# 2021 Mutua Madrid Open – Men's singles

Alexander Zverev defeated Matteo Berrettini in the final, 6–7$^{(8–10)}$, 6–4, 6–3 to win the men's singles tennis title at the 2021 Madrid Open. It was his fourth Masters 1000 title, his first since the 2018 Madrid Open, and his 15th career ATP Tour singles title overall.
Novak Djokovic was the reigning champion from when the tournament was last held in 2019, but did not participate.
Following the third-round eliminations of Daniil Medvedev and Stefanos Tsitsipas, respectively, a first-time Masters 1000 singles finalist from the bottom half of the draw was guaranteed; Berrettini went on to become that player.

## Seeds

The top eight seeds received a bye into the second round.
    01. Rafael Nadal (quarterfinals)
    02. Daniil Medvedev (third round)
    03. Dominic Thiem (semifinals)
    04. Stefanos Tsitsipas (third round)
    05. Alexander Zverev (champion)
    06. Andrey Rublev (third round)
    07. Diego Schwartzman (second round)
    08. Matteo Berrettini (final)
    09. Roberto Bautista Agut (second round)
    10. Pablo Carreño Busta (first round)
    11. Denis Shapovalov (second round)
    12. Hubert Hurkacz (first round)
    13. Grigor Dimitrov (first round)
    14. Jannik Sinner (second round)
    15. Félix Auger-Aliassime (first round)
    16. Cristian Garín (quarterfinals)
Click on the seed number of a player to go to their draw section.

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final | Final | Final |
| 1 | Rafael Nadal | 4 | 4 | | | | | | | | | | |
| 5 | Alexander Zverev | 6 | 6 | | | | | | | | | | |
| 5 | Alexander Zverev | 6 | 6 | | 5 | Alexander Zverev | 6 | 6 | | | | | |
| | | | | | 3 | Dominic Thiem | 3 | 4 | | | | | |
| 3 | Dominic Thiem | 3 | 6 | 6 | 3 | Dominic Thiem | 3 | 4 | | | | | |
| | John Isner | 6 | 3 | 4 | | | | | | | | | |
| | John Isner | 6 | 3 | 4 | | | | | 5 | Alexander Zverev | 6$^8$ | 6 | 6 |
| | | | | | | | | | 8 | Matteo Berrettini | 7$^{10}$ | 4 | 3 |
| | Alexander Bublik | 5 | 1 | | | | | | | | | | | 8 | Matteo Berrettini | 7$^{10}$ | 4 | 3 |
| | Casper Ruud | 7 | 6 | | | | | | | | | | |
| | Casper Ruud | 7 | 6 | | | Casper Ruud | 4 | 4 | | | | | |
| | | | | | 8 | Matteo Berrettini | 6 | 6 | | | | | |
| 8 | Matteo Berrettini | 5 | 6 | 6 | 8 | Matteo Berrettini | 6 | 6 | | | | | |
| 16 | Cristian Garín | 7 | 3 | 0 | | | | | | | | | |

### Top half
#### Section 1

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Third round | Third round | Third round | Third round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals |
| | | | | | 1 | R Nadal | 6 | 6 | | | | | | | | | |
| | A Mannarino | 4 | 0 | | WC | C Alcaraz | 1 | 2 | | | | | | | | | |
| WC | C Alcaraz | 6 | 6 | | | | | | | 1 | R Nadal | 6 | 6 | | | | |
| Q | A Popyrin | 6 | 7$^7$ | | | | | | | Q | A Popyrin | 3 | 3 | | | | |
| | J-L Struff | 3 | 6$^4$ | | Q | A Popyrin | 7$^7$ | 6 | | | | | | | | | |
| | G Pella | 2 | 4$^r$ | | 14 | J Sinner | 6$^5$ | 2 | | | | | | | | | |
| 14 | J Sinner | 6 | 4 | | | | | | | | | | | 1 | R Nadal | 4 | 4 |
| 12 | H Hurkacz | 7 | 6$^7$ | 3 | | | | | | | | | | 5 | A Zverev | 6 | 6 |
| | J Millman | 5 | 7$^9$ | 6 | | J Millman | 7$^7$ | 2 | 3 | | | | | | | | |
| | J Chardy | 6$^6$ | 7$^9$ | 2 | | D Evans | 6$^5$ | 6 | 6 | | | | | | | | |
| | D Evans | 7$^8$ | 6$^7$ | 6 | | | | | | | D Evans | 3 | 6$^3$ | | | | |
| | K Khachanov | 7$^8$ | 2 | 2 | | | | | | 5 | A Zverev | 6 | 7$^7$ | | | | |
| | K Nishikori | 6$^6$ | 6 | 6 | | K Nishikori | 3 | 2 | | | | | | | | | |
| | | | | | 5 | A Zverev | 6 | 6 | | | | | | | | | |

