OpenLLM-France/wikimedia huggingface dataset:
# Hepatitis C vaccine

A hepatitis C vaccine, a vaccine capable of protecting against the hepatitis C virus (HCV), is not yet available. Although vaccines exist for hepatitis A and hepatitis B, development of an HCV vaccine has presented challenges. No vaccine is currently available, but several vaccines are currently under development.
Most vaccines work through inducing an antibody response that targets the outer surfaces of viruses. However, the HCV virus is highly variable among strains and rapidly mutating, making an effective vaccine very difficult.
Another strategy which is different from a conventional vaccine is to induce the T cell arm of the immune response using viral vectors, adenoviral vectors that contain large parts of the HCV genome itself, to induce a T cell immune response against HCV. Most of the work to develop a T cell vaccine has been done against a particular genotype. There are six different genotypes which reflect differences in the structure of the virus. The first approved vaccine will likely only target genotypes 1a and 1b, which account for over 60% of chronic HCV infections worldwide. Likely, vaccines following the first approved vaccine will address other genotypes by prevalence.
VLP-based HCV vaccines are also subject of intensive research.
Since 2014, well-tolerated and extremely effective direct‐acting antiviral agents (DAAs) have been available which allows eradication of the disease in 8–12 weeks in most patients. While this has changed treatment options drastically for patients with HCV, it does not replace a vaccine that would prevent people from ever getting infected with the virus and will likely not be sufficient to eradicate HCV completely.

## Specific vaccines

As of 2020, Inovio Pharmaceuticals is developing a synthetic multi-antigen DNA vaccine covering HCV genotypes 1a and 1b and targeting the HCV antigens nonstructural protein 3 (NS3) and 4A (NS4A), as well as NS4B and NS5A proteins. Following immunization, rhesus macaques mounted strong HCV-specific T cell immune responses strikingly similar to those reported in patients who have cleared the virus on their own. The responses included strong HCV antigen-specific interferon-γ (IFN-γ), tumor necrosis factor-α (TNF-α), and interleukin-2 (IL-2) induction, robust CD4 and CD8 T cell proliferation, and induction of polyfunctional T cells. This vaccine is in Phase I clinical trial.
The major histocompatibility complex class II-associated invariant chain (CD74)—fused with a viral vector to a conserved region of the HCV genome—has been tested as an adjuvant for an HCV vaccine in a cohort of 17 healthy human volunteers. This experimental vaccine was well-tolerated, and those who received the adjuvanted vaccine had stronger anti-HCV immune responses (enhanced magnitude, breadth and proliferative capacity of anti-HCV-specific T helper cells) compared with volunteers who received the vaccine that lacked this adjuvant.
# Mansun Chan

Mansun Chan is an Alex Wong Siu Wah Gigi Wong Fook Chi Professor of Engineering and Chair Professor at the Department of Electronic & Computer Engineering, HKUST and Director of Nanoelectronics Fabrication Facility/Adjunct Professor, Peking University Shenzhen Graduate School. He was named Fellow of the Institute of Electrical and Electronics Engineers (IEEE) in 2013 for contributions to CMOS device modeling.

## Education

Chan obtained his BS degree in Electrical Engineering (highest honors) and BS degree in Computer Sciences (highest honors) in 1990 and 1991 respectively, both from University of California, San Diego. He then got his MS degree in 1994 and PhD degree in 1995 from the University of California, Berkeley.
# Ghost (Crack the Sky album)

Professional ratings :
| Review scores ||
| Source | Rating |
| Allmusic | link |
Ghost is an album by American progressive rock band Crack the Sky.

## Personnel
### The band

* John Palumbo – Lead vocals, guitar, synthesizer
* Rick Witkowski – Guitar
* Bobby Hird – Guitar
* Carey Ziegler – Bass guitar
* Tracey Worsman – Drums
* Glenn Workman – Keyboards, piano
# Vassobia

Vassobia is a genus of flowering plants belonging to the family Solanaceae.
Its native range is South America.
Species:
* Vassobia breviflora (Sendtn.) Hunz.
* Vassobia dichotoma (Rusby) Bitter
# Hemelsoet

Hemelsoet is a surname. Notable people with the surname include:
* Joseph Hemelsoet (1905–?), Belgian racing cyclist
* Maurice Hemelsoet (1875–1943), Belgian rower and Olympian
# Hadley Bourne

Hadley Bourne is a grade II listed building in Dury Road, Monken Hadley, England.
# La terre est ronde (disambiguation)

La terre est ronde is a French expression meaning "world is round".
It may refer to:
* "La terre est ronde", single by Orelsan from his 2011 album Le chant des sirènes
* La terre est ronde, 1937 play by Armand Salacrou
* Le terre est ronde, 1960 film by Philippe Ducrest
# Swimming at the 1991 Pan American Games – Men's 400 metre freestyle

The men's 400 metre freestyle competition of the swimming events at the 1991 Pan American Games took place on 16 August. The last Pan American Games champion was Paul Robinson of US.
This race consisted of eight lengths of the pool, with all eight being in the freestyle stroke.

