# U.S. Route 78 in Arkansas

U.S. Highway 78 (US 78) is an east–west highway in northeast Arkansas. The road largely runs concurrently with Interstate 55 (I-55) within the state.

## Route description
### Western terminus to Blytheville

US 78 begins at interchange with I-57/US 67 at exit 102 near Swifton where the roadway continues as AR 226 west toward Swifton. US 78/AR 226 then intersects Arkansas Highway 18 (AR 18) just south of the Cash Central Business District. The two highways then have an intersection with AR 226 southwest of Gilkerson before beginning to run concurrently with US 49 and US 63 east-northeast of Gibson. AR 226 then leaves US 49/US 63/US 78 in Jonesboro. Still in the city limits of Jonesboro, US 49/US 78 then meets I-555/AR 18; this is the point where US 63 splits from US 49/US 78, while US 49/US 78 begins to run concurrently with I-555. I-555/US 49/US 78 then intersects AR 1B (Harrisburg Road). I-555/US 78 then has an interchange in Jonesboro; it serves AR 1 (Stadium Boulevard/Red Wolf Boulevard) and Caraway Road. After meeting AR 463 and Nettleton Avenue, US 78 then splits from I-555 at exit 39. About 1.21 miles (1.95 km) down the road, US 78 meets AR 18 again, this time the two highways run concurrently to Blytheville.
US 78/AR 18 intersects AR 158 and AR 135 in Lake City. US 78/AR 18 then passes through the communities of Black Oak, Monette, Leachville, Manila, Wilson Junction, Dell, and finally Blytheville. In Blytheville, US 78/AR 18 intersects AR 151, US 61, AR 239, and I-55. At I-55, US 78 ends its concurrency with AR 18; US 78 travels concurrently with I-55 south to Memphis, Tennessee, while AR 18 continues straight towards Armorel.

### Blytheville to Tennessee state line
## History

Prior to November 2023, US 78 formerly ended at US 64/US 70/US 79 (Second Street) in Memphis, Tennessee. On October 25, 2023, the Arkansas Highway Commission voted unanimously to extend the US 78 designation into northeast Arkansas. According to the Arkansas Department of Transportation (ARDOT), the US 78 designation would be extended along several other routes from its former western terminus in Memphis across the Memphis & Arkansas Bridge to its newer current western terminus near Swifton, Arkansas, at US 67 (before I-57 was designated at that time). The route would be cosigned along portions of US 64, US 70, US 79, I-55, US 61, I-40, AR 18, AR 18S, I-555, US 49, US 63, and AR 226. This extension of the US 78 route designation was seen as a way to boost economic growth in the region by assigning a single route number for travelers to follow. The extension was approved by the American Association of State Highway and Transportation Officials (AASHTO) in November 2023.

## Major intersections

| County | Location | Exit | Destinations | Notes |
| Craighead | ​ | | I-57 / US 67 / AR 226 west – Swifton, St. Louis, Little Rock | Western terminus of US 78; western end of AR 226 concurrency; roadway continues as AR 226 westbound; AR 226 west is the former US 67 north; exit 102 on I-57/US 67 |
| Craighead | Cash | | AR 18 to AR 91 – Grubbs | |
| Craighead | ​ | | AR 349 north to AR 91 | |
| Craighead | ​ | | US 49 south / US 63 – Waldenburg | Western end of US 49/US 63 concurrency |
| Craighead | Jonesboro | | AR 226 east (Woodsprings Road) | Eastern end of AR 226 concurrency |
| Craighead | Jonesboro | 45 | I-555 north / US 63 north / AR 18 – Jonesboro | Eastern end of US 63 concurrency; western end of I-555 concurrency |
| Craighead | Jonesboro | 44 | AR 1B (Harrisburg Road) | |
| Craighead | Jonesboro | 42 | US 49 north / AR 1 (Stadium Boulevard / Red Wolf Boulevard) / Caraway Road – Jonesboro, Paragould | Eastern end of US 49 concurrency |
| Craighead | Jonesboro | 40 | AR 463 south (Nettleton Avenue) | Northern terminus of AR 463 |
| Craighead | Jonesboro | 39 | I-555 south / AR 18S begins (Dr. Martin Luther King Drive) – Memphis | Eastern end of I-555 concurrency; southern terminus of AR 18S; western end of SR 18S concurrency |
| Craighead | Jonesboro | | AR 18 west (Highland Avenue) / AR 18S ends (Dr. Martin Luther King Drive) – Memphis | Northern terminus of AR 18S; eastern end of AR 18S concurrency; western end of AR 18 concurrency |
| Craighead | Lake City | | AR 158 west – Lunsford | Eastern terminus of AR 158 |
| Craighead | Lake City | | AR 135 north – Paragould | Southern terminus of AR 135 |
| Craighead | Black Oak | | AR 135 south – Caraway, Lepanto | Northern terminus of AR 135 |
| Craighead | Monette | | AR 139 north (Edmonds Street) | Southern terminus of AR 139 |
| Craighead | Monette | | AR 139 south – Caraway | Northern terminus of AR 139 |
| Mississippi | Leachville | | AR 119 north to AR 119 – Leachville | Southern terminus of AR 119 |
| Mississippi | Manila | | AR 18B east (West Lake Street) – Manila Business District | Western terminus of AR 18B; former AR 77 |
| Mississippi | Manila | | AR 77 north – Leachville | Western end of AR 77 concurrency |
| Mississippi | Manila | | AR 181 south – Athelstan | Northern terminus of AR 181 |
| Mississippi | ​ | | AR 181 south – Victoria | Northern terminus of AR 181 |
| Mississippi | Dell | | AR 77 south – Dell Business District | Eastern end of AR 77 concurrency |
| Mississippi | ​ | | AR 312 east | Western terminus of AR 312 |
| Mississippi | ​ | | AR 239 north – Half Moon | Southern terminus of AR 239 |
| Mississippi | Blytheville | | AR 151 north – Gosnell | Southern terminus of AR 151 |
| Mississippi | Blytheville | | US 61 (Division Street) to I-55 – Blytheville Business District | |
| Mississippi | Blytheville | | AR 239 south (Ruddle Street) | Northern terminus of AR 239 |
| Mississippi | Blytheville | 67 | I-55 north / AR 18 east – Armorel, St. Louis | Eastern end of SR 18 concurrency; western end of I-55 concurrency |
| see I-55 (mile 0.000–67.079) |||||||
| Mississippi River | Mississippi River | | I-55 south / US 61 south / US 64 east / US 70 east / US 78 east / US 79 north / SR 1 east – Memphis, Jackson, MS | Continuation into Tennessee; western terminus of SR 1 |
| 1.000 mi = 1.609 km; 1.000 km = 0.621 mi Concurrency terminus |||||||