# National Register of Historic Places listings in San Juan, Puerto Rico

This portion of National Register of Historic Places listings in Puerto Rico covers the municipality of San Juan.
Names of places given are as appear in the National Register, reflecting name as given in NRHP application at the date of listing. Note, the National Register name system does not accommodate Spanish á, ñ and other letters.
This National Park Service list is complete through NPS recent listings posted February 7, 2025.

## Current listings

| | Name on the Register | Image | Date listed | Location | Barrio | Description |
| 1 | Acueducto de San Juan | Acueducto de San Juan | June 21, 2007 (#07000585) | Flamboyán St. 18°23′21″N 66°03′32″W﻿ / ﻿18.3892°N 66.0588°W﻿ / 18.3892; -66.0588﻿ (Acueducto de San Juan) | El Cinco | Spanish-built waterworks from 1846 that was integral for the development of Río Piedras, includes an aqueduct, filtration plant and hydrological structures that make use of the nearby Piedras River. |
| 2 | Administration Building | Administration Building | October 26, 1983 (#83004195) | University of the Sacred Heart campus, Rosales and San Antonio Sts. 18°26′33″N 66°03′32″W﻿ / ﻿18.4425°N 66.0589°W﻿ / 18.4425; -66.0589﻿ (Administration Building) | Santurce | University of the Sacred Heart administration building and chapel built in a Classical Revival style in 1906. Also known as Portico and Chapel of the Sacred Heart University. |
| 3 | Antiguo Casino de Puerto Rico | Antiguo Casino de Puerto Rico More images | September 22, 1977 (#77001554) | 1 Ponce de León Ave. 18°27′58″N 66°06′41″W﻿ / ﻿18.4661°N 66.1114°W﻿ / 18.4661; -66.1114﻿ (Antiguo Casino de Puerto Rico) | San Juan Antiguo | Beaux Arts casino building from 1917, used as an officers' club, music school, cultural headquarters, reception hall and event venue by the United States Army and the government of Puerto Rico throughout its history. |
| 4 | Biblioteca Carnegie | Biblioteca Carnegie More images | October 20, 1983 (#83004196) | Ponce de León Ave., Puerta de Tierra 18°27′59″N 66°06′31″W﻿ / ﻿18.4664°N 66.1085°W﻿ / 18.4664; -66.1085﻿ (Biblioteca Carnegie) | San Juan Antiguo | Classical Revival Carnegie library building from 1915 that was the first purpose-built library in the territory. |
| 5 | Hiram Bithorn Municipal Stadium | Hiram Bithorn Municipal Stadium More images | January 22, 2014 (#13001118) | Franklin Delano Roosevelt Ave. 18°25′00″N 66°04′23″W﻿ / ﻿18.4167°N 66.0731°W﻿ / 18.4167; -66.0731﻿ (Hiram Bithorn Municipal Stadium) | Hato Rey Norte | Ballpark from 1962 designed by Pedro Miranda and built to replace the smaller Sixto Escobar Stadium. In addition to serving as an event and concert venue, it has also served as the territory's national stadium and hosted the 1979 Pan American Games. |
| 6 | El Capitolio de Puerto Rico | El Capitolio de Puerto Rico More images | November 18, 1977 (#77001555) | Ponce de León and Muñoz Rivera Avenues 18°28′00″N 66°06′21″W﻿ / ﻿18.4668°N 66.1059°W﻿ / 18.4668; -66.1059﻿ (El Capitolio de Puerto Rico) | San Juan Antiguo | The seat of government of Puerto Rico, a Classical Revival / Beaux Arts building from 1929, designed by Rafael Carmoega and inspired by the Low Memorial Library from Columbia University. Often referred to as the Palace of the Laws (Palacio de las Leyes). |