## Results

All times are in minutes and seconds.
| KEY: | q | Fastest non-qualifiers | Q | Qualified | GR | Games record | NR | National record | PB | Personal best | SB | Seasonal best |

### Final

The final was held on August 16.
| Rank | Name | Nationality | Time | Notes |
| | Sean Killion | United States | 3:50.38 | GR |
| | Jorge Herrera | Puerto Rico | 3:54.91 | |
| | Eric Diehl | United States | 3:58.06 | |
| 4 | Pedro Carrío | Cuba | 3:59.60 | |
| 5 | Robbie McFarlane | Canada | 3:59.89 | |
| 6 | Gabriel Chaillou | Argentina | 4:02.40 | |
| 7 | Carlos Scanavino | Uruguay | 4:02.56 | |
| 8 | Sean Swain | Canada | 4:06.48 | |
# V – Part Three of L.O.V.E

V – Part Three of L.O.V.E is the third EP in Sofia Talvik's four album saga, and was released 2011. Along with three new songs, the album includes a new performance of Jonestown, the title song from her earlier album, Jonestown. Produced by Talvik's bass player, Janne Manninen, the EP contains an "electronica pop" feel, utilizing synthesizers more than previous projects.

## Track listing

All tracks are written by Sofia Talvik
# Arthur Zimek

Arthur Zimek is a professor in data mining, data science and machine learning at the University of Southern Denmark in Odense, Denmark.
He graduated from the Ludwig Maximilian University of Munich in Munich, Germany, where he worked with Prof. Hans-Peter Kriegel. His dissertation on "Correlation Clustering" was awarded the "SIGKDD Doctoral Dissertation Award 2009 Runner-up" by the Association for Computing Machinery.
He is well known for his work on outlier detection, density-based clustering, correlation clustering, and the curse of dimensionality.
He is one of the founders and core developers of the open-source ELKI data mining framework.
# Giacomo De Martino (governor)

Giacomo De Martino (21 September 1849 – 23 November 1921) was an Italian politician, who was governor in the Italian colonies.

## Biography

Born in London in 1849 from a rich Italian family. He was one of the main supporters of the Italian colonialism since he was young. Initially he was a diplomat, but soon started to do a political career. In 1905 he was elected at the Italian Senate. In 1906 De Martino created the Istituto coloniale italiano, in order to promote the development of the Italian colonies and their management.
Appointed senator (March 4, 1905), De Martino made long journeys to the Indies and to eastern and northern Africa and continued his propaganda with speeches and publications including the book Cyrene and Carthage (Bologna 1908). Appointed governor of Somalia (January 11, 1910), he began a policy of economic strengthening of that colony and of affirmation and expansion of Italian dominion, starting studies for the construction of a port, a road network and a railway towards the interior, making the first attempts at white colonization, establishing the regime of agricultural concessions on the Giuba and initiating the first contacts with the populations of the Oltre-Giuba. The dams of the Scebeli, the Genale dam and the relative state experimental company, and the purchase of Mahaddei-Uen on the Scebeli, Bur Acaba and Baidoa date back to him. As governor of the Colony of Eritrea (1916-1919), De Martino gave great impetus to public works, such as the construction of the customs sheds of Massawa, the building development of Asmara, the extension of the railway line in Cheren and beyond, towards the Gasc , the plants of the first mountain hydroelectric basin with the Belesa dam, and the industrial agricultural setting of Tessenei. On 1 July 1919, De Martino was sent to govern Cyrenaica. Treccani E.
He had held several colonial posts as he had been a governor of the Italian colonies of Somaliland (1910–1916), Eritrea (1916–1919), and finally Cyrenaica (1919–1921), where he had died at office of heart attack.
# Vaughan family

The Vaughan family is a Nigerian American family with branches on both sides of the Atlantic Ocean. In Nigeria, it has links to the Nigerian chieftaincy system and the Nigerian bourgeoisie, while in America, it belongs to the African-American upper class.

