# 2023 Mutua Madrid Open – Men's singles

Defending champion Carlos Alcaraz defeated Jan-Lennard Struff in the final, 6–4, 3–6, 6–3 to win the men's singles tennis title at the 2023 Madrid Open. It was his fourth Masters 1000 title. Struff was the first lucky loser to reach a Masters final.
This was the first edition in the tournament's 21-year history to not feature Roger Federer, Rafael Nadal, or Novak Djokovic (collectively known as the Big Three) in the main draw. They won 11 of the preceding 16 editions of the Madrid Open, reaching 13 finals in total.
Zhang Zhizhen was the first Chinese to reach the singles quarterfinals of a Masters event. Aslan Karatsev was only the second qualifier to reach the Madrid Open semifinals, after Fabrice Santoro in 2002. The semifinal encounter between Karatsev and Struff was a rematch of their meeting in the qualifying rounds of the tournament, which Karatsev had won; Struff won their semifinal rematch.

## Seeds

All seeds received a bye into the second round.
    01. Carlos Alcaraz (champion)
    02. Daniil Medvedev (fourth round)
    03. Casper Ruud (second round)
    04. Stefanos Tsitsipas (quarterfinals)
    05. Andrey Rublev (fourth round)
    06. Holger Rune (third round)
    07. Félix Auger-Aliassime (second round)
    08. Taylor Fritz (fourth round)
    09. Frances Tiafoe (third round)
    10. Karen Khachanov (quarterfinals)
    11. Cameron Norrie (third round)
    12. Hubert Hurkacz (third round)
    13. Alexander Zverev (fourth round)
    14. Tommy Paul (second round)
    15. Lorenzo Musetti (second round)
    16. Alex de Minaur (third round)
    17. Borna Ćorić (semifinals)
    18. Pablo Carreño Busta (withdrew)
    19. Dan Evans (second round)
    20. Roberto Bautista Agut (third round)
    21. Denis Shapovalov (second round)
    22. Sebastian Korda (second round)
    23. Botic van de Zandschulp (second round)
    24. Francisco Cerúndolo (second round)
    25. Sebastián Báez (third round)
    26. Grigor Dimitrov (third round)
    27. Miomir Kecmanović (second round)
    28. Yoshihito Nishioka (third round)
    29. Alejandro Davidovich Fokina (fourth round)
    30. Tallon Griekspoor (second round, retired)
    31. Jiří Lehečka (second round)
    32. Ben Shelton (second round)
Click on the seed number of a player to go to their draw section.

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final | Final | Final |
| 1 | Carlos Alcaraz | 6 | 7 | | | | | | | | | | | |
| 10 | Karen Khachanov | 4 | 5 | | | | | | | | | | | |
| 10 | Karen Khachanov | 4 | 5 | | 1 | Carlos Alcaraz | 6 | 6 | | | | | | |
| | | | | | 17 | Borna Ćorić | 4 | 3 | | | | | | |
| LL | Daniel Altmaier | 3 | 3 | | 17 | Borna Ćorić | 4 | 3 | | | | | | |
| 17 | Borna Ćorić | 6 | 6 | | | | | | | | | | | |
| 17 | Borna Ćorić | 6 | 6 | | | | | | | 1 | Carlos Alcaraz | 6 | 3 | 6 |
| | | | | | | | | | | LL | Jan-Lennard Struff | 4 | 6 | 3 |
| LL | Jan-Lennard Struff | 7$^7$ | 5 | 6 | | | | | | | | | | | LL | Jan-Lennard Struff | 4 | 6 | 3 |
| 4 | Stefanos Tsitsipas | 6$^5$ | 7 | 3 | | | | | | | | | | |
| 4 | Stefanos Tsitsipas | 6$^5$ | 7 | 3 | LL | Jan-Lennard Struff | 4 | 6 | 6 | | | | | |
| | | | | | Q | Aslan Karatsev | 6 | 3 | 4 | | | | | |
| | Zhang Zhizhen | 6$^3$ | 4 | | Q | Aslan Karatsev | 6 | 3 | 4 | | | | | |
| Q | Aslan Karatsev | 7$^7$ | 6 | | | | | | | | | | | |

