# Interstate 70 in Missouri

Interstate 70 (I-70) in the US state of Missouri is generally parallel to the Missouri River. This section of the transcontinental interstate begins at the Kansas state line on the Lewis and Clark Viaduct, running concurrently with U.S. Route 24 (US 24), US 40 and US 169, and the east end is on the Stan Musial Veterans Memorial Bridge in St. Louis.

## Route description

Crossing into Missouri on the Lewis and Clark Viaduct, I-70 immediately encounters the Downtown Loop, also called the Alphabet Loop, a small but complex loop of freeways with all of its exits having the number 2 and a letter suffix that uses the entire alphabet (except I and O). I-70 runs concurrently with I-35 once it enters into the Loop. Both Interstates maintain the concurrency until they approach the northeastern corner of the loop. Back at the northwest corner, US 169 splits off to the north, leaving four routes concurrent with each other. There is a large interchange with Route 9 in the loop's northeastern corner. At that corner, I-29 ends, and US 71 joins.
Once it leaves I-35, I-70 turns south, with interchanges to more roads. At the southeastern corner, I-70, US 40, US 24, and US 71 all exit the loop. I-70, US 40, and US 24 split off to the east, and US 71 continues south. I-670 ends at the alignment. Not long after they usurp that alignment, I-70/US 40/US 24 turn southeast. US 40 departs from I-70 at exit 7A. I-70 and US 24 then interchanges with I-435, the beltway around the Kansas City metropolitan area. US 24 departs from I-70 exit 8B and heads north following I-435.
While passing through Kansas City, I-70 is known as the George Brett Super Highway, named after George Brett, the Kansas City Royals’ all-time hits, home runs and runs batted in (RBI) leader, former third baseman and first baseman, and National Baseball Hall of Fame inductee. The Truman Sports Complex, which is named after Harry Truman, houses the Royals' and Kansas City Chiefs' stadiums and is located adjacent to the I-70/I-435 interchange.
East of I-435, I-70 continues east through Independence, the Kansas City Metro Area's largest suburb by both population and area on the Missouri side, passing a busy cloverleaf interchange at I-470. The highway then continues with six lanes to the rapidly growing suburb of Blue Springs, where the roadway narrows to four lanes (two each direction) at Route 7. I-70 remains at this width until just west of the intersection with I-64/US 40/US 61 in Wentzville, over 170 miles (270 km) away.
East of Blue Springs, I-70 takes on a rural highway as it leaves Jackson County. The highway remains this way for the next 100 miles (160 km), going through gently rolling terrain while it meets US 65 at a cloverleaf interchange and finally crossing the Missouri River at Rocheport just west of where it reaches the midsized college town of Columbia in the center of the state. Through Columbia, the highway is lined with restaurants and hotels and can get congested during University of Missouri sporting events. The highway leaves Columbia after an exit with St. Charles Road on the east end of town. East of Columbia, I-70 has an interchange with US 54 at Kingdom City, Route 19 at New Florence, and Route 47 at Warrenton. Then, it continues through more gently rolling terrain until it reaches Wentzville, where it meets I-64/US 61. Here, US 40 departs from I-70. It then expands to three lanes each direction to St. Louis.
East of Wentzville, I-70 passes through the bedroom community of Lake St. Louis, then the growing towns of O'Fallon and St. Peters, and finally the historic city of St. Charles. It crosses over the Missouri River one last time on the Blanchette Memorial Bridge, which is actually made up of two bridges: the westbound span built in the late 1950s and refurbished in 2013 and the eastbound one completed in the late 1970s.
Traffic volume increases as I-70 enters St. Louis County, requiring more lanes. There are as many as 13 lanes at one point. The section of I-70 from Fifth Street in St. Charles to I-270 is among the busiest section of highway in the state, with annual average daily traffic (AADT) counts approaching 165,000 in 2005.
I-270 draws much of the traffic, so I-70 continues east through Bridgeton with only six lanes. After interchanges with Route 180 (St. Charles Rock Road) and US 67 (Lindbergh Boulevard), it passes on the southern edge of St. Louis Lambert International Airport and through several bedroom communities—including Edmundson, Berkeley, Ferguson, and Jennings—and crossing I-170 in the process.
As it finally enters the city of St. Louis, motorists encounter what are signed as the "Express Lanes", known by the Missouri Department of Transportation (MoDOT) as the "reversible lanes". Two lanes in the middle of the freeway are separated from the eastbound and westbound lanes by Jersey barriers. Due to traffic pattern changes caused by the I-64 reconstruction, the lanes travel eastbound all day. MoDOT regularly monitors traffic patterns of this stretch of I-70 and will adjust the express lane traffic patterns accordingly. These lanes have no entrance or exit ramps, except at the ends. They extend approximately eight miles (13 km) from near Union Boulevard to just north of Downtown St. Louis.
Just before it enters downtown, I-70 turns to the east to cross the Stan Musial Veterans Memorial Bridge, which redirects the highway's traffic away from the congested Poplar Street Bridge two miles (3.2 km) to the south. This two-mile (3.2 km) stretch of former I-70 is now an extension of I-44.

