OpenLLM-France/wikimedia huggingface dataset:
# Nadofaragene firadenovec

Nadofaragene firadenovec, sold under the brand name Adstiladrin, is a gene therapy for the treatment of bladder cancer. It is a non-replicating (cannot multiply in human cells) adenoviral vector-based gene therapy.
The most common adverse events including laboratory abnormalities, include increased glucose, instillation site discharge, increased triglycerides, fatigue, bladder spasm, micturition urgency, increased creatinine, hematuria, decreased phosphate, chills, dysuria, and pyrexia.
Nadofaragene firadenovec was approved for medical use in the United States in December 2022.

## Medical uses

Nadofaragene firadenovec is indicated for the treatment of adults with high-risk Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle-invasive bladder cancer (NMIBC) with carcinoma in situ (CIS) with or without papillary tumors.

## History

The safety and effectiveness of nadofaragene firadenovec was evaluated in a multicenter clinical study (Study CS-003 (NCT02773849)) that included 157 participants with high-risk Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle-invasive bladder cancer, 98 of whom had BCG-unresponsive carcinoma in situ with or without papillary tumors and could be evaluated for response. Participants received nadofaragene firadenovec once every three months for up to twelve months, or until unacceptable toxicity to therapy or recurrent high-grade non-muscle-invasive bladder cancer. Overall, 51% of enrolled participants using nadofaragene firadenovec therapy achieved a complete response (the disappearance of all signs of cancer as seen on cystoscopy, biopsied tissue, and urine). The median duration of response was 9.7 months. Forty-six percent of responding participants remained in complete response for at least one year. The major efficacy outcome measures were complete response at any time and duration of response. Complete response was defined as negative cystoscopy with applicable transurethral resection of bladder tumor and biopsies and urine cytology. Random bladder biopsies of five sites were conducted in participants remaining in complete response at twelve months.
The US Food and Drug Administration (FDA) granted the application for nadofaragene firadenovec priority review, breakthrough therapy, fast track, and orphan drug designations. The FDA granted approval of Adstiladrin to Ferring Pharmaceuticals A/S.

## Society and culture
### Names

Nadofaragene firadenovec is the international nonproprietary name (INN).
# Gokalgarh, Rewari

Gokalgarh is a village Near Hanuman Mandir Astal in Rewari block, in the Indian state of Haryana. It is a village at about 10 kilometres (6.2 mi) from Rewari city and is situated on Rewari- Jhajjar District Road.

## Railway Station

It has a railway station from Rewari, It is first on Rewari-Rohtak line. Its railway station is 13.6 kilometres (8.5 mi) away from Rewari Bus stand.

## Gokalgarh Fort

In Mughal times, although Rewari was the headquarters of a Sarkar or district of the empire, its Ahir Rajás appear to have enjoyed a large measure of independence, paying tribute at a fixed rate to the emperors, and coining their own money. Rao Gujarmal built the fort of Gokalgarh, two miles from Rewari (Ahirwal), some of the bastions of which still remain as indications of the former strength and size of the place, and which gave its name to the coinage known as Gokal sicca that was still in circulation at Farrukhnagar in the time of the Mutiny, passing for 13 or 14 annas of our money. Rao Bal Kishan who fought against Nadirshah at Karnal in year 1739, single handedly fought against 75000 well equipped soldiers.

## Demographics of 2011

As of 2011 India census, Gokalgarh is a large village with total 12750 families residing. The Gokalgarh village has population of 6331 of which 3341 are males while 2990 are females as per Population Census 2011. In Gokalgarh village population of children with age 0-6 is 762 which makes up 12.04% of total population of village. Average Sex Ratio of Gokalgarh village is 895 which is higher than Haryana state average of 879. Child Sex Ratio for the Gokalgarh as per census is 736, lower than Haryana average of 834.
Gokalgarh village has higher literacy rate compared to Haryana. In 2011, literacy rate of Gokalgarh village was 81.88% compared to 75.55% of Haryana. In Gokalgarh Male literacy stands at 93.49% while female literacy rate was 69.25%.
As per constitution of India and Panchyati Raaj Act, Gokalgarh village is administrated by Sarpanch (Head of Village) who is elected representative of village.

