# National Register of Historic Places listings in Charleston County, South Carolina

This is a list of the National Register of Historic Places listings in Charleston County, South Carolina.
This is intended to be a complete list of the properties and districts on the National Register of Historic Places in Charleston County, South Carolina, United States. The locations of National Register properties and districts for which the latitude and longitude coordinates are included below, may be seen in an online map.
There are 207 properties and districts listed on the National Register in the county, including 43 National Historic Landmarks. The city of Charleston is the location of 105 of these properties and districts, including 34 of the National Historic Landmarks; they are listed separately, while 105 properties and districts in the remaining parts of the county, including 9 National Historic Landmarks, are listed here. Another 5 properties in Charleston County outside Charleston were once listed but have been removed. Three properties and districts — the Ashley River Historic District, Ashley River Road, and the Secessionville Historic District — are split between the city and the other parts of the county, and are thus included on both lists.
This National Park Service list is complete through NPS recent listings posted February 28, 2025.
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* GPX (secondary coordinates)

## Current listings

| | Name on the Register | Image | Date listed | Location | City or town | Description |
| 1 | Ashley Hall Plantation | Ashley Hall Plantation | June 5, 1975 (#75001691) | Address restricted | West Ashley | |
| 2 | Ashley River Historic District | Ashley River Historic District More images | September 12, 1994 (#93001514) | Roughly along the Ashley River from just east of South Carolina Highway 165, near Watson Hill (North Charleston), to the Seaboard Coast Line Railroad bridge 32°53′58″N 80°07′00″W﻿ / ﻿32.8994°N 80.1167°W﻿ / 32.8994; -80.1167﻿ (Ashley River Historic District) | North Charleston | Extends into Charleston and Dorchester County |
| 3 | Ashley River Road | Ashley River Road More images | November 21, 1983 (#83003831) | South Carolina Highway 61 between Church Creek and South Carolina Highway 165 32°53′43″N 80°08′08″W﻿ / ﻿32.8953°N 80.1356°W﻿ / 32.8953; -80.1356﻿ (Ashley River Road) | Summerville | Extends into Charleston and Dorchester County |
| 4 | Atlanticville Historic District | Upload image | September 6, 2007 (#07000927) | Middle St., Jasper Boulevard, and Myrtle Ave. between Stations 22½ and 26 32°45′55″N 79°49′57″W﻿ / ﻿32.7653°N 79.8325°W﻿ / 32.7653; -79.8325﻿ (Atlanticville Historic District) | Sullivan's Island | |
| 5 | Auld Mound | Upload image | October 15, 1970 (#70000583) | Address Restricted | Mount Pleasant | |
| 6 | Alexander Bache U.S. Coast Survey Line | Alexander Bache U.S. Coast Survey Line More images | October 5, 2007 (#07001082) | 8377 State Cabin Rd. 32°30′20″N 80°18′37″W﻿ / ﻿32.5056°N 80.3103°W﻿ / 32.5056; -80.3103﻿ (Alexander Bache U.S. Coast Survey Line) | Edisto Island | |
| 7 | Bailey's Store | Bailey's Store More images | November 28, 1986 (#86003204) | 1444 South Carolina Highway 174 32°33′36″N 80°16′47″W﻿ / ﻿32.56009°N 80.27961°W﻿ / 32.56009; -80.27961﻿ (Bailey's Store) | Edisto Island | Now occupied by With These Hands Gallery. |
| 8 | Barnwell House | Upload image | November 25, 1980 (#80003657) | South of Charleston 32°41′54″N 80°24′22″W﻿ / ﻿32.6983°N 80.4061°W﻿ / 32.6983; -80.4061﻿ (Barnwell House) | Adams Run | |
| 9 | Bass Pond Site | Upload image | April 24, 1979 (#79002379) | Address Restricted | Kiawah Island | |
