# List of museums in New York (state)

This list of museums in New York is a list of museums, defined for this context as institutions (including nonprofit organizations, government entities, and private businesses) that collect and care for objects of cultural, artistic, scientific, or historical interest and make their collections or related exhibits available for public viewing. Museums that exist only in cyberspace (i.e., virtual museums) are not included. Also included are non-profit art centers and galleries.
The following museums are in New York, but their lists are maintained separately:
* List of museums in New York City
* List of museums on Long Island for museums in Nassau and Suffolk counties
* List of university art museums and galleries in New York State
Also, a list of museum ships in New York includes some ships that are museums, plus individual ships within larger museums.

## The list

Museums in New York State besides those in New York City, Long Island, or universities are the following:
| Name | Location | County | Region | Type | Summary |
| 1805 Frisbie House | Salisbury Center | Herkimer | Adirondack Region | Local history | Operated by the Salisbury Historical Society |
| 1812 Homestead Farm and Museum | Willsboro | Essex | Adirondack Region | Agriculture | Recreates daily farm life in the early 19th century |
| 1863 Schoolhouse | Deerpark | Orange | Mid-Hudson | Local history | |
| 1890 House Museum | Cortland | Cortland | Finger Lakes | Historic house | website, focuses on Victorian life |
| Adirondack History Center Museum | Elizabethtown | Essex | Adirondack Region | Local history | website, operated by the Essex County Historical Society |
| Adirondack Lakes Center for the Arts | Blue Mountain Lake | Hamilton | Adirondack Region | Art | website |
| Adirondack Mennonite Heritage Farm | Croghan | Lewis | Adirondack Region | Historic house | Operated by the Adirondack Mennonite Heritage Association & Historical Society, 19th-century house and farm buildings with exhibits about early Amish-Mennonite settlers in the area |
| Adirondack Experience | Blue Mountain Lake | Hamilton | Adirondack Region | Local history | Outdoor recreation, boats and boating, transportation, fine art, work and industry, tourism, and community life |
| Adsit Log Cabin | Willsboro | Essex | Adirondack Region | Historic house | 18th-century log cabin |
| Afton Historical Museum | Afton | Chenango | Central Leatherstocking | Local history | website, operated by the Afton Historical Society |
| Agricultural Memories Museum | Penn Yan | Yates | Finger Lakes | Agriculture | Antique farm tractors, farm equipment, carriages, toy tractors, open by appointment |
| Akin Free Library | Pawling | Dutchess | Mid-Hudson | Multiple | Library with museum of local history operated by the Pawling Historical Society and the Olive Gunnison Natural History Museum |
| Akwesasne Cultural Center | Hogansburg | Franklin | Adirondack Region | Native American | |
| Albany Center Gallery | Albany | Albany | Capital District | Art | Contemporary art |
| Albany Institute of History & Art | Albany | Albany | Capital District | Multiple | Art, local history, founded in 1791 |
| Albany Pine Bush Discovery Center | Albany | Albany | Capital District | Natural history | Natural history of the Albany Pine Bush Preserve |
| Alfred Ceramic Art Museum | Alfred | Allegany | Buffalo Niagara Region | Art | Part of Alfred University, historic and contemporary ceramic and glass objects |
| Alice T. Miner Museum | Chazy | Clinton | Adirondack Region | Historic house | 1824 Colonial Revival house with period furnishings |
| Alling Coverlet Museum | Palmyra | Wayne | Finger Lakes | Textile | website, coverlets date from the 1830s to the 1880s and quilts, operated by Historic Palmyra |
| American Italian Museum & Cultural Center | Albany | Albany | Capital District | Ethnic | website |
| American Maple Museum | Croghan | Lewis | Adirondack Region | Food and drink | website |
| American Museum of Cutlery | Cattaraugus | Cattaraugus | Buffalo Niagara Region | Industry | Examples of knives, swords, edged tools and weapons |
| Ames Museum | Ames | Montgomery | Mohawk Valley | Local history | |
| Anderson Falls Heritage Museum | Keeseville | Essex | Adirondack Region | Local history | Operated by the Anderson Falls Heritage Society |
| Antique Boat Museum | Clayton | Jefferson | Thousand Islands | Maritime | |
| Arcade Historical Society Museum | Arcade | Wyoming | Buffalo Niagara Region | Local history | website, also known as the Gibby House |
| Arkell Museum | Canajoharie | Montgomery | Mohawk Valley | Multiple | American art and history |
| Arnot Art Museum | Elmira | Chemung | Finger Lakes | Art | Includes 17th to 19th-century European paintings, and 19th and 20th-century American art, 21st-century contemporary representational art |
| Art Museum at SUNY Potsdam | Potsdam | St. Lawrence | Thousand Islands | Art | Also known as Gibson Gallery, part of State University of New York at Potsdam |
| Arts Center of Yates County | Penn Yan | Yates | Finger Lakes | Art | website, arts center with exhibit gallery |
| Ashford Historical Society Museum | West Valley | Cattaraugus | Buffalo Niagara Region | Local history | Open by appointment |
| AWA Wireless Museum | Bloomfield | Ontario | Finger Lakes | Technology | website, vintage radio equipment, operated by the Antique Wireless Association |
| Avon Preservation and Historical Society Museum | Avon | Livingston | Finger Lakes | Local history | website |
| Babbie Rural & Farm Learning Museum | Peru | Clinton | Adirondack Region | Agriculture | website, rural farm buildings, equipment and tools |
| Bainbridge Museum | Bainbridge | Chenango | Central Leatherstocking | Local history | photos, operated by the Bainbridge Historical Society |
| Bannerman Castle | Pollepel Island | Dutchess | Mid-Hudson | Historic house | Tours of the early 20th-century castle house, part in ruins, accessible by boat |
| Barker Historical Museum | Fredonia | Chautauqua | Buffalo Niagara Region | Local history | |
| Bedford Museum | Bedford | Westchester | Lower Hudson | Local history | website Archived 2010-08-04 at the Wayback Machine, operated by the Bedford Historical Society, includes the restored 1787 Court House and local history exhibits, also operates the 1829 School House |
| Bement-Billings Farmstead | Newark Valley | Tioga | Finger Lakes | Historic house | Operated by the Newark Valley Historical Society, early 19th-century period house and farmstead, costumed docents with craft demonstrations |
| Bemus Point Historical Museum | Bemus Point | Chautauqua | Buffalo Niagara Region | Local history | Operated by the Bemus Point Historical Society |
| Benjamin and Dr. Edgar R. Codeld Judaic Museum | Buffalo | Erie | Buffalo Niagara Region | Judaica | Located in Temple Beth Zion, features over 1,000 Judaic artifacts dating from the 10th century, also known as the Codeld Judaic Museum |
| Benjamin Long Homestead | Tonawanda | Niagara | Buffalo Niagara Region | Historic house | website, operated by the Historical Society of the Tonawandas, 19th-century house |
| Benjamin Patterson Inn | Corning | Steuben | Finger Lakes | Open air | Operated by the Corning-Painted Post Historical Society, complex includes Benjamin Patterson Inn, Wixson Road Log Cabin, Blacksmith Shop, Starr Barn, Browntown Schoolhouse |
| Best House and Medical Exhibit | Middleburgh | Schoharie | Capital District | Historic house | Former country doctor's home with medical exhibits, life from the 1870s to 1940s |
| Beth Joseph Synagogue | Tupper Lake | Franklin | Adirondack Region | Judaica | |
| Bevier House Museum | Marbletown | Ulster | Mid-Hudson | Historic house | Home of the Ulster County Historical Society, stone house dating from the 17th century |
| Big Flats Historical Society Museum | Big Flats | Chemung | Finger Lakes | Local history | website |
| Big Springs Museum | Caledonia | Livingston | Finger Lakes | Local history | website, operated by the Big Springs Historical Society |
| Binghamton University Art Museum | Binghamton | Broome | Central Leatherstocking | Art | Part of Binghamton University |
| Blenheim-Gilboa Visitors Center | North Blenheim | Schoharie | Capital District | Science | Energy and electricity |
| Blockhouse Museum & Historic Park | Brewerton | Oswego | Central New York | Local history | Operated by the Fort Brewerton Historical Society, reconstruction of a late 18th-century log block house |
| Bluff Point Lighthouse | Valcour Island | Clinton | Adirondack Region | Lighthouse | Operated by the Clinton County Historical Association, exhibits about the lighthouse and local history and natural history |
| Boldt Castle | Alexandria Bay | Jefferson | Thousand Islands | Historic house | Early 20th-century castle house |
| Bolton Historical Museum | Bolton Landing | Warren | Adirondack Region | Local history | website, operated by the Historical Society of the Town of Bolton |
| Book of Mormon Historic Publication Site | Palmyra | Wayne | Finger Lakes | Religious | Historic print shop of E. B. Grandin, first publisher of the Book of Mormon |
| Boonville Black River Canal Museum | Boonville | Oneida | Adirondack Region | Canals | website, history of the Black River Canal |
| Boscobel | Cold Spring | Putnam | Lower Hudson | Historic house | 19th-century mansion and estate |
| Brain Museum | Buffalo | Erie | Buffalo Niagara Region | Medical | website, also known as the Museum of Neuroanatomy, collection of brain specimens, part of University at Buffalo School of Medicine and Biomedical Sciences |
| Brick Church Museum | Galen | Wayne | Finger Lakes | Local history | website, operated by the Galen Historical Society |
| Brick Tavern Stand | Montour Falls | Schuyler | Finger Lakes | Local history | Operated by the Schuyler County Historical Society |
| Bridge House Museum | Phoenix | Oswego | Central New York | Local history | website |
| Bronck House | Coxsackie | Greene | Capital District | Historic house | 17th-century Dutch homestead, operated by the Greene County Historical Society |
| Brookfield Museum | Brookfield | Madison | Central Leatherstocking | Local history | website, operated by the Town of Brookfield Historical Society |
| Brookside Museum | Ballston Spa | Saratoga | Adirondack Region | Local history | Home of the Saratoga County Historical Society |
| Buffalo AKG Art Museum | Buffalo | Erie | Buffalo Niagara Region | Art | Modern and contemporary art; formerly known as the Buffalo Albright-Knox Gallery |
| Buffalo and Erie County Naval & Military Park | Buffalo | Erie | Buffalo Niagara Region | Maritime | Home to several decommissioned US Naval vessels including the Cleveland-class cruiser USS Little Rock, the Fletcher-class destroyer USS The Sullivans, and the submarine USS Croaker |
| Buffalo Fire Historical Museum | Buffalo | Erie | Buffalo Niagara Region | Firefighting | |
| Buffalo Harbor Museum | Buffalo | Erie | Buffalo Niagara Region | Maritime | website, operated by the Lower Lakes Marine Historical Society, history of the Port of Buffalo, its harbor, waterways and their role in the development of the economies of the Niagara Frontier |
| Buffalo History Museum | Buffalo | Erie | Buffalo Niagara Region | Local history | Local history, industry, Native Americans, pioneers, ethnic heritage and culture, 19th-century shops and businesses |
| Buffalo Motorcycle Museum | Buffalo | Erie | Buffalo Niagara Region | Transportation - Motorcycle | website Archived 2008-05-11 at the Wayback Machine |
| Buffalo Museum of Science | Buffalo | Erie | Buffalo Niagara Region | Science | Themes include science, animals, astronomy, the science of technology, health |
| Buffalo Niagara Heritage Village | Amherst | Erie | Buffalo Niagara Region | Open air | 12 historic buildings including homes, one-room schoolhouses, a barbershop, and a church, formerly the Amherst Museum |
| Buffalo, Rochester and Pittsburgh Railway Station | Orchard Park | Erie | Buffalo Niagara Region | Railroad | Operated by the Western New York Railway Historical Society |
| Buffalo Transportation Pierce-Arrow Museum | Buffalo | Erie | Buffalo Niagara Region | Transportation | website, Pierce-Arrow cars, motorcycles, bicycles and memorabilia |
| Bull Stone House | Hamptonburgh | Orange | Mid-Hudson | Historic house | Early 18th-century stone house |
| Bullthistle Model Railroad Society Museum | Norwich | Chenango | Central Leatherstocking | Railroad | website, model railroad layouts |
| Bundy Museum of History and Art | Binghamton | Broome | Central Leatherstocking | Multiple | Victorian period house, Bundy Manufacturing Company time recorder clocks and artifacts, modern & African art, local history, Southern Tier Broadcasters Hall of Fame, period barber shop |
| Burchfield-Penney Art Center | Buffalo | Erie | Buffalo Niagara Region | Art | Features works by Charles E. Burchfield, J. J. Lankes and other area artists |
| Burden Iron Works | Troy | Rensselaer | Capital District | Industry - Iron | Open by appointment only |
| Busti Grist Mill & Historical Society Museum | Busti | Chautauqua | Buffalo Niagara Region | Mill | Open for annual fall festival and by appointment |
| Butler Church Museum | Butler | Wayne | Finger Lakes | Local history | Operated by the Butler Historical Society |
| Call Homestead Museum | Andover | Allegany | Buffalo Niagara Region | History | 19th- and 20th-century farm equipment and traditional rural implements, butter churns, crocks, clocks, quilts, toys, musical instruments, furniture, artwork and local pottery |
| Cambridge Historical Society Museum | Cambridge | Washington | Adirondack Region | Local history | website, Victorian house with period furnishings and local history displays |
| Camp Santanoni | Newcomb | Essex | Adirondack Region | Historic camp | National Historic Landmark camp open for tours |
| Camp Shanks World War II Museum | Orangeburg | Rockland | Lower Hudson | Military | Former embarkation point for troops in World War II |
| Canal Town Museum | Canastota | Madison | Central Leatherstocking | Local history | |
| Carnegie Art Center | North Tonawanda | Niagara | Buffalo Niagara Region | Art | Contemporary art exhibits, visual art and dance classes |
| Caroga Historical Museum | Caroga | Fulton | Adirondack Region | Open-air | website, farm house, exhibit barn, general store, cobbler's shop, ice house and Sherman's Park Arcade, operated by the Caroga Historical Association |
| Carriage House Museum | Camden | Oneida | Central Leatherstocking | Local history | information |
