# Desus & Mero (2019 TV series)

Desus & Mero is an American television late-night talk show hosted by comedians Desus Nice and The Kid Mero. The show aired from February 2019 to June 2022 on the premium cable and streaming service Showtime.

## History

Desus & Mero is the third series co-hosted by the pair, following the 2014 Complex TV web series Desus vs. Mero, and the 2016 Viceland television and web series Desus & Mero.

## Production
### Development

In June 2018, Showtime announced they had ordered a half-hour late night series starring Desus and Mero, to be the network's first late night show ever. Desus and Mero stated that the increased budget would allow the show to have more pre-recorded sketches, a research team, and an upgraded set. They also hired a writer's room with the following writers: Mike Pielocik, Josh Gondelman, Claire Friedman, Ziwe Fumudoh, Robert Kornhauser, and Heben Nigatu.

### Release

The series debuted February 21, 2019. Congresswoman Alexandria Ocasio-Cortez was their first guest. On April 21, 2019, it was announced that Desus & Mero would expand to air two nights per week, on Mondays and Thursdays. On November 21, 2019, the same day as the airing of season one's final episode, Showtime announced the renewal of the show for a second season.
Due to the COVID-19 pandemic, the show went on temporary hiatus, but returned on March 30 in a teleconferencing format from Baker and Martinez's respective homes. In September 2020, the show's Twitter announced that the show had been renewed for a third season, which set to premiere on January 31, 2021.
In August 2021, Showtime renewed the series for a fourth season.

### Cancellation

On July 18, 2022, Showtime confirmed that the show had concluded with its June 23 episode, as the two co-hosts had decided to pursue "separate creative endeavors moving forward".
The move was a surprise to many fans, though some took the news as confirmation of a suspected dispute between the hosts. There were rumors of a behind-the-scenes conflict surrounding the pair's longtime manager, Victor Lopez. Sources alleged that Showtime barred Lopez from attending meetings or tapings of the show after multiple formal complaints of abusive conduct. Baker reportedly supported the decision, while Martinez felt that Lopez deserved their support.
Martinez denied that there was any conflict and described the decision as "a strategy and one that we all agreed on." However, Martinez had also liked posts attributing the split to a rift over Lopez on Twitter.

## Episodes

| Season | Episodes | Episodes | Originally released | Originally released |
| Season | Episodes | Episodes | First released | Last released |
| 1 | 45 | 45 | February 21, 2019 (2019-02-21) | November 21, 2019 (2019-11-21) |
| 2 | 62 | 62 | February 3, 2020 (2020-02-03) | December 13, 2020 (2020-12-13) |
| 3 | 58 | 58 | January 31, 2021 (2021-01-31) | December 16, 2021 (2021-12-16) |
| 4 | 15 | 15 | March 10, 2022 (2022-03-10) | June 23, 2022 (2022-06-23) |