| 10 | Battery Gadsden | Battery Gadsden More images | June 25, 1974 (#74001842) | 2017 Ion Ave. 32°45′36″N 79°50′23″W﻿ / ﻿32.76°N 79.8397°W﻿ / 32.76; -79.8397﻿ (Battery Gadsden) | Sullivan's Island | Now houses the Edgar Allan Poe Branch of the Charleston County Library |
| 11 | Battery Thomson | Battery Thomson More images | June 25, 1974 (#74001843) | 2013 Ion Ave. 32°45′33″N 79°50′28″W﻿ / ﻿32.7592°N 79.8411°W﻿ / 32.7592; -79.8411﻿ (Battery Thomson) | Sullivan's Island | |
| 12 | Bethel African Methodist Episcopal Church | Bethel African Methodist Episcopal Church | June 22, 2004 (#04000651) | 369 Drayton St. 33°05′21″N 79°27′26″W﻿ / ﻿33.0893°N 79.4571°W﻿ / 33.0893; -79.4571﻿ (Bethel African Methodist Episcopal Church) | McClellanville | |
| 13 | Bleak Hall Plantation Outbuildings | Bleak Hall Plantation Outbuildings | March 7, 1973 (#73001698) | 4 miles southeast of Edisto Island off South Carolina Highway 174 32°33′10″N 80°14′05″W﻿ / ﻿32.5528°N 80.2347°W﻿ / 32.5528; -80.2347﻿ (Bleak Hall Plantation Outbuildings) | Edisto Island | |
| 14 | Brick House Ruin | Brick House Ruin More images | April 15, 1970 (#70000580) | South of Edisto Island 32°36′05″N 80°19′32″W﻿ / ﻿32.6014°N 80.3256°W﻿ / 32.6014; -80.3256﻿ (Brick House Ruin) | Edisto Island | |
| 15 | Brooklands Plantation | Brooklands Plantation More images | May 5, 1987 (#86003198) | Off Laurel Hill Rd. on Scanawah Island 32°34′19″N 80°21′19″W﻿ / ﻿32.5719°N 80.3553°W﻿ / 32.5719; -80.3553﻿ (Brooklands Plantation) | Edisto Island | |
| 16 | Buzzard's Island Site | Upload image | October 15, 1970 (#70000584) | Address Restricted | Mount Pleasant | |
| 17 | Cape Romain Lighthouses | Cape Romain Lighthouses More images | November 12, 1981 (#81000563) | Southeast of McClellanville on Lighthouse Island 33°01′06″N 79°22′27″W﻿ / ﻿33.0183°N 79.3742°W﻿ / 33.0183; -79.3742﻿ (Cape Romain Lighthouses) | McClellanville | |
| 18 | Cassina Point | Cassina Point More images | November 28, 1986 (#86003210) | 1642 Clark Road, Edisto, South Carolina 32°35′29″N 80°15′03″W﻿ / ﻿32.5914°N 80.2508°W﻿ / 32.5914; -80.2508﻿ (Cassina Point) | Edisto Island | |
| 19 | Charleston Naval Hospital | Upload image | January 25, 2021 (#100006050) | 3600 Rivers Ave. 32°51′27″N 79°58′46″W﻿ / ﻿32.8576°N 79.9794°W﻿ / 32.8576; -79.9794﻿ (Charleston Naval Hospital) | North Charleston | |
| 20 | Charleston Naval Hospital Historic District | Charleston Naval Hospital Historic District | October 22, 2010 (#10000851) | Former Charleston Navy Base including parts of Turnbull Avenue, Hobby Street, Avenues F-I, Truxton Avenue, and Marine Avenue 32°51′51″N 79°58′02″W﻿ / ﻿32.8642°N 79.9672°W﻿ / 32.8642; -79.9672﻿ (Charleston Naval Hospital Historic District) | North Charleston | |
| 21 | Charleston Navy Yard Historic District | Charleston Navy Yard Historic District More images | August 9, 2006 (#06000699) | Roughly bounded by 1st St., Hobson Ave., Ave. D, 4th and 5th Sts., and the drydocks between 1st and 13th Sts. 32°51′43″N 79°57′46″W﻿ / ﻿32.8619°N 79.9628°W﻿ / 32.8619; -79.9628﻿ (Charleston Navy Yard Historic District) | North Charleston | |
| 22 | Charleston Navy Yard Officers' Quarters Historic District | Charleston Navy Yard Officers' Quarters Historic District More images | March 2, 2007 (#07000100) | Turnbull Ave., Everglades Dr., Navy Way, and portions of Hobson Ave. and Blackstop Dr. 32°52′08″N 79°58′09″W﻿ / ﻿32.8689°N 79.9692°W﻿ / 32.8689; -79.9692﻿ (Charleston Navy Yard Officers' Quarters Historic District) | North Charleston | |
