# 2021 Major League Soccer season

The 2021 Major League Soccer season was the 26th season of Major League Soccer (MLS), the top professional soccer league in the United States and Canada. The 2021 season included the addition of Austin FC as an expansion club, which took the league to 27 teams.
Due to the ongoing COVID-19 pandemic, the season was originally scheduled to begin on April 3, as opposed to the normal late February or early March start. This was later pushed back to April 16, the latest ever start to an MLS season, due to negotiations with the MLS Players Association for a new collective bargaining agreement. The regular season concluded on November 7. The 2021 MLS Cup Playoffs began on November 20, and concluded with MLS Cup 2021 on December 11.
At the beginning of the season, COVID-19 cross-border restrictions imposed by the Canadian government has also made the Canadian teams to play their home matches in the United States from the start of the season, while also sharing stadiums with other American MLS teams. On July 14, MLS announced that a select Toronto FC and CF Montréal matches would be played in Canada while working with the Canadian government on how the matches were to be held. Nearly a week later, the MLS announced that the Canadian teams would play home matches in Canada in August 2021.
The Columbus Crew were the defending champions, having defeated Seattle Sounders FC in MLS Cup 2020 but was eliminated from playoffs during the regular season, while the Philadelphia Union were the defending Supporters' Shield winners. The New England Revolution won their first Supporters' Shield, in the process breaking the record for most regular season points collected. New York City FC won their first ever MLS Cup, beating Portland Timbers in the decider.

## Teams
### Stadiums and locations

| Team | Stadium | Capacity |
| Atlanta United FC | Mercedes-Benz Stadium | 71,000 |
| Austin FC | Q2 Stadium | 20,500 |
| Chicago Fire FC | Soldier Field | 24,955 |
| FC Cincinnati | TQL Stadium | 26,000 |
| Colorado Rapids | Dick's Sporting Goods Park | 18,061 |
| Columbus Crew | Lower.com Field | 20,011 |
| FC Dallas | Toyota Stadium | 20,500 |
| D.C. United | Audi Field | 20,000 |
| Houston Dynamo FC | BBVA Stadium | 22,039 |
| LA Galaxy | Dignity Health Sports Park | 27,000 |
| Los Angeles FC | Banc of California Stadium | 22,000 |
| Minnesota United FC | Allianz Field | 19,400 |
| Inter Miami CF | DRV PNK Stadium | 18,000 |
| CF Montréal | Saputo Stadium | 19,619 |
| Nashville SC | Nissan Stadium | 27,600 |
| New England Revolution | Gillette Stadium | 20,000 |
| New York City FC | Yankee Stadium | 30,321 |
| New York Red Bulls | Red Bull Arena | 25,000 |
| Orlando City SC | Exploria Stadium | 25,500 |
| Philadelphia Union | Subaru Park | 18,500 |
| Portland Timbers | Providence Park | 25,218 |
| Real Salt Lake | Rio Tinto Stadium | 20,213 |
| San Jose Earthquakes | PayPal Park | 18,000 |
| Seattle Sounders FC | Lumen Field | 37,722 |
| Sporting Kansas City | Children's Mercy Park | 18,467 |
| Toronto FC | BMO Field | 28,351 |
| Vancouver Whitecaps FC | BC Place | 22,120 |
* ^ Non-soccer specific stadium and artificially reduced capacity.
* ^ Some of the home matches were played at Red Bull Arena at Harrison due to scheduling conflicts at Yankee Stadium.
* ^ Temporary stadium.
* ^ CF Montréal played at DRV PNK Stadium, Fort Lauderdale since the start of the season due to COVID-19 travel restrictions in Canada before returning to playing home matches in Montreal on July 17. A small number of matches were also played in different stadiums due to scheduling conflicts with the 2021 CONCACAF Gold Cup qualification.
* ^ Toronto FC played at Exploria Stadium, Orlando from the start of the season due to COVID-19 travel restrictions in Canada before returning playing home matches in Toronto on July 17.
* ^ Vancouver Whitecaps FC played at Rio Tinto Stadium, Sandy for the start of the season due to COVID-19 travel restrictions in Canada before returning playing home matches in Vancouver on August 21.
* ^ Columbus Crew played at Historic Crew Stadium from the start of the season before moving into Lower.com Field on July 3.

