# 2021 French Open – Men's singles

Novak Djokovic defeated Stefanos Tsitsipas in the final, 6–7$^{(6–8)}$, 2–6, 6–3, 6–2, 6–4 to win the men's singles tennis title at the 2021 French Open. It was his second French Open title and 19th major title overall. Djokovic became the first man to achieve the double career Grand Slam in the Open Era, and the first player in the Open Era to win a major after coming back from two-sets-to-love down in two matches during the same major. Tsitsipas was the first Greek player to reach a major final. It also marked the second consecutive year a man trailed by two sets in a major final yet rallied to win, following Dominic Thiem's victory at the 2020 US Open. It was the first time since 2004 that the final went to five sets; on that occasion, Gastón Gaudio also came from two sets down to win the title.
Rafael Nadal was the four-time defending champion, but lost to Djokovic in the semifinals. Nadal's defeat marked only his third loss out of 108 French Open matches, including his first loss in 14 semifinal appearances at the tournament. Djokovic became the only man to defeat Nadal two times at the French Open. It was the pair's record-extending 58th meeting.
Djokovic and Daniil Medvedev were in contention for the world No. 1 ranking; Djokovic retained the ranking after Medvedev lost in the quarterfinals.
Nadal and Roger Federer were attempting to win a record-breaking 21st major title and become the outright leader in the men's singles major tally. Federer, like Djokovic, was attempting to become the first man in the Open Era to achieve the double career Grand Slam; this would be the 2009 champion's last French Open appearance. This was the only time that the Big Three, the three most successful men's singles major champions of all time, were in the same half of the draw at a major.
For the first time in the Open Era, no French players reached the third round. Thiem's first-round defeat guaranteed a new French Open finalist from the bottom half of the draw; Tsitsipas ultimately emerged as that finalist. Carlos Alcaraz was the youngest player since Djokovic in 2005 to win a match at the French Open, and the youngest to reach the third round since Andrei Medvedev in 1992.

## Seeds

    01. Novak Djokovic (champion)
    02. Daniil Medvedev (quarterfinals)
    03. Rafael Nadal (semifinals)
    04. Dominic Thiem (first round)
    05. Stefanos Tsitsipas (final)
    06. Alexander Zverev (semifinals)
    07. Andrey Rublev (first round)
    08. Roger Federer (fourth round, withdrew)
    09. Matteo Berrettini (quarterfinals)
    10. Diego Schwartzman (quarterfinals)
    11. Roberto Bautista Agut (second round)
    12. Pablo Carreño Busta (fourth round)
    13. David Goffin (first round)
    14. Gaël Monfils (second round)
    15. Casper Ruud (third round)
    16. Grigor Dimitrov (first round, retired)
    17. Milos Raonic (withdrew)
    18. Jannik Sinner (fourth round)
    19. Hubert Hurkacz (first round)
    20. Félix Auger-Aliassime (first round)
    21. Alex de Minaur (second round)
    22. Cristian Garín (fourth round)
    23. Karen Khachanov (second round)
    24. Aslan Karatsev (second round)
    25. Dan Evans (first round)
    26. Lorenzo Sonego (first round)
    27. Fabio Fognini (third round)
    28. Nikoloz Basilashvili (second round)
    29. Ugo Humbert (first round)
    30. Taylor Fritz (second round)
    31. John Isner (third round)
    32. Reilly Opelka (third round)
Click on the seed number of a player to go to their draw section.

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final | Final | Final | Final | Final |
| 1 | Novak Djokovic | 6 | 6 | 6$^5$ | 7 | | | | | | | | | | | | | | |
| 9 | Matteo Berrettini | 3 | 2 | 7$^7$ | 5 | | | | | | | | | | | | | | |
| 9 | Matteo Berrettini | 3 | 2 | 7$^7$ | 5 | 1 | Novak Djokovic | 3 | 6 | 7$^7$ | 6 | | | | | | | | |
| | | | | | | 3 | Rafael Nadal | 6 | 3 | 6$^4$ | 2 | | | | | | | | |
| 3 | Rafael Nadal | 6 | 4 | 6 | 6 | 3 | Rafael Nadal | 6 | 3 | 6$^4$ | 2 | | | | | | | | |
| 10 | Diego Schwartzman | 3 | 6 | 4 | 0 | | | | | | | | | | | | | | |
| 10 | Diego Schwartzman | 3 | 6 | 4 | 0 | | | | | | | | 1 | Novak Djokovic | 6$^6$ | 2 | 6 | 6 | 6 |
| | | | | | | | | | | | | | 5 | Stefanos Tsitsipas | 7$^8$ | 6 | 3 | 2 | 4 |
| 6 | Alexander Zverev | 6 | 6 | 6 | | | | | | | | | | | | | | | | 5 | Stefanos Tsitsipas | 7$^8$ | 6 | 3 | 2 | 4 |
| | Alejandro Davidovich Fokina | 4 | 1 | 1 | | | | | | | | | | | | | | | |
| | Alejandro Davidovich Fokina | 4 | 1 | 1 | | 6 | Alexander Zverev | 3 | 3 | 6 | 6 | 3 | | | | | | | |
| | | | | | | 5 | Stefanos Tsitsipas | 6 | 6 | 4 | 4 | 6 | | | | | | | |
| 5 | Stefanos Tsitsipas | 6 | 7$^7$ | 7 | | 5 | Stefanos Tsitsipas | 6 | 6 | 4 | 4 | 6 | | | | | | | |
| 2 | Daniil Medvedev | 3 | 6$^3$ | 5 | | | | | | | | | | | | | | | |