| 23 | Christ Church | Christ Church More images | November 27, 1972 (#72001201) | 2304 Highway 17N 32°50′38″N 79°48′50″W﻿ / ﻿32.8439°N 79.8139°W﻿ / 32.8439; -79.8139﻿ (Christ Church) | Mount Pleasant | |
| 24 | Cook's Old Field Cemetery | Upload image | May 9, 2003 (#01000679) | 0.5 miles north of Rifle Range Rd. 32°50′20″N 79°48′13″W﻿ / ﻿32.8389°N 79.8036°W﻿ / 32.8389; -79.8036﻿ (Cook's Old Field Cemetery) | Mount Pleasant | |
| 25 | Crawford's Plantation House | Crawford's Plantation House More images | June 8, 1993 (#93000475) | 8202 Oyster Factory Rd. 32°32′15″N 80°18′16″W﻿ / ﻿32.5375°N 80.3044°W﻿ / 32.5375; -80.3044﻿ (Crawford's Plantation House) | Edisto Island | |
| 26 | Edisto Island Baptist Church | Edisto Island Baptist Church More images | April 1, 1982 (#82003839) | 1644 South Carolina Highway 174 32°34′22″N 80°17′03″W﻿ / ﻿32.5728°N 80.2842°W﻿ / 32.5728; -80.2842﻿ (Edisto Island Baptist Church) | Edisto Island | |
| 27 | Edisto Island Presbyterian Church | Edisto Island Presbyterian Church More images | June 24, 1971 (#71000754) | 1.9 miles north of Edisto Island on South Carolina Highway 174 32°34′44″N 80°17′49″W﻿ / ﻿32.5789°N 80.2969°W﻿ / 32.5789; -80.2969﻿ (Edisto Island Presbyterian Church) | Edisto Island | |
| 28 | Engineering-Management Building | Engineering-Management Building | September 4, 2020 (#100005002) | 2260 Noisette Blvd. 32°51′55″N 79°58′16″W﻿ / ﻿32.8654°N 79.9711°W﻿ / 32.8654; -79.9711﻿ (Engineering-Management Building) | North Charleston | |
| 29 | Fairfield Plantation | Fairfield Plantation More images | July 25, 1974 (#74001838) | North of McClellanville 33°10′58″N 79°24′18″W﻿ / ﻿33.1828°N 79.405°W﻿ / 33.1828; -79.405﻿ (Fairfield Plantation) | McClellanville | |
| 30 | Fig Island Site | Upload image | October 15, 1970 (#70000585) | Address Restricted | Edisto Island | |
| 31 | Folly North Site-38CH1213 | Upload image | October 2, 2003 (#03001001) | Address Restricted | Folly Beach | |
| 32 | Fort Johnson/Powder Magazine | Fort Johnson/Powder Magazine More images | September 14, 1972 (#72001197) | East end of Ft. Johnson Road, in South Carolina Department of Natural Resources compound 32°45′08″N 79°53′55″W﻿ / ﻿32.7522°N 79.8986°W﻿ / 32.7522; -79.8986﻿ (Fort Johnson/Powder Magazine) | James Island | |
| 33 | Fort Moultrie Quartermaster and Support Facilities Historic District | Fort Moultrie Quartermaster and Support Facilities Historic District More images | September 6, 2007 (#07000925) | Middle St. and Thompson Ave., between Stations 14 and 16.5 32°45′35″N 79°51′11″W﻿ / ﻿32.7597°N 79.8531°W﻿ / 32.7597; -79.8531﻿ (Fort Moultrie Quartermaster and Support Facilities Historic District) | Sullivan's Island | |
| 34 | Fort Palmetto | Upload image | August 11, 1982 (#82003842) | Christ Church Parish 32°49′23″N 79°45′56″W﻿ / ﻿32.8231°N 79.7656°W﻿ / 32.8231; -79.7656﻿ (Fort Palmetto) | Hamlin Sound | |
| 35 | Fort Pemberton Site | Upload image | November 21, 1978 (#78002498) | Shoreline of the Stono River on the northwestern corner of James Island 32°45′35″N 80°00′03″W﻿ / ﻿32.7597°N 80.0008°W﻿ / 32.7597; -80.0008﻿ (Fort Pemberton Site) | James Island | |
| 36 | Frogmore | Upload image | May 5, 1987 (#86003203) | South of Pine Landing Rd. near the intersection of South Carolina Highway 174 and Laurel Hill Rd. 32°35′16″N 80°21′21″W﻿ / ﻿32.5878°N 80.3558°W﻿ / 32.5878; -80.3558﻿ (Frogmore) | Edisto Island | |
| 37 | General Asbestos and Rubber Company (GARCO) Main Mill | General Asbestos and Rubber Company (GARCO) Main Mill | February 28, 2017 (#100000687) | 0 O'Hear Ave. 32°53′01″N 79°58′30″W﻿ / ﻿32.8835°N 79.9749°W﻿ / 32.8835; -79.9749﻿ (General Asbestos and Rubber Company (GARCO) Main Mill) | North Charleston | |