| Cary Hill Sculpture Park | Salem | Washington | Adirondack Region | Sculpture park | |
| CAS Arts Center | Livingston Manor | Sullivan | Mid-Hudson | Art | website, operated by the Catskill Art Society |
| Casey's Cottage | Mexico | Oswego | Thousand Islands | Local history | website Archived 2014-07-16 at the Wayback Machine, located in Mexico Point State Park, medieval-style cottage |
| Casparus F. Pruyn House | Newtonville | Albany | Capital District | Historic house | 19th-century Greek Revival house, restored one-room schoolhouse, smokehouse, potting shed, woodshed/privy building, carriage house, well house, gardens, historic and cultural arts programs |
| Castellani Art Museum | Lewiston | Niagara | Buffalo Niagara Region | Art | Contemporary art and folk art, part of Niagara University |
| Castile Historical Museum | Castile | Wyoming | Buffalo Niagara Region | Local history | website, operated by the Castile Historical Society |
| Catamount People's Museum | Catskill | Greene | Capital District | Culture | website, people, stories, culture and history of the Catskill Mountains, located in a bobcat-shaped building built out of salvaged wood |
| Cattaraugus County Museum | Machias | Cattaraugus | Buffalo Niagara Region | Local history | website, also known as the Stone House |
| Catskill Fly Fishing Center and Museum | Livingston Manor | Sullivan | Mid-Hudson | Sports | |
| Caverns Creek Grist Mill | Howes Cave | Schoharie | Capital District | Mill | Mill museum and country store |
| Cayuga Museum of History and Art | Auburn | Cayuga | Finger Lakes | Multiple | Local history, art, culture and the invention of sound film |
| Central Square Museum | Central Square | Oswego | Thousand Islands | Railroad | website Archived 2008-08-28 at the Wayback Machine, operated by the Central New York Chapter, National Railway Historical Society |
| Center for Photography at Woodstock | Kingston, New York | Ulster | Mid-Hudson | Art | website, Artist-centered contemporary photography organization with exhibits |
| CEPA Gallery | Buffalo | Erie | Buffalo Niagara Region | Art | website, contemporary photography and visual arts center |
| Champlain Valley Transportation Museum | Plattsburgh | Clinton | Adirondack Region | Transportation | Includes cars, canoes, trains, trolleys and more |
| Chapman Historical Museum | Glens Falls | Warren | Adirondack Region | Historic house | Late 19th-century period house |
| Charles Dickert Wildlife Collection | Saranac Lake | Franklin | Adirondack Region | Natural history | website, located on the first floor of the Saranac Lake Free Library, taxidermy specimens of local animals |
| Charlotte-Genesee Lighthouse | Rochester | Monroe | Finger Lakes | Lighthouse | Operated by the Charlotte-Genesee Lighthouse Historical Society |
| Charlton Historical Society Museum | Charlton | Saratoga | Adirondack Region | Local history | website |
| Chautauqua Institution | Chautauqua | Chautauqua | Buffalo Niagara Region | Art | Visual arts gallery, performing arts |
| Cheektowaga Historical Museum | Cheektowaga | Erie | Buffalo Niagara Region | Local history | Operated by the Cheektowaga Historical Association |
| Chemung Valley History Museum | Elmira | Chemung | Finger Lakes | Local history | Operated by the Chemung County Historical Society |
| Chenango Canal Cottage Museum | Bouckville | Madison | Central Leatherstocking | Canals | website, operated by the Chenango Canal Association |
| Chenango County Historical Society | Norwich | Chenango | Central Leatherstocking | Local history | website |
| Cherry Valley Museum | Cherry Valley | Otsego | Central Leatherstocking | Local history | website |
| Children's Museum at Saratoga | Saratoga Springs | Saratoga | Capital District | Children's | website |
| Children's Museum of Oswego | Oswego | Oswego | Thousand Islands | Children's | website |
| Children's Museum of Science and Technology | Troy | Rensselaer | Capital District | Science | |
| Chittenango Landing Canal Boat Museum | Chittenango | Madison | Central Leatherstocking | Canals | Open seasonally, construction and repair of canal boats and the social history of the Erie Canal era |
| Cigarville Railroad Station Museum | Clay | Onondaga | Central New York | Local history | Operated by the Town of Clay Historical Association in Clay Historic Park |
| Clarence Historical Museum | Clarence | Erie | Buffalo Niagara Region | Local history | website, operated by the Clarence Historical Society |
| Clermont State Historic Site | Clermont | Columbia | Capital District | Historic house | 1930s period manor house and estate with exhibits about the Livingston family |
| Clifton F. West Historical Museum | Hague | Warren | Adirondack Region | Local history | website, operated by the Hague Historical Society |
| Clinton County Historical Museum | Plattsburgh | Clinton | Adirondack Region | Local history | website, operated by the Clinton County Historical Association |
| Clove Furnace Historic Site | Arden | Orange | Mid-Hudson | Industry - Iron | Iron blast furnace ruins and museum |
| Cobblestone Society Museum | Childs | Orleans | Buffalo Niagara Region | Local history | 1834 church, 1840 house and 1849 house that exemplify area cobblestone architecture |
| Columbia County Museum | Kinderhook | Columbia | Capital District | Local history | Operated by the Columbia County Historical Society, includes the Luykas Van Alen House, 1850 Ichabod Crane Schoolhouse, 1819 James Vanderpoel House |
| Colton Museum | Colton | St. Lawrence | Thousand Islands | Local history | website Archived 2016-01-29 at the Wayback Machine, open daily 10-2 and by appointment with the Colton Historical Society |
| Constitution Island | West Point | Orange | Mid-Hudson | Historic house - Fort | Tour includes boat ride to and from island, guided tour of Revolutionary War fortifications and 17-room Warner House |
| Cook Museum of Local History | Galway | Saratoga | Adirondack Region | Local history | Restored Victorian house with Victorian rooms, dolls, clothing, dishes, tools, bibles |
| Corinth Museum | Corinth | Saratoga | Adirondack Region | Local history | website |
| Cornerstone Park | Carmel | Putnam | Lower Hudson | Local history | website |
| Corning Museum of Glass | Corning | Steuben | Finger Lakes | Industry - Glass | |
| Cottage Lawn Museum | Oneida | Madison | Central Leatherstocking | Historic house | Operated by the Madison County Historical Society, Victorian period house and local history displays |
| Crandall Public Library Folklife Center | Glens Falls | Warren | Adirondack Region | Multiple | website Archived 2010-09-19 at the Wayback Machine, exhibits of the history and culture of the upper Hudson Valley and southern Adirondacks of upstate New York |
| Czurles-Nelson Gallery | Buffalo | Erie | Buffalo Niagara Region | Art | website, part of Buffalo State University |
| Cropsey Homestead | Hastings-on-Hudson | Westchester | Lower Hudson | Art | Also known as Ever Rest, studio with artwork of Jasper F. Cropsey, operated by the Newington-Cropsey Foundation along with their Gallery of Art, featuring works by Cropsey |
| Crown Point State Historic Site | Crown Point | Essex | Adirondack Region | Military | Remains of a Colonial era fort and museum |
| Cuba Cheese Museum | Cuba | Allegany | Buffalo Niagara Region | Food and drink | |
| Cuba Historical Society Museum | Cuba | Allegany | Buffalo Niagara Region | Local history | |
| Daniel Parrish Witter Agricultural Museum | Syracuse | Onondaga | Central New York | Agriculture | website, open during the New York State Fair, farming tools, equipment, log cabin, demonstrations, operated by the NYS Agricultural Society |
| Dansville Area Historical Museum | Dansville | Livingston | Finger Lakes | Local history | website Archived 2016-03-13 at the Wayback Machine, operated by the Dansville Area Historical Society |
| Dart Airport Aviation Museum | Mayville | Chautauqua | Buffalo Niagara Region | Aviation | |
| Darwin D. Martin House | Buffalo | Erie | Buffalo Niagara Region | Historic house | Designed by Frank Lloyd Wright |
| Das Haus und Der Stahl | Niagara Falls | Niagara | Buffalo Niagara Region | Ethnic | Area German heritage museum in an 1843 home of original settlers |
| David Crawford House | Newburgh | Orange | Mid-Hudson | Historic house | Operated by the Historical Society of Newburgh Bay and the Highlands |
| David Sayre Store and House Museum | Milford | Otsego | Central Leatherstocking | History | Facebook site, early 19th-century period store operated by the Greater Milford Historical Association |
| Dayton Historical Museum | Dayton | Cattaraugus | Buffalo Niagara Region | Local history | |
| Dayton's Corners School | Penfield | Monroe | Finger Lakes | Education | Open during special events; one-room schoolhouse |
| De Kalb Historical Association Museum | De Kalb | St. Lawrence | Thousand Islands | Local history | |
| Delaware and Hudson Canal Museum | High Falls | Ulster | Mid-Hudson | Canals | History of the Delaware & Hudson Canal, operated by the D & H Canal Historical Society |
| Deposit Historical Society Museum | Deposit | Delaware | Central Leatherstocking | Local history | website |
| DeRuyter Museum | DeRuyter | Madison | Central Leatherstocking | Local history | Operated by the Tromptown Historical Society |
| DeWint House | Tappan | Rockland | Lower Hudson | Historic house | 18th-century Colonial Dutch house, temporary headquarters of Commander-in-Chief George Washington during the American Revolution |
| Dia Beacon | Beacon | Dutchess | Mid-Hudson | Art | one of the twelve locations and sites the Dia Art Foundation manages. |
| DIRT Museum & Hall of Fame | Weedsport | Cayuga | Finger Lakes | Automotive | website, classic cars, stock cars, memorabilia and a drivers' hall of fame |
| Discovery Center of the Southern Tier | Binghamton | Broome | Central Leatherstocking | Children's | website |
| Donald M. Kendall Sculpture Gardens | Purchase | Westchester | Lower Hudson | Sculpture park | Collection of 45 pieces of outdoor sculpture at the Pepsico world headquarters |
| Dowd Gallery | Cortland | Cortland | Finger Lakes | Art | website, part of State University of New York at Cortland |
| Dr. John Quincy Howe House | Phelps | Ontario | Finger Lakes | Local history | Operated as a museum of local history by the Phelps Community Historical Society |
| Dunkirk Lighthouse & Veterans Museum | Dunkirk | Chautauqua | Buffalo Niagara Region | Military | Lighthouse and keeper's cottage with collection of military artifacts |
| Dunkirk Historical Museum | Dunkirk | Chautauqua | Buffalo Niagara Region | Local history | website, local history, art and culture, includes Brooks Locomotive Works equipment and artifacts |
| Durham Center Museum | East Durham | Greene | Capital District | Local history | |
| Dyke Museum | Wellsville | Allegany | Buffalo Niagara Region | Local history | Operated by The Thelma Rogers Genealogical & Historical Society |
| East Bloomfield Historical Society | East Bloomfield | Ontario | Finger Lakes | Local history | website |
| East Otto Historical Museum | East Otto | Cattaraugus | Buffalo Niagara Region | Local history | |
| Edith Langley Barrett Fine Art Gallery | Utica | Oneida | Adirondack Region | Art | website, part of Utica University |
| Edmonston House | New Windsor | Orange | Mid-Hudson | Historic house | 18th-century period house |
| Edward Hopper House Art Center | Nyack | Rockland | Lower Hudson | Art | |
| Edwin Welling Van Duzer Memorial House | Middletown | Orange | Mid-Hudson | Historic house | Facebook site, home of the Historical Society of Middletown & the Wallkill Precinct |
| El Museo Francisco Oller y Diego Rivera | Buffalo | Erie | Buffalo Niagara Region | Art | website, exhibition of fine art by Latin/Caribbean, African-American and other artists of color |
| Elbert Hubbard Roycroft Museum | East Aurora | Erie | Buffalo Niagara Region | Historic house | Arts and Crafts movement style home featuring furniture and decorative items produced by the Roycroft community, located in the George and Gladys Scheidemantel House |
| Eleanor Roosevelt National Historic Site | Hyde Park | Dutchess | Mid-Hudson | Historic house | |
| Eleazer Harding House | Otisville | Orange | Mid-Hudson | Historic house | information, operated by Mount Hope Historical Society |
| Elijah Miller House | White Plains | Westchester | Lower Hudson | Historic house | 18th-century farmhouse used during the Revolutionary War by General George Washington as a headquarters command post during the Battle of White Plains |
| Elizabeth Cady Stanton House | Seneca Falls | Seneca | Finger Lakes | Historic house | Part of Women's Rights National Historical Park |
| Ellenville Public Library and Museum | Ellenville | Ulster | Mid-Hudson | Local history | website, known as the Terwilliger House Museum |
| Ellicottville Historical Museum | Ellicottville | Cattaraugus | Buffalo Niagara Region | Local history | Open seasonally |
| Elma Historical Society Museum | Elma | Erie | Buffalo Niagara Region | Local history | website, local history, also 1847 water-powered saw mill |
| Empire State Aerosciences Museum | Glenville | Schenectady | Capital District | Aviation | |
| Empire State Heritage Park | Rome | Oneida | Central New York | Canals | website, formerly Erie Canal Village, area canal heritage |
| Empire State Railway Museum | Phoenicia | Ulster | Mid-Hudson | Railroad | |
| Empire State Theater Musical Instrument Museum | Syracuse | Onondaga | Central New York | Music | website, located in the Empire Expo Center and open during the New York State Fair, theater organs |
| Endicott Visitor Center | Endicott | Broome | Central Leatherstocking | Local history | website Archived 2015-02-14 at the Wayback Machine, includes a museum of local history |
| Erie Canal Discovery Center | Lockport | Niagara | Buffalo Niagara Region | Canals | website, operated by the Niagara County Historical Society, construction and operations of the Erie Canal |
| Erie Canal Depot | Palmyra | Wayne | Finger Lakes | Local history | , history of the Erie Canal in the depot at Historic Palmyra |
| Erie Canal Museum | Syracuse | Onondaga | Central New York | Canals | History of the Erie Canal |
| Erie Canal Park | Camillus | Onondaga | Finger Lakes | History | website, includes Sims' Store Museum, replica of the original Sims' canal store, and a steam engine exhibit |
| Esperance Historical Museum | Esperance | Schoharie | Capital District | Local history | Facebook site, operated by the Esperance Historical Society |
| Everson Museum of Art | Syracuse | Onondaga | Central New York | Art | American art |