## History

I-70 had been criticized for cutting off downtown from the Mississippi River waterfront particularly at the Gateway Arch. St. Louis constructed a $90-million (equivalent to $127 million in 2023) project to cover the highway (now I-44) by the arch.
This was not the first controversy involving I-70 and the arch. In 1959, builders of the Poplar Street Bridge asked for the National Park Service to give 25 acres (10 ha) of the park for the bridge. The request generated enormous controversy and ultimately 2.5 acres (1.0 ha) was turned over to use for the bridge.
The New Mississippi River Bridge was finished and opened to traffic on Sunday, February 9, 2014. It reroutes and redirects I-70 traffic off the congested Poplar Street Bridge. The bridge was named in honor of St. Louis Cardinals baseball legend Stan Musial.
As of 2021, US 24 follows I-70 east to I-435 north. US 24 that used to follow Independence Avenue will become a business route of US 24.

## Future

I-70 across central Missouri is one of the oldest stretches of Interstate Highway in the system, as some sections date as far back as the late 1950s. As a result, the exits often have short, substandard acceleration and deceleration ramps and the median is relatively narrow. Certain spots of both directions of traffic are separated by no more than a Jersey barrier. Also, a number of overpasses have low clearance, especially railway overpasses. Long-term plans have been identified to expand the highway to between six and eight lanes across the middle of the state. Tolling the Interstate has become a possible alternative, although the public does not support this idea. In May 2023, about $2.8 billion was allocated to widen the interstate throughout the entire state to at least three lanes in each direction. Dubbed as the MODOT’s Improve I-70 program, the project will be broken down in six segments and being construction work in Spring 2024; the work is expected to last about seven years.
A March 2010 study of I-70 from the Kansas state line to the I-470 interchange identified several possible improvements, including expanding the freeway from four to eight lanes, adding high-occupancy vehicle or toll lanes, reconstructing the Truman Road interchange, and improving the curves at Jackson Avenue and Truman Road. Some novel ideas included a new alignment of I-70 as a tunnel from the southeast corner of the downtown loop to 22nd/23rd streets, covering the southern portion of the downtown loop (I-670), or making the downtown loop into a unidirectional freeway around downtown, essentially becoming a large roundabout. In March 2023, Governor Mike Parson announced a proposal to widen I-70 to six lanes (three lanes each way) across the state, which he approved in July 2023.
The Missouri Hyperloop is a proposed high-speed transportation route that would complement and relieve I-70.
MoDOT plans to replace the Rocheport Bridge, which crosses the Missouri River near Rocheport, with two bridges. Originally, one bridge carries four lanes of I-70. Construction of one new span began in 2021 and was completed in July 2023 and the span was imploded 2 months later. A new span was completed in December 2024.