| 38 | Paul Grimball House Ruins | Upload image | November 28, 1986 (#86003190) | Address Restricted | Edisto Island | |
| 39 | Grove Plantation | Grove Plantation More images | August 25, 1978 (#78002495) | Southwest of Adams Run off South Carolina Highway 174 32°39′54″N 80°23′37″W﻿ / ﻿32.665°N 80.3936°W﻿ / 32.665; -80.3936﻿ (Grove Plantation) | Adams Run | |
| 40 | H. L. Hunley (submarine) | H. L. Hunley (submarine) More images | December 29, 1978 (#78003412) | Located on the old Naval base in North Charleston 32°44′00″N 79°46′00″W﻿ / ﻿32.7333°N 79.7667°W﻿ / 32.7333; -79.7667﻿ (H. L. Hunley (submarine)) | North Charleston | |
| 41 | Hampton Plantation | Hampton Plantation More images | April 15, 1970 (#70000582) | 1950 Rutledge Rd. 33°12′01″N 79°26′09″W﻿ / ﻿33.2003°N 79.4358°W﻿ / 33.2003; -79.4358﻿ (Hampton Plantation) | McClellanville | |
| 42 | Hanckel Mound | Upload image | October 15, 1970 (#70000586) | Address Restricted | Rockville | |
| 43 | Harrietta Plantation | Harrietta Plantation More images | September 18, 1975 (#75001695) | 5 miles east of McClellanville off U.S. Route 17 33°10′10″N 79°23′37″W﻿ / ﻿33.1694°N 79.3936°W﻿ / 33.1694; -79.3936﻿ (Harrietta Plantation) | McClellanville | |
| 44 | Horse Island | Upload image | November 10, 1970 (#70000587) | Address Restricted | Rockville | |
| 45 | Host of America Motel | Host of America Motel | September 25, 2020 (#100005609) | 3245 Rivers Ave. 32°51′12″N 79°58′21″W﻿ / ﻿32.8534°N 79.9726°W﻿ / 32.8534; -79.9726﻿ (Host of America Motel) | North Charleston | |
| 46 | Hutchinson House | Hutchinson House | May 5, 1987 (#86003218) | 7666 Point of Pines Rd. 32°34′12″N 80°15′26″W﻿ / ﻿32.5700°N 80.2571°W﻿ / 32.5700; -80.2571﻿ (Hutchinson House) | Edisto Island | |
| 47 | John's Island Presbyterian Church | John's Island Presbyterian Church | November 3, 1975 (#75001692) | 10 miles west of Charleston on South Carolina Highway 20 32°41′12″N 80°04′56″W﻿ / ﻿32.6867°N 80.0822°W﻿ / 32.6867; -80.0822﻿ (John's Island Presbyterian Church) | Johns Island | |
| 48 | King Cemetery | Upload image | June 13, 2000 (#00000586) | 1.1 miles northeast of the junction of U.S. Route 17 and S-19-38 32°46′10″N 80°22′51″W﻿ / ﻿32.7694°N 80.3808°W﻿ / 32.7694; -80.3808﻿ (King Cemetery) | Adams Run | |
| 49 | Lawton-Seabrook Cemetery | Upload image | June 12, 2017 (#100001075) | 7938 Steamboat Landing Rd. 32°35′24″N 80°17′42″W﻿ / ﻿32.5899°N 80.2949°W﻿ / 32.5899; -80.2949﻿ (Lawton-Seabrook Cemetery) | Edisto Island | |
| 50 | Lighthouse Point Shell Ring (38CH12) | Upload image | October 14, 1990 (#90001505) | Address Restricted | James Island | |
| 51 | Long Point Plantation (38CH321) | Upload image | March 20, 1986 (#86000468) | Address Restricted | Mount Pleasant | |
| 52 | Lucas Family Cemetery | Lucas Family Cemetery More images | May 18, 1998 (#98000425) | Ellen Dr. 32°47′45″N 79°52′18″W﻿ / ﻿32.7958°N 79.8717°W﻿ / 32.7958; -79.8717﻿ (Lucas Family Cemetery) | Mount Pleasant | |
| 53 | Magnolia Plantation and Gardens | Magnolia Plantation and Gardens More images | December 11, 1972 (#72001198) | 10 miles northwest of Charleston on South Carolina Highway 61 32°52′29″N 80°05′21″W﻿ / ﻿32.8747°N 80.0892°W﻿ / 32.8747; -80.0892﻿ (Magnolia Plantation and Gardens) | West Ashley | |
| 54 | Marine Barracks, Charleston Navy Yard | Marine Barracks, Charleston Navy Yard More images | October 16, 2020 (#100005676) | Truxtun Ave. between Marine and Goldberg Aves. 32°51′48″N 79°58′26″W﻿ / ﻿32.8633°N 79.9739°W﻿ / 32.8633; -79.9739﻿ (Marine Barracks, Charleston Navy Yard) | North Charleston | |