| Explore & More Children's Museum | East Aurora | Erie | Buffalo Niagara Region | Children's | |
| Fannie Bartlett House/Olean Point Museum | Olean | Cattaraugus | Buffalo Niagara Region | Local history | information, information |
| Farmers' Museum | Cooperstown | Otsego | Central Leatherstocking | Agriculture | Living farm museum, also home to the Empire State Carousel |
| FASNY Museum of Firefighting | Hudson | Columbia | Capital District | Firefighting | website, heritage of firefighting in New York State |
| Fenimore Art Museum | Cooperstown | Otsego | Central Leatherstocking | Art | American Folk, North American Indian, Hudson River School and 19th-century genre art and American photography |
| Fenton History Center | Jamestown | Chautauqua | Buffalo Niagara Region | Local history | |
| Fiddlers Hall of Fame and Museum | Redfield | Oswego | Adirondack Region | Music | website, operated by the New York State Old Tyme Fiddlers' Association |
| Finger Lakes Boating Museum | Penn Yan | Yates | Finger Lakes | Maritime | website, over 60 Finger-Lakes-built boats |
| Fire Museum of Syracuse | Syracuse | Onondaga | Central New York | Firefighting | Open by appointment only |
| Fleischmanns Museum of Memories | Fleischmanns | Delaware | Central Leatherstocking | Local history | Located behind the Skene Memorial Library and open from Memorial Day through Labor Day |
| Fort Crailo | Rensselaer | Rensselaer | Capital District | Historic house | Colonial New Netherland history, also known as Crailo State Historic Site |
| Fort Decker Museum of History | Port Jervis | Orange | Mid-Hudson | Historic house | Operated as a local history museum by the Minisink Valley Historical Society |
| Fort Delaware Museum | Narrowsburg | Sullivan | Mid-Hudson | Open air | website, depiction of the life of pioneers who settled in the Upper Delaware Valley in 1754 |
| Fort Drum Museum | Fort Drum | Jefferson | Thousand Islands | Military | website Archived 2014-09-29 at the Wayback Machine, history of the 10th Mountain Division and Fort Drum, Facebook site |
| Fort Klock | St. Johnsville | Montgomery | Mohawk Valley | Open air | Revolutionary era historic homestead, Colonial Dutch Barn, blacksmith shop, and 19th-century schoolhouse |
| Fort Montgomery State Historic Site | Fort Montgomery | Orange | Mid-Hudson | Military | American Revolutionary War site and museum |
| Fort Ontario | Oswego | Oswego | Adirondack Region | Military | Star-shaped fort restored to its 1868-1872 appearance |
| Fort Plain Museum & Historical Park | Fort Plain | Montgomery | Central Leatherstocking | History | website, Revolutionary War headquarters of Marinus Willett |
| Fort Stanwix National Monument | Rome | Oneida | Adirondack Region | Military | Reconstructed Colonial fort, important site during the American Revolutionary War, living history enactments |
| Fort Ticonderoga | Ticonderoga | Essex | Adirondack Region | Military | Revolutionary fort with costumed interpreters represent 18th-century soldiers and refugee women |
| Fort William Henry | Lake George | Warren | Adirondack Region | Military | French & Indian War fort with costumed interpreters |
| Fosdick-Nelson Gallery | Alfred | Allegany | Buffalo Niagara Region | Art | website, part of Alfred University, contemporary art |
| Foster Cottage Museum | Clifton Springs | Ontario | Finger Lakes | Historic house | website, operated by the Clifton Springs Historical Society |
| Foster Farm Museum | Brewster | Putnam | Lower Hudson | Agriculture | Historic farm featuring rare and endangered early American farm animals, farm equipment, rock and roll memorabilia |
| Frances Lehman Loeb Art Center | Poughkeepsie | Dutchess | Mid-Hudson | Art | Part of Vassar College |
| Franklin D. Roosevelt Presidential Library and Museum | Hyde Park | Dutchess | Mid-Hudson | Biographical | |
| Franklin House of History | Malone | Franklin | Adirondack Region | Historic house | website, operated by the Franklin County Historical and Museum Society |
| Frederic Remington Art Museum | Ogdensburg | St. Lawrence | Thousand Islands | Art | Works of Frederic Remington |
| Fred J. Johnston Museum | Kingston | Ulster | Mid-Hudson | Historic house | website, operated by Friends of Historic Kingston, 1812 house with collection of 18th and early 19th century furnishings and decorative arts |
| Friends of Historic Kingston Museum | Kingston | Ulster | Mid-Hudson | Local history | website, operated by Friends of Historic Kingston |
| Frisbee House and Museum | Delhi | Delaware | Central Leatherstocking | Open air | Operated by the Delaware County Historical Association, home to 7 historic buildings including the 1797 Frisbee House |
| Frontenac Museum | Union Springs | Cayuga | Finger Lakes | Local history | website, operated by the Frontenac Historical Society |
| Fryer Memorial Museum | Munnsville | Madison | Central Leatherstocking | Local history | website |
| Fulton County Museum | Gloversville | Fulton | Adirondack Region | Local history | website, operated by the Fulton County Historical Society |
| Ganondagan State Historic Site | Victor | Ontario | Finger Lakes | Native American | Seneca village |
| Gates House Museum | Warsaw | Wyoming | Buffalo Niagara Region | Local history | Operated by the Warsaw Historical Society, 19th-century house |
| Gateway Museum | Morristown | St. Lawrence | Thousand Islands | History | website, local history, culture |
| General Richard Montgomery House | Rhinebeck | Dutchess | Mid-Hudson | Historic house | website Archived 2009-08-31 at the Wayback Machine, occupied by General Richard Montgomery during the American Revolutionary War, open by appointment with the Chancellor Livingston Chapter, NSDAR |
| Genesee Country Village and Museum | Mumford | Monroe | Finger Lakes | Open air | 19th-century living history museum, includes John L. Wehle Gallery of Sporting Art, Genesee Country Nature Center, Carriage Museum, Silver Baseball Park and Heirloom Gardens |
| Geneva History Museum | Geneva | Ontario | Finger Lakes | Local history | website, located in the Prouty-Chew House, operated by the Geneva Historical Society |
| George Barton House | Buffalo | Erie | Buffalo Niagara Region | Historic house | Designed by Frank Lloyd Wright |
| George Eastman Museum | Rochester | Monroe | Finger Lakes | Photography | Historic mansion with exhibits on photography and film |
| Georgetown Historical Society Museum | Georgetown | Madison | Central Leatherstocking | Local history | |
| Georgi on the Battenkill Museum and Park | Shushan | Washington | Adirondack Region | Art | website, Italian, Dutch, Flemish, German and French paintings from the 14th through the 18th centuries, Chinese and Asian tapestries and figurines |
| Gerrit Smith Estate | Peterboro | Madison | Finger Lakes | Historic house | 19th-century house, site along the Underground Railroad |
| Gilboa Museum | Gilboa | Schoharie | Mohawk Valley | Local history | website, fossils, local history, operated by the Gilboa Historical Society |
| Glebe House | Poughkeepsie | Dutchess | Mid-Hudson | Historic house | 18th-century period house |
| Glenn H. Curtiss Museum | Hammondsport | Steuben | Finger Lakes | Aviation | Early aviation and local history |
| Gomez Mill House | Newburgh | Orange | Mid-Hudson | Historic house | Earliest surviving Jewish residence in North America |
| Goodsell Museum | Old Forge | Herkimer | Adirondack Region | Local history | Operated by the Town of Webb Historical Association |
| Gouverneur Museum | Gouverneur | St. Lawrence | Thousand Islands | Local history | website |
| Granger Homestead and Carriage Museum | Canandaigua | Ontario | Finger Lakes | Historic house | 19th-century period mansion, collection of carriages |
| Grant Cottage State Historic Site | Wilton | Saratoga | Capital District | Historic house | Late 19th-century period house where President Ulysses S. Grant died in 1885 |
| Graycliff | Derby | Erie | Buffalo Niagara Region | Historic house | Designed by Frank Lloyd Wright |
| Great Camp Sagamore | Raquette Lake | Hamilton | Adirondack Region | Historic camp | National Historic Landmark camp open for tours |
| Greater Oneonta Historical Society History Center | Oneonta | Otsego | Central Leatherstocking | Local history | website |
| Greece Museum | Greece | Monroe | Finger Lakes | Local history | website, operated by the Greece Historical Society |
| Greenfield Park Museum | Wawarsing | Ulster | Mid-Hudson | Education | One-room schoolhouse |
| Griffis International Sculpture Garden | Rome | Oneida | Central New York | Art | website, outdoor art park, works created by Sculpture Space in Griffiss Business and Technology Park |
| Griffis Sculpture Park | East Otto | Cattaraugus | Buffalo Niagara Region | Sculpture park | 425-acre (1.72 km$^2$) outdoor art museum |
| Groton Historical Association Museum | Groton | Tompkins | Finger Lakes | Local history | |
| H.P. Sears Oil Co. Service Station Museum | Rome | Oneida | Central New York | Automotive | website, restored service station with automotive memorabilia |
| Hagadorn House | Almond | Allegany | Buffalo Niagara Region | Historic house | website, operated by the Almond Historical Society |
| Half-Shire Historical Society Museum | Richland | Oswego | Adirondack Region | Local history | website |
| Hallwalls Contemporary Arts Center | Buffalo | Erie | Buffalo Niagara Region | Art | Showcases artists of diverse backgrounds in film, video, literature, music, performance, media and visual arts |
| Hamilton Hill Arts Center | Schenectady | Schenectady | Capital District | Art | website, African and African American art and culture |
| Hamlin's North Star History Center | Hamlin | Monroe | Finger Lakes | Local history | |
| Hammond Historical Museum | Hammond | St. Lawrence | Thousand Islands | Local history | website, operated by the R.T. Elethorp Historical Society |
| Hammond Museum and Japanese Stroll Garden | North Salem | Westchester | Lower Hudson | Art | East Asian art and culture and Japanese garden |
| Hancock House Museum | Ticonderoga | Essex | Adirondack Region | Local history | Operated by the Ticonderoga Historical Society |
| Handwerker Gallery | Ithaca | Tompkins | Finger Lakes | Art | website, part of Ithaca College |
| Hanford Mills Museum | East Meredith | Delaware | Central Leatherstocking | Mill | Sawmill, gristmill, feed mill, woodworking shop and hardware store |
| Harmony Historical Society | Blockville | Chautauqua | Buffalo Niagara Region | Local history | website |
| Harness Racing Museum & Hall of Fame | Goshen | Orange | Mid-Hudson | Sports | |
| Harriet Tubman Home | Auburn | Cayuga | Finger Lakes | Biographical | Place where Harriet Tubman spent her last years |
| Hart-Cluett Mansion | Troy | Rensselaer | Capital District | Historic house | Operated by the Rensselaer County Historical Society, 19th-century period rowhouse |
| Hartford Museum & Howard Hanna Memorial Civil War Enlistment Center | Hartford | Washington | Adirondack Region | Local history | Museum located in the Elisha Straight House; depicts life and local industry in the 19th century; center depicts the history of the area men who enlisted for the American Civil War |
| Hastings Historical Society | Hastings-on-Hudson | Westchester | Lower Hudson | Local history | website |
| Haverstraw Brick Museum | Haverstraw | Rockland | Lower Hudson | Industry | website, area brick making industry |
| Hawkins Point Visitors Center | Massena | St. Lawrence | Thousand Islands | Science | website, operated by the New York Power Authority at the St. Lawrence-FDR Power Project, exhibits about energy, electricity and the North Country |
| Heart's Delight Farm | Chazy | Clinton | Adirondack Region | Agriculture | Operated by the Miner Institute, farm history and demonstrations, life of founder William Miner and his railroad inventions |
| Henderson Historical Society and Museum | Henderson | Jefferson | Thousand Islands | Local history | website |
| Herbert F. Johnson Museum of Art | Ithaca | Tompkins | Finger Lakes | Art | Part of Cornell University |
| Heritage Discovery Center Buffalo | Buffalo | Erie | Buffalo Niagara Region | Industry | website, railway, steel and industrial heritage of Western New York, includes the Steel Plant Museum, Western New York Railway Historical Society and other organizations |
| Heritage Museum on the Hemlock Fairgrounds | Hemlock | Livingston | Finger Lakes | History | website, open during the fair and by appointment |
| Heritage Square Museum | Ontario | Wayne | Finger Lakes | Open air | Buildings from the mid-19th century |
| Herkimer County Historical Society Suiter Building Museum | Herkimer | Herkimer | Adirondack Region | Local history | |
| Herkimer County Jail | Herkimer | Herkimer | Adirondack Region | Prison | Tours given by the Herkimer County Historical Society |
| Herkimer Diamond Mines Museum | Herkimer | Herkimer | Adirondack Region | Natural history | website, includes the Herkimer Diamond Mines Gift Shop, Museum, and Prospecting Area, includes exhibits of minerals and fossils |
| Herkimer Home State Historic Site | Danube | Herkimer | Adirondack Region | Historic house | 18th-century period house |
| Heroes of Baseball Wax Museum | Cooperstown | Otsego | Central Leatherstocking | Sport | website |
| Herschell Carrousel Factory Museum | North Tonawanda | Niagara | Buffalo Niagara Region | Carrousel | Housed in an original carousel factory building |
| Hervey Ely House | Rochester | Monroe | Finger Lakes | Historic house | 19th-century mansion, operated by the Irondequoit chapter of the Daughters of the American Revolution |
| Hessel Museum of Art | Annandale-on-Hudson | Dutchess | Mid-Hudson | Art | Part of Bard College, contemporary art |
| High Falls Interpretive Center and Museum | Rochester | Monroe | Finger Lakes | Local history | website, local history, industry, culture, art, operated by the Office of the City Historian |
| Hill-Hold Museum | Hamptonburgh | Orange | Mid-Hudson | Historic house | Hudson Valley farm in the 1830s |
| Historic Cherry Hill | Albany | Albany | Capital District | Historic house | 17th-century house reflecting owners through the 19th century |
| Historic Huguenot Street | Gardiner | Ulster | Mid-Hudson | Open air | Tours of historic houses, including Locust Lawn Estate, operated by the Huguenot Historical Society |
| Historic Pittsford Museum | Pittsford | Monroe | Finger Lakes | Local history | website |
| Historical Society of Rockland County History Center Museum | New City | Rockland | Lower Hudson | Local history | website |