## Exit list

| County | Location | mi | km | Exit | Destinations | Notes |
| Kansas River | Kansas River | 0.000 | 0.000 | | I-70 west / US-24 west / US-40 west / US-169 south / Lewis and Clark Trail – Topeka | Continuation into Kansas |
| Lewis and Clark Viaduct; Kansas–Missouri line |||
| Jackson | Kansas City | 0.886– 1.041 | 1.426– 1.675 | 2A | I-35 south – Wichita | Western end of I-35 / Downtown freeway loop concurrency |
| Jackson | Kansas City | 0.845 | 1.360 | 2B | Beardsley Road | Eastbound exit and westbound entrance |
| Jackson | Kansas City | 1.060 | 1.706 | 2C | US 169 north (Broadway Boulevard) | Eastern end of US 169 concurrency. Access to Charles B. Wheeler Downtown Airport and Downtown |
| Jackson | Kansas City | 1.303 | 2.097 | 2D | Main Street / Delaware Street / Wyandotte Street | Signed as Main Street only eastbound |
| Jackson | Kansas City | 1.651 | 2.657 | 2E | Route 9 north / Oak Street | Westbound access is via exit 2H |
| Jackson | Kansas City | 1.853– 2.028 | 2.982– 3.264 | 2G | I-29 north / I-35 north / US 71 north / Lewis and Clark Trail – St. Joseph, Des Moines | Eastern end of I-35 concurrency; western end of US 71 concurrency; signed as exit 2G–H eastbound; southern terminus of I-29 |
| Jackson | Kansas City | 1.853– 2.028 | 2.982– 3.264 | 2H | To Route 9 north / Admiral Boulevard US 24 Bus. (Independence Avenue) | Westbound exit and eastbound entrance; Substitute exit for Exits 2F and 2E westbound |
| Jackson | Kansas City | 2.273 | 3.658 | 2J | 11th Street to 10th Street VIA Charlotte Street | Eastbound exit and westbound entrance; access to University of Missouri-Kansas City Medical School |
| Jackson | Kansas City | 2.668 | 4.294 | 2K | 12th Street / 11th Street to Charlotte Street / 10th Street / Harrison Street / Troost Avenue | Westbound exit and eastbound entrance |
| Jackson | Kansas City | 2.375– 2.295 | 3.822– 3.693 | 2L | I-670 west to I-35 south – Wichita | I-670 exit 2N |
| Jackson | Kansas City | 2.375– 2.295 | 3.822– 3.693 | 2M | US 71 south – Joplin | Eastern end of US 71 and Downtown freeway loop concurrency; I-670 exit 2N; westbound access is via exit 3A; eastern end of the Bruce Watkins Drive Memorial Parkway; access to UMKC Medical School, and Truman Medical Center-Hospital Hill |
| Jackson | Kansas City | 2.375– 2.295 | 3.822– 3.693 | 2P | 13th Street / Charlotte Street – Downtown | Westbound exit only; access to UMKC Medical School and Truman Medical Center-Hospital Hill |
| Jackson | Kansas City | 2.375– 2.295 | 3.822– 3.693 | | 14th Street / Charlotte Street | Eastbound entrance only |
| Jackson | Kansas City | 2.375– 2.295 | 3.822– 3.693 | 2Q | Truman Road / Locust Street / Oak Street / Grand Boulevard / Walnut Street / Main Street / Baltimore Avenue | Westbound exit and eastbound entrance. Access to Power and Light District and T-Mobile Center. |
| Jackson | Kansas City | 2.944 | 4.738 | 3A | To US 71 south / The Paseo | Westbound exit and entrance and eastbound entrance only. No eastbound exit from I-70 east; no westbound entrance to I-670 west; I-670 exit 3A; access to the American Jazz Museum and the Negro Leagues Baseball Museum |
| Jackson | Kansas City | 3.389 | 5.454 | 3B | Brooklyn Avenue | Eastbound exit and westbound entrance |
| Jackson | Kansas City | 3.644 | 5.864 | 3C | Prospect Avenue | Signed as exit 3B westbound; access to Pioneer College |
