# List of fictional characters with disabilities

Fictional characters with disabilities appear in various mediums, including novels, comics, television, and movies. A disability may be readily visible, or invisible in nature. Some examples of invisible disabilities include intellectual disabilities, autism spectrum disorder, attention deficit hyperactivity disorder, mental disorders, asthma, epilepsy, allergies, migraines, arthritis, and chronic fatigue syndrome. There are many different causes of disability that often affect basic activities of daily living, such as eating, dressing, transferring, and maintaining personal hygiene; or advanced activities of daily living such as shopping, food preparation, driving, or working. However, causes of disability are usually determined by a person's capability to perform the activities of daily life.
Due to the number of entries, this page does not include autistic fictional characters.

## Literature

| Year | Character | Book(s) | Author(s) | Disability |
| 1995 | Nessarose, AKA Wicked Witch of the East | Wicked | Gregory Maguire | Born without arms. |
| 1851 | Captain Ahab | Moby Dick | Herman Melville | A whale bit off Ahab's leg, and he stands on what's left of the bone. The sound of his ivory limb echoes on the deck. Ahab experiences a constant, piercing pain in his groin that represents the world's suffering. |
| 1964 | Barquentine | Gormenghast series | Mervyn Peake | One-legged, hunchbacked dwarf. |
| 2003 | Christopher | The Curious Incident of the Dog in the Night-Time | Mark Haddon | Christopher is ostensibly diagnosed with Asperger's Syndrome, which is now included in the autistic spectrum |
| 1928 | Clifford | Lady Chatterley's Lover | D. H. Lawrence | Clifford is dependent on a wheelchair for mobility. Clifford's disability is a significant metaphorical form in the novel. The novel satirizes Clifford's technological obsessions, focus on "the life of the mind", and insistence on industrial wealth. |
| 1911 | Colin Craven | The Secret Garden | Frances Hodgeson Burnett | Colin Craven is a character who experiences a disability that is described as a hunchback and an inability to walk. |
| 2016 | Jams Cogan | Thimble Monkey (book series) | Jon Blake | Jams has Cerebral Palsy, and a monkey. |
| 1929 | Benjy Compson | The Sound and the Fury | William Faulkner | Benjy is most likely autistic with synesthesia, as his whole life experience based on smells, shapes, and sounds |
| 1976 | Harry Hardacre | The Hardacres (book series) | C. L. Skelton | Harry has Little's Disease |
| 1904 | Captain Hook | Peter and Wendy | J. M. Barrie | A pirate with a missing hand |
| 1996 | Tyrion Lannister | A Song of Ice and Fire | George R. R. Martin | An unspecified type of dwarfism and severe facial disfigurement. |
| 2012 | Adam Parrish | The Raven Cycle | Maggie Stiefvater | In the first book of the series, Adam becomes deaf in his left ear due to abuse. |
| 2012 | Hazel Grace Lancaster, Augustus Waters, and several other characters | The Fault in our Stars | John Green | The book is about characters with several types of cancer and resulting disabilities including a blind character and one with a prosthetic leg. |
| 2015 | Kaz Brekker | Six of Crows | Leigh Bardugo | Kaz has a limp and uses a cane. He also experiences post-traumatic stress disorder. These are major parts of his experiences and development throughout the Six of Crows duology. |
| 1831 | Quasimodo | The Hunchback of Notre-Dame | Victor Hugo | Quasimodo is born a hunchback, is half-blind, and becomes deaf due to his living in the bell tower of the cathedral. |
| 1883 | Long John Silver | Treasure Island | Treasure Island | A pirate with a missing leg, and eyepatch and another who has lost his sight. |
| 1883 | Blind Pew | Treasure Island | Treasure Island | A pirate with a missing leg, and eyepatch and another who has lost his sight. |
| 1973 | Mr Johnny Gotobed | Carrie's War | Nina Bawden | He has both communication and learning disabilities. |
| 1818 | The Monster | Frankenstein | Mary Shelly | A man made from the bodies of other people, imperfect, abused because of his visible differences and communication disabilities. |
| 1818 | DeLacey | Frankenstein | Mary Shelly | An old blind man who cannot see the monster so isn't prejudiced by his sight, and offers the only genuine friendship the monster has ever experienced, |
| 2001 | Shawn | Stuck In Neutral | Terry Trueman | Stuck in Neutral is a young adult with cerebral palsy and explores themes of quality of life, ableism and euthanasia. |
| 1838 | Smike | Nicholas Nickleby | Charles Dickens | He has deformed limbs and has intellectual and communication difficulties related to the abuse he has suffered. |
| 1915 | Gregor Samsa | The Metamorphosis | Franz Kafka | Gregor Samsa's transformation and the changes of attitudes towards him, except those in his immediate family, is a metaphor for the lived experience of physical and visible disability. The story's themes resonate with critical disability theory. |
| 1843 | Tiny Tim | A Christmas Carol | Charles Dickens | Tiny Tim is believed to have had either rickets, tuberculosis (TB), polio, and/or cerebral palsy. |
| 1978 | Walter | Walter | David Cook | He has learning and communication disabilities. |
| 1937 | Lennie Small | Of Mice and Men | John Steinbeck | He is a migrant worker with learning and communication disabilities. He relies on his best friend for support. |
| 1937 | Candy | Of Mice and Men | John Steinbeck | Candy is an old man with a stooped posture and no right hand, which he lost in an accident on the ranch. |
| 1937 | Crooks | Of Mice and Men | John Steinbeck | Crooks has a crooked spine from an accident with a horse. Crooks is doubly marginalized by his disability and race. |

