# List of defunct airlines of the United States (J–P)

The following is a list of defunct airlines of the United States. However, some of these airlines have ceased operations completely, changed identities and/or FAA certificates and are still operating under a different name (e.g. America West Airlines changed to use the identity of US Airways in 2005 – which itself also changed identity to American Airlines in 2015).
For reasons of size, this article is broken into four parts:
* List of defunct airlines of the United States (A–C)
* List of defunct airlines of the United States (D–I)
* List of defunct airlines of the United States (J–P)
* List of defunct airlines of the United States (Q–Z)
* J
* K
* L
* M
* N
* O
* P
* See also
* References
| Airline | State or territory | IATA | ICAO | Callsign | Hubs and focus cities | Commenced operations | Ceased operations | Notes |
| J ||||||||||
| Jamaire | Arkansas | | | | Harrell Field | 1979 | 1982 | |
| Janair | | | JAX | JANAIR | | 1988 | 1988 | |
| Janss Airways | Utah | | | | Salt Lake City | 1966 | 1969 | Renamed to Sun Valley Airlines |
| Jefferson | Minnesota | | | | Minneapolis | 1928 | 1928 | Operated Ford Trimotor |
| Jet 24 | Florida | TJ | JTS | | Miami | 1979 | 1986 | |
| Jet Alaska | Alaska | | | | Anchorage | 1985 | 1985 | |
| Jet America | California | SI | JET | | Long Beach | 1981 | 1987 | Merged into Alaska Airlines |
| Jet Aviation | | | BZF | BIZFLEET | | 1999 | 1999 | |
| Jet Charter | | | JCT | JET CHARTER | | 1997 | 1998 | |
| Jet Charter Jets | Nevada | | | | Las Vegas McCarran | 1994 | 1994 | |
| Jet Courier | Ohio | | DWW | DON JUAN | Cincinnati/Northern Kentucky | 1974 | 1985 | Renamed to Wright International Express |
| Jet East International | Texas | | JED | JET EAST | Dallas Love Field | 1983 | 2000 | Renamed to Express One International |
| Jet Express | Virginia | JI | JEX | JETEX | Charlottesville–Albemarle | 1983 | 1993 | Established as Bader Express. Become the last Midway Airlines |
| Jet Fleet International Airlines | Texas | | JFC | JET-FLEET | Dallas/Fort Worth | 1969 | 1992 | |
| Jet Freight Cargo | Florida | | JED | JET EAST | Miami | 1977 | 1980 | Renamed to Concord |
| Jet Hansa Corporation | Florida | XW | WRC | | West Palm Beach | 1967 | 1975 | Charter flights. Operated Hansa Jet. Renamed to Walker’s Cay Airlines |
| Jet U.S. | Michigan | | | | Detroit | 1993 | 1993 | Operated one week |
| Jet Way | Michigan | | JWY | | Willow Run | 1970s | 1984 | Acquired by Kalitta Air |
| JetAmerica | Florida | J1 | BSK | BISCAYNE | Toledo Express | 2007 | 2009 | As Air Azul |
| Jetstream International Airlines | Ohio | | VNA | JETSTREAM INTERNATIONAL | Dayton | 1983 | 1995 | Established as Vee Neal Airlines. Renamed to PSA Airlines |
| JetTrain | New York | | JTN | JETTRAIN | Newark Liberty | 1994 | 1996 | Established as AirTrain Airlines |
| JetWest | Colorado | | | | Denver | 1969 | 1970 | Absorbed by Frontier Airlines (1950–1986) |
| Jetwest International | California | | | | Los Angeles | 1994 | 1995 | Charter operator |
| Jetwest International Airways | Nevada | | | | Las Vegas McCarran | 1981 | 1982 | Renamed to Sunworld International |
| Jetwingsco | Florida | | | | Fort Myers | 2001 | 2004 | Operated Cessna Citation I, Gulfstream III |
| Jim Dodson Air Service | Alaska | | | | Anchorage | 1937 | 1943 | Acquired by Ray Petersen Flying Service |
| Jim Hankins Air Services | Mississippi | HQ | HKN | HANKINS | Jackson | 1958 | 2009 | |
| Johnson Airways | Louisiana | | | | New Orleans | 1932 | 1933 | Established as The Gulf Coast Airlines |
| Johnson Flying Service | Montana | JF | JF | JOHNSON SERVICE | Missoula | 1924 | 1975 | Sold to Evergreen Helicopters in 1975 to create Evergreen International Airlines |
| Jolly Voyager Travel Club | | | | | | 1970 | 1974 | Air travel club. Operated DC-7 |
| Juneau Air Service | Alaska | | | | Juneau | 1980 | 1980 | Renamed to Ward Air |
| Juneau Air Taxi Service | Alaska | | | | Juneau | 1953 | 1951 | Renamed to Loken Air Charter |
| K ||||||||||
| K-T Flying Service | Hawaii | | | | Honolulu | 1934 | 1941 | Founded by Charles Knox and Robert Tyce |
| Kahili Airlines (Trans National Airlines of Hawaii) | Hawaii | NX | | | Honolulu | 1979 | 1981 | |
| Kansas City Southern Skyways | Kansas | NX | | | Kansas City | 1945 | 1949 | Cargo carrier. Operated C-47 |
| Kenai Air Alaska | Alaska | | | | Kenai | 1978 | 1987 | Established as Kenai Air Service |
| Kenai Air Service | Alaska | | | | Kenai | 1977 | 1978 | Founded by Vernon L. Lofsted. Renamed to Kenai Air Alaska |
| Kenmore Air Harbor | Washington | | | | Kenmore | 1946 | 1981 | Renamed to Kenmore Air |
| KentuckySkies | Kentucky | | | | Owensboro–Daviess | 2009 | 2012 | A Pacific Wings subsidiary |
| Ketchikan Air Service | Alaska | 6S | | | Ketchikan | 1997 | 1998 | Acquired by Taquan Air |
| Ketchikan Airways | Alaska | | | | Ketchikan | 1933 | 1993 | Established as Pioneer Airways |
| Key Air | Utah | | KEY | KEY AIR | Salt Lake City | 1987 | 1989 | Charter carrier |
| Key Airlines | Idaho | | KWY | KEYAIR | Savannah/Hilton Head | 1969 | 1993 | Established as Thunderbird Airlines |
| Key West Airlines | Florida | | | | Key West | 1980 | 1981 | |
| Keyway Air Transport | | | | | Rhein-Main Air Base | 1986 | 1992 | |
| KeyWest Seaplane Service | Florida | | | | Key West | 1976 | 1997 | Adventure tours carrier. Operated Cessna 206 |
| King Airlines | Texas | | | | Wichita Falls | 1965 | 1972 | Commuter air services. Operated Aero Commander 680, Piper Aztec, Cherokee Six |
| Kingman Aviation | Arizona | | | | Kingman | 1973 | 1982 | |
| Kitty Hawk Aircargo | Indiana | KR | KHA | KITTYHAWK | Fort Wayne | 1985 | 2008 | Formed as Kitty Hawk Airways |
| Kitty Hawk Airways | Texas | 2K | KHA | | Dallas Love Field | 1978 | 1990 | |
| Kitty Hawk International | Michigan | CB | CKS | | Cincinnati/Northern Kentucky | 1999 | 2000 | To Kalitta Air |
| Kiwi International Air Lines | New Jersey | KP | KIA | KIWI AIR | Newark Liberty | 1992 | 1999 | Went bankrupt |
| Knowles Air-Ways | Michigan | | | | Flint | 1933 | 1935 | Operated Ford Trimotor |
| Kobrin Airways | New Jersey | | | | Princeton | 1982 | 1982 | Operated Piper Navajo |
| Kodiak Airways | Alaska | | | | Kodiak | 1960 | 1973 | Merged with Western Alaska Airlines |
| Kodiak Island Air | Alaska | | | | Kodiak | 1995 | 1998 | |
| Kodiak Western Alaska Airline | Alaska | | | | Kodiak | 1973 | 1982 | Formed by the merger of Kodiak Airways and Western Alaska Airlines. Operated Grumman Goose |
| L ||||||||||
| L.A.B. Flying Service | Alaska | JA | LAB | LAB | Haines | 1956 | 2008 | |
| L'Express Airlines | Louisiana | | LEX | LEX | New Orleans Louis Armstrong | 1989 | 1992 | |
| LA Helicopter | California | | | | Los Angeles | 1986 | 1989 | Operated Ecureuil 2 |