### Top half
#### Section 1

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Third round | Third round | Third round | Third round | Fourth round | Fourth round | Fourth round | Fourth round |
| | | | | | 1 | C Alcaraz | 2 | 6 | 6 | | | | | | | | |
| | E Ruusuvuori | 7$^8$ | 7$^7$ | | | E Ruusuvuori | 6 | 4 | 2 | | | | | | | | |
| | U Humbert | 6$^6$ | 6$^4$ | | | | | | | 1 | C Alcaraz | 6 | 7 | | | | |
| WC | E Nava | 0 | 7 | 3 | | | | | | 26 | G Dimitrov | 2 | 5 | | | | |
| | G Barrère | 6 | 5 | 6 | | G Barrère | 6$^6$ | 6$^2$ | | | | | | | | | |
| | | | | | 26 | G Dimitrov | 7$^8$ | 7$^7$ | | | | | | | | | |
| | | | | | | | | | | | | | | 1 | C Alcaraz | 6 | 6 |
| | | | | | | | | | | | | | | 13 | A Zverev | 1 | 2 |
| | | | | | 22 | S Korda | 6$^5$ | 6$^7$ | | | | | | | | | |
| | D Schwartzman | 5 | 4 | | Q | H Grenier | 7$^7$ | 7$^9$ | | | | | | | | | |
| Q | H Grenier | 7 | 6 | | | | | | | Q | H Grenier | 1 | 0 | | | | |
| | R Carballés Baena | 6 | 6 | | | | | | | 13 | A Zverev | 6 | 6 | | | | |
| | D Goffin | 4 | 4 | | | R Carballés Baena | 7$^8$ | 5 | 0 | | | | | | | | |
| | | | | | 13 | A Zverev | 6$^6$ | 7 | 6 | | | | | | | | |

#### Section 2

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Third round | Third round | Third round | Third round | Third round | Fourth round | Fourth round | Fourth round | Fourth round |
| | | | | | 10 | K Khachanov | 6 | 3 | 6 | | | | | | | | | |
| | T Monteiro | 7$^{11}$ | 4 | 6 | | T Monteiro | 3 | 6 | 3 | | | | | | | | | |
| Q | B Gojo | 6$^9$ | 6 | 3 | | | | | | 10 | K Khachanov | 7 | 4 | 6 | | | | |
| | A Popyrin | 6 | 4 | 4 | | | | | | 20 | R Bautista Agut | 5 | 6 | 3 | | | | |
| | Q Halys | 4 | 6 | 6 | | Q Halys | 6 | 6$^5$ | 3 | | | | | | | | | |
| | | | | | 20 | R Bautista Agut | 4 | 7$^7$ | 6 | | | | | | | | | |
| | | | | | | | | | | | | | | | 10 | K Khachanov | 7$^{10}$ | 6 |
| | | | | | | | | | | | | | | | 5 | A Rublev | 6$^8$ | 4 |
| | | | | | 28 | Y Nishioka | 5 | 6 | 6 | | | | | | | | | |
| | Y Wu | 2 | 4 | | | A Molčan | 7 | 4 | 4 | | | | | | | | | |
| | A Molčan | 6 | 6 | | | | | | | 28 | Y Nishioka | 2 | 5 | | | | | |
| | M Cressy | 7$^7$ | 3 | 6$^4$ | | | | | | 5 | A Rublev | 6 | 7 | | | | | |
| | S Wawrinka | 6$^3$ | 6 | 7$^7$ | | S Wawrinka | 5 | 4 | | | | | | | | | | |
| | | | | | 5 | A Rublev | 7 | 6 | | | | | | | | | | |

#### Section 3

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Third round | Third round | Third round | Third round | Third round | Fourth round | Fourth round | Fourth round | Fourth round |
| | | | | | 3 | C Ruud | 3 | 4 | | | | | | | | | |
| Q | B Paire | 1 | 6 | 6$^6$ | Q | M Arnaldi | 6 | 6 | | | | | | | | | |
| Q | M Arnaldi | 6 | 3 | 7$^8$ | | | | | Q | M Arnaldi | 6 | 3 | 1 | | | | |
| | T Kokkinakis | 6$^7$ | 6$^3$ | | | | | | | J Munar | 3 | 6 | 6 | | | | |
| | J Munar | 7$^9$ | 7$^7$ | | | J Munar | 7$^7$ | 0 | | | | | | | | | |
| | | | | | 30 | T Griekspoor | 6$^3$ | 0$^r$ | | | | | | | | | |
| | | | | | | | | | | | | | | | J Munar | 3 | 0 |
| | | | | | | | | | | | | | | LL | D Altmaier | 6 | 6 |
| | | | | | LL | D Altmaier | 6 | 7 | | | | | | | | | |
| LL | P Kotov | 3 | 6 | 4 | | O Otte | 4 | 5 | | | | | | | | | |
| | O Otte | 6 | 4 | 6 | | | | | LL | D Altmaier | 7$^7$ | 6 | | | | | |
| | JP Varillas | 4 | 6 | 3 | | | | | Q | Y Hanfmann | 6$^3$ | 3 | | | | | |
| Q | Y Hanfmann | 6 | 3 | 6 | Q | Y Hanfmann | 6 | 7$^7$ | | | | | | | | | |
| | | | | | 15 | L Musetti | 4 | 6$^3$ | | | | | | | | | |