| The Historical Society and Museum | Tarrytown | Westchester | Lower Hudson | Local history | website, history of Tarrytown and Sleepy Hollow, located in the Jacob Odell House |
| The History Center in Tompkins County | Ithaca | Tompkins | Finger Lakes | History | website |
| History House | Moravia | Cayuga | Finger Lakes | Local history | website, operated by the Cayuga-Owasco Lakes Historical Society |
| H. Lee White Marine Museum | Oswego | Oswego | Adirondack Region | Maritime | Boats, ship models, sailmakers' tools, navigational equipment, nautically themed painting, nautical artifacts; home of the World War II-era tugboat Nash |
| Hobart Historical Center | Hobart | Delaware | Central Leatherstocking | Local history | |
| Hoffman Clock Museum | Newark | Wayne | Finger Lakes | Horology | website, history of timekeeping, includes over 300 clocks, watches and tools |
| Holland Land Office Museum | Batavia | Genesee | Buffalo Niagara Region | Local history | History of the Holland Land Company |
| Holocaust Museum & Center for Tolerance and Education | Suffern | Rockland | Lower Hudson | History | website, located at Rockland Community College |
| Home of Franklin D. Roosevelt National Historic Site | Hyde Park | Dutchess | Mid-Hudson | Historic house | |
| Hopkinton Town Museum | Hopkinton | St. Lawrence | Thousand Islands | Local history | information |
| Horace Greeley House | Chappaqua | Westchester | Lower Hudson | Historic house | Operated by the New Castle Historical Society, 19th-century home of newspaper editor and later presidential candidate Horace Greeley |
| Horicon Museum | Brant Lake | Warren | Adirondack Region | Local history | website, operated by the Town of Horicon Historical Society |
| Hornell Erie Depot Museum | Hornell | Steuben | Finger Lakes | Railroad | website, Erie Railroad memorabilia |
| Horseheads Historical Society Depot Museum | Horseheads | Chemung | Finger Lakes | Local history | website |
| House of Frankenstein Wax Museum | Lake George | Warren | Adirondack Region | Wax | website, wax models of scary figures |
| Howe Caverns | Howes | Schoharie | Capital District | Natural history | Cavern tours and the Cave House Museum of Mining & Geology |
| Howland Stone Store Museum | Sherwood | Cayuga | Finger Lakes | Local history | |
| Hudson Highlands Nature Museum | Cornwall | Orange | Mid-Hudson | Natural history | website |
| Hudson River Maritime Museum | Kingston | Ulster | Mid-Hudson | Maritime | History of shipping, boating and industry on the Hudson River and its tributaries; operates the Rondout Light for tours |
| Hudson River Museum | Yonkers | Westchester | Lower Hudson | Multiple | Art, natural history, planetarium |
| Hunting Tavern Museum | Andes | Delaware | Central Leatherstocking | Historic site | website, operated by the Andes Society for History and Culture |
| Hurley Heritage Society Museum | Kingston | Ulster | Mid-Hudson | Historic house | website, also known as Col. Jonathan Elmendorf House |
| Hyde Collection | Glens Falls | Warren | Adirondack Region | Art | Private art collection in original home context, includes American, French and Italian art, furnishings, textiles, silver and ceramics |
| Hyde Hall | Springfield | Otsego | Central Leatherstocking | Historic house | Adjacent to Glimmerglass State Park, turn-of-the-19th-century mansion |
| Hyde Park Station | Hyde Park | Dutchess | Mid-Hudson | Railroad | Includes area's railroad history, artifacts and model railroad |
| Interlaken Historical Society Museum | Interlaken | Seneca | Finger Lakes | Local history | website |
| International Boxing Hall of Fame | Canastota | Madison | Central Leatherstocking | Sports | |
| International Mask & Puppet Museum | Syracuse | Onondaga | Finger Lakes | Puppetry | website, part of Open Hand Theater |
| International Motor Racing Research Center | Watkins Glen | Schuyler | Finger Lakes | Sports | Archives, research library & exhibits |
| Ira G. Ross Aerospace Museum | Buffalo | Erie | Buffalo Niagara Region | Aerospace | Formerly the Niagara Aerospace Museum |
| Irish American Heritage Museum | Albany | Albany | Capital District | Ethnic | History and heritage of the Irish in America |
| Iron Center Museum | Port Henry | Essex | Adirondack Region | Industry - Iron | Railroad and mining history, operated by the Moriah Historical Society |
| Iron Island Museum | Buffalo | Erie | Buffalo Niagara Region | Local history | website, operated by the Iron Island Preservation Society of Lovejoy |
| Iroquois Indian Museum | Howes Cave | Schoharie | Capital District | Native American | Iroquois culture and art |
| Jacob Blauvelt House | New City | Rockland | Lower Hudson | Historic house | Operated by the Historical Society of Rockland County, mid-19th-century period farmhouse |
| Jacob Purdy House | White Plains | Westchester | Lower Hudson | Historic house | Maintained by the White Plains Historical Society, George Washington's headquarters during the Battle of White Plains 1776 and in 1778 |
| Jacob T. Walden Stone House | Walden | Orange | Mid-Hudson | Historic house | 18th-century period house operated by the Walden Historical Society |
| Jamesville Community Museum | Jamesville | Onondaga | Central New York | Local history | Located in the former Saint Mark's Church |
| Java Historical Society Museum | Java | Wyoming | Buffalo Niagara Region | Local history | Operated by appointment |
| Jay Heritage Center | Rye | Westchester | Lower Hudson | Historic house | Home of and museum about John Jay |
| Jean Hasbrouck House | New Paltz | Ulster | Mid-Hudson | Historic house | Part of Historic Huguenot Street, early 18th-century Dutch house |
| Jefferson County Historical Society Museum | Watertown | Jefferson | Thousand Islands | Local history | |
| Jell-O Gallery | Le Roy | Genesee | Buffalo Niagara Region | Food and drink | Operated by the Le Roy Historical Society, history and memorabilia of Jell-O |
| John Brown Farm and Gravesite | North Elba | Essex | Adirondack Region | Historic house | Home and final resting place of abolitionist John Brown |
| John D. Murray Firefighters Museum | Oswego | Oswego | Adirondack Region | Firefighting | Facebook site |
| John Jay Homestead State Historic Site | Katonah | Westchester | Lower Hudson | Historic house | |
| John Kane House | Pawling | Dutchess | Mid-Hudson | Historic house | Operated by the Historical Society of Quaker Hill and Pawling, 18th-century house with period furnishings and local history exhibits |
| Johnson Hall State Historic Site | Johnstown | Fulton | Adirondack Region | Historic house | 18th-century home of Sir William Johnson, an Irish pioneer and British Indian agent in the Province of New York |
| Johnstown Historical Society Museum | Johnstown | Fulton | Adirondack Region | Local history | |
| Johnston House | Geneva | Seneca | Finger Lakes | Historic house | website, operated by the Geneva Historical Society, contains the Mike Weaver Drain Tile Museum |
| John William Draper House | Hastings-on-Hudson | Westchester | Lower Hudson | Historic house | Museum of the Hastings Historical Society |
| Joseph Horton House | Wappingers Falls | Dutchess | Mid-Hudson | Historic house | Pre-Revolutionary War Dutch Colonial home, open by appointment |
| Joseph Smith Farm | Palmyra | Wayne | Finger Lakes | Historic house | Home and farm of Latter Day Saint movement founder Joseph Smith, Jr. |
| Karpeles Manuscript Library Museum | Buffalo | Erie | Buffalo Niagara Region | Library | |
| Karpeles Manuscript Library Museum | Newburgh | Orange | Mid-Hudson | Library | Exhibits from its collections |
| Katonah Museum of Art | Katonah | Westchester | Lower Hudson | Art | |
| Kenan Center | Lockport | Niagara | Buffalo Niagara Region | Art | website, visual and performing arts center with gallery |
| Kent-Delord House Museum | Plattsburgh | Clinton | Adirondack Region | Historic house | Features 19th-century period furnishings |
| Kiersted House Museum | Saugerties | Ulster | Mid-Hudson | Historic house | Operated by the Saugerties Historical Society, 18th-century house |
| Kinetic Gallery | Geneseo | Livingston | Finger Lakes | Art | website, part of SUNY Geneseo |
| Kinnear Museum of Local History | Lake Luzerne | Warren | Adirondack Region | Local history | website, operated by the Hadley-Luzerne Historical Society |
| Klyne Esopus Museum | Esopus | Ulster | Mid-Hudson | Local history | |
| Knickerbocker Mansion | Schaghticoke | Rensselaer | Capital District | Historic house | Operated by the Knickerbocker Historical Society, late 18th-century mansion |
| Knight-Sutton Museum | Akron | Erie | Buffalo Niagara Region | Local history | website, operated by the Newstead Historical Society |
| Knox's Headquarters State Historic Site | New Windsor | Orange | Mid-Hudson | Historic house | Revolutionary War headquarters for General Henry Knox |
| Kykuit | Mount Pleasant | Westchester | Lower Hudson | Historic house | Also known as John D. Rockefeller Estate, 40-room mansion with art collection, gardens |
| Lake George Historical Association Museum | Lake George | Warren | Adirondack Region | Local history | website |
| Lake Placid Winter Olympic Museum | Lake Placid | Essex | Adirondack Region | Sports | Memorabilia of the 1932 & 1980 Lake Placid Winter Olympics |
| Lake Placid-North Elba Historical Society Museum | Lake Placid | Essex | Adirondack Region | Local history | website |
| Lake Pleasant Museum | Lake Pleasant | Hamilton | Adirondack Region | Local history | Operated by the Historical Society of Lake Pleasant & Speculator |
| Lancaster District School No. 6 | Lancaster | Erie | Buffalo Niagara Region | Education | Open by appointment with the Lancaster Historical Society |
| Lancaster Historical Society Museum | Lancaster | Erie | Buffalo Niagara Region | Local history | website |
| Lansing Manor House | North Blenheim | Schoharie | Capital District | Historic house | Early 19th-century period house |
| Le Roy House | LeRoy | Genesee | Buffalo Niagara Region | Historic house | Operated by the Le Roy Historical Society |
| Lederer Lockhart Bridge Galleries | Geneseo | Livingston | Finger Lakes | Art | website, three art galleries at State University of New York at Geneseo |
| Lehigh Valley Railroad Historical Society Station Museum | Shortsville | Ontario | Finger Lakes | Railroad | website |
| Leon Historical Society Museum | Leon | Cattaraugus | Buffalo Niagara Region | Local history | |
| Lewiston Museum | Lewiston | Niagara | Buffalo Niagara Region | Local history | website, operated by the Historical Association of Lewiston |
| Liberty Museum & Arts Center | Liberty | Sullivan | Mid-Hudson | Art | website |
| Light Work | Syracuse | Onondaga | Central New York | Art | Non-profit photography center |
| Lincoln Depot Museum | Peekskill | Westchester | Lower Hudson | Biographical | History and ties between Abraham Lincoln and Peekskill |
| Lisbon Depot Museum | Lisbon | St. Lawrence | Thousand Islands | Local history | Town's social, agricultural and railway history |
| Little Falls New York Historical Society & Museum | Little Falls | Herkimer | Adirondack Region | Local history | website |
| Little Red Schoolhouse Museum | Chestnut Ridge | Rockland | Lower Hudson | Education | website, operated by the East Ramapo School District |
| Little Red School House Museum | Sterling | Cayuga | Finger Lakes | Local history | Operated by the Sterling Historical Society |
| Liverpool Village Museum | Liverpool | Onondaga | Finger Lakes | Local history | Changing exhibits of local history, grounds also include the Liverpool Willow Museum about the local willow weaving industry, located in the Lucius Gleason House |
| Livingston Art Center | Mount Morris | Livingston | Finger Lakes | Art | website, art center with New Deal Gallery, featuring Works Progress Administration art from the Great Depression, and the Apartment One Gallery for exhibits of regional art |
| Livingston County Historical Society Museum | Geneseo | Livingston | Finger Lakes | Local history | website |
| Livingston History Barn | Livingston | Columbia | Capital District | Local history | website |
| Locust Grove (Samuel F. B. Morse House) | Poughkeepsie | Dutchess | Mid-Hudson | Historic house | 19th-century period furnished house, exhibit on telegraph inventor Samuel Morse |
| Locust Lawn Estate | Gardiner | Ulster | Mid-Hudson | Historic house | 19th-century farm complex, part of Historic Huguenot Street |
| Longyear Museum of Anthropology | Hamilton | Madison | Central Leatherstocking | Anthropology | Part of Colgate University, archaeological and ethnographic materials from Africa, Oceania, and the pre-Columbian cultures of North, Central, and South America |
| Lorenzo State Historic Site | Cazenovia | Madison | Central Leatherstocking | Historic house | Early 19th-century mansion |
| Louis Miller Museum | Hoosick Falls | Rensselaer | Finger Lakes | Local history | website, operated by Hoosick Township Historical Society |
| Lucille Ball-Desi Arnaz Center | Jamestown | Chautauqua | Buffalo Niagara Region | Biographical | Memorabilia of television stars Lucille Ball and Desi Arnaz |
| Lucille Wright Air Museum | Jamestown | Chautauqua | Buffalo Niagara Region | Aerospace | website, air and space education, planetarium |
| Lyndhurst (Jay Gould Estate) | Tarrytown | Westchester | Lower Hudson | Historic house | 19th-century mansion in 67-acre (270,000 m$^2$) park |
| Lyon Mountain Mining and Railroad Museum | Lyon Mountain | Clinton | Adirondack Region | Local history | Includes history of Lyon Mountain mines and the D & H Railroad |
| Mabee Farm Historic Site | Rotterdam Junction | Schenectady | Capital District | Historic house | 17th-century Dutch farm, oldest house still standing in the Mohawk Valley, operated by the Schenectady County Historical Society |
| Madam Brett Homestead | Beacon | Dutchess | Mid-Hudson | Historic house | Operated by the Daughters of the American Revolution, early 18th-century home |
| Mandeville Gallery | Schenectady | Schenectady | Capital District | Art | Part of Union College, located in the Nott Memorial, changing exhibits of contemporary art, history and science |
| Manitoga | Garrison | Putnam | Lower Hudson | Historic house | 20th-century home of industrial designer Russel Wright, tours by reservation |
| Manlius Historical Museum | Manlius | Onondaga | Finger Lakes | Local history | website, operated by the Manlius Historical Society |
| Maple Grove (Poughkeepsie, New York) | Poughkeepsie | Dutchess | Mid-Hudson | Historic house | Mid-19th-century house under restoration |
