OpenLLM-France/wikimedia huggingface dataset:
# Braun's lipoprotein

Braun's lipoprotein (BLP, Lpp, murein lipoprotein, or major outer membrane lipoprotein) was first identified by V. Braun and K. Rehn in 1969, it was the first Lipoprotein identified prompting much further study in this area. It is found in some gram-negative cell walls, is one of the most abundant membrane proteins; its molecular weight is about 7.2 kDa. It is bound at its C-terminal end (a lysine) by a covalent bond to the peptidoglycan layer (specifically to diaminopimelic acid molecules) and is embedded in the outer membrane by its hydrophobic head (a cysteine with lipids attached). BLP tightly links the two layers and provides structural integrity to the outer membrane.

## Characteristics

The gene encoding Braun's lipoprotein initially produces a protein composed of 78 amino acids, which includes a 20 amino acid signal peptide at the amino terminus. The mature protein is 6 kDa in size. Three monomers of Lpp assemble into a leucine zipper coiled-coil trimer.
Large amounts of Braun's lipoprotein is present, more than any other protein in E. coli. Unlike other lipoproteins, it is linked covalently to the peptidoglycan. Lpp connects the outer membrane to the peptidoglycan. Lpp is anchored to the outer membrane by its amino-terminal lipid group. In E. coli, one third of Lpp proteins form a peptide bond via the side chain of its carboxy-terminal lysine with diaminopimelic acid in the peptidoglycan layer. The rest of the Lpp molecules are present in a "free" form unlinked to peptidoglycan. The free form is exposed on the surface of E. coli.

## Functions

Lpp, along with another OmpA-like lipoprotein called Pal/OprL (P0A912), maintains the stability of the cell envelope by attaching the outer membrane to the cell wall.
Lpp has been proposed as a virulence factor of Yersinia pestis, the cause of plague. Y. pestis needs lpp for maximum survival in macrophages and to efficiently kill mouse models of bubonic and pneumonic plague.

## Immunology

Braun's lipoprotein binds to the pattern recognition receptor TLR2. Lpp induces adhesion of neutrophils to human endothelial cells by activating the latter.
# The Plex

The Plex is a 2008 Australian film directed by Tim Boyle and starring Matt Doran, Jason Crewes and Samantha Turner. The film premiered on 4 September 2008.

## Synopsis

AJ lives an unsatisfactory life as an usher at the local Multiplex cinema working alongside his best friend Zeke and his sexy, but power hungry girlfriend Katie. After AJ is unfairly fired he decides to get even with his old boss.

## Cast

* Laura Andersen as Betty Parker
* Steve Bastoni as The Baron / Mad Morgan Edwards
* John Boxer as Angus Vasnar
* Gerard Boyle as Single Guy
* Tim Boyle as A.D.D. Dave
* Andrew Caryofyllis as Allan Smithee
* Peter Chapman as Change Guy
* Brian Cobb as Hollywood Sam
* Michael Cotton-Stapleton as Sebastian
* Jason Crewes as Zeke Edwards
* Leo Domigan as Frank Stone
* Matt Doran as AJ Stone
* Gabriel Egan as Blinger
* Adam Gelin as Donations Man
* Salme Geransar as Misty
* Simon T. Gleeson as Stefan
* Shaun Angus Hall as Sci Fi Movie Freak
* Tori Hartigan as Bec
* Stella Ha Vi Do as Japanese Woman
* Damion Hunter as Mac
* Mark Jensen as Mr. Carbonie
* John Schwarz as Vincent Vasnar
* Tai Scrivener as Keith
* Yvonne Strahovski as Sarah
* Samantha Turner as Kat
* Alys Daroy as Voice of Sarah (Yvonne Strahovski)
# Age determination in dinosaurs

Age determination in dinosaurs is mainly used to determine the approximate age of a dinosaur when the animal died.

## History

Early attempts to estimate the longevity of dinosaurs used allometric scaling principles. Ages were determined by dividing individual mass estimates by rates of growth for similar, extant taxa. For very large individuals, growth rates were extrapolated to dinosaur proportions using regression analysis. The results of these investigations have been extremely variable as they depend on mass estimates and growth rates that are highly at odds with one another.
For example, longevity estimates for the sauropod Hypselosaurus priscus range from a few decades to several hundred years. However, it has been shown that most dinosaur bones have growth lines that are visible in thin sectioned material viewed under a polarized light source.