#### Section 4

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Third round | Third round | Third round | Third round | Third round | Fourth round | Fourth round | Fourth round | Fourth round | Fourth round |
| | | | | | 12 | H Hurkacz | 6$^9$ | 6 | 7 | | | | | | | | | | |
| WC | M Landaluce | 2 | 1 | | | R Gasquet | 7$^{11}$ | 4 | 5 | | | | | | | | | | |
| | R Gasquet | 6 | 6 | | | | | | | 12 | H Hurkacz | 6$^3$ | 3 | | | | | | |
| PR | J Chardy | 3 | 4 | | | | | | | 17 | B Ćorić | 7$^7$ | 6 | | | | | | |
| WC | H Gaston | 6 | 6 | | WC | H Gaston | 3 | 3 | | | | | | | | | | | |
| | | | | | 17 | B Ćorić | 6 | 6 | | | | | | | | | | | |
| | | | | | | | | | | | | | | | 17 | B Ćorić | 6$^5$ | 6 | 7$^7$ |
| | | | | | | | | | | | | | | | 29 | A Davidovich Fokina | 7$^7$ | 3 | 6$^5$ |
| | | | | | 29 | A Davidovich Fokina | 6 | 6 | | | | | | | | | | | |
| | A Ramos Viñolas | 4 | 7$^7$ | 6 | | A Ramos Viñolas | 3 | 4 | | | | | | | | | | | |
| | I Ivashka | 6 | 6$^3$ | 2 | | | | | | 29 | A Davidovich Fokina | 7$^7$ | 5 | 7$^7$ | | | | | |
| | A Bublik | 7$^{17}$ | 6$^4$ | 6 | | | | | | 6 | H Rune | 6$^1$ | 7 | 6$^5$ | | | | | |
| | DE Galán | 6$^{15}$ | 7$^7$ | 4 | | A Bublik | 1 | 6 | 6$^9$ | | | | | | | | | | |
| | | | | | 6 | H Rune | 6 | 4 | 7$^{11}$ | | | | | | | | | | |

### Bottom half
#### Section 5

| First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Third round | Third round | Third round | Third round | Third round | Fourth round | Fourth round | Fourth round | Fourth round | Fourth round |
| | | | | 7 | F Auger-Aliassime | 2 | 6 | 6$^5$ | | | | | | | | | | |
| | J Kubler | 3 | 3 | | D Lajović | 6 | 3 | 7$^7$ | | | | | | | | | | |
| | D Lajović | 6 | 6 | | | | | | | D Lajović | 7$^7$ | 3 | 3 | | | | | |
| | L Sonego | 3 | 1 | | | | | | LL | J-L Struff | 6$^2$ | 6 | 6 | | | | | |
| LL | J-L Struff | 6 | 6 | LL | J-L Struff | 4 | 7$^7$ | 7 | | | | | | | | | | |
| | | | | 32 | B Shelton | 6 | 6$^4$ | 5 | | | | | | | | | | |
| | | | | | | | | | | | | | | LL | J-L Struff | 7$^9$ | 6$^7$ | 6 |
| | | | | | | | | | | | | | | | P Cachin | 6$^7$ | 7$^9$ | 3 |
| | | | | 24 | F Cerúndolo | 1 | 6$^6$ | | | | | | | | | | | |
| WC | A Shelbayh | 1 | 4 | | P Cachin | 6 | 7$^8$ | | | | | | | | | | | |
| | P Cachin | 6 | 6 | | | | | | | P Cachin | 6 | 7$^7$ | | | | | | |
| | TM Etcheverry | 6 | 6 | | | | | | 9 | F Tiafoe | 1 | 6$^2$ | | | | | | |
| | A Mannarino | 4 | 0 | | TM Etcheverry | 3 | 6$^5$ | | | | | | | | | | | |
| | | | | 9 | F Tiafoe | 6 | 7$^7$ | | | | | | | | | | | |