| Marble Schoolhouse | Eastchester | Westchester | Lower Hudson | Local history | Open by appointment with the Eastchester Historical Society |
| Marcella Sembrich Opera Museum | Bolton Landing | Warren | Adirondack Region | Music | Home of opera star Marcella Sembrich, includes fine and decorative arts, personal opera mementos, photographs, costumes, hosts concerts |
| Margaret Reaney Memorial Library & Museum | St. Johnsville | Montgomery | Capital District | Local history | website, includes fine art, sculpture, household and military items |
| Marian E. White Anthropology Research Museum | Buffalo | Erie | Buffalo Niagara Region | Science | Research collection of North American archaeological items, part of University at Buffalo |
| Mark Twain Study | Elmira | Chemung | Finger Lakes | Biographical | website, part of Elmira College, octagonal building where author Mark Twain wrote many of his books |
| Martin Van Buren National Historic Site | Kinderhook | Columbia | Capital District | Historic house | Mid-19th-century mansion and estate of President Martin Van Buren |
| Martisco Station Railway Museum | Camillus | Onondaga | Finger Lakes | Railroad | Operated by the Central New York Chapter, National Railway Historical Society |
| Massena Museum | Massena | St. Lawrence | Thousand Islands | Local history | website |
| Matilda Joslyn Gage Home | Fayetteville | Onondaga | Central New York | Biographical | website, restored home with exhibits about the life of suffragist, abolitionist and author Matilda Joslyn Gage |
| Maurice F. Sweeney Museum | Livonia | Livingston | Finger Lakes | Local history | website, operated by the Livonia Area Preservation & Historical Society |
| Maybrook Railroad Museum | Maybrook | Orange | Mid-Hudson | Railroad | |
| Mayville Depot Museum | Mayville | Chautauqua | Buffalo Niagara Region | Local history | Operated by the Chautauqua Town Historical Society in a historic depot |
| M'Clintock House | Waterloo | Seneca | Finger Lakes | History | Mid-19th-century house is part of Women's Rights National Historical Park |
| McClurg Museum | Westfield | Chautauqua | Buffalo Niagara Region | Historic house | Operated by the Chautauqua County Historical Society, 19th-century period mansion |
| Medina Historical Society Museum | Medina | Orleans | Buffalo Niagara Region | Local history | website |
| Medina Railroad Museum | Medina | Orleans | Buffalo Niagara Region | Railroad | |
| Medora Ball Museum | Otto | Cattaraugus | Buffalo Niagara Region | Local history | |
| Memorial Art Gallery | Rochester | Monroe | Finger Lakes | Art | European and Asian art and antiquities, American art, antiquities from Ancient Greece, Rome and the Middle East; part of the University of Rochester |
| Merestead | Mount Kisco | Westchester | Lower Hudson | Historic house | Early 20th-century mansion and estate, tours by advance reservation |
| Mexico Historical Society Museum | Mexico | Oswego | Thousand Islands | Local history | Facebook site |
| Mid-Hudson Children's Museum | Poughkeepsie | Dutchess | Mid-Hudson | Children's | |
| Middlebury Historical Society | Wyoming | Wyoming | Buffalo Niagara Region | Local history | |
| Midway State Park | Maple Springs | Chautauqua | Buffalo Niagara Region | Amusement | Historic amusement park with museum |
| Military History Society of Rochester | Rochester | Monroe | Finger Lakes | Military | website U.S. Military artifacts from the War of 1812 through current times. |
| Mill Museum | Galen | Wayne | Finger Lakes | Agriculture | website, operated by the Galen Historical Society, farming and household items |
| Millard Fillmore House | East Aurora | Erie | Buffalo Niagara Region | Historic house | 19th-century period home of President Millard Fillmore |
| Mills Mansion | Mount Morris | Livingston | Finger Lakes | Historic house | Mid-19th-century period home, operated by the Mount Morris Historical Society |
| Milton J. Rubenstein Museum of Science and Technology | Syracuse | Onondaga | Finger Lakes | Science | Often referred to as the MOST |
| Miner's Cabin | Franklinville | Cattaraugus | Buffalo Niagara Region | Historic house | website, operated by the Ischua Valley Historical Society |
| Minerva Historical Society Museum | Olmstedville | Essex | Adirondack Region | Local history | website |
| Mohawk Valley Center for the Arts | Little Falls | Herkimer | Adirondack Region | Art | website |
| Montgomery Place | Annandale-on-Hudson | Dutchess | Mid-Hudson | Historic house | One of the Historic Hudson Valley houses, early 19th-century estate |
| Moore Historical Museum | Waddington | St. Lawrence | Thousand Islands | Local history | website |
| Morehouse Historical Museum | Morehouse | Hamilton | Adirondack Region | Local history | website |
| Morrisville State College Wildlife Museum | Morrisville | Madison | Central Leatherstocking | Natural history | website, open by appointment |
| Motorcyclepedia | Newburgh | Orange | Mid-Hudson | Transportation | Over 500 motorcycles from 1897 onward |
| Mount Gulian | Fishkill | Dutchess | Mid-Hudson | Historic house | Reconstructed 18th-century Dutch manor house |
| Mount Lebanon Shaker Village | New Lebanon | Columbia | Capital District | Open air | Shaker village under restoration, includes walking tours and exhibits at Shaker Museum | Mount Lebanon |
| Mount Morris Dam | Mount Morris | Livingston | Finger Lakes | Natural history | William B. Hoyt II Visitor Center features a large atrium, museum and theater |
| Munson-Williams-Proctor Arts Institute Museum of Art | Utica | Oneida | Central Leatherstocking | Art | Arts center with museum featuring European and American art |
| Muscoot Farm | Somers | Westchester | Lower Hudson | Agriculture | Historic working dairy farm |
| Museum at Bethel Woods | Bethel | Sullivan | Mid-Hudson | Culture | History and culture of 1969 Woodstock Festival |
| Museum at the Creamery | Skaneateles | Onondaga | Central New York | Local history | website, operated by the Skaneateles Historical Society |
| Museum of Automobile History | Syracuse | Onondaga | Finger Lakes | Automotive | website, history of the automobile from the 18th century, includes cars, photos, art, models, designs, memorabilia |
| Museum of Curiosities | Cazenovia | Madison | Central Leatherstocking | Natural history | website, part of the Cazenovia Public Library, artifacts relating to natural history, geology, ethnography, archaeology, historic relics, art and local history |
| The Museum of disABILITY History | Williamsville | Erie | Buffalo Niagara Region | Medical | History of people with disabilities from medieval times to the present era |
| Museum of the Earth | Ithaca | Tompkins | Finger Lakes | Natural history | Focuses on paleontology |
| Museum of Rhinebeck History | Rhinebeck | Dutchess | Mid-Hudson | Local history | website |
| Museum of the Early American Circus | Somers | Westchester | Lower Hudson | Multiple | Operated by the Somers Historical Society, local and area circus history |
| Museum of Wayne County History | Lyons | Wayne | Finger Lakes | Prison | website, operated by the Wayne County Historical Society, former county jail and sheriff's residence, also local history |
| Museum Village | Monroe | Orange | Mid-Hudson | Open air | website, 19th-century village |
| Napanoch Train Station Museum | Napanoch | Ulster | Mid-Hudson | Railroad | |
| Nash House Museum | Buffalo | Erie | Buffalo Niagara Region | Historic house | 20th-century home of important leader of Buffalo's African-American community |
| Nathaniel Hill Brick House | Montgomery | Orange | Mid-Hudson | Historic house | 18th-century estate of Nathaniel Hill |
| National Abolition Hall of Fame & Museum | Peterboro | Madison | Finger Lakes | History | History and important people of the anti-slavery movement in the United States, located in the Smithfield Presbyterian Church |
| National Baseball Hall of Fame and Museum | Cooperstown | Otsego | Central Leatherstocking | Sports | |
| National Bottle Museum | Ballston Spa | Saratoga | Adirondack Region | Industry - Bottle making | Antique glass bottles and tools |
| National Comedy Center | Jamestown | Chautauqua | Buffalo Niagara Region | Comedy | State of the art museum of comedy in Lucille Ball's hometown. |
| National Distance Running Hall of Fame | Utica | Oneida | Adirondack Region | Sports | |
| National Memorial Day Museum | Waterloo | Seneca | Finger Lakes | History | Memorabilia and history of the birth of Memorial Day |
| National Museum of Dance | Saratoga Springs | Saratoga | Capital District | Dance | |
| National Museum of Racing and Hall of Fame | Saratoga Springs | Saratoga | Capital District | Sports | |
| National Purple Heart Hall of Honor | New Windsor | Orange | Mid-Hudson | Military | |
| National Saint Kateri Tekakwitha Shrine | Fonda | Montgomery | Mohawk Valley | Native American | website, life of Kateri Tekakwitha, a Mohawk-Algonquian woman from New York and an early convert to Christianity and area Native American artifacts |
| National Shrine of the North American Martyrs | Auriesville | Montgomery | Mohawk Valley | Religious | Roman Catholic shrine dedicated to the Jesuit missionaries who were martyred at the Mohawk village of Ossernenon between 1642 and 1646 |
| National Soaring Museum | Elmira | Chemung | Finger Lakes | Aviation | |
| National Toy Hall of Fame | Rochester | Monroe | Finger Lakes | Toy | Part of The Strong |
| National Warplane Museum | Geneseo | Livingston | Finger Lakes | Aviation | Aircraft of the World War II and Korean War eras |
| National Women's Hall of Fame | Seneca Falls | Seneca | Finger Lakes | History | |
| Native American Museum of Art | Tuscarora Reservation | Niagara | Buffalo Niagara Region | Native American | website, Native American art and culture, particularly Iroquois and Tuscarora |
| Nellis Tavern | St. Johnsville | Montgomery | Mohawk Valley | Historic house | Operated by the Palatine Settlement Society, restored 18th-century tavern |
| Ner-A-Car Motorcycle Museum | Syracuse | Onondaga | Central New York | Transportation | Motorcycles built in New York state |
| Neuberger Museum of Art | Purchase | Westchester | Lower Hudson | Art | contemporary art; part of Purchase College |
| Neversink Valley Museum of History and Innovation | Cuddebackville | Orange | Mid-Hudson | Canals | website, history of the Delaware & Hudson Canal |
| Newark-Arcadia Museum | Newark | Wayne | Finger Lakes | Local history | website, operated by the Newark-Arcadia Historical Society, also the 1876 Marbletown Schoolhouse |
| Newark Valley Depot and Museum | Newark Valley | Tioga | Finger Lakes | Railroad | website, operated by the Newark Valley Historical Society |
| New Windsor Cantonment State Historic Site | Vails Gate | Orange | Mid-Hudson | Military | Reconstruction of the final encampment of the Continental Army of the Revolutionary War |
| New Woodstock Regional Historical Society Museum | New Woodstock | Madison | Central Leatherstocking | Local history | website |
| New York Museum of Transportation | Rush | Monroe | Finger Lakes | Transportation | Historic vehicles and photographs, trolley rides, track car rides, model railroad displays |
| New York State Capitol | Albany | Albany | Capital District | History | |
| New York State Civilian Conservation Corps Museum | New Lisbon | Otsego | Capital District | History | Located in Gilbert Lake State Park, area activities of the Civilian Conservation Corps |
| New York State Country Music Hall of Fame | Cortland | Cortland | Finger Lakes | Music | website, located at the Cortland Country Music Park |
| New York State Executive Mansion | Albany | Albany | Capital District | Historic house | |
| New York State Grange Museum | Cortland | Cortland | Finger Lakes | History | website, history and artifacts of the New York State Grange |
| New York State Military Museum | Saratoga Springs | Saratoga | Capital District | Military | website, state's military history |
| New York State Museum | Albany | Albany | Capital District | Multiple | Art, artifacts (prehistoric and historic), and natural history artifacts that reflect New York State's cultural, natural, and geological development |
| New York State Wine Museum of Greyton H. Taylor | Hammondsport | Steuben | Finger Lakes | Multiple | Food and drink |
| Niagara Arts & Cultural Center | Niagara Falls | Niagara | Buffalo Niagara Region | Art | Includes two galleries |
| Niagara Falls Underground Railroad Heritage Center | Niagara Falls | Niagara | Buffalo Niagara Region | History | Museum about the Underground Railroad in Niagara Falls |
| Niagara Gorge Discovery Center | Niagara Falls | Niagara | Buffalo Niagara Region | Natural history | Natural and local history of Niagara Falls and the surrounding area, formerly the Schoellkopf Geological Museum |
| Niagara History Center | Lockport | Niagara | Buffalo Niagara Region | Open air | website, eight building museum complex showcasing early pioneer life, business and industry, includes the Col. William M. and Nancy Ralston Bond House, operated by the Niagara County Historical Society |
| Niagara Power Visitors Center | Lewiston | Niagara | Buffalo Niagara Region | Science | exhibits about water-powered electricity generation |
| Niagara Science Museum | Niagara Falls | Niagara | Buffalo Niagara Region | Science | Includes antique science instruments and philosophical apparatus |
| Niagara's Wax Museum of History | Niagara Falls | Niagara | Buffalo Niagara Region | Wax | website |
| North Creek Depot Museum | North Creek | Warren | Adirondack Region | Railroad | Area railroad history, place where Theodore Roosevelt learned of the assassination of President William McKinley and of his accession to the Presidency of the United States |
| Northeast Classic Car Museum | Norwich | Chenango | Central Leatherstocking | Automotive | Over 150 classic and antique cars |
| North Tonawanda History Museum | North Tonawanda | Niagara | Buffalo Niagara Region | Local history | website |
| Norfolk Historical Museum | Norfolk | St. Lawrence | Thousand Islands | Local history | website |
| Northup Carriage House Museum | Wolcott | Wayne | Finger Lakes | Local history | website, home of the Wolcott Historical Society and Museum |
| Northville & Northampton Historical Society Museum | Northville | Fulton | Adirondack Region | Local history | |
| Nunda Museum and Rose Shave Gallery | Nunda | Livingston | Finger Lakes | Local history | website, operated by the Nunda Historical Society |
| Oak Orchard Lighthouse Museum | Medina | Orleans | Buffalo Niagara Region | Maritime | Reconstructed 1909 lighthouse on Lake Ontario |