| 7 | Carcel de Puerta de Tierra | Carcel de Puerta de Tierra More images | August 11, 1976 (#76002253) | Ponce de León Ave., Stop 8, Puerta de Tierra 18°27′49″N 66°05′32″W﻿ / ﻿18.4636°N 66.0923°W﻿ / 18.4636; -66.0923﻿ (Carcel de Puerta de Tierra) | San Juan Antiguo | Spanish Neoclassical building from 1887 that has functioned as a prison, a Bacardi factory and public library. Today it hosts the Puerto Rico General Archives. |
| 8 | Casa Dr. Bailey K. Ashford | Casa Dr. Bailey K. Ashford | September 16, 2022 (#100008175) | 1312 Ashford Ave. 18°27′18″N 66°04′10″W﻿ / ﻿18.455034°N 66.069346°W﻿ / 18.455034; -66.069346﻿ (Casa Dr. Bailey K. Ashford) | Santurce | Historic house and former residence of physician and Nobel Prize in Medicine nominee Bailey Ashford, former member of the Puerto Rico School of Tropical Medicine and founder of the Puerto Rico Anemia Commission. |
| 9 | Casa de España | Casa de España More images | July 5, 1983 (#83002294) | Ponce de León Ave. 18°27′59″N 66°06′29″W﻿ / ﻿18.4664°N 66.1080°W﻿ / 18.4664; -66.1080﻿ (Casa de España) | San Juan Antiguo | Exotic / Moorish Revival house from 1932, designed by Pedro Adolfo de Castro for a private Spanish-Puerto Rican social club. It includes a replica of the Court of the Lions from the Alhambra. |
| 10 | Casa Gonzalez Cuyar | Casa Gonzalez Cuyar | March 4, 2024 (#100010033) | #225 Calle del Parque 18°26′50″N 66°03′51″W﻿ / ﻿18.4473°N 66.0643°W﻿ / 18.4473; -66.0643﻿ (Casa Gonzalez Cuyar) | | |
| 11 | Casa Klumb | Casa Klumb | November 14, 1997 (#97001307) | 1 Ramón B. López Ave. 18°23′58″N 66°02′06″W﻿ / ﻿18.3995°N 66.0350°W﻿ / 18.3995; -66.0350﻿ (Casa Klumb) | Oriente | Modernist home from 1947 designed and lived by Henry Klumb until his death. It was destroyed by a fire in 2020. |
| 12 | Casa Dra. Concha Meléndez Ramírez | Casa Dra. Concha Meléndez Ramírez More images | June 30, 2011 (#11000414) | 1400 Vilá Mayo St., at Manuel Rodríguez Serra St. 18°27′10″N 66°04′02″W﻿ / ﻿18.4527°N 66.0673°W﻿ / 18.4527; -66.0673﻿ (Casa Dra. Concha Meléndez Ramírez) | Santurce | Longtime home of writer, educator and first female member of the Puerto Rican Academy of Languages Concha Meléndez. The house itself is notable for its 1930s Spanish Colonial Revival architecture. Also a National Historic Landmark. |
| 13 | Casa Vigil | Casa Vigil More images | July 23, 2018 (#100002694) | 1018 Calle Ferrocarril 18°24′00″N 66°02′59″W﻿ / ﻿18.4000°N 66.0497°W﻿ / 18.4000; -66.0497﻿ (Casa Vigil) | Pueblo | Historic vernacular residence from the late-19th century representative of the last wooden houses in the city before the construction trends shifted to concrete. |
| 14 | Central High School | Central High School More images | August 4, 1987 (#87001309) | Ponce de León Ave. 18°26′53″N 66°04′11″W﻿ / ﻿18.4481°N 66.0698°W﻿ / 18.4481; -66.0698﻿ (Central High School) | Santurce | Spanish Renaissance-inspired building from 1925. |