### Top half
#### Section 1

| First round | First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Second round | Third round | Third round | Third round | Third round | Third round | Third round | Third round | Fourth round | Fourth round | Fourth round | Fourth round | Fourth round | Fourth round | Fourth round |
| 1 | N Djokovic | 6 | 6 | 6 | | | | | | | | | | | | | | | | | | | | | |
| | T Sandgren | 2 | 4 | 2 | | 1 | N Djokovic | 6 | 6 | 6 | | | | | | | | | | | | | | | |
| | L Pouille | 3 | 1 | 3 | | | P Cuevas | 3 | 2 | 4 | | | | | | | | | | | | | | | |
| | P Cuevas | 6 | 6 | 6 | | | | | | | | 1 | N Djokovic | 6 | 6 | 6 | | | | | | | | | |
| | S Caruso | 4 | 6 | 6$^4$ | 2 | | | | | | | | R Berankis | 1 | 4 | 1 | | | | | | | | | |
| | J Duckworth | 6 | 3 | 7$^7$ | 6 | | J Duckworth | 5 | 6 | 6$^4$ | 0 | | | | | | | | | | | | | | |
| | R Berankis | 6 | 6 | 2 | 6 | | R Berankis | 7 | 2 | 7$^7$ | 6 | | | | | | | | | | | | | | |
| 29 | U Humbert | 4 | 4 | 6 | 4 | | | | | | | | | | | | | | 1 | N Djokovic | 6$^7$ | 6$^2$ | 6 | 6 | 4 |
| 21 | A de Minaur | 6 | 6 | 7$^7$ | | | | | | | | | | | | | | | | L Musetti | 7$^9$ | 7$^7$ | 1 | 0 | 0$^r$ |
| | S Travaglia | 2 | 4 | 6$^4$ | | 21 | A de Minaur | 4 | 1 | 6 | 1 | | | | | | | | | | | | | | |
| | Y Uchiyama | 6 | 1 | 2 | 4 | | M Cecchinato | 6 | 6 | 3 | 6 | | | | | | | | | | | | | | |
| | M Cecchinato | 3 | 6 | 6 | 6 | | | | | | | | M Cecchinato | 6 | 4 | 3 | 6 | 3 | | | | | | | |
| | J-W Tsonga | 4 | 2 | 6 | 6$^5$ | | | | | | | | L Musetti | 3 | 6 | 6 | 3 | 6 | | | | | | | |
| | Y Nishioka | 6 | 6 | 3 | 7$^7$ | | Y Nishioka | 5 | 3 | 2 | | | | | | | | | | | | | | | |
| | L Musetti | 6 | 7 | 7$^7$ | | | L Musetti | 7 | 6 | 6 | | | | | | | | | | | | | | | |
| 13 | D Goffin | 0 | 5 | 6$^3$ | | | | | | | | | | | | | | | | | | | | | |