## Movies (Live Action)

| Year | Character | Film | Character's Disability | Actor |
| 2019 | Gary | Joker | Dwarfism | Leigh Gill |
| 2017 | Dr Strange | Thor: Ragnarok | He suffered irreversible nerve damage to his hands. His hands are permanently injured. Strange's hands shake, his hands clench up or lose grip on objects without warning, he experiences painful spasms and can occasionally become paralyzed. | Benedict Cumberbatch |
| 2018 | Dr Strange | Avengers: Infinity War | He suffered irreversible nerve damage to his hands | Benedict Cumberbatch |
| 2019 | Dr Strange | Avengers: Endgame | He suffered irreversible nerve damage to his hands | Benedict Cumberbatch |
| 2021 | Dr Strange | Spider-Man: No Way Home | He suffered irreversible nerve damage to his hands | Benedict Cumberbatch |
| 2022 | Dr Strange | Doctor Strange in the Multiverse of Madness | He suffered irreversible nerve damage to his hands | Benedict Cumberbatch |
| 1992 | Frank Slade | Scent of a Woman | Blindness | Al Pacino |
| 2002 | Barry Egan | Punch-Drunk Love | Barry has autism and OCD. | Adam Sandler |
| 2004 | Ivy Elizabeth Walker | The Village | Blindness | Bryce Dallas Howard |
| 2007 | H.W. Plainview | There Will Be Blood | Deafness | Dillon Freasier & Russell Harvard |
| 2017 | James | Three Billboards Outside Ebbing, Missouri | Dwarfism | Peter Dinklage |
| 2015 | Imperator Furiosa | Mad Max: Fury Road | She is missing an arm and uses a robotic prosthetic. | Charlize Theron |
| 2015 | Marie Nakazawa | Library Wars: The Last Mission | She is deaf in one ear and hard of hearing in the other, using a hearing aid. | Tao Tsuchiya |
| 2016 | Lee Chandler | Manchester by the Sea | Lee experiences post-traumatic stress disorder. | Casey Affleck |
| 2021 | Jie | Godzilla vs. Kong | Deafness | Kaylee Hottle |
| 2014 | Gazelle | Kingsman | Double leg amputee. | Sofia Boutella |
| 2024 | Nessarose | Wicked | Wheelchair user | Marissa Bode |
| 2023 | Tommy Olsen | The Unseen | Cerebral Palsy | RJ Mitte |
| 2023 | Sam | Monico Perseus | Downs Syndrome | Sam Barnard |
| 2022 | Clifford | Lady Chatterley's Lover | Physical disability from war injuries | Matthew Duckett |
| 2022 | Phil | American Dreamer | Dwarfism | Peter Dinklage |
| 2022 | Barbara Lisicki | Then Barbara Met Alan | Wheelchair User | Ruth Madeley |
| 2022 | Alan Holdsworth | Then Barbara Met Alan | Physical Disability | Arthur Hughes |
| 2022 | Lorcan | An Irish Goodbye | Downs Syndrome | James Martin |
| 2021 | Makkari | Eternals | Deaf | Lauren Ridloff |
| 2021 | Tim | Help | Physical Disability | Arthur Hughes |
| 2021 | Cyrano | Cyrano | Visible Disability, in this version Dwarfism | Peter Dinklage |
| 2021 | Garrick | Infinite | Wheelchair User | Liz Carr |
| 2021 | Sophie | See For Me | Blindness | Skyler Davenport |
| 2021 | Kackie Rossi | Coda | Deafness | Marlee Maitlin |
| 2021 | Frank Rossi | Coda | Deafness | Troy Kotsur |
| 2021 | Leo Rossi | Coda | Deafness | Daniel Durant |
| 2020 | Izzy Simmons | Christmas Ever After | Wheelchair User | Ali Stroker |
| 2020 | Roman Lunyov | I Care A Lot | Dwarfism | Peter Dinklage |
| 2020 | Steve | The Oak Room | Cerebral Palsy | RJ Mitte |
| 2023 | Elliot | Battery | Wheelchair User | Zak Ford-Williams |
| 2020 | Daughter | Run | Wheelchair User | Kiera Allen |
| 2019 | Diane | Sound of Metal | Deafness | Lauren Ridloff |
| 2019 | Travis | Standing Up for Sunny | Cerebral Palsy | RJ Mitte |
| 2019 | Conal | Ups and Downs | Downs Syndrome | James Martin |
| 2019 | Zak | The Peanut Butter Falcon | Downs Syndrome | Zack Gottsagen |
| 2018 | Arrow | Spare Room | Downs Syndrome | Cole Sibus |
| 2018 | Regan Abbot | A Quiet Place | Deafness | Millicent Simmonds |
| 2017 | Rose | Wonderstruck | Deafness | Millicent Simmonds |
| 2013 | Tim | The Last House | Cerebral Palsy | RJ Mitte |
| 2009 | Jimmy Loveit | Unarmed But Dangerous | Limb Difference | Matt Fraser |
| 2008 | Laura Miller | Sweet Nothing In My Ear | Deafness | Marlee Maitlin |
| 2003 | Finbar McBride | The Station Agent | Dwarfism | Peter Dinklage |
| 1988 | Eric Cruise | Mac and Me | Wheelchair User | Jade Calegory |
| 1952 | Larry Nevins | Bright Victory | Blindness | Arthur Kennedy |
| 1965 | Selina D'Arcey | A Patch of Blue | Blindness | Elizabeth Hartman |
| 1967 | Susy Hendrix | Wait Until Dark | Blindness | Audrey Hepburm |
| 1969 | Singer | The Heart is a Lonely Hunter | Deafness and Muteness | Alan Arkin |
| 1985 | Mr Will | Places In The Heart | Blindness | John Malkovich |
| 1989 | Raymond Babbitt | Rain Man | Autistic Spectrum Condition | Dustin Hoffman |
| 1994 | Arnie Grape | What's Eating Gilbert Grape | Learning and Communication Disorders | Leonardo DiCaprio |
| 1994 | Forrest Gump | Forrest Gump | Learning Disability and Developmental Disorder | Tom Hanks |
| 2001 | Sam Dawson | I Am Sam | Developmental Disorder | Sean Penn |
| 2017 | Philip Lacasse | The Upside | Wheelchair User and Paralysis | Bryan Cranston |
| 2007 | Art Honeyman | Music Within | Cerebral Palsy | Michael Sheen |
| 2016 | Trevor | The Fundamentals of Caring | Wheelchair User | Craig Roberts |
| 1999 | Lincoln Rhyme | The Bone Collector | Quadriplegic | Denzel Washington |
| 2004 | Rory O'Shae | Inside Im Dancing | Quadriplegic Wheelchair User | James McAvoy |
| 1954 | Hal Jeffries | Rear Window | Wheelchair User | James Stewart |
| 2021 | Music | Music | Autistic Spectrum Condition | Maddie Ziegler |
| 2002 | Bill Porter | Door to Door | Cerebral Palsy | Williams H. Macey |
| 1989 | Nick Parker | Blind Fury | Blindness | Rutger Hauer |
| 2002 | Charles Xavier | X-Men | Wheelchair User | Patrick Stewart |
| 1982 | Walter | Walter | Learning Disabilities | Ian McKellen |
| 2023 | Oompa Loompa | Wonka | Short Stature | Hugh Grant |
| 2016 | Will Traynor | Me Before You | Paralysed | Sam Clafin |
| 2014 | Laila | Margarita with a Straw | Cerebral Palsy | Kalki Koechlin |
| 2024 | Maker Keeper | Dune: Part Two | Short Stature (Dwarfism) | Alison Halstead |
| 1992 | Lennie Small | Of Mice and Men | Learning Disabilities | John Malkovich |
| 2014 | Benjy Compson | The Sound and the Fury | Autism | James Franco |
| 1988 | Willow Ulfgood | Willow | Short Stature (Dwarfism) | Warwick Davis |