### Personnel and sponsorship

Note: All teams use Adidas as universal kit manufacturer.
| Team | Head coach | Captain | Shirt sponsor | Sleeve sponsor |
| Atlanta United FC | Gonzalo Pineda | Brad Guzan | American Family Insurance | AT&T, Piedmont Orthopedics |
| Austin FC | Josh Wolff | Alexander Ring | Yeti | Netspend |
| Chicago Fire FC | Frank Klopas (interim) | Francisco Calvo | Motorola | CIBC |
| FC Cincinnati | Tyrone Marshall (interim) | Luciano Acosta | Mercy Health | Kroger |
| Colorado Rapids | Robin Fraser | Jack Price | — | — |
| Columbus Crew | Caleb Porter | Jonathan Mensah | Nationwide | Scotts |
| D.C. United | Hernán Losada | Steve Birnbaum | Leidos | EagleBank |
| FC Dallas | Marco Ferruzzi (interim) | Matt Hedges | MTX Group | AdvoCare |
| Houston Dynamo FC | Tabare Ramos | Timothy Parker | MD Anderson | Kroger, Coushatta Casino Resort |
| Inter Miami CF | Phil Neville | Gregore | XBTO | Baptist Health |
| LA Galaxy | Greg Vanney | Jonathan dos Santos | Herbalife | Honey |
| Los Angeles FC | Bob Bradley | Carlos Vela | Flex | Target, Postmates |
| Minnesota United FC | Adrian Heath | Osvaldo Alonso | Target | Bell Bank |
| CF Montréal | Wilfried Nancy | Samuel Piette | Bank of Montreal | Saputo, Jason |
| Nashville SC | Gary Smith | Dax McCarty | Renasant Bank | Hyundai |
| New England Revolution | Bruce Arena | Carles Gil | UnitedHealth | Santander |
| New York City FC | Ronny Deila | Sean Johnson | Etihad Airways | Sol Cacao |
| New York Red Bulls | Gerhard Struber | Sean Davis | Red Bull | Provident Bank |
| Orlando City SC | Óscar Pareja | Nani | Orlando Health | Exploria |
| Philadelphia Union | Jim Curtin | Alejandro Bedoya | Bimbo Bakeries USA | Subaru |
| Portland Timbers | Giovanni Savarese | Diego Valeri | Alaska Airlines | TikTok |
| Real Salt Lake | Pablo Mastroeni (interim) | Albert Rusnák | LifeVantage | KeyBank, Ford |
| San Jose Earthquakes | Matías Almeyda | Chris Wondolowski | Intermedia | PayPal |
| Seattle Sounders FC | Brian Schmetzer | Nicolás Lodeiro | Zulily | Emerald Queen Casino |
| Sporting Kansas City | Peter Vermes | Johnny Russell | Victory Project | Compass Minerals, Children's Mercy |
| Toronto FC | Javier Pérez | Michael Bradley | Bank of Montreal | GE Appliances, Canadian Tire |
| Vancouver Whitecaps FC | Vanni Sartini (interim) | Russell Teibert | Bell Canada | — |

