# 2010 Italian Open – Women's singles

María José Martínez Sánchez defeated Jelena Janković in the final, 7–6$^{(7–5)}$, 7–5 to win the women's singles tennis title at the 2010 Italian Open. Martínez Sánchez was unseeded in the main draw.
Dinara Safina was the defending champion, but lost in the second round to Alexandra Dulgheru.
Top seed and world No. 1 Serena Williams made it to the semifinals, but was edged by Janković after failing to convert a match point. Unseeded and former world No. 1 Ana Ivanovic also made a surprise run into the semifinals by beating two top 10 players and a top 15 player, but failed to defeat Martínez Sánchez.

## Seeds

The top eight seeds receive a bye into the second round.
* Serena Williams (semifinals)
* Caroline Wozniacki (third round)
* Dinara Safina (second round)
* Venus Williams (quarterfinals)
* Svetlana Kuznetsova (second round)
* Elena Dementieva (third round)
* Jelena Janković (final)
* Agnieszka Radwańska (third round)
* Victoria Azarenka (second round)
* Samantha Stosur (withdrew due to fatigue)
* Yanina Wickmayer (third round)
* Flavia Pennetta (second round)
* Francesca Schiavone (second round)
* Nadia Petrova (quarterfinals)
* Vera Zvonareva (first round)
* Shahar Pe'er (third round)

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final | Final |
| 1/WC | Serena Williams | 6 | 6 | | | | | | | | | |
| | Maria Kirilenko | 1 | 4 | | | | | | | | | |
| | Maria Kirilenko | 1 | 4 | 1/WC | Serena Williams | 6 | 3 | 6$^5$ | | | | |
| | | | | 7 | Jelena Janković | 4 | 6 | 7$^7$ | | | | |
| 4 | Venus Williams | 0 | 1 | 7 | Jelena Janković | 4 | 6 | 7$^7$ | | | | |
| 7 | Jelena Janković | 6 | 6 | | | | | | | | | |
| 7 | Jelena Janković | 6 | 6 | | | | | | 7 | Jelena Janković | 6$^5$ | 5 |
| | | | | | | | | | | María José Martínez Sánchez | 7$^7$ | 7 |
| | Ana Ivanovic | 6 | 7 | | | | | | | | | | María José Martínez Sánchez | 7$^7$ | 7 |
| 14 | Nadia Petrova | 2 | 5 | | | | | | | | | |
| 14 | Nadia Petrova | 2 | 5 | | Ana Ivanovic | 4 | 2 | | | | | |
| | | | | | María José Martínez Sánchez | 6 | 6 | | | | | |
| | Lucie Šafářová | 6$^6$ | 4 | | María José Martínez Sánchez | 6 | 6 | | | | | |
| | María José Martínez Sánchez | 7$^8$ | 6 | | | | | | | | | |

### Top half
#### Section 1

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Third round | Third round | Third round | Third round | Third round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals |
| | | | | | 1/WC | S Williams | 7$^7$ | 6 | | | | | | | | | | |
| | S Záhlavová | 0 | 4 | | | T Bacsinszky | 6$^2$ | 1 | | | | | | | | | | |
| | T Bacsinszky | 6 | 6 | | | | | | | 1/WC | S Williams | 6 | 3 | 6 | | | | |
| | A Petkovic | 6 | 6 | | | | | | | | A Petkovic | 2 | 6 | 0 | | | | |
| | V Dushevina | 3 | 0 | | | A Petkovic | 6 | 6 | | | | | | | | | | |
| | P Kvitová | 6 | 6 | | | P Kvitová | 3 | 4 | | | | | | | | | | |
| 15 | V Zvonareva | 4 | 0 | | | | | | | | | | | | 1/WC | S Williams | 6 | 6 |
| LL | P Parmentier | 1 | 6 | 5 | | | | | | | | | | | | M Kirilenko | 1 | 4 |
| | D Cibulková | 6 | 3 | 7 | | D Cibulková | 6 | 6 | | | | | | | | | | |
| | A Brianti | 6 | 7$^7$ | | | A Brianti | 3 | 4 | | | | | | | | | | |
| | A Pavlyuchenkova | 4 | 6$^5$ | | | | | | | | D Cibulková | 6 | 1 | 1 | | | | |
| | M Kirilenko | 6 | 6 | | | | | | | | M Kirilenko | 4 | 6 | 6 | | | | |
| WC | R Oprandi | 1 | 3 | | | M Kirilenko | 6 | 3 | 6 | | | | | | | | | |
| | | | | | 5 | S Kuznetsova | 2 | 6 | 4 | | | | | | | | | |

