# Geoffrey Bodenhausen

Geoffrey Bodenhausen (born 1951) is a French chemist specializing in nuclear magnetic resonance, being highly cited in his field. He is a Corresponding member of the Royal Netherlands Academy of Arts and Sciences and a Fellow of the American Physical Society. He is professeur émérite at the Department of Chemistry at the École Normale Supérieure (ENS) in Paris and professeur honoraire at the Laboratory of Biomolecular Magnetic Resonance of the École Polytechnique Fédérale de Lausanne (EPFL). He is a member of the editorial board of the journal Progress in Nuclear Magnetic Resonance Spectroscopy. He is the chair of the editorial board of the journal Magnetic Resonance.

## Education

He received a Diploma in chemistry from ETH Zurich in 1974, and a D.Phil. from Oxford University in 1977, supervised by Ray Freeman.

## Career

Bodenhausen began his post-doctoral research under the supervision of Robert and Regitze Vold at the University of California in San Diego. He subsequently worked as Research Staff with Leo Neuringer and Robert G. Griffin at the Massachusetts Institute of Technology and then in 1980 he moved to the ETH in Zurich, where he joined the group of Richard R. Ernst.
In 1985 he was appointed to a professorship at the University of Lausanne. In 1994 he became a professor at the Florida State University in Tallahassee filling the position of Director of the Institute for Advanced Studies in Magnetic Resonance. In 1996 he was elected fellow of the American Physical Society "for his numerous contributions toward making magnetic resonance one of the most sophisticated and versatile methods available for gaining insight into structure and dynamics of molecules in condensed and gas phase."
In 1996 he was awarded a professorship at the Ecole Normale Supérieure in Paris. He also held a part-time position at the University of Lausanne, and, after 2001, at the École Polytechnique Fédérale de Lausanne.
From 2005 to 2011 he chaired the Board of Trustees of EUROMAR.

## Research

Bodenhausen was one of the pioneers in the field of two-dimensional Fourier transform NMR spectroscopy. In the group of Ray Freeman he contributed to some of the first heteronuclear experiments.
In 1976 he contributed to a scheme to induce selective excitation of small portions of multiline spectra, later named DANTE by Morris and Freeman. He also analysed spin-echo spectra and rationalized the appearance of negative lines. He developed the first phase-cycle known as 'Exorcycle'.
In 1977 Bodenhausen and Freeman illustrated that it was possible to observe a spectrum of a heteronucleus (an atomic nucleus other than a proton) to achieve indirect detection of the proton resonance frequencies, and the correlations of chemical shifts between protons and heteronuclei. In 1980 Bodenhausen and D. J. Ruben introduced the HSQC (Heteronuclear Single Quantum Coherence) experiment, which produces sensitive two-dimensional (2D) spectra with one axis for protons ($^1$H) and the other for a heteronucleus, usually $^{13}$C or $^{15}$N. This double INEPT has been the base for many subsequent heteronuclear correlation experiments published in the literature and it has proven pivotal in the spectroscopy of organic chemistry and in the field of protein NMR.
One of the first steps in increasing the information content of NMR spectra was the introduction of a relayed coherence transfer by Geoffrey Bodenhausen together with Philip Bolton and Gerhard Eich.
In 1984 he published with Herbert Kogler and Richard R. Ernst a pivotal article in the Journal of Magnetic Resonance where they described how to design phase cycles allowing the selection of specific coherence-transfer pathways in NMR pulse experiments.
In 1987 he published with Richard R. Ernst and Alexander Wokaun Principles of Nuclear Magnetic Resonance in One and Two Dimensions, considered a classical monograph on the topic of multidimensional NMR.

## Honours and awards

* 1990: National Latsis Prize awarded by the Swiss National Science Foundation with support of the Latsis Foundation.
* 1993: PhD degree (Doctor honoris causa), University of Stockholm.
* 1996: Fellow of the American Physical Society.
* 1997: Corresponding member (Correspondent) of the Royal Netherlands Academy of Arts and Sciences.
* 2006: Catalan-Sabatier Prize of the Spanish Royal Society of Chemistry
* 2008: Fellow of the International Society for Magnetic Resonance.
* 2017: Chevalier de la Légion d'honneur (Knight of the French Legion of Honour)
* 2019: Günther Laukien Prize

## Books

* Bodenhausen, Geoffrey; Wokaun, Alexander (1987). Principles of Nuclear Magnetic Resonance in One and Two Dimension. Clarendon Press. p. 690. ISBN 9780198556473.

## Patents

* DE Patent 3839820, Lyndon Emsley & Geoffrey Bodenhausen, "Verfahren zum selektiven Anregen von nmr-Signalen", issued May 31, 1990
* DE Patent 3940633, Lyndon Emsley & Geoffrey Bodenhausen, "Gauss-Impuls-Kaskade", issued June 13, 1991
* US Patent 5327086, Geoffrey Bodenhausen; Jean-Marc Boehlen & Irene Burghardt, "Multiple-quantum NMR with frequency-modulated chirp pulses", issued July 5, 1994
* US Patent 2009039883, Geoffrey Bodenhausen; Paul Vasos & Riddhiman Sarkar, "Singlet-state exchange NMR spectroscopy for the study of very slow dynamic processes", issued February 12, 2009
* US Patent 2012286782, Sami Jannin; Aurelien Bornet & Geoffrey Bodenhausen, "Method for NMR spectroscopy with sustained induction decays of long-lived coherences", issued November 15, 2012
* US Patent 2013021031, Diego Carnvale & Geoffrey Bodenhausen, "Fourier Tickling For Homonuclear Decoupling in NMR"
* EP Patent 2786165, Geoffrey Bodenhausen; Aurelien Bornet & Roberto Buratto et al., "Method for the NMR based determination of the affinity of drugs for a target protein", issued December 8, 2014