#### Section 2

| First round | First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Second round | Third round | Third round | Third round | Third round | Third round | Third round | Fourth round | Fourth round | Fourth round |
| 9 | M Berrettini | 6 | 6 | 4 | 6 | | | | | | | | | | | | | | | |
| Q | T Daniel | 0 | 4 | 6 | 4 | 9 | M Berrettini | 6 | 6 | 6 | | | | | | | | | | |
| | F Coria | 6 | 7$^7$ | 6 | | | F Coria | 3 | 3 | 2 | | | | | | | | | | |
| | F López | 3 | 6$^4$ | 2 | | | | | | | | 9 | M Berrettini | 7$^8$ | 6 | 6 | | | | |
| | K Anderson | 5 | 4 | 6 | 6$^4$ | | | | | | | | S-w Kwon | 6$^6$ | 3 | 4 | | | | |
| | S-w Kwon | 7 | 6 | 2 | 7$^7$ | | S-w Kwon | 6 | 7 | 7 | | | | | | | | | | |
| | A Seppi | 6 | 7$^{10}$ | 4 | 6 | | A Seppi | 4 | 5 | 5 | | | | | | | | | | |
| 20 | F Auger-Aliassime | 3 | 6$^8$ | 6 | 4 | | | | | | | | | | | | | 9 | M Berrettini | w/o |
| 30 | T Fritz | 6 | 6 | 6 | | | | | | | | | | | | | | 8 | R Federer | |
| | J Sousa | 4 | 2 | 4 | | 30 | T Fritz | 3 | 2 | 6 | 4 | | | | | | | | | |
| WC | M Bourgue | 3 | 3 | 4 | | | D Koepfer | 6 | 6 | 3 | 6 | | | | | | | | | |
| | D Koepfer | 6 | 6 | 6 | | | | | | | | | D Koepfer | 6$^5$ | 7$^7$ | 6$^4$ | 5 | | | |
| | M Čilić | 7$^8$ | 6 | 6 | | | | | | | | 8 | R Federer | 7$^7$ | 6$^3$ | 7$^7$ | 7 | | | |
| WC | A Rinderknech | 6$^6$ | 1 | 2 | | | M Čilić | 2 | 6 | 6$^4$ | 2 | | | | | | | | | |
| Q | D Istomin | 2 | 4 | 3 | | 8 | R Federer | 6 | 2 | 7$^7$ | 6 | | | | | | | | | |
| 8 | R Federer | 6 | 6 | 6 | | | | | | | | | | | | | | | | |

#### Section 3

| First round | First round | First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Second round | Third round | Third round | Third round | Third round | Third round | Fourth round | Fourth round | Fourth round | Fourth round | Fourth round |
| 3 | R Nadal | 6 | 6 | 7$^7$ | | | | | | | | | | | | | | | | | | |
| | A Popyrin | 3 | 2 | 6$^3$ | | | 3 | R Nadal | 6 | 7 | 6 | | | | | | | | | | | |
| WC | H Gaston | 1 | 4 | 2 | | | | R Gasquet | 0 | 5 | 2 | | | | | | | | | | | |
| | R Gasquet | 6 | 6 | 6 | | | | | | | | | 3 | R Nadal | 6 | 6 | 6 | | | | | |
| | C Norrie | 7 | 7$^7$ | 6 | | | | | | | | | | C Norrie | 3 | 3 | 3 | | | | | |
| Q | B Fratangelo | 5 | 6$^5$ | 2 | | | | C Norrie | 4 | 6 | 6 | 6 | | | | | | | | | | |
| | L Harris | 7 | 6 | 6 | | | | L Harris | 6 | 3 | 3 | 2 | | | | | | | | | | |
| 26 | L Sonego | 5 | 4 | 4 | | | | | | | | | | | | | | 3 | R Nadal | 7 | 6 | 6 |
| 18 | J Sinner | 6 | 4 | 6$^4$ | 7 | 6 | | | | | | | | | | | | 18 | J Sinner | 5 | 3 | 0 |
| | P-H Herbert | 1 | 6 | 7$^7$ | 5 | 4 | 18 | J Sinner | 6 | 7 | 3 | 6 | | | | | | | | | | |
| | G Mager | 6 | 3 | 6 | 7 | | | G Mager | 1 | 5 | 6 | 3 | | | | | | | | | | |
| LL | P Gojowczyk | 2 | 6 | 4 | 5 | | | | | | | | 18 | J Sinner | 6 | 7 | 6 | | | | | |
| | M Ymer | 6 | 0 | 4 | 6 | 6 | | | | | | | | M Ymer | 1 | 5 | 3 | | | | | |
| | R Carballés Baena | 4 | 6 | 6 | 2 | 2 | | M Ymer | 6 | 2 | 6 | 6 | | | | | | | | | | |
| | A Ramos Viñolas | 6 | 6$^6$ | 4 | 4 | | 14 | G Monfils | 0 | 6 | 4 | 3 | | | | | | | | | | |
| 14 | G Monfils | 1 | 7$^8$ | 6 | 6 | | | | | | | | | | | | | | | | | |