## Television (Live Action)

| First year | Character | Series | Character's Disability | Actor | Ref. |
| 2024 | Harry Hardacre | The Hardacres | Little's disease | Zak Ford-Williams | |
| 2024 | KB | Star Wars: Skeleton Crew | Physical Disability | Kyriana Kratter | |
| 2024 | Freya | We Might Regret This | Wheelchair User | Kyla Harris | |
| 2009 | Arthur "Artie" Abrams | Glee | Paraplegic wheelchair user. | Kevin McHale | |
| 2002 | Butchie | The Wire | Butchie is blind and is portrayed by a blind actor. | S. Robert Morgan | |
| 2011 | Martin Goodman | Friday Night Dinner | Hard of hearing and uses a hearing aid. | Paul Ritter | |
| 1987 | Geordi La Forge | Star Trek: The Next Generation | Blind since birth, and uses technological devices to allow him to see. | LeVar Burton | |
| 2023 | Kirsty Millar | Doctors | Dwarfism | Kiruna Stamell | |
| 1989 | Corky Thatcher | Life Goes On | First major character with Down syndrome on a television series, portrayed by a person who also has Down syndrome. | Chris Burke | |
| 2018 | Penny Stevenson | Doctors | She was born with a right arm that ends just below the elbow. | Cerrie Burnell | |
| 1994 | Kerry Weaver | ER | Limp in her gait due to congenital hip dysplasia | Laura Innes | |
| 2004 | Gregory House | House M.D. | An aneurysm in his thigh had clotted, leading to an infarction and causing his quadriceps muscle to become necrotic. Dead muscle was removed and this resulted in the partial loss of use in his leg and chronic pain, meaning he has to rely on a cane and vicodin to get through life. | Hugh Laurie | |
| 2008 | Walter White Jr. | Breaking Bad | He has cerebral palsy, which manifests itself in speech difficulties and impaired motor control, requiring crutches to walk. | RJ Mitte | |
| 2008 | Hector Salamanca | Breaking Bad | Hector uses a wheelchair. | Mark Margolis | |
| 2013 | Clarissa Mullery | Silent Witness | She has Arthrogryposis multiplex congenita, a rare genetic condition that limits joint movement. She is a mobility scooter user. | Liz Carr | |
| 2019 | Tim | Jerk | Tim the character and Tim the actor/writer both have Cerebral Palsy. | Tim Renkow | |
| 2017 | Cherry Dorrington | Harlots | Dwarfism | Francesca Mills | |
| 2023 | Owen Davies | Better | Owen starts the series as non-disabled but catches meningitis. His mobility and speech are both profoundly affected and the actor used his own condition, Cerebral Palsy, and his experience of having to learn to walk again after major surgery to portray the character's journey through rehabilitation. | Zak Ford-Williams | |
| 2024 | Matthew Shardlake | Shardlake | He has radial dysplasia affecting his right arm. | Arthur Hughes | |
| 2023 | Mike | Mobility | BAFTA winning comedy short. Mike has Cerebral Palsy and uses a walking frame. | Jack Carroll | |
| 2023 | Sonny | Mobility | Sonny has an unspecified condition but is a wheelchair user. | Zak Ford-Williams | |
| 2023 | Dan | Mobility | Dan has Down syndrome. | Ruben Reuter | |
| 2024 | Lord Remington | Bridgerton | Unknown condition, but he is a bath chair user | Zak Ford-Williams | |
| 2024 | Oswald 'Oz' Cobb | The Penguin | Physically Disabled | Colin Farrell | |
| 2024 | Victor Aguilar | The Penguin | Stammer | Rhenzy Feliz | |
| 2023 | Paul | Shrinking | Parkinson's Disease | Harrison Ford | |
| 2012 | Richard III | The Hollow Crown | Physical Disability | Benedict Cumberbatch | |
| 2015 | Garrett | Superstore | Wheelchair User | Colton Dunn | |
| 2011 | Tyrion Lannister | Game of Thrones | Short Stature (Dwarfism) | Peter Pinklage | |
| 2020 | Sue | CripTales | Wheelchair User | Ruth Madeley | |
| 2020 | Annette | CripTales | Wheelchair User | Carley Houston | |
| 2020 | Stacy Hadfield | CripTales | Limb Difference | Jackie Hagan | |
| 2020 | Hamish | CripTales | Cerebral Palsy | Robert Softley Gale | |
| 2020 | Mat | CripTales | Limb Difference | Mat Fraser | |
| 2020 | Meg | CripTales | Wheelchair User | Liz Carr | |
| 2011 | Warwick Davis | Life's Too Short | Short Stature (Dwarfism) | Warwick Davis | |
| 2014 | Paul the Illustrated Seal | American Horror Story, Freak Show | Limb Difference | Matt Fraser | |
| 2014 | Ma Petite | American Horror Story, Freak Show | Short Stature (Dwarfism) | Jyoti | |
| 2014 | Legless Suzi | American Horror Story, Freak Show | Limb Difference | Rose Siggins | |
| 2014 | Toulouse | American Horror Story, Freak Show | Short Stature (Dwarfism) | Drew Rin Varick | |
| 2014 | Salty | American Horror Story, Freak Show | Physical Disability, Learning Disability and Visible Difference | Christopher Neiman | |
| 2014 | Pepper | American Horror Story, Freak Show | Physical Disability, Learning Disability and Visible Difference | Naomi Grossman | |
| 2014 | Jimmy Darling | American Horror Story, Freak Show | Limb Difference | Evan Peters | |