## Family history

The Vaughans claim descent from the union of Scipio Vaughan, an American freedman of royal Owu Egba origin, and Maria Theresa Conway, who was herself of Catawba descent. On Scipio's deathbed, he told his two sons Burrell Churchill Vaughan and James Churchill Vaughan Sr. to return to his ancestral home in Yorubaland following his death. The pair ultimately did so, and later established the Nigerian branch of the family before their own deaths. The American branch, meanwhile, was itself established by those of their siblings that remained behind.

## Nigerian lineage

Vaughan's Nigerian descendants include the nationalist Dr. James C. Vaughan Jr. and Nigerian women's rights activist Kofoworola, Lady Ademola.

## American lineage

Vaughan's American descendants include the U.S. government official Jewel Lafontant-Mankarious and her son, the businessman John W. Rogers Jr.

## Today

The Vaughan family, while being either Nigerian or American, has provided a large number of doctors, lawyers, businesspeople and politicians over the years of its existence.
The American branch started the incentive to trace its African heritage and re-unite with the African group of Vaughan descendants. Its members first attempt to convene a reunion started in August, 1970, when several Vaughans convened a meeting in Pittsburgh and decided to arrange an annual reunion of all their known relatives. They read the research of a deceased family member, Aida Arabella Stradford, a South Carolina school teacher, and studied census figures, family Bible records and other documents. Today, the American Vaughans are a network of more than 3,000 cousins from over 22 states. From the daughters, who remained in the United States, the cousins have traced the eight main family lines - Barnes, Brevard, Bufford, Cauthen, McGriff, Peay, Truesdale and Vaughan.
The Nigerian branch, for its part, was involved in major events back in the family's homeland: it took part in colonial politics, was active in the women's movement in the Independence era, and intermarried with various Nigerian royal families. Prominent lines amongst the Nigerian Vaughans include Vaughan, Coker, Moore and Vaughan-Richards. The Nigerian Vaughans and their American relatives have stayed in touch through the years after James Churchill Vaughan Sr.'s death, and today the Nigerians take part in the periodic "Cousin" reunions in America.
They may also have descendants in Jamaica.

## Gallery

* Kofoworola, Lady Ademola, a member of the Nigerian branch
* John W. Rogers, Jr., a member of the American branch
# Hemihydranencephaly

Hemihydranencephaly is a severe cephalic disorder characterized by complete or almost complete absence of one hemisphere of the cerebral cortex with preservation of meninges, basal ganglia, pons, medulla, cerebellum, and falx. It is a special type of hydranencephaly.
It is a very rare disease. As it stands, only 9 cases have been reported. Cognitive and language functions may be largely or totally normal, although motor function deficits in one half of the body are typical.
# Halimi Family Order of Kedah

The Most Illustrious Halimi Family Order of Kedah (Bahasa Melayu: Darjah Kerabat Halimi Yang Amat Mulia Kedah) is an honorific order of the Sultanate of Kedah

## History

It was founded by Sultan 'Abdu'l Halim Mu'azzam Shah of Kedah in January 1973.

## Award conditions

The Darjah Kerabat Halimi is conferred at the express wish of the Sultan and is reserved for members of the Royal Family only.

## Classes

It is awarded in one class:
* Darjah Kerabat Halimi or member - DKH

## Insignia

The men's insignia consist of a sash, a neck chain and a star (Photo). The women's insignia consist of a chest knot, a neck chain and a star (Photo).

## Notable recipients

Sultan Abdul Halim of Kedah:
* Founding Grand Master and Member of the Halimi Family Order of Kedah (DKH, since January 1973)
Members of the Royal Family of Kedah :
* Member of the Halimi Family Order of Kedah :
** late Tuanku Bahiyah DMN SMN DK DKH SPMK (1st wife of the Sultan Abdul Halim) (DKH, 1.1976)
** Sultanah Haminah of Kedah DMN DK DKH (current wife of the Sultan) (DKH, 16.7.2008)
** Princess Intan Safinaz PSM DKH SSDK SHMS JP PAT (Sultan Abdul Halim of Kedah and Tuanku Bahiyah's daughter and Mbr of the Regency Council 2011) (DKH, 16.7.2008)
** Tunku Abdul Malik, Raja Muda DK DKH DMK SPMK PSB (1st younger brother of the Sultan and heir prince of Kedah) (DKH, 22.2.1976)
** Tunku Annuar, Tunku Bendahara PSM DKH DMK SPMK SSDK PSB (2nd ygr br. of the Sultan and head of the Regency Council 2011) (DKH, 16.7.2008)