#### Section 6

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Third round | Third round | Third round | Third round | Third round | Fourth round | Fourth round | Fourth round | Fourth round |
| | | | | | 14 | T Paul | 3 | 6$^3$ | | | | | | | | | | |
| Q | R Safiullin | 6 | 3 | 6 | Q | R Safiullin | 6 | 7$^7$ | | | | | | | | | | |
| | N Jarry | 2 | 6 | 3 | | | | | | Q | R Safiullin | 3 | 6 | 3 | | | | |
| | M McDonald | 6 | 3 | 6$^4$ | | | | | | | B Zapata Miralles | 6 | 3 | 6 | | | | |
| | B Zapata Miralles | 3 | 6 | 7$^7$ | | B Zapata Miralles | 6 | 6 | | | | | | | | | | |
| | | | | | 19 | D Evans | 3 | 2 | | | | | | | | | | |
| | | | | | | | | | | | | | | | | B Zapata Miralles | 3 | 1 |
| | | | | | | | | | | | | | | | 4 | S Tsitsipas | 6 | 6 |
| | | | | | 25 | S Báez | 3 | 6 | 6 | | | | | | | | | |
| | N Borges | 2 | 6$^7$ | | | M Giron | 6 | 3 | 4 | | | | | | | | | |
| | M Giron | 6 | 7$^9$ | | | | | | | 25 | S Báez | 5 | 6 | 3 | | | | |
| PR | K Edmund | 4 | 1 | | | | | | | 4 | S Tsitsipas | 7 | 3 | 6 | | | | |
| WC | D Thiem | 6 | 6 | | WC | D Thiem | 6 | 1 | 6$^5$ | | | | | | | | | |
| | | | | | 4 | S Tsitsipas | 3 | 6 | 7$^7$ | | | | | | | | | |

#### Section 7

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Third round | Third round | Third round | Third round | Third round | Fourth round | Fourth round | Fourth round | Fourth round | Fourth round |
| | | | | | 8 | T Fritz | 7$^{13}$ | 6 | | | | | | | | | | | |
| | C O'Connell | 6 | 6$^2$ | 6 | | C O'Connell | 6$^{11}$ | 4 | | | | | | | | | | | |
| | F Krajinović | 4 | 7$^7$ | 2 | | | | | | 8 | T Fritz | 6 | 7$^7$ | | | | | | |
| | C Garín | 7$^7$ | 6 | | | | | | | | C Garín | 1 | 6$^4$ | | | | | | |
| | M-A Hüsler | 6$^5$ | 2 | | | C Garín | 7$^7$ | 6$^5$ | 6 | | | | | | | | | | |
| | | | | | 27 | M Kecmanović | 6$^3$ | 7$^7$ | 4 | | | | | | | | | | |
| | | | | | | | | | | | | | | | 8 | T Fritz | 6 | 6$^5$ | 6$^8$ |
| | | | | | | | | | | | | | | | | Z Zhang | 3 | 7$^7$ | 7$^{10}$ |
| | | | | | 21 | D Shapovalov | 7$^7$ | 4 | 6$^1$ | | | | | | | | | | |
| Q | J Rodionov | 6$^6$ | 4 | | | Z Zhang | 6$^4$ | 6 | 7$^7$ | | | | | | | | | | |
| | Z Zhang | 7$^8$ | 6 | | | | | | | | Z Zhang | 2 | 7$^7$ | 7$^7$ | | | | | |
| | C Moutet | 3 | 3 | | | | | | | 11 | C Norrie | 6 | 6$^2$ | 6$^2$ | | | | | |
| Q | Y Watanuki | 6 | 6 | | Q | Y Watanuki | 4 | 6$^5$ | | | | | | | | | | | |
| | | | | | 11 | C Norrie | 6 | 7$^7$ | | | | | | | | | | | |

#### Section 8

| First round | First round | First round | First round | Second round | Second round | Second round | Second round | Third round | Third round | Third round | Third round | Third round | Fourth round | Fourth round | Fourth round | Fourth round |
| | | | | 16 | A de Minaur | 6 | 7$^7$ | | | | | | | | | |
| | M Fucsovics | 6$^4$ | 3 | Q | M Cecchinato | 4 | 6$^5$ | | | | | | | | | |
| Q | M Cecchinato | 7$^7$ | 6 | | | | | 16 | A de Minaur | 3 | 6 | 4 | | | | |
| Q | A Karatsev | 7$^7$ | 7 | | | | | Q | A Karatsev | 6 | 4 | 6 | | | | |
| | L Djere | 6$^5$ | 5 | Q | A Karatsev | 6 | 7 | | | | | | | | | |
| | | | | 23 | B van de Zandschulp | 2 | 5 | | | | | | | | | |
| | | | | | | | | | | | | | Q | A Karatsev | 7$^7$ | 6 |
| | | | | | | | | | | | | | 2 | D Medvedev | 6$^1$ | 4 |
| | | | | 31 | J Lehečka | 1 | 1 | | | | | | | | | |
| | JJ Wolf | 4 | 4 | Q | A Shevchenko | 6 | 6 | | | | | | | | | |
| Q | A Shevchenko | 6 | 6 | | | | | Q | A Shevchenko | 6 | 1 | 5 | | | | |
| Q | A Vavassori | 6 | 7$^9$ | | | | | 2 | D Medvedev | 4 | 6 | 7 | | | | |
| | A Murray | 2 | 6$^7$ | Q | A Vavassori | 4 | 3 | | | | | | | | | |
| | | | | 2 | D Medvedev | 6 | 6 | | | | | | | | | |

