# 2010 Serbia Open – Singles

Sam Querrey defeated John Isner in the final, 3–6, 7–6$^{(7–4)}$, 6–4 to win the singles tennis title at the 2010 Serbia Open.
Novak Djokovic was the defending champion, but retired in the quarterfinals against Filip Krajinović.

## Seeds

The first four seeds gets a first-round bye.
* Novak Djokovic (quarterfinals, retired due to breathing problems)
* John Isner (final)
* Sam Querrey (champion)
* Stanislas Wawrinka (semifinals)
* Ivo Karlović (second round)
* Viktor Troicki (quarterfinals)
* Janko Tipsarević (withdrew, illness)
* Andreas Seppi (second round)

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final | Final | Final |
| WC | Filip Krajinović | 1 | 2 | | | | | |
| 3 | Sam Querrey | 6 | 6 | | | | | |
| 3 | Sam Querrey | 6 | 6 | 3 | Sam Querrey | 3 | 7 | 6 |
| | | | | 2 | John Isner | 6 | 6$^4$ | 4 |
| 4 | Stanislas Wawrinka | 5 | 5 | 2 | John Isner | 6 | 6$^4$ | 4 |
| 2 | John Isner | 7 | 7 | | | | | |

### Top half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| | | | | | 1 | N Djokovic | 6 | 6 | | | | | | | | | | |
| | F Fognini | 6 | 6 | | | F Fognini | 4 | 4 | | | | | | | | | | |
| Q | F Škugor | 3 | 1 | | | | | | | 1 | N Djokovic | 4 | r | | | | | |
| Q | E Donskoy | 7 | 6$^7$ | 1 | | | | | | WC | F Krajinović | 6 | | | | | | |
| WC | F Krajinović | 5 | 7 | 6 | WC | F Krajinović | 6 | 1 | 7 | | | | | | | | | |
| | H Zeballos | 2 | 6 | 7 | | H Zeballos | 3 | 6 | 6$^5$ | | | | | | | | | |
| LL | P Polansky | 6 | 4 | 6$^2$ | | | | | | | | | | | WC | F Krajinović | 1 | 2 |
| | | | | | | | | | | | | | | | 3 | S Querrey | 6 | 6 |
| | | | | | 3 | S Querrey | 6 | 6 | | | | | | | | | | |
| | E Korolev | 6 | 6 | | | E Korolev | 3 | 4 | | | | | | | | | | |
| | M Russell | 1 | 0 | | | | | | | 3 | S Querrey | 6 | 2 | 6 | | | | |
| | I Andreev | 6 | 6 | | | | | | | | I Andreev | 3 | 6 | 4 | | | | |
| | B Kavčič | 3 | 2 | | | I Andreev | 6 | 7 | | | | | | | | | | |
| WC | D Lajović | 6$^4$ | 4 | | 5 | I Karlović | 4 | 5 | | | | | | | | | | |
| 5 | I Karlović | 7 | 6 | | | | | | | | | | | | | | | |

### Bottom half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 6 | V Troicki | 6 | 6 | | | | | | | | | | | | | | | |
| | I Navarro | 4 | 0 | | 6 | V Troicki | 6 | 6 | | | | | | | | | | |
| | K Beck | 3 | 3 | | | F Serra | 0 | 1 | | | | | | | | | | |
| | F Serra | 6 | 6 | | | | | | | 6 | V Troicki | 5 | 7 | 6$^6$ | | | | |
| WC | M Djokovic | 7 | 5 | 0 | | | | | | 4 | S Wawrinka | 7 | 6$^3$ | 7 | | | | |
| Q | A di Mauro | 6$^5$ | 7 | 6 | Q | A di Mauro | 1 | 4 | | | | | | | | | | |
| | | | | | 4 | S Wawrinka | 6 | 6 | | | | | | | | | | |
| | | | | | | | | | | | | | | | 4 | S Wawrinka | 5 | 5 |
| 8 | A Seppi | 2 | 6 | 6 | | | | | | | | | | | 2 | J Isner | 7 | 7 |
| | L Mayer | 6 | 1 | 4 | 8 | A Seppi | 6 | 2 | 5 | | | | | | | | | |
| | O Rochus | 0 | 1 | | | R Gasquet | 4 | 6 | 7 | | | | | | | | | |
| | R Gasquet | 6 | 6 | | | | | | | | R Gasquet | 6 | 6$^2$ | 3 | | | | |
| Q | F Cipolla | 3 | 0 | | | | | | | 2 | J Isner | 2 | 7 | 6 | | | | |
| | J Ouanna | 6 | 6 | | | J Ouanna | 2 | 4 | | | | | | | | | | |
| | | | | | 2 | J Isner | 6 | 6 | | | | | | | | | | |