| Jackson | Kansas City | 4.135 | 6.655 | 4A | Benton Boulevard / Truman Road | Eastbound exit and westbound entrance |
| Jackson | Kansas City | 4.420 | 7.113 | 4B | 18th Street | Access to American Jazz Museum and Negro Leagues Baseball Museum |
| Jackson | Kansas City | 4.879 | 7.852 | 4C | 23rd Street | |
| Jackson | Kansas City | 5.447 | 8.766 | 5A | 27th Street | Eastbound exit and westbound entrance |
| Jackson | Kansas City | 5.578 | 8.977 | 5B | Myrtle Avenue to 31st Street | Eastbound exit only |
| Jackson | Kansas City | 5.756 | 9.263 | 5C | Jackson Avenue / Myrtle Avenue to 27th Street | Westbound exit and eastbound entrance |
| Jackson | Kansas City | 6.493 | 10.449 | 6 | Van Brunt Boulevard | Access to Veteran Administration Medical Center |
| Jackson | Kansas City | 7.053 | 11.351 | 7A | US 40 east / 31st Street | Eastern end of US 40 overlap |
| Jackson | Kansas City | 7.675 | 12.352 | 7B | Manchester Trafficway | |
| Jackson | Kansas City | 8.078– 9.105 | 13.000– 14.653 | 8 | I-435 south / Blue Ridge Cutoff – Wichita, Truman Sports Complex US 24 east / I-435 north – Des Moines | I-435 exit 63A; signed as exits 8A (south) and 8B (north) |
| Jackson | Kansas City | 9.338 | 15.028 | 9 | Blue Ridge Cutoff –Truman Sports Complex | Westbound exit and eastbound and westbound entrance; eastbound exit 9 via exit 8A |
| Jackson | Kansas City | 10.848 | 17.458 | 10 | Sterling Avenue | Eastbound exit only; westbound entrance to I-70 is via US 40; westbound exit and eastbound entrance via US 40 and I-70 |
| Jackson | Kansas City–Independence line | 11.101– 11.122 | 17.865– 17.899 | 11 | US 40 / Blue Ridge Boulevard | Blue Ridge Boulevard only has eastbound and westbound entrances; except for a ramp to southbound Blue Ridge Boulevard from US 40 eastbound |
| Jackson | Independence | 12.596 | 20.271 | 12 | Noland Road | Access to the Harry S. Truman Presidential Library and Museum and Harry S. Truman National Historic Site |
| Jackson | Independence | 14.093 | 22.680 | 14 | Lee's Summit Road | |
| Jackson | Independence | 15.090– 15.776 | 24.285– 25.389 | 15 | I-470 south / Route 291 – Lee's Summit, Liberty | I-470 exits 16B–C; signed as exits 15A (south/west) and 15B (north); access to Sugar Creek |
| Jackson | Independence | 16.613 | 26.736 | 17 | Little Blue Parkway / 39th Street / Mall Entrance | Access to Centerpoint Medical Center and Independence Event Center |
| Jackson | Blue Springs | 18.563 | 29.874 | 18 | Woods Chapel Road | Access to Lake Tapawingo and Fleming Park |
| Jackson | Blue Springs | 20.392 | 32.818 | 20 | Route 7 – Blue Springs | Access to Lake Lotawana |
| Jackson | Blue Springs | 21.625 | 34.802 | 21 | Adams Dairy Parkway – Blue Springs | |
| Jackson | Grain Valley | 24.412 | 39.287 | 24 | US 40 / Route AA / Route BB – Grain Valley, Buckner | Western end of US 40 concurrency |
| Jackson | Oak Grove | 28.169 | 45.334 | 28 | Route F / Route H – Levasy, Oak Grove | |
| Lafayette | Bates City | 31.431 | 50.583 | 31 | Route D / Route Z – Bates City, Napoleon | |
| Lafayette | Odessa | 36.665 | 59.007 | 37A | Action Road - Outlet Mall | Eastbound exit only; access to Shops at Odessa; attached to exit 37B |
| Lafayette | Odessa | 36.989 | 59.528 | 37B | Route 131 – Odessa, Wellington | No eastbound entrance—eastbound entrance is via exit 38; signed as exit 37 westbound |