| 2022 | Katie | Ralph and Katie | Downs Syndrome | Sarah Gordy | |
| 2022 | Ralph | Ralph and Katie | Downs Syndrome | Leon Harrop | |
| 2022 | Tina | This is Going To Hurt | Wheelchair User | Liz Carr | |
| 2022 | Ollie | Am I Being Unreasonable? | Short Stature (Dwarfism) | Lenny Rush | |
| 2018 | Connie | The Walking Dead | Deafness | Lauren Ridloff | |
| 2022 | Willow Ulfgood | Willow | Short Stature (Dwarfism) | Warwick Davis | |
| 2023 | Isaac Godwin | Sex Education | Wheelchair User | George Robinson | |
| 2021 | Tyler | Wolfe | Wheelchair User | Zak Ford-Williams | |
| 2010 | Amelia | The Silence | Deafness | Genevieve Barr | |
| 2012 | Reggie Jackson | Call The Midwife | Downs Syndrome | Daniel Laurie | |
| 1985 | Sil | Doctor Who | Short Stature and Mobility | Nabil Shaban | [147] [148] |
| 2018 | Hanne | Doctor Who | Blindness | Ellie Wallwork | [147] [148] |
| 2005 | Diane | Doctor Who | Limb Difference | Nadia Albina | [147] [148] |
| 2015 | Cass | Doctor Who | Deafness | Sophie Leigh Stone | [147] [148] |
| 2005 | Bescot | Doctor Who | Limb Difference | Rhiannon Clements | [147] [148] |
| 2023 | Shirley Bingham | Doctor Who | Wheelchair User | Ruth Madeley | [147] [148] |
| 2024 | Morris Gibbons | Doctor Who | Short Stature (Dwarfism) | Lenny Rush | [147] [148] |
| 1969 | Dom Issigri | Doctor Who | Vision Impairment | Esmond Knight | [147] [148] |
| 2005 | Porridge | Doctor Who | Short Stature (Dwarfism) | Warwick Davis | [147] [148] |
| 1968 | Detective Columbo | Columbo | Vision Impaired | Peter Falk | |
| 1967 | Robert T. Ironside | Ironside | Wheelchair User | Raymond Burr | |
| 2020 | Rebecca | Never Have I Ever | Downs Syndrome | Lily D. Moore | |
| 2014 | Miss Scott | Grantchester | Limb Difference | Melissa Johns | |
| 2015 | Helen Milton | Vera | Short Stature (Dwarfism) and Wheelchair User | Lisa Hammond | |
| 2014 | Donna Yates | East Enders | Short Stature (Dwarfism) and Wheelchair User | Lisa Hammond | |
| 2010 | Izzy Armstrong | Coronation Street | Wheelchair User | Cherylee Houston | |
| 2017 | Imogen Pascoe | Coronation Street | Limb Difference | Melissa Johns | |
| 2015 | Alex Warner | Coronation Street | Downs Syndrome | Liam Bairstow | |
| 2022 | Bobby Crawford | Coronation Street | Cerebral Palsy | Jack Carroll | |
| 2020 | Hannah Taylor | Life | Limb Difference | Melissa Johns | |
| 2018 | Ryan Stocks | Emmerdale | Cerebral Palsy | James Moore | |
| 2023 | Lacey Lloyd | Hollyoaks | Short Stature (Dwarfism) | Annabell Davis | |
| 2003 | Peter Hamil | Hollyoaks | Wheelchair User | Peter Mitchell | |
| 2022 | Freya Calder | Hollyoaks | Wheelchair User | Ellie Henry | |
| 2016 | Courtney Campbell | Hollyoaks | Wheelchair User | Amy Conachan | |
| 2011 | Harry | Trollied | Cerebral Palsy | Jack Carroll | |
| 2015 | Isobel Reilly | Home Fires | Blindness | Gillian Dean | |
| 2016 | Louise | Two Doors Down | Deafness | Sophie Leigh Stone | |
| 2022 | Ashley Wilton | The Chelsea Detective | Deafness | Sophie Leigh Stone | |
| 2023 | Sam Burrell | The Last of Us | Deafness | Keivonn Woodard | |
| 2019 | Baba Voss | See | Blindness | Jason Momoa | [167] [168] [169] |
| 2019 | Queen Kane | See | Blindness | Sylvia Hoeks | [167] [168] [169] |
| 2019 | Tamacti Jun | See | Blindness | Christian Camargo | [167] [168] [169] |
| 2019 | Charlotte | See | Blindness | Olivia Cheng | [167] [168] [169] |
| 2019 | Wren | See | Blindness | Eden Epstein | [167] [168] [169] |
| 2019 | Lord Harlan | See | Blindness | Tom Mison | [167] [168] [169] |
| 2019 | Paris | See | Blindness | Alfre Woodard | [167] [168] [169] |
| 2019 | Captain Gosset | See | Blindness | Martin Roach | [167] [168] [169] |
| 2019 | Bow Lion | See | Blindness | Yadira Guevara-Prip | [167] [168] [169] |
| 2019 | Tormada | See | Blindness | David Hewlett | [167] [168] [169] |
| 2019 | Toad | See | Blindness | Hoon Lee | [167] [168] [169] |
| 2019 | Ranger | See | Blindness | Michael Raymond-James | [167] [168] [169] |
| 2019 | Edo Voss | See | Blindness | Dave Bautista | [167] [168] [169] |
| 2017 | Roger Frosty | Loudermilk | Limb Difference | Matt Fraser | |
| 2019 | Raymond Van Gerrit | His Dark Materials | Limb Difference | Matt Fraser | |
| 2009 | Will | Cast Offs | Limb Difference | Matt Fraser | |
| 2009 | Carrie | Cast Offs | Short Stature (Dwarfism) | Kiruna Stamell | |
| 2009 | Dan | Cast Offs | Wheelchair User | Peter Mitchell | |
| 2009 | Gabriella | Cast Offs | Deafness | Sophie Woolley | |
| 2009 | April | Cast Offs | Facial Difference | Victoria Wright | |
| 2009 | Tom | Cast Offs | Blindness | Tim Gebelles | |
| 2022 | Morgan | Dodger | Short Stature (Dwarfism) | Lenny Rush | |
| 2000 | Barquentine | Gormenghast | Physical disability | Warren Mitchell | |