### Season 1 (2019)

| No. overall | No. in season | Title | Illustrious Guest(s) | Original release date | Viewers (millions) |
| 1 | 1 | "Series Premiere, Ballbags" | Alexandria Ocasio-Cortez | February 21, 2019 (2019-02-21) | 0.151 |
| 2 | 2 | "Talk Your Talk" | Don Cheadle | February 28, 2019 (2019-02-28) | N/A |
| 3 | 3 | "Struggle Jeans" | Vince Staples and John Legend | March 7, 2019 (2019-03-07) | 0.056 |
| 4 | 4 | "If I Woulda Did It" | Ben Stiller and 2 Chainz | March 14, 2019 (2019-03-14) | 0.032 |
| 5 | 5 | "Hateful Hairline" | Lupita Nyong'o, Winston Duke and Kirsten Gillibrand | March 21, 2019 (2019-03-21) | 0.052 |
| 6 | 6 | "You Thought!" | Carmelo Anthony and Jordan Peele | March 28, 2019 (2019-03-28) | N/A |
| 7 | 7 | "Mad Buns" | Issa Rae | April 4, 2019 (2019-04-04) | 0.030 |
| 8 | 8 | "News Adjacent" | Stacey Abrams and Anna Kendrick | April 11, 2019 (2019-04-11) | 0.078 |
| 9 | 9 | "Grits Ratio" | Cory Booker | April 18, 2019 (2019-04-18) | N/A |
| 10 | 10 | "Waiting For Julio" | Seth Rogen | May 2, 2019 (2019-05-02) | N/A |
| 11 | 11 | "On Deckington" | Lil Nas X | May 6, 2019 (2019-05-06) | 0.041 |
| 12 | 12 | "Open Your Third Eye" | Charlize Theron | May 9, 2019 (2019-05-09) | 0.029 |
| 13 | 13 | "Look At Your Mans" | Wu-Tang Clan | May 13, 2019 (2019-05-13) | 0.043 |
| 14 | 14 | "Fax" | Bill Hader | May 16, 2019 (2019-05-16) | N/A |
| 15 | 15 | "Jamaican Hockey" | Amy Poehler | May 20, 2019 (2019-05-20) | 0.020 |
| 16 | 16 | "Royal Baby Newport" | Gabrielle Union | May 23, 2019 (2019-05-23) | 0.038 |
| 17 | 17 | "Hold That" | Ava DuVernay | May 30, 2019 (2019-05-30) | N/A |
| 18 | 18 | "Lowkey, Stay Down" | Spike Lee | June 3, 2019 (2019-06-03) | N/A |
| 19 | 19 | "Platinum Dad Joke" | Pete Buttigieg | June 6, 2019 (2019-06-06) | N/A |
| 20 | 20 | "Pon'delocke" | Lin-Manuel Miranda | June 10, 2019 (2019-06-10) | N/A |
| 21 | 21 | "Electric Lemonade" | Regina Hall | June 13, 2019 (2019-06-13) | N/A |
| 22 | 22 | "It's Cultural" | ScHoolboy Q | June 17, 2019 (2019-06-17) | N/A |
| 23 | 23 | "Pivot to Alians" | Anthony Anderson | June 20, 2019 (2019-06-20) | N/A |
| 24 | 24 | "Y'All Not Low" | O'Shea Jackson | June 24, 2019 (2019-06-24) | N/A |
| 25 | 25 | "Link in Bio" | Zendaya | June 27, 2019 (2019-06-27) | N/A |
| 26 | 26 | "Bonus Illustriousness" | N/A | July 8, 2019 (2019-07-08) | N/A |
| 27 | 27 | "The Macaroni and Cheese Sound" | Kumail Nanjiani | July 11, 2019 (2019-07-11) | N/A |
| 28 | 28 | "Charcoonery Plate" | Kemba Walker | July 15, 2019 (2019-07-15) | N/A |
| 29 | 29 | "Staring in Ashanti" | Megan Rapinoe | July 18, 2019 (2019-07-18) | N/A |
| 30 | 30 | "Digital Hookah" | Dascha Polanco | July 22, 2019 (2019-07-22) | N/A |
| 31 | 31 | "Drop A Pin" | Common | July 25, 2019 (2019-07-25) | N/A |
| 32 | 32 | "Sightseeing Dog" | Billy Eichner | July 29, 2019 (2019-07-29) | N/A |
| 33 | 33 | "Alien Hook Off" | Anderson Cooper & Andy Cohen | August 1, 2019 (2019-08-01) | N/A |
| 34 | 34 | "It's A Boy" | DaBaby | October 14, 2019 (2019-10-14) | N/A |
| 35 | 35 | "Tech Flex" | Taraji P. Henson | October 17, 2019 (2019-10-17) | N/A |
| 36 | 36 | "Teeth On Layaway" | Ta-Nehisi Coates | October 21, 2019 (2019-10-21) | N/A |
| 37 | 37 | "West Indian Fence" | Gayle King & CC Sabathia | October 24, 2019 (2019-10-24) | N/A |
| 38 | 38 | "The Back Of Your Back" | Bill Burr | October 28, 2019 (2019-10-28) | N/A |
| 39 | 39 | "Un Jokkersteppen" | Bernie Sanders | October 31, 2019 (2019-10-31) | N/A |
| 40 | 40 | "Come Collect Uncle Daryl" | Anna Kendrick | November 4, 2019 (2019-11-04) | N/A |
| 41 | 41 | "Take Your Time Baby" | Kenan Thompson | November 7, 2019 (2019-11-07) | N/A |
| 42 | 42 | "From Deep" | Chris Hayes | November 11, 2019 (2019-11-11) | N/A |
| 43 | 43 | "Grab that Boomer" | Hasan Minhaj | November 14, 2019 (2019-11-14) | N/A |
| 44 | 44 | "That's Larping" | Shea Serrano | November 18, 2019 (2019-11-18) | N/A |
| 45 | 45 | "Dancing Bok Choy" | Chadwick Boseman, Elizabeth Warren | November 21, 2019 (2019-11-21) | N/A |