| Lafayette | Odessa | 38.252 | 61.561 | 38 | Johnson Drive | Westbound exit and eastbound entrance |
| Lafayette | ​ | 41.173 | 66.262 | 41 | Route M / Route O – Lexington, Mayview | |
| Lafayette | ​ | 45.382 | 73.035 | 45 | Route H – Mayview | |
| Lafayette | Higginsville | 49.387 | 79.481 | 49 | Route 13 – Higginsville, Warrensburg | Access to Wentworth Military Academy and Junior College, Missouri Veterans State Cemetery, Whiteman Air Force Base, the University of Central Missouri, Confederate Memorial State Historic Site, Battle of Lexington State Historic Site, and Maple Leaf Lake Conservation Area |
| Lafayette | ​ | 52.839 | 85.036 | 52 | Route T – Aullville | |
| Lafayette | Concordia | 58.569 | 94.258 | 58 | Route 23 – Concordia, Waverly, Knob Noster | |
| Saline | Emma | 62.574 | 100.703 | 62 | Route VV / Route Y – Emma | |
| Saline | Sweet Springs | 66.891 | 107.651 | 66 | Route 127 – Sweet Springs, Mt. Leonard | |
| Saline | ​ | 71.383 | 114.880 | 71 | Route EE / Route K – Houstonia | |
| Saline | ​ | 74.606 | 120.067 | 74 | Route YY | |
| Saline | ​ | 78.173 | 125.807 | 78 | US 65 – Sedalia, Marshall | Signed as exits 78A (south) and 78B (north) |
| Saline | ​ | 84.614 | 136.173 | 84 | Route J | |
| Cooper | ​ | 89.918 | 144.709 | 89 | Route K / Route M – Arrow Rock, Blackwater | |
| Cooper | ​ | 98.000 | 157.716 | 98 | Route 41 / Route 135 – Arrow Rock, Pilot Grove | |
| Cooper | Boonville | 101.781 | 163.801 | 101 | I-70 BL / US 40 / Route 5 (Ashley Road) – Boonville, Tipton | Eastern end of US 40 concurrency; access to Central Methodist University and Lake of the Ozarks |
| Cooper | Boonville | 103.551 | 166.649 | 103 | Route B (Main Street) – Boonville, Bunceton | Access to Historic Downtown Boonville and Katy Trail State Park |
| Cooper | Windsor Place | 106.382 | 171.205 | 106 | I-70 BL / Route 87 (Bingham Road) – Boonville, Prairie Home | |
| Cooper | ​ | 111.455 | 179.369 | 111 | Route 98 / Route 179 – Overton, Wooldridge | |
| Missouri River | Missouri River | 114.714 | 184.614 | Rocheport Interstate 70 Bridge | Rocheport Interstate 70 Bridge | Rocheport Interstate 70 Bridge |
| Boone | ​ | 115.505 | 185.887 | 115 | Route BB – Rocheport | Access to Katy Trail State Park and Historic Downtown Rocheport |
| Boone | ​ | 117.687 | 189.399 | 117 | Route J / Route O – Huntsdale, Harrisburg | |
| Boone | ​ | 121.178 | 195.017 | 121 | US 40 west / Route 240 / Route UU – Fayette | Western end of US 40 concurrency; access to Central Methodist University and UMC Dairy Farm |
| Boone | Columbia | 124.398 | 200.199 | 124 | Route E / Route 740 (Stadium Boulevard) – Columbia | Access to the University of Missouri, University Hospital, and Harry S. Truman Memorial Veterans' Hospital |
| Boone | Columbia | 125.543 | 202.042 | 125 | I-70 BL to West Boulevard | |
| Boone | Columbia | 126.545 | 203.654 | 126 | Route 163 (Providence Road) – Downtown | |
| Boone | Columbia | 127.019 | 204.417 | 127 | Route 763 (Range Line Road) | Access to Columbia College and Stephens College |
| Boone | Columbia | 128.287 | 206.458 | 128 | I-70 BL west – Columbia | Former westbound left exit and eastbound entrance. Both movements are now re-routed to Exit 128A. |
| Boone | Columbia | 128.887 | 207.424 | 128A | US 63 – Jefferson City, Moberly | Indirect access via I-70 Connector; access to Columbia Regional Airport and the University of Missouri |
