge completed by 1856, designed by William Strickland, Edward Brickell White, and George E. Walker |
| 19 | Drayton Hall | Drayton Hall More images | October 9, 1960 (#66000701) | Charleston 32°52′15″N 80°04′35″W﻿ / ﻿32.8709°N 80.0763°W﻿ / 32.8709; -80.0763﻿ (Drayton Hall) | Charleston | Plantation house built in 1742 of Palladian architectural style |
| 20 | Exchange and Provost | Exchange and Provost More images | November 7, 1973 (#69000160) | Charleston 32°46′37″N 79°55′37″W﻿ / ﻿32.776842°N 79.927009°W﻿ / 32.776842; -79.927009﻿ (Exchange and Provost) | Charleston | Variously a customhouse, mercantile exchange, military prison and barracks, post office, and meeting place of the 1790 State Legislature |
| 21 | Farmers' and Exchange Bank | Farmers' and Exchange Bank More images | November 7, 1973 (#73001685) | Charleston 32°46′39″N 79°55′37″W﻿ / ﻿32.777435°N 79.926964°W﻿ / 32.777435; -79.926964﻿ (Farmers' and Exchange Bank) | Charleston | A unique Moorish-style bank building built in 1854 |
| 22 | Fig Island | Upload image | March 29, 2007 (#70000585) | Charleston 32°34′13″N 80°12′55″W﻿ / ﻿32.5703°N 80.2153°W﻿ / 32.5703; -80.2153﻿ (Fig Island) | Charleston | Archaeological site that is "one of the most complex shell-ring sites" in the United States |
| 23 | Fireproof Building | Fireproof Building More images | November 7, 1969 (#69000161) | Charleston 32°46′37″N 79°55′52″W﻿ / ﻿32.776923°N 79.931052°W﻿ / 32.776923; -79.931052﻿ (Fireproof Building) | Charleston | Designed by Robert Mills to be the most fireproof building in America; now the South Carolina Historical Society building. |
| 24 | First Baptist Church | First Baptist Church More images | November 7, 1973 (#71000800) | Columbia 34°00′21″N 81°02′00″W﻿ / ﻿34.005864°N 81.033450°W﻿ / 34.005864; -81.033450﻿ (First Baptist Church) | Richland | Where the American Civil War started, with the secession of South Carolina from the Union. |
| 25 | Fort Hill (John C. Calhoun House) | Fort Hill (John C. Calhoun House) More images | December 19, 1960 (#66000708) | Clemson 34°40′34″N 82°50′21″W﻿ / ﻿34.675976°N 82.839208°W﻿ / 34.675976; -82.839208﻿ (Fort Hill (John C. Calhoun House)) | Pickens | Home of John C. Calhoun, now within Clemson University campus. |
| 26 | William Gibbes House | William Gibbes House More images | April 15, 1970 (#70000575) | Charleston 32°46′15″N 79°56′04″W﻿ / ﻿32.770701°N 79.934493°W﻿ / 32.770701; -79.934493﻿ (William Gibbes House) | Charleston | Adamesque style home with a beautiful ballroom, and exceptional wrought iron work and marble steps in front |
| 27 | Graniteville Historic District | Graniteville Historic District More images | June 2, 1978 (#78002491) | Graniteville 33°34′01″N 81°48′30″W﻿ / ﻿33.566893°N 81.808377°W﻿ / 33.566893; -81.808377﻿ (Graniteville Historic District) | Aiken | Textile mill town with Gothic revival church and carpenter gothic homes |
| 28 | Hampton Plantation | Hampton Plantation More images | April 15, 1970 (#70000582) | McClellanville 33°11′54″N 79°26′16″W﻿ / ﻿33.198333°N 79.437778°W﻿ / 33.198333; -79.437778﻿ (Hampton Plantation) | Charleston | "South Carolina's finest example of a large two-and-a-half frame Georgian plantation house" |