| La Posada Airways | Texas | | | | Laredo | 1967 | 1969 | Scheduled commuter services. Operated Britten-Norman Islander |
| Lake Central Airlines | Indiana | LC | | | Cleveland Hopkins | 1950 | 1968 | Began as Turner Airlines. To Allegheny Airlines |
| Lake Geneva Airways | Wisconsin | | | | Lake Geneva | 1970 | 1973 | |
| Lake Havasu Air Services | Arizona | | HCA | HAVASU | Lake Havasu City | 1970s | 1970s | Regional carrier |
| Lake State Airways | Minnesota | NT | | | New Ulm | 1977 | 1979 | Renamed to Midwest Aviation |
| Lake Union Air Service | Washington | | | | Lake Union Seaplane Base | 1946 | 1993 | To Kenmore Air |
| Lakeland Airlines | Wisconsin | YQ | LKL | LAKELAND | Rice Lake | 1980 | 1984 | |
| Laker Airways Inc. | Florida | 6F | LKR | LAKER | Fort Lauderdale | 1995 | 1999 | Was a US-registered airline established as a sister company to Laker Airways Bahamas |
| Lance Air Transport | Florida | | | | | 1962 | 1965 | Operated C-46, DC-6A, DC-7 |
| Landair International Airlines | | BN | C29 | | | 1994 | 1994 | Renamed to Forward Air International Airlines |
| Lang Aire | Nevada | | | | Las Vegas | 1994 | 1998 | Cargo carrier |
| Laredo Air | Texas | | LRD | LAREDO AIR | Laredo | 1988 | 1989 | |
| Larry’s Flying Service | | J6 | | | | 1982 | 2006 | |
| Las Vegas Airlines | Nevada | 6G | EER | | Las Vegas McCarran | 1973 | 1987 | |
| Laughlin Express | Nevada | | LEP | LAUGHLIN EXPRESS | Laughlin/Bullhead | 1992 | 1992 | |
| Lavery Airways | Alaska | | | | Fairbanks | 1935 | 1987 | Founded by William L. "Bill" Lavery. To Alaska Star Airlines |
| Lawrence Aviation | | | LAR | LAWRENCE | | 1992 | 1992 | |
| LB Ltd. | | LB | LAB | | | 1999 | 2000 | Established as Princess Vacations by Sir Freddie Laker. Renamed to the original Princess Vacations |
| Lear JeTravel | Nevada | | | | Reno Stead | 1968 | 1969 | Operated Learjet 23 and Learjet 24 |
| Lebanon Airport Development Corp. | New Hampshire | | LAD | LADCO-AIR | Lebanon | 1975 | 1976 | Operated Aero Commander |
| Leconte Airlines | | | LCA | LECONTE | | 1981 | 1981 | |
| Legend Airlines | Texas | LC | LGD | LEGENDARY | Dallas Love Field | 1996 | 2000 | Flights commenced in 2000; went bankrupt |
| Leisure Air | North Carolina | L8 | LWD | LEISURE WORLD | Chicago O'Hare | 1992 | 1995 | |
| Lemco Flying Services | | | | | | 1960 | 1964 | Renamed to Chatham Airlines |
| Liberty Air | Alaska | | | | Anchorage | 1984 | 1984 | Formed by the purchase and merger of Air North and Valdez Airlines |
| Liberty Airlines | Ohio | | | | Toledo Express | 1982 | 1983 | Operated Beech Baron and Convair 440 |
| Liberty Express Airlines | Pennsylvania | | | | Pittsburgh | 1994 | 1997 | To Air Midwest |
| Licon Airways | | | | | | 1933 | 1934 | |
| Lincoln Air Service | | | | | | 1928 | 1932 | |
| Lincoln Airlines | | | LUX | FREEBIRD | | 1989 | 1990 | |
| Lindsay Aviation | | | LSY | LINDSAY AIR | | 2004 | 2006 | |
| Lisle Air Service | California | | | | Fresno Chandler | 1965 | 1967 | Commuter services. Operated Cessna 206 |
| Livemercial Aviation | Delaware | | | | Wilmington | 2008 | 2012 | Charter carrier |
| Loening Air | Idaho | | | | Boise | 1963 | 1970 | Commuter service. Operated Cessna 411 |
| Loken Air Charter | Alaska | | | | Juneau | 1961 | 1964 | Established as Juneau Air Taxi Service. Merged with Channel Flying Service |
| Loken Aviation | Alaska | | | | Juneau | 1954 | 1997 | Renamed to Alaska Seaplanes |
| Lon’s Flying Service | Alaska | | | | Petersburg Johnson | 1967 | 1967 | Renamed to Alaska Island Air. Operated DHC-2 |
| Lone Star Air Cargo Lines | Texas | | | | Dallas Love Field | 1946 | 1947 | irregular air carrier |
| Lone Star Airlines | Texas | AD | LSS | LONESTAR | Dallas/Fort Worth | 1984 | 1998 | Established as Exec Express II |
| Long Island Airlines | New York | YL | ORA | LONG ISLAND | Farmingdale | 1987 | 1991 | Established as Montauk Caribbean Airways. Sold and renamed Executive Airlines |
| Longhorn Airlines | Texas | | | | Fort Worth Meacham | 1965 | 1971 | Commuter air services. Operated Piper Cherokee |
| LorAir | Arizona | | LOR | | Tucson | 1995 | 2001 | Charter carrier |
| Los Angeles Air Service | California | | | | Los Angeles | 1947 | 1960 | Supplemental air carrier. Renamed to Trans International Airlines |
| Los Angeles Air Taxi Service | California | | | | Los Angeles | 1965 | 1970 | Operated de Havilland Dove, Beech 18, Aero Commander 680 |
| Los Angeles Airways | California | | | | Grand Central Airport | 1927 | 1928 | |
| Los Angeles Airways | California | LX | | LOS ANGELES | Los Angeles | 1947 | 1971 | |
| Los Angeles-San Diego Air Line | California | | | | Los Angeles | 1925 | 1925 | Established by Ryan Airline. First scheduled airline in US |
| Louisa Flying Service | Virginia | | | | Louisa | 1995 | 2005 | |
| Louisiana Aircraft | New Mexico | | | | Albuquerque | 1941 | 2003 | Services for the U. S. Government. Renamed to Ross Aviation |
| Lubbock-Amarillo Armored Service | Texas | | | | Lubbock | 1967 | 1971 | Urgent deliveries carrier, Operated Piper Navajo |
| Lucerne Airways | California | | | | Oakland | 1931 | 1931 | |
| Ludington Airline | Pennsylvania | | | | Cleveland Hopkins | 1929 | 1933 | |
| Luthi Aviation | North Dakota | | | | Fargo | 1972 | 1974 | Operated Beech C-45, Renamed to Sizer Airways |
| Lynch Flying Service | Montana | | LCH | LYNCH AIR | | 1967 | 1996 | Commuter services. Operated Cessna 310, Cessna 337 |
| Lynx Air International | Florida | | LXF | LYNX FLIGHT | Fort Lauderdale | 1989 | 2009 | |
| Lynx Aviation | Colorado | L3 | SSX | SHASTA | Denver | 2006 | 2011 | |
| M ||||||||||
| Mac Dan Aviation | New Jersey | | MCN | MAC DAN | Caldwell | 2004 | 2006 | |
| MAC Helicopters | Texas | | | | | 1973 | 1973 | |
| MAC McMullen Airways | Florida | | | | Tampa | 1920 | 1931 | Daily passenger services. Operated Stinson |
| Mackey Airlines | Florida | MK | MK | | Fort Lauderdale | 1953 | 1967 | To Eastern Air Lines. Founder started Mackey International in 1968 |
| Mackey International | Florida | MI | MI | | Fort Lauderdale | 1968 | 1981 | DBA Mackey International Air Taxi, then Mackey International Air Commuter then Mackey International Airlines |
| Maddux Air Lines | California | | | | Mines Field | 1927 | 1929 | Merged with Transcontinental Air Transport to form TAT Maddux Air Lines |
| Magic Carpet Air | | | | | | 1961 | 1972 | Air travel club. Renamed to Traventure Air Travel Club. Operated Convair 440 |
| Mahalo Air | Hawaii | BM | MLH | MAHALO | Honolulu | 1993 | 1997 | |
| Main Flying Services | | | | | | 1930 | 1931 | |
| Maine Air | Maine | | | | Bangor | 1982 | 1983 | Operated Piper Aircraft |
| Maine Air Cargo Express | Maine | | | | | 1948 | 1949 | |
| Maine Air Transport | Maine | | MAT | MAINE AIR | | 1932 | 1933 | |
| Maine Aviation | Maine | | MAT | | Portland Jetport | 1962 | 2002 | |
| Maine Coast Airways | Maine | | | | | 1983 | 1992 | |