### Lists of recipients

* List of honours of the Kedah Royal Family by country
* List of Honours of Kedah awarded to Heads of State and Royals
* Category: Members of the Halimi Family Order of Kedah
# James D. Blankenbecler

James D. Blankenbecler (June 27, 1963 – October 1, 2003) was an American command sergeant major and the highest-ranking enlisted soldier to be killed by hostile fire in the Iraq War.

## Early life and education

Blankenbecler was born on June 27, 1963, in Arlington County, Virginia. Blankenbecler grew up in Northern Virginia and attended Groveton High School (now West Potomac High School).

## Military career

Blankenbecler joined the United States Army in 1983 and served during the Gulf War and at Fort Belvoir.
In 2003, Blankenbecler was assigned to the 1st Battalion, 44th Air Defense Artillery Regiment at Fort Hood, Texas and deployed to Iraq.

## Death and legacy

Blankenbecler died on October 1, 2003, in Samarra, Iraq, due to injuries sustained after being in convoy that was "hit by an improvised explosive device and rocket-propelled grenades".
In 2005, a bill was passed by the Virginia General Assembly to honor Blankenbecler.
In 2014, the CSM James D. Blankenbecler Resilience Center was opened and dedicated in Blankenbecler's name.
In 2018, West Potomac High School held a Veteran's Day of Service to honor Blankenbecler.
# Vilmos Wilheim

Vilmos Wilheim (25 November 1895 – 1962) was a Hungarian football manager and former player.

## Club career

Born in Hungarian capital Budapest, Wilheim played with KAOE before joining Ferencváros in 1916 and playing with them in the Hungarian championship since 1917. Later, he played in Italy with Vicenza (1923–24) and Cremonese (seasons 1925–26 and 1026–27). He made 15 appearances and scored 2 goals in the 1926–27 Divisione Nazionale.

## Coaching career

After retiring, Wilheim started his coaching career. Between 1928 and 1939 he coached in Italy the following clubs: Vicenza, Spezia, Foggia and Padova. Then he moved to Yugoslavia, coaching Bosnian side FK Slavija in their campaign in the 1939–40 Yugoslav Football Championship. In the late 1940s he returned to Italy and coached for second time Padova and Vicenza.
He was known in Italy also as Wilmas Wilhelm or Guglielmo Wilhelm.
# Swimming at the 1991 Pan American Games – Men's 200 metre breaststroke

The men's 200 metre breaststroke competition of the swimming events at the 1991 Pan American Games took place on 16 August. The last Pan American Games champion was Jeff Kubiak of US.
This race consisted of four lengths of the pool, all in breaststroke.

## Results

All times are in minutes and seconds.
| KEY: | q | Fastest non-qualifiers | Q | Qualified | GR | Games record | NR | National record | PB | Personal best | SB | Seasonal best |

### Final

The final was held on August 16.
| Rank | Name | Nationality | Time | Notes |
| | Mario González | Cuba | 2:15.50 | GR |
| | Nelson Diebel | United States | 2:16.08 | |
| | Tyler Mayfield | United States | 2:17.49 | |
| 4 | Pablo Minelli | Argentina | 2:17.96 | |
| 5 | Robert Fox | Canada | 2:19.01 | |
| 6 | Gustavo Gorriaran | Uruguay | 2:20.38 | |
| 7 | Andrew Tussler | Canada | 2:20.55 | |
| 8 | Jaime Mitropoulos | Brazil | 2:22.36 | |
# Blood Promise

Blood Promise may refer to:
* Blood Promise (novel), a novel by Richelle Mead
* Blood Promise (film), a film made in Hong Kong in 1975
* A Blood Promise, a DVD/CD recorded by the band Her Name Is Calla
# Lagocephalus spadiceus

Lagocephalus spadiceus, also known as the half-smooth golden pufferfish, is a species of fish in the family Tetraodontidae. It is a common fish in the Red Sea, as well as the Indian Ocean, but can be found also in the Mediterranean, where it arrived from its natural habitat by Lessepsian migration.
Consumption of this fish can be deadly. Its internal organs, such as liver, gall bladder and sexual organs, contain tetrodotoxin, a powerful neurotoxin.
# Velurpalaiyam plates