| 15 | Church of San Mateo de Cangrejos of Santurce | Church of San Mateo de Cangrejos of Santurce More images | January 2, 1985 (#85000044) | Corner of San Jorge St. and Eduardo Conde Ave. 18°26′40″N 66°03′48″W﻿ / ﻿18.4445°N 66.0634°W﻿ / 18.4445; -66.0634﻿ (Church of San Mateo de Cangrejos of Santurce) | Santurce | Historic 1832 parish church designed by Pedro Cobreros. Part of the Historic Churches of Puerto Rico MPS. |
| 16 | Church, School, Convent and Parish House of San Agustín | Church, School, Convent and Parish House of San Agustín More images | December 30, 1985 (#85003194) | 265 Ponce de León Ave. 18°27′56″N 66°05′56″W﻿ / ﻿18.4656°N 66.0989°W﻿ / 18.4656; -66.0989﻿ (Church, School, Convent and Parish House of San Agustín) | San Juan Antiguo | 1915 concrete church and adjacent Augustinian convent and Catholic school located in the Puerta de Tierra Historic District. |
| 17 | Colegio de las Madres del Sagrado Corazón | Colegio de las Madres del Sagrado Corazón | November 25, 1985 (#85002908) | 951 Ponce de León Ave. 18°27′15″N 66°04′46″W﻿ / ﻿18.4543°N 66.0794°W﻿ / 18.4543; -66.0794﻿ (Colegio de las Madres del Sagrado Corazón) | Santurce | Former Catholic convent from 1880, now part of the Conservatory of Music of Puerto Rico. |
| 18 | Condado Vanderbilt Hotel | Condado Vanderbilt Hotel More images | November 25, 2005 (#08001110) | 1055 Ashford Ave. 18°27′31″N 66°04′34″W﻿ / ﻿18.4587°N 66.0760°W﻿ / 18.4587; -66.0760﻿ (Condado Vanderbilt Hotel) | Santurce | Warren and Wetmore-designed Mission/Spanish Revival style hotel from 1919 that marked the beginning of the large-scale tourism industry in Puerto Rico. |
| 19 | Rafael Cordero Graded School | Rafael Cordero Graded School | November 19, 2020 (#100005816) | Calle Aurora Esq. Horae Prada 15 18°27′04″N 66°04′51″W﻿ / ﻿18.4511°N 66.0809°W﻿ / 18.4511; -66.0809﻿ (Rafael Cordero Graded School) | Santurce | A historic vocational high school building. |
| 20 | Distrito Histórico del Viejo San Juan – Old San Juan Historic District | Distrito Histórico del Viejo San Juan – Old San Juan Historic District More images | October 10, 1972 (#72001553) | Northwest triangle of San Juan Islet; also roughly bounded by Muñoz Rivera and Ponce de León Avenues, Paseo de Covadonga, and J. A. Corretejer and Recinto Sur Streets 18°27′58″N 66°06′55″W﻿ / ﻿18.4661°N 66.1154°W﻿ / 18.4661; -66.1154﻿ (Distrito Histórico del Viejo San Juan – Old San Juan Historic District) | San Juan Antiguo | Historic district that represents the oldest permanent European-established settlement in Puerto Rico and in the United States jurisdiction. Second set of boundaries represents a boundary increase of July 30, 2012 (#12000465). Designated a National Historic Landmark District on February 27, 2013 (#13000284). |
| 21 | Edificio Aboy | Edificio Aboy More images | September 28, 2001 (#01001069) | 603 Aboy St. 18°27′15″N 66°04′51″W﻿ / ﻿18.4541°N 66.0809°W﻿ / 18.4541; -66.0809﻿ (Edificio Aboy) | Santurce | Art Deco building from 1937, also known as Le Faro, designed by Jorge Julia Pasarell. |