### Season 2 (2020)

| No. overall | No. in season | Title | Illustrious Guest(s) | Original release date | Viewers (millions) |
| 46 | 1 | "PJ Boys" | David Letterman | February 3, 2020 (2020-02-03) | N/A |
| 47 | 2 | "2020 Vision" | Alexandria Ocasio-Cortez | February 6, 2020 (2020-02-06) | N/A |
| 48 | 3 | "Hard To Get A Ticket" | Penn Badgley | February 10, 2020 (2020-02-10) | N/A |
| 49 | 4 | "Su-Su-Sucio" | Lakeith Stanfield | February 13, 2020 (2020-02-13) | N/A |
| 50 | 5 | "Full Body Roll" | Maxine Waters | February 20, 2020 (2020-02-20) | N/A |
| 51 | 6 | "That's A Lotta Rappin'" | John Mulaney | February 24, 2020 (2020-02-24) | N/A |
| 52 | 7 | "Woke Switcheroo" | Killer Mike | February 27, 2020 (2020-02-27) | N/A |
| 53 | 8 | "Whopping Good Time" | Missy Elliot | March 2, 2020 (2020-03-02) | N/A |
| 54 | 9 | "Bare Minimum Ally" | Nick Kroll | March 5, 2020 (2020-03-05) | N/A |
| 55 | 10 | "Dominican Leprechaun" | Wale | March 9, 2020 (2020-03-09) | N/A |
| 56 | 11 | "Big Beach Towel" | Seth Meyers | March 12, 2020 (2020-03-12) | N/A |
| 57 | 12 | "That Rona" | Anthony Fauci | March 30, 2020 (2020-03-30) | N/A |
| 58 | 13 | "Stay At Home Dad Jokes" | John Legend | April 2, 2020 (2020-04-02) | N/A |
| 59 | 14 | "R.O.I. from Nana" | Malcolm Gladwell | April 6, 2020 (2020-04-06) | N/A |
| 60 | 15 | "Van Gogh Album Cut" | Tracee Ellis Ross | April 9, 2020 (2020-04-09) | N/A |
| 61 | 16 | "You Mad Doofy" | Mark Cuban | April 13, 2020 (2020-04-13) | N/A |
| 62 | 17 | "Built-In Gratuity" | Joe Biden | April 16, 2020 (2020-04-16) | N/A |
| 63 | 18 | "Three Nuts and a Possible" | Alicia Keys | April 20, 2020 (2020-04-20) | N/A |
| 64 | 19 | "Dunk on Napoleon" | Issa Rae & Jay Ellis | April 23, 2020 (2020-04-23) | N/A |
| 65 | 20 | "A Caravan of Karens" | José Andrés | April 27, 2020 (2020-04-27) | N/A |
| 66 | 21 | "Bologna Goatee" | Rashida Jones, Alison Roman | April 30, 2020 (2020-04-30) | N/A |
| 67 | 22 | "The Goat's Always For Sale" | Spike Jonze and Beastie Boys | May 4, 2020 (2020-05-04) | N/A |
| 68 | 23 | "Terrifying and Sexy At The Same Time" | Billy Porter | May 7, 2020 (2020-05-07) | N/A |
| 69 | 24 | "The Metaphysical Hypothetical" | Dr. Nina | May 11, 2020 (2020-05-11) | N/A |
| 70 | 25 | "Infobars" | Katie Porter | May 14, 2020 (2020-05-14) | N/A |
| 71 | 26 | "Baline Human" | Gabrielle Union & Dwyane Wade | May 18, 2020 (2020-05-18) | N/A |
| 72 | 27 | "It's Been Asparamanced" | Jesse Williams | May 21, 2020 (2020-05-21) | N/A |
| 73 | 28 | "We Was Wolves" | N/A | May 25, 2020 (2020-05-25) | N/A |
| 74 | 29 | "One Big T-Zone" | Sara Jay, RMR | May 28, 2020 (2020-05-28) | N/A |
| 75 | 30 | "You Are The Jake" | Freddie Gibbs, Jamaal Bowman | July 5, 2020 (2020-07-05) | N/A |
| 76 | 31 | "It Be Your Own Mans" | Jon Stewart, Joey Chestnut | July 9, 2020 (2020-07-09) | N/A |
| 77 | 32 | "Cream of Corona" | Noname | July 12, 2020 (2020-07-12) | N/A |
