# 2022 Challenger de Buenos Aires – Singles

Sebastián Báez was the defending champion but chose not to defend his title.
Juan Manuel Cerúndolo won the title after defeating Camilo Ugo Carabelli 6–4, 2–6, 7–5 in the final.

## Seeds

* Federico Coria (first round)
* Daniel Altmaier (second round)
* Juan Pablo Varillas (withdrew)
* Camilo Ugo Carabelli (final)
* Facundo Bagnis (quarterfinals)
* Felipe Meligeni Alves (first round)
* Santiago Rodríguez Taverna (first round)
* Yannick Hanfmann (second round, withdrew)

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final | Final | Final |
| SE | Mariano Navone | 3 | 5 | | | | | |
| | Juan Manuel Cerúndolo | 6 | 7 | | | | | |
| | Juan Manuel Cerúndolo | 6 | 7 | | Juan Manuel Cerúndolo | 6 | 2 | 7 |
| | | | | 4 | Camilo Ugo Carabelli | 4 | 6 | 5 |
| 4 | Camilo Ugo Carabelli | 6 | 6 | 4 | Camilo Ugo Carabelli | 4 | 6 | 5 |
| | Dmitry Popko | 2 | 1 | | | | | |

### Top half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 1 | F Coria | 2 | 6$^4$ | | | | | | | | | | | | | | |
| | L Darderi | 6 | 7$^7$ | | | L Darderi | 5 | 3 | | | | | | | | | |
| PR | S Nagal | 7 | 6$^4$ | 5 | Q | T Seyboth Wild | 7 | 6 | | | | | | | | | |
| Q | T Seyboth Wild | 5 | 7$^7$ | 7 | | | | | | Q | T Seyboth Wild | 3 | 1 | | | | |
| Alt | F Díaz Acosta | 4 | 4 | | | | | | | SE | M Navone | 6 | 6 | | | | |
| LL | C Sánchez Jover | 6 | 6 | | LL | C Sánchez Jover | 6 | 3 | 1 | | | | | | | | |
| SE | M Navone | 6 | 6 | | SE | M Navone | 4 | 6 | 6 | | | | | | | | |
| 6 | F Meligeni Alves | 2 | 4 | | | | | | | | | | | SE | M Navone | 3 | 5 |
| Q | H Casanova | 6 | 5 | 6 | | | | | | | | | | | JM Cerúndolo | 6 | 7 |
| | A Collarini | 4 | 7 | 3 | Q | H Casanova | 2 | 2 | | | | | | | | | |
| Q | N Álvarez | 3 | 3 | | | JM Cerúndolo | 6 | 6 | | | | | | | | | |
| | JM Cerúndolo | 6 | 6 | | | | | | | | JM Cerúndolo | 6 | 6 | | | | |
| | JB Torres | 7$^7$ | 3 | 6 | | | | | | 5 | F Bagnis | 4 | 2 | | | | |
| | GA Olivieri | 6$^1$ | 6 | 3 | | JB Torres | 1 | 4 | | | | | | | | | |
| | TA Tirante | 1 | 4 | | 5 | F Bagnis | 6 | 6 | | | | | | | | | |
| 5 | F Bagnis | 6 | 6 | | | | | | | | | | | | | | |

### Bottom half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 8 | Y Hanfmann | 6 | 6 | | | | | | | | | | | | | | | |
| Alt | G Villanueva | 2 | 4 | | 8 | Y Hanfmann | | | | | | | | | | | | |
| | N Kicker | 3 | 7 | 4 | | R Olivo | w/o | | | | | | | | | | | |
| | R Olivo | 6 | 5 | 6 | | | | | | | R Olivo | 3 | 6 | 2 | | | | |
| Q | Ignacio Monzón | 7 | 4 | 6$^4$ | | | | | | 4 | C Ugo Carabelli | 6 | 4 | 6 | | | | |
| WC | Juan Bautista Otegui | 5 | 6 | 7$^7$ | WC | JB Otegui | 2 | 6 | 4 | | | | | | | | | |
| | D Dutra da Silva | 2 | 2 | | 4 | C Ugo Carabelli | 6 | 0 | 6 | | | | | | | | | |
| 4 | C Ugo Carabelli | 6 | 6 | | | | | | | | | | | | 4 | C Ugo Carabelli | 6 | 6 |
| 7 | S Rodríguez Taverna | 6$^8$ | 6 | 5 | | | | | | | | | | | | D Popko | 2 | 1 |
| | D Popko | 7$^{10}$ | 0 | 7 | | D Popko | 6 | 6 | | | | | | | | | | |
| Q | Wilson Leite | 4 | 6 | 6 | Q | W Leite | 4 | 3 | | | | | | | | | | |
| WC | L Midón | 6 | 3 | 1 | | | | | | | D Popko | 7 | 0 | 6 | | | | |
| WC | RA Burruchaga | 6 | 6 | | | | | | | WC | RA Burruchaga | 5 | 6 | 2 | | | | |
| Q | Facundo Juárez | 3 | 3 | | WC | RA Burruchaga | 7$^8$ | 7 | | | | | | | | | | |
| | Pol Martín Tiffon | 4 | 3 | | 2 | D Altmaier | 6$^6$ | 5 | | | | | | | | | | |
| 2 | D Altmaier | 6 | 6 | | | | | | | | | | | | | | | |