## Animated films and TV series

| First year | Character | Title | Character's Disability | Actor |
| 2010 | Hiccup | How to Train Your Dragon | Has a prosthetic left leg | Jay Baruchel |
| 2011 | Heinz Doofenshmirtz (2nd Dimension) | Phineas and Ferb the Movie: Across the 2nd Dimension | He has an eye-patch with a scar running over it, which covers his left eye socket. | Dan Povenmire |
| 2019 | Violet Evergarden | Violet Evergarden: Eternity and the Auto Memory Doll | With the war over, her arms were replaced with advanced metallic prosthetics, which she uses as a ghostwriter at a private postal company. | Yui Ishikawa |
| 2020 | Violet Evergarden | Violet Evergarden: The Movie | With the war over, her arms were replaced with advanced metallic prosthetics, which she uses as a ghostwriter at a private postal company. | Yui Ishikawa |
| 2017 | Red Action | OK K.O.! Let's Be Heroes | A cyborg teenage girl who is missing a leg and uses a prosthetic. | Kali Hawk |
| 2018 | Amaya | The Dragon Prince | Amaya is deaf and communicates in American Sign Language. | — |
| 2006 | Toph Beifong | Avatar: The Last Airbender | Blindness | Michaela Jill Murphy |
| 2016 | Christina | Elena of Avalor | Uses a wheelchair. | Montse Hernandez |
| 2018 | Violet Evergarden | Violet Evergarden | Uses metal prosthetic arms. | Yui Ishikawa |
| 2010 | Finn the Human | Adventure Time | Beginning in Season 6, he has a robotic, prosthetic arm, and previously a grass sword coming from his arm. | Jeremy Shada |
| 2010 | Gobber the Belch | How to Train Your Dragon | Has a prosthetic left arm and right leg | Craig Ferguson |
| 2018 | Gary Goodspeed | Final Space | He has a prosthetic, cybernetic arm. | Olan Rogers |
| 2016 | Izetta | Izetta: The Last Witch | She is a wheelchair user. | Himika Akaneya |
| 2018 | Kazi | The Dragon Prince | Sunfire Elf sign language interpreter. | Ashleica Edmond |
| 2020 | Eleanor Kimble | Spirit Riding Free: Riding Academy | Paraplegic wheelchair user portrayed by a disability advocate with Conradi-Hünermann syndrome. | Cassidy Marie Huff |
| 2020 | Lancelot | Wizards: Tales of Arcadia | Has a prosthetic left arm and shoulder | Rupert Penry-Jones |
| 2013 | Neopolitan | RWBY | Mute. | |
| 2013 | Yang Xiao Long | RWBY | Has a robotic prosthetic arm | Barbara Dunkelman |
| 1987 | Bart Simpson | The Simpsons | Has attention deficit hyperactivity disorder | Nancy Cartwright |
| 1999 | Joe Swanson | Family Guy | He is paraplegic and uses a wheelchair. | Patrick Warburton |
| 1997 | Ned Gerblanski | South Park | Missing his right arm, speaks with an electrolarynx | Trey Parker |
| 2000 | Timmy Burch | South Park | Has both palsy and tourette's, uses a wheelchair. | Trey Parker |
| 2001 | Jimmy Valmer | South Park | Ataxic cerebral palsy, exotropia, use of crutches to assist in equinus and crouch gait. | Trey Parker |
| 2004 | Nathan | South Park | Down syndrome and possible sociopathy. | Trey Parker |
| 2007 | Thomas | South Park | Tourette's syndrome | Matt Stone |
| 2008 | Scott Malkinson | South Park | Type 1 Diabetes and a speech impediment. | Matt Stone |
| 2019 | Sophie Gray | South Park | Type 1 Diabetes | Becca Scott |
| 2023 | Ringo | Blue Eye Samurai | Amputee | Masi Oka |
| 2023 | Dolph Laserhawk | Captain Laserhawk: A Blood Dragon Remix | Both his left arm and the right side of his face have been replaced with robotic prosthetics. | Nathaniel Curtis |
| 2023 | Pey'j | Captain Laserhawk: A Blood Dragon Remix | His eyes have seemingly been replaced by robotic prosthetics. | Glenn Wrage |
| 2023 | Marcus Holloway | Captain Laserhawk: A Blood Dragon Remix | Blindness in one eye. | Mark Ebulue |
| 2023 | Red | Captain Laserhawk: A Blood Dragon Remix | His left arm was replaced with a robotic prosthetic. | Adi Shankar |
| 2023 | Sam Fisher | Captain Laserhawk: A Blood Dragon Remix | He is a double leg amputee and uses a wheelchair. | Nigel Barber |