## Adjacent villages

* Mastapur
* Guraora
* Kulana
* Lisana
* Bikaner
# Aeolostoma

Aeolostoma is a genus of moths belonging to the subfamily Tortricinae of the family Tortricidae.

## Species

* Aeolostoma melanostoecha Diakonoff, 1953
* Aeolostoma orophila Diakonoff, 1953
* Aeolostoma scutiferana (Meyrick, 1881)
# Walls of Jericho

The Walls of Jericho usually refer to the destruction of the walls of Jericho in the biblical story of the Battle of Jericho.
Walls of Jericho may also refer to:
* Wall of Jericho (Neolithic), a prehistoric wall around the city of Jericho
* Wrestler Chris Jericho’s signature submission, The Boston Crab, also known as the Walls of Jericho.

## Film and television

* The Walls of Jericho (1914 film), an American silent drama film
* The Walls of Jericho (1948 film), an American drama film
* "The Walls of Jericho", an episode of The Time Tunnel
* "Walls of Jericho" (Jericho episode), 2006

## Music

* Walls of Jericho (band), an American metalcore band
* "Walls of Jericho", a 1982 song by post-punk band Virgin Prunes
* Walls of Jericho (album), a 1985 album by Helloween
* "Walls of Jericho", a 1990 song by Cabaret Voltaire

## Places

* The Walls of Jericho (canyon), a nature reserve in North Alabama and Middle Tennessee
* Wall of Jericho, a mountain in Banff National Park, Alberta, Canada

## Other uses

* The Walls of Jericho, a 1928 novel by Rudolph Fisher
* Walls of Jericho, a finishing move of American-Canadian professional wrestler Chris Jericho
# Toribio Ticona Porco

Toribio Ticona Porco (Spanish pronunciation:; born 25 April 1937) is a Bolivian prelate of the Catholic Church. He was Prelate of the Territorial Prelature of Corocoro from 1992 to 2012 after serving as Auxiliary Bishop of Potosí from 1986 to 1992. Pope Francis made him a cardinal on 28 June 2018.
Of Quechuan origin, he was the first Latin American cardinal from one of the continent's indigenous ethnic groups.

## Biography

Toribio Ticona Porco was born in Atocha in the Potosi Department of Bolivia, on 25 April 1937. He was raised by his mother and never knew his father. He worked shining shoes and selling newspaper, was a bricklayer's assistant and an auto mechanic and worked in a brewery. He became a Catholic under the influence of Belgian missionaries. He first worked for the missionaries as a bell ringer and secretary in Atocha. He began his preparation for the priesthood in 1962 at a center for late vocations in Chile, but returned to Bolivia after only two months. At the Belgians' insistence he studied philosophy and theology for four years at the seminary in Sucre. He was ordained a priest of the Diocese of Potosí on 29 January 1967. He did further studies at the Pastoral Institute of CELAM and at the Center Lumen Vitae in Brussels. While a priest in Chacarilla, a mining town of 2,000 people, he was mayor for 14 years.
On 5 April 1986, Pope John Paul II appointed him titular bishop of Timici and auxiliary bishop of Potosí, and he was consecrated a bishop on 31 May 1986 by Archbishop Santos Abril y Castelló, the apostolic nuncio to Bolivia. As an auxiliary bishop, he worked in the mining region of northern Potosí, based in the town of Uncía in Chayanta Province.
On 4 June 1992, John Paul appointed him Prelate of the Territorial Prelature of Corocoro.
Pope Benedict XVI accepted his resignation on 29 June 2012.
On 20 May 2018 Pope Francis announced he would make Ticona a cardinal on 28 June. Ticona learned of the surprise appointment while visiting his mother's grave near Quillacollo. At the 28 June consistory, he was assigned the titular church of Santi Gioacchino ed Anna al Tuscolano. Bolivian President Evo Morales attended the ceremony and said he witnessed the creation of "our first indigenous cardinal and worker" with "profound happiness and joy".
# Alewife (multiprocessor)

