# List of hospitals in South Carolina

List of hospitals in South Carolina (U.S. state), sorted by hospital name.
| Name | City | County | Hospital beds | Trauma designation | Affiliation | Notes |
| Abbeville Area Medical Center | Abbeville | Abbeville | 25 | — | — | |
| Aiken Regional Medical Center | Aiken | Aiken | 273 | — | UHS | |
| Allendale County Hospital | Fairfax | Allendale | 25 | — | — | |
| AnMed Health Cannon | Pickens | Pickens | 55 | — | AnMed | |
| AnMed Health Medical Center | Anderson | Anderson | 461 | Level III | AnMed | |
| AnMed Health Rehabilitation Hospital | Anderson | Anderson | 60 | | AnMed | |
| AnMed Health Women & Children's Hospital | Anderson | Anderson | 72 | — | AnMed | |
| Beaufort Memorial Hospital | Beaufort | Beaufort | 197 | Level III | — | |
| Bon Secours St. Francis Hospital | Charleston | Charleston | 200 | — | RSFH | |
| Carolina Center for Behavioral Health | Greer | | 138 | — | — | |
| Carolina Pines Regional Medical Center | Hartsville | Darlington | 116 | Level III | ScionHealth | |
| Cherokee Medical Center | Gaffney | Cherokee | 125 | — | SRHS | Formerly Novant Health Gaffney Medical Center and later Mary Black Health System - Gaffney |
| Coastal Carolina Hospital | Hardeeville | Jasper | 41 | — | Novant | |
| Colleton Medical Center | Walterboro | Colleton | 135 | — | HCA | |
| Columbia VA Health Care | Columbia | | 204 | — | VA | |
| ContinueCare Hospital | Columbia | | 35 | — | | |
| Conway Medical Center | Conway | Horry | 210 | — | — | |
| East Cooper Medical Center | Mount Pleasant | Charleston | 130 | Level III | Novant | |
| Edgefield County Hospital | Edgefield | Edgefield | 25 | — | — | |
| Grand Strand Medical Center | Myrtle Beach | Horry | 369 | Level I | HCA | |
| Hampton Regional Medical Center | Varnville | Hampton | 32 | — | — | |
| Hilton Head Hospital | Hilton Head Island | Beaufort | 109 | — | Novant | |
| Lexington Medical Center | West Columbia | Lexington | 508 | Level III | — | |
| McLeod Health Cheraw | Cheraw | Chesterfield | 59 | — | McLeod | Formerly Chesterfield General Hospital |
| McLeod Health Clarendon | Manning | Clarendon | 81 | — | McLeod | Formerly Clarendon Memorial Hospital |
| McLeod Health Darlington | Darlington | Darlington | 72 | — | McLeod | Formerly McLeod Medical Center - Darlington |
| McLeod Health Dillon | Dillon | Dillon | 79 | — | McLeod | Formerly McLeod Medical Center - Dillon |
| McLeod Health Loris | Loris | Horry | 50 | — | McLeod | Formerly McLeod Medical Center - Loris |
| McLeod Health Seacoast | Little River | Horry | 106 | — | McLeod | Formerly McLeod Medical Center - Seacoast |
| McLeod Regional Medical Center | Florence | Florence | 517 | Level II | McLeod | |
| MUSC Health Bamberg-Barnwell Emergency | Denmark | Bamberg | — | — | MUSC | Freestanding ED; no inpatient beds on site. |
| MUSC Health Black River Medical Center | Cades | Williamsburg | 25 | — | MUSC | |
| MUSC Health Chester Medical Center | Chester | Chester | 82 | — | MUSC | Formerly Chester Regional Medical Center |
| MUSC Health Columbia Medical Center Downtown | Columbia | Richland | 258 | — | MUSC | formerly Providence Health |
| MUSC Health Columbia Medical Center Northeast | Columbia | Richland | 74 | — | MUSC | Formerly Providence Health Northeast |
| MUSC Health Fairfield Emergency | Winnsboro | Fairfield | — | — | MUSC | Freestanding ED; no inpatient beds on site. formerly Providence Health Fairfield |
| MUSC Health Florence Medical Center | Florence | Florence | 310 or 396 | Level III | MUSC | Formerly Carolinas Hospital System |
| MUSC Health Kershaw Medical Center | Camden | Kershaw | 119 | — | MUSC | Formerly KershawHealth Medical Center |
| MUSC Health Lancaster Medical Center | Lancaster | Lancaster | 199 or 211 or 225 | — | MUSC | Formerly Springs Memorial Hospital |
| MUSC Health Marion Medical Center | Mullins | Marion | 124 | — | MUSC | Formerly Carolinas Hospital System - Marion |