### Coaching changes

| Team | Outgoing coach | Manner of departure | Date of vacancy | Position in table | Incoming coach | Date of appointment |
| Toronto FC | Greg Vanney | Resigned | December 1, 2020 | Pre-season | Chris Armas | January 13, 2021 |
| D.C. United | Chad Ashton | End of interim period | December 12, 2020 | Pre-season | Hernán Losada | January 18, 2021 |
| LA Galaxy | Dominic Kinnear | End of interim period | December 12, 2020 | Pre-season | Greg Vanney | January 5, 2021 |
| Atlanta United FC | Stephen Glass | End of interim period | December 16, 2020 | Pre-season | Gabriel Heinze | December 18, 2020 |
| Inter Miami CF | Diego Alonso | Mutual consent | January 7, 2021 | Pre-season | Phil Neville | January 18, 2021 |
| CF Montréal | Thierry Henry | Resigned | February 25, 2021 | Pre-season | Wilfried Nancy | March 8, 2021 |
| Toronto FC | Chris Armas | Fired | July 4, 2021 | 14th in East, 27th overall | Javier Pérez | July 4, 2021 |
| Atlanta United FC | Gabriel Heinze | Fired | July 18, 2021 | 10th in East, 20th Overall | Rob Valentino (interim) | July 18, 2021 |
| Atlanta United FC | Rob Valentino | End of interim period | August 12, 2021 | 10th in East, 20th Overall | Gonzalo Pineda | August 12, 2021 |
| Real Salt Lake | Freddy Juarez | Mutual consent | August 27, 2021 | 6th in West, 13th overall | Pablo Mastroeni (interim) | August 27, 2021 |
| Vancouver Whitecaps FC | Marc Dos Santos | Mutual consent | August 27, 2021 | 10th in West, 19th overall | Vanni Sartini (interim) | August 27, 2021 |
| FC Dallas | Luchi Gonzalez | Fired | September 19, 2021 | 11th in West, 21st overall | Marco Ferruzzi (interim) | September 19, 2021 |
| FC Cincinnati | Jaap Stam | Fired | September 27, 2021 | 13th in East, 26th overall | Tyrone Marshall (interim) | September 27, 2021 |
| Chicago Fire FC | Raphaël Wicky | Mutual consent | September 30, 2021 | 12th in East, 22nd overall | Frank Klopas (interim) | September 30, 2021 |
| Houston Dynamo FC | Tab Ramos | Fired | November 4, 2021 | 13th in West, 25th overall | Vacant until next season | Vacant until next season |
| Los Angeles FC | Bob Bradley | Mutual consent | November 18, 2021 | Post-season | Vacant until next season | Vacant until next season |
* ↑ Pérez was initially appointed as interim manager, but the move was made permanent on August 9, 2021.

## Regular season
### Format

Each team played 34 matches, including 17 home games and 17 away games. Due to the difference in the number of teams in each conference, each conference had its own schedule construction format:
* All 14 Eastern Conference teams played six regional Eastern Conference opponents three times and the remaining seven Eastern Conference opponents twice. Each of them also played two cross conference games against different opponents.
* 11 out of the 13 Western Conference teams played eight regional Western Conference opponents three times and the remaining four Western Conference opponents twice. Each of them also played two cross conference games against different opponents.
* The remaining two teams from the Western Conference played seven Western Conference opponents three times and the remaining five Western Conference opponents twice. Each of them also played three cross conference games against different opponents.

### Conference standings
#### Eastern Conference

| Pos | Teamvte | Pld | W | L | T | GF | GA | GD | Pts | Qualification |
| 1 | New England Revolution | 34 | 22 | 5 | 7 | 65 | 41 | +24 | 73 | Qualification for the playoffs conference semifinals and CONCACAF Champions League |
| 2 | Philadelphia Union | 34 | 14 | 8 | 12 | 48 | 35 | +13 | 54 | Qualification for the playoffs first round |
| 3 | Nashville SC | 34 | 12 | 4 | 18 | 55 | 33 | +22 | 54 | Qualification for the playoffs first round |
| 4 | New York City FC (C) | 34 | 14 | 11 | 9 | 56 | 36 | +20 | 51 | Qualification for the playoffs first round and CONCACAF Champions League |
| 5 | Atlanta United FC | 34 | 13 | 9 | 12 | 45 | 37 | +8 | 51 | Qualification for the playoffs first round |
| 6 | Orlando City SC | 34 | 13 | 9 | 12 | 50 | 48 | +2 | 51 | Qualification for the playoffs first round |
| 7 | New York Red Bulls | 34 | 13 | 12 | 9 | 39 | 33 | +6 | 48 | Qualification for the playoffs first round |
| 8 | D.C. United | 34 | 14 | 15 | 5 | 56 | 54 | +2 | 47 | |
| 9 | Columbus Crew | 34 | 13 | 13 | 8 | 46 | 45 | +1 | 47 | |
| 10 | CF Montréal | 34 | 12 | 12 | 10 | 46 | 44 | +2 | 46 | Qualification for the CONCACAF Champions League |
| 11 | Inter Miami CF | 34 | 12 | 17 | 5 | 36 | 53 | −17 | 41 | |
| 12 | Chicago Fire FC | 34 | 9 | 18 | 7 | 36 | 54 | −18 | 34 | |
| 13 | Toronto FC | 34 | 6 | 18 | 10 | 39 | 66 | −27 | 28 | |
| 14 | FC Cincinnati | 34 | 4 | 22 | 8 | 37 | 74 | −37 | 20 | |
* ↑ As MLS Cup 2021 champions
* 1 2 Canadian clubs cannot qualify for the 2022 CONCACAF Champions League through the MLS regular season or playoffs.
* ↑ As 2021 Canadian Championship winners