#### Section 2

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Third round | Third round | Third round | Third round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals |
| | | | | | 4 | V Williams | 6 | 6 | | | | | | | | | |
| | G Dulko | 7$^7$ | 2 | 6$^5$ | | P Schnyder | 2 | 2 | | | | | | | | | |
| | P Schnyder | 6$^5$ | 6 | 7$^7$ | | | | | | 4 | V Williams | 6 | 6 | | | | |
| | P Hercog | 6 | 6 | | | | | | | 16 | S Pe'er | 3 | 4 | | | | |
| Q | G Arn | 3 | 3 | | | P Hercog | 6 | 5 | 3 | | | | | | | | |
| WC | C Dentoni | 2 | 1 | | 16 | S Pe'er | 2 | 7 | 6 | | | | | | | | |
| 16 | S Pe'er | 6 | 6 | | | | | | | | | | | 4 | V Williams | 0 | 1 |
| 11 | Y Wickmayer | 6 | 1 | 6 | | | | | | | | | | 7 | J Janković | 6 | 6 |
| Q | K Šprem | 3 | 6 | 4 | 11 | Y Wickmayer | 6 | 6$^2$ | 7 | | | | | | | | |
| Q | A Morita | 4 | 2 | | | A Rezaï | 3 | 7$^7$ | 5 | | | | | | | | |
| | A Rezaï | 6 | 6 | | | | | | | 11 | Y Wickmayer | 2 | 0 | | | | |
| Q | B Mattek-Sands | 6 | 6 | | | | | | | 7 | J Janković | 6 | 6 | | | | |
| | M Oudin | 1 | 3 | | Q | B Mattek-Sands | 3 | 6 | 1 | | | | | | | | |
| | | | | | 7 | J Janković | 6 | 3 | 6 | | | | | | | | |

### Bottom half
#### Section 3

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Third round | Third round | Third round | Third round | Third round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals |
| | | | | | 6 | E Dementieva | 6 | 7 | | | | | | | | | | |
| | Y Shvedova | 6 | 6 | | | Y Shvedova | 4 | 5 | | | | | | | | | | |
| Q | B Jovanovski | 2 | 2 | | | | | | | 6 | E Dementieva | 1 | 6$^5$ | | | | | |
| | A Ivanovic | 6 | 6 | | | | | | | | A Ivanovic | 6 | 7$^7$ | | | | | |
| | E Vesnina | 1 | 3 | | | A Ivanovic | 6 | 6 | | | | | | | | | | |
| Q | S Karatantcheva | 1 | 4 | | 9 | V Azarenka | 4 | 4 | | | | | | | | | | |
| 9 | V Azarenka | 6 | 6 | | | | | | | | | | | | | A Ivanovic | 6 | 7 |
| 14 | N Petrova | 6 | 6 | | | | | | | | | | | | 14 | N Petrova | 2 | 5 |
| | T Garbin | 3 | 2 | | 14 | N Petrova | 6 | 6 | | | | | | | | | | |
| Q | V Lepchenko | 7$^7$ | 5 | 3 | PR | K Srebotnik | 4 | 4 | | | | | | | | | | |
| PR | K Srebotnik | 6$^2$ | 7 | 6 | | | | | | 14 | N Petrova | 6 | 3 | 6 | | | | |
| | S Errani | 6 | 1 | 4 | | | | | | | A Dulgheru | 0 | 6 | 2 | | | | |
| | A Dulgheru | 2 | 6 | 6 | | A Dulgheru | 6 | 6$^5$ | 6 | | | | | | | | | |
| | | | | | 3 | D Safina | 4 | 7$^7$ | 1 | | | | | | | | | |

#### Section 4

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Third round | Third round | Third round | Third round | Third round | Quarterfinals | Quarterfinals | Quarterfinals |
| | | | | | 8 | A Radwańska | 6 | 6 | | | | | | | | |
| | R Vinci | 7$^8$ | 7$^7$ | | | R Vinci | 1 | 0 | | | | | | | | |
| | A Kleybanova | 6$^6$ | 6$^5$ | | | | | | 8 | A Radwańska | 6 | 3 | 6$^1$ | | | |
| | L Šafářová | 6 | 6$^9$ | 6 | | | | | | L Šafářová | 1 | 6 | 7$^7$ | | | |
| | O Govortsova | 2 | 7$^{11}$ | 3 | | L Šafářová | 6 | 6 | | | | | | | | |
| Q | A Amanmuradova | 2 | 3 | | 12 | F Pennetta | 1 | 2 | | | | | | | | |
| 12 | F Pennetta | 6 | 6 | | | | | | | | | | | L Šafářová | 6$^6$ | 4 |
| 13 | F Schiavone | 3 | 6 | 6 | | | | | | | | | | MJ Martínez Sánchez | 7$^8$ | 6 |
| | D Hantuchová | 6 | 2 | 2 | 13 | F Schiavone | 2 | 2 | | | | | | | | |
| | A Kudryavtseva | 7 | 4 | 3 | | MJ Martínez Sánchez | 6 | 6 | | | | | | | | |
| | MJ Martínez Sánchez | 5 | 6 | 6 | | | | | | MJ Martínez Sánchez | 6 | 6 | | | | |
| WC | ME Camerin | 6 | 4 | 6 | | | | | 2 | C Wozniacki | 4 | 2 | | | | |
| | J Zheng | 4 | 6 | 4 | WC | ME Camerin | 1 | 0 | | | | | | | | |
| | | | | | 2 | C Wozniacki | 6 | 6 | | | | | | | | |