#### Section 4

| First round | First round | First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Second round | Third round | Third round | Third round | Third round | Third round | Fourth round | Fourth round | Fourth round | Fourth round | Fourth round |
| 10 | D Schwartzman | 6 | 6 | 6 | | | | | | | | | | | | | | | | | | |
| PR | Y-h Lu | 2 | 2 | 3 | | | 10 | D Schwartzman | 6 | 6 | 6 | | | | | | | | | | | |
| | A Mannarino | 5 | 6 | 5 | 2 | | | A Bedene | 4 | 2 | 4 | | | | | | | | | | | |
| | A Bedene | 7 | 3 | 7 | 6 | | | | | | | | 10 | D Schwartzman | 6 | 6 | 6 | | | | | |
| PR | P Kohlschreiber | 7$^7$ | 6 | 2 | 6 | | | | | | | | PR | P Kohlschreiber | 4 | 2 | 1 | | | | | |
| | F Verdasco | 6$^3$ | 2 | 6 | 4 | | PR | P Kohlschreiber | 6 | 7$^7$ | 4 | 6 | | | | | | | | | | |
| Q | J Brooksby | 3 | 4 | 4 | | | 24 | A Karatsev | 3 | 6$^4$ | 6 | 1 | | | | | | | | | | |
| 24 | A Karatsev | 6 | 6 | 6 | | | | | | | | | | | | | | 10 | D Schwartzman | 7$^{11}$ | 6 | 7 |
| 28 | N Basilashvili | 6 | 6 | 0 | 6 | | | | | | | | | | | | | | J-L Struff | 6$^9$ | 4 | 5 |
| | D Lajović | 4 | 3 | 6 | 2 | | 28 | N Basilashvili | 4 | 2 | 4 | | | | | | | | | | | |
| Q | C Alcaraz | 6 | 2 | 6 | 7$^7$ | | Q | C Alcaraz | 6 | 6 | 6 | | | | | | | | | | | |
| Q | B Zapata Miralles | 3 | 6 | 1 | 6$^4$ | | | | | | | | Q | C Alcaraz | 4 | 6$^3$ | 2 | | | | | |
| | F Bagnis | 7 | 6 | 6 | | | | | | | | | | J-L Struff | 6 | 7$^7$ | 6 | | | | | |
| WC | B Bonzi | 5 | 3 | 4 | | | | F Bagnis | 5 | 6$^1$ | 4 | | | | | | | | | | | |
| | J-L Struff | 6 | 7$^8$ | 4 | 3 | 6 | | J-L Struff | 7 | 7$^7$ | 6 | | | | | | | | | | | |
| 7 | A Rublev | 3 | 6$^6$ | 6 | 6 | 4 | | | | | | | | | | | | | | | | |

### Bottom half
#### Section 5

| First round | First round | First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Second round | Second round | Third round | Third round | Third round | Third round | Third round | Fourth round | Fourth round | Fourth round | Fourth round | Fourth round |
| 6 | A Zverev | 3 | 3 | 6 | 6 | 6 | | | | | | | | | | | | | | | | | |
| Q | O Otte | 6 | 6 | 2 | 2 | 0 | 6 | A Zverev | 7$^7$ | 6 | 7$^7$ | | | | | | | | | | | | |
| Q | R Safiullin | 7$^7$ | 1 | 6 | 6 | | Q | R Safiullin | 6$^4$ | 3 | 6$^1$ | | | | | | | | | | | | |
| Q | C Taberner | 6$^4$ | 6 | 0 | 2 | | | | | | | | | 6 | A Zverev | 6 | 7 | 6 | | | | | |
| | C Moutet | 3 | 7$^{12}$ | 6$^2$ | 5 | | | | | | | | | | L Đere | 2 | 5 | 2 | | | | | |
| | L Đere | 6 | 6$^{10}$ | 7$^7$ | 7 | | | L Đere | 4 | 4 | 6 | 6 | 6 | | | | | | | | | | |
| | M Kecmanović | 1 | 6 | 6 | 6 | | | M Kecmanović | 6 | 6 | 3 | 2 | 3 | | | | | | | | | | |
| 25 | D Evans | 6 | 3 | 3 | 4 | | | | | | | | | | | | | | 6 | A Zverev | 6 | 6 | 6 |
| 23 | K Khachanov | 6 | 6 | 6 | | | | | | | | | | | | | | | | K Nishikori | 4 | 1 | 1 |
| | J Veselý | 1 | 2 | 3 | | | 23 | K Khachanov | 6 | 2 | 6 | 4 | 4 | | | | | | | | | | |
| | K Nishikori | 6 | 6$^4$ | 6 | 4 | 6 | | K Nishikori | 4 | 6 | 2 | 6 | 6 | | | | | | | | | | |
| Q | A Giannessi | 4 | 7$^7$ | 3 | 6 | 4 | | | | | | | | | K Nishikori | 7 | 0 | | | | | | |
| | Y Hanfmann | 1 | 3 | 6 | 2 | | | | | | | | | Q | H Laaksonen | 5 | 0$^r$ | | | | | | |
| Q | H Laaksonen | 6 | 6 | 4 | 6 | | Q | H Laaksonen | 6 | 2 | 6 | 6 | | | | | | | | | | | |
| Q | M Vilella Martínez | 4 | 4 | 2 | | | 11 | R Bautista Agut | 3 | 6 | 3 | 2 | | | | | | | | | | | |
| 11 | R Bautista Agut | 6 | 6 | 6 | | | | | | | | | | | | | | | | | | | |