| 78 | 33 | "Old School Glizzy" | Bubba Wallace, Judd Apatow | July 16, 2020 (2020-07-16) | N/A |
| 79 | 34 | "Different Coastal Work" | Lady A, Don Cheadle | July 19, 2020 (2020-07-19) | N/A |
| 80 | 35 | "Slow My Curve" | Kenny Stills, Eric Andre | July 23, 2020 (2020-07-23) | N/A |
| 81 | 36 | "Bottle Service Cheeks" | Andy Samberg | July 26, 2020 (2020-07-26) | N/A |
| 82 | 37 | "Six Figures In This" | Taylor Rooks | July 30, 2020 (2020-07-30) | N/A |
| 83 | 38 | "Sound It Out" | Stephen A. Smith | August 2, 2020 (2020-08-02) | N/A |
| 84 | 39 | "Ms. Papi" | Usain Bolt | August 6, 2020 (2020-08-06) | N/A |
| 85 | 40 | "Love Your Work" | Cori Bush, Seth Rogen | August 9, 2020 (2020-08-09) | N/A |
| 86 | 41 | "A Dickens of a Time" | Chloe x Halle, Jennifer McLeggan | August 13, 2020 (2020-08-13) | N/A |
| 87 | 42 | "Fully Accredited Institution" | Sue Bird | August 16, 2020 (2020-08-16) | N/A |
| 88 | 43 | "We Invented Sucio" | Jaime Harrison | August 20, 2020 (2020-08-20) | N/A |
| 89 | 44 | "Victoria Cakes" | Saweetie | August 23, 2020 (2020-08-23) | N/A |
| 90 | 45 | "Disloyal To Moisturizer" | Jaden Smith | August 27, 2020 (2020-08-27) | N/A |
| 91 | 46 | "Respect The Eagle" | Kamala Harris | September 13, 2020 (2020-09-13) | N/A |
| 92 | 47 | "Entanglement Eyes" | John David Washington | September 17, 2020 (2020-09-17) | N/A |
| 93 | 48 | "Brunch Boots" | Janelle Monáe | September 20, 2020 (2020-09-20) | N/A |
| 94 | 49 | "Coulda Been An Email" | Big Sean | September 24, 2020 (2020-09-24) | N/A |
| 95 | 50 | "New York Miracle" | Tony Hawk | September 27, 2020 (2020-09-27) | N/A |
| 96 | 51 | "Five Star Baby" | LL Cool J | October 1, 2020 (2020-10-01) | N/A |
| 97 | 52 | "Pandemic Type Beat" | Timbaland & Swizz Beatz | October 4, 2020 (2020-10-04) | N/A |
| 98 | 53 | "Between You And You" | Chika | October 8, 2020 (2020-10-08) | N/A |
| 99 | 54 | "Twelve Months of Papi" | Jason Derulo | October 11, 2020 (2020-10-11) | N/A |
| 100 | 55 | "These Phones Ain't Loyal" | Ethan Hawke | October 15, 2020 (2020-10-15) | N/A |
| 101 | 56 | "Mids Bop" | Yahya Abdul-Mateen II | October 18, 2020 (2020-10-18) | N/A |
| 102 | 57 | "Rookie Draft Day Pants" | Sarah Cooper | October 22, 2020 (2020-10-22) | N/A |
| 103 | 58 | "I'm Butt Nilzy" | HAIM, Borat | October 25, 2020 (2020-10-25) | N/A |
| 104 | 59 | "I Can Eyeball Bushels" | RZA | October 29, 2020 (2020-10-29) | N/A |
| 105 | 60 | "This Is Lighthearted Fun That We Havin' Right Now" | Chris Rock | November 1, 2020 (2020-11-01) | N/A |
| 106 | 61 | "DMFM: The Home of Boom Bap - Special" | Bobbito Garcia & DJ Stretch Armstrong, Roxanne Shante, City Girls, Bun B, Benny the Butcher, Juicy J, A$AP Ferg, Rick Ross, Sheila E, Cam'ron, Busta Rhymes | November 15, 2020 (2020-11-15) | N/A |
| 107 | 62 | "The Obama Interview" | Barack Obama | December 13, 2020 (2020-12-13) | N/A |