| Maine State Airways | Maine | | | | Augusta | 1931 | 1931 | |
| Majestic Air | Florida | QT | PIA | | Miami | 1988 | 1989 | Renamed to Carnival Air Lines. Operated a single Boeing 707-100 |
| Majestic Airlines | Utah | 2J | MAJ | MAGIC AIR | Salt Lake City | 1988 | 1997 | Operated Beech 99 |
| Makani Kai Air | Hawaii | | | | Honolulu | 1998 | 2020 | Merged into Mokulele Airlines |
| Mall Airways | New York | GH | MLS | MALL AIRWAYS | Albany | 1973 | 1989 | Merged into Business Express Airlines |
| Mamer Air Transport | Washington | | | | Felts Field | 1929 | 1932 | Operated Ford Trimotor |
| Manhattan Airlines | New York | | | | Syracuse | 1974 | 1976 | Operated DC-3 |
| Mannion Air Charter | Michigan | | | | Willow Run | 1950s | 1980s | Operated DC-3 and Beech C-45 |
| Manufacturers Air Transport | Illinois | | | | Chicago Midway | 1967 | 1973 | Operated C-47, Cessna 206 and Cessna 310 |
| Marco Island Airways | Florida | LS | | | Miami | 1973 | 1986 | Merged into Provincetown-Boston Airlines |
| Marine Airways | Alaska | | | | Juneau | 1936 | 1939 | Merged with Alaska Air Transport to form Alaska Coastal Airlines |
| Mario’s Air | Florida | M2 | | | Miami-Opa-locka | 1995 | 2006 | Operated DC-3 |
| MarkAir | Alaska | BF | MRK | MARKAIR | Anchorage | 1946 | 1995 | Merged into Northern Air Cargo |
| Markair Express | Alaska | 2E | MRX | SPEEDMARK | Bethel | 1974 | 1996 | Established as Hermens Air. Acquired by MarkAir in 1987 |
| Marquette Airlines | | | | | | 1938 | 1941 | To Trans World Airlines |
| Marsh Airways | Alaska | | | | Bethel | 1934 | 1935 | Founded by Ray Petersen |
| Marshfield Aviation | Massachusetts | | | | Marshfield | 1967 | 1971 | Operated Cessna 172, Cessna 177 Cardinal, Cessna 337 |
| Martz Air Lines | New York | | | | Buffalo Niagara | 1930 | 1933 | Absorbed by American Airways |
| Maryland Airways | Maryland | | | | | 1964 | 1968 | Operated Beech 18 |
| Mason & Dixie Air Lines | Michigan | | | | Detroit | 1929 | 1931 | |
| Mass Air | Massachusetts | | | | Boston | 1964 | 1971 | Founded by E. Antony. Acquired and merged intoExecutive Airlines |
| Massachusetts Airlines | Massachusetts | | | | Boston | 1949 | 1949 | |
| MATS Cargo Airlines | Illinois | | | | Chicago O'Hare | 1972 | 1973 | Scheduled and charter cargo operator |
| Matson Airlines | California | | | | San Francisco | 1946 | 1948 | Operated DC-4 |
| Maui Airlines | Hawaii | | | | Kahului | 1985 | 1988 | |
| Mauiva Air Tours | Florida | | | | Kissimmee | 2010 | 2014 | Renamed ViaAir. Operated Embraer Brasilia |
| Maverick Airways | Texas | | | | Maverick County | 1974 | 1976 | |
| Maverick Airways | Colorado | | | | Denver | 1996 | 1997 | Founded by Cody Diekroeger. Operated DHC 7 |
| Maverick International | New York | YG | | | New York Stewart | 1977 | 1979 | Operated three Boeing 707. Transported cattle to Iran |
| Mavrik Aire | Alaska | | | | Kenai | 1998 | 2007 | Bush charter services |
| Max's Air Service | Wisconsin | | | | Appleton | 1947 | 1967 | Founded by Max Sagunsky. Renamed to Maxair |
| MAXjet Airways | Virginia | MY | MXJ | MAX-JET | Washington Dulles | 2003 | 2007 | |
| May Air Xpress | Texas | | MXP | BEECHNUT | | 1990 | 2004 | Founded by Thomas W. May |
| Mayflower Airlines | Massachusetts | | | | Boston | 1936 | 1945 | Absorbed by Northeast Airlines |
| McClain Airlines | Arizona | | | | Phoenix Sky Harbor | 1984 | 1987 | |
| McCollum Aviation | Illinois | | | | | 1939 | 1986 | |
| McCulloch International Airlines | California | | | | Long Beach | 1970 | 1977 | McCulloch Properties bought Vance International Airways and merged w/ own operation. |
| McCulloch Properties | California | | | | Long Beach | 1964 | 1970 | Aircraft had "Lake Havasu City" titles. Merged into McColluch International Airlines. |
| McGee Airways | Alaska | | | | Anchorage | 1932 | 1934 | Merged with Star Air Service |
| McKinley Air Service | Alaska | | | | Talkeetna | 2003 | 2003 | Operated Cessna 185 |
| Mel Air | | | | | | 1963 | 1971 | Operated Cessna 402, Piper Aztec, Piper Apache |
| Mercer Airlines | California | | | | Burbank | 1950s | 1975 | intrastate airline and uncertificated carrier. Became Pacific American Airlines in 1975. |
| Mercury Air Lines | California | | | | West Los Angeles | 1919 | 1921 | Operated Junkers-Larsen JL-6 |
| Mercury Airlines | Texas | | | | Houston-Hobby | 1946 | 1947 | |
| Meridian Air Cargo | | | | | | 1975 | 1979 | Established as Key Brothers Flying Service |
| Merlin Express | Texas | | MEI | | San Antonio | 1996 | 2000 | Established as SAT-Air. Renamed to Merlin Airways. Operated Swearingen Metroliner |
| Merrimack Air System | Massachusetts | | | | Lawrence | 1975 | 1978 | Moved to Bedford and renamed to Merimack Airlines |
| Merrimack Airlines | Massachusetts | ZE | | | Hanscom Field | 1978 | 1980 | Merged with New Jersey Airlines |
| Mesaba Airlines | Tennessee | XJ | MES | MESABA | Memphis | 1944 | 2012 | Merged into Pinnacle Airlines |
| Methow Aviation | Washington | | MER | METHOW | | 1989 | 2006 | |
| MetJet | Wisconsin | | | | Green Bay–Austin Straubel | 2013 | 2013 | |
| Meteor Air Transport | New York | | | | Teterboro | 1946 | 1958 | Supplemental air carrier; ceased operation after IRS seized assets. |
| Metro Air Northeast | New York | SS | MNE | NORTHEAST | Plattsburgh | 1989 | 1991 | |
| Metro Airlines | Texas | | | | Clear Lake City STOLport | 1969 | 1993 | Originally Houston Metro Airlines |
| Metroflight Airlines | Texas | | | | Clear Lake City STOLport | | 1993 | Part of Metro Airlines |
| Metro Express II | | | MEX | EAGLE EXPRESS | | 1984 | 1995 | Established as Eastern Metro Express. Operated Jetstream 31 |
| Metro Express Airlines | Georgia | | EME | EASTERN METRO | Atlanta | 1984 | 1991 | |
| Metro International Airlines | New York | FT | | | New York Kennedy | 1980 | 1983 | Passenger division of Flying Tiger Line. Operated Boeing 747 |
| MetroJet | Virginia | US | USA | USAIR | Baltimore–Washington | 1998 | 2001 | |
| Metropolitan Air Ferry Service | New York | | | | Newark | 1931 | 1931 | Operated Ford Trimotor |
| MGM Grand Air | California | MG | MGM | GRAND AIR | Minneapolis–Saint Paul | 1987 | 1995 | To Champion Air |
| Miami Air Charter | Florida | | HUR | HURRICANE CHARTER | Miami | 1987 | 1995 | Renamed to Nations Air Express |
| Miami Air International | Florida | LL | BSK | BISCAYNE | Miami | 1990 | 2020 | |
| Miami Air Lease | Florida | MG | MGD | MIAMI AIR | Miami | 1999 | 1999 | |
| Miami Airlines | Florida | | | | Miami | 1960 | 1961 | |
| Miami Executive Aviation | Florida | | | | Miami | 1997 | 1999 | |
| Miami Seaplane Service | Florida | | | | Miami Seaplane Base | 1933 | 1933 | |
| Miami Valley Aviation | Ohio | | OWL | NIGHT OWL | Middletown | 1998 | 2006 | Established as Hoganair |
| Miami-Key West Airways | Florida | | | | Miami | 1937 | 1938 | |