| 55 | Marshlands Plantation House | Marshlands Plantation House | March 30, 1973 (#73001700) | Northern side of Fort Sumter Dr. 32°45′01″N 79°54′03″W﻿ / ﻿32.7503°N 79.9008°W﻿ / 32.7503; -79.9008﻿ (Marshlands Plantation House) | James Island | The house was moved from its original location at the old Naval Base in North Charleston for preservation. |
| 56 | McClellanville Historic District | Upload image | March 23, 1982 (#82003845) | Pinckney, Lofton, Charlotte, Church, Water, Oak, Venning, Legare, Morrison, and Scotia Sts. 33°05′06″N 79°27′43″W﻿ / ﻿33.085°N 79.4619°W﻿ / 33.085; -79.4619﻿ (McClellanville Historic District) | McClellanville | |
| 57 | W. Gresham Meggett High and Elementary School | Upload image | February 20, 2018 (#100002098) | 1929 Grimball Rd. 32°42′25″N 79°58′34″W﻿ / ﻿32.7069°N 79.9762°W﻿ / 32.7069; -79.9762﻿ (W. Gresham Meggett High and Elementary School) | Charleston vicinity | |
| 58 | Middleton's Plantation | Upload image | May 6, 1971 (#71000755) | 3.5 miles north of Edisto Island off South Carolina Highway 174 32°33′25″N 80°19′48″W﻿ / ﻿32.5569°N 80.33°W﻿ / 32.5569; -80.33﻿ (Middleton's Plantation) | Edisto Island | Not to be confused with Middleton Place in nearby Dorchester County |
| 59 | Morris Island Lighthouse | Upload image | June 28, 1982 (#82003837) | 6 mi. SE of Charleston 32°42′06″N 79°53′59″W﻿ / ﻿32.7017°N 79.8997°W﻿ / 32.7017; -79.8997﻿ (Morris Island Lighthouse) | Folly Beach | https://catalog.archives.gov/id/118997393 |
| 60 | Mosquito Beach Historic District | Mosquito Beach Historic District More images | September 23, 2019 (#100004409) | Mosquito Beach Rd. 32°40′22″N 79°58′57″W﻿ / ﻿32.6728°N 79.9824°W﻿ / 32.6728; -79.9824﻿ (Mosquito Beach Historic District) | James Island vicinity | |
| 61 | Moultrieville Historic District | Moultrieville Historic District More images | September 6, 2007 (#07000928) | Middle St. and Osceola Ave., between stations 11 and 12 32°45′39″N 79°51′33″W﻿ / ﻿32.7608°N 79.8592°W﻿ / 32.7608; -79.8592﻿ (Moultrieville Historic District) | Sullivan's Island | Includes several late-19th and early-20th century beach houses and Stella Maris Church designed by John Henry Devereux |
| 62 | Mount Pleasant Historic District | Mount Pleasant Historic District | March 30, 1973 (#73001701) | Bounded by Charleston Harbor, Shem Creek, Royall Ave., and McCants Dr. 32°47′10″N 79°52′33″W﻿ / ﻿32.7861°N 79.8758°W﻿ / 32.7861; -79.8758﻿ (Mount Pleasant Historic District) | Mount Pleasant | |
| 63 | Moving Star Hall | Upload image | June 17, 1982 (#82003843) | River Rd. 32°40′55″N 80°01′33″W﻿ / ﻿32.6819°N 80.0258°W﻿ / 32.6819; -80.0258﻿ (Moving Star Hall) | Johns Island | |
| 64 | Oak Island | Oak Island More images | November 28, 1986 (#86003202) | 1 mile off Oak Island Rd. on Westbank Creek 32°35′39″N 80°15′05″W﻿ / ﻿32.5942°N 80.2514°W﻿ / 32.5942; -80.2514﻿ (Oak Island) | Edisto Island | |
| 65 | Oakland Plantation House | Oakland Plantation House More images | July 13, 1977 (#77001218) | 7 miles north of Charleston Harbor on U.S. Route 17 32°51′59″N 79°45′18″W﻿ / ﻿32.8664°N 79.755°W﻿ / 32.8664; -79.755﻿ (Oakland Plantation House) | Mount Pleasant | |
| 66 | Old Courthouse | Old Courthouse | May 6, 1971 (#71000760) | 331 King St. 32°47′06″N 79°51′50″W﻿ / ﻿32.7850°N 79.8639°W﻿ / 32.7850; -79.8639﻿ (Old Courthouse) | Mount Pleasant | |
| 67 | Old Georgetown Road | Upload image | June 27, 2014 (#14000382) | Old Georgetown Road between south bank of the South Santee River and SC 45 33°09′15″N 79°28′46″W﻿ / ﻿33.1541°N 79.4795°W﻿ / 33.1541; -79.4795﻿ (Old Georgetown Road) | McClellanville | |