| Olana State Historic Site | Greenport | Columbia | Capital District | Historic house | Former estate of artist Frederic Edwin Church |
| Old Austerlitz Village | Austerlitz | Columbia | Capital District | Open air | website, operated by the Austerlitz Historical Society, early 19th-century village buildings |
| Old Fort House Museum | Fort Edward | Washington | Adirondack Region | Historic house | 18th-century house depicting life from the 1770s through the 1940s |
| Old Fort Johnson | Amsterdam | Montgomery | Mohawk Valley | Historic house | 18th-century house with exhibits about the social, cultural, military and industrial past of the Mohawk Valley |
| Old Fort Niagara State Historic Site | Youngstown | Niagara | Buffalo Niagara Region | Military | Part of Fort Niagara State Park, restored fort dating from the 17th century, costumed interpreters |
| Old Middlefield Schoolhouse Museum | Middlefield | Otsego | Central Leatherstocking | Local history | Operated by the Town of Middlefield Historical Association |
| Old Quaker Store Museum | Salamanca | Cattaraugus | Buffalo Niagara Region | Local history | History and development of Allegany State Park |
| Old Rhinebeck Aerodrome | Rhinebeck | Dutchess | Mid-Hudson | Aviation | Living museum of pre-World War II airplanes, automobiles and airplane engines |
| Old Stone Fort Museum Complex | Schoharie | Schoharie | Mohawk Valley | Open air | Includes an early 18th-century home, a 1780s Dutch barn, an 1830s law office, an 1890s one-room schoolhouse, and a 1772 stone church that was attacked during the American Revolution |
| Oliver Rice Homestead | Mayfield | Fulton | Adirondack Region | Historic house | 1790 homestead with exhibits depicting local history including the glove industry |
| Omi International Arts Center | Ghent | Columbia | Capital District | Art | Features the Fields Sculpture Park and exhibitions in the Charles B. Benenson Visitors Center & Gallery |
| Oneida Community Mansion House | Oneida | Madison | Central Leatherstocking | Local history | History of the Oneida Community |
| Oneida County Historical Society | Utica | Oneida | Central Leatherstocking | Local history | website |
| Onondaga Historical Museum | Syracuse | Onondaga | Finger Lakes | Local history | website, exhibits include Syracuse China, The Magic Toy Shop, settlers, Native Americans, transportation, industry |
| Ontario County Historical Museum | Canandaigua | Ontario | Finger Lakes | Local history | website, operated by the Ontario County Historical Society |
| Opalka Gallery | Albany | Albany | Capital District | Art | website, part of Sage College of Albany |
| Opus 40 | Saugerties | Ulster | Mid-Hudson | Art | Environmental sculpture park, also features the Quarryman's Museum, collection of antique tools |
| Orange County Farmer's Museum | Montgomery | Orange | Mid-Hudson | Agriculture | website, including farm tools, implements, equipment |
| Orange County Firefighters Museum | Montgomery | Orange | Mid-Hudson | Firefighting | website |
| Orangetown Historical Museum | Orangetown | Rockland | Lower Hudson | Local history | Located at two sites, the Edward Salyer House and the Peter DePew House; changing exhibits of local history and culture |
| Original American Kazoo Factory and Museum | Eden | Erie | Buffalo Niagara Region | Music | website, kazoo history and trivia |
| Oriskany Museum | Oriskany | Oneida | Capital District | Military | website, focuses on the Battle of Oriskany which took place in 1777, the village of Oriskany NY, and the aircraft carrier USS Oriskany |
| Ortlip Gallery | Houghton | Allegany | Buffalo Niagara Region | Art | website, part of Houghton University |
| Ossining Historical Society Museum | Ossining | Westchester | Lower Hudson | Local history | Open by appointment |
| Oswego Railroad Museum | Oswego | Oswego | Adirondack Region | Railroad | website |
| Our Lady of Victory Basilica | Lackawanna | Erie | Buffalo Niagara Region | Religious | Includes museum about founder Father Nelson Baker and the history of the basilica |
| Palatine House Museum | Schoharie | Schoharie | Capital District | Historic house | website, operated by the Schoharie Colonial Heritage Association, Colonial living museum |
| Palentown School House Museum | Accord | Ulster | Mid-Hudson | Education | One-room schoolhouse, open twice a year and by appointment |
| Palmyra Historic Museum | Palmyra | Wayne | Finger Lakes | Local history | website, operated by Historic Palmyra |
| Painted Post-Erwin Museum at the Depot | Painted Post | Steuben | Finger Lakes | Local history | Operated by the Corning-Painted Post Historical Society in a late 19th-century railroad depot |
| Parishville Museum | Parishville | St. Lawrence | Thousand Islands | Local history | website, features collection of hand-carved circus miniatures |
| Parker-O'Malley Air Museum | Ghent | Columbia | Capital District | Aviation | Open by appointment, located at the Columbia County Airport |
| Patriot Of Lake George | Lake George | Warren | Adirondack Region | Military | website, dedicated to the remembrance of veterans and service personnel of all branches |
| Peck's Lake Historical Society & Museum | Gloversville | Fulton | Adirondack Region | Education | 1857 one-room schoolhouse and nature trail |
| Peekskill Museum | Peekskill | Westchester | Lower Hudson | Historic house | website |
| Pember Museum of Natural History | Granville | Washington | Adirondack Region | Natural history | website, mounted animals, rocks and minerals, fossils, dried plant specimens, adjacent nature preserve |
| Penfield Homestead Museum | Crown Point | Essex | Adirondack Region | Industry - Iron | History of the 19th-century ironworking industry in the North Country |
| Perrella Gallery | Johnstown | Fulton | Adirondack Region | Art | website, part of Fulton–Montgomery Community College |
| Perrysburg Historical Museum | Perrysburg | Cattaraugus | Buffalo Niagara Region | Local history | information, located in Town Hall |
| Peter Whitmer log home | Waterloo | Seneca | Finger Lakes | Historic house | Replica early 19th-century log home, important site in Latter Day Saint history |
| Phelps General Store | Palmyra | Wayne | Finger Lakes | History | website, operated by Historic Palmyra, example of the General Store when it was at its prime in 1890 |
| Phelps Mansion | Binghamton | Broome | Central Leatherstocking | Historic house | Furnished Victorian mansion, art exhibits |
| Philipsburg Manor House | Sleepy Hollow | Westchester | Lower Hudson | Open air | Mid-18th-century period house, working water-powered grist mill and millpond, an 18th-century barn, a slave garden, and a reconstructed tenant farm house |
| Philipse Manor Hall State Historic Site | Yonkers | Westchester | Lower Hudson | Historic house | Museum of history, art and architecture since 1912 |
| Picker Art Gallery | Hamilton | Madison | Central Leatherstocking | Art | Part of Colgate University, located in the Dana Arts Center |
| Pickering-Beach Historical Museum | Sackets Harbor | Jefferson | Thousand Islands | Historic house | Operated by the Sackets Harbor Historical Society in the Joshua Pickering House |
| Pines Museum | Slate Hill | Orange | Mid-Hudson | Historic house | |
| Pioneer Oil Museum | Bolivar | Allegany | Buffalo Niagara Region | Industry - Oil | website, area oil and gas industry |
| Pierrepont Museum | Pierrepont | St. Lawrence | Thousand Islands | Local history | |
| Plattsburgh State Art Museum | Plattsburgh | Clinton | Adirondack Region | Art | A museum without walls comprising several galleries, exhibition areas and a sculpture park at State University of New York at Plattsburgh |
| Potsdam Public Museum | Potsdam | St. Lawrence | Thousand Islands | Local history | website, local history, decorative arts |
| Pound Ridge Museum | Pound Ridge | Westchester | Lower Hudson | Local history | website, operated by the Pound Ridge Historical Society |
| Print Shop Museum | Palmyra | Wayne | Finger Lakes | Industry | website, operated by Historic Palmyra, historic printing equipment |
| Pratt House Museum | Fulton | Oswego | Central New York | Local history | 1861 mansion with local history exhibits |
| Pulaski Historical Society Museum | Pulaski | Oswego | Thousand Islands | Local history | |
| Putnam History Museum | Cold Spring | Putnam | Lower Hudson | Local history | website, history of Putnam County, Philipstown, the West Point Foundry, and the Hudson Highlands |
| Putnam Valley Historical Society Museum | Putnam Valley | Putnam | Lower Hudson | Local history | website |
| Quincy Square Museum | Earlville | Madison | Central Leatherstocking | Local history | website |
| Railroad Museum of the Niagara Frontier | North Tonawanda | Niagara | Buffalo Niagara Region | Railroad | |
| Railway Historical Society of Northern New York | Croghan | Lewis | Adirondack Region | Railroad | website, depot museum with railway exhibits and trains |
| Regina A. Quick Center for the Arts (St. Bonaventure) | St. Bonaventure | Cattaraugus | Buffalo Niagara Region | Art | website, part of St. Bonaventure University |
| Remington Country Store and Museum | Ilion | Herkimer | Adirondack Region | Firearms | Remington Arms firearms from the early 19th century to the present |
| Rensselaer County Historical Society | Troy | Rensselaer | Capital District | Local history | Also operates Hart-Cluett Mansion as a historic house museum |
| Richard F. Brush Art Gallery | Canton | St. Lawrence | Thousand Islands | Art | website, part of St. Lawrence University |
| Richardson-Bates House | Oswego | Oswego | Adirondack Region | Historic house | Operated by the Oswego County Historical Society, late 19th-century period mansion, local history exhibits |
| Richburg-Wirt Historical Society Museum | Richburg | Allegany | Buffalo Niagara Region | Local history | information |
| Rich-Twinn Octagon House | Akron | Erie | Buffalo Niagara Region | Historic house | Mid-19th-century octagonal house, operated by the Newstead Historical Society |
| Ripley House Museum | Adams | Jefferson | Thousand Islands | Local history | Operated by the Historical Association of South Jefferson, 25-room house with local history displays |
| Rippleton Schoolhouse | Cazenovia | Madison | Central Leatherstocking | Education | Restored 1880s period one-room schoolhouse |
| River Lea | Grand Island | Niagara | Buffalo Niagara Region | Historic house | Operated by the Grand Island Historical Society, located in Beaver Island State Park, Victorian summer home of Lewis F. Allen, the uncle of President Grover Cleveland |
| Roberson Museum and Science Center | Binghamton | Broome | Central Leatherstocking | Multiple | Local and natural history, science, art, planetarium |
| Robert Green Ingersoll Birthplace Museum | Dresden | Yates | Finger Lakes | Historic house | 19th-century birthplace of noted agnostic and politician Robert G. Ingersoll |
| Robert H. Jackson Center | Jamestown | Chautauqua | Buffalo Niagara Region | Biographical | Life of Robert H. Jackson, Associate Justice of the Supreme Court of the United States from 1941 to 1954 |
| Robert Jenkins House | Hudson | Columbia | Capital District | Historic house | website, operated by the Hendrick Hudson Chapter of the Daughters of the American Revolution |
| Robert Louis Stevenson Memorial Cottage and Museum | Saranac Lake | Essex | Adirondack Region | Historic house | |
| Robert M. Linsley Geology Museum | Hamilton | Madison | Central Leatherstocking | Natural history | website, part of Colgate University, minerals, rocks, fossils, state geology |
| Rochester & Genesee Valley Railroad Museum | West Henrietta | Monroe | Finger Lakes | Railroad | Accessed via a track car from the New York Museum of Transportation, houses over 40 pieces of railroad rolling stock |
| Rochester Contemporary Art Center | Rochester | Monroe | Finger Lakes | Art | Contemporary art |
| Rochester Medical Museum and Archives | Rochester | Monroe | Finger Lakes | Medical | website, corporate memory of the Rochester General Health System and includes the Baker-Cederberg Museum and Archives with exhibits on the history of medicine in Rochester, New York, the Genesee Hospital Archives and the archival records of other area hospitals |
| Rochester Museum and Science Center | Rochester | Monroe | Finger Lakes | Science | |
| Rockland Center for the Arts | West Nyack | Rockland | Lower Hudson | Art | Cultural center with exhibition gallery |
| Rockwell Museum | Corning | Steuben | Finger Lakes | Art | American and Native American art and artifacts |
| Roe Cobblestone Schoolhouse | Butler | Wayne | Finger Lakes | Education | Operated by the Butler Historical Society |
| Roeliff Jansen Historical Society Museum | Copake Falls | Columbia | Capital District | Local history | Located in a historic church building |
| Rogers Island Visitors Center | Fort Edward | Washington | Adirondack Region | History | website, history of Rogers Island, area prehistory, culture and military history up to the American Revolution |
| Roger Tory Peterson Institute of Natural History | Jamestown | Chautauqua | Buffalo Niagara Region | Natural history | website |
| Rome Historical Society Museum | Rome | Oneida | Central Leatherstocking | Local history | website |
| Rome Sports Hall of Fame and Museum | Rome | Oneida | Central Leatherstocking | Sports | website |
| Romulus Historical Society Museum | Romulus | Seneca | Finger Lakes | Local history | website |
| Roscoe Ontario & Western Railway Museum | Roscoe | Sullivan | Mid-Hudson | Railroad | website, information |
| Rose Hill Mansion | Fayette | Seneca | Finger Lakes | Historic house | Operated by the Geneva Historical Society, mid-19th-century mansion |
| Rough and Ready Firehouse Museum | Greenwich | Washington | Adirondack Region | Firefighting | Open once a year for tours |
| Roxbury Railroad Station Museum | Roxbury | Delaware | Central Leatherstocking | Railroad | |
| Rural Life Museum | King Ferry | Cayuga | Finger Lakes | Local history | website, operated by Genoa Historical Association, one-room schoolhouse, household, agriculture and rural life artifacts |
| Rushford Museum | Rushford | Allegany | Buffalo Niagara Region | Local history | information, operated by the Rushford Historical Society |
| Ruth and Elmer Wellin Museum of Art | Clinton | Oneida | Central Leatherstocking | Art | Part of Hamilton College, changing exhibits of art and photography |
| Ruth Howe-Prescott House | Franklinville | Cattaraugus | Buffalo Niagara Region | Historic house | website, information, open by appointment with the Ischua Valley Historical Society |