| 29 | Dubose Heyward House | Dubose Heyward House More images | November 11, 1971 (#71000749) | Charleston 32°46′29″N 79°55′45″W﻿ / ﻿32.774663°N 79.929029°W﻿ / 32.774663; -79.929029﻿ (Dubose Heyward House) | Charleston | Home of Dubose Heyward, author of the novel Porgy. |
| 30 | Heyward-Washington House | Heyward-Washington House More images | April 15, 1970 (#70000576) | Charleston 32°46′31″N 79°55′45″W﻿ / ﻿32.775337°N 79.929125°W﻿ / 32.775337; -79.929125﻿ (Heyward-Washington House) | Charleston | Residence of George Washington during his 1792 visit to Charleston |
| 31 | Hibernian Hall | Hibernian Hall More images | November 7, 1973 (#73001686) | Charleston 32°46′39″N 79°55′52″W﻿ / ﻿32.777469°N 79.931148°W﻿ / 32.777469; -79.931148﻿ (Hibernian Hall) | Charleston | |
| 32 | Hopsewee | Hopsewee More images | November 11, 1971 (#71000782) | Georgetown 33°12′38″N 79°23′05″W﻿ / ﻿33.210556°N 79.384722°W﻿ / 33.210556; -79.384722﻿ (Hopsewee) | Georgetown | Plantation mansion built in 1749; the birthplace of Thomas Lynch Jr. |
| 33 | Huguenot Church | Huguenot Church More images | November 7, 1973 (#73001687) | Charleston 32°46′41″N 79°55′46″W﻿ / ﻿32.778090°N 79.929312°W﻿ / 32.778090; -79.929312﻿ (Huguenot Church) | Charleston | Gothic Revival church built in 1844; designed by architect E. B. White |
| 34 | Kahal Kadosh Beth Elohim | Kahal Kadosh Beth Elohim More images | June 19, 1980 (#78002499) | Charleston 32°46′55″N 79°55′59″W﻿ / ﻿32.781979°N 79.932948°W﻿ / 32.781979; -79.932948﻿ (Kahal Kadosh Beth Elohim) | Charleston | Greek revival building from 1840; second oldest synagogue in continuous use in the United States |
| 35 | USS Laffey | USS Laffey More images | January 14, 1986 (#83002189) | Mount Pleasant 32°47′16″N 79°54′28″W﻿ / ﻿32.787883°N 79.907744°W﻿ / 32.787883; -79.907744﻿ (USS Laffey) | Charleston | A destroyer |
| 36 | Lancaster County Courthouse | Lancaster County Courthouse More images | November 7, 1973 (#71000788) | Lancaster 34°43′17″N 80°46′17″W﻿ / ﻿34.721264°N 80.771369°W﻿ / 34.721264; -80.771369﻿ (Lancaster County Courthouse) | Lancaster | Courthouse in continuous use since 1828; designed by Robert Mills |
| 37 | Lancaster County Jail | Lancaster County Jail More images | November 7, 1973 (#71000789) | Lancaster 34°43′06″N 80°46′17″W﻿ / ﻿34.718335°N 80.771270°W﻿ / 34.718335; -80.771270﻿ (Lancaster County Jail) | Lancaster | Former jail building built in 1823, virtually unaltered work of Robert Mills, reflecting innovative changes in jail design he promoted |
| 38 | Joseph Manigault House | Joseph Manigault House More images | November 7, 1973 (#73001688) | Charleston 32°47′19″N 79°56′08″W﻿ / ﻿32.788703°N 79.935558°W﻿ / 32.788703; -79.935558﻿ (Joseph Manigault House) | Charleston | Home designed by Gabriel Manigault for his brother |
| 39 | Market Hall and Sheds | Market Hall and Sheds More images | November 7, 1973 (#73001689) | Charleston 32°46′51″N 79°55′53″W﻿ / ﻿32.780720°N 79.931515°W﻿ / 32.780720; -79.931515﻿ (Market Hall and Sheds) | Charleston | Greek Revival meat market with two blocks of sheds where vegetables, fish, etc., were sold |
| 40 | Marshlands | Marshlands More images | November 7, 1973 (#73001674) | Beaufort 32°26′01″N 80°39′57″W﻿ / ﻿32.433520°N 80.665831°W﻿ / 32.433520; -80.665831﻿ (Marshlands) | Beaufort | Home of Dr. James Robert Verdier, who discovered a treatment for yellow fever |