### Season 3 (2021)

| No. overall | No. in season | Title | Illustrious Guest(s) | Original release date | Viewers (millions) |
| 108 | 1 | "Right Off The Rip" | Stacey Abrams | January 31, 2021 (2021-01-31) | N/A |
| 109 | 2 | "Cook-‘em-All" | Freddie Gibbs | February 4, 2021 (2021-02-04) | N/A |
| 110 | 3 | "That’s On Y’all" | Jazmine Sullivan | February 7, 2021 (2021-02-07) | N/A |
| 111 | 4 | "I Smell Broke" | Whoopi Goldberg | February 11, 2021 (2021-02-11) | N/A |
| 112 | 5 | "Passive-Aggressive G.O.A.T." | Zendaya & John David Washington | February 14, 2021 (2021-02-14) | N/A |
| 113 | 6 | "We Be Here, He Be There" | Anthony Mackie | February 18, 2021 (2021-02-18) | N/A |
| 114 | 7 | "Move To Utica" | Ludacris | February 21, 2021 (2021-02-21) | N/A |
| 115 | 8 | "Bird Cousins" | Kelly Rowland | February 25, 2021 (2021-02-25) | N/A |
| 116 | 9 | "The Wild Cranium" | Travis "Taco" Bennett | February 28, 2021 (2021-02-28) | N/A |
| 117 | 10 | "East Coast Reggie" | Ramy Youssef | March 4, 2021 (2021-03-04) | N/A |
| 118 | 11 | "Mad Moist" | Delroy Lindo | March 7, 2021 (2021-03-07) | N/A |
| 119 | 12 | "Don't Come To My Funeral" | Eddie Huang | March 11, 2021 (2021-03-11) | N/A |
| 120 | 13 | "Pipes O'Clock" | Phoebe Bridgers | March 14, 2021 (2021-03-14) | N/A |
| 121 | 14 | "Puff Of Feathers" | Eddie Murphy, Jermaine Fowler | March 18, 2021 (2021-03-18) | N/A |
| 122 | 15 | "My Little Mule" | 24kGoldn, Benny the Butcher | March 21, 2021 (2021-03-21) | N/A |
| 123 | 16 | "L Machine" | Kenan Thompson | March 25, 2021 (2021-03-25) | N/A |
| 124 | 17 | "Future Hats" | Glenn Close | April 8, 2021 (2021-04-08) | N/A |
| 125 | 18 | "Half A Lip" | Andra Day | April 11, 2021 (2021-04-11) | N/A |
| 126 | 19 | "Weekend Dad" | Miguel | April 15, 2021 (2021-04-15) | N/A |
| 127 | 20 | "Twerking For No One" | J Balvin, Travon Free | April 18, 2021 (2021-04-18) | N/A |
| 128 | 21 | "The Cheek Detective" | Issa Rae | April 22, 2021 (2021-04-22) | N/A |
| 129 | 22 | "The Platypus Of Salads" | Demi Lovato | April 25, 2021 (2021-04-25) | N/A |
| 130 | 23 | "Yo Free Knowledge" | Julian Edelman | April 29, 2021 (2021-04-29) | N/A |
| 131 | 24 | "One Wood" | Taylour Paige | May 2, 2021 (2021-05-02) | N/A |
| 132 | 25 | "Wall Of Zeppoles" | Yo-yo Ma, Ziwe Fumudoh | May 6, 2021 (2021-05-06) | N/A |
| 133 | 26 | "Sturdy Limbs" | Lil Nas X | June 20, 2021 (2021-06-20) | N/A |
| 134 | 27 | "Watermarked X-Rays" | Yara Shahidi | June 24, 2021 (2021-06-24) | N/A |
| 135 | 28 | "Mid-Nup" | Don Cheadle | June 27, 2021 (2021-06-27) | N/A |
| 136 | 29 | "Full Body Toppy" | Lil Dicky & GaTa, Migos | July 1, 2021 (2021-07-01) | N/A |