| 22 | Edificio Comunidad de Orgullo Gay de Puerto Rico | Edificio Comunidad de Orgullo Gay de Puerto Rico | May 2, 2016 (#16000237) | 3 Saldaña St. 18°24′02″N 66°03′07″W﻿ / ﻿18.4006°N 66.0519°W﻿ / 18.4006; -66.0519﻿ (Edificio Comunidad de Orgullo Gay de Puerto Rico) | Pueblo | Mediterranean Revival apartment building and former LGBT community center located in downtown Río Piedras that historically represents the first organized attempt to confront discrimination against the local LGBTQ community. |
| 23 | Edificio del Valle | Edificio del Valle | November 20, 2004 (#04001243) | 1118 Ponce de León Ave. 18°27′04″N 66°04′31″W﻿ / ﻿18.4512°N 66.0754°W﻿ / 18.4512; -66.0754﻿ (Edificio del Valle) | Santurce | Mixed-use Mission/Spanish Revival building from 1941, designed by Rafael Carmoega Morales. |
| 24 | Edificio Patio Español | Edificio Patio Español More images | February 18, 2005 (#05000061) | 153 Cruz St. 18°27′57″N 66°06′58″W﻿ / ﻿18.465927°N 66.116224°W﻿ / 18.465927; -66.116224﻿ (Edificio Patio Español) | San Juan Antiguo | Mission/Spanish Revival, Eclectic building from 1937, also known as La Filarmonica, designed by Eduardo Fossas López. |
| 25 | Edificio Victory Garden | Edificio Victory Garden | October 13, 2004 (#04001149) | 1001 Ponce de León Ave., corner of Elisa Colberg St. 18°27′13″N 66°04′43″W﻿ / ﻿18.453514°N 66.078582°W﻿ / 18.453514; -66.078582﻿ (Edificio Victory Garden) | Santurce | Mission/Spanish Revival building from 1936, designed by Pedro Adolfo de Castro. |
| 26 | Escuela Brambaugh | Escuela Brambaugh | May 5, 1989 (#89000324) | San Juan Bautista St. and Ponce de León Ave. 18°27′55″N 66°05′44″W﻿ / ﻿18.465266°N 66.095597°W﻿ / 18.465266; -66.095597﻿ (Escuela Brambaugh) | San Juan Antiguo | From 1913, also known as Puerta de Tierra Public School. |
| 27 | Escuela Graduada José Celso Barbosa | Escuela Graduada José Celso Barbosa | May 19, 1989 (#89000406) | Ponce de León Ave. 18°27′57″N 66°06′04″W﻿ / ﻿18.465928°N 66.101217°W﻿ / 18.465928; -66.101217﻿ (Escuela Graduada José Celso Barbosa) | San Juan Antiguo | Classical Revival style school from 1927. |
| 28 | Escuela Ruiz Belvis | Escuela Ruiz Belvis | August 31, 2022 (#100008115) | Fernandez Juncos Ave. (formerly known as Carretera Nueva), Stop 16 1/2 $^{Coordinatesmissing}$ | | |
| 29 | El Falansterio de Puerta de Tierra | El Falansterio de Puerta de Tierra More images | May 3, 1984 (#84003166) | Bounded by railroad right-of-way, Fernández Juncos Avenue, and Matías Ledesma and San Juan Bautista Streets 18°27′48″N 66°05′47″W﻿ / ﻿18.463390°N 66.096414°W﻿ / 18.463390; -66.096414﻿ (El Falansterio de Puerta de Tierra) | San Juan Antiguo | New Deal era Art Deco public housing complex from 1937. Originally known as the Puerta de Tierra Tenement Group Project A and established by the FERA-funded Puerto Rico Reconstruction Administration. |
| 30 | Faro del Morro | Faro del Morro More images | October 22, 1981 (#81000693) | Summit of San Felipe del Morro Castle 18°28′16″N 66°07′25″W﻿ / ﻿18.471053°N 66.123614°W﻿ / 18.471053; -66.123614﻿ (Faro del Morro) | San Juan Antiguo | Oldest lighthouse in Puerto Rico, the current Moorish Revival-style version was however first lit in 1908. Located in Castillo San Felipe del Morro. |