## Growth lines

Two types of growth lines exist: annuli, and lines of arrested growth (LAGs). Histological examinations have revealed that annuli are composed of thin layers of avascular bone with parallel-aligned bone fibers. The growth line annuli are found compressed between broad vascularized regions of bone with randomly oriented fibrillar patterns, known as zones.
Lines of arrested growth, similar to annuli, are found between zones are avascular. They are, however, much thinner, and have relatively fewer bone fibers by volume.
Studies on extant vertebrates indicate that the vascularized zones form during moderate to rapid skeletogenesis, and that abrupt metabolic disruptions of bone formation can trigger growth line deposition.
Both types of growth lines may be deposited in synchrony with endogenous biorhythms. For example, captive crocodilians exposed to constant temperature, diet, and photoperiod, still exhibit the periodic and cyclical skeletal growth banding of their wild counterparts. Consequently, it is assumed by many paleontologists that the growth lines of dinosaurs reflect annual rhythms, and that they may be used to determine individual ages. However, in the large and long bones of many dinosaurian taxa, resorption of internal and external bone proceeds even as new cortical bone continues to be deposited, so that growth lines deposited early in development may need to be inferred.

## Results in dinosaurs

The results of pioneering efforts to age dinosaur fossils using growth ring counts suggest that the longevity of the basal ceratopsian Psittacosaurus mongoliensis was 10 or 11 years. The prosauropod Massospondylus carinatus 15 years of age, the sauropods Lapparentosaurus and Narindasaurus 43 years, the coelophysoid Megapnosaurus rhodesiensis 7 years, and the maniraptor Troodon formosus 3-5 years of age respectively. These data are being used in conjunction with mass estimated in order to infer the metabolic status and growth rates of dinosaurs.
# NBA ShootOut 2001

NBA ShootOut 2001 is a 2000 basketball video game developed by Killer Game and published by Sony Computer Entertainment for the PlayStation. A port developed by 989 Sports for the PlayStation 2 was released in 2001. Chris Webber is featured on the game's cover.

## Reception

Aggregate score :
| Aggregator | Score | Score |
| Aggregator | PS | PS2 |
| Metacritic | 71/100 | 54/100 |
Review scores :
| Publication | Score | Score |
| Publication | PS | PS2 |
| AllGame | | N/A |
| Electronic Gaming Monthly | 5.83/10 | 4.67/10 |
| Game Informer | 5.5/10 | 6.5/10 |
| GamePro | | N/A |
| GameRevolution | N/A | D |
| GameSpot | 6.7/10 | 6.8/10 |
| GameSpy | 82% | N/A |
| IGN | 6.3/10 | 6/10 |
| Official U.S. PlayStation Magazine | | |
| PlayStation: The Official Magazine | 4/10 | 5/10 |
| The Cincinnati Enquirer | N/A | |
The game received "mixed or average reviews" on both platforms according to the review aggregation website Metacritic.
# UK Kidney Association

The UK Kidney Association (UKKA), formerly the Renal Association, is the second oldest nephrology society in the world. The UKKA has over 1,400 doctors, scientists and multi-professional team members.

## History

It was founded in 1950 by Arthur Arnold Osman and first met on March 30, 1950, it is the second nephrology society in the world after the Société de Pathologie Rénale, which met in Paris in February 1949. For 71 years, the association has promoted and shared research on kidney disease.
The Renal Association established the UK Renal Registry (UKRR) in 1995. The UKRR team manage data collection, analysis and reporting on approximately 8,000 new patients, 67,000 existing patients on RRT and on about 500,000 patients with an acute kidney injury each year. Data collated from renal centres and hospital laboratories is used to improve the care of patients with kidney disease across the UK.
In 2005 the association, together with the Royal College of Physicians of London, published national guidelines on the diagnosis and management of chronic kidney disease (CKD), which led to the routine reporting of the estimated glomerular filtration rate (eGFR) by most National Health Service laboratories.