## Seeded players

The following are the seeded players. Seedings are based on ATP rankings as of April 24, 2023. Rankings and points before are as of April 24, 2023.
Because the men's tournament is being expanded to two weeks this year, players are defending points from the 2022 Madrid Open, as well as tournaments that took place during the week of April 25, 2022 (Estoril and Munich). Points from the 2022 Madrid Open are listed first in the "Points defending" column.
| Seed | Rank | Player | Points before | Points defending | Points earned | Points after | Status |
| 1 | 2 | Carlos Alcaraz | 6,770 | 1,000 | 1,000 | 6,770 | Champion, defeated Jan-Lennard Struff [LL] |
| 2 | 3 | Daniil Medvedev | 5,240 | 0 | 90 | 5,330 | Fourth round lost to Aslan Karatsev [Q] |
| 3 | 4 | Casper Ruud | 5,210 | 10+45 | 10+0 | 5,165 | Second round lost to Matteo Arnaldi [Q] |
| 4 | 5 | Stefanos Tsitsipas | 5,195 | 360 | 180 | 5,015 | Quarterfinals lost to Jan-Lennard Struff [LL] |
| 5 | 6 | Andrey Rublev | 4,280 | 180 | 90 | 4,190 | Fourth round lost to Karen Khachanov [10] |
| 6 | 7 | Holger Rune | 4,070 | 250$^†$ | 45 | 3,865 | Third round lost to Alejandro Davidovich Fokina [29] |
| 7 | 9 | Félix Auger-Aliassime | 3,405 | 180 | 10 | 3,235 | Second round lost to Dušan Lajović |
| 8 | 10 | Taylor Fritz | 3,290 | 0 | 90 | 3,380 | Fourth round lost to Zhang Zhizhen |
| 9 | 11 | Frances Tiafoe | 2,870 | 10+150 | 45+0 | 2,755 | Third round lost to Pedro Cachin |
| 10 | 12 | Karen Khachanov | 2,855 | 10 | 180 | 3,025 | Quarterfinals lost to Carlos Alcaraz [1] |
| 11 | 13 | Cameron Norrie | 2,725 | 90 | 45 | 2,680 | Third round lost to Zhang Zhizhen |
| 12 | 15 | Hubert Hurkacz | 2,660 | 180 | 45 | 2,525 | Third round lost to Borna Ćorić [17] |
| 13 | 16 | Alexander Zverev | 2,140 | 600 | 90 | 1,630 | Fourth round lost to Carlos Alcaraz [1] |
| 14 | 17 | Tommy Paul | 2,070 | 10+0$^§$ | 10+32$^§$ | 2,102 | Second round lost to Roman Safiullin |
| 15 | 18 | Lorenzo Musetti | 2,065 | 115 | 10 | 1,960 | Second round lost to Yannick Hanfmann [Q] |
| 16 | 19 | Alex de Minaur | 1,995 | 45 | 45 | 1,995 | Third round lost to Aslan Karatsev [Q] |
| 17 | 20 | Borna Ćorić | 1,890 | 10 | 360 | 2,240 | Semifinals lost to Carlos Alcaraz [1] |
| 18 | 22 | Pablo Carreño Busta | 1,795 | 10 | 0 | 1,785 | Withdrew due to elbow injury |
| 19 | 24 | Dan Evans | 1,560 | 90 | 10 | 1,480 | Second round lost to Bernabé Zapata Miralles |
| 20 | 25 | Roberto Bautista Agut | 1,475 | 45 | 45 | 1,475 | Third round lost to Karen Khachanov [10] |
| 21 | 27 | Denis Shapovalov | 1,425 | 45 | 10 | 1,390 | Second round lost to Zhang Zhizhen |
| 22 | 28 | Sebastian Korda | 1,390 | 45+90 | 10+0 | 1,265 | Second round lost to Hugo Grenier [Q] |
| 23 | 29 | Botic van de Zandschulp | 1,390 | 45+150 | 10+45 | 1,250 | Second round lost to Aslan Karatsev [Q] |
| 24 | 30 | Francisco Cerúndolo | 1,235 | (45)$^‡$ | 10 | 1,200 | Second round lost to Pedro Cachin |
| 25 | 31 | Sebastián Báez | 1,190 | 250$^†$ | 45 | 985 | Third round lost to Stefanos Tsitsipas [4] |
| 26 | 32 | Grigor Dimitrov | 1,170 | 90 | 45 | 1,125 | Third round lost to Carlos Alcaraz [1] |
| 27 | 33 | Miomir Kecmanović | 1,170 | 45+90 | 10+10 | 1,055 | Second round lost to Cristian Garín |
| 28 | 34 | Yoshihito Nishioka | 1,138 | 12$^†$ | 45 | 1,171 | Third round lost to Andrey Rublev [5] |
| 29 | 35 | Alejandro Davidovich Fokina | 1,095 | 45+45 | 90+20 | 1,115 | Fourth round lost to Borna Ćorić [17] |
| 30 | 36 | Tallon Griekspoor | 1,094 | (13)$^‡$ | 10 | 1,091 | Second round retired against Jaume Munar |
| 31 | 37 | Jiří Lehečka | 1,046 | 60+12$^†$ | 10+8 | 992 | Second round lost to Alexander Shevchenko [Q] |
| 32 | 38 | Ben Shelton | 1,042 | (7)$^‡$+(10)$^§$ | 10+32 | 1067 | Second round lost to Jan-Lennard Struff [LL] |
† The player did not qualify for the main draw in 2022, but is defending points from Estoril, Munich, or Mauthausen (ATP Challenger). ‡ The player did not qualify for the main draw in 2022. Points for his 19th best result will be deducted instead. § The player entered an ATP Challenger Tour event in the second week of the Madrid tournament and points from that second tournament replaced his 19th (or 18th) best result.