#### Western Conference

| Pos | Teamvte | Pld | W | L | T | GF | GA | GD | Pts | Qualification |
| 1 | Colorado Rapids | 34 | 17 | 7 | 10 | 51 | 35 | +16 | 61 | Qualification for the Playoffs Conference semifinals and CONCACAF Champions League |
| 2 | Seattle Sounders FC | 34 | 17 | 8 | 9 | 53 | 33 | +20 | 60 | Qualification for the Playoffs first round and CONCACAF Champions League |
| 3 | Sporting Kansas City | 34 | 17 | 10 | 7 | 58 | 40 | +18 | 58 | Qualification for the Playoffs first round |
| 4 | Portland Timbers | 34 | 17 | 13 | 4 | 56 | 52 | +4 | 55 | Qualification for the Playoffs first round |
| 5 | Minnesota United FC | 34 | 13 | 11 | 10 | 42 | 44 | −2 | 49 | Qualification for the Playoffs first round |
| 6 | Vancouver Whitecaps FC | 34 | 12 | 9 | 13 | 45 | 45 | 0 | 49 | Qualification for the Playoffs first round |
| 7 | Real Salt Lake | 34 | 14 | 14 | 6 | 55 | 54 | +1 | 48 | Qualification for the Playoffs first round |
| 8 | LA Galaxy | 34 | 13 | 12 | 9 | 50 | 54 | −4 | 48 | |
| 9 | Los Angeles FC | 34 | 12 | 13 | 9 | 53 | 51 | +2 | 45 | |
| 10 | San Jose Earthquakes | 34 | 10 | 13 | 11 | 46 | 54 | −8 | 41 | |
| 11 | FC Dallas | 34 | 7 | 15 | 12 | 47 | 56 | −9 | 33 | |
| 12 | Austin FC | 34 | 9 | 21 | 4 | 35 | 56 | −21 | 31 | |
| 13 | Houston Dynamo FC | 34 | 6 | 16 | 12 | 36 | 54 | −18 | 30 | |
* ↑ Canadian clubs cannot qualify for the 2022 CONCACAF Champions League through the MLS regular season or playoffs.