#### Section 2

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Third round | Third round | Third round | Third round | Third round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals |
| | | | | | 3 | D Thiem | 6 | 6 | | | | | | | | | | | |
| Q | P Andújar | 7$^{10}$ | 6$^4$ | 5 | Q | M Giron | 1 | 3 | | | | | | | | | | | |
| Q | M Giron | 6$^8$ | 7$^7$ | 7 | | | | | | 3 | D Thiem | 7$^9$ | 6 | | | | | | |
| | A de Minaur | 4 | 7 | 6 | | | | | | | A de Minaur | 6$^7$ | 4 | | | | | | |
| WC | J Munar | 6 | 5 | 1 | | A de Minaur | 6 | 3 | | | | | | | | | | | |
| | L Harris | 6 | 3 | 7$^7$ | | L Harris | 2 | 0$^r$ | | | | | | | | | | | |
| 13 | G Dimitrov | 3 | 6 | 6$^5$ | | | | | | | | | | | 3 | D Thiem | 3 | 6 | 6 |
| 9 | R Bautista Agut | 6 | 6$^3$ | 7 | | | | | | | | | | | | J Isner | 6 | 3 | 4 |
| Q | M Cecchinato | 2 | 7$^7$ | 5 | 9 | R Bautista Agut | 4 | 7$^7$ | 6$^6$ | | | | | | | | | | |
| | J Isner | 6 | 7$^8$ | | | J Isner | 6 | 6$^4$ | 7$^8$ | | | | | | | | | | |
| | M Kecmanović | 4 | 6$^6$ | | | | | | | | J Isner | 7$^7$ | 3 | 7$^7$ | | | | | |
| WC | P Martínez | 4 | 5 | | | | | | | 6 | A Rublev | 6$^4$ | 6 | 6$^4$ | | | | | |
| | T Paul | 6 | 7 | | | T Paul | 7$^7$ | 3 | 4 | | | | | | | | | | |
| | | | | | 6 | A Rublev | 6$^5$ | 6 | 6 | | | | | | | | | | |

### Bottom half
#### Section 3

| First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Third round | Third round | Third round | Third round | Quarterfinals | Quarterfinals | Quarterfinals |
| | | | | 7 | D Schwartzman | 6 | 4 | 1 | | | | | | | |
| | U Humbert | 5 | 4 | | A Karatsev | 2 | 6 | 6 | | | | | | | |
| | A Karatsev | 7 | 6 | | | | | | | A Karatsev | 4 | 3 | | | |
| | M Fucsovics | 6$^5$ | 3 | | | | | | | A Bublik | 6 | 6 | | | |
| | A Bublik | 7$^7$ | 6 | | A Bublik | 6 | 5 | 6 | | | | | | | |
| | D Lajović | 1 | 3 | 11 | D Shapovalov | 4 | 7 | 4 | | | | | | | |
| 11 | D Shapovalov | 6 | 6 | | | | | | | | | | A Bublik | 5 | 1 |
| 15 | F Auger-Aliassime | 1 | 4 | | | | | | | | | | C Ruud | 7 | 6 |
| | C Ruud | 6 | 6 | | C Ruud | 6 | 6 | | | | | | | | |
| LL | Y Nishioka | 6 | 6 | LL | Y Nishioka | 1 | 2 | | | | | | | | |
| | F Krajinović | 2 | 4 | | | | | | | C Ruud | 7$^7$ | 6 | | | |
| | N Basilashvili | 4 | 5 | | | | | | 4 | S Tsitsipas | 6$^4$ | 4 | | | |
| | B Paire | 6 | 7 | | B Paire | 1 | 2 | | | | | | | | |
| | | | | 4 | S Tsitsipas | 6 | 6 | | | | | | | | |