| 68 | Old House Plantation | Old House Plantation | May 14, 1971 (#71000756) | Northeast of Edisto Island via South Carolina Highway 174; also 0.5 miles east of the junction of South Carolina Highway 174 and Oak Island Rd., then right on a dirt road 32°34′49″N 80°15′37″W﻿ / ﻿32.5803°N 80.2603°W﻿ / 32.5803; -80.2603﻿ (Old House Plantation) | Edisto Island | Second address represents a boundary increase of May 5, 1987 |
| 69 | Dr. John B. Patrick House | Dr. John B. Patrick House | February 9, 1995 (#94001628) | 1820 Middle St. 32°45′35″N 79°50′36″W﻿ / ﻿32.7597°N 79.8433°W﻿ / 32.7597; -79.8433﻿ (Dr. John B. Patrick House) | Sullivan's Island | |
| 70 | Peter's Point Plantation | Peter's Point Plantation | June 19, 1973 (#73001699) | 9084 Peter's Point Road, Edisto, South Carolina 32°32′19″N 80°20′22″W﻿ / ﻿32.5386°N 80.3394°W﻿ / 32.5386; -80.3394﻿ (Peter's Point Plantation) | Edisto Island | |
| 71 | Phillips Community Historic District | Upload image | September 7, 2023 (#100008589) | SC 41, approx. between Virginia Rouse and Joe Rouse Rds., roughly bounded by Horlbeck Cr., Dunes West, and Park West 32°52′59″N 79°48′39″W﻿ / ﻿32.8830°N 79.8108°W﻿ / 32.8830; -79.8108﻿ (Phillips Community Historic District) | Mount Pleasant vicinity | |
| 72 | Presbyterian Manse | Upload image | May 14, 1971 (#71000757) | Northwest of Edisto Island off South Carolina Highway 174 32°34′04″N 80°18′34″W﻿ / ﻿32.5678°N 80.3094°W﻿ / 32.5678; -80.3094﻿ (Presbyterian Manse) | Edisto Island | |
| 73 | Paul Pritchard Shipyard | Upload image | September 17, 1974 (#74001839) | Address Restricted | Mount Pleasant | |
| 74 | The Progressive Club | The Progressive Club | October 24, 2007 (#07001109) | 3377 River Rd. 32°40′37″N 80°02′26″W﻿ / ﻿32.6769°N 80.0406°W﻿ / 32.6769; -80.0406﻿ (The Progressive Club) | Johns Island | |
| 75 | Prospect Hill | Prospect Hill More images | November 28, 1986 (#86003196) | Off Laurel Hill Rd. 32°34′54″N 80°23′04″W﻿ / ﻿32.5817°N 80.3844°W﻿ / 32.5817; -80.3844﻿ (Prospect Hill) | Edisto Island | |
| 76 | Remley Point Cemetery | Remley Point Cemetery More images | May 30, 2002 (#02000570) | 0.2 miles northeast of the junction of 3rd and 4th Aves. 32°48′51″N 79°53′53″W﻿ / ﻿32.8142°N 79.8981°W﻿ / 32.8142; -79.8981﻿ (Remley Point Cemetery) | Mount Pleasant | |
| 77 | Rockville Historic District | Rockville Historic District | June 13, 1972 (#72001202) | Town of Rockville on the northern bank of Bohicket Creek 32°36′18″N 80°11′35″W﻿ / ﻿32.605°N 80.1931°W﻿ / 32.605; -80.1931﻿ (Rockville Historic District) | Rockville | |
| 78 | St. James Episcopal Church, Santee | St. James Episcopal Church, Santee More images | April 15, 1970 (#70000581) | 17 miles south of Georgetown on the Santee River 33°10′19″N 79°27′56″W﻿ / ﻿33.1719°N 79.4656°W﻿ / 33.1719; -79.4656﻿ (St. James Episcopal Church, Santee) | Georgetown | |
| 79 | John Seabrook Plantation Bridge | Upload image | October 9, 1974 (#74001841) | Northwest of Rockville off South Carolina Highway 700 32°37′38″N 80°12′37″W﻿ / ﻿32.6272°N 80.2103°W﻿ / 32.6272; -80.2103﻿ (John Seabrook Plantation Bridge) | Rockville | |
| 80 | William Seabrook House | William Seabrook House More images | May 6, 1971 (#71000758) | North of Edisto Island off South Carolina Highway 174 32°36′06″N 80°16′53″W﻿ / ﻿32.6017°N 80.2814°W﻿ / 32.6017; -80.2814﻿ (William Seabrook House) | Edisto Island | |
| 81 | Seashore Farmers' Lodge No. 767 | Seashore Farmers' Lodge No. 767 More images | October 3, 2007 (#07001043) | Northeastern corner of the junction of Sol Legare and Old Sol Legare Rds. 32°40′54″N 79°58′02″W﻿ / ﻿32.6817°N 79.9672°W﻿ / 32.6817; -79.9672﻿ (Seashore Farmers' Lodge No. 767) | James Island | |
