# Arkansas Highway 21

Arkansas Highway 21 (AR 21) is a north–south state highway in north central Arkansas. The route runs 99.14 miles (159.55 km) from U.S. Route 64 (US 64) in Clarksville north across US 62 to the Missouri state line. The route is a two-lane highway with the exception of a brief concurrency with US 62, a four-lane highway, in Berryville.

## Route description

The route begins at US 64 in Clarksville near the Clarksville Municipal Airport and runs north to the Ozark National Forest. Highway 21 runs north to intersect Highway 292 near Ludwig and Ludwig Lake near Hillcrest in Johnson County. The route begins a concurrency with Highway 16 until Edwards Junction when Highway 21 turns north and serves as a southern terminus for Highway 43 at Boxley. Upon entering Madison County, the highway intersects Highway 74 in Kingston and passes the Bank of Kingston, a property on the National Register of Historic Places. Continuing north, Highway 21 intersects US 412 and enters Carroll County, before following US 412 for a short distance to the east, where it turns back north. The route continues north through Carroll County and enters Berryville, before a brief concurrency with US 62, followed by a concurrency with Highway 221, after which it heads north to the Missouri state line, where it continues as Missouri Route 13.

### Ozark Highlands Scenic Byway

A portion of Highway 21 was designated as the Ozark Highlands Scenic Byway in 2005 by the Arkansas State Highway and Transportation Department (AHTD). The byway begins at the southern terminus of Highway 21 at US 64 in Clarksville and runs north to the Buffalo National River near Boxley. Wildlife and scenic views are frequent along the nearly 35-mile-long (56 km) route. The highway is popular as a major route to the Ozark National Forest, the Ozark Highlands Trail, and the White River in addition to being the major travel route to cities in the area and points in southern Missouri.

## Major intersections

Mile markers reset at some concurrencies.
| County | Location | mi | km | Destinations | Notes |
| Johnson | Clarksville | 0.00 | 0.00 | US 64 (Main Street) | Southern terminus |
| Johnson | Clarksville | 0.41 | 0.66 | AR 164 east (Airport Road) | Western terminus of AR 164 |
| Johnson | Ludwig | 2.99 | 4.81 | AR 292 east | Western terminus of AR 292 |
| Johnson | Hillcrest | | | AR 818 – Arkansas Agricultural Experiment Station | |
| Module:Jctint/USA warning: Unused argument(s): ctdab |
| Newton | Fallsville | 28.13 | 45.27 | AR 16 west to AR 23 – Fayetteville | Southern end of AR 16 concurrency |
| Newton | Edwards Junction | 36.71 | 59.08 | AR 16 east to AR 7 | Northern end of AR 16 concurrency |
| Newton | Boxley | 48.04 | 77.31 | AR 43 north – Ponca, Jasper | Southern terminus of AR 43 |
| Madison | Kingston | 57.45 | 92.46 | AR 74 west to AR 23 | Roundabout; eastern terminus of AR 74 |
| Carroll | ​ | 64.66 | 104.06 | US 412 west – Huntsville | Southern end of US 412 concurrency |
| Carroll | ​ | 0.00 | 0.00 | US 412 east – Alpena | Northern end of US 412 concurrency |
| Carroll | Berryville | 17.56 | 28.26 | US 62 east – Harrison | Southern end of US 62 concurrency |
| Carroll | Berryville | 0.00 | 0.00 | US 62 west (AR 221 south) – Eureka Springs | Northern end of US 62 concurrency; southern end of AR 221 concurrency |
| Carroll | Berryville | 2.16 | 3.48 | AR 221 north | Northern end of AR 221 concurrency |
| Carroll | Oak Grove | 12.55 | 20.20 | AR 103 south – Green Forest | Northern terminus of AR 103 |
| Carroll | Blue Eye | 16.67 | 26.83 | AR 311 south | Northern terminus of AR 311 |
| Carroll | Blue Eye | 16.92 | 27.23 | Route 13 north – Springfield | Continuation into Missouri |
| 1.000 mi = 1.609 km; 1.000 km = 0.621 mi Concurrency terminus ||||||