## Activities

The Renal Association has continued to produce clinical practice guidance on the management of patients with kidney disease since 1995. The guidelines are not funded by any external organisation, commercial company or charity. The guidelines have been accredited by the National Institute for Health and Care Excellence (NICE).
As a membership organisation, the association supports all professionals involved in the care of patients with kidney disease and works with partners to enhance education, training and research.
The association works closely with the Kidney Quality Improvement Partnership (KQuIP), the British Association of Paediatric Nephrology, the UK Renal Pharmacy Group, and RaDaR, the rare kidney disease registry.
In April 2021 the British Renal Society and the Renal Association merged to create the UK Kidney Association, a new organisation dedicated to supporting the whole multi-professional team (MPT) in the delivery of kidney care, education and research.
# Siege of Mytilene (81 BC)

The siege of Mytilene took place in 81 BC during the Second Mithridatic War, when the city of Mytilene on the island of Lesbos was taken by Rome. It was the first documented military action of Julius Caesar.
Mytilene, the capital city of the island of Lesbos in the Aegean Sea, revolted against Rome during the First Mithridatic War and was suspected of actively or tacitly aiding pirates in the region. The island did not surrender at the end of the war, so the reprisal operations were carried during the Second Mithridatic War. Suetonius credits Marcus Minucius Thermus, the governor of the Roman Asia province, with the victory, but the siege may have been conducted by or in coordination with Lucius Licinius Lucullus.
Julius Caesar began his military service during the siege after his pardon by Sulla during the proscriptions of 82 BC. It was during the siege that Caesar was awarded the Civic Crown, a considerable honour in the Roman military, which is a title awarded to a Roman soldier who saves the life of a fellow citizen.
# Holiday (2023 film)

Holiday is a 2023 Italian coming-of-age drama film directed and co-written by Edoardo Gabbriellini
The film premiered in the Centrepiece program at the 2023 Toronto International Film Festival.

## Plot

Veronica was the subject of a lengthy trial and served two years in prison for the alleged murder of her mother and her mother's lover. She is declared innocent and released from prison just before her 20th birthday. In a small town on the Ligurian Riviera, Veronica searches for a new lease on life after having her young adult life put on hold. Supported by her friend Giada and her father, Veronica maintains her innocence, but her newfound public notoriety presents challenges.

## Cast

* Margherita Corradi as Veronica
* Giorgia Frank as Giada
* Alessandro Tedeschi as Veronica's father
* Alice Arcuri as Veronica's mother
* Alessia Giuliani as Simona
* Flavio Furno as Public Prosecutor
* Massimo Mesciulam as Lieutenant
* Alessio De Persio as Defense Attorney
* Alessio Raffaghelli as Nicola Guarneri
* Francesca Maselli as Giada's Mother
* Anna Argenti as Friend
* Asia Spina as Friend

## Production

Edoardo Gabbriellini wrote the film's screenplay with Carlo Salsa. It is based on a story by Gabbriellini, Salsa and Michele Pellegrini. It was produced by Cinemaundici and Vision Distribution, in collaboration with The Apartment Pictures and Frenesy Film Company.

## Release

Holiday was selected to be screened in the Centrepiece program at the 48th Toronto International Film Festival, where it had its world premiere on 8 September 2023. It was also invited at the 18th Rome Film Festival, where it was screened in October 2023.
Europictures distributed the film in a "special event" at cinemas only on 23, 24, and 25 October 2023.
# Mouna Daaham

Mouna Daaham is a 1990 Indian Malayalam film, directed by K. Radhakrishnan. The film has musical score by S. P. Venkatesh. It was awarded an A (restricted to adults) certificate by the censor board.

## Cast

* Harish Kumar
* Kalaiselvi
* Prathapachandran
* Nizhalgal Ravi
* Syamala

## Soundtrack

The music was composed by Sangeetharajan and the lyrics were written by Poovachal Khader.
| No. | Song | Singers | Lyrics | Length (m:ss) |
| 1 | "Ee Raavil" | Unni Menon | Poovachal Khader | |
| 2 | "Nillu Nillu Penne" | Unni Menon | Poovachal Khader | |
# Cyromazine

Cyromazine is a triazine insect growth regulator used as an insecticide to control dipterans and some other insects. It is a cyclopropyl derivative of melamine. The exact mechanism of action of cyromazine against insects is unclear although it does affect the larval and pupal cuticles.
In veterinary medicine, cyromazine is used as an ectoparasiticide. It has been used since 1979 in Australia and New Zealand to control and prevent flystrike of sheep by blowfly. The exact mechanism of action has not been determined, but it is non-toxic to mammals and does not target the nervous system. It is not toxic to adult flies, only having its effect on larval forms by disrupting the moulting process. It can give 8-10 weeks protection when applied topically. Because of this it has little effect on existing infestations and is commonly used prophylactically. In 2011 resistance was detected in Lucilia cuprina to cyromazine from infested sheep that failed to be protected following treatment.