| 82 | Seaside Plantation House | Seaside Plantation House More images | January 21, 1982 (#82003840) | Off South Carolina Highway 174 32°31′14″N 80°17′23″W﻿ / ﻿32.5206°N 80.2897°W﻿ / 32.5206; -80.2897﻿ (Seaside Plantation House) | Edisto Island | |
| 83 | Seaside School | Upload image | June 17, 1994 (#94000602) | 1097 South Carolina Highway 174 32°32′51″N 80°16′54″W﻿ / ﻿32.5475°N 80.2817°W﻿ / 32.5475; -80.2817﻿ (Seaside School) | Edisto Island | |
| 84 | Secessionville Historic District | Secessionville Historic District More images | October 1, 1979 (#79002378) | North of Folly Beach 32°42′18″N 79°56′35″W﻿ / ﻿32.705°N 79.9431°W﻿ / 32.705; -79.9431﻿ (Secessionville Historic District) | Folly Beach | Extends into Charleston |
| 85 | Sewee Mound | Sewee Mound More images | October 15, 1970 (#70000571) | Salt Pond Road (FS Road 243) 32°59′48″N 79°36′37″W﻿ / ﻿32.9967°N 79.6103°W﻿ / 32.9967; -79.6103﻿ (Sewee Mound) | Awendaw | |
| 86 | Slave Street, Smokehouse, and Allee, Boone Hall Plantation | Slave Street, Smokehouse, and Allee, Boone Hall Plantation More images | July 14, 1983 (#93001512) | North of Mt. Pleasant off U.S. Route 17; also Long Point Rd. west of its junction with U.S. Routes 17/701 32°51′29″N 79°49′23″W﻿ / ﻿32.8581°N 79.8231°W﻿ / 32.8581; -79.8231﻿ (Slave Street, Smokehouse, and Allee, Boone Hall Plantation) | Mount Pleasant | Second location represents a boundary increase of January 21, 1994, the Boone Hall Plantation House and Historic Landscape |
| 87 | Snee Farm-Charles Pinckney National Historic Site | Snee Farm-Charles Pinckney National Historic Site More images | April 13, 1973 (#73001702) | 6 miles west of Mt. Pleasant at 1254 Long Point Rd. 32°50′46″N 79°49′29″W﻿ / ﻿32.8461°N 79.8247°W﻿ / 32.8461; -79.8247﻿ (Snee Farm-Charles Pinckney National Historic Site) | Mount Pleasant | Boundary increase approved October 10, 2021. |
| 88 | Stono River Slave Rebellion Site | Stono River Slave Rebellion Site | May 30, 1974 (#74001840) | Off U.S. Route 17 on the western bank of the Wallace River 32°47′14″N 80°08′44″W﻿ / ﻿32.7872°N 80.1456°W﻿ / 32.7872; -80.1456﻿ (Stono River Slave Rebellion Site) | Rantowles | |
| 89 | Sullivan's Island Historic District | Sullivan's Island Historic District More images | September 6, 2007 (#07000929) | Middle St., I'on Ave., and Central Ave. between Stations 17 and 18½ 32°45′33″N 79°50′45″W﻿ / ﻿32.7592°N 79.8458°W﻿ / 32.7592; -79.8458﻿ (Sullivan's Island Historic District) | Sullivan's Island | |
| 90 | Summit Plantation House | Summit Plantation House More images | July 28, 1983 (#83002188) | Off County Road 390 32°41′37″N 80°17′10″W﻿ / ﻿32.6936°N 80.2861°W﻿ / 32.6936; -80.2861﻿ (Summit Plantation House) | Adams Run | |
| 91 | Sunnyside | Sunnyside More images | November 28, 1986 (#86003216) | Off the northern side of Peter's Point Rd.; also north of the junction of Peters Point and Creekwood Rd. 32°33′57″N 80°17′50″W﻿ / ﻿32.5658°N 80.2972°W﻿ / 32.5658; -80.2972﻿ (Sunnyside) | Edisto Island | A plantation on Edisto Island. Second location represents a boundary increase, the Sunnyside Plantation Foreman's House |
| 92 | Towles Farmstead | Upload image | January 21, 1994 (#93001513) | 4595 and 4611 Towles Rd. 32°43′14″N 80°11′06″W﻿ / ﻿32.7206°N 80.185°W﻿ / 32.7206; -80.185﻿ (Towles Farmstead) | Meggett | |
| 93 | Hephzibah Jenkins Townsend's Tabby Oven Ruins | Upload image | May 5, 1987 (#86003200) | Address Restricted | Edisto Island | |
| 94 | Trinity Church | Trinity Church | May 14, 1971 (#71000759) | 1589 South Carolina Highway 174 32°34′10″N 80°17′01″W﻿ / ﻿32.5694°N 80.2836°W﻿ / 32.5694; -80.2836﻿ (Trinity Church) | Edisto Island | |