### Withdrawn players

The following players would have been seeded, but withdrew before the tournament began.
| Rank | Player | Points before | Points dropped | Points after | Withdrawal reason |
| 1 | Novak Djokovic | 7,135 | 360 | 6,775 | Elbow injury |
| 8 | Jannik Sinner | 3,615 | 90 | 3,525 | Sickness |
| 14 | Rafael Nadal | 2,715 | 180 | 2,535 | Left hip injury |
| 21 | Matteo Berrettini | 1,832 | 0 | 1,832 | Abdominal injury |
| 23 | Marin Čilić | 1,645 | 45 | 1,600 | Knee injury |
| 26 | Nick Kyrgios | 1,465 | 0 | 1,465 | Left knee injury |

## Other entry information
### Wildcards

* Hugo Gaston
* Martín Landaluce
* Emilio Nava
* Abedallah Shelbayh
* Dominic Thiem

### Protected ranking

* Jérémy Chardy
* Kyle Edmund

### Withdrawals

* Matteo Berrettini → replaced by Juan Pablo Varillas
* Benjamin Bonzi → replaced by Ilya Ivashka
* Jenson Brooksby → replaced by Filip Krajinović
* Pablo Carreño Busta → replaced by Daniel Altmaier
* Marin Čilić → replaced by Christopher O'Connell
* Federico Coria → replaced by Oscar Otte
* Hugo Dellien → replaced by Thiago Monteiro
* Novak Djokovic → replaced by Zhang Zhizhen
* Jack Draper → replaced by Daniel Elahi Galán
* John Isner → replaced by Cristian Garín
* Kwon Soon-woo → replaced by Jérémy Chardy
* Nick Kyrgios → replaced by Stan Wawrinka
* Constant Lestienne → replaced by Jan-Lennard Struff
* Rafael Nadal → replaced by Quentin Halys
* Brandon Nakashima → replaced by Pavel Kotov
* Guido Pella → replaced by Roberto Carballés Baena
* Arthur Rinderknech → replaced by Ugo Humbert
* Jannik Sinner → replaced by Thanasi Kokkinakis
* Mikael Ymer → replaced by Alexei Popyrin

## Qualifying
### Seeds

* Jan-Lennard Struff (qualifying competition, lucky loser)
* Marco Cecchinato (qualified)
* Luca Van Assche (first round)
* Daniel Altmaier (qualifying competition, lucky loser)
* Alexandre Müller (first round)
* Alexander Shevchenko (qualified)
* Taro Daniel (first round)
* Matteo Arnaldi (qualified)
* Roman Safiullin (qualified)
* Pavel Kotov (qualifying competition, lucky loser)
* Borna Gojo (qualified)
* Yannick Hanfmann (qualified)
* Yosuke Watanuki (qualified)
* Otto Virtanen (first round)
* Jurij Rodionov (qualified)
* Sebastian Ofner (qualifying competition)
* Arthur Fils (qualifying competition)
* Juan Manuel Cerúndolo (qualifying competition)
* Giulio Zeppieri (qualifying competition)
* Francesco Passaro (first round)
* Hugo Grenier (qualified)
* Aslan Karatsev (qualified)
* Zsombor Piros (qualifying competition)
* Pedro Martínez (first round)

