# 2016 Open Harmonie mutuelle – Singles

Nicolas Mahut was the defending champion, but chose not to defend his title.
Alexandre Sidorenko won the title, defeating Igor Sijsling 2–6, 6–3, 7–6$^{(7–3)}$ in the final.

## Seeds

* Jan-Lennard Struff (second round)
* Daniel Evans (quarterfinals)
* Karen Khachanov (second round)
* Luca Vanni (first round)
* Vincent Millot (first round)
* Igor Sijsling (final)
* Egor Gerasimov (first round)
* Quentin Halys (first round)

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Semifinals | Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final | Final | Final |
| WC | Alexandre Sidorenko | 3 | 6 | 6 | | | | | |
| | Aleksandr Nedovyesov | 6 | 3 | 0 | | | | | |
| | Aleksandr Nedovyesov | 6 | 3 | 0 | WC | Alexandre Sidorenko | 2 | 6 | 7$^7$ |
| | | | | | 6 | Igor Sijsling | 6 | 3 | 6$^3$ |
| WC | Gleb Sakharov | 6 | 5 | 4 | 6 | Igor Sijsling | 6 | 3 | 6$^3$ |
| 6 | Igor Sijsling | 3 | 7 | 6 | | | | | |

### Top half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 1 | J-L Struff | 6 | 6 | | | | | | | | | | | | | | | | |
| Q | S Doumbia | 4 | 4 | | 1 | J-L Struff | 1 | 4 | | | | | | | | | | | |
| | R Ramanathan | 6$^7$ | 1 | | | T Kamke | 6 | 6 | | | | | | | | | | | |
| | T Kamke | 7$^9$ | 6 | | | | | | | | T Kamke | 6 | 3 | 3 | | | | | |
| WC | M Teixeira | 5 | 3 | | | | | | | WC | A Sidorenko | 3 | 6 | 6 | | | | | |
| | A Karatsev | 7 | 6 | | | A Karatsev | 4 | 2 | | | | | | | | | | | |
| WC | A Sidorenko | 7$^7$ | 4 | 6 | WC | A Sidorenko | 6 | 6 | | | | | | | | | | | |
| 7 | E Gerasimov | 6$^4$ | 6 | 1 | | | | | | | | | | | WC | A Sidorenko | 3 | 6 | 6 |
| 3 | K Khachanov | 6 | 6 | | | | | | | | | | | | | A Nedovyesov | 6 | 3 | 0 |
| WC | TK Wang | 3 | 4 | | 3 | K Khachanov | 4 | 3 | | | | | | | | | | | |
| | G Žemlja | 6$^3$ | 1 | | | A Nedovyesov | 6 | 6 | | | | | | | | | | | |
| | A Nedovyesov | 7$^7$ | 6 | | | | | | | | A Nedovyesov | 6 | 6 | | | | | | |
| | F Gaio | 3 | | | | | | | | | F Gaio | 3 | 1 | | | | | | |
| Q | A Beck | 1$^r$ | | | | F Gaio | 6 | 3 | 7$^7$ | | | | | | | | | | |
| Q | R Boutillier | 3 | 6 | 6 | Q | R Boutillier | 4 | 6 | 6$^4$ | | | | | | | | | | |
| 8 | Q Halys | 6 | 3 | 4 | | | | | | | | | | | | | | | |

### Bottom half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 5 | V Millot | 5 | 4 | | | | | | | | | | | | | | | |
| | G Barrère | 7 | 6 | | | G Barrère | 6 | 6 | | | | | | | | | | |
| | C Lestienne | 6 | 7$^7$ | | | C Lestienne | 4 | 3 | | | | | | | | | | |
| | M Chazal | 1 | 6$^2$ | | | | | | | G Barrère | 4 | 2 | | | | | | |
| | L Giustino | 2 | 4 | | | | | | WC | G Sakharov | 6 | 6 | | | | | | |
| | G Gigounon | 6 | 6 | | | G Gigounon | 2 | 4 | | | | | | | | | | |
| WC | G Sakharov | 6 | 7$^7$ | | WC | G Sakharov | 6 | 6 | | | | | | | | | | |
| 4 | L Vanni | 4 | 6$^5$ | | | | | | | | | | | WC | G Sakharov | 6 | 5 | 4 |
| 6 | I Sijsling | 6 | 6 | | | | | | | | | | | 6 | I Sijsling | 3 | 7 | 6 |
| | Y Mertens | 3 | 2 | | 6 | I Sijsling | 6 | 6 | | | | | | | | | | |
| Alt | J Eysseric | 5 | 6$^2$ | | | A Michon | 0 | 3 | | | | | | | | | | |
| | A Michon | 7 | 7$^7$ | | | | | | 6 | I Sijsling | 6 | 6$^2$ | 6 | | | | | |
| | D Guez | 6$^3$ | 6 | 6 | | | | | 2 | D Evans | 4 | 7$^7$ | 4 | | | | | |
| Q | E Corrie | 7$^7$ | 2 | 4 | | D Guez | 3 | 1 | | | | | | | | | | |
| | S Caruso | 6$^4$ | 2 | | 2 | D Evans | 6 | 6 | | | | | | | | | | |
| 2 | D Evans | 7$^7$ | 6 | | | | | | | | | | | | | | | |