Alewife was a cache coherent multiprocessor developed in the early 1990s by a group led by Anant Agarwal at the Massachusetts Institute of Technology. It was based on a network of up to 512 processing nodes, each of which used the Sparcle computer architecture, which was formed by modifying a Sun Microsystems SPARC CPU to include the APRIL techniques for fast context switches.
The Alewife project was one of two predecessors cited by the creators of the popular Beowulf cluster multiprocessor.
# Lili Zhou

Lili Zhou (born December 2, 1989) is a female badminton player from the United States of America.
From 2004 to 2006 she won three times the women's singles at the Boston Badminton Open. She played at the 2005 World Badminton Championships but lost in the first round to Eriko Hirose of Japan.

## Major Achievements

* 1993 Eleventh Sports Meeting of Guangzhou Singles 1st place
* 1993 Eleventh Sports Meeting of Guangzhou Doubles .2nd place
* 1994 Guangxi Jr. Badminton Championships Singles 1st place
* 1994 China National Contest of Excellent Players
* 1997 China National Jr. Badminton Championships Doubles 4thplace
* 1998 China National Badminton Winter Competition “Victory Cup” 1st place
* 1999 China National Badminton Championships of University 1st
* 2000 US Classic Doubles 1st place
* 2001 US Classic Doubles 1st place
* 2003 Bay Area Open 1st place
* 2004 Boston Open singles/ Mixed doubles 1st
* 2004 US Adult National Singles/ doubles 1st place
* 2004 US Open Singles 2nd place
* 2005 Honolulu Open Singles/ Doubles 1st place
* 2005 Boston Open Singles/ Doubles 1st place
* 2005 UBC Open Singles/Mixed 1st place
* 2005 YONEX International Championship 2005 1st place
* 2006 Boston open singles 1st place
* 2006 GGBC Open Singles 1st place
* 2007 Won the USA National Team Trials
* 2007 GGBC Open Singles 1st place
* 2008 USA Team Trial Singles 1st place
* 2008 U.S. Open Singles 1st Place
# Samuel San José

Samuel San José Fernández (born 1 March 1984), known simply as Samuel or Samu for short, is a Spanish former professional footballer who played as a central defender, currently manager of UM Escobedo.

## Club career

Born in Santander, Cantabria, Samu was a product of his hometown club Racing de Santander's youth system. He first appeared for its main squad on 11 September 2005, in a 0–1 home loss against Cádiz CF. He finished the season with seven appearances (all but one were complete matches) and four yellow cards, as the Cantabria side finished 17th in La Liga and narrowly avoided relegation.
After having served a season-long loan stint with Sporting de Gijón in the Segunda División, Samuel returned to Racing but, midway through the 2007–08 campaign, would be loaned again, alongside teammate Christian Fernández, to second-tier strugglers UD Las Palmas. Both would be instrumental in helping the Canarians to retain their league status.
Subsequently, Christian returned to Santander but Samu stayed, signing for three years with the option for a further one. He appeared in an average of 23 games the following three seasons, with his team always managing to stay afloat in division two.
Samuel then alternated between the second division and the Segunda División B, representing SD Ponferradina and Racing Santander and achieving promotion with the former in 2012. He spent 2015–16 in the Mexican Ascenso MX, with Atlético San Luis.
After returning to his home country, Samu saw out his career at age 39, playing lower-league and amateur football with UD Llagostera, SD Formentera and UM Escobedo.

## Coaching career

Samu was named manager of his last club immediately after retiring. On 19 May 2024, having achieved promotion to Segunda Federación as group winners, he renewed his contract for a further year.

## Managerial statistics

    As of match played 23 February 2025
Managerial record by team and tenure :
| Team | Nat | From | To | Record | Record | Record | Record | Record | Record | Record | Record | Ref |
| Team | Nat | From | To | G | W | D | L | GF | GA | GD | Win % | Ref |
| Escobedo | | 16 June 2023 | Present | 62 | 29 | 16 | 17 | 77 | 64 | +13 | 046.77 | |
| Career total | Career total | Career total | Career total | 62 | 29 | 16 | 17 | 77 | 64 | +13 | 046.77 | — |
# 1575 in Norway

"none" is preferred when the title is sufficiently descriptive
Events in the year 1575 in Norway.