### Qualifiers

* Aslan Karatsev
* Marco Cecchinato
* Andrea Vavassori
* Jurij Rodionov
* Benoît Paire
* Alexander Shevchenko
* Hugo Grenier
* Matteo Arnaldi
* Roman Safiullin
* Yosuke Watanuki
* Borna Gojo
* Yannick Hanfmann

### Lucky losers

* Jan-Lennard Struff
* Pavel Kotov
* Daniel Altmaier

### Qualifying draw
#### First qualifier

| First round | First round | First round | First round | Qualifying competition | Qualifying competition | Qualifying competition | Qualifying competition |
| 1 | Jan-Lennard Struff | 7 | 6 | | | | |
| | Luca Nardi | 5 | 4 | | | | |
| | Luca Nardi | 5 | 4 | 1 | Jan-Lennard Struff | 4 | 2 |
| | | | | 22 | Aslan Karatsev | 6 | 6 |
| | Raúl Brancaccio | 4 | 0 | 22 | Aslan Karatsev | 6 | 6 |
| 22 | Aslan Karatsev | 6 | 6 | | | | |

#### Second qualifier

| First round | First round | First round | First round | First round | Qualifying competition | Qualifying competition | Qualifying competition | Qualifying competition |
| 2 | Marco Cecchinato | 3 | 6 | 6 | | | | |
| | Timofey Skatov | 6 | 2 | 3 | | | | |
| | Timofey Skatov | 6 | 2 | 3 | 2 | Marco Cecchinato | 7$^7$ | 6 |
| | | | | | 19 | Giulio Zeppieri | 6$^5$ | 4 |
| | Jozef Kovalík | 4 | 6 | 4 | 19 | Giulio Zeppieri | 6$^5$ | 4 |
| 19 | Giulio Zeppieri | 6 | 4 | 6 | | | | |

#### Third qualifier

| First round | First round | First round | First round | First round | Qualifying competition | Qualifying competition | Qualifying competition |
| 3 | Luca Van Assche | 3 | 6$^4$ | | | | |
| | Felipe Meligeni Alves | 6 | 7$^7$ | | | | |
| | Felipe Meligeni Alves | 6 | 7$^7$ | | Felipe Meligeni Alves | 3 | 6$^{12}$ |
| | | | | | Andrea Vavassori | 6 | 7$^{14}$ |
| | Andrea Vavassori | 6 | 6$^5$ | 6 | Andrea Vavassori | 6 | 7$^{14}$ |
| 14 | Otto Virtanen | 1 | 7$^7$ | 2 | | | |

#### Fourth qualifier

| First round | First round | First round | First round | First round | Qualifying competition | Qualifying competition | Qualifying competition | Qualifying competition |
| 4 | Daniel Altmaier | 6 | 6 | | | | | |
| PR | Attila Balázs | 1 | 1 | | | | | |
| PR | Attila Balázs | 1 | 1 | | 4 | Daniel Altmaier | 4 | 3 |
| | | | | | 15 | Jurij Rodionov | 6 | 6 |
| | Laurent Lokoli | 6 | 2 | 4 | 15 | Jurij Rodionov | 6 | 6 |
| 15 | Jurij Rodionov | 2 | 6 | 6 | | | | |

#### Fifth qualifier

| First round | First round | First round | First round | First round | Qualifying competition | Qualifying competition | Qualifying competition | Qualifying competition | Qualifying competition |
| 5 | Alexandre Müller | 4 | 6$^1$ | | | | | | |
| | Kaichi Uchida | 6 | 7$^7$ | | | | | | |
| | Kaichi Uchida | 6 | 7$^7$ | | | Kaichi Uchida | 6 | 3 | 4 |
| | | | | | WC | Benoît Paire | 3 | 6 | 6 |
| WC | Benoît Paire | 3 | 7$^7$ | 6 | WC | Benoît Paire | 3 | 6 | 6 |
| 20 | Francesco Passaro | 6 | 6$^4$ | 2 | | | | | |

#### Sixth qualifier

| First round | First round | First round | First round | Qualifying competition | Qualifying competition | Qualifying competition | Qualifying competition |
| 6 | Alexander Shevchenko | 7$^{10}$ | 7$^7$ | | | | |
| | Antoine Bellier | 6$^8$ | 6$^4$ | | | | |
| | Antoine Bellier | 6$^8$ | 6$^4$ | 6 | Alexander Shevchenko | 7$^7$ | 6 |
| | | | | 18 | Juan Manuel Cerúndolo | 6$^5$ | 4 |
| | Tseng Chun-hsin | 3 | 4 | 18 | Juan Manuel Cerúndolo | 6$^5$ | 4 |
| 18 | Juan Manuel Cerúndolo | 6 | 6 | | | | |