### Overall table

The leading team in this table wins the Supporters' Shield.
| Pos | Teamvte | Pld | W | L | T | GF | GA | GD | Pts | Qualification |
| 1 | New England Revolution (S) | 34 | 22 | 5 | 7 | 65 | 41 | +24 | 73 | CONCACAF Champions League |
| 2 | Colorado Rapids | 34 | 17 | 7 | 10 | 51 | 35 | +16 | 61 | CONCACAF Champions League |
| 3 | Seattle Sounders FC | 34 | 17 | 8 | 9 | 53 | 33 | +20 | 60 | CONCACAF Champions League |
| 4 | Sporting Kansas City | 34 | 17 | 10 | 7 | 58 | 40 | +18 | 58 | |
| 5 | Portland Timbers | 34 | 17 | 13 | 4 | 56 | 52 | +4 | 55 | |
| 6 | Philadelphia Union | 34 | 14 | 8 | 12 | 48 | 35 | +13 | 54 | |
| 7 | Nashville SC | 34 | 12 | 4 | 18 | 55 | 33 | +22 | 54 | |
| 8 | New York City FC (C) | 34 | 14 | 11 | 9 | 56 | 36 | +20 | 51 | CONCACAF Champions League |
| 9 | Atlanta United FC | 34 | 13 | 9 | 12 | 45 | 37 | +8 | 51 | |
| 10 | Orlando City SC | 34 | 13 | 9 | 12 | 50 | 48 | +2 | 51 | |
| 11 | Minnesota United FC | 34 | 13 | 11 | 10 | 42 | 44 | −2 | 49 | |
| 12 | Vancouver Whitecaps FC | 34 | 12 | 9 | 13 | 45 | 45 | 0 | 49 | |
| 13 | Real Salt Lake | 34 | 14 | 14 | 6 | 55 | 54 | +1 | 48 | |
| 14 | New York Red Bulls | 34 | 13 | 12 | 9 | 39 | 33 | +6 | 48 | |
| 15 | LA Galaxy | 34 | 13 | 12 | 9 | 50 | 54 | −4 | 48 | |
| 16 | D.C. United | 34 | 14 | 15 | 5 | 56 | 54 | +2 | 47 | |
| 17 | Columbus Crew | 34 | 13 | 13 | 8 | 46 | 45 | +1 | 47 | |
| 18 | CF Montréal | 34 | 12 | 12 | 10 | 46 | 44 | +2 | 46 | CONCACAF Champions League |
| 19 | Los Angeles FC | 34 | 12 | 13 | 9 | 53 | 51 | +2 | 45 | |
| 20 | Inter Miami CF | 34 | 12 | 17 | 5 | 36 | 53 | −17 | 41 | |
| 21 | San Jose Earthquakes | 34 | 10 | 13 | 11 | 46 | 54 | −8 | 41 | |
| 22 | Chicago Fire FC | 34 | 9 | 18 | 7 | 36 | 54 | −18 | 34 | |
| 23 | FC Dallas | 34 | 7 | 15 | 12 | 47 | 56 | −9 | 33 | |
| 24 | Austin FC | 34 | 9 | 21 | 4 | 35 | 56 | −21 | 31 | |
| 25 | Houston Dynamo FC | 34 | 6 | 16 | 12 | 36 | 54 | −18 | 30 | |
| 26 | Toronto FC | 34 | 6 | 18 | 10 | 39 | 66 | −27 | 28 | |
| 27 | FC Cincinnati | 34 | 4 | 22 | 8 | 37 | 74 | −37 | 20 | |

### Fixtures and results

All cross-conference matches are shown on the Eastern Conference table. In some cases, a team hosted another more than once; in this case, the first matchup is listed on top and the second is listed below.