## Regulation

The Food Safety and Inspection Service (FSIS) of the United States Department of Agriculture (USDA) provides a test method for analyzing cyromazine and melamine in animal tissues in its Chemistry Laboratory Guidebook which "contains test methods used by FSIS Laboratories to support the Agency's inspection program, ensuring that meat, poultry, and egg products are safe, wholesome and accurately labeled." In 1999, in a proposed rule published in the Federal Register regarding cyromazine residue, the United States Environmental Protection Agency (EPA) proposed "remov[ing] melamine, a metabolite of cyromazine from the tolerance expression since it is no longer considered a residue of concern."
# Shila Ahmed

Shila Ahmed (Bengali: শিলা আহমেদ) is a former Bangladeshi television and film actress. She won Bangladesh National Film Award for Best Child Artist Award for her performance in Aguner Poroshmoni (1994).

## Early life and career

Ahmed was born to writer Humayun Ahmed and Gultekin Khan.
Ahmed was involved in acting in television from her childhood. She is notable for her role in television dramas such as Kothao Keu Nei, Aaj Robibar and Nokkhotrer Raat.

## Personal life

Shila married her friend Apu and had two children. Later, they were divorced and she married Asif Nazrul, a professor of Department of Law at the University of Dhaka in 2013. They have a daughter together.

## Works
### Television

| Year | TV Series/TV film | Role |
| 1993-1994 | Kothao Keu Nei | Child artist (Lina) |
| 1992 | Priyo Podorekha | Child artist (Bilu) |
| 1995 | Oija Board | Child artist (Nila) |
| 1995 | Neem Ful | Child artist |
| 1997 | Nokkhotrer Raat | Child artist (Polin) |
| 1999 | Aaj Robibar | Teenager (Konka) |
| 2002 | Kuabnagar | Teenager (Khuab Konya) |

### Films

| Year | TV Series/TV film | Role | Comment |
| 1994 | Aguner Poroshmoni | Child artist (Apala) | |
# Broom Fell

Broom Fell is a small hill in the English Lake District. It lies on a ridge connecting Lord's Seat and Graystones, but it is rarely climbed. Alfred Wainwright did, however, accord it the status of a separate fell in his influential guidebook series, the Pictorial Guide to the Lakeland Fells.

## Topography

The North Western Fells occupy the area between the rivers Derwent and Cocker, a broadly oval swathe of hilly country, elongated on a north–south axis. Two roads cross from east to west, dividing the fells into three convenient groups. The most northerly sector, rising between Whinlatter Pass and the Vale of Embleton, includes Broom Fell.
Lord's Seat, is the highest of the fells north of Whinlatter and sends out a long ridge westwards. The ridge begins with a marshy depression before rising to the summit of Broom Fell. It then continues west to the more pronounced saddle of Widow Hause, beyond which is Graystones. Widow Hause, is densely forested on the southern side with the conifers of the Darling How Plantation.
To the south of Broom Fell, is the pleasant valley of Aiken Beck, heavily wooded in its lower reaches. This secluded dale lies between the main ridge and Whinlatter Fell, draining to the west and ultimately reaching the Cocker. Hidden within the Darling How Plantation, is the fine waterfall of Spout Force.
On the northern flank of Broom Fell, is Burthwaite Heights (1,043 ft), listed as a separate top in some guidebooks. This is a small hill beside the vast morass of Wythop. Wythop Moss itself lies to the west and drains (slowly) via Tom Rudd Beck. To the east of Burthwaite Heights, runs the valley of Wythop Beck, emptying rather more effectively between the twin hills of Ling Fell and Sale Fell.

## Geology

The predominant rock is the Ordovician Kirk Stile Formation of the Skiddaw Group. This consists of laminated mudstone and siltstone. To the south of the summit are outcrops of greywacke sandstone.

## Summit

The top is grassy, and the summit is marked by the end of a wall coming up from Aiken Beck to the southwest. Since this wall connects to no others, and simply stops at the highest point, its purpose is unknown. A summit cairn of approximately 2m in height now exists on the summit as does a small wind shelter made from part of the wall.
The view southward takes in the Whiteside-Grisedale Pike ridge and the Grasmoor fells showing behind. Westward, across the Vale of Lorton, are the Loweswater Fells, and to the east and north there are sightings of higher fells on either side of Lord's Seat. The coastal plain and Solway Firth are also seen to good effect.