#### Seventh qualifier

| First round | First round | First round | First round | First round | Qualifying competition | Qualifying competition | Qualifying competition | Qualifying competition | Qualifying competition |
| 7 | Taro Daniel | 1 | 7 | 2 | | | | | |
| WC | Daniel Rincón | 6 | 5 | 6 | | | | | |
| WC | Daniel Rincón | 6 | 5 | 6 | WC | Daniel Rincón | 3 | 7$^7$ | 2 |
| | | | | | 21 | Hugo Grenier | 6 | 6$^4$ | 6 |
| | Lukáš Klein | 7$^8$ | 3 | 4 | 21 | Hugo Grenier | 6 | 6$^4$ | 6 |
| 21 | Hugo Grenier | 6$^6$ | 6 | 6 | | | | | |

#### Eighth qualifier

| First round | First round | First round | First round | Qualifying competition | Qualifying competition | Qualifying competition | Qualifying competition | Qualifying competition |
| 8 | Matteo Arnaldi | 6 | 6 | | | | | |
| | Filip Misolic | 1 | 4 | | | | | |
| | Filip Misolic | 1 | 4 | 8 | Matteo Arnaldi | 3 | 6 | 6 |
| | | | | 17 | Arthur Fils | 6 | 3 | 2 |
| WC | Reda Bennani | 2 | 2 | 17 | Arthur Fils | 6 | 3 | 2 |
| 17 | Arthur Fils | 6 | 6 | | | | | |

#### Ninth qualifier

| First round | First round | First round | First round | Qualifying competition | Qualifying competition | Qualifying competition | Qualifying competition |
| 9 | Roman Safiullin | 6 | 6 | | | | |
| | João Sousa | 2 | 2 | | | | |
| | João Sousa | 2 | 2 | 9 | Roman Safiullin | 6 | 7$^7$ |
| | | | | 16 | Sebastian Ofner | 4 | 6$^4$ |
| | Elias Ymer | 3 | 1 | 16 | Sebastian Ofner | 4 | 6$^4$ |
| 16 | Sebastian Ofner | 6 | 6 | | | | |

#### Tenth qualifier

| First round | First round | First round | First round | First round | Qualifying competition | Qualifying competition | Qualifying competition | Qualifying competition | Qualifying competition |
| 10 | Pavel Kotov | 6 | 3 | 7$^8$ | | | | | |
| | Kimmer Coppejans | 4 | 6 | 6$^6$ | | | | | |
| | Kimmer Coppejans | 4 | 6 | 6$^6$ | 10 | Pavel Kotov | 7$^9$ | 3 | 6$^3$ |
| | | | | | 13 | Yosuke Watanuki | 6$^7$ | 6 | 7$^7$ |
| | Federico Delbonis | 4 | 6$^5$ | | 13 | Yosuke Watanuki | 6$^7$ | 6 | 7$^7$ |
| 13 | Yosuke Watanuki | 6 | 7$^7$ | | | | | | |

#### Eleventh qualifier

| First round | First round | First round | First round | First round | Qualifying competition | Qualifying competition | Qualifying competition | Qualifying competition |
| 11 | Borna Gojo | 6 | 6 | | | | | |
| | Jan Choinski | 3 | 2 | | | | | |
| | Jan Choinski | 3 | 2 | | 11 | Borna Gojo | 7$^8$ | 6 |
| | | | | | 23 | Zsombor Piros | 6$^6$ | 2 |
| WC | Pablo Andújar | 6 | 1 | 2 | 23 | Zsombor Piros | 6$^6$ | 2 |
| 23 | Zsombor Piros | 3 | 6 | 6 | | | | |

#### Twelfth qualifier

| First round | First round | First round | First round | First round | Qualifying competition | Qualifying competition | Qualifying competition | Qualifying competition |
| 12 | Yannick Hanfmann | 6 | 6 | | | | | |
| | Maximilian Marterer | 2 | 4 | | | | | |
| | Maximilian Marterer | 2 | 4 | | 12 | Yannick Hanfmann | 6 | 6 |
| | | | | | WC | Arthur Cazaux | 2 | 4 |
| WC | Arthur Cazaux | 4 | 6 | 7$^8$ | WC | Arthur Cazaux | 2 | 4 |
| 24 | Pedro Martínez | 6 | 2 | 6$^6$ | | | | |