| 41 | Middleburg Plantation | Middleburg Plantation More images | April 15, 1970 (#70000568) | Huger 33°04′52″N 79°50′35″W﻿ / ﻿33.081111°N 79.843056°W﻿ / 33.081111; -79.843056﻿ (Middleburg Plantation) | Berkeley | One of the earliest frame plantation houses in the state |
| 42 | Middleton Place | Middleton Place More images | November 11, 1971 (#71000770) | Summerville 32°53′59″N 80°08′12″W﻿ / ﻿32.899722°N 80.136667°W﻿ / 32.899722; -80.136667﻿ (Middleton Place) | Dorchester | Plantation mansion and ornamental gardens on the Ashley River |
| 43 | Millford Plantation | Millford Plantation More images | November 7, 1973 (#71000808) | Pinewood 33°44′54″N 80°32′15″W﻿ / ﻿33.7484°N 80.53745°W﻿ / 33.7484; -80.53745﻿ (Millford Plantation) | Sumter | A monumental 2-story Greek Revival mansion built in 1839 and meticulously restored in the early 1990s. |
| 44 | Mills Building, South Carolina State Hospital | Mills Building, South Carolina State Hospital More images | November 7, 1973 (#70000890) | Columbia 34°00′55″N 81°02′03″W﻿ / ﻿34.015160°N 81.034151°W﻿ / 34.015160; -81.034151﻿ (Mills Building, South Carolina State Hospital) | Richland | Designed by Robert Mills, used from 1827 to 1937; "the oldest building in the country to be used continuously as a mental institution and one of the first mental hospitals built with public funds" |
| 45 | Clark Mills Studio | Clark Mills Studio More images | December 21, 1965 (#66000703) | Charleston 32°46′36″N 79°55′46″W﻿ / ﻿32.776597°N 79.929503°W﻿ / 32.776597; -79.929503﻿ (Clark Mills Studio) | Charleston | Studio of self-taught sculptor Clark Mills |
| 46 | Robert Mills House | Robert Mills House More images | November 7, 1973 (#70000595) | Columbia 34°00′34″N 81°01′45″W﻿ / ﻿34.009444°N 81.029167°W﻿ / 34.009444; -81.029167﻿ (Robert Mills House) | Richland | Home designed by architect Robert Mills |
| 47 | Mulberry Plantation | Mulberry Plantation More images | October 9, 1960 (#66000697) | Moncks Corner 33°08′31″N 80°01′04″W﻿ / ﻿33.141944°N 80.017778°W﻿ / 33.141944; -80.017778﻿ (Mulberry Plantation) | Berkeley | Built in 1714 for a Royal governor; one of the earliest plantation homes in the United States |
| 48 | Mulberry Plantation (James and Mary Boykin Chesnut House) | Mulberry Plantation (James and Mary Boykin Chesnut House) More images | February 16, 2000 (#80003673) | Camden 34°12′24″N 80°35′31″W﻿ / ﻿34.206528°N 80.591944°W﻿ / 34.206528; -80.591944﻿ (Mulberry Plantation (James and Mary Boykin Chesnut House)) | Kershaw | Home of Mary Boykin Chesnut and source for her Civil War-time diary describing southern society, "acknowledged as the most important piece of Confederate literature" |
| 49 | Ninety-Six and Star Fort | Ninety-Six and Star Fort More images | November 7, 1973 (#69000169) | Ninety Six 34°08′49″N 82°01′28″W﻿ / ﻿34.146944°N 82.024444°W﻿ / 34.146944; -82.024444﻿ (Ninety-Six and Star Fort) | Greenwood | |
| 50 | Old Marine Hospital | Old Marine Hospital More images | November 7, 1973 (#73001690) | Charleston 32°46′39″N 79°56′15″W﻿ / ﻿32.777621°N 79.937483°W﻿ / 32.777621; -79.937483﻿ (Old Marine Hospital) | Charleston | Gothic Revival design by Robert Mills built in 1833 to serve sick sailors and other transients |