| 31 | Figueroa Apartments | Figueroa Apartments | September 14, 2000 (#00001124) | 601 Fernández Juncos Ave. 18°27′26″N 66°05′12″W﻿ / ﻿18.457184°N 66.086744°W﻿ / 18.457184; -66.086744﻿ (Figueroa Apartments) | Santurce | Art Deco building from 1935 designed by Armando Morales Cano. |
| 32 | La Fortaleza | La Fortaleza More images | October 15, 1966 (#66000951) | Between San Juan Bay and Recinto Oeste St., at Fortaleza St. 18°27′51″N 66°07′09″W﻿ / ﻿18.464201°N 66.119294°W﻿ / 18.464201; -66.119294﻿ (La Fortaleza) | San Juan Antiguo | Former fortress from 1533, also known as the Santa Catalina Palace, part of the fortification system of San Juan it is now the official residence of the governor of Puerto Rico and the oldest executive mansion in continuous use in the Western Hemisphere. |
| 33 | Fortín de San Gerónimo de Boquerón | Fortín de San Gerónimo de Boquerón More images | October 11, 1983 (#83004199) | Puerta de Tierra 18°27′46″N 66°05′03″W﻿ / ﻿18.462841°N 66.084199°W﻿ / 18.462841; -66.084199﻿ (Fortín de San Gerónimo de Boquerón) | San Juan Antiguo | Small fortress from 1791, built at El Boquerón, in the entrance of Condado Lagoon, to provide defense against land and northeast attacks. Part of the Línea Avanzada historic district. Today it is preserved as the Military History Museum of Puerto Rico. |
| 34 | La Giralda | La Giralda | August 11, 2008 (#08000786) | 651 José Martí St. 18°27′19″N 66°05′07″W﻿ / ﻿18.455288°N 66.085308°W﻿ / 18.455288; -66.085308﻿ (La Giralda) | Santurce | Classical Revival and Victorian residence from 1910, designed by Francisco Valinés Cofresí. |
| 35 | Gran Logia Espiritual Número 1 | Gran Logia Espiritual Número 1 | June 8, 2008 (#06000507) | 1612 Antonsanti St. 18°26′46″N 66°03′52″W﻿ / ﻿18.446077°N 66.064383°W﻿ / 18.446077; -66.064383﻿ (Gran Logia Espiritual Número 1) | Santurce | Classical Revival-style Spiritualist meeting hall from 1910. |
| 36 | Hotel Normandie | Hotel Normandie More images | August 29, 1980 (#80004295) | Ponce de León Ave. and San Gerónimo St. 18°27′52″N 66°05′15″W﻿ / ﻿18.464493°N 66.087412°W﻿ / 18.464493; -66.087412﻿ (Hotel Normandie) | San Juan Antiguo | Hotel that is a spectacular example of Streamline Moderne architecture, inspired by the Art Deco-style design of the ship SS Normandie. |
| 37 | House at 659 Concordia Street | House at 659 Concordia Street | October 18, 1991 (#91001501) | 659 Concordia St., Miramar 18°27′09″N 66°04′56″W﻿ / ﻿18.452497°N 66.082298°W﻿ / 18.452497; -66.082298﻿ (House at 659 Concordia Street) | Santurce | Mission/Spanish Revival house from 1935, designed by Joseph O'Kelly. |
| 38 | House at 659 La Paz Street | House at 659 La Paz Street | January 30, 1992 (#91002007) | 659 La Paz St., Miramar 18°27′10″N 66°04′58″W﻿ / ﻿18.452857°N 66.082787°W﻿ / 18.452857; -66.082787﻿ (House at 659 La Paz Street) | Santurce | Mission/Spanish Revival house from 1928, designed by Pedro Adolfo de Castro. |
| 39 | House at 663 La Paz Street | House at 663 La Paz Street | October 18, 1991 (#91001500) | 663 La Paz St., Miramar 18°27′09″N 66°04′58″W﻿ / ﻿18.452633°N 66.082882°W﻿ / 18.452633; -66.082882﻿ (House at 663 La Paz Street) | Santurce | Another Mission/Spanish Revival house designed by Pedro Adolfo de Castro. |