| Sackets Harbor Art Center | Sackets Harbor | Jefferson | Thousand Islands | Art | website, home of the Arts Association of Northern New York |
| Sackets Harbor Battlefield State Historic Site | Sackets Harbor | Jefferson | Thousand Islands | Military | War of 1812 military reenactments in the summer |
| Safe Haven Museum and Education Center | Oswego | Oswego | Adirondack Region | History | Stories of the 982 refugees from World War II who were allowed into the United States as "guests" of President Franklin D. Roosevelt, housed at Fort Ontario |
| Saint Marianne Cope Shrine and Museum | Syracuse | Onondaga | Central New York | Religious | website, shrine and museum with relics and exhibits about the life of Marianne Cope |
| Saint Paul's Church National Historic Site | Mount Vernon | Westchester | Lower Hudson | Religious | Includes museum of the American Revolution |
| Salamanca Historical Museum | Salamanca | Cattaraugus | Buffalo Niagara Region | Local history | Facebook site, information, operated by the Salamanca Historical Society |
| Salamanca Rail Museum | Salamanca | Cattaraugus | Buffalo Niagara Region | Railroad | information |
| Salmon River International Sport Fishing Museum | Altmar | Oswego | Adirondack Region | Sports | website, antique fishing rods, rare lures, reels and tackle |
| Salt Museum | Liverpool | Onondaga | Central New York | Industry - Salt | Located in Onondaga Lake Park, history of salt production in Syracuse |
| Salvation Army Heritage Museum | West Nyack | Rockland | Lower Hudson | Religious | Facebook site, mission and history of the Salvation Army |
| Sampson State Park Military Museum | Romulus | Seneca | Finger Lakes | Military | |
| Samuel Dorsky Museum of Art | New Paltz | Ulster | Mid-Hudson | Art | website, part of SUNY New Paltz, collections include American art with an emphasis on the Hudson Valley and Catskill Regions, 19th-, 20th- and 21st-century photography and metals |
| Sanborn Area Historical Society Farm Museum and Schoolhouse Museum | Sanborn | Niagara | Buffalo Niagara Region | Agriculture | website Archived 2017-09-13 at the Wayback Machine |
| Sands Ring Homestead Museum | Cornwall | Orange | Mid-Hudson | Historic house | Colonial era house |
| Santanoni Preserve | Newcomb | Essex | Adirondack Region | Historic house | Tours of the buildings of the former camp |
| Saranac Laboratory Museum | Saranac Lake | Franklin | Adirondack Region | Science | website, operated by Historic Saranac Lake, 1894 laboratory of Edward Livingston Trudeau |
| Saratoga Automobile Museum | Saratoga Springs | Saratoga | Capital District | Automotive | |
| Saratoga Harness Hall of Fame & Museum | Saratoga Springs | Saratoga | Capital District | Sports | Facebook site, harness museum with sulkies, racing silks, blacksmith works, horseshoes and metal sculptures |
| Saratoga National Historical Park | Saratoga Springs | Saratoga | Capital District | History | Preserves the site of the Battles of Saratoga, includes Schuyler House |
| Saratoga Springs History Museum | Saratoga Springs | Saratoga | Capital District | Local history | Located in the former Canfield Casino |
| Sardinia Historical Society Museum | Sardinia | Erie | Buffalo Niagara Region | Local history | |
| Saugerties Light | Saugerties | Ulster | Mid-Hudson | Lighthouse | |
| Schenectady County Historical Society Museum | Schenectady | Schenectady | Capital District | Local history | |
| Schenectady Museum | Schenectady | Schenectady | Capital District | Science | |
| Sci-Tech Center of Northern New York | Watertown | Jefferson | Thousand Islands | Science | website |
| Schoharie Crossing State Historic Site | Glen | Montgomery | Mohawk Valley | Canals | Visitor center and remains of an Erie Canal aqueduct |
| Schoharie Valley Railroad Museum | Schoharie | Schoharie | Mohawk Valley | Railroad | website, operated by the Schoharie Colonial Heritage Association |
| Schoolhouse No. 8 History Center & Museum | North Collins | Erie | Buffalo Niagara Region | Education | website, one-room rural schoolhouse |
| School of Pharmacy and Pharmaceutical Sciences Museum of the University at Buffalo | Buffalo | Erie | Buffalo Niagara Region | Medical | website, open by appointment, part of the School of Pharmacy at SUNY Buffalo, includes turn-of-the-20th-century apothecary, raw drugs, patent medicines, pharmacy artifacts |
| Schroeppel Historical Society Museum | Phoenix | Oswego | Thousand Islands | Local history | information |
| Schroon-North Hudson Historical Museum | Schroon Lake | Essex | Adirondack Region | Local history | website, operated by the Schroon-North Hudson Historical Society |
| Schuyler Mansion | Albany | Albany | Capital District | Historic house | 18th-century period house, life of Philip Schuyler |
| Science Discovery Center of Oneonta | Oneonta | Otsego | Central Leatherstocking | Science | Part of State University of New York at Oneonta |
| Sciencenter | Ithaca | Tompkins | Finger Lakes | Science | Hands-on science exhibits |
| Seaway Trail Discovery Center | Sackets Harbor | Jefferson | Thousand Islands | Local history | Culture and heritage of the Great Lakes Seaway Trail and surrounding regions |
| Seneca Falls Historical Society Museum | Seneca Falls | Seneca | Finger Lakes | Historic house | website, late 19th-century Victorian period house |
| Seneca-Iroquois National Museum | Salamanca | Cattaraugus | Buffalo Niagara Region | Native American | website |
| Seneca Museum of Waterways and Industry | Seneca Falls | Seneca | Finger Lakes | Local history | website, area canals, industry |
| Senate House State Historic Site | Kingston | Ulster | Mid-Hudson | Local history | Site of the state's new government during the American Revolution, local history and art displays |
| Shacksboro Schoolhouse Museum | Baldwinsville | Onondaga | Finger Lakes | Local history | website, administered by McHarrie's Legacy |
| Shaker Museum | Mount Lebanon | New Lebanon | Columbia | Capital District | Religious | Located at Mount Lebanon Shaker Village, seasonal exhibitions of Shaker artifacts, and guided walking tours of the historic site |
| Shako:wi Cultural Center | Oneida | Madison | Central Leatherstocking | Native American | website, history and culture of the Oneida Nation |
| Sharon Museum Complex | Sharon | Schoharie | Mohawk Valley | Local history | Includes museum of local history, storage barn, one-room schoolhouse and three-room outhouse |
| Sherwood House | Yonkers | Westchester | Lower Hudson | Historic house | Maintained by the Yonkers Historical Society, 1740 farmhouse |
| Shushan Covered Bridge Museum | Shushan | Washington | Adirondack Region | Local history | Mid-19th-century covered bridge with period machinery and farm implements, adjacent one-room schoolhouse |
| Silas Wright House | Canton | St. Lawrence | Thousand Islands | Historic house | website, home to the St. Lawrence County Historical Association, mid-19th-century period house and local history exhibits |
| Singer Castle | Dark Island | St. Lawrence | Thousand Islands | Historic house | Late 19th-century castle house |
| Six Nations Indian Museum | Onchiota | Franklin | Adirondack Region | Native American | website |
| Skä•noñh - Great Law of Peace Center | Liverpool | Onondaga | Finger Lakes | Native American | website |
| Skene Manor | Whitehall | Washington | Adirondack Region | Historic house | 19th century house |
| Skenesborough Museum | Whitehall | Washington | Adirondack Region | Local history | website |
| Slabsides | West Park | Ulster | Mid-Hudson | Historic house | Log cabin built by naturalist John Burroughs |
| Slate Valley Museum | Granville | Washington | Adirondack Region | Industry - Slate | website, shows how slate is formed and quarried |
| Smith Tavern | Armonk | Westchester | Lower Hudson | Local history | Operated by the North Castle Historical Society |
| Snyder Estate | Rosendale | Ulster | Mid-Hudson | Historic house | Operated by the Century House Historical Society, includes the Century House, Widow Jane Mine and Cement Industry Museum |
| Sodus Bay Lighthouse Museum | Sodus Point | Wayne | Finger Lakes | Lighthouse | Lighthouse, keeper's quarters and lighthouse artifacts |
| Sonnenberg Gardens & Mansion State Historic Park | Canandaigua | Ontario | Finger Lakes | Historic house | Nine formal gardens, 1887 Queen Anne-style mansion and greenhouse complex |
| Southeast Museum | Brewster | Putnam | Lower Hudson | Local history | website, located in the Old Southeast Town Hall |
| Spafford Area Historical Society | Spafford | Onondaga | Central New York | Local history | Operates the Spafford District #3 Side Hill School and the Grange Building by appointment |
| Sports Museum of Dutchess County | Wappingers Falls | Dutchess | Mid-Hudson | Sports | Located at Carnwath Farms Historic Site & Park |
| Springwater Webster Crossing Historical Society | Springwater | Livingston | Finger Lakes | Local history | website, museum open on a limited basis |
| Springville Center for the Arts | Springville | Erie | Buffalo Niagara Region | Art | Community multi-disciplinary arts center with gallery |
| Square House Museum | Rye | Westchester | Lower Hudson | Local history | website, operated by the Rye Historical Society, includes 18th-century period tavern rooms |
| St. Lawrence Power and Equipment Museum | Madrid | St. Lawrence | Thousand Islands | Agriculture | website, antique engines, tractors and related farm equipment |
| Staatsburgh State Historic Site | Staatsburg | Dutchess | Mid-Hudson | Historic house | Mansion designed by McKim, Mead, and White |
| Stafford Museum of History | Stafford | Genesee | Buffalo Niagara Region | Local history | website, operated by the Stafford Historical Society |
| Starr Clark Tin Shop & Underground Rail Road | Mexico | Oswego | Thousand Islands | History | Working tin shop that was the hub of the Abolitionist movement in Oswego County |
| Steepletop | Austerlitz | Columbia | Capital District | Historic house | Home of author Edna St. Vincent Millay |
| Stepping Stones | Katonah | Westchester | Lower Hudson | Historic house | Home of Alcoholics Anonymous co-founder Bill W. and his wife Lois Burnham Wilson, founder of Al-Anon/Alateen, open by appointment |
| Stickley Museum | Fayetteville | Onondaga | Finger Lakes | Decorative arts | website, Stickley furniture |
| Storm King Art Center | Mountainville | Orange | Mid-Hudson | Sculpture park | Outdoor sculpture park on 500 acres (2.0 km$^2$) |
| Stone Arabia Schoolhouse Museum | Cicero | Onondaga | Central New York | Education | Operated by the Cicero Historical Society, one-room schoolhouse and nearby log cabin |
| Stone Mills Museum | Orleans | Jefferson | Thousand Islands | Agriculture | Maintained by the Northern New York Agricultural Historical Society, includes a sawmill, granary, school house, church, display buildings and farm machinery |
| Stone Quarry Hill Art Park | Cazenovia | Madison | Central Leatherstocking | Sculpture park | Outdoor art park on 108 acres (0.44 km$^2$) |
| Stone-Tolan House Museum | Brighton | Monroe | Finger Lakes | Historic house | Operated by the Landmark Society, turn-of-the-19th-century house and tavern |
| Stony Point Battlefield State Historic Site | Stony Point | Rockland | Lower Hudson | Military | Revolutionary War site of the Battle of Stony Point |
| Stony Point Light | Stony Point | Rockland | Lower Hudson | Maritime | Located in Stony Point Battlefield State Historic Site, restored 19th-century lighthouse |
| The Strong | Rochester | Monroe | Finger Lakes | Children's | History of play and toys in American culture, includes The National Museum of Play, the National Toy Hall of Fame and the International Center for the History of Electronic Games |
| Strand Center for the Arts | Plattsburgh | Clinton | Adirondack Region | Art | Performing and visual arts center with a gallery |
| Suffern Railroad Museum | Suffern | Rockland | Lower Hudson | Railroad | |
| Suffern Village Museum | Suffern | Rockland | Lower Hudson | Local history | |
| Suggett House Museum | Cortland | Cortland | Finger Lakes | Local history | website, home of the Cortland County Historical Society |
| Sullivan County Museum | Hurleyville | Sullivan | Mid-Hudson | Local history | website, home of the Sullivan County Historical Society |
| Sunnyside | Tarrytown | Westchester | Lower Hudson | Historic house | Home of noted early American author Washington Irving |
| Sunshine Radio Museum | Sodus | Wayne | Finger Lakes | Technology | website, early years of the electronics industry starting from the turn of the 20th century up to the 1970s |
| Susan B. Anthony House | Rochester | Monroe | Finger Lakes | Historic house | Life and work of women's rights leader Susan B. Anthony |
| Susan C. Lyman Historical Museum | Norwood | St. Lawrence | Thousand Islands | Local history | website |
| Swart-Wilcox House | Oneonta | Otsego | Central Leatherstocking | Historic house | Operated by the Greater Oneonta Historical Society |
| Syracuse University Art Museum | Syracuse | Onondaga | Central New York | Art | website, several galleries at Syracuse University |
| Tabor-Wing House | Dover Plains | Dutchess | Mid-Hudson | Historic house | Restored early 19th-century house |
| Taconic State Park – Copake Falls area | Copake | Columbia | Capital District | Industry - Iron | Features the Iron Works Museum about the 19th-century iron works |
| Tang Teaching Museum | Saratoga Springs | Saratoga | Adirondack Region | Art | Part of Skidmore College, contemporary art |
| Tanglewood Nature Center & Museum | Elmira | Chemung | Finger Lakes | Natural history | website, live animals and natural history exhibits |
| TAUNY | Canton | St. Lawrence | Thousand Islands | Art | website, officially Traditional Arts in Upstate New York, exhibits of area folk culture and crafts |
| Tefft-Steadman House | Marcellus | Onondaga | Finger Lakes | Local history | Operated by the Marcellus Historical Society |
| Ten Broeck Mansion | Albany | Albany | Capital District | Historic house | Headquarters of the Albany County Historical Association, mid-19th-century period house |
| Ten Mile River Scout Museum | Narrowsburg | Sullivan | Mid-Hudson | Scouting | website, history and Scouting memorabilia of Ten Mile River Boy Scout Camp |
| Tennie Burton Museum | Lima | Livingston | Finger Lakes | Historic house | website, operated by the Lima Historical Society |
| Terra Cotta Museum | Alfred | Allegany | Buffalo Niagara Region | Art | Operated by the Alfred Historical Society |
| Terwilliger Museum | Waterloo | Seneca | Finger Lakes | Local history | Part of the Waterloo Library & Historical Society |