## Comics and manga

| First year | Character | Series/Franchise | Author/Publisher | Disability |
| 1964 | Daredevil | Daredevil | Marvel Comics | Blindness. |
| 1991 | Hotaru Tomoe (Sailor Saturn) | Sailor Moon | Naoko Takeuchi | Hotaru has mysterious seizures due to being the host of the Daimon Mistress 9. |
| 2001 | Izumi Curtis | Fullmetal Alchemist | Hiromu Arakawa | Izumi has a chronic illness due to missing organs. |
| 2001 | Edward Elric | Fullmetal Alchemist | Hiromu Arakawa | Edward is a double amputee. |
| 2001 | Kiyoharu Togawa, Tomomi Nomiya, and Hisanobu Takahashi | Real | Takehiko Inoue | Wheelchair-bound. |
| 1966 | Barbara Gordon | Detective Comics, Batman | DC Comics | Became paraplegic when shot in the 1988 graphic novel Batman: The Killing Joke. The character's paralysis has been the subject of much critical commentary for and against restoring her mobility. |
| 2004 | Celty Sturluson | Durarara!! | Ryohgo Narita | Mute and communicates with a personal digital assistant. |
| 2009 | Homestuck trolls | Homestuck | Andrew Hussie | Many protagonists have disabilities, mostly from battle. Notably, Tavros Nitram has lower-body paralysis, Meulin Leijon is deaf, Terezi Pyrope is blind and synesthesic, and Mituna Captor has brain damage. |
| 2004 | Johnny Joestar | JoJo's Bizarre Adventure | Hirohiko Araki | Paraplegic and wheelchair-bound after being shot in the back. |
| 1984 | Jericho | Teen Titans | DC Comics | Mute and communicates with American Sign Language. |
| 1963 | Professor X | X-Men | Marvel Comics | Wheelchair-bound. |
| 1963 | Dr Strange | Avengers, Defenders, Illuminati, Infinity Watch, Midnight Sons, New Avengers and The Order | Marvel Comics | Nerve damage in his hands that limits his ability to perform surgeries. Loss of fine motor control. |
| 1967 | Wilson Fisk AKA Kingpin | Daredevil | Marvel Comics | ASC Autistic Spectrum Condition |
| 1997 | Echo AKA Ronin | The New Avengers, Daredevil | Marvel Comics | Deaf |
| 1941 | The Penguin | Batman | DC Comics | Physical disability and difficulties with movement |
| 1981 | Stick | Daredevil | Marvel Comics | Blindness. |
| 1964 | Clint Barton AKA Hawkeye | Tales of Suspense, Avengers, Captain America and The New Avengers | Marvel Comics | Deafness. |
| 1963 | Nick Fury | Avengers | Marvel Comics | Vision impairment from losing an eye. |
| 1979 | James Rupert "Rhodey" Rhodes AKA War Machine | Avengers West Coast | Marvel Comics | Motor disability. He relies on mechanical leg bracesor a full body mech suit for mobility. |
| 1941 | Bucky Barnes AKA Winter Soldier | Captain America Comics | Marvel Comics | Limb difference, he's missing a hand. |
| 1942 | Freddy Freeman (Captain Marvel Jr) | Marvel/Shazam Family, Teen Titans, Outsiders, Young Justice and Justice League | Marvel Comics | Severe Motor disability but only when he is Freddy Freeman |
| 2008 | Agent Phil Coulson | S.H.I.E.L.D. | Marvel Comics | Limb difference from losing a hand and having a prosthetic one. |
| 1943 | Clifford DeVoe AKA Thinker | Justice Society of America | DC Comics | Wheelchair user. |
| 1980 | Victor Stone AKA Cyborg | Teen Titans, Justice League, S.T.A.R. Labs, Doom Patrol, Justice League Odyssey | Marvel Comics | Physical disability and cybernetic prosthetics |
| 1989 | Jubilation "Jubilee" Lee | New Warriors,X-Men, Generation X | Marvel Comics | Cognitive or learning disability |
| 1975 | Misty Knight | Daughters of the Dragon, Heroes for Hire, Defenders and Valkyrior | Marvel Comics | limb difference and a prosthetic bionic arm |
| 1962 | Odin | Avengers (1,000,000 BC) | Marvel Comics | Vision impaired and he has several body parts missing |
| 1963 | Dr. Curt Connors AKA Lizard | Spiderman | Marvel Comics | Limb difference. Lost his left arm and usually functions even without a prosthesis |
| 1943 | Barbara Minerva AKA Cheetah | Wonder Woman | DC Comics | Has mobility problems, uses a cane and suffers pain in her non-cheetah form. |
| 1959 | Victor Fries AKA Mr Freeze | Batman | DC Comics | He requires usage of assistive tech (his cryo-suit) to live and move |
| 1986 | Cable | he Uncanny X-Men and The New Mutants | Marvel Comics | He has a virus that is slowly eating away at his body, so more and more of him is preplaced with technology. |
| 1962 | Alecia Masters | The Fantastic Four | Marvel Comics | One of the most famous artists of the Marvel universe and is known as a brilliant sculptor. |
