# List of Roman Catholic churches in the Diocese of Charleston

This is a list of the Roman Catholic churches in the Diocese of Charleston, which encompasses the entire State of South Carolina in the United States. It does not include mission churches.
| Parish est. | Church name | Location | Current building | Description/sources |
| 1790 to 1850 ||||||
| 1791 | St. Mary of the Annunciation | Charleston | 1806 | The first Catholic church in the Carolinas |
| 1821 | Minor Basilica of St. Peter | Columbia | 1824 | The first Catholic church in Columbia. |
| 1821 | Cathedral of St. John the Baptist | Charleston | 1868 | Cathedral for the Diocese of Charleston. |
| 1837 | St. Patrick | Charleston | 1899 | |
| 1839 | St. Anne and St. Jude Parish | Sumpter | 2023 | |
| 1842 | St. Peter | Cheraw | | |
| 1845 | Stella Maris | Sullivan's Island | | |
| 1846 | St. Peter | Beaufort | | |
| 1850 to 1900 ||||||
| 1852 | St. Mary | Greenville | 1954 | |
| 1853 | St. Mary Help of Christians | Aiken | 1905 | |
| 1854 | St. Joseph | Chester | | |
| 1856 | St. Mary of the Immaculate Conception | Edgefield | 1860 | |
| 1861 | St. Joseph | Charleston | 1861 | Established as church for Irish immigrants |
| 1868 | St. Joseph | Anderson | 1988 | |
| 1884 | St. Paul the Apostle | Spartanburg | | |
| 1889 | St. Mary, Our Lady of Ransom | Georgetown | | |
| 1895 | St. William | Ward | | |
| 1898 | St. John the Beloved | Summerville | | |
| 1900 to 1940 ||||||
| 1911 | St. Mary | Yonges Island | | |
| 1914 | Our Lady of Perpetual Help | Camden | 1914 | |
| 1917 | Holy Trinity | Orangeburg | 1982 | |
| 1919 | St. Anne | Rock Hill | 1998 | |
| 1920 | Sacred Heart | Charleston | 1939 | |
| 1929 | St. John | North Charleston | | |
| 1935 | St. Andrew | Clemson | 1935 | |
| 1935 | St. Martin de Porres | Columbia | | |
| 1938 | Divine Saviour | York | | |
| 1939 | St. Anthony of Padua | Greenville | 1956 | |
| 1939 | St. Louis | Dillon | | |
| 1940 to 1950 ||||||
| 1940 | St. Andrew | Clemson | | |
| 1941 | St. Mary the Virgin Mother | Hartsville | 1940 | |
| 1943 | St. Mary of the Angels | Anderson | 1951 | |
| 1944 | Blessed Sacrament | Charleston | 1962 | |
| 1945 | St. James the Younger | Conway | 1961 | |
| 1945 | St. Mary | Rock Hill | 2006 | |
| 1945 | Our Lady of Lourdes | Greenville | 2004 | |
| 1946 | St. Andrew | Myrtle Beach | | |
| 1948 | St. Catherine of Siena | Lancaster | 1948 | |
| 1948 | St. Joseph | Columbia | | |
| 1949 | Our Lady of Peace | North Augusta | | |
| 1949 | St. Boniface | Joanna | | |
| 1949 | St. Joseph | Columbia | | |
| 1950 to 1970 ||||||
| 1952 | Our Lady of the Rosary | Greenville | | |
| 1952 | St. Philip the Apostle | Lake City | | |
| 1952 | St. Theresa | Winnsboro | | |
| 1953 | St. Thomas More | Columbia | | Located at the University of South Carolina |
| 1956 | Divine Redemer | Hanahan | | |
| 1956 | St. Mark | Newberrry | | |
| 1959 | Nativity | Chaleston | | |
| 1959 | St. John of the Cross | Batesville-Leesville | | |
| 1960 | St. Gregory the Great | Bluffton | 2000 | |
| 1963 | St. Anthony | Ridgeland | | |
| 1965 | Holy Cross | Pickens | | |
| 1965 | St. Peter Benizi | Moncks Corner | | |
| 1964 | Our Lady Star of the Sea | North Myrtle Beach | | |
| 1964 | Good Shepherd | McCormick | | |
| 1964 | St. Edward | Murphy's Village | | Originally established as parish for Irish Travelers. |
| 1966 | St. Thomas the Apostle | North Charleston | 1968 | |
| 1967 | Holy Spirit | Johns Island | 2004 | |
| 1967 | St. Augustine | Union | | |
| 1970 to 2000 ||||||
| 1972 | St. Elizabeth Ann Seton | Simpsonville | | |
| 1972 | Our Lady of the Hills | Columbia | | |
| 1973 | Christ Our King | Mount Pleasant | 1979 | |
| 1973 | Holy Family | Hilton Head Island | 1988 | |
| 1975 | St. Michael the Archangel | Murrells Inlet | | |
| 1976 | Immaculate Conception | Goose Creek | | |
| 1976 | Prince of Peace | Taylors | | |
| 1977 | St. John Neumann | Columbia | 1978 | |
| 1978 | Our Lady of the Lake | Chapin | | |
| 1979 | Corpus Christi | Lexington | 1980 | |
| 1979 | Jesus Our Risen Saviour | Spartanburg | 1987 | |
| 1979 | St. Gerald | Aiken | 1962 | |
| 1981 | Sacred Heart | Gaffney | 1955 | |
| 1983 | All Saints | Lake Wylie | 2006 | |
| 1984 | St. Francis by the Sea | Hilton Head Island | 1991 | |
| 1984 | St. Theresa the Little Flower | Summerville | 2011 | |
| 1985 | Blessed Trinity | Greer | 1985 | |
| 1985 | Precious Blood of Christ | Pawleys Island | | |
| 1989 | St. Mary Magdalene | Simpsonville | | |
| 1993 | St. Philip Neri | Fort Mill | 2013 | |
| 1994 | St. Paul the Apostle | Seneca | | |
| 1998 | Transfiguration | Blythewood | 2004 | |
| 1999 | St. Benedict | Mount Pleasant | 2010 | |
| 2000 to present ||||||
| 2002 | St. Mary Our Lady of Hope | Manning | 2003 | |
| 2004 | St. Ann | Santee | 2005 | |
| 2006 | Our Lady of Good Counsel | Folly Beach | 1950 | |
| 2007 | St. Ann | Kingstree | | |
| 2013 | Our Lady of Grace | Lancaster | 2016 | |
| 2012 | St. Clare of Asissi | Daniel Island | | |
| 2015 | Our Lady of La Vang | Greer | | |