# National Register of Historic Places listings in Tuscola County, Michigan

The following is a list of Registered Historic Places in Tuscola County, Michigan.      This National Park Service list is complete through NPS recent listings posted February 28, 2025.
| | Name on the Register | Image | Date listed | Location | City or town | Description |
| 1 | R.C. Burtis House | R.C. Burtis House More images | June 26, 1975 (#75000962) | 2163 S. Ringle Rd. 43°26′52″N 83°31′20″W﻿ / ﻿43.447778°N 83.522222°W﻿ / 43.447778; -83.522222﻿ (R.C. Burtis House) | Vassar | |
| 2 | First Presbyterian Church | First Presbyterian Church | November 15, 2006 (#06001029) | 6505 Church St. 43°36′08″N 83°10′28″W﻿ / ﻿43.602222°N 83.174444°W﻿ / 43.602222; -83.174444﻿ (First Presbyterian Church) | Cass City | |
| 3 | Lovira Hart, Jr., and Esther Maria Parker Farm | Lovira Hart, Jr., and Esther Maria Parker Farm | June 16, 2004 (#04000599) | 9491 Frankenmuth Rd. 43°20′07″N 83°40′34″W﻿ / ﻿43.335278°N 83.676111°W﻿ / 43.335278; -83.676111﻿ (Lovira Hart, Jr., and Esther Maria Parker Farm) | Tuscola | |
| 4 | Hotel Columbia | Hotel Columbia | January 22, 1992 (#91001998) | 194 E. Huron Ave. 43°22′16″N 83°34′55″W﻿ / ﻿43.371111°N 83.581944°W﻿ / 43.371111; -83.581944﻿ (Hotel Columbia) | Vassar | |
| 5 | Hotel Montague | Hotel Montague | July 9, 1991 (#91000875) | 200 S. State St. 43°29′19″N 83°23′51″W﻿ / ﻿43.488611°N 83.3975°W﻿ / 43.488611; -83.3975﻿ (Hotel Montague) | Caro | |
| 6 | McKinley School | McKinley School | March 24, 1972 (#72000655) | 510 Butler St. 43°22′05″N 83°34′35″W﻿ / ﻿43.368056°N 83.576389°W﻿ / 43.368056; -83.576389﻿ (McKinley School) | Vassar | |
| 7 | Millington Bank Building | Millington Bank Building | November 29, 1995 (#95001387) | 8534 State Rd. 43°16′49″N 83°31′49″W﻿ / ﻿43.280278°N 83.530278°W﻿ / 43.280278; -83.530278﻿ (Millington Bank Building) | Millington | |
| 8 | William J. and Lovila (Wooley) Moore House | William J. and Lovila (Wooley) Moore House | March 27, 2024 (#100010162) | 123 North Almer St. 43°29′26″N 83°23′51″W﻿ / ﻿43.490556°N 83.397500°W﻿ / 43.490556; -83.397500﻿ (William J. and Lovila (Wooley) Moore House) | Caro | |
| 9 | Townsend North House | Townsend North House | April 13, 1977 (#77000723) | 325 N. Main St. 43°22′31″N 83°34′33″W﻿ / ﻿43.375278°N 83.575833°W﻿ / 43.375278; -83.575833﻿ (Townsend North House) | Vassar | |
| 10 | Randall House | Randall House | November 7, 1976 (#76001035) | 5927 Treasurer Rd. 43°20′22″N 83°19′20″W﻿ / ﻿43.339444°N 83.322222°W﻿ / 43.339444; -83.322222﻿ (Randall House) | Mayville | Octagon house, built 1870 |
| 11 | Smith House | Smith House | March 16, 1972 (#72000656) | 113-115 Prospect St. 43°22′19″N 83°35′09″W﻿ / ﻿43.371944°N 83.585833°W﻿ / 43.371944; -83.585833﻿ (Smith House) | Vassar | |
| 12 | Trinity Episcopal Church | Trinity Episcopal Church | May 12, 1975 (#75000961) | 106 Joy St. 43°29′16″N 83°23′48″W﻿ / ﻿43.487778°N 83.396667°W﻿ / 43.487778; -83.396667﻿ (Trinity Episcopal Church) | Caro | |
| 13 | Tuscola County Courthouse | Tuscola County Courthouse | December 6, 1996 (#96001419) | 440 N. State St. 43°29′27″N 83°23′35″W﻿ / ﻿43.490833°N 83.393056°W﻿ / 43.490833; -83.393056﻿ (Tuscola County Courthouse) | Caro | |
| 14 | Watrous General Store | Watrous General Store | October 1, 1974 (#74000998) | 4607 W. Caro Rd. 43°27′06″N 83°31′28″W﻿ / ﻿43.451667°N 83.524444°W﻿ / 43.451667; -83.524444﻿ (Watrous General Store) | Watrousville | |
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