# List of number-one singles of 2021 (Portugal)

The Portuguese Singles Chart ranks the best-performing singles in Portugal, as compiled by the Associação Fonográfica Portuguesa.
| Week | Song | Artist |
| 1/2021 | "São Paulo" | Yuri Nr5 |
| 2/2021 | "Drivers License" | Olivia Rodrigo |
| 3/2021 | "Drivers License" | Olivia Rodrigo |
| 4/2021 | "Drivers License" | Olivia Rodrigo |
| 5/2021 | "Drivers License" | Olivia Rodrigo |
| 6/2021 | "Drivers License" | Olivia Rodrigo |
| 7/2021 | "Drivers License" | Olivia Rodrigo |
| 8/2021 | "Drivers License" | Olivia Rodrigo |
| 9/2021 | "Drivers License" | Olivia Rodrigo |
| 10/2021 | "Drivers License" | Olivia Rodrigo |
| 11/2021 | "Without You" | The Kid Laroi |
| 12/2021 | "Peaches" | Justin Bieber featuring Daniel Caesar and Giveon |
| 13/2021 | "Peaches" | Justin Bieber featuring Daniel Caesar and Giveon |
| 14/2021 | "Montero (Call Me by Your Name)" | Lil Nas X |
| 15/2021 | "Montero (Call Me by Your Name)" | Lil Nas X |
| 16/2021 | "Montero (Call Me by Your Name)" | Lil Nas X |
| 17/2021 | "Montero (Call Me by Your Name)" | Lil Nas X |
| 18/2021 | "Montero (Call Me by Your Name)" | Lil Nas X |
| 19/2021 | "Montero (Call Me by Your Name)" | Lil Nas X |
| 20/2021 | "Montero (Call Me by Your Name)" | Lil Nas X |
| 21/2021 | "Good 4 U" | Olivia Rodrigo |
| 22/2021 | "Good 4 U" | Olivia Rodrigo |
| 23/2021 | "Good 4 U" | Olivia Rodrigo |
| 24/2021 | "Bipolar" | MC Davi, MC Pedrinho and MC Don Juan |
| 25/2021 | "Bipolar" | MC Davi, MC Pedrinho and MC Don Juan |
| 26/2021 | "Bipolar" | MC Davi, MC Pedrinho and MC Don Juan |
| 27/2021 | "Beggin'" | Måneskin |
| 28/2021 | "Beggin'" | Måneskin |
| 29/2021 | "Beggin'" | Måneskin |
| 30/2021 | "Beggin'" | Måneskin |
| 31/2021 | "Industry Baby" | Lil Nas X and Jack Harlow |
| 32/2021 | "Industry Baby" | Lil Nas X and Jack Harlow |
| 33/2021 | "Industry Baby" | Lil Nas X and Jack Harlow |
| 34/2021 | "Industry Baby" | Lil Nas X and Jack Harlow |
| 35/2021 | "Industry Baby" | Lil Nas X and Jack Harlow |
| 36/2021 | "Pepas" | Farruko |
| 37/2021 | "Pepas" | Farruko |
| 38/2021 | "Industry Baby" | Lil Nas X and Jack Harlow |
| 39/2021 | "Love Nwantiti (Ah Ah Ah)" | CKay featuring Joeboy and Kuami Eugene |
| 40/2021 | "Love Nwantiti (Ah Ah Ah)" | CKay featuring Joeboy and Kuami Eugene |
| 41/2021 | "Love Nwantiti (Ah Ah Ah)" | CKay featuring Joeboy and Kuami Eugene |
| 42/2021 | "Love Nwantiti (Ah Ah Ah)" | CKay featuring Joeboy and Kuami Eugene |
| 43/2021 | "Love Nwantiti (Ah Ah Ah)" | CKay featuring Joeboy and Kuami Eugene |
| 44/2021 | "Love Nwantiti (Ah Ah Ah)" | CKay featuring Joeboy and Kuami Eugene |
| 45/2021 | "Love Nwantiti (Ah Ah Ah)" | CKay featuring Joeboy and Kuami Eugene |
| 46/2021 | "Love Nwantiti (Ah Ah Ah)" | CKay featuring Joeboy and Kuami Eugene |
| 47/2021 | "Love Nwantiti (Ah Ah Ah)" | CKay featuring Joeboy and Kuami Eugene |
| 48/2021 | "Love Nwantiti (Ah Ah Ah)" | CKay featuring Joeboy and Kuami Eugene |
| 49/2021 | "Love Nwantiti (Ah Ah Ah)" | CKay featuring Joeboy and Kuami Eugene |
| 50/2021 | "Love Nwantiti (Ah Ah Ah)" | CKay featuring Joeboy and Kuami Eugene |
| 51/2021 | "Love Nwantiti (Ah Ah Ah)" | CKay featuring Joeboy and Kuami Eugene |
| 52/2021 | "Love Nwantiti (Ah Ah Ah)" | CKay featuring Joeboy and Kuami Eugene |