## Ascents

From Wythop Mill a crossing of Wythop Moss can be made, using the old path which gives the only remotely dry footing. Once the marsh is passed an ascent up the northern slope of Widow Hause leads to the ridge.
The alternative is to make use of Aiken Beck, a car park being available near Scawgill Bridge on the Whinlatter Pass road. From the valley the southern slopes of Broom Fell can be tackled direct, or a longer route can be taken via the summit of Lord's Seat.
# Chilvers Coton

Chilvers Coton is an area of the town of Nuneaton in Warwickshire, England, around one mile south of the town centre.
Chilvers Coton was historically a village and civil parish in its own right and was mentioned in the Domesday Book of 1086 as “Celverdestoche,”. The author Mary Ann Evans (better known as George Eliot) lived at Griff House in the parish between 1820 and 1841. Chilvers Coton was the inspiration for the fictional village of Shepperton in Eliot's novel Scenes of Clerical Life. Like neighbouring Nuneaton, Chilvers Coton historically was a centre for the weaving and coal mining industries.
The parish of Chilvers Coton was made a local board district in 1850, being the area's first modern form of local government; prior to that it was governed by its vestry. The two local boards for Chilvers Coton and neighbouring Nuneaton were merged in 1893. The following year, all such districts were converted into urban districts. The Nuneaton and Chilvers Coton Urban District was elevated to become a municipal borough in 1907 under the single name of Nuneaton. The civil parish of Chilvers Coton continued to exist until 1920, but as an urban parish it had no parish council. The parish was abolished in 1920 when the parish of Nuneaton was enlarged to match the borough. In 1911 the parish had a population of 10,492.
The original Church of England parish church for the area is All Saints' Church. This church dated from the 13th century with 19th century additions. Most of the church, except the tower, was destroyed in the Second World War during a German air raid on Nuneaton, and was subsequently rebuilt during 1946-51 by German prisoners of war. A Roman Catholic church, Our Lady of the Angels is also located in the area, as well as a Methodist chapel.
Between 1850 and 1965, Chilvers Coton was served by its own railway station on the Coventry to Nuneaton Line. The Coventry Canal also runs through the area.
# Newton Investment Management

Newton Investment Management is a investment management firm based in London. It is subsidiary of BNY Investments.

## History

The firm was founded as Newton in 1978 as a joint venture with Scottish insurance broker Reed Stonehouse. In 1986, it was acquired by alexander & alexander and was renamed to Newton Investment Management. In 1992, the firm did a management buyout of alexander & alexander's stake. In 1994, it acquired Capital House group of companies from the Royal Bank of Scotland, with the bank acquiring a 33% interest in Newton Investment Management.
In 1998, Mellon Bank (now BNY) acquired 75% of Newton Investment Management for $277 million and in 2002, acquired the remaining interest.
# Saint Clare (film)

Saint Clare is a 2024 American comedy horror thriller film written by Mitzi Peirone and Guinevere Turner, directed by Peirone and starring Bella Thorne, Rebecca De Mornay, Ryan Phillippe, and Frank Whaley. It is based on the novel Clare At 16 by Don Roff.

## Premise

To the world, sixteen-year-old Clare Bleecker appears to be a normal teenager: a Catholic school student, an animal lover and devout vegan living with her grandparents. But like the small town she lives in, Clare is more than she appears to be. Underneath her reserved appearance lives a sociopath with dissociative identity disorder - a serial killer.

## Cast

* Bella Thorne as Clare Bleecker
* Ryan Phillippe as Timmons
* Rebecca De Mornay
* Frank Whaley as Mailman Bob
* Bart Johnson as Joe and Randall
* Dylan Flashner as Wade
* Jan Luis Castellanos as Truman

## Production

In January 2019, Deadline reported that Madelaine Petsch would play the titular character and also executive-produce the film. However, in May 2022, Bella Thorne was announced to replace Petsch in the lead role after Petsch signed on to star in The Strangers: Chapter 1, causing her to drop out of the project.
In August 2022, it was announced that the film was in postproduction and had been re-titled to Saint Clare.
# Gillam Airport

Gillam Airport (IATA: YGX, ICAO: CYGX) is located adjacent to Gillam, Manitoba, Canada.

## Airlines and destinations

| Airlines | Destinations |
| Calm Air | Churchill, Thompson, Winnipeg |