| 137 | 30 | "Mad Habit" | Benny Blanco | July 8, 2021 (2021-07-08) | N/A |
| 138 | 31 | "Yearly Beret Budget" | Vince Staples | July 11, 2021 (2021-07-11) | N/A |
| 139 | 32 | "Ketchup & Oysters" | Barry Jenkins | July 15, 2021 (2021-07-15) | N/A |
| 140 | 33 | "Sea Of Uncles" | Cynthia Erivo, Andrew Callaghan | July 18, 2021 (2021-07-18) | N/A |
| 141 | 34 | "Bang Your Little Hammer" | H.E.R. | July 22, 2021 (2021-07-22) | N/A |
| 142 | 35 | "Staying In The Drafts" | Bobby Shmurda | July 25, 2021 (2021-07-25) | N/A |
| 143 | 36 | "Space Law" | Matt Damon | July 29, 2021 (2021-07-29) | N/A |
| 144 | 37 | "Yielding To Rebrinners" | Zazie Beetz | August 1, 2021 (2021-08-01) | N/A |
| 145 | 38 | "AKA Harry Nugs" | Eric Andre | August 5, 2021 (2021-08-05) | N/A |
| 146 | 39 | "Throw The Mid" | Idris Elba | August 8, 2021 (2021-08-08) | N/A |
| 147 | 40 | "Scamming Fee" | Marlon Wayans | August 12, 2021 (2021-08-12) | N/A |
| 148 | 41 | "Original Hairline" | Chance the Rapper | August 15, 2021 (2021-08-15) | N/A |
| 149 | 42 | "Wild Venomous" | John Turturro | August 19, 2021 (2021-08-19) | N/A |
| 150 | 43 | "It Might Be Reggaeton" | Nas | October 17, 2021 (2021-10-17) | N/A |
| 151 | 44 | "Not Guilty, Your Majesty" | Lewis Hamilton | October 21, 2021 (2021-10-21) | N/A |
| 152 | 45 | "Wild Romantical" | Baby Keem | October 24, 2021 (2021-10-24) | N/A |
| 153 | 46 | "African American Chlorophyll" | Dave Grohl | October 28, 2021 (2021-10-28) | N/A |
| 154 | 47 | "Prayer Warriors Assemble" | Yvonne Orji | October 31, 2021 (2021-10-31) | N/A |
| 155 | 48 | "Toddler Level Confidence" | ASAP Rocky | November 4, 2021 (2021-11-04) | N/A |
| 156 | 49 | "Clown-Like Actions" | Cordae | November 7, 2021 (2021-11-07) | N/A |
| 157 | 50 | "West Indian Dad Feet" | Dwayne Johnson | November 11, 2021 (2021-11-11) | N/A |
| 158 | 51 | "Ovary Majora" | Keke Palmer | November 14, 2021 (2021-11-14) | N/A |
| 159 | 52 | "Just Asking Questions" | Jeff Goldblum | November 18, 2021 (2021-11-18) | N/A |
| 160 | 53 | "Co-Potatoing" | Kevin Hart | November 21, 2021 (2021-11-21) | N/A |
| 161 | 54 | "A Very Roastable Shirt" | Tracy Morgan | December 2, 2021 (2021-12-02) | N/A |
| 162 | 55 | "Steamed Shirt" | French Montana | December 5, 2021 (2021-12-05) | N/A |
| 163 | 56 | "Sushi Hot Dogs" | Sandra Bullock | December 9, 2021 (2021-12-09) | N/A |
| 164 | 57 | "110% Polyester" | Michael B. Jordan | December 12, 2021 (2021-12-12) | N/A |
| 165 | 58 | "Bong, Done, Finito" | Keanu Reeves & Carrie-Anne Moss | December 16, 2021 (2021-12-16) | N/A |