| Michigan Air Express | Michigan | | | | | 1930 | 1931 | |
| Michigan Airways | Michigan | | | | | 1982 | 1989 | Established as Emmet County Aviation. Acquired by Drummond Island Air |
| Michigan Central Airlines | Michigan | | | | Bishop | 1938 | 1938 | |
| Michigan Peninsular Airways | Michigan | | | | Willow Run | 1978 | 1981 | Operated DC-8 |
| Michigan Trade Winds | Michigan | | | | | 1968 | 1968 | |
| Mid Pacific Air | Hawaii | HO | MPA | MID PAC | Honolulu | 1981 | 1995 | |
| Mid Pacific Cargo | Indiana | PF | MPA | | Lafayette | 1999 | 1999 | |
| Mid South Airways | | | | | | 1940 | 1940 | |
| Mid-America Airlines | Illinois | | | | Peoria | 1970 | 1970 | Operated Martin 2-0-2 |
| Mid-American Air Transport | Kansas | | | | | 1967 | 1971 | Operated Beech 18 |
| Mid-Atlantic Freight | North Carolina | | MDC | NIGHT SHIP | Piedmont Triad | 1990 | 2005 | Acquired by Martinaire in 2005 |
| Mid-Coast Airways | Maine | | | | Rockland | 1960 | 1968 | Renamed to Downeast Airlines |
| Mid-Continent Air Express | Colorado | | | | Denver Stapleton | 1929 | 1931 | Operated Fokker Super Universal. Acquired by Western Air Express |
| Mid-Continent Airlines | Iowa | | | | Sioux Gateway | 1938 | 1952 | Established as Hanfords Tri-State Airlines in 1928. Acquired by Braniff |
| Mid-Continent Airlines | | | | | | 1964 | 1964 | |
| Mid-Continent Airlines | Tennessee | | | | Memphis | 1969 | 1970 | Operated Cessna 402 |
| Mid-Continent Airlines | Oklahoma | | | | Halliburton Field | 1972 | 1974 | Operated Piper Aircraft |
| Mid-Continent Airlines | | | | | | 1980 | 1982 | Funded by Terry Hudik and Mike Gedmin. Renamed to American Central Airlines |
| Mid-Hudson Airline | | | | | | 1951 | 1966 | Renamed to Command Airways |
| Mid-South Airlines | | | | | | 1979 | 1983 | Established as Resort Commuter Airlines. Renamed to Air Virginia |
| Mid-West Airways | Iowa | | | | Des Moines | 1929 | 1931 | Renamed to Des Moines Airways |
| Mid-West Airlines | Iowa | | | | Des Moines | 1949 | 1952 | Local service airline, briefly owned by Purdue University. Completely unrelated to the later Midwest Airlines of Wisconsin. |
| MidAtlantic Airways | Pennsylvania | BK | PDC | | Pittsburgh | 2002 | 2006 | |
| Midcontinent Airlines | Nebraska | CT | MCA | CONTINAIR | Omaha | 1986 | 1989 | Began as AAA Airlines. Operated as Braniff Express |
| Midet Aviation | Florida | | | | Palm Beach | 1938 | 1956 | Acquired by Mackey Airlines |
| Midnight Express | Georgia | | | | Atlanta | 1983 | 1988 | |
| Midstate Airlines | Wisconsin | IU | MIS | MIDSTATE | Central Wisconsin | 1964 | 1989 | To Sentry Insurance |
| Midway Airlines (1976–1991) | Illinois | ML | MDW | MIDWAY | Chicago Midway | 1976 | 1991 | |
| Midway Connection | Illinois | | XAP | MID-TOWN | Chicago Midway | 1987 | 1991 | |
| Midway Metrolink | Illinois | | | | Chicago Midway | 1983 | 1985 | Operated DC-9-30 |
| Midway Express | Florida | | FLA | PALM | Miami | 1984 | 1990 | Operated former Air Florida Boeing 737 |
| Midway Airlines (1993–2003) | North Carolina | JI | MDW | MIDWAY | Chicago Midway | 1993 | 2003 | |
| Midway Aviation | Texas | | | | Dallas Love Field | 1996 | 1996 | Acquired by Airnet Express |
| Midwest Air Charter | Ohio | | | | Willoughby | 1977 | 1980 | Acquired by Airborne |
| Midwest Airlines | Wisconsin | YX | MEP | MIDEX | Milwaukee Mitchell | 2002 | 2010 | Merged with Frontier Airlines, completely unrelated to earlier Mid-West Airlines. |
| Midwest Connect | Wisconsin | | | | Milwaukee Mitchell | 1994 | 2010 | Regional airline associate of Midwest Airlines |
| Midwest Express | Wisconsin | | | | Milwaukee Mitchell | 1978 | 2002 | Originally K-C Aviation, renamed to Midwest Airlines |
| Midwest Airways | Ohio | | | | Lunken Field | | | |
| Midwest Aviation | Minnesota | | | | New Ulm | 1973 | 1983 | Operated as Air New Ulm (1973–1977), then as Lake State Airways (1977–1999) |
| Midwest Commuter Airlines | Indiana | | | | Indianapolis | 1967 | 1974 | |
| Militair | | | | | | 1979 | 1980 | Operated American Eagle Boeing 707 to fly military families |
| Million Air Monterey | California | | | | Salinas | 1999 | 2012 | Established as Air Trails. Operated Cessna Citation II, Learjet 35A |
| Millon Air | Florida | OX | OXO | MILL AIR | Miami | 1983 | 1998 | Operated Boeing 707, CL-44 |
| Mission Airlines | California | | | | Gillespie Field | 1969 | 1982 | Operated Beech 18 |
| Mississippi Valley Airlines | Wisconsin | XV | MVA | VALAIR | Quad City | 1968 | 1985 | Merged with Air Wisconsin |
| Missouri Air Commuter | Missouri | | | | Kansas City | 1974 | 1978 | Charter and air taxi. Operated Martin 4-0-4 |
| Modern Air Transport | New Jersey | KV | | MODERN | Newark Liberty | 1946 | 1975 | |
| Mohawk Airlines | New York | MO | | MOHAWK | Utica, New York | 1945 | 1972 | As Robinson Airlines, to Allegheny Airlines |
| Mokulele Flight Service | Hawaii | | | | Kona | 1998 | 2005 | Rebranded as Mokulele Airlines |
| Monarch Air | Texas | | | | Dallas Addison | 1986 | 2017 | Founded by the Sawtelle family. Operated Cessna Skyhawk |
| Monarch Air Lines | Colorado | | | | Denver | 1946 | 1950 | Merged with Arizona Airways and Challenger Airlines to form Frontier Airlines |
| Monarch Aviation | Florida | | | | Miami | 1977 | 1982 | |
| Montauk Caribbean Airways | New York | YL | ORA | | Farmingdale | 1960 | 1987 | Sold and renamed Long Island Airlines |
| Morris Air | Utah | KN | MSS | WASATCH | Salt Lake City | 1948 | 1994 | As Morris Air Service, to Southwest Airlines |
| Mountain Air Express | Colorado | M7 | MAX | PIKES PEAK | Denver | 1996 | 1998 | Sold to Air Wisconsin, formerly owned by Western Pacific Airlines |
| Mountain Airways | New York | | | | Kingston–Ulster | 1969 | 1970 | Operated BN Islander |
| Mountain Aviation | Alaska | | | | Sitka | 1977 | 1995 | Operated amphibious Cessna 185, DHC Beaver |
| Mountain West Airlines | Idaho | FX | | | Boise | 1979 | 1981 | |
| Mountain West Airlines | Arizona | | | | Phoenix Sky Harbor | 1995 | 1996 | To Mesa Airlines |
| Mountainwest Aviation | Arizona | | | | Tucson | 1967 | 1981 | Acquired Sierra Pacific Airlines, Operated Convair 580 |
| MPA Michigan Peninsula Airlines | Michigan | MN | XAT | | Willow Run | 1979 | 1984 | Cargo operator |
| Munz Northern Airlines | Alaska | | | | Nome | 1974 | 1983 | |
| Mt. McKinley Air Freight | Alaska | | | | Anchorage | 1946 | 1949 | Operated C-47A |
| Murray Air | Michigan | 5M | MUA | | Oakland County | 1986 | 2008 | Rebranded as National Airlines (N8) |
| Muse Air | Texas | MC | TST | MUSE AIR | Dallas Love Field | 1981 | 1986 | Acquired by Southwest Airlines and renamed TranStar Airlines |
| Mustang Airlines | Texas | | | | Dallas | 1967 | 1977 | |
| Mutual Air Lines | California | | | | Los Angeles | 1928 | 1929 | Operated Ryan Brougham |
| Myrtle Beach Jet Express | South Carolina | | | | Myrtle Beach | 1996 | 1999 | |