| Theodore Roosevelt Inaugural National Historic Site | Buffalo | Erie | Buffalo Niagara Region | Historic house | Turn-of-the-20th-century period rooms, site of the inauguration of President Theodore Roosevelt |
| Thomas Cole House | Catskill | Greene | Capital District | Historic house | |
| Thomas Paine Cottage | New Rochelle | Westchester | Lower Hudson | Historic house | Cottage of American Revolutionary War hero Thomas Paine, decorated in late 18th- to early 19th-century furnishings |
| Thomas Paine Memorial Museum | New Rochelle | Westchester | Lower Hudson | Biographical | Life of American Revolutionary War hero and author Thomas Paine |
| Thousand Islands Arts Center | Clayton | Jefferson | Thousand Islands | Textile | website, formerly The Handweaving Museum and Arts Center, features exhibits of textiles from its permanent textile collection and library, also crafts exhibits |
| Thousand Islands Museum | Clayton | Jefferson | Thousand Islands | Local history | website, includes decoy displays and the Muskie Hall of Fame |
| Town of Chester Museum of Local History | Chestertown | Warren | Adirondack Region | Local history | website |
| Throop Pharmacy Museum | Albany | Albany | Capital District | Medical | website, historic drug store reconstructed at Albany College of Pharmacy |
| Ticonderoga Heritage Museum | Ticonderoga | Essex | Adirondack Region | Local history | website, features over 38 scale models of various local industries |
| Ticonderoga Historical Society | Ticonderoga | Essex | Adirondack Region | Local history | website, non-profit organization organized in 1897 and chartered by the New York State Board of Regents in 1909; primary focus on the Adirondack Mountains and the Lakes Champlain and George regions |
| Time and the Valleys Museum | Grahamsville | Sullivan | Mid-Hudson | History | website 3 floors of fun interactive exhibits, small historic village/1930s themed Lost Catskill Farm. Connecting water, people, and the Catskills |
| Tinker Homestead and Farm Museum | Henrietta | Monroe | Finger Lakes | Historic house | Depicts farming life in the late 19th century |
| Tioga County Historical Society Museum | Owego | Tioga | Finger Lakes | Local history | website |
| Top Cottage | Hyde Park | Dutchess | Mid-Hudson | Historic house | Private retreat designed by and for Franklin D. Roosevelt |
| Town Line Museum | Johnstown | Fulton | Adirondack Region | History | Facebook site, 1950s diner display, memorabilia of the 1950s and 1960s |
| Town of Alabama Museum | Alabama | Genesee | Buffalo Niagara Region | Local history | website, information |
| Town of Hume Museum | Hume | Allegany | Buffalo Niagara Region | Local history | website |
| Town of Hyde Park Historical Society Museum | Hyde Park | Dutchess | Mid-Hudson | Local history | Located in a former firehouse |
| Town of Niagara District School No. 2 | Niagara | Niagara | Buffalo Niagara Region | Education | One-room schoolhouse, operated by the Town of Niagara Historical Society |
| Town of Porter Historical Society Museum | Youngstown | Niagara | Buffalo Niagara Region | Local history | |
| Town of Shandaken Historical Museum | Pine Hill | Ulster | Mid-Hudson | Local history | |
| Trailside Museums and Zoo | Bear Mountain State Park | Rockland | Lower Hudson | Natural history | Located in Bear Mountain State Park, rehabilitated wildlife, area's natural history, history and Native American culture |
| Trailside Nature Museum | Cross River | Westchester | Lower Hudson | Natural history | website, located in Ward Pound Ridge Reservation |
| Trolley Museum of New York | Kingston | Ulster | Mid-Hudson | Transportation | Electric trolley cars |
| Ulysses Historical Society Museum | Trumansburg | Tompkins | Finger Lakes | Local history | website |
| University Art Museum at University at Albany | Albany | Albany | Capital District | Art | Contemporary art part of SUNY Albany |
| UB Art Galleries | Buffalo | Erie | Buffalo Niagara Region | Art | website, includes the UB Anderson Gallery and the UB Art Gallery at the Center for the Arts, part of University at Buffalo |
| Up Yonda Farm | Bolton Landing | Warren | Adirondack Region | Natural history | website, nature center with museum and trails |
| USS Slater | Albany | Albany | Capital District | Maritime | Cannon-class destroyer escort |
| Utica Children's Museum | Utica | Oneida | Adirondack Region | Children's | |
| Valentown Museum | Victor | Ontario | Finger Lakes | Local history | Operated by the Victor Historical Society |
| Van Cortlandt Manor | Croton-on-Hudson | Westchester | Lower Hudson | Historic house | 18th-century manor house |
| Van Horn Mansion | Newfane | Niagara | Buffalo Niagara Region | Historic house | Turn-of-the-20th-century period mansion |
| Van Wyck Homestead Museum | Fishkill | Dutchess | Mid-Hudson | Historic house | Early 18th-century Dutch colonial house |
| Vanderbilt Mansion National Historic Site | Hyde Park | Dutchess | Mid-Hudson | Historic house | Late 19th-century mansion and estate |
| Vestal Museum | Vestal | Broome | Central Leatherstocking | Local history | website, local in the 1881 Vestal Train Station |
| Vintage Tracks Museum | Bloomfield | Ontario | Finger Lakes | Transportation | website, crawler tractors & memorabilia from the early 20th century |
| Walker House Museum | Madrid | St. Lawrence | Thousand Islands | Local history | website, operated by the Madrid Historical Society |
| Walter Elwood Museum | Amsterdam | Montgomery | Mohawk Valley | Multiple | Local history, Victorian, natural history, and items that relate to Mohawk Valley's industrial past |
| Walworth Historical Society Museum | Walworth | Wayne | Finger Lakes | Local history | website |
| Ward W. O'Hara Agricultural Museum | Auburn | Cayuga | Finger Lakes | Agriculture | website, handheld tools, farm equipment, carpenter and blacksmith shops, rural kitchen, bedroom, one-room school, country mercantile and dairy room |
| Warner Museum | Springville | Erie | Buffalo Niagara Region | Local history | website, operated by the Concord NY Historical Society, life and memorabilia of Pop Warner, dolls, tools, 1930s kitchen, items of local interest |
| War of 1812 Museum | Plattsburgh | Clinton | Adirondack Region | Military | History of the War of 1812 and the Battle of Plattsburgh |
| Warrensburgh Museum of Local History | Warrensburg | Warren | Adirondack Region | Local history | website, operated by the Warrensburgh Historical Society |
| Warwick Historical Society | Warwick | Orange | Mid-Hudson | Open air | website, complex of 7 historic buildings |
| Washington's Headquarters State Historic Site | Newburgh | Orange | Mid-Hudson | Historic house | 18th-century home, site of longest-serving headquarters of George Washington during the American Revolutionary War |
| Washington County Fair Farm Museum | Greenwich | Washington | Adirondack Region | Agriculture | website, open seasonally, area crops, farm equipment, displays of tools and crafts, rural life artifacts |
| Waterford Historical Museum and Cultural Center | Waterford | Saratoga | Adirondack Region | Local history | website, located in the Hugh White Homestead |
| Waterman Conservation Education Center | Apalachin | Tioga | Finger Lakes | Natural history | website, environmental education center with museum about local wildlife |
| Watervliet Arsenal Museum | Watervliet | Albany | Capital District | Military | Displays on cannons and guns at the historic Iron Building |
| Watervliet Shaker Historic District | Colonie | Albany | Capital District | Religious | America's first Shaker settlement, museum and tours of the Watervliet Shaker Historic District |
| Wayland Historical Museum | Wayland | Steuben | Finger Lakes | Local history | website |
| Weaver Museum | Potsdam | St. Lawrence | Thousand Islands | Anthropology | website, part of SUNY Potsdam |
| Webster Museum and Historical Society | Webster (town), New York | Monroe | Finger Lakes | Local history | website, Local history, school tours |
| West Monroe Historical Society Museum | West Monroe | Oswego | Adirondack Region | Local history | Facebook site |
| West Point Museum | Highland Falls | Orange | Mid-Hudson | Military | website, history and tours of the United States Military Academy |
| Westchester County Veterans Museum | Somers | Westchester | Lower Hudson | Military | Located in Lasdon Park and Arboretum |
| Western New York Book Arts Center | Buffalo | Erie | Buffalo Niagara Region | Art | website, exhibits of the printed word and image |
| White Pine Camp | Paul Smiths | Franklin | Adirondack Region | Historic camp | Adirondack Great Camp open for tours |
| Wilcox Octagon House | Camillus | Onondaga | Finger Lakes | Historic house | |
| Wild Center | Tupper Lake | Franklin | Adirondack Region | Natural history | |
| Wilder Homestead | Malone | Franklin | Adirondack Region | Historic house | Boyhood home of Almanzo Wilder |
| Wilderstein | Rhinebeck | Dutchess | Mid-Hudson | Historic house | 19th-century Queen Anne–style country house |
| Wildlife Sports and Educational Museum | Vail Mills | Fulton | Adirondack Region | Natural history | website, animal mounts, art, artifacts and memorabilia of hunting, fishing and all sports afield |
| William H. Seward House | Auburn | Cayuga | Finger Lakes | Historic house | 19th-century period home of William H. Seward, exhibits about his life and family |
| William Pryor Letchworth Museum | Castile | Wyoming | Buffalo Niagara Region | Native American | Located in Letchworth State Park |
| Williamson-Pultneyville Historical Society | Pultneyville | Wayne | Finger Lakes | Local history | website, exhibits of local history |
| Wilson Historical Museum | Wilson | Niagara | Buffalo Niagara Region | Local history | website |
| Wilton Heritage Society Museum | Wilton | Saratoga | Adirondack Region | Local history | website |
| Wings of Eagles Discovery Center | Horseheads | Chemung | Finger Lakes | Aviation | website, collection of airplanes and helicopters |
| Woodstock Artists Association & Museum | Woodstock | Ulster | Mid-Hudson | Art | website, work in all media by area artists |
| Women's Rights National Historical Park | Seneca Falls | Seneca | Finger Lakes | History | |
| World Awareness Children's Museum | Glens Falls | Warren | Adirondack Region | Children's | website, cultural awareness museum for children |
| Yager Museum of Art & Culture | Oneonta | Otsego | Central Leatherstocking | Multiple | Part of Hartwick College, art, archaeology, Native American artifacts |
| Yates County History Center | Penn Yan | Yates | Finger Lakes | Local history | Operated by the Yates County Genealogical and Historical Society, includes the L. Caroline Underwood Museum, Oliver House Museum & Scherer Carriage House |
| Yorker Museum | Sinclairville | Chautauqua | Buffalo Niagara Region | Local history | Facebook site, reconstructed mini village with six restored buildings, depicting Sherman life in the mid-19th century |
| Yorktown Museum | Yorktown Heights | Westchester | Lower Hudson | History | website, features 18th-century Colonial rooms, farming, dolls and miniatures, railroad and Native American exhibits |
| Zadock Pratt Museum | Prattsville | Greene | Capital District | Historic house | 19th-century period house |
| Zimmerman House | Horseheads | Chemung | Finger Lakes | Historic house | Open by appointment with the Horseheads Historical Society, late 19th-century home of political cartoonist Eugene Zimmerman |

## Defunct museums

* Balmanno Cottage, Geneva, formerly operated by the Geneva Historical Society, closed in 2013
* Boswell Museum, Springfield Center, no longer any physical museum, just a website, preserves music of the 1920s and 1930s
* Bridgewater Auto Museum, Bridgewater, closed in 1989 after the death of Walt Meyer, its founder
* Campbell-Whittlesey House Museum, Rochester, closed in 2010
* Cudner-Hyatt House, Scarsdale, formerly operated by the Scarsdale Historical Society
* Deansboro Music Museum, Deansboro
* Dinosaur Walk Museum, Riverhead, closed in 2008, branches still exist in Branson, Missouri
* Goudreau Museum of Mathematics in Art and Science, New Hyde Park, closed in 2006
* Greenwood Museum
* Harwood's Grist Mill Farm, East Hartford
* Ithaca College Museum of Art
* Museum of Cartoon Art, Port Chester, became the National Cartoon Museum when the collection moved to Boca Raton, Florida in 1992
* Museum of Long Island Natural Sciences, formerly operated by Stony Brook University
* Museum of the Peaceful Arts
* National Soccer Hall of Fame and Museum, Oneonta, museum closed in 2010, inductions will continue
* New Netherland Museum, Albany, New York, maritime collections including the "Half Moon", a reproduction of the ship that Henry Hudson sailed from Holland to the New World in 1609
* Noteworthy Indian Museum, Amsterdam
* Pedaling History Bicycle Museum, Orchard Park, closed in 2009
* Professional Wrestling Hall of Fame and Museum, Amesterdam Move to Wichita Falls, TX in 2016
* Rail City Historical Museum, Sandy Creek, closed in 2015
* Retro Arcade Museum, Beacon, website
* Ticonderoga Cartoon Museum, Ticonderoga, closed in 2010
* Tired Iron Tractor Museum, Cuylerville, collection of vintage farm machinery, tractors, trucks, horse-drawn equipment, farm toys, sold in 2013, photos
* Toy Town Museum, East Aurora, closed in 2009

## Regions

The "Region" column in the sortable table can be used to help locate museums and understand which museums are in the same area. The list uses regions made up of the following counties or boroughs:
* Adirondack Region (counties all or partly in the Adirondack Park, except counties in the Capital District): Clinton, Essex, Franklin, Fulton, Hamilton, Herkimer, Lewis, Oneida, Saratoga, St. Lawrence, Warren, and Washington counties.
* Buffalo Niagara Region: Allegany, Cattaraugus, Chautauqua, Erie, Genesee, Niagara, Orleans, and Wyoming counties.
* Capital District: Albany, Schenectady, Rensselaer, Columbia, Greene and Saratoga counties.
* Central Leatherstocking: Broome, Delaware, Chenango, Madison, Montgomery, Otsego, Oswego, Schoharie counties.
* Finger Lakes: Onondaga County, Cortland County, Tioga County, Chemung County, Tompkins County, Cayuga County, Seneca County, Wayne County, Monroe County, Livingston County, Ontario County, Yates County, Schuyler County, and Steuben County.
* Lower Hudson: Putnam, Rockland, and Westchester counties.
* Long Island: Nassau and Suffolk counties.
* Mid-Hudson: Dutchess, Orange, Sullivan, and Ulster counties.
* New York City: Boroughs of Brooklyn, Bronx, Manhattan, Queens and Staten Island