#### Section 6

| First round | First round | First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Second round | Second round | Third round | Third round | Third round | Third round | Third round | Third round | Third round | Fourth round | Fourth round | Fourth round | Fourth round | Fourth round |
| 15 | C Ruud | 5 | 6 | 6 | 7$^7$ | | | | | | | | | | | | | | | | | | | | |
| | B Paire | 7 | 2 | 1 | 6$^4$ | | 15 | C Ruud | 6 | 6 | 6 | | | | | | | | | | | | | | |
| PR | K Majchrzak | 6 | 2 | 6 | 6 | | PR | K Majchrzak | 3 | 2 | 4 | | | | | | | | | | | | | | |
| WC | A Cazaux | 4 | 6 | 4 | 4 | | | | | | | | | 15 | C Ruud | 6$^3$ | 6 | 6$^6$ | 6 | 5 | | | | | |
| | A Davidovich Fokina | 6 | 6 | 6 | | | | | | | | | | | A Davidovich Fokina | 7$^7$ | 2 | 7$^8$ | 0 | 7 | | | | | |
| | M Kukushkin | 4 | 4 | 3 | | | | A Davidovich Fokina | 6 | 6 | 5 | 2 | 6 | | | | | | | | | | | | |
| Q | B van de Zandschulp | 6$^5$ | 6$^4$ | 6 | 6 | 6 | Q | B van de Zandschulp | 4 | 4 | 7 | 6 | 4 | | | | | | | | | | | | |
| 19 | H Hurkacz | 7$^7$ | 7$^7$ | 2 | 2 | 4 | | | | | | | | | | | | | | | A Davidovich Fokina | 6 | 6 | 4 | 6 |
| 27 | F Fognini | 6 | 6 | 6 | | | | | | | | | | | | | | | | | F Delbonis | 4 | 4 | 6 | 4 |
| WC | G Barrère | 4 | 1 | 4 | | | 27 | F Fognini | 7$^8$ | 6 | 6 | | | | | | | | | | | | | | |
| | M Fucsovics | 6 | 6 | 7$^7$ | | | | M Fucsovics | 6$^6$ | 1 | 2 | | | | | | | | | | | | | | |
| | G Simon | 4 | 1 | 6$^5$ | | | | | | | | | | 27 | F Fognini | 4 | 1 | 3 | | | | | | | |
| | R Albot | 1 | 6 | 0 | 1 | | | | | | | | | | F Delbonis | 6 | 6 | 6 | | | | | | | |
| | F Delbonis | 6 | 2 | 6 | 6 | | | F Delbonis | 4 | 6 | 3 | 6 | 6 | | | | | | | | | | | | |
| | P Andújar | 4 | 5 | 6 | 6 | 6 | | P Andújar | 6 | 1 | 6 | 3 | 2 | | | | | | | | | | | | |
| 4 | D Thiem | 6 | 7 | 3 | 4 | 4 | | | | | | | | | | | | | | | | | | | |