| 40 | House at 665 McKinley Street | House at 665 McKinley Street | October 19, 1991 (#91001502) | 665 McKinley St., Miramar 18°27′19″N 66°05′02″W﻿ / ﻿18.455259°N 66.083858°W﻿ / 18.455259; -66.083858﻿ (House at 665 McKinley Street) | Santurce | Vernacular Spanish Creole house from 1906. |
| 41 | Instituto Loaiza Cordero para Ninos Ciegos Historic District – Distrito Historico Instituto Loaiza Cordero para Ninos Ciegos | Instituto Loaiza Cordero para Ninos Ciegos Historic District – Distrito Historico Instituto Loaiza Cordero para Ninos Ciegos | October 23, 2018 (#100002935) | 1312 Fernández Juncos Ave. 18°26′50″N 66°04′27″W﻿ / ﻿18.447157°N 66.074081°W﻿ / 18.447157; -66.074081﻿ (Instituto Loaiza Cordero para Ninos Ciegos Historic District – Distrito Historico Instituto Loaiza Cordero para Ninos Ciegos) | Santurce | Former Mediterranean Revival-style hospital and school complex for blind children founded by Loaiza Cordero del Rosario in 1925. |
| 42 | Rafael M. Labra High School | Rafael M. Labra High School More images | August 4, 1987 (#87001308) | Ponce de León and Roberto H. Todd Aves. 18°27′00″N 66°04′28″W﻿ / ﻿18.450072°N 66.074406°W﻿ / 18.450072; -66.074406﻿ (Rafael M. Labra High School) | Santurce | Georgian style school building from 1916. Now functions as the Puerto Rico Museum of Contemporary Art. |
| 43 | Línea Avanzada | Línea Avanzada More images | September 25, 1997 (#97001136) | Eastern portion of the San Juan Islet 18°27′53″N 66°05′26″W﻿ / ﻿18.464645°N 66.090544°W﻿ / 18.464645; -66.090544﻿ (Línea Avanzada) | San Juan Antiguo | Defensive fortification system established in 1797 to defend the city of San Juan from land-based and northeastern pirate and foreign attacks. Built to complement the fortification systems of northwestern San Juan. |
| 44 | Miami Building | Miami Building More images | August 23, 1984 (#84003169) | 868 Ashford Ave. 18°27′37″N 66°04′50″W﻿ / ﻿18.460336°N 66.080441°W﻿ / 18.460336; -66.080441﻿ (Miami Building) | Santurce | Art Deco building from 1936, designed by Pedro Méndez Mercado. |
| 45 | Luis Muñoz Rivera Park | Luis Muñoz Rivera Park More images | November 14, 2007 (#07001195) | Ponce de León Ave., Stop 8, Puerta de Tierra 18°27′52″N 66°05′28″W﻿ / ﻿18.464406°N 66.090986°W﻿ / 18.464406; -66.090986﻿ (Luis Muñoz Rivera Park) | San Juan Antiguo | Park with Beaux Arts and Picturesque architecture and landscape design. |
| 46 | Mural "La Familia" | Mural "La Familia" | October 23, 2017 (#100001763) | 2030 Avenida Borinquen 18°26′15″N 66°03′18″W﻿ / ﻿18.437530°N 66.055015°W﻿ / 18.437530; -66.055015﻿ (Mural "La Familia") | Santurce | |
| 47 | General Norzagaray Bridge | General Norzagaray Bridge More images | July 19, 1995 (#95000833) | Highway 873, km 0.8, spanning the Quebrada Frailes 18°21′07″N 66°05′29″W﻿ / ﻿18.351816°N 66.091420°W﻿ / 18.351816; -66.091420﻿ (General Norzagaray Bridge) | Caimito and Tortugo | Brick barrel vault bridge from 1855, known also as Puente de Los Frailes |
| 48 | Nuestra Señora de Lourdes Chapel | Nuestra Señora de Lourdes Chapel More images | September 27, 1984 (#84003171) | Ponce de León and Miramar Aves. 18°27′23″N 66°05′07″W﻿ / ﻿18.456394°N 66.085148°W﻿ / 18.456394; -66.085148﻿ (Nuestra Señora de Lourdes Chapel) | Santurce | Neo-Gothic style chapel from 1908, designed by Antonin Nechodoma |