| Boone | Columbia | 130.984 | 210.798 | 131 | St. Charles Road / Lake of the Woods Road | |
| Boone | ​ | 133.644 | 215.079 | 133 | Route Z – Centralia | |
| Callaway | ​ | 137.729 | 221.653 | 137 | Route DD / Route J – Millersburg | Access to Little Dixie Lake Conservation Area |
| Callaway | ​ | 144.193 | 232.056 | 144 | Route HH / Route M – Hatton | |
| Callaway | Kingdom City | 147.963 | 238.123 | 148 | US 54 – Auxvasse, Mexico, Fulton | Access to the Lake of the Ozarks, Mark Twain Lake, and the National Churchill Museum; future Diverging Diamond Interchange (DDI) |
| Callaway | ​ | 155.426 | 250.134 | 155 | Route A / Route Z – Bachelor, Calwood | |
| Callaway | ​ | 161.318 | 259.616 | 161 | Route D / Route YY – Williamsburg | Access to Whetstone Creek Conservation Area |
| Montgomery | ​ | 170.374 | 274.190 | 170 | Route 161 / Route J – Danville, Montgomery City | Access to Graham Cave State Park |
| Montgomery | New Florence | 174.975 | 281.595 | 175 | Route 19 – New Florence, Hermann | Access to Deutschheim State Historic Site and Mark Twain Lake |
| Montgomery | High Hill | 179.797 | 289.355 | 179 | Route F – High Hill | Access to Laborers-AGC Training Center |
| Montgomery | Jonesburg | 183.780 | 295.765 | 183 | Route E / Route NN / Route Y – Jonesburg | |
| Warren | ​ | 188.445 | 303.273 | 188 | Route A / Route B – Truxton | |
| Warren | Warrenton | 192.121 | 309.189 | 192 | Route MM / West Warrenton Boulevard | Roundabouts serve as access points to collector roads that direct to Route MM and Veterans Memorial Parkway; West Warrenton Boulevard serves as the overpass |
| Warren | Truesdale–Warrenton line | 193.484 | 311.382 | 193 | Route 47 – Warrenton, Hawk Point | |
| Warren | Wright City | 198.962 | 320.198 | 199 | Route H – Wright City | |
| Warren | Wright City | 200.000 | 321.869 | 200 | Route F / Route J / Route H – Wright City | Westbound exit and eastbound entrance; other half of interchange is via exit 199 |
| St. Charles | Foristell | 203.750 | 327.904 | 203 | Route T / Route W – Foristell | |
| St. Charles | Wentzville | 206.586 | 332.468 | 206 | David Hoekel Parkway | |
| St. Charles | Wentzville | 208.231 | 335.115 | 208 | Wentzville Parkway | Access to SSM Health St. Joseph Hospital — Wentzville |
| St. Charles | Wentzville | 209.412 | 337.016 | 209 | Route Z / Church Street | |
| St. Charles | Wentzville | 210.090– 211.002 | 338.107– 339.575 | 210 | US 61 (Avenue of the Saints) / I-64 east / US 40 east – Chesterfield, Hannibal | Eastern end of US 40 concurrency; signed as exits 210A (east/south) and 210B (north); I-64 exit 1; western terminus of I-64 |
| St. Charles | Lake St. Louis | 211.948 | 341.097 | 212 | Route A | Access to Midwest University |
| St. Charles | Lake St. Louis | 213.950 | 344.319 | 214 | Lake St. Louis Boulevard | Access to SSM Health St. Joseph Hospital-Lake St. Louis |
| St. Charles | O'Fallon | 215.977 | 347.581 | 216 | Bryan Road | |
| St. Charles | O'Fallon | 217.759 | 350.449 | 217 | Route K (Main Street) – O'Fallon | Eastbound exit and westbound entrance; westbound exit and eastbound entrance via frontage roads and exit 218 |
| St. Charles | O'Fallon | 218.433 | 351.534 | 218 | T.R. Hughes Boulevard / Belleau Creek Road Route K (Main Street) – O'Fallon | T.R. Hughes Boulevard and Belleau Creek Road signed eastbound only; Route K and Main Street signed westbound only |