#### Section 4

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Third round | Third round | Third round | Third round | Third round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals |
| | | | | | 8 | M Berrettini | 6 | 6 | | | | | | | | | | | |
| Q | C Taberner | 6$^4$ | 6 | 3 | | F Fognini | 3 | 4 | | | | | | | | | | | |
| | F Fognini | 7$^7$ | 2 | 6 | | | | | | 8 | M Berrettini | 7$^7$ | 6 | | | | | | |
| | T Fritz | 5 | 7 | 4 | | | | | | Q | F Delbonis | 6$^4$ | 4 | | | | | | |
| | A Ramos Viñolas | 7 | 5 | 6 | | A Ramos Viñolas | 6$^5$ | 3 | | | | | | | | | | | |
| Q | F Delbonis | 3 | 6 | 6 | Q | F Delbonis | 7$^7$ | 6 | | | | | | | | | | | |
| 10 | P Carreño Busta | 6 | 4 | 3 | | | | | | | | | | | 8 | M Berrettini | 5 | 6 | 6 |
| 16 | C Garín | 6 | 6 | | | | | | | | | | | | 16 | C Garín | 7 | 3 | 0 |
| WC | F Verdasco | 1 | 4 | | 16 | C Garín | 6 | 6 | | | | | | | | | | | |
| | D Koepfer | 6 | 6 | | | D Koepfer | 3 | 4 | | | | | | | | | | | |
| | R Opelka | 4 | 4 | | | | | | | 16 | C Garín | 6 | 6$^2$ | 6 | | | | | |
| Q | P-H Herbert | 7$^7$ | 6$^4$ | 6$^4$ | | | | | | 2 | D Medvedev | 4 | 7$^7$ | 1 | | | | | |
| | A Davidovich Fokina | 6$^5$ | 7$^7$ | 7$^7$ | | A Davidovich Fokina | 6 | 4 | 2 | | | | | | | | | | |
| | | | | | 2 | D Medvedev | 4 | 6 | 6 | | | | | | | | | | |

## Qualifying
### Seeds

* Laslo Đere (first round)
* Yoshihito Nishioka (qualifying competition, retired, lucky loser)
* Jordan Thompson (first round)
* Tennys Sandgren (first round)
* Frances Tiafoe (first round)
* Sebastian Korda (first round)
* Stefano Travaglia (qualifying competition)
* Emil Ruusuvuori (first round)
* Egor Gerasimov (first round)
* Alexei Popyrin (qualified)
* Thiago Monteiro (first round)
* Federico Delbonis (qualified)
* Pablo Andújar (qualified)
* Radu Albot (first round)

### Qualifiers

* Federico Delbonis
* Marcos Giron
* Carlos Taberner
* Pierre-Hugues Herbert
* Marco Cecchinato
* Alexei Popyrin
* Pablo Andújar

### Lucky loser

* Yoshihito Nishioka

### Qualifying draw
#### First qualifier

| First round | First round | First round | First round | First round | Qualifying competition | Qualifying competition | Qualifying competition | Qualifying competition |
| 1 | Laslo Đere | 3 | 6 | 2 | | | | |
| | Juan Ignacio Londero | 6 | 3 | 6 | | | | |
| | Juan Ignacio Londero | 6 | 3 | 6 | | Juan Ignacio Londero | 4 | 4 |
| | | | | | 12 | Federico Delbonis | 6 | 6 |
| WC | Bernabé Zapata Miralles | 6$^5$ | 6$^5$ | | 12 | Federico Delbonis | 6 | 6 |
| 12 | Federico Delbonis | 7$^7$ | 7$^7$ | | | | | |