| 51 | Parish House of the Circular Congregational Church | Parish House of the Circular Congregational Church More images | November 7, 1973 (#73001683) | Charleston 32°46′45″N 79°55′53″W﻿ / ﻿32.779032°N 79.931308°W﻿ / 32.779032; -79.931308﻿ (Parish House of the Circular Congregational Church) | Charleston | Parish house designed by Robert Mills |
| 52 | Penn School Historic District | Penn School Historic District More images | December 2, 1974 (#74001824) | Frogmore 32°23′18″N 80°34′31″W﻿ / ﻿32.3883°N 80.5753°W﻿ / 32.3883; -80.5753﻿ (Penn School Historic District) | Beaufort | School for freed slaves, Gullahs, on St. Helena Island which was occupied by the Union near the outset of the American Civil War |
| 53 | Pompion Hill Chapel | Pompion Hill Chapel More images | April 15, 1970 (#70000567) | Huger 33°05′12″N 79°50′12″W﻿ / ﻿33.086667°N 79.836667°W﻿ / 33.086667; -79.836667﻿ (Pompion Hill Chapel) | Berkeley | Episcopal chapel built in 1763, unaltered |
| 54 | Powder Magazine | Powder Magazine More images | September 27, 1989 (#72001200) | Charleston 32°46′47″N 79°55′47″W﻿ / ﻿32.779656°N 79.929791°W﻿ / 32.779656; -79.929791﻿ (Powder Magazine) | Charleston | The oldest public building in the city |
| 55 | Joseph H. Rainey House | Joseph H. Rainey House More images | April 20, 1984 (#84003877) | Georgetown 33°22′07″N 79°17′02″W﻿ / ﻿33.368607°N 79.283817°W﻿ / 33.368607; -79.283817﻿ (Joseph H. Rainey House) | Georgetown | Home of the first black U.S. Congressman, Joseph H. Rainey, a former slave |
| 56 | Robert Barnwell Rhett House | Robert Barnwell Rhett House More images | November 7, 1973 (#73001691) | Charleston 32°47′11″N 79°56′33″W﻿ / ﻿32.786250°N 79.942502°W﻿ / 32.786250; -79.942502﻿ (Robert Barnwell Rhett House) | Charleston | Home of Robert Barnwell Rhett, an extreme secessionist politician, a leading fire-eater at the Nashville Convention of 1850, which failed to endorse his aim of secession |
| 57 | Robert William Roper House | Robert William Roper House More images | November 7, 1973 (#73001692) | Charleston 32°46′14″N 79°55′42″W﻿ / ﻿32.770529°N 79.928419°W﻿ / 32.770529; -79.928419﻿ (Robert William Roper House) | Charleston | |
| 58 | Nathaniel Russell House | Nathaniel Russell House More images | November 7, 1973 (#71000750) | Charleston 32°46′27″N 79°55′51″W﻿ / ﻿32.774177°N 79.930737°W﻿ / 32.774177; -79.930737﻿ (Nathaniel Russell House) | Charleston | An Adamesque house completed in 1808 |
| 59 | Edward Rutledge House | Edward Rutledge House More images | November 11, 1971 (#71000751) | Charleston 32°46′34″N 79°56′01″W﻿ / ﻿32.776202°N 79.933560°W﻿ / 32.776202; -79.933560﻿ (Edward Rutledge House) | Charleston | Home of Edward Rutledge, a signer of the Declaration of Independence, and a governor of South Carolina |
| 60 | John Rutledge House | John Rutledge House More images | November 7, 1973 (#71000752) | Charleston 32°46′34″N 79°56′01″W﻿ / ﻿32.776231°N 79.933563°W﻿ / 32.776231; -79.933563﻿ (John Rutledge House) | Charleston | Home of Gov. John Rutledge, a signer of the U.S. Constitution. |
| 61 | St. James Church, Goose Creek | St. James Church, Goose Creek More images | April 15, 1970 (#70000566) | Goose Creek 32°58′25″N 80°01′47″W﻿ / ﻿32.973616°N 80.029594°W﻿ / 32.973616; -80.029594﻿ (St. James Church, Goose Creek) | Berkeley | Episcopal chapel |