| St. Charles | O'Fallon | 218.929 | 352.332 | 219 | T.R. Hughes Boulevard / Belleau Creek Road | Westbound exit and eastbound entrance; eastbound exit and westbound entrance via frontage roads and exit 218 |
| St. Charles | St. Peters | 220.381 | 354.669 | 220 | Route 79 – Elsberry, Louisiana | |
| St. Charles | St. Peters | 222.098 | 357.432 | 222A | Mid Rivers Mall Drive | |
| St. Charles | St. Peters | 222.262 | 357.696 | 222B | Veterans Memorial Parkway / Suemandy Drive | Eastbound exit only |
| St. Charles | St. Peters | 223.365– 223.945 | 359.471– 360.405 | 224 | Route 370 east | Route 370 exit 0 |
| St. Charles | St. Peters | 225.129 | 362.310 | 225 | Cave Springs Road / Harry S Truman Road | Access to Barnes Jewish Hospital-St. Peters |
| St. Charles | St. Charles | 226.933 | 365.213 | 227 | Zumbehl Road | |
| St. Charles | St. Charles | 228.277 | 367.376 | 228 | I-70 BL / Route 94 / Lewis and Clark Trail (First Capitol Drive) – St. Charles, Weldon Spring | Access to Lindenwood University and SSM Health St. Joseph Hospital-St. Charles |
| St. Charles | St. Charles | 229.143 | 368.770 | 229A | Convention Center Boulevard | No eastbound entrance |
| St. Charles | St. Charles | 229.379 | 369.150 | 229B | I-70 BL (Fifth Street) | Access to First Missouri State Capitol State Historic Site, Katy Trail State Park, and SSM Health St. Joseph Hospital-St. Charles |
| Missouri River | Missouri River | 230.128 | 370.355 | Blanchette Memorial Bridge | Blanchette Memorial Bridge | Blanchette Memorial Bridge |
| St. Louis | Maryland Heights | 231.507 | 372.574 | 231A | Route 141 south (Maryland Heights Expressway) | Access to Hollywood Casino Amphitheater |
| St. Louis | Maryland Heights | 231.507 | 372.574 | 231B | Route 141 north (Earth City Expressway) | Access to Hollywood Casino Amphitheater |
| St. Louis | Maryland Heights–Bridgeton line | 232.222– 233.024 | 373.725– 375.016 | 232 | I-270 – Chicago, Memphis | I-270 exit 20; signed as exits 232A (south) and 232B (north) westbound |
| St. Louis | Bridgeton | 234.180 | 376.876 | 234 | Route 180 (St. Charles Rock Road) | SSM Health DePaul Hospital-St. Louis |
| St. Louis | Bridgeton | 235.096 | 378.350 | 235 | US 67 (Lindbergh Boulevard) | Signed as exits 235A (south) and 235B (north) |
| St. Louis | Bridgeton | 235.626 | 379.203 | 235C | Route B (Natural Bridge Road) / Cypress Road | Access to St. Louis Lambert International Airport |
| St. Louis | Edmundson | 236.729 | 380.978 | 236 | Pear Tree Drive / Natural Bridge Road / Airflight Drive / Lambert International Boulevard | Access to St. Louis Lambert International Airport |
| St. Louis | Berkeley | 237.627 | 382.424 | 237 | Route 115 east (Natural Bridge Road) | No westbound exit |
| St. Louis | Berkeley | 238.068 | 383.133 | 238A | Lambert-St. Louis International Airport | Westbound exit and eastbound entrance |
| St. Louis | Berkeley | 238.430– 239.066 | 383.716– 384.739 | 238 | I-170 – Clayton | Signed as exits 238B (south) and 238C (north); I-170 exit 7 |
| St. Louis | Berkeley | 239.783 | 385.893 | 239 | Hanley Road | Westbound exit is via exit 240; access to Vatterott College |
| St. Louis | Cool Valley | 240.393 | 386.875 | 240 | Route N (Florissant Road / University Boulevard) / N. Hanley Road | North Hanley Road not signed eastbound; access to Historic Downtown Ferguson and the University of Missouri-St. Louis |