| 49 | Martín Peña Bridge | Martín Peña Bridge More images | August 27, 2008 (#08000856) | Highway 25, km 8 18°26′00″N 66°03′33″W﻿ / ﻿18.433462°N 66.059045°W﻿ / 18.433462; -66.059045﻿ (Martín Peña Bridge) | Santurce, Hato Rey Norte, and Hato Rey Central | Art Deco style bridge from 1939, designed by Cecilio Delgado and others |
| 50 | Polvorín de Miraflores | Polvorín de Miraflores More images | March 9, 1984 (#84003172) | 66 Aramania St., Old Miramar Naval Base 18°26′58″N 66°05′38″W﻿ / ﻿18.449514°N 66.093904°W﻿ / 18.449514; -66.093904﻿ (Polvorín de Miraflores) | Santurce | A gunpowder magazine from 1776 |
| 51 | Puerta de Tierra Historic District – Distrito Histórico de Puerta de Tierra | Puerta de Tierra Historic District – Distrito Histórico de Puerta de Tierra More images | October 15, 2019 (#100002936) | San Juan Islet to the east of the Old San Juan Historic District 18°27′51″N 66°05′54″W﻿ / ﻿18.464040°N 66.098390°W﻿ / 18.464040; -66.098390﻿ (Puerta de Tierra Historic District – Distrito Histórico de Puerta de Tierra) | San Juan Antiguo | |
| 52 | Puerto Rico Ilustrado – Edificio El Mundo | Puerto Rico Ilustrado – Edificio El Mundo More images | September 25, 1997 (#97001137) | 254 San José St. 18°27′51″N 66°07′01″W﻿ / ﻿18.464067°N 66.117004°W﻿ / 18.464067; -66.117004﻿ (Puerto Rico Ilustrado – Edificio El Mundo) | San Juan Antiguo | From 1923 |
| 53 | Puerto Rico Island Penitentiary | Puerto Rico Island Penitentiary | March 7, 2003 (#03000100) | South of Highway 21 18°23′19″N 66°04′15″W﻿ / ﻿18.388649°N 66.070756°W﻿ / 18.388649; -66.070756﻿ (Puerto Rico Island Penitentiary) | Monacillo Urbano | Built 1933, closed 2004, demolished 2015 |
| 54 | Residencia Aboy–Lompre | Residencia Aboy–Lompre | March 22, 1989 (#88001304) | 900 Ponce de León Ave. 18°27′16″N 66°04′51″W﻿ / ﻿18.454349°N 66.080696°W﻿ / 18.454349; -66.080696﻿ (Residencia Aboy–Lompre) | Santurce | A Prairie School style house from 1919, designed by Antonin Nechodoma and others |
| 55 | Residencia de Señoritas Universidad de Puerto Rico, Río Piedras | Residencia de Señoritas Universidad de Puerto Rico, Río Piedras More images | July 23, 2018 (#100002695) | Near the intersection of Gándara and Barbosa Aves. 18°24′09″N 66°02′48″W﻿ / ﻿18.402542°N 66.046776°W﻿ / 18.402542; -66.046776﻿ (Residencia de Señoritas Universidad de Puerto Rico, Río Piedras) | Universidad | |
| 56 | Residencia Luis Muñoz Marín | Residencia Luis Muñoz Marín | September 29, 2011 (#11000712) | Highway 877, km 0.4 18°23′12″N 66°01′42″W﻿ / ﻿18.386667°N 66.028333°W﻿ / 18.386667; -66.028333﻿ (Residencia Luis Muñoz Marín) | Sabana Llana Sur | |
| 57 | Río Piedras Bridge | Río Piedras Bridge More images | July 19, 1995 (#95000832) | Highway 8839, km 12.5 18°23′40″N 66°03′21″W﻿ / ﻿18.394386°N 66.055958°W﻿ / 18.394386; -66.055958﻿ (Río Piedras Bridge) | El Cinco and Hato Rey Sur | A brick barrel vault bridge from 1853 |
| 58 | Rum Pilot Plant | Upload image | July 26, 2010 (#10000501) | Highway 1, University of Puerto Rico Agricultural Experiment Station 18°23′46″N 66°03′48″W﻿ / ﻿18.396115°N 66.063393°W﻿ / 18.396115; -66.063393﻿ (Rum Pilot Plant) | El Cinco | |