| 1980 | Madame Web | The Amazing Spider-Man | Marvel Comics | Blind and paralyzed. |
| 1963 | Cliff Steel AKA Robot Man | Doom Patrol and Justice League United | DC Comics | Entire body replaced with a prosthetic metal body. |
| 1963 | Dr. Niles Caulder AKA Chief | Doom Patrol and Justice League United | DC Comics | Wheelchair user. |
| 1941 | Dr. Charles McNider AKA Doctor Mid-Night | All-Star Squadron, U.S. Medical Corps, Black Lantern Corps, Justice League | DC Comics | Blind |
| 1981 | Caliban | X-Force, X-Men, The 198, Horsemen of Apocalypse, X-Factor, Morlocks | Marvel Comics | Abinism |
| 1981 | Rogue | X-Men, Brotherhood of Evil Mutants, Avengers Unity Division, X-Treme X-Men | Marvel Comics | Unable to touch anyone, so like someone with an extreme auto-immune condition, she has to live a physically isolated life. |
| 1963 | Cyclops | X-Men, X-Force, X-Factor, Phoenix Five, X-Corporation, Hounds, Starjammers | Marvel Comics | Extreme form of vision impairment. |
| 1992 | Cerise | Excalibur, Graces | Marvel Comics | Wheelchair user. |
| 1983 | Puck | Alpha Flight, Beta Flight, Gamma Flight and X-Force | Marvel Comics | Short stature. |
| 1979 | The Hornet | Slingers | Marvel Comics | Cerebral Palsy or Wheelchair user |
| 1966 | Oracle | Justice League, Birds of Prey, Batman Family, Seven Soldiers of Victory, Suicide Squad, Batman Incorporated,GCPD, Young Justice, Justice League United | Marvel Comics | Wheelchair user |
| 2007 | Komodo | The Initiative, Desert Stars, Shadow Initiative | Marvel Comics | Double amputee |
| 1983 | Box AKA Roger Boch | Alpha Flight, Beta Flight, Gamma Flight | Marvel Comics | Double amputee |
| 2013 | Anna Maria Marconi | Spiderman | Marvel Comics | Short stature. |
| 2012 | Nick Fury Jr | S.H.I.E.L.D., Secret Avengers, United States Army, 75th Ranger Regiment | Marvel Comics | Vision impaired with one eye. |
| 1963 | Flash Thompson / Agent Venom | United States Army, Project Rebirth, Secret Avengers, Thunderbolts, Guardians of the Galaxy, New Warriors, S.H.I.E.L.D., Agent of Cosmos | Marvel Comics | Flash Thompson, also known as Agent Venom, is a disabled veteran in the Marvel Universe. He uses a wheelchair |
| 1976 | Wendy Harris AKA Proxy | Super Friends, Teen Titans, Oracle, Batgirl, Space Canine Patrol Agents | DC Comics | Wheelchair user. |
| 1992 | Rose Wilson AKA Ravager | Teen Titans, Stormwatch, Defiance, N.O.W.H.E.R.E., League of Assassins, Terror Titans, Suicide Squad | DC Comics | Vision impaired with one eye. |
| 2006 | Amon Tomaz AKA Osiris | Teen Titans, Titans, Villains for Hire, Black Marvel Family, Black Lantern Corps, White Lantern Corps | DC Comics | Impaired movement and mobility in non-superpowered form |
| 1962 | Living Brain | Spiderman | Marvel Comics | His entire body is destroyed except for his brain, interacts through a moveable robot |
| 1995 | Gearhead | Secret Society of Super Villains, Batman | DC Comics | He has prosthetics that replaced his frostbitten alien limbs |
| 1968 | Grim Reaper | Batman | DC Comics | Limb differences and prosthetics |
| 1991 | Bishop | X-Treme Sanctions Executive, Xavier's Security Enforcers, X-Treme X-Men, The Twelve, Marauders, Interpol, O*N*E, X-Men, NYPD | Marvel Comics | He has a bionic right arm. |
| 2003 | Aaron Cash | Batman | DC Comics | His missing hand has been replaced with a hook. |
| 2000 | Karima Shapandar | Acolytes, Marauders, X-Men, Genoshan Excalibur, Omega Prime Sentinels, Indian Police Force, Orchis | Marvel Comics | Multiple prosthetic implants and augmentations for missing body parts. |
| 1941 | Roy Harper AKA Arsenal | Teen Titans, Justice League, Seven Soldiers of Victory, Young Justice, Suicide Squad, Checkmate, Outsiders, The Outlaws | DC Comics | Has a bionic arm. |
| 1990 | Silhouette | Secret Avengers (Civil War), Folding Circle, New Warriors | Marvel Comics | Partially paralysed with impaired mobility. |
| 1980 | Irene Adler AKA Destiny | Brotherhood of Mutants, Freedom Force, HYDRA, Project: Black Womb, Quiet Council of Krakoa | Marvel Comics | Blindness |
| 1985 | Quincy McIver AKA Bushmaster | Thunderbolts, Serpent Society | Marvel Comics | Quadriplegic |
| 1980 | Karma | X-Men, Xavier Institute, New Mutants, Hellions, Utopians | Marvel Comics | Limb difference and prosthetics |
| 2012 | Death Locket | Babysitters Club, Young Masters, Avengers Undercover (Formerly) | Marvel Comics | Multiple prosthetic implants including a bionic arm. |