#### Second qualifier

| First round | First round | First round | First round | First round | Qualifying competition | Qualifying competition | Qualifying competition | Qualifying competition | Qualifying competition |
| 2 | Yoshihito Nishioka | 6 | 6 | | | | | | |
| | Pablo Cuevas | 4 | 4 | | | | | | |
| | Pablo Cuevas | 4 | 4 | | 2 | Yoshihito Nishioka | 7$^7$ | 4 | 0$^r$ |
| | | | | | | Marcos Giron | 6$^4$ | 6 | 0 |
| | Marcos Giron | 6 | 6$^{12}$ | 7$^7$ | | Marcos Giron | 6$^4$ | 6 | 0 |
| 11 | Thiago Monteiro | 4 | 7$^{14}$ | 6$^4$ | | | | | |

#### Third qualifier

| First round | First round | First round | First round | First round | Qualifying competition | Qualifying competition | Qualifying competition | Qualifying competition |
| 3 | Jordan Thompson | 6 | 6$^6$ | 2 | | | | |
| WC | Carlos Taberner | 3 | 7$^8$ | 6 | | | | |
| WC | Carlos Taberner | 3 | 7$^8$ | 6 | WC | Carlos Taberner | 6 | 6 |
| | | | | | | Lorenzo Musetti | 4 | 2 |
| | Lorenzo Musetti | 6 | 6 | | | Lorenzo Musetti | 4 | 2 |
| 14 | Radu Albot | 3 | 4 | | | | | |

#### Fourth qualifier

| First round | First round | First round | First round | Qualifying competition | Qualifying competition | Qualifying competition |
| 4 | Tennys Sandgren | 3 | 2 | | | |
| | Pierre-Hugues Herbert | 6 | 6 | | | |
| | Pierre-Hugues Herbert | 6 | 6 | Pierre-Hugues Herbert | 7$^7$ | 6 |
| | | | | Gianluca Mager | 6$^4$ | 4 |
| | Gianluca Mager | 6 | 6 | Gianluca Mager | 6$^4$ | 4 |
| 9 | Egor Gerasimov | 4 | 3 | | | |

#### Fifth qualifier

| First round | First round | First round | First round | Qualifying competition | Qualifying competition | Qualifying competition | Qualifying competition |
| 5 | Frances Tiafoe | 6$^4$ | 2 | | | | |
| | Marco Cecchinato | 7$^7$ | 6 | | | | |
| | Marco Cecchinato | 7$^7$ | 6 | Marco Cecchinato | 4 | 6 | 6 |
| | | | | Roberto Carballés Baena | 6 | 0 | 3 |
| | Roberto Carballés Baena | 6 | 6 | Roberto Carballés Baena | 6 | 0 | 3 |
| 8 | Emil Ruusuvuori | 2 | 3 | | | | |

#### Sixth qualifier

| First round | First round | First round | First round | First round | Qualifying competition | Qualifying competition | Qualifying competition | Qualifying competition |
| 6 | Sebastian Korda | 6$^3$ | 4 | | | | | |
| WC | Arthur Cazaux | 7$^7$ | 6 | | | | | |
| WC | Arthur Cazaux | 7$^7$ | 6 | | WC | Arthur Cazaux | 5 | 6$^0$ |
| | | | | | 10 | Alexei Popyrin | 7 | 7$^7$ |
| | Federico Coria | 7$^7$ | 4 | 3 | 10 | Alexei Popyrin | 7 | 7$^7$ |
| 10 | Alexei Popyrin | 6$^4$ | 6 | 6 | | | | |

#### Seventh qualifier

| First round | First round | First round | First round | First round | Qualifying competition | Qualifying competition | Qualifying competition | Qualifying competition | Qualifying competition |
| 7 | Stefano Travaglia | 5 | 6 | 7 | | | | | |
| WC | Carlos Gimeno Valero | 7 | 1 | 5 | | | | | |
| WC | Carlos Gimeno Valero | 7 | 1 | 5 | 7 | Stefano Travaglia | 7$^7$ | 5 | 3 |
| | | | | | 13 | Pablo Andújar | 6$^3$ | 7 | 6 |
| | Mikhail Kukushkin | 3 | 4 | | 13 | Pablo Andújar | 6$^3$ | 7 | 6 |
| 13 | Pablo Andújar | 6 | 6 | | | | | | |