| 95 | U.S. Coast Guard Historic District | U.S. Coast Guard Historic District More images | June 19, 1973 (#73001703) | Ion Ave. between Station 18 and Station 18½ 32°45′27″N 79°50′33″W﻿ / ﻿32.7575°N 79.8425°W﻿ / 32.7575; -79.8425﻿ (U.S. Coast Guard Historic District) | Sullivan's Island | |
| 96 | Unnamed Battery No. 1 | Upload image | August 11, 1982 (#82003838) | Clark's Point 32°43′15″N 79°56′07″W﻿ / ﻿32.7208°N 79.9353°W﻿ / 32.7208; -79.9353﻿ (Unnamed Battery No. 1) | James Island | |
| 97 | USS CLAMAGORE (SS-343) | USS CLAMAGORE (SS-343) More images | June 29, 1989 (#89001229) | Patriot's Point 32°47′23″N 79°54′28″W﻿ / ﻿32.7897°N 79.9078°W﻿ / 32.7897; -79.9078﻿ (USS CLAMAGORE (SS-343)) | Mount Pleasant | Scrapped in 2022; landmark designation withdrawn in 2024. |
| 98 | USS LAFFEY | USS LAFFEY More images | April 12, 1983 (#83002189) | West of Mt. Pleasant on the eastern side of Charleston Harbor 32°47′23″N 79°54′28″W﻿ / ﻿32.7897°N 79.9078°W﻿ / 32.7897; -79.9078﻿ (USS LAFFEY) | Mount Pleasant | |
| 99 | USS YORKTOWN (CV-10) | USS YORKTOWN (CV-10) More images | November 10, 1982 (#82001519) | West of Mt. Pleasant on the eastern side of Charleston Harbor 32°47′26″N 79°54′31″W﻿ / ﻿32.7906°N 79.9086°W﻿ / 32.7906; -79.9086﻿ (USS YORKTOWN (CV-10)) | Mount Pleasant | |
| 100 | Arnoldus Vander Horst House | Upload image | October 25, 1973 (#73001697) | 25 miles southwest of Charleston on Kiawah Island 32°37′00″N 80°04′24″W﻿ / ﻿32.6167°N 80.0733°W﻿ / 32.6167; -80.0733﻿ (Arnoldus Vander Horst House) | Kiawah Island | |
| 101 | The Wedge | The Wedge More images | November 25, 1980 (#80003660) | Northeast of McClellanville 33°10′17″N 79°23′57″W﻿ / ﻿33.1714°N 79.3992°W﻿ / 33.1714; -79.3992﻿ (The Wedge) | McClellanville | |
| 102 | Wescott Road | Wescott Road More images | November 28, 1986 (#86003195) | West of South Carolina Highway 174 32°33′44″N 80°16′53″W﻿ / ﻿32.5622°N 80.2814°W﻿ / 32.5622; -80.2814﻿ (Wescott Road) | Edisto Island | |
| 103 | Wilkinson-Boineau House | Wilkinson-Boineau House More images | January 21, 1999 (#98001644) | 5185 South Carolina Highway 174 32°43′10″N 80°20′56″W﻿ / ﻿32.7195°N 80.3490°W﻿ / 32.7195; -80.3490﻿ (Wilkinson-Boineau House) | Adams Run | |
| 104 | Willtown Bluff | Willtown Bluff | January 8, 1974 (#74001830) | Southwest of Adams Run at the end of County Road 55 on the banks of the S. Edisto River 32°40′54″N 80°24′54″W﻿ / ﻿32.6817°N 80.415°W﻿ / 32.6817; -80.415﻿ (Willtown Bluff) | Adams Run | |
| 105 | Windsor Plantation | Upload image | July 23, 1974 (#74001837) | East of South Carolina Highway 174 near Little Edisto 32°35′58″N 80°20′41″W﻿ / ﻿32.5994°N 80.3447°W﻿ / 32.5994; -80.3447﻿ (Windsor Plantation) | Edisto Island | |

## Former listings

| | Name on the Register | Image | Date listed | Date removed | Location | City or town | Description |
| 1 | Laurel Hill | Upload image | September 23, 1985 (#85002359) | March 15, 2000 | | McClellanville | Destroyed by Hurricane Hugo on September 21, 1989. |
| 2 | Point of Pines Plantation Slave Cabin | Upload image | November 28, 1986 (#86003213) | October 23, 2013 | Point of Pines Rd. 32°34′39″N 80°14′25″W﻿ / ﻿32.5775°N 80.2403°W﻿ / 32.5775; -80.2403﻿ (Point of Pines Plantation Slave Cabin) | Edisto Island | Moved to the National Museum of African American History and Culture in Washington, D.C. in May 2013. |
| 3 | NS Savannah | NS Savannah More images | November 14, 1982 (#82001518) | December 8, 2005 | Partiot's Points | Mount Pleasant | Moved to Newport News, Virginia |
| 4 | Williams Graded School | Upload image | August 21, 1980 (#80003659) | January 27, 1983 | Pinckney St. | Lincolnville | Destroyed by arsonist on June 20, 1982. |