## Incumbents

* Monarch: Frederick II.

## Events

* Anti-Catholicism in Norway: Ingeborg Kjeldsdatter from Skiptvet was flogged. Her crime was that she had practiced Catholic Marian devotion.
* 12 December – The Danzig rebellion began. The city of Danzig rebels against Poland–Lithuania, Denmark–Norway joins the side of the rebels.

## Deaths

* 9 April – Absalon Pederssøn Beyer, clergyman, writer, historian (born c. 1528).
* 29 July – Jon Simonssøn, city manager, lawspeaker, humanist (born 1512).
# Philip Yorke, 3rd Earl of Hardwicke

Philip Yorke, 3rd Earl of Hardwicke (31 May 1757 – 18 November 1834), known as Philip Yorke until 1790, was a British politician.

## Background and education

Born in Cambridge, England, he was the eldest son of Charles Yorke, Lord Chancellor, by his first wife, Catherine Freman. He was educated at Harrow and Queens' College, Cambridge.
On 31 January 1788 his uncle Philip Yorke, 2nd Earl of Hardwicke, as Lord Lieutenant of Cambridgeshire, appointed him as Colonel of the Cambridgeshire Militia, a command which he held for many years, even after he had become Lord Lieutenant himself.
In 1790 he succeeded his uncle to his earldom and estates, including Wimpole Hall.

## Political career

Hardwicke was Member of Parliament for Cambridgeshire from 1780 to 1790, following the Whig traditions of his family, but after his succession to the earldom in 1790 he supported William Pitt The Younger, and took office in 1801 as Lord Lieutenant of Ireland (1801–1806), where he supported Catholic emancipation. He was sworn of the Privy Council in 1801, created a Knight of the Garter in 1803, and was a fellow of the Royal Society.

## Family

Lord Hardwicke married Lady Elizabeth, daughter of James Lindsay, 5th Earl of Balcarres, in 1782. They had four sons and four daughters.
* Philip Yorke, Viscount Royston (7 May 1784 – 7 April 1808), Member of Parliament for Reigate but was lost at sea off Lübeck (having died without issue);
* Lady Anne Yorke (13 April 1783 – 17 July 1870); married John Savile, 3rd Earl of Mexborough, and had issue.
* Lady Catherine Freeman Yorke (14 April 1786 – 8 July 1863); married Du Pré Alexander, 2nd Earl of Caledon, and had issue.
* Charles Yorke (23 August 1787 – 28 December 1791)
* Lady Elizabeth Margaret Yorke (1789 – 23 June 1867); married Charles Stuart, 1st Baron Stuart de Rothesay, and had issue.
* Lady Caroline Harriet Yorke (15 October 1794 – 27 May 1873); married John Somers-Cocks, 2nd Earl Somers, and had issue.
* Charles James Yorke, Viscount Royston (14 July 1797 – 30 April 1810); died at Wimpole of scarlet fever.
* Hon. Joseph John Yorke (12 August 1800 – 23 March 1801), died in infancy
Lord Hardwicke died on 18 November 1834, aged 77, and was buried St Andrew's Church in Wimpole, Cambridgeshire, in a tomb by Richard Westmacott the Younger. As he had no surviving male issue, he was succeeded in the earldom by his nephew Charles. Lady Hardwicke died on 26 May 1858, aged 94.
# Israel Gutiérrez

José Israel Gutiérrez Zermeño (born 15 January 1993) is a Mexican basketball player for Dorados de Chihuahua and the Mexico national team, where he participated at the 2014 FIBA Basketball World Cup. He played college basketball for the Borregos ITESM Hidalgo.

## National team career

Gutiérrez represented the Mexico national team at the 2014 FIBA World Cup and 2016 Centrobasket. He then won a bronze medal at the 2017 FIBA AmeriCup held in Argentina. He later captained Mexico at the 2019 Pan American Games.