| MUSC Health Orangeburg | Orangeburg | Orangeburg | 286 | Level III | MUSC | Formerly Regional Medical Center |
| MUSC Health University Medical Center | Charleston | Charleston | 728 | Level I | MUSC | Formerly Medical University of South Carolina Hospital |
| Newberry County Memorial Hospital | Newberry | Newberry | 90 | — | — | |
| Pelham Medical Center | Greer | Spartanburg | 48 | — | SRHS | |
| Piedmont Medical Center | Rock Hill | York | 288 | Level III | Tenet | |
| Piedmont Medical Center - Fort Mill | Fort Mill | York | 100 | — | Tenet | |
| Piedmont Medical Center - Gold Hill ED | Fort Mill | York | — | — | Tenet | Freestanding ED; no inpatient beds on site |
| Prisma Health Baptist Easley Hospital | Easley | Pickens | 109 | — | Prisma | |
| Prisma Health Baptist Hospital | Columbia | Richland | 352 | — | Prisma | |
| Prisma Health Baptist Parkridge Hospital | Columbia | Richland | 76 | — | Prisma | |
| Prisma Health Greenville Memorial Hospital | Greenville | Greenville | 864 | Level I | Prisma | |
| Prisma Health Greer Memorial Hospital | Greer | Greenville | 82 | Level III | Prisma | |
| Prisma Health Hillcrest Hospital | Simpsonville | Greenville | 43 | — | Prisma | |
| Prisma Health Laurens County Hospital | Clinton | Laurens | 76 | — | Prisma | |
| Prisma Health North Greenville Hospital | Travelers Rest | Greenville | 45 | — | Prisma | LTAC |
| Prisma Health Oconee Memorial Hospital | Seneca | Oconee | 169 | — | Prisma | |
| Prisma Health Patewood Hospital | Greenville | Greenville | 72 | — | Prisma | |
| Prisma Health Richland Hospital | Columbia | Richland | 641 | Level I | Prisma | |
| Prisma Health Tuomey Hospital | Sumter | Sumter | 283 | — | Prisma | |
| Ralph H. Johnson VA Medical Center | Charleston | Charleston | 152 | — | VA | |
| Regency Hospital of Florence | Florence | Florence | 40 | — | Select Medical | LTAC |
| Regency Hospital of Greenville | Greenville | Greenville | 32 | — | Select Medical | LTAC, located within St. Francis Hospital - Downtown |
| Roper Hospital | Charleston | Charleston | 334 | — | RSFH | |
| Roper St. Francis Berkeley Hospital | Summerville | Berkeley | 50 | | RSFH | |
| Roper St. Francis Mount Pleasant Hospital | Mount Pleasant | Charleston | 85 | — | RSFH | |
| Self Regional Healthcare | Greenwood | Greenwood | 322 or 358 | Level III | — | Formerly Self Memorial Hospital |
| Shriners Hospitals for Children - Greenville | Greenville | Greenville | 50 | — | — | |
| Spartanburg Hospital for Restorative Care | Spartanburg | Spartanburg | 97 | — | SRHS | |
| Spartanburg Medical Center | Spartanburg | Spartanburg | 540 | Level I | SRHS | |
| Spartanburg Medical Center Mary Black Campus | Spartanburg | Spartanburg | 207 | — | SRHS | Formerly Mary Black Health System - Spartanburg |
| St. Francis Downtown | Greenville | Greenville | 245 | — | Bon Secours | |
| St. Francis Eastside | Greenville | Greenville | 93 | — | Bon Secours | |
| Summerville Medical Center | Summerville | Dorchester | 124 | — | HCA Healthcare | |
| Tidelands Georgetown Memorial Hospital | Georgetown | Georgetown | 131 | — | Tidelands/MUSC | |
| Tidelands Waccamaw Community Hospital | Murrells Inlet | Georgetown | 124 | — | Tidelands/MUSC | |
| Trident Medical Center | North Charleston | Charleston | 321 | Level II | HCA Healthcare | |
| Union Medical Center | Union | Union | 85 | — | SRHS | |
| Closed - Williamsburg Regional Hospital | Kingstree | Williamsburg | 25 | — | — | Closed (date unknown) |
| Closed - Fairfield Memorial Hospital | Winnsboro | Fairfield | 25 | — | — | Closed Dec 18, 2018 |
| Closed - Southern Palmetto Hospital | Barnwell | Barnwell | 53 | — | — | Formerly Barnwell County Hospital; closed Jan 2016 |
| Closed - Lake City Community Hospital | Lake City | Florence | 48 | — | — | Closed Dec. 16 2022; replaced by MUSC Health Black River |