### Season 4 (2022)

| No. overall | No. in season | Title | Illustrious Guest(s) | Original release date | Viewers (millions) |
| 166 | 1 | "Plain Slice" | Denzel Washington | March 10, 2022 (2022-03-10) | N/A |
| 167 | 2 | "It's Gonna Hit" | Tom Holland & Mark Wahlberg | March 24, 2022 (2022-03-24) | N/A |
| 168 | 3 | "Grab Your Bags" | Samuel L. Jackson | March 31, 2022 (2022-03-31) | N/A |
| 169 | 4 | "That's Brioche" | Pusha T | April 7, 2022 (2022-04-07) | N/A |
| 170 | 5 | "Big Hater Energy" | Michelle Yeoh | April 14, 2022 (2022-04-14) | N/A |
| 171 | 6 | "Lucite Situation" | Damson Idris | April 21, 2022 (2022-04-21) | N/A |
| 172 | 7 | "Cheater Belly" | Earl Sweatshirt | April 28, 2022 (2022-04-28) | N/A |
| 173 | 8 | "Bad Bills" | Jon Bernthal | May 5, 2022 (2022-05-05) | N/A |
| 174 | 9 | "Rum On Their Gums" | Chris Smalls | May 12, 2022 (2022-05-12) | N/A |
| 175 | 10 | "It's A Party Now" | Quinta Brunson | May 19, 2022 (2022-05-19) | N/A |
| 176 | 11 | "Bottles, Bottles, Bottles" | Jerrod Carmichael | May 26, 2022 (2022-05-26) | N/A |
| 177 | 12 | "Auto-Clapping" | Sam Jay | June 2, 2022 (2022-06-02) | N/A |
| 178 | 13 | "Say No To The Mustache" | Wanda Sykes | June 9, 2022 (2022-06-09) | N/A |
| 179 | 14 | "Science And Felonies" | Jeff Bridges, Seth Meyers | June 16, 2022 (2022-06-16) | N/A |
| 180 | 15 | "Coulda Been A Hero" | Derek Jeter, Mina Kimes | June 23, 2022 (2022-06-23) | N/A |

## Critical reception

Desus & Mero received positive reviews. Daniel D'addario wrote for Variety magazine: "Their perspective, in a sea of late-night shows all modeled on John Oliver's studiousness, feels genuinely new. And Desus and Mero showed enough comic resourcefulness, and enough enthusiasm and warmth, throughout their broadcast to make clear it's worth watching no matter who guests." Writing for Entertainment Weekly, Kristen Baldwin gave the show a B+ and stated in the review: "The initial outing revealed a few weaknesses in the new format, but it retained the humor, point of view, and boisterous energy that makes Desus and Mero an essential late-night addition." Marc Silver wrote for The Washington Post, "With their own wit and the help of veterans from the Stephen Colbert and John Oliver late-night shows, they bring a fresh and funny take and add all-too-rarely heard Black and Latino perspectives."

## Accolades

Hosts Desus and Mero received a 2019 Webby Special Achievement Award for their talk show.

## Awards and nominations

| Year | Award | Category | Nominee | Result |
| 2019 | TCA Awards | Outstanding Achievement in Variety, Talk, or Sketch | Desus & Mero | Nominated |
| 2020 | Critics' Choice Awards | Best Talk Show | Desus & Mero | Nominated |
| 2021 | Critics' Choice Awards | Best Talk Show | Desus & Mero | Nominated |
| 2021 | TCA Awards | Outstanding Achievement in Variety, Talk, or Sketch | Desus & Mero | Nominated |
| 2021 | NAACP Image Awards | Outstanding News/Information (Series or Special) (for "The Obama Interview") | Desus & Mero | Nominated |
| 2021 | Writers Guild of America Awards | Comedy/Variety Talk Series | Daniel Baker, Claire Friedman, Ziwerekoru Fumudoh, Josh Gondelman, Robert Kornhauser, Joel Martinez, Heben Nigatu, Mike Pielocik, and Julia Young; Showtime | Won |
| 2022 | Critics' Choice Awards | Best Talk Show | Desus & Mero | Pending |