## Personal life

Both of Gutiérrez's parents are from Jalisco: his mother from San Julián and his father from San Miguel el Alto.
# Macrouridae

Macrouridae is a family of deep sea fish, a diverse and ecologically important group, which are part of the order of cod-like fish, the Gadiformes. The species in the Macrouridae are characterised by their large heads which normally have a single barbel on the chin, projecting snouts, and slender bodies that taper to whip-like tails, without an obvious caudal fin but what there is of the caudal fin is often confluent with the posterior dorsal and anal fins. There are normally two dorsal fins, the anterior dorsal fin is quite high, the posterior quite low but is longer and takes up a greater proportion of the fish's back. Species in the subfamily Macrouroidinae have a single dorsal fin. The long anal fin is almost as long as the posterior dorsal fin, and sometimes it is longer. The pelvic fin is inserted in the vicinity of the thorax and normally has 5–17 fin rays but these are absent in Macrouroides. The body is covered in small scales and if they have a photophore, it is usually on the midline of the abdomen just in front of the anus. The bioluminescence of these fish is produced by symbiotic bioluminescent bacteria. The structure of the skull has been used to show their placing in the Gadiformes, but they differ from the typical cods in that they possess one stout spine in the anterior dorsal fin.
The species in this family are mainly benthopelagic, they are found at depths of 200–2000 m, they occur on the sea bed and have a wide distribution from the Arctic to the Antarctic. The species in the Macrouridae normally live near the sea bed on the continental slope, however, some species are bathypelagic or mesopelagic, other species occur on the outer continental shelf. Their bodies are loose in texture rather than firm and they are weak swimmers. Some species are of commercial importance to fisheries.

## Subfamilies

There are four subfamilies within the Macrouridae:
* Bathygadinae: contains 2 genera and 26 species
* Macrourinae: contains 28 genera and 370 species
* Macrouroidinae: contains 2 monotypic genera
* Trachyrincinae contains 2 genera and 7 species
The earliest known genus is Bobbitichthys Schwarzhans, Milàn & Carnevale, 2021, a stem-macrourid from the middle Paleocene of Denmark. A well-preserved skull of an indeterminate macrourid is known from the Eocene-aged La Meseta Formation of Antarctica. The extinct genus Bolbocara Jordan, 1927 is known from an articulated fossil skeleton from the Late Miocene of California, while Razelaina Carnevale, 2007 is known from the Late Miocene of Algeria.
# Alone (Big Country song)

"Alone" is a song by Scottish rock band Big Country, released in March 1993 as the lead single from their sixth studio album The Buffalo Skinners. It was written by Stuart Adamson and produced by Big Country. "Alone" reached number 24 in the UK Singles Chart and remained in the top 100 for three weeks.

## Background

The release of "Alone" as the album's first single was a band decision. Adamson told the fanzine Country Club in 1993, "I always wanted that as the first single. I wanted the first single to be a rock track and the record company were happy to go along with that."

## Music video

The song's music video was directed by Roger Pomphrey and features Martin Chambers on drums.

## Critical reception

Upon its release as a single, Larry Flick of Billboard commented, "Familiar traces of a Scottish accent in Adamson's strong, melodic vocal notwithstanding, the band effectively reintroduces itself on this single - and radio should welcome it back. Alternating passages of light and heavy pop are mixed with a crashing beat and blazing lead-guitar lines." In a review of The Buffalo Skinners, Neil McKay of Sunday Life described the song as "rousing and tuneful as in [Big Country's] early heyday". Dan Hyatt of the Albuquerque Journal noted: "The first song, "Alone," has all the earmarks of an anthem for the '90s, kind of a "what's my place in the world, and why" song."
Kevin Belvins of The Leader-Post noted: "The album's refreshing tone is set immediately with the frantic opening cut "Alone"." In a review of one of the band's 1993 concerts, Diana Aitchison of the St. Louis Post-Dispatch commented: "One song to watch for on the charts is "Alone," which opens with a moody staccato guitar and gels with the band's signature reeling bagpipe sound." Johnny Loftus of AllMusic described the song as "a template for the entire album", with "churning guitar and bass", an "impossibly triumphant chorus" and "rangy solo".