#### Section 7

| First round | First round | First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Second round | Second round | Third round | Third round | Third round | Third round | Third round | Third round | Fourth round | Fourth round | Fourth round | Fourth round | Fourth round |
| 5 | S Tsitsipas | 7$^8$ | 6 | 6 | | | | | | | | | | | | | | | | | | | | |
| | J Chardy | 6$^6$ | 3 | 1 | | | 5 | S Tsitsipas | 6 | 6 | 6 | | | | | | | | | | | | | |
| | S Korda | 4 | 2 | 2 | | | | P Martínez | 3 | 4 | 3 | | | | | | | | | | | | | |
| | P Martínez | 6 | 6 | 6 | | | | | | | | | | 5 | S Tsitsipas | 5 | 6 | 7$^7$ | 6 | | | | | |
| Q | M Marterer | 4 | 1 | 6$^3$ | | | | | | | | | | 31 | J Isner | 7 | 3 | 6$^3$ | 1 | | | | | |
| | F Krajinović | 6 | 6 | 7$^7$ | | | | F Krajinović | 6$^6$ | 1 | 6$^5$ | | | | | | | | | | | | | |
| | S Querrey | 6$^2$ | 3 | 4 | | | 31 | J Isner | 7$^8$ | 6 | 7$^7$ | | | | | | | | | | | | | |
| 31 | J Isner | 7$^7$ | 6 | 6 | | | | | | | | | | | | | | | | 5 | S Tsitsipas | 6 | 6 | 7 |
| LL | F Cerúndolo | 3 | 4 | 3 | | | | | | | | | | | | | | | | 12 | P Carreño Busta | 3 | 2 | 5 |
| | T Monteiro | 6 | 6 | 6 | | | | T Monteiro | 3 | 7$^7$ | 6$^2$ | 6 | 3 | | | | | | | | | | | |
| | S Johnson | 6$^5$ | 3 | 6 | 6 | 6 | | S Johnson | 6 | 6$^2$ | 7$^7$ | 3 | 6 | | | | | | | | | | | |
| | F Tiafoe | 7$^7$ | 6 | 4 | 2 | 1 | | | | | | | | | S Johnson | 4 | 4 | 2 | | | | | | |
| | E Gerasimov | 6$^3$ | 4 | 3 | | | | | | | | | | 12 | P Carreño Busta | 6 | 6 | 6 | | | | | | |
| WC | E Couacaud | 7$^7$ | 6 | 6 | | | WC | E Couacaud | 6 | 3 | 4 | 4 | | | | | | | | | | | | |
| | N Gombos | 3 | 4 | 3 | | | 12 | P Carreño Busta | 2 | 6 | 6 | 6 | | | | | | | | | | | | |
| 12 | P Carreño Busta | 6 | 6 | 6 | | | | | | | | | | | | | | | | | | | | |

#### Section 8

| First round | First round | First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Second round | Second round | Third round | Third round | Third round | Third round | Third round | Third round | Fourth round | Fourth round | Fourth round | Fourth round | Fourth round |
| 16 | G Dimitrov | 6 | 6 | 5 | 0$^r$ | | | | | | | | | | | | | | | | | | | |
| | M Giron | 2 | 4 | 7 | 3 | | | M Giron | 7$^7$ | 6 | 6$^3$ | 6 | | | | | | | | | | | | |
| | G Pella | 6 | 7$^7$ | 7 | | | | G Pella | 6$^2$ | 1 | 7$^7$ | 4 | | | | | | | | | | | | |
| Q | DE Galán | 3 | 6$^4$ | 5 | | | | | | | | | | | M Giron | 1 | 7 | 2 | 2 | | | | | |
| | E Ruusuvuori | 6 | 3 | 6$^4$ | 3 | | | | | | | | | 22 | C Garín | 6 | 5 | 6 | 6 | | | | | |
| Q | M McDonald | 4 | 6 | 7$^7$ | 6 | | Q | M McDonald | 6 | 6 | 6$^7$ | 3 | 6 | | | | | | | | | | | |
| | JI Londero | 6 | 4 | 6$^6$ | 2 | | 22 | C Garín | 4 | 4 | 7$^9$ | 6 | 8 | | | | | | | | | | | |
| 22 | C Garín | 3 | 6 | 7$^8$ | 6 | | | | | | | | | | | | | | | 22 | C Garín | 2 | 1 | 5 |
| 32 | R Opelka | 6 | 6 | 6 | | | | | | | | | | | | | | | | 2 | D Medvedev | 6 | 6 | 7 |
| | A Martin | 3 | 2 | 4 | | | 32 | R Opelka | 6 | 6 | 3 | 7 | | | | | | | | | | | | |
| | J Munar | 6$^6$ | 6 | 7$^7$ | 6 | | | J Munar | 3 | 2 | 6 | 5 | | | | | | | | | | | | |
| | J Thompson | 7$^8$ | 1 | 6$^5$ | 4 | | | | | | | | | 32 | R Opelka | 4 | 2 | 4 | | | | | | |
| | T Paul | 6 | 6 | 4 | 4 | 10 | | | | | | | | 2 | D Medvedev | 6 | 6 | 6 | | | | | | |
| WC | C O'Connell | 2 | 4 | 6 | 6 | 8 | | T Paul | 6 | 1 | 4 | 3 | | | | | | | | | | | | |
| | A Bublik | 3 | 3 | 5 | | | 2 | D Medvedev | 3 | 6 | 6 | 6 | | | | | | | | | | | | |
| 2 | D Medvedev | 6 | 6 | 7 | | | | | | | | | | | | | | | | | | | | |