| N ||||||||||
| Nantucket Airlines | Massachusetts | | ACK | ACK AIR | Hyannis | 1986 | 1989 | Merged with Cape Air |
| Nantucket Shuttle | Massachusetts | | | | Hyannis | 2006 | 2011 | Founded as Horizon Air Charter. Acquired by Island Airlines |
| Napier Air Service | Alabama | | NAP | NAPIER | Dothan | 1948 | 1991 | |
| Naples Airlines | Florida | | | | Naples | 1960 | 1980 | Merged into Provincetown-Boston Airlines |
| Nashville Eagle | Tennessee | | | | Nashville | 1987 | 1991 | Acquired AVAir. Merged with Command Airways to become Flagship Airlines |
| National Air Transport | Illinois | | | | Chicago Midway | 1925 | 1934 | |
| National Airlines (1934–1980) | Florida | NA | NA | NATIONAL | Miami | 1934 | 1980 | Merged into Pan American World Airways |
| National Airlines (1983–1985) | | OV | NAN | NATION AIR | | 1983 | 1985 | dba for United Air Carriers, which flew 1982–1983 as "Overseas National Airways" |
| National Airlines (1999–2002) | Nevada | N7 | ROK | RED ROCK | Las Vegas McCarran | 1999 | 2002 | |
| National Airlines / Private Jet Expeditions | Kansas | 5J | PJE | Pee Jay | Atlanta | 1994 | 1995 | |
| National Airways | Massachusetts | | | | Boston | 1931 | 1940 | Founded by Paul Collins, Sam Solomon, Amelia Earhart. Operated 2 Stinson Airliner. To Delta Air Lines |
| National Commuter Airlines | Florida | | | | Miami | 1982 | 1984 | Acquired by Air Florida |
| National Executive Flight Service | Massachusetts | | | | Boston | 1960 | 1967 | Renamed to Executive Airlines |
| National Florida Airlines | Florida | | NFA | VOYAGER | Daytona Beach | 1981 | 1983 | |
| National Freight Service | California | | | | Los Angeles | 1945 | 1949 | Renamed to Flying Tigers Airlines. Operated Budd Conestoga, C-46 |
| National Parks Airways | Idaho | | | | Salt Lake City | 1927 | 1937 | Bought by Western Airlines |
| National Skyway Freight Corporation | California | | | | Los Angeles | 1945 | 1946 | Operated Budd Conestoga. Renamed to Flying Tiger Line |
| Nations Air | Pennsylvania | N5 | NAE | NATIONS EXPRESS | Pittsburgh | 1995 | 1998 | |
| Nationwide Air Transport Service | Florida | | | | Miami | 1946 | 1951 | Cargo carrier |
| Nationwide Airlines | Michigan | | | | Detroit | 1947 | 1952 | Air mail and passenger service |
| Nationwide Airlines Southeast | Georgia | | | | Atlanta | 1969 | 1978 | Name changed to Air South (Georgia) |
| Navajo Airlines | Arizona | | | | Winslow | 1930 | n/a | Operated Kreutzer Air Coach |
| Nenana Fuel Company | Alaska | | | | Fairbanks | 1958 | 1992 | Cargo carrier. Operated C-46, DC-3 |
| Nevada Airlines | California | | | | Los Angeles Grand Central | 1929 | 1929 | Operated four Lockheed Vega |
| Nevada Airlines | Nevada | | | | | 1963 | 1962 | Established as Blatz Airlines. Succeeded by Hawthorne-Nevada Airlines in 1964 |
| New England Air Express | New Jersey | | | | Teterboro | 1949 | 1952 | Irregular air carrier shut by CAB in 1952 for mistreating passengers |
| New England Air Transport | Maine | | | | | 2008 | 2009 | |
| New England Central Airways | Massachusetts | | | | Boston | 1946 | 1947 | Operated Cessna Bobcat |
| New England Commuter | New Hampshire | | | | Manchester–Boston | 1971 | 1971 | Operated Cessna 402 |
| New England & Western Air Transportation Co. | Massachusetts | | | | Westfield-Barnes | 1930 | 1930 | |
| New Haven Airways | Connecticut | | | HAVEN AIR | Tweed New Haven | 1978 | 1980 | Renamed to NewAir |
| New Jersey Airways | | | | | | 1977 | 1980 | Merged into Merrimack Airlines |
| New Mexico Airlines | Arizona | LW | NMI | TSUNAMI | Albuquerque | 2007 | 2015 | A Pacific Wings subsidiary |
| New Orleans Air Lines | Louisiana | | | | New Orleans Lakefront | 1931 | 1931 | |
| New York & Western Airlines | New York | | | | Newark Liberty | 1931 | n/a | Subsidiary of Pittsburgh Airlines |
| New York Air | New York | NY | NYA | APPLE | New York-LaGuardia | 1980 | 1987 | To Continental Airlines |
| New York Air Connection | New York | NY | NYA | APPLE | New York-LaGuardia | 1985 | 1987 | Routes feeding New York Air |
| New York Airways | New York | NY | NYA | NEW YORK | New York-LaGuardia | 1949 | 1979 | Helicopter services |
| New York Helicopter | New York | HD | NYH | | East 34th Street Heliport | 1980 | 1988 | |
| New York Safety Airlines | New York | | | | Roosevelt Field | 1929 | 1930 | Established as Tri-Motor Safety Airlines. Acquired by New York, Rio, and Buenos Aires Line |
| New York-Newport Air Service | New York | | | | Newark Liberty | 1922 | 1923 | |
| New York, Philadelphia & Washington Airways | New York | | | | Newark Liberty | 1929 | 1934 | Acquired by Eastern Air Transport |
| New York, Rio, and Buenos Aires Line | New York | | | | New York Curtiss | 1929 | 1930 | To Pan American World Airways |
| NewAir | Connecticut | | | | Tweed New Haven | 1980 | 1990 | Established as New Haven Airways |
| Niemeyer Aviation | Indiana | | | | | 1972 | 1999 | Founded by Don Neimeyer. Operated Grumman AA-5 Tiger |
| Noland-Decoto Flying Service | Washington | | | | Yakima | 1966 | 1998 | Charter, aerial photography, ambulance service |
| Nomads Travel Club | Michigan | | | | Detroit Metro | 1965 | 2011 | Oldest air travel club. Operated 727-200 |
| Nome Flying Service | Alaska | | | | Nome | 1971 | 1979 | |
| North American Airlines | California | | | | Lockheed Air Terminal | 1952 | 1956 | Name of Twentieth Century Airlines 1952–1956. Part of North American Airlines Group |
| North American Airlines | Florida | | | | Miami | 1980 | 1982 | Established as Air Miami. Operated CASA 212 |
| North American Airlines | Georgia | NA | NAO | NORTH AMERICAN | Tampa | 1989 | 2014 | Went bankrupt |
| North American Airlines Group | California | | | | Lockheed Air Terminal | 1949 | 1957 | A combine: rogue virtual airline flying as "North American". "Trans American" 1956–1957 |
| North American Airways | Wisconsin | | | | Appleton | 1930s | 1930s | Operated Stinson Detroiter |
| North Central Airlines | Wisconsin | NC | | NORTH CENTRAL | Chicago O'Hare | 1944 | 1979 | Merged with Southern Airways to form Republic Airlines (1979-1986) |
| North Continent Airlines | California | | | | Long Beach | 1983 | 1991 | Operated Hamilton Westwind III, Beech 1900, Twin Otter |
| North Pacific Airlines | Alaska | | | | Anchorage | 1983 | 1992 | Founded by Roy Musgrove |
| North Pacific Airlines | Washington | | | | Seattle–Tacoma | 1987 | 1991 | Merged with WestAir Commuter Airlines |
| North Slope Supply Company | Alaska | | | | Anchorage | 1969 | 1969 | Went bankrupt |
| North South Airways | Georgia | SPK | | SPK | Statesboro | 1983 | 2003 | Founded as Diamond Aviation |
| North Star Air Cargo | Alaska | | SBX | SKY BOX | Anchorage | 1989 | 2008 | |
| North Star Group | New York | | | | New York-LaGuardia | | | 1950s combine. Aircraft shown is Caribbean American Lines |
