# National Register of Historic Places listings in Mississippi County, Missouri

This is a list of the National Register of Historic Places listings in Mississippi County, Missouri.
This is intended to be a complete list of the properties and districts on the National Register of Historic Places in Mississippi County, Missouri, United States. Latitude and longitude coordinates are provided for many National Register properties and districts; these locations may be seen together in a map.
There are 12 properties and districts listed on the National Register in the county.
This National Park Service list is complete through NPS recent listings posted February 28, 2025.
Download coordinates as:
* KML
* GPX (all coordinates)
* GPX (primary coordinates)
* GPX (secondary coordinates)

## Current listings

| | Name on the Register | Image | Date listed | Location | City or town | Description |
| 1 | Beckwith's Fort Archeological Site | Beckwith's Fort Archeological Site | July 29, 1969 (#69000113) | County Road 502 36°41′36″N 89°14′08″W﻿ / ﻿36.693333°N 89.235556°W﻿ / 36.693333; -89.235556﻿ (Beckwith's Fort Archeological Site) | Wolf Island | Also known as Towosahgy State Historic Site |
| 2 | Crosno Fortified Village Archeological Site | Upload image | May 21, 1969 (#69000112) | Southeastern quarter of Section 23, Township 25 North, Range 17 East$^{:231}$ 36°47′41″N 89°10′51″W﻿ / ﻿36.794722°N 89.180833°W﻿ / 36.794722; -89.180833﻿ (Crosno Fortified Village Archeological Site) | Crosno | |
| 3 | Hearnes Site | Hearnes Site | November 26, 1973 (#73001047) | U.S. Route 60 east of Charleston, immediately west of the Charleston Country Club 36°55′23″N 89°18′12″W﻿ / ﻿36.923056°N 89.303333°W﻿ / 36.923056; -89.303333﻿ (Hearnes Site) | Charleston | |
| 4 | Hess Archeological Site | Upload image | July 12, 1974 (#74001081) | Midway between Pinhook and Towosahgy State Historic Site, east of Missouri Route F1$^{:235}$ 36°43′08″N 89°15′04″W﻿ / ﻿36.718889°N 89.251111°W﻿ / 36.718889; -89.251111﻿ (Hess Archeological Site) | East Prairie | |
| 5 | Hoecake Village Archeological Site | Upload image | January 13, 1972 (#72000723) | 2.5 miles (4.0 km) west of Pinhook 36°44′20″N 89°18′46″W﻿ / ﻿36.738889°N 89.312778°W﻿ / 36.738889; -89.312778﻿ (Hoecake Village Archeological Site) | East Prairie | Smithsonian trinomial 23MI8 |
| 6 | McCutchen Theatre | McCutchen Theatre | August 6, 2019 (#100004271) | 106 E. Commercial St. 36°55′24″N 89°20′59″W﻿ / ﻿36.9234°N 89.3498°W﻿ / 36.9234; -89.3498﻿ (McCutchen Theatre) | Charleston | |
| 7 | Missouri Pacific Depot | Missouri Pacific Depot | November 30, 1972 (#72000722) | East of intersecting branches of the Missouri Pacific Railroad 36°55′22″N 89°21′28″W﻿ / ﻿36.922778°N 89.357778°W﻿ / 36.922778; -89.357778﻿ (Missouri Pacific Depot) | Charleston | |
| 8 | Moore House | Moore House | September 18, 1980 (#80002380) | 403 N. Main St. 36°55′35″N 89°21′02″W﻿ / ﻿36.926389°N 89.350556°W﻿ / 36.926389; -89.350556﻿ (Moore House) | Charleston | |
| 9 | Mueller Archeological Site | Upload image | August 13, 1974 (#74001082) | Address Restricted | East Prairie | |
| 10 | O'Bryan Ridge Archeological District | Upload image | November 9, 1972 (#72000724) | Missouri Route 77 south of Wyatt 36°52′02″N 89°12′54″W﻿ / ﻿36.867222°N 89.215000°W﻿ / 36.867222; -89.215000﻿ (O'Bryan Ridge Archeological District) | Wyatt | |
| 11 | Russell Hotel | Russell Hotel | June 27, 2022 (#100007832) | 200 East Commercial St. 36°55′24″N 89°20′58″W﻿ / ﻿36.9234°N 89.3494°W﻿ / 36.9234; -89.3494﻿ (Russell Hotel) | Charleston | |
| 12 | Jacob Swank House | Jacob Swank House | April 13, 1973 (#73001048) | 0.2 miles west of Charleston on U.S. Routes 60 and 62 36°55′20″N 89°22′16″W﻿ / ﻿36.922222°N 89.371000°W﻿ / 36.922222; -89.371000﻿ (Jacob Swank House) | Charleston | |