## Track listing

Cassette single
* "Alone" – 5:08
* "Chance" (Live) – 7:28
CD single and UK 12-inch single
* "Alone" – 5:08
* "Never Take Your Place" – 4:01
* "Rockin' in the Free World" – 6:47
CD single (UK #1)
* "Alone" – 5:08
* "Rockin' in the Free World" – 6:47
* "Eastworld" – 4:39
* "Chance" (Live) – 7:28
CD single (UK #2)
* "Alone" – 5:08
* "Never Take Your Place" – 4:01
* "Winter Sky" (Live) – 4:36
* "Look Away" (Live) – 4:42
CD single (US promo)
* "Alone" (Album Version) – 5:08
* "Alone (Edit) – 4:06

## Personnel

Big Country
* Stuart Adamson – vocals, guitar
* Bruce Watson – guitar
* Tony Butler – bass, backing vocals
Additional musicians
* Simon Phillips – drums
Production
* Big Country – producers of "Alone", producers and mixing on "Never Take Your Place", "Rockin' in the Free World" and "Eastworld"
* Mike Fraser – mixing on "Alone"
* Chris Sheldon – recording on "Alone" and "Rockin' in the Free World"
* Stuart Hamilton – recording on "Never Take Your Place" and "Eastworld"
* Pete Dauncey – producer of "Chance", "Winter Sky" and "Look Away" (Live)
* Gareth Watson – engineer on "Chance", "Winter Sky" and "Look Away" (Live)

## Charts

| Chart (1993) | Peak position |
| UK Singles Chart | 24 |
# 2018–19 Feyenoord Basketball season

The 2018–19 Feyenoord Basketball season was the 65th season in the existence of the club. The club will play in the Dutch Basketball League (DBL) and NBB Cup.
It was the first season as Feyenoord Basketball and the first season under head coach Richard den Os. On 2 March 2019, Den Os resigned as head coach, Jan Stalman replaced him as interim.

## Players
### Squad information

Note: Flags indicate national team eligibility at FIBA-sanctioned events. Players may hold other non-FIBA nationalities not displayed.

## Transactions
### In

| No. | Pos. | Name | Age | Moving from | Moving from | Type | Ends | Date |
| 7 | PG | Emanuele Montaguti | 24 | Free agent | Free agent | Free | Undisclosed | 7 August 2018 |
| 11 | C | Jeroen van der List | 28 | Aris Leeuwarden | | Free | Undisclosed | 7 August 2018 |
| 4 | F | Justin Gordon | 24 | Amal Essaouira | | Free | Undisclosed | 7 August 2018 |
| 12 | PG | La'Shard Anderson | 29 | Near East University | | Free | Undisclosed | 7 August 2018 |
| 3 | G | Sam van Dijk | 21 | BAL | | Free | Undisclosed | 7 August 2018 |
| 13 | F | Rens van Ravensteijn | 23 | Apollo Amsterdam | | Free | Undisclosed | 7 August 2018 |

### Out

| No. | Pos. | Name | Age | Moving to | Moving to | Type | Date |
| 5 | PG | Ordane Kanda-Kanyndia | 21 | Kangoeroes Mechelen | | End of contract | 1 July 2019 |
| 8 | SF | Maik Bouwer | 20 | Free agent | Free agent | End of contract | 1 July 2019 |
| 12 | C | Marcel Boyd | 26 | Free agent | Free agent | End of contract | 1 July 2019 |
| 2 | PG | Joey Puddister | 26 | Sudbury Five | | End of contract | 1 July 2019 |
| 7 | F | Michael Madanly | 37 | Free agent | Free agent | End of contract | 1 July 2019 |
| 44 | C | Ruben Blaakman | 19 | Free agent | Free agent | End of contract | 1 July 2019 |
| 3 | SF | Jason Rijaard | 20 | Free agent | Free agent | End of contract | 1 July 2019 |

## Dutch Basketball League
### Playoffs

Win  Loss