| Northcoast Executive Airlines | Ohio | 5N | NCE | TOP HAT | Dayton | 1990 | 1991 | |
| Northeast Airlines | Massachusetts | NE | DOW | NORTHEAST | Boston | 1940 | 1972 | Founded 1931 as Boston-Maine Airways, merged into Delta Air Lines |
| Northeast Airlines | Maine | | NEE | NORTHEAST | Portland Jetport | 1997 | 1999 | Began as Downeast Express |
| Northeast Express Regional Airlines | New Hampshire | 2V | NEE | | Manchester–Boston | 1974 | 1994 | Went bankrupt |
| Northeastern International Airways | Florida | QS | QSA | NORTHEASTER | Fort Lauderdale-Hollywood | 1982 | 1986 | |
| Northern Air Service | Alaska | | | | | 1930 | 1930 | |
| Northern Air Transport | Alaska | | | | | 1924 | 1926 | Renamed to Wien Airways of Alaska |
| Northern Airlines | North Dakota | | | | Minot | 1928 | 1929 | |
| Northern Airlines | Ohio | | | | St. Marys | 1968 | 1970 | Operated Beech 18, Twin Otter |
| Northern Airlines | Minnesota | | | | St. Paul Downtown | 1981 | 1982 | Filed for bankruptcy |
| Northern Consolidated Airlines | Alaska | | | | Anchorage | 1947 | 1968 | Merged into Wien Airways of Alaska. Operated DC-3, Short Skyvan |
| Northern Illinois Commuter Airlines | Illinois | | NIC | ILLINOIS COMMUTER | | 1979 | 1980 | Operated Beech 99 |
| Northern International Airlines | New York | | | | New York Kennedy | 1954 | 1966 | Renamed to Direct Airlines |
| Northern Star Airlines | Illinois | UO | XAP | MID TOWN | Chicago Gary | 1994 | 1995 | Reorganized as Northern Star Airlines |
| Northwest Airlines | Minnesota | NW | NWA | NORTHWEST | Minneapolis–Saint Paul | 1934 | 2010 | Formed 1926 as Northwest Airways, merged into Delta Air Lines |
| Northwest Orient Airlines | Minnesota | NW | NWA | NORTHWEST | Minneapolis–Saint Paul | | | Renamed to Northwest Airlines |
| Northwest Airlink | Minnesota | | NWX | FLAG SHIP | Minneapolis–Saint Paul | 1984 | 2010 | |
| Northwest Sky Ferry | Washington | | | | Friday Harbor | 2007 | 2014 | Established as Rugby Aviation in 1999. Merged into San Juan Airlines |
| O ||||||||||
| Oahu & Kauai Airlines | Hawaii | | | | Honolulu | 1976 | 1976 | Operated Cessna 402 |
| Oak Harbor Airlines | Washington | | | | Oak Harbor | 1971 | 1974 | Renamed to Harbor Airlines |
| Ocean Airways | Florida | | | | | 1980 | 1980 | |
| Ocean Reef Airways | Florida | | | | Key Largo | 1970 | 1982 | Merged into Provincetown-Boston Airlines |
| Ocean Wings | Massachusetts | | TUK | TUCKERNUCK | Nantucket | 1990 | 2002 | To Island Airlines |
| Ocean Air Tradeways | New York | | | | | 1946 | 1950 | Original name of United States Overseas Airlines |
| Oceanair | Puerto Rico | | TJ | | | 1970s | 1980s | To Trans Commuter Airline |
| Odyssey Transport | Nevada | | | | Las Vegas McCarran | 1998 | 2002 | Cargo operator |
| Okair (Oaha and Kauai Airlines) | Hawaii | YQ | | | Honolulu | 1975 | 1980 | |
| Oklahoma Short Line Airways | Oklahoma | | | | Tulsa | 1930 | 1931 | Founded by L H Atkinson. Operated Ryan Brougham |
| Oklahoma-Texas Air Line | Oklahoma | | | | Oklahoma City | 1929 | 1932 | |
| Olson Air Service | Alaska | 4B | | | Nome | 1987 | 2006 | |
| Omaha Aviation Commuter | Nebraska | | | | Omaha | 1979 | 1980 | |
| Omega Air Cargo | Florida | | | | Fort Lauderdale–Hollywood | 2004 | 2004 | Renamed to Focus Air Cargo |
| Omni Air Express | Oklahoma | | | OMNI-EXPRESS | Tulsa | 1993 | 1997 | Renamed Omni Air International |
| Omni Airlines | Arizona | OE | | | Flagstaff Pulliam | 1977 | 1981 | Renamed to Arizona Pacific Airlines |
| Omniflight Helicopters | Texas | | | | Addison | 1962 | 2011 | Acquired by Air Methods |
| ONAT (Orvis Nelson Air Transport Company) | California | OE | | | Oakland | 1946 | 1946 | Renamed to Transocean Air Lines |
| Oneida County Aviation | New York | | | | Oneida County | 1975 | 1976 | Renamed to Empire Airlines |
| OneJet | Pennsylvania | J1 | | | Pittsburgh | 2015 | 2018 | Established as PrimAir |
| ONG Airlines | Illinois | | | | Chicago Meigs Field | 2015 | 2018 | Founded by William Armitage Ong. Established as PrimAir |
| Orange Air | Florida | U3 | ORN | ORANGE JET | Orlando Sanford | 2011 | 2017 | Charter operator |
| Orion Air | North Carolina | HS | TAG | TAGGE | Raleigh–Durham | 1980 | 1989 | Sold to Ryan International |
| Orion Airways | Missouri | | | | St. Louis Lambert | 1971 | 1971 | Third-level services |
| Orlando Airlines | Florida | | | | Orlando | 1943 | 1947 | Renamed to Florida Airways |
| Oscar Winchell Air Service | Alaska | | | | Anchorage | 1931 | 1932 | Founded by Oscar Winchell |
| Otis Spunkmeyer Air | California | | | | Oakland | 1990 | 1999 | Established as Sentimental Journeys Aviation. Operated DC-3 |
| Otter Air | Washington | | | | Seattle Lake Union Seaplane Base | 1985 | 1986 | Scheduled and charter seaplane services. Acquired by Kenmore Air |
| Overland Airways | Oklahoma | | | | Alameda | 1929 | 1932 | |
| Overseas International Distributors | California | | | | Van Nuys | 1978 | 1979 | Renamed to Ginny Aviation. Operated Boeing 720 |
| Overseas National Airways | New York | OV | OV | Liberty | New York Kennedy | 1946 | 1978 | The original version. |
| Overseas National Airways (second version) | New York | OV | ONA | ONAIR | New York Kennedy | 1982 | 1983 | dba for United Air Carriers, operated as "National Airlines" 1983–1985 |
| Owensboro Aviation | Kentucky | | | | Owensboro–Daviess | 1964 | 1974 | Founded by L.S. Cox. Renamed to Air Kentucky |
| Oxnard Sky Freight | California | | | | Oxnard | 1946 | 1951 | Founded 24 November 1946 as partnership in Ventura County by Voyle Banks, Ralph Hicks & Melvin Hicks |
| Ozark Air Lines | Missouri | OZ | OZA | OZARK | St Louis Lambert International Airport | 1950 | 1986 | To Trans World Airlines |
| Ozark Air Lines (1998) | Missouri | | OZR | | Oklahoma Will Rogers | 1998 | 2001 | To Great Plains Airlines |
| P ||||||||||
| P & M Flying Services | Maine | | PAZ | PAPA MIKE | Presque Isle | 1965 | 1968 | Founded by John C. Philbrick. Renamed to Aroostook Airways |
| P & N Flight and Charter | Indiana | | | | Marion | 1995 | 1996 | Passenger and cargo charters |
| PAC Air | Massachusetts | | PCR | PACAIR | Provincetown | 1989 | 1989 | Owned by Arthur Pearson. Sold to San Juan Airlines |
| Pace Airlines | North Carolina | Y5 | PCE | PACE | Winston-Salem Smith Reynolds | 1996 | 2002 | To Hooters Air |
| Pacific Air Charter | California | | PRC | PACIFIC CHARTER | San Diego | 1994 | 1996 | Acquired by Airnet Express |
| Pacific Air Express | Hawaii | | PCF | PACIFIC EXPRESS | Honolulu | 1983 | 1986 | |
| Pacific Air Freight | Washington | | | | Seattle–Tacoma | 1951 | 1968 | Merged with Airborne of California to form Airbourne Freight Company |
| Pacific Air Lines | California | PC | PC | PACIFIC | San Francisco | 1946 | 1968 | Renamed 1958 from Southwest Airways, merged w/ Bonanza and West Coast to form Air West later renamed Hughes Airwest |