| St. Louis | Normandy | 240.920 | 387.723 | 241A | Bermuda Road | |
| St. Louis | Northwoods–Norwood Court line | 241.691 | 388.964 | 241B | Route U (Lucas & Hunt Road) | |
| St. Louis | Pine Lawn | 242.774 | 390.707 | 242 | Jennings Station Road | |
| City of St. Louis | City of St. Louis | 243.09 | 391.22 | 243A | Goodfellow Boulevard | Eastbound access via exit 242 |
| City of St. Louis | City of St. Louis | 243.345 | 391.626 | 243B | Route 367 north (Riverview Boulevard) | Westbound exit only |
| City of St. Louis | City of St. Louis | 244.062 | 392.780 | 243C | Bircher Boulevard | Eastbound exit only |
| City of St. Louis | City of St. Louis | 244.255 | 393.090 | 244A | Union Boulevard / Kingshighway | Access to Ranken Technical College |
| City of St. Louis | City of St. Louis | | | — | I-70 Express Lanes – Downtown | Eastbound exit only; westbound entrance closed in 2009; western end of express lanes |
| City of St. Louis | City of St. Louis | 244.579 | 393.612 | 244B | Kingshighway Boulevard | Westbound exit and eastbound entrance; eastbound access via exit 244A |
| City of St. Louis | City of St. Louis | 245.013 | 394.310 | 245A | Shreve Avenue | |
| City of St. Louis | City of St. Louis | 245.643 | 395.324 | 245B | W. Florissant Avenue | |
| City of St. Louis | City of St. Louis | 246.111 | 396.077 | 246A | Carrie Avenue | Formerly signed as N. Broadway and O'Fallon Park |
| City of St. Louis | City of St. Louis | 246.622 | 396.900 | 246B | Adelaide Avenue | |
| City of St. Louis | City of St. Louis | 247.218 | 397.859 | 247 | Grand Boulevard | |
| City of St. Louis | City of St. Louis | 248.068 | 399.227 | 248A | Route 115 west (Salisbury Street) – McKinley Bridge | Access to IL 3 |
| City of St. Louis | City of St. Louis | 248.515 | 399.946 | 248B | Branch Street | Westbound exit only |
| City of St. Louis | City of St. Louis | 248.755 | 400.332 | 248C | St. Louis Avenue | Eastbound exit and entrance; access to Municipal River Terminal |
| City of St. Louis | City of St. Louis | 249.274 | 401.168 | 249A | I-44 west to I-55 south – Tulsa, Memphis | Eastbound exit and Westbound entrance; eastern terminus of I-44; former routing of I-70 |
| City of St. Louis | City of St. Louis | 249.335 | 401.266 | 249B | Tucker Boulevard – Downtown | Signed as exit 249 westbound; no westbound entrance |
| City of St. Louis | City of St. Louis | 249.840 | 402.079 | 292B | Broadway | Eastbound exit only for Express Lanes; exit number based on I-44 mileage |
| City of St. Louis | City of St. Louis | | | | I-44 west to I-55 south – Tulsa, Memphis | Eastern end of Express Lanes; eastbound exit only for Express Lanes |
| Mississippi River | Mississippi River | 250.063 | 402.437 | Stan Musial Veterans Memorial Bridge; Missouri–Illinois line | Stan Musial Veterans Memorial Bridge; Missouri–Illinois line | Stan Musial Veterans Memorial Bridge; Missouri–Illinois line |
| Mississippi River | Mississippi River | 250.063 | 402.437 | | I-70 east to I-55 north / I-64 east – Indianapolis | Continuation into Illinois |
| 1.000 mi = 1.609 km; 1.000 km = 0.621 mi Closed/former Concurrency terminus Incomplete access Unopened |||||||

## Related routes
### Alternate route

* I-70 Alt.

### Business routes

* I-70 BL (Boonville)
* I-70 BL (Columbia)
* I-70 BL (St. Charles)

### Auxiliary routes

* I-170
* I-270
* I-470
* I-670