The Velurpalaiyam plates of Nandivarman III is a 9th-century copper-plate grant which was found at the village of Velurpalaiyam, around 7 miles from the town of Arakkonam in Tamil Nadu, India. The grant records the gift of a village to a temple of Shiva by the Pallava king, Nandivarman III (r. 846–869). The inscriptions on the plates are in Tamil and partly in Sanskrit (employing the Grantha script) and additionally provide a valuable genealogical record of the Pallavas.
# United States House Intelligence Subcommittee on National Intelligence Enterprise

The House Intelligence Subcommittee on Counterterrorism, Counterintelligence and Counterproliferation is one of the four subcommittees within the Permanent Select Committee on Intelligence through the 117th United States Congress. It is sometimes referred to as the "C3" subcommittee as a nickname.
Prior to the 116th Congress, it was known as the Subcommittee on Emerging Threats.

## Members, 117th Congress

| Majority | Minority |
| André Carson, Indiana, Chair Jackie Speier, California Mike Quigley, Illinois Joaquin Castro, Texas Peter Welch, Vermont Sean Patrick Maloney, New York | Rick Crawford, Arkansas, Ranking Member Brad Wenstrup, Ohio Chris Stewart, Utah TBD |
| Ex officio ||
| Adam Schiff, California | Devin Nunes, California |
# LMP1

LMP1 may refer to:
* Epstein–Barr virus latent membrane protein 1
* Le Mans Prototype, a type of sports prototype race car
* GMS Durango LMP1, a Le Mans Prototype built for Durango by GMS in 2000
* Panoz LMP-1 Roadster-S, a Le Mans Prototype built for Panoz in 1999
# IFAR

IFAR may refer to one of the following
* Ifar Gunung in Papua
* International Fanconi Anemia Registry
* International Forum for Aviation Research
* International Foundation for Art Research
* In-Flight Aspect Ratio in Fusion Science Research
# VEG

VEG may refer to:
* Covenant of Free Evangelical Congregations in the Netherlands, a Reformed denomination in the Netherlands
* Geisenheim Alumni Association, an alumni network in Germany
* Volkseigenes Gut, a state-owned farm in the German Democratic Republic
* .veg, file extension for projects in Vegas Pro
# Frits Kemp

Frits Kemp (born February 26, 1954) is a Dutch attorney, receiver and activist. Kemp has been a lawyer since 1988 and founded the law firm, FORT in 2001 together with three other partners. On December the 4, 2014 Kemp gained national attention after becoming the receiver of Dutch fashion brand Mexx declaring its 315 stores bankrupt.
Kemp is a member of the activist group 1Overheid, A team of experts in law and finance aiming to prevent fraud in the Netherlands.
# Vendore

Vendore is situated in Amballur village in the Thrissur district of Kerala, India. Vendore is situated in between Amballur and Mannampetta. Vendore comes under AlagappaNagar GramaPanchayat and the nearest town is Amballur, about 2 km away. The football ground 'Alagappanagar Football Ground' is in Vendore. Vendore is also famous for St Mary's Church and Nambooriyachan Temple . One of the old known mills, Alagappanagar Textile Mill, is also located here. The Panchayath office is located in Vendore nearer to the Veterinary Hospital.

## History

The name Vendore came from the group of peoples who came and settled from Kodungallur due to Tippu Battle years ago. Since they were doing trade of Manjal others started calling them Manjaly.

## Educational institutions

* Thiagarajar Polytechnic College, Alagappanagar
* St. Francis Xavier LP School
* St. Mary's LKG and UKG
* Alagappanagar High School
# United States House Intelligence Subcommittee on National Security Agency and Cyber

The House Intelligence Subcommittee on Strategic Technologies and Advanced Research is one of the four subcommittees within the Permanent Select Committee on Intelligence. It is sometimes referred to by its nickname, the "STAR" subcommittee.
Prior to the 116th Congress, it was known as the Subcommittee on the NSA and Cybersecurity.

## Members, 117th Congress

| Majority | Minority |
| Jim Himes, Connecticut, Chair Andre Carson, Indiana Mike Quigley, Illinois Eric Swalwell, California Andre Carson, Indiana Raja Krishnamoorthi, Illinois TBD | TBD |
| Ex officio ||
| Adam Schiff, California | Devin Nunes, California |