# List of The Big Bang Theory guest stars

This is a list of The Big Bang Theory guest stars. Most "played" themselves. The episodes in which they appeared are followed by the season in brackets.

## Actors

* Sean Astin as Dr. Greg Pemberton
** "The Confirmation Polarization" (12)
** "The Laureate Accumulation" (12)
** "The Plagiarism Schism" (12)
* Kathy Bates as Mrs. Fowler, Amy Farrah Fowler's mother
** "The Bow Tie Asymmetry" (11)
** "The Conjugal Configuration" (12)
** "The Consummation Deviation" (12)
* LeVar Burton
** "The Toast Derivation" (4)
** "The Habitation Configuration" (6)
** "The Champagne Reflection" (8)
* Keith Carradine as Wyatt, Penny's father
** "The Boyfriend Complexity" (4)
** "The Bachelor Party Corrosion" (9)
** "The Conjugal Conjecture" (10)
** "The Procreation Calculation" (12)
** "The Donation Oscillation" (12)
* Eliza Dushku as FBI Special Agent Angela Page
** "The Apology Insufficiency" (4)
* Nathan Fillion
** "The Comic Book Store Regeneration" (8)
* Carrie Fisher
** "The Convention Conundrum" (7)
* Sarah Michelle Gellar
** "The Stockholm Syndrome" (12)
* Summer Glau
** "The Terminator Decoupling" (2)
* Judy Greer as Dr. Elizabeth Plimpton
** "The Plimpton Stimulation" (3)
* Mark Hamill
** "The Bow Tie Asymmetry" (11)
* Courtney Henggeler as Missy, Sheldon's sister
** "The Pork Chop Indeterminacy" (1)
** "The Bow Tie Asymmetry" (11)
* James Earl Jones
** "The Convention Conundrum" (7)
* Christopher Lloyd as Theodore, to whom Sheldon sublets his room
** "The Property Division Collision" (10)
* Joe Manganiello
** "The D&D Vortex" (12)
* Danica McKellar as Abby
** "The Psychic Vortex" (3)
* Leonard Nimoy
** "The Transporter Malfunction" (5, voice)
* Jerry O'Connell as George Cooper Jr., Sheldon's older brother
** "The Sibling Realignment" (11)
** "The Bow Tie Asymmetry" (11)
** "The Tam Turbulence" (12)
* Jodi Lyn O'Keefe as Mikayla, a prostitute
** "The Vegas Renormalization" (2)
* Kal Penn as Dr. Kevin Campbell
** "The Confirmation Polarization" (12)
** "The Laureate Accumulation" (12)
** "The Plagiarism Schism" (12)
* Katee Sackhoff
** "The Vengeance Formulation" (3)
** "The Hot Troll Deviation" (4)
* Charlie Sheen
** "The Griffin Equivalency" (2)
* William Shatner
** "The D&D Vortex" (12)
* Kevin Smith
** "The Fortification Implementation" (8)
** "The D&D Vortex" (12)
* Octavia Spencer as a Department of Motor Vehicles employee
** "The Euclid Alternative" (2)
* Brent Spiner
** "The Russian Rocket Reaction" (5)
* June Squibb as Meemaw, Sheldon's grandmother
** "The Meemaw Materialization" (9)
* George Takei
** "The Hot Troll Deviation" (4)
* Billy Bob Thornton as Dr. Oliver Lorvis
** "The Misinterpretation Agitation" (8)
* Analeigh Tipton
** "The Panty Piñata Polarization" (2)
** “The Mystery Date Observation” (9)
* Jessica Walter as Mrs. Latham, a philanthropist
** "The Benefactor Factor" (4)
* Adam West
** "The Celebration Experimentation" (9)
* Steven Yeun
** "The Staircase Implementation" (3)

## Athletes

* Kareem Abdul-Jabbar
** "The D&D Vortex" (12)
* Rick Fox as Glenn, Bernadette's ex-boyfriend
** "The Love Car Displacement" (4)

## Astronauts

* Buzz Aldrin
** "The Holographic Excitation" (6)
* Mike Massimino
** "The Friendship Contraction" (5)
** "The Countdown Reflection" (5)
** "The Decoupling Fluctuation" (6)
** "The Re-Entry Minimization" (6)
** "The Table Polarization" (7)
** "The First Pitch Insufficiency" (8)

## Comedians

* Eric André as Joey
** "The 21-Second Excitation" (4)
* Lewis Black as Professor Crawley
** "The Jiminy Conjecture" (3)
* Ellen DeGeneres
** "The Geology Elevation" (10)
** "The Laureate Accumulation" (12)
* Howie Mandel
** "The Re-entry Minimization" (6)
* Stephen Merchant as Dave Gibbs
** "The Spock Resonance" (9)
** "The Mystery Date Observation" (9)
** "The Earworm Reverberation" (9)
* Michael Rapaport as Kenny Fitzgerald
** "The Helium Insufficiency" (9)
* Bob Newhart as Arthur Jeffries, "Professor Proton"
** "The Proton Resurgence" (6)
** "The Proton Displacement" (7)
** "The Proton Transmogrification" (7)
** "The Opening Night Excitation" (9)
** "The Proton Regeneration" (11)
** "The Planetarium Collision" (12)
* Teller as Mr. Fowler, Amy Farrah Fowler's father
** "The Bow Tie Asymmetry" (11)
** "The Conjugal Configuration" (12)
** "The Consummation Deviation" (12)

## Entrepreneurs

* Bill Gates
** "The Gates Excitation" (11)
* Elon Musk
** "The Platonic Permutation" (9)
* Steve Wozniak
** "The Cruciferous Vegetable Amplification" (4)

## Scientists

* Frances Arnold
** "The Laureate Accumulation" (12)
* Brian Greene
** "The Herb Garden Germination" (4)
* Stephen Hawking
** "The Hawking Excitation" (5)
** "The Extract Obliteration" (6, voice)
** "The Relationship Diremption" (7, voice)
** "The Troll Manifestation" (8)
** "The Celebration Experimentation" (9)
** "The Geology Elevation" (10)
** "The Proposal Proposal" (11)
* George Smoot
** "The Laureate Accumulation" (12)
* Kip Thorne
** "The Laureate Accumulation" (12)
* Neil deGrasse Tyson
** "The Apology Insufficiency" (4)
** "The Conjugal Configuration" (12)

## Others

* Ira Flatow
** "The Vengeance Formulation" (3, voice)
** "The Discovery Dissipation" (7)
** "The Retraction Reaction" (11)
* Neil Gaiman
** "The Comet Polarization" (11)
* Stan Lee
** "The Excelsior Acquisition" (3)
* Adam Nimoy
** "The Spock Resonance" (9)
* Bill Nye
** "The Proton Displacement" (7)
** "The Conjugal Configuration" (12)