| Pacific Air Transport | California | | | | | 1926 | 1928 | Merged into Boeing Air Transport, but remained a separate division |
| Pacific Airways | Alaska | 3F | | | Ketchikan | 2000 | 2020 | Operated DHC Beaver floatplane |
| Pacific Alaska Airlines | Alaska | AW | PAK | PACIFIC ALASKA | Fairbanks | 1972 | 1986 | Operated de Havilland Heron, DC-3, DC-6, Fairchild Packet, B-25 Mitchell |
| Pacific Alaska Airways | Alaska | | | | Juneau | 1932 | 1941 | Merged into Pan American World Airways |
| Pacific American Airlines | California | | | | Burbank Hollywood | 1975 | 1978 | uncertificated carrier follow on from Mercer Airlines |
| Pacific Cal Air | California | AX | PCC | | Oakland | 1979 | 1984 | |
| Pacific Cargo | California | | | | Los Angeles | 1985 | 1985 | Operated DC-8-50F |
| Pacific Coast Airlines | | | | SONIC | Santa Barbara | 1981 | 1985 | Established as Apollo Airways |
| Pacific Corporation | Delaware | | | | | 1950 | 1979 | Holding company Used by CIA to control aviation front organizations |
| Pacific East Airlines | California | 6P | PCE | | Los Angeles | 1983 | 1984 | |
| Pacific Express | California | VB | WCA | | Chico | 1982 | 1984 | |
| Pacific Inter Air | Florida | QT | PIA | | Miami | 1985 | 1987 | Established as Pacific Interstate. Renamed to Bahamas Express |
| Pacific International Airlines | Arizona | | PIN | | Tucson | 1995 | 1996 | Established as Sportsflight Airways |
| Pacific Interstate Airlines | Nevada | | | | Las Vegas McCarran | 1984 | 1985 | Renamed Pacific Inter Air |
| Pacific Island Aviation | Northern Mariana Islands | 9J | PSA | PACIFIC ISLE | Saipan | 1988 | 2005 | |
| Pacific Marine Airways | California | | | | Avalon | 1922 | 1928 | Operated two Curtiss HS |
| Pacific National Airways | California | | | | Burbank | 1980 | 1981 | Established as Air Tours |
| Pacific Northern Airlines | Alaska | PN | | | Anchorage | 1947 | 1967 | Established as Woodley Airways by Art Woodley in 1932. Renamed to Pacific Northern Airway. Merged into Western Airlines |
| Pacific Ocean Airlines | Hawaii | | | | Honolulu | 1946 | 1948 | |
| Pacific Overseas Airlines | California | | | | Ontario | 1946 | 1947 | Established as Industrial Air Transport. Operated C-54 Skymaster. Daily flight to Tokyo |
| Pacific Seaboard Air Lines | California | | | | Monterey | 1933 | 1935 | Renamed to Chicago and Southern Air Lines. Operated Bellanca CH-300 |
| Pacific Skyway | California | | | | | 2000 | 2003 | |
| Pacific Southwest Airlines | California | PS | PSX | SMILEY | Los Angeles | 1949 | 1988 | To US Airways |
| Pacific Western Airways | Utah | | | | Salt Lake City | 1968 | 1969 | |
| Pacific Wings | Arizona | LW | NMI | TSUNAMI | Albuquerque Sunport | 1974 | 2015 | See also New Mexico Airlines, Georgia Skies, TennesseeSkies, and KentuckySkies |
| Paklook Air | Alaska | | | | Fairbanks | 2003 | 2003 | Founded by Howard Holman and Terry Cratty. Renamed to Servant Air. Operated Cessna 207 |
| Palm Springs Airlines | California | | | | Palm Springs | 1936 | 1937 | |
| Pan Alaska Airways | Alaska | | | | Fairbanks | 1970 | 1973 | Renamed to Pacific Alaska Airlines. Acquired by Empire Airlines in 1989 |
| Pan Am Air Bridge | Florida | | | | Miami Seaplane Base | 1996 | 1999 | |
| Pan American World Airways | New York | PA | PAA | CLIPPER | New York Kennedy | 1927 | 1991 | Went bankrupt |
| Pan Am Cargo | New York | PA | PAA | CLIPPER | New York Kennedy | 1963 | 1983 | Subsidiary of Pan American World Airways |
| Pan Am Express | New York | RZ | PXX | PAN AM | Miami | 1981 | 1991 | A flight connection code sharing service operated by several air carriers. See also Ransome Airlines |
| Pan Am Shuttle | New York | | | | | 1986 | 1991 | To Delta Shuttle |
| Pan American Airways (1996–1998) | Florida | PN | PAA | CLIPPER | Miami | 1996 | 1998 | Merged with Carnival Air Lines |
| Pan American Airways (1998–2004) | New Hampshire | PA | PAA | CLIPPER | Portsmouth | 1998 | 2004 | To Boston-Maine Airways |
| Pan American-Grace Airways | Florida | PG | PG | | | 1929 | 1969 | To Braniff International Airways |
| Panagra Airways | Florida | 7E | PGI | PANAGRA | Fort Lauderdale-Hollywood | 1996 | 1999 | |
| Panama Airways | Florida | | | | Panama City–Bay County | 1990 | 1991 | |
| Panhandle Airways | Florida | | | | | 1976 | 1978 | Operated Beech 18, DC-3 |
| Paradise Airlines | California | | | | Oakland | 1962 | 1964 | intrastate airline that operated L-049. One of its two founders later founded Holiday Airlines |
| Paradise Airways | Virginia | | | | Manassas | 1995 | 1997 | Charter carrier. Renamed to Prestige Airlines |
| Paradise Island Airlines | Florida | BK | PDI | PARADISE ISLAND | Miami | 1989 | 1999 | |
| Paragon Air | Hawaii | | | | Honolulu | 1985 | 2006 | Charter operator |
| Paramount Airlines | California | | | | Burbank | 1961 | 1962 | Supplemental air carrier. Originally Paul Mantz Air Services. CAB refused to certificate it in 1962 due to combine activity. |
| Parks Air Lines | Illinois | | | | Parks Metropolitan Airport | 1950 | 1950 | Founded as Parks Air Transport in 1944. Acquired by Ozark Air Lines |
| Passaat Airlines | Florida | | | | Miami | 1965 | 1967 | Charter operator |
| Patriot Air | Texas | | | | Dallas Love Field | 2001 | 2002 | |
| Patriot Airlines | California | P7 | PAA | PATRIOTAIR | San Jose | 1991 | 1994 | |
| Paul Mantz Air Services | California | | | | Burbank | 1947 | 1961 | Renamed to Paramount Airlines |
| Peak Air | Colorado | | | | Aspen | 1995 | 1995 | Renamed to Aspen Mountain Air |
| Pearson Aircraft | Washington | YE | | | Port Angeles | 1972 | 1981 | Founded by Earl Pearson. Acquired by San Juan Airlines |
| Pearson-Alaska Airlines | Alaska | | | | Anchorage | 1948 | 1956 | Founded by Eric Pearson. Renamed to World Wide Airlines. Operated DC-4, C-46, L-749, L-1049 |
| Peck & Rice Airways | Alaska | | | | Bethel | 1930 | 1939 | Founded by John Peck and Wyman Rice. Operated Travel Air 6000B |
| Pegaso Air | California | | | | Los Angeles | 1985 | 1986 | |
| Pegasus Air | Washington | | | | Bremerton | 1985 | 1986 | Operated Cessna 172 |
| Peninsula Airways | California | | | | San Carlos | 1973 | 1973 | |
| Peninsular Air Transport | Florida | | | | Miami | 1946 | 1957 | Irregular air carrier shut by CAB in 1957 for combine activities |
| Pennsylvania Air Lines | Pennsylvania | | | | Bettis Field | 1930 | 1936 | Merged with Central Airlines to form Pennsylvania Central Airlines |
| Pennsylvania Airlines | Pennsylvania | | | | Harrisburg | 1980 | 1985 | Acquired by USAir |
| Pennsylvania Central Airlines | Pennsylvania | | | | Allegheny County | 1936 | 1948 | Formed by the merger of Central Airlines and Pennsylvania Airlines. Operated DC-3A. To Capital Airlines |