#### Eastern Conference

| Home \ Away | ATL | CHI | CIN | CLB | DCU | MIA | MTL | NSH | NE | NYC | RBNY | ORL | PHI | TOR | CCH | CCA |
| Atlanta United FC | — | 3–1 | 4–0 | 0–1 | 3–2 | 1–0 | 1–0 | 2–2 | 0–1 | 1–1 | 0–0 | 3–0 | 2–2 | 1–0 | LAFC | SEA |
| — | — | — | — | — | 2–1 | — | 0–2 | — | — | — | — | — | 1–1 | 1–0 | 1–1 |
| Chicago Fire FC | 3–0 | — | 0–1 | 1–0 | 2–2 | 1–0 | 0–1 | 0–0 | 2–2 | 0–0 | 2–1 | 3–1 | 0–2 | 1–2 | RSL | SKC |
| — | — | — | — | — | — | — | — | 2–3 | 2–0 | — | — | 3–3 | — | 1–0 | 0–2 |
| FC Cincinnati | 1–1 | 3–4 | — | 2–2 | 0–0 | 2–3 | 0–0 | 3–6 | 0–1 | 1–2 | 0–1 | 1–1 | 1–2 | 2–0 | COL | HOU |
| 1–2 | — | — | — | — | 0–1 | — | — | — | — | — | 0–1 | — | — | 0–2 | 1–1 |
| Columbus Crew | 2–3 | 2–0 | 3–2 | — | 3–1 | 4–0 | 2–1 | 0–0 | 2–2 | 2–1 | 2–1 | 3–2 | 0–0 | 2–1 | SEA | ATX |
| — | 2–0 | — | — | 2–4 | — | — | — | — | — | 1–2 | — | — | — | 1–2 | 0–0 |
| D.C. United | 1–2 | 1–0 | 4–2 | 1–3 | — | 1–0 | 2–1 | 0–0 | 2–3 | 2–1 | 1–0 | 0–1 | 0–1 | 7–1 | MIN | SJ |
| — | 3–0 | — | — | — | — | — | — | — | — | 1–0 | — | 3–1 | — | 3–1 | 1–4 |
| Inter Miami CF | 1–1 | 3–2 | 5–1 | 1–0 | 0–3 | — | 0–2 | 2–1 | 0–5 | 1–3 | 0–4 | 1–2 | 1–1 | 3–1 | LA | POR |
| — | — | — | — | — | — | 2–1 | 1–5 | — | — | — | — | — | 3–0 | 2–3 | 0–1 |
| CF Montréal | 2–2 | 2–0 | 1–2 | 0–0 | 0–0 | 1–0 | — | 0–1 | 1–4 | 2–1 | 2–1 | 0–2 | 2–2 | 4–2 | HOU | VAN |
| 2–1 | — | 5–4 | — | — | — | — | — | — | — | — | — | — | 3–1 | 2–0 | 0–2 |
| Nashville SC | 2–2 | 5–1 | 2–2 | 1–1 | 5–2 | 0–0 | 2–2 | — | 2–0 | 3–1 | 1–1 | 1–1 | 1–0 | 3–2 | ATX | RSL |
| — | — | 3–0 | — | — | — | 1–1 | — | — | — | — | 2–2 | — | — | 1–0 | 0–0 |
| New England Revolution | 2–1 | 2–2 | 4–1 | 1–0 | 1–0 | 0–1 | 2–1 | 0–0 | — | 2–1 | 3–1 | 2–1 | 2–1 | 2–3 | COL | DAL |
| — | — | — | 1–1 | 3–2 | — | — | — | — | — | 3–2 | — | — | — | 1–0 | 1–2 |
| New York City FC | 1–0 | 1–0 | 5–0 | 1–2 | 2–1 | 2–0 | 1–0 | 0–0 | 2–3 | — | 0–1 | 5–0 | 1–1 | 1–1 | DAL | LAFC |
| — | — | — | 4–1 | 6–0 | — | — | — | 2–0 | — | — | — | — | — | 3–3 | 1–2 |
| New York Red Bulls | 0–0 | 2–0 | 0–0 | 1–0 | 1–1 | 1–0 | 1–0 | 2–0 | 2–3 | 1–1 | — | 2–1 | 1–1 | 2–0 | SKC | LA |
| — | 0–1 | — | — | — | — | — | — | — | 1–0 | — | — | 1–1 | — | 1–2 | 2–3 |
| Orlando City SC | 0–0 | 1–0 | 3–0 | 3–2 | 2–1 | 1–1 | 2–4 | 1–1 | 2–2 | 1–1 | 1–2 | — | 2–1 | 1–0 | SJ | SKC |
| 3–2 | — | — | — | — | 0–0 | 1–1 | — | — | — | — | — | — | — | 5–0 | 1–1 |
| Philadelphia Union | 1–0 | 1–1 | 2–0 | 1–0 | 2–1 | 1–2 | 1–1 | 1–0 | 1–1 | 0–2 | 1–0 | 3–1 | — | 3–0 | POR | MIN |
| — | — | — | 3–0 | — | — | — | — | 0–1 | 1–0 | — | — | — | — | 3–0 | 2–3 |
| Toronto FC | 0–2 | 3–1 | 0–2 | 2–0 | 1–3 | 0–1 | 1–1 | 1–1 | 1–2 | 2–2 | 1–1 | 2–3 | 2–2 | — | VAN | COL |
| — | — | 3–2 | — | — | — | — | 2–1 | — | — | — | 1–1 | — | — | 2–2 | 0–0 |