## Seeded players

The following are the seeded players. Seedings are based on ATP rankings as of 24 May 2021. Rankings and points before are as of 31 May 2021. Because the tournament was moved a week, points of the week of 10 June 2019 include results from Stuttgart and 's-Hertogenbosch.
As announced by the ATP in March 2021, tournaments from 4 March to 4 August 2019 points due to COVID ranking adjustments will count 50%, including their 2020 points whichever is greater. 2019 points which are higher will still be dropped as normal. Accordingly, the higher of each player's 2019 or 2020 points will be replaced by his 2021 points at the end of the tournament. Note that this is a different ranking adjustment system than the one being used by the WTA for the women's event.
| Seed | Rank | Player | Points before | 2019 points | 2020 points | Points won | Points after | Status |
| 1 | 1 | Novak Djokovic | 11,313 | 720 | 1,200 | 2,000 | 12,113 | Champion, defeated Stefanos Tsitsipas [5] |
| 2 | 2 | Daniil Medvedev | 9,793 | 10+10 | 10 | 360 | 10,143 | Quarterfinal lost to Stefanos Tsitsipas [5] |
| 3 | 3 | Rafael Nadal | 9,630 | 2,000 | 2,000 | 720 | 8,630 | Semifinal lost to Novak Djokovic [1] |
| 4 | 4 | Dominic Thiem | 8,445 | 1,200 | 360 | 10 | 7,425 | First round lost to Pablo Andújar |
| 5 | 5 | Stefanos Tsitsipas | 7,500 | 180+10 | 720 | 1,200 | 7,980 | Runner-up, lost to Novak Djokovic [1] |
| 6 | 6 | Alexander Zverev | 6,990 | 360 | 180 | 720 | 7,350 | Semifinals lost to Stefanos Tsitsipas [5] |
| 7 | 7 | Andrey Rublev | 6,090 | 0 | 360 | 10 | 5,910 | First round lost to Jan-Lennard Struff |
| 8 | 8 | Roger Federer | 5,605 | 720 | 0 | 180 | 5,065 | Fourth round withdrew due to physical condition concerns |
| 9 | 9 | Matteo Berrettini | 3,958 | 45+250 | 90 | 360 | 4,103 | Quarterfinal lost to Novak Djokovic [1] |
| 10 | 10 | Diego Schwartzman | 3,465 | 45 | 720 | 360 | 3,105 | Quarterfinals lost to Rafael Nadal [3] |
| 11 | 11 | Roberto Bautista Agut | 3,215 | 90 | 90 | 45 | 3,170 | Second round lost to Henri Laaksonen [Q] |
| 12 | 12 | Pablo Carreño Busta | 3,085 | 90 | 360 | 180 | 2,905 | Fourth round lost to Stefanos Tsitsipas [5] |
| 13 | 13 | David Goffin | 2,875 | 90+45 | 10 | 10 | 2,830 | First round lost to Lorenzo Musetti |
| 14 | 15 | Gaël Monfils | 2,713 | 180+20 | 10 | 45 | 2,568 | Second round lost to Mikael Ymer |
| 15 | 16 | Casper Ruud | 2,690 | 90 | 90 | 90 | 2,690 | Third round lost to Alejandro Davidovich Fokina |
| 16 | 17 | Grigor Dimitrov | 2,521 | 90 | 180 | 10 | 2,431 | First round retired against Marcos Giron |
| 17 | 18 | Milos Raonic | 2,518 | 0+90 | 0 | 0 | 2,473 | Withdrew for personal reasons |
| 18 | 19 | Jannik Sinner | 2,500 | (48)$^†$ | 360 | 180 | 2,320 | Fourth round lost to Rafael Nadal [3] |
| 19 | 20 | Hubert Hurkacz | 2,498 | 10 | 10 | 10 | 2,533 | First round lost to Botic van de Zandschulp [Q] |
| 20 | 21 | Félix Auger-Aliassime | 2,423 | 0+150 | 10 | 10 | 2,423 | First round lost to Andreas Seppi |
| 21 | 22 | Alex de Minaur | 2,350 | 45+45 | 10 | 45 | 2,350 | Second round lost to Marco Cecchinato |
| 22 | 23 | Cristian Garín | 2,350 | 45+45 | 90 | 180 | 2,440 | Fourth round lost to Daniil Medvedev [2] |
| 23 | 25 | Karen Khachanov | 2,280 | 360+10 | 180 | 45 | 2,010 | Second round lost to Kei Nishikori |
| 24 | 26 | Aslan Karatsev | 2,245 | (18)$^†$ | 16 | 45 | 2,274 | Second round lost to Philipp Kohlschreiber [PR] |
| 25 | 27 | Dan Evans | 2,195 | 10+125 | 10 | 10 | 2,106 | First round lost to Miomir Kecmanović |
| 26 | 28 | Lorenzo Sonego | 2,132 | 10 | 180 | 10 | 2,042 | First round lost to Lloyd Harris |
| 27 | 29 | Fabio Fognini | 1,933 | 180 | 10 | 90 | 1,843 | Third round lost to Federico Delbonis |
| 28 | 31 | Nikoloz Basilashvili | 1,785 | 10+10 | 10 | 45 | 1,820 | Second round lost to Carlos Alcaraz [Q] |
| 29 | 32 | Ugo Humbert | 1,780 | 10 | 10 | 10 | 1,815 | First round lost to Ričardas Berankis |
| 30 | 33 | Taylor Fritz | 1,760 | 45 | 90 | 45 | 1,715 | Second round lost to Dominik Koepfer |
| 31 | 34 | John Isner | 1,730 | 0 | 45 | 90 | 1,775 | Third round lost to Stefanos Tsitsipas [5] |
| 32 | 35 | Reilly Opelka | 1,726 | 10 | 10 | 90 | 1,806 | Third round lost to Daniil Medvedev [2] |
† The player did not qualify for the tournament in 2019. Therefore, this represents his points from the 2019 ATP Challenger Tour.