| 59 | San Antonio Railroad Bridge | San Antonio Railroad Bridge More images | September 30, 2009 (#09000789) | Spanning San Antonio Channel adjacent to Highway 1 at the east end of San Juan Islet 18°27′34″N 66°05′13″W﻿ / ﻿18.459340°N 66.086891°W﻿ / 18.459340; -66.086891﻿ (San Antonio Railroad Bridge) | San Juan Antiguo and Santurce | |
| 60 | San Juan National Historic Site | San Juan National Historic Site More images | October 15, 1966 (#66000930) | Old San Juan 18°28′10″N 66°07′17″W﻿ / ﻿18.469444°N 66.121389°W﻿ / 18.469444; -66.121389﻿ (San Juan National Historic Site) | San Juan Antiguo | Dates from 1525 |
| 61 | School of Tropical Medicine | School of Tropical Medicine More images | September 29, 1983 (#83002297) | Ponce de León Ave., Puerta de Tierra 18°28′01″N 66°06′14″W﻿ / ﻿18.467003°N 66.104005°W﻿ / 18.467003; -66.104005﻿ (School of Tropical Medicine) | San Juan Antiguo | Neo-Plateresque building from 1920 |
| 62 | Superintendent of Lighthouses' Dwelling | Superintendent of Lighthouses' Dwelling More images | October 22, 1981 (#81000694) | Coast Guard Station San Juan, La Puntilla 18°27′36″N 66°07′01″W﻿ / ﻿18.460125°N 66.116874°W﻿ / 18.460125; -66.116874﻿ (Superintendent of Lighthouses' Dwelling) | San Juan Antiguo | Hacienda style building from 1908 located inside the U.S Coast Guard base in La Puntilla |
| 63 | Supreme Court Building | Supreme Court Building More images | June 14, 2006 (#06000506) | Luis Muñoz Rivera Park 18°27′47″N 66°05′18″W﻿ / ﻿18.463189°N 66.088217°W﻿ / 18.463189; -66.088217﻿ (Supreme Court Building) | San Juan Antiguo | Modern Movement building from 1955 |
| 64 | Templo del Maestro | Templo del Maestro | April 19, 2016 (#16000189) | Constitución Ave., Stop 8 18°27′46″N 66°05′24″W﻿ / ﻿18.462777°N 66.089976°W﻿ / 18.462777; -66.089976﻿ (Templo del Maestro) | San Juan Antiguo | |
| 65 | U.S. Custom House | U.S. Custom House More images | February 10, 1988 (#88000075) | 1 Puntilla St. 18°27′46″N 66°06′56″W﻿ / ﻿18.462822°N 66.115522°W﻿ / 18.462822; -66.115522﻿ (U.S. Custom House) | San Juan Antiguo | 1924 building designed by Albert B. Nichols |
| 66 | U.S. Post Office and Courthouse | U.S. Post Office and Courthouse More images | March 28, 1988 (#87000694) | Block bounded by San Justo, Tanca, Commercio, and Recinto Sur Streets 18°27′50″N 66°06′53″W﻿ / ﻿18.463839°N 66.114619°W﻿ / 18.463839; -66.114619﻿ (U.S. Post Office and Courthouse) | San Juan Antiguo | From 1914, designed by Oscar Wenderoth |
| 67 | University of Puerto Rico Tower and Quadrangle | University of Puerto Rico Tower and Quadrangle More images | May 17, 1984 (#84003174) | Ponce de León Ave. 18°24′10″N 66°02′59″W﻿ / ﻿18.402705°N 66.049684°W﻿ / 18.402705; -66.049684﻿ (University of Puerto Rico Tower and Quadrangle) | Universidad | Tower and quadrangle from 1935, designed by Rafael Carmoega |
| 68 | Villa Victoria | Villa Victoria | January 6, 2015 (#14001135) | 905 Ponce de León Ave. 18°27′16″N 66°04′48″W﻿ / ﻿18.454554°N 66.080045°W﻿ / 18.454554; -66.080045﻿ (Villa Victoria) | Santurce | |