| 62 | St. James Church, Santee | St. James Church, Santee More images | April 15, 1970 (#70000581) | Georgetown 33°10′13″N 79°27′56″W﻿ / ﻿33.170166°N 79.46569°W﻿ / 33.170166; -79.46569﻿ (St. James Church, Santee) | Charleston | |
| 63 | Saint Michael's Episcopal Church | Saint Michael's Episcopal Church More images | October 9, 1960 (#66000704) | Charleston 32°46′33″N 79°55′51″W﻿ / ﻿32.775963°N 79.930931°W﻿ / 32.775963; -79.930931﻿ (Saint Michael's Episcopal Church) | Charleston | Built in 1750s, Charleston's oldest church building |
| 64 | St. Philip's Episcopal Church | St. Philip's Episcopal Church More images | November 7, 1973 (#73001695) | Charleston 32°46′44″N 79°55′46″W﻿ / ﻿32.778874°N 79.929469°W﻿ / 32.778874; -79.929469﻿ (St. Philip's Episcopal Church) | Charleston | Church with E. B. White-designed steeple |
| 65 | St. Stephen's Episcopal Church | St. Stephen's Episcopal Church More images | April 15, 1970 (#70000570) | St. Stephen 33°24′19″N 79°55′00″W﻿ / ﻿33.4054°N 79.9166°W﻿ / 33.4054; -79.9166﻿ (St. Stephen's Episcopal Church) | Berkeley | A small Georgian brick country church with a high gambrel roof. |
| 66 | Simmons-Edwards House | Simmons-Edwards House More images | November 7, 1973 (#71000753) | Charleston 32°46′22″N 79°56′02″W﻿ / ﻿32.7729°N 79.93397°W﻿ / 32.7729; -79.93397﻿ (Simmons-Edwards House) | Charleston | Known as the "Pineapple Gate House" by locals, referring to finials upon its large brick gates |
| 67 | Robert Smalls House | Robert Smalls House More images | May 30, 1973 (#74001823) | Beaufort 32°26′07″N 80°40′05″W﻿ / ﻿32.435156°N 80.668186°W﻿ / 32.435156; -80.668186﻿ (Robert Smalls House) | Beaufort | Post-Civil War home of U.S. congressman Robert Smalls, a former slave who commandeered a Confederate ship out to Union lines |
| 68 | Snee Farm | Snee Farm More images | November 7, 1973 (#73001702) | Mount Pleasant 32°50′46″N 79°49′29″W﻿ / ﻿32.846111°N 79.824722°W﻿ / 32.846111; -79.824722﻿ (Snee Farm) | Charleston | Home of early South Carolina Governor Charles Pinckney. |
| 69 | Snow's Island | Upload image | December 2, 1974 (#73001708) | Across the Peedee River from Dunham Bluff, near Johnsonville 33°50′13″N 79°20′28″W﻿ / ﻿33.8369°N 79.3411°W﻿ / 33.8369; -79.3411﻿ (Snow's Island) | Florence | Revolutionary War era refuge of the "Swamp Fox", Francis Marion |
| 70 | South Carolina State House | South Carolina State House More images | May 11, 1976 (#70000598) | Columbia 34°00′02″N 81°01′59″W﻿ / ﻿34.000433°N 81.033147°W﻿ / 34.000433; -81.033147﻿ (South Carolina State House) | Richland | This Greek Revival capitol building was completed in 1907, with major renovations in 1959 and 1998. |
| 71 | Stono River Slave Rebellion Site | Stono River Slave Rebellion Site | May 30, 1974 (#74001840) | Rantowles 32°47′08″N 80°08′44″W﻿ / ﻿32.785501°N 80.145560°W﻿ / 32.785501; -80.145560﻿ (Stono River Slave Rebellion Site) | Charleston | Beginning point of the earliest slave revolt in the United States. |
| 72 | Colonel John Stuart House | Colonel John Stuart House More images | November 7, 1973 (#70000578) | Charleston 32°46′28″N 79°56′02″W﻿ / ﻿32.774370°N 79.933807°W﻿ / 32.774370; -79.933807﻿ (Colonel John Stuart House) | Charleston | Home of Colonel John Stuart. |