### Withdrawn players

The following players would have been seeded, but withdrew before the tournament began.
| Rank | Player | Points before | 2019 points | 2020 points | Points lost | Points after | Withdrawal reason |
| 14 | Denis Shapovalov | 2,780 | 10 | 45 | – | 2,780 | Shoulder injury |
| 24 | Stan Wawrinka | 2,281 | 360 | 90 | 315 | 1,966 | Foot injury |
| 30 | Borna Ćorić | 1,870 | 90+90 | 10 | 112 | 1,758 | Shoulder surgery |

## Other entry information
### Wild cards

The following players were awarded wild cards into the main draw.
* Grégoire Barrère
* Benjamin Bonzi
* Mathias Bourgue
* Arthur Cazaux
* Enzo Couacaud
* Hugo Gaston
* Christopher O'Connell
* Arthur Rinderknech

### Protected ranking

* Philipp Kohlschreiber (96)
* Lu Yen-hsun (71)
* Kamil Majchrzak (105)

### Qualifiers

* Carlos Alcaraz
* Jenson Brooksby
* Taro Daniel
* Bjorn Fratangelo
* Daniel Elahi Galán
* Alessandro Giannessi
* Denis Istomin
* Henri Laaksonen
* Maximilian Marterer
* Mackenzie McDonald
* Oscar Otte
* Roman Safiullin
* Carlos Taberner
* Mario Vilella Martínez
* Botic van de Zandschulp
* Bernabé Zapata Miralles

### Lucky losers

* Francisco Cerúndolo
* Peter Gojowczyk

### Withdrawals
#### Before the tournament

* Nick Kyrgios (57) → replaced by Facundo Bagnis (103)
* Borna Ćorić (26) → replaced by Andrej Martin (104)
* Kyle Edmund (69) → replaced by Roberto Carballés Baena (105)
* Stan Wawrinka (20) → replaced by Kamil Majchrzak (105 PR)
* Attila Balázs (102) → replaced by João Sousa (106)
* Vasek Pospisil (64) → replaced by Kevin Anderson (107)
* Denis Shapovalov (13) → replaced by Yasutaka Uchiyama (108)
* Milos Raonic (19) → replaced by Francisco Cerúndolo (LL)
* John Millman (44) → replaced by Peter Gojowczyk (LL)

#### During the tournament

* Roger Federer

### Retirements

* Grigor Dimitrov
* Henri Laaksonen
* Lorenzo Musetti

## Explanatory notes

* ↑ Last direct acceptance