## Video games

| First year | Character(s) | Actor(s) | Game/Series | Disability |
| 1990 | Big Boss | David Hayter and Akio Otsuka, among others | Metal Gear | Has a missing eye and wears an eyepatch |
| 1993 | Jax | Ed Boon, among others | Mortal Kombat | Has two bionic prosthetic arms |
| 1997 | Barret Wallace | Beau Billingslea and Masahiro Kobayashi, among others | Final Fantasy VII | Has a missing hand replaced with a gatling gun called a "Gimmick Arm" |
| 1998 | Revolver Ocelot | Patric Zimmerman and Kōji Totani, among others | Metal Gear | Had a missing arm replaced with a transplant from Liquid Snake |
| 2000 | Alice Liddell | Susie Brann | American McGee's Alice and Alice: Madness Returns | Psychosis |
| 2001 | Raiden | Quinton Flynn and Kenyu Horiuchi | Metal Gear | Had much of his body destroyed and replaced with cybernetics |
| 2002 | Kenshi Takahashi | Noah Fleder | Mortal Kombat | Blindness |
| 2005 | Goro Majima | Hidenari Ugaki, Mark Hamill, and Matthew Mercer | Yakuza | Has a missing eye and wears an eyepatch |
| 2007 | Jeff "Joker" Moreau | Seth Green | Mass Effect | Brittle bone disease |
| 2008 | Nero | Johnny Yong Bosch and Kaito Ishikawa | Devil May Cry | Has a prosthetic arm called the Devil Bringer |
| 2012 | Clementine | Melissa Hutchison | The Walking Dead | Has an amputated leg |
| 2012 | Sir Hammerlock | J. Michael Tatum | Borderlands 2 | Amputee |
| 2012 | Nagito Komaeda | Megumi Ogata | Danganronpa | During Danganronpa 2: Goodbye Despair, he claims to have been diagnosed with frontotemporal dementia. In Danganronpa 3: The End of Hope's Peak High School, he is seen with a prosthetic hand that replaces the hand he sewed onto himself prior to the events of the anime. |
| 2012 | Taimi | Debi Derryberry | Guild Wars | Unspecified degenerative bone disorder |
| 2012 | Billie Lurk | Kristy Wu | Dishonored | Has a missing right eye and right arm. |
| 2013 | Zero | Tara Platt and Maaya Uchida | Drakengard 3 | Has a prosthetic arm |
| 2014 | Max Hass | Alex Solowitz | Wolfenstein | Severe brain damage since birth |
| 2014 | Dr. Krancase | Quinton Flynn | Skylanders: Trap Team | Has five (5) wooden, semi-mechanized prostethic legs. |
| 2015 | Venom Snake | Kiefer Sutherland | Metal Gear | Has a missing eye and arm, wears an eyepatch and prosthetic limb. |
| 2015 | Fran Bow | — | Fran Bow | Psychosis |
| 2016 | Cassidy | Matthew Mercer | Overwatch | Has a cybernetic prosthetic arm |
| 2016 | Symmetra | Anjali Bhimani | Overwatch | Has a cybernetic prosthetic arm |
| 2016 | Junkrat | Chris Parson | Overwatch | Has a prosthetic right leg |
| 2017 | Doomfist | Sahr Ngaujah | Overwatch | Has a cybernetic prosthetic arm |
| 2017 | Mae Borowski | Em Halberstadt | Night in the Woods | Depression, anxiety, dissociation |
| 2017 | Diogenes | — | Getting Over It with Bennett Foddy | Has no lower body mobility. |
| 2017 | Gregg Lee | — | Night in the Woods | Bipolar disorder |
| 2017 | Senua | Melina Juergens | Hellblade: Senua's Sacrifice | Severe psychosis |
| 2019 | Lena, the Cryptozoologist's wife | Tegen Hitchens | Disco Elysium | Paraplegia |
| 2020 | Sunny | — | Omori | They have Depression. |
| 2022 | Olivia | — | Fear & Hunger 2: Termina | Paraplegia |
| 2023 | Link | — | The Legend of Zelda: Tears of the Kingdom | Has an injured arm, replaced by a magical prosthesis. At the end of the game, the prothesis disappears. |

## Mascots

| Year | Character | Origin | Creator | Disability |
| 1992 | Petra | 1992 Summer Paralympics | Javier Mariscal | Missing arms |
| 1994 | Sondre | 1994 Winter Paralympics | Tor Lindrupsen and Janne Solem | Missing leg |
| 2024 | Paralympic Phryge | 2024 Summer Paralympics | Gilles Deleris | Missing leg, wears a prosthesis |
| 2026 | Milo | 2026 Winter Paralympics | Istituto Comprensivo Taverna | Missing leg |