## ATP singles main-draw entrants
### Seeds

The following are the seeded players. Seedings are based on ATP rankings as of 26 April 2021. Rankings and points before are as of 3 May 2021.
| Seed | Rank | Player | Points before | Points defending | Points won | Points after | Status |
| 1 | 2 | Rafael Nadal | 9,810 | 360 | 180 | 9,630 | Quarterfinals lost to Alexander Zverev [5] |
| 2 | 3 | Daniil Medvedev | 9,700 | 10 | 90 | 9,780 | Third round lost to Cristian Garín [16] |
| 3 | 4 | Dominic Thiem | 8,365 | 360 | 360 | 8,365 | Semifinals lost to Alexander Zverev [5] |
| 4 | 5 | Stefanos Tsitsipas | 7,910 | 390 | 90 | 7,610 | Third round lost to Casper Ruud |
| 5 | 6 | Alexander Zverev | 6,125 | 180 | 1,000 | 6,945 | Champion, defeated Matteo Berrettini [8] |
| 6 | 8 | Andrey Rublev | 6,000 | 90 | 90 | 6,000 | Third round lost to John Isner |
| 7 | 9 | Diego Schwartzman | 3,765 | 67 | 45 | 3,743 | Second round lost to Aslan Karatsev |
| 8 | 10 | Matteo Berrettini | 3,493 | 45 | 600 | 4,048 | Runner-up, lost to Alexander Zverev [5] |
| 9 | 11 | Roberto Bautista Agut | 3,090 | 10 | 45 | 3,125 | Second round lost to John Isner |
| 10 | 12 | Pablo Carreño Busta | 3,015 | 10 | 10 | 3,015 | First round lost to Federico Delbonis [Q] |
| 11 | 14 | Denis Shapovalov | 2,820 | 10 | 45 | 2,855 | Second round lost to Alexander Bublik |
| 12 | 16 | Hubert Hurkacz | 2,600 | 67 | 10 | 2,543 | First round lost to John Millman |
| 13 | 17 | Grigor Dimitrov | 2,576 | 10 | 10 | 2,576 | First round lost to Lloyd Harris |
| 14 | 18 | Jannik Sinner | 2,524 | 24 | 45 | 2,545 | Second round lost to Alexei Popyrin [Q] |
| 15 | 20 | Félix Auger-Aliassime | 2,418 | 32 | 10 | 2,396 | First round lost to Casper Ruud |
| 16 | 22 | Cristian Garín | 2,215 | 45 | 180 | 2,350 | Quarterfinals lost to Matteo Berrettini [8] |

### Other entrants

The following players received wildcards into the main draw:
* Carlos Alcaraz
* Pedro Martínez
* Jaume Munar
* Fernando Verdasco
The following players received entry from the qualifying draw:
* Pablo Andújar
* Marco Cecchinato
* Federico Delbonis
* Marcos Giron
* Pierre-Hugues Herbert
* Alexei Popyrin
* Carlos Taberner
The following player received entry as a lucky loser:
* Yoshihito Nishioka

### Withdrawals
#### Before the tournament

* Marin Čilić → replaced by Tommy Paul
* Borna Ćorić → replaced by Jérémy Chardy
* Novak Djokovic → replaced by Alejandro Davidovich Fokina
* Roger Federer → replaced by Miomir Kecmanović
* David Goffin → replaced by Lloyd Harris
* Gaël Monfils → replaced by Guido Pella
* Milos Raonic → replaced by Yoshihito Nishioka
* Lorenzo Sonego → replaced by Dominik Koepfer
* Stan Wawrinka → replaced by Albert Ramos Viñolas

### Retirements

* Lloyd Harris
* Guido Pella