| 73 | Unitarian Church | Unitarian Church More images | November 7, 1973 (#73001696) | Charleston 32°46′41″N 79°56′04″W﻿ / ﻿32.778149°N 79.934554°W﻿ / 32.778149; -79.934554﻿ (Unitarian Church) | Charleston | Church built in 1772 and reworked in Gothic style during 1852-1854 |
| 74 | Denmark Vesey House | Denmark Vesey House More images | May 11, 1976 (#76001698) | Charleston 32°46′56″N 79°56′28″W﻿ / ﻿32.782209°N 79.941180°W﻿ / 32.782209; -79.941180﻿ (Denmark Vesey House) | Charleston | Said to be the home of Denmark Vesey, who was accused of plotting slave rebellion in 1822 and executed |
| 75 | Woodlands | Woodlands More images | November 11, 1971 (#71000742) | Bamberg 33°17′27″N 80°55′53″W﻿ / ﻿33.29085°N 80.931271°W﻿ / 33.29085; -80.931271﻿ (Woodlands) | Bamberg | The primary residence of author William Gilmore Simms, whose main house was burned in 1865; the remaining wing and several outbuildings constitute a literary landmark. |
| 76 | USS Yorktown | USS Yorktown More images | January 14, 1986 (#82001519) | Mount Pleasant 32°47′20″N 79°54′31″W﻿ / ﻿32.788792°N 79.908588°W﻿ / 32.788792; -79.908588﻿ (USS Yorktown) | Charleston | Famous World War II aircraft carrier |

## Historic areas of the National Park System in South Carolina

National Historic Sites, National Historic Parks, National Memorials, and certain other areas listed in the National Park system are historic landmarks of national importance that are highly protected already, often before the inauguration of the NHL program in 1960, and are then often not also named NHLs per se. There are five of these in South Carolina. The National Park Service lists these five together with the NHLs in the state, The Charles Pinckney National Historic Site (also known as Snee Farm) and Ninety Six National Historic Site are also NHLs and are listed above. The remaining three are:
| | Landmark name | Date established | Location | County | Description |
| 1 | Cowpens National Battlefield | March 4, 1929 | Gaffney | Cherokee | Site of Battle of Cowpens in 1781 |
| 2 | Fort Sumter National Monument | April 28, 1948 | Charleston | Charleston | First shots of the American Civil War were fired on January 9, 1861, and the Battle of Fort Sumter raged from April 12 to April 13. |
| 3 | Kings Mountain National Military Park | March 3, 1931 | Blacksburg | Cherokee | Site of Battle of Kings Mountain on 7 October 1780 |

## Former NHLs in South Carolina

The nuclear-powered commercial vessel NS Savannah was moved to Virginia. Piedmont Number One, a historic textile mill, burned in 1983.
| | Landmark name | Date designated | Date moved or withdrawn | Locality | County | Description |
| 1 | NS Savannah | July 17, 1991 | 1994 | Patriot's Point, Charleston | Charleston | Nuclear-powered merchant cargo and passenger vessel. It was at Patriot's Point from 1982 until 1994, when it was removed to Baltimore, Maryland. It has since been moved to Virginia. |
| 2 | Piedmont Number One | June 2, 1978 | March 5, 1986 | Piedmont | Greenville | A historic Southern textile mill that burned in 1983. Its National Historic Landmark designation was removed on March 5, 1986. |
| 3 | USS Clamagore | June 29, 1989 | September 2, 2024 | Mount Pleasant | Charleston | Scrapped in 2022. |