| Pennsylvania Commuter Airlines | Pennsylvania | AL | | | Harrisburg | 1970 | 1980 | Established as Harrisburg Commuter. Became an Allegheny Commuter and renamed to Pennsylvania Airlines. |
| Penobscot Airways | Maine | | | | Millinocket Seaplane Base | 1949 | 1955 | Founded by Arthur Harjula. Renamed to Stonington Flying Service |
| People Express Airlines (1980s) | New Jersey | PE | PEX | PEOPLE EXPRESS | Newark Liberty | 1981 | 1987 | Merged into Continental Airlines |
| People Express Airlines (2010s) | Virginia | V2 | RBY | RUBY | Newport News/Williamsburg | 2014 | 2014 | |
| Permian Airways | Texas | | | | Midland | 1979 | 1982 | Founded by John Andrews and David Glover |
| Pet Airways | Florida | | SUB | SUB AIR | | 2009 | 2013 | |
| PHH Air | Kansas | | | | Wichita | 1986 | 1989 | Founded by Jack P DeBoer and Ron Ryan. Established as Ryan Aviation. Renamed to Ryan International Airlines |
| Philadelphia Rapid Transit | Pennsylvania | | | | Philadelphia | 1926 | 1926 | Operated Fokker F.VII |
| Phoenix Air | Georgia | | | | Cartersville | 2002 | 2003 | |
| Phoenix Airways | Georgia | | | | DeKalb–Peachtree | 1980 | 1981 | |
| Pickwick Airways | California | | | | Los Angeles | 1929 | 1930 | Operated Bach Air Yacht |
| Piedmont Airlines (1948–1989) | North Carolina | PI | PAI | PIEDMONT | Charlotte Douglas | 1948 | 1989 | To US Airways |
| Pilgrim Airlines | Connecticut | PM | PMT | PILGRIM | Groton-New London | 1960 | 1986 | Acquired by Business Express Airlines |
| Pine State Airlines | Maine | PW | PXX | | Frenchville | 1990 | 1999 | Operated Cessna 402C |
| Pinehurst Airlines | Georgia | MQ | | | Whispering Pines | 1973 | 1982 | Operated YS-11, C-47A. Went into bankruptcy due to PATCO |
| Pinnacle Airlines | Michigan | 9E | FLG | FLAGSHIP | Detroit Metro | 2002 | 2013 | Establishes as Express Airlines I. Renamed to Endeavor Air |
| Pioneer Air Lines | Texas | | | | Houston-Hobby | 1946 | 1955 | Merged into Continental Airlines |
| Pioneer Airlines | Colorado | JB | PIO | PIONEER | Denver | 1976 | 1986 | Establishes as Pioneer Airways. Operated Beech 99 |
| Pioneer Airways | South Dakota | | | | | 1927 | 1928 | Founded by Oscar Winclell. Renamed to Rapid City Airlines. Operated Curtiss Jenny |
| Pioneer Airways | Alaska | | | | Ketchikan | 1931 | 1931 | Founded by Vern C. Gorst, Roy F. Jones, C.R. Wright Jones. Renamed to Ketchikan Airways. Operated Curtiss Jenny |
| Pitcairn Aviation | New York | | | | Floyd Bennett Field | 1927 | 1930 | Founded by Harold J. Pitcairn. Renamed to Eastern Air Transport |
| Pittsburgh Airways | Pennsylvania | | | | Allegheny County | 1929 | 1930 | Founded by James Condon, Ted Taney. Subsidiary of New York & Western Airlines |
| Planet Airways | Florida | | PLZ | PLANET | Orlando | 1995 | 2006 | Began as Airship Airways |
| Platinum Airlines | Florida | P2 | PLS | | Miami | 1998 | 2006 | |
| Pocono Airlines | Pennsylvania | 4P | POC | POCONO | Wilkes-Barre/Scranton | 1965 | 1990 | Began flying as an Allegheny Commuter, switched to TWA Express in 1989. |
| Polar Airways | Alaska | PE | | | Anchorage | 1968 | 1979 | Operated Aero Commander |
| Pollack Flying Service | Alaska | | | | Fairbanks | 1933 | 1942 | Founded by Frank Pollack. Sold to Alaska Star Airlines |
| Pompano Airways | Florida | MG | | | Fort Lauderdale Executive | 1983 | 1984 | Subcontract carrier for Air Florida Commuter |
| Pomona Valley Aviation | California | | | | Brackett Field | 1968 | 1975 | Renamed to Inland Empire Airlines. Operated Piper Navajo, Swearingen Metroliner |
| Port Angeles Air Transport | Washington | | | | Port Angeles | 1931 | 1931 | Operated Stinson Detroiter |
| Potomac Air | Texas | BK | PDC | DISTRICT | Washington National | 2001 | 2001 | Renamed to Midatlantic Airways. Operated DHC-8 |
| Precision Airlines | New Hampshire | RP | PRE | PRECISION | Manchester–Boston | 1972 | 1994 | Was an Eastern Express carrier. Acquired by Northeast Express in 1989. |
| Premier Executive Transport Services | Massachusetts | | | | | | | Alleged to be a front organization for the Central Intelligence Agency |
| President Airlines | California | | | | Burbank | 1960 | 1962 | Operated DC-4, DC-6, DC-7 |
| Presidential Air | California | | PRD | PRESIDENTIAL | Long Beach | 1993 | 1996 | Operated Airbus A300 |
| Presidential Airways (scheduled) | Virginia | XV | | WASHINGTON EAGLE | Washington Dulles | 1985 | 1989 | |
| Presidential Express | Virginia | CJ | CJC | COLGAN | Manassas | 1986 | 1989 | Began as Colgan Airways |
| Prestige Airways | New York | OJ | PAI | | New York Kennedy | 1995 | 1997 | Established as Paradise Airways in 1990. Operated 727-200 |
| Pride Air | Louisiana | NI | | | New Orleans | 1985 | 1985 | Went into bankruptcy |
| PrimAir | Pennsylvania | | | | Pittsburgh | 2009 | 2014 | Rebranded OneJet |
| Primaris Airlines | Nevada | FE | WCP | WHITECAP | Las Vegas McCarran | 2002 | 2009 | |
| Prime Air | Pennsylvania | | | | Clarksville | 1986 | 1987 | Operated Piper |
| Prime Air | Illinois | | | | Murphysboro | 1988 | 1989 | |
| Prinair | Puerto Rico | PQ | | COLORBIRD, PRU | Ponce | 1966 | 1985 | Established as Aerolíneas de Ponce (Ponce Airlines) |
| Princeton Air Link | New Jersey | IV | PCN | PRINCETON | Princeton | 1986 | 1988 | Operated BN Islander. Went into bankruptcy |
| Princeton Airways | New Jersey | | | | Princeton | 1978 | 1979 | Operated BN Islander, GAF Nomad |
| Princeton Aviation Corporation | New Jersey | | | | Princeton | 1950 | 1979 | Founded by Webster B. Todd and Lawrence Tokash. Participated in the Metro Air Service with A.A. in 1965 |
| Princeville Airways | Hawaii | | | | Honolulu | 1980 | 1987 | Renamed to Aloha Island Air. Operated Twin Otter |
| Private Jet Expeditions | Georgia | 5J | PJE | PEE JAY | Atlanta | 1989 | 1995 | |
| Pro Air | Florida | | | | Miami | 1981 | 1988 | |
| Pro Air | Washington | P9 | PRH | PROHAWK | Detroit Young | 1997 | 2000 | |
| Profit Express Airlines | New York | | | | New York Kennedy | 1945 | 1985 | Operated Convair 880 |
| Pronto Aviation Services | Texas | | | | El Paso | 1982 | 1983 | Renamed to Atorie Air |
| Provincetown-Boston Airlines | Massachusetts | PT | PBA | | Provincetown | 1949 | 1989 | |
| Puertorriqueña de Aviación | Puerto Rico | | | | | 1936 | 1941 | Also known as Aerovías Nacionales de Puerto Rico |
| Puget Sound Airlines | Washington | | | | Bellingham | 1969 | 1970 | Formed by the merger of six local airlines. To San Juan Airlines. Operated Beech Expeditor, Cherokee Six |
| Purdue Aeronautics Corporation | Indiana | | | | Lafayette, IN | 1949 | 1950 | CAB-certificated scheduled service on Chicago-Lafayette, owned by Purdue University |
| Purdue Aeronautics Corporation | Indiana | | | | Lafayette, IN | 1953 | 1968 | Charter operator run by Purdue University |
| Purdue Airlines | Indiana | | | | Lafayette, IN | 1968 | 1971 | Charter operator owned by Stephens Inc. with Purdue University participation |