#### Western Conference

| Home \ Away | ATX | COL | DAL | HOU | LA | LAFC | MIN | POR | RSL | SJ | SEA | SKC | VAN |
| Austin FC | — | 0–1 | 3–5 | 3–2 | 2–0 | 0–2 | 0–1 | 4–1 | 2–1 | 0–0 | 0–1 | 3–1 | 1–2 |
| — | — | — | 2–1 | — | 1–2 | — | 3–1 | — | 3–4 | — | — | — |
| Colorado Rapids | 1–3 | — | 3–0 | 3–1 | 1–1 | 5–2 | 3–2 | 2–0 | 2–1 | 1–1 | 1–1 | 0–0 | 1–1 |
| 3–0 | — | 2–0 | — | — | — | 2–0 | — | — | — | 1–1 | — | — |
| FC Dallas | 2–0 | 0–0 | — | 1–1 | 4–0 | 2–3 | 1–1 | 4–1 | 2–2 | 1–1 | 0–1 | 0–2 | 2–2 |
| 2–1 | — | — | — | — | — | 0–0 | — | 1–2 | — | — | 1–3 | — |
| Houston Dynamo FC | 3–0 | 1–3 | 2–2 | — | 0–3 | 1–1 | 1–2 | 2–2 | 0–0 | 2–1 | 2–1 | 1–0 | 2–1 |
| — | 0–1 | 3–2 | — | — | — | — | 0–2 | — | — | — | — | 0–0 |
| LA Galaxy | 2–0 | 1–2 | 3–1 | 1–1 | — | 2–1 | 3–3 | 4–1 | 1–0 | 1–0 | 1–2 | 0–2 | 1–1 |
| — | — | 2–2 | — | — | 1–1 | — | 2–1 | — | 1–2 | — | — | — |
| Los Angeles FC | 2–0 | 2–1 | 2–0 | 1–1 | 3–3 | — | 2–2 | 1–2 | 2–1 | 3–1 | 1–1 | 1–4 | 2–2 |
| — | — | — | — | — | — | — | — | 3–2 | — | 3–0 | 4–0 | 1–1 |
| Minnesota United FC | 0–1 | 1–3 | 1–0 | 2–0 | 0–1 | 1–1 | — | 2–1 | 1–2 | 2–2 | 1–0 | 0–0 | 1–0 |
| 2–0 | — | — | 2–0 | 3–0 | — | — | — | — | — | — | 2–1 | — |
| Portland Timbers | 3–0 | 2–2 | 1–0 | 2–1 | 3–0 | 2–1 | 0–1 | — | 3–2 | 1–1 | 1–2 | 2–1 | 2–3 |
| — | — | — | — | — | 2–1 | — | — | 6–1 | 2–0 | 2–6 | — | — |
| Real Salt Lake | 1–0 | 3–0 | 3–2 | 1–1 | 2–2 | 0–1 | 1–1 | 1–3 | — | 1–2 | 1–0 | 3–1 | 3–1 |
| — | 3–1 | — | 2–1 | 2–1 | — | — | — | — | 3–4 | — | — | — |
| San Jose Earthquakes | 4–0 | 0–1 | 3–1 | 1–1 | 1–3 | 2–1 | 1–1 | 0–2 | 3–4 | — | 0–1 | 1–3 | 0–0 |
| — | — | 1–1 | — | — | 2–0 | — | — | — | — | 1–3 | — | 1–1 |
| Seattle Sounders FC | 0–0 | 3–0 | 1–1 | 2–0 | 3–0 | 2–0 | 4–0 | 0–2 | 2–1 | 0–1 | — | 1–3 | 2–2 |
| — | — | — | — | 1–1 | — | 1–0 | — | — | — | — | 1–2 | 4–1 |
| Sporting Kansas City | 2–1 | 3–1 | 1–2 | 3–2 | 2–0 | 2–1 | 4–0 | 1–1 | 0–1 | 1–1 | 1–2 | — | 3–0 |
| 1–1 | 1–1 | — | 4–2 | — | — | — | — | — | — | — | — | — |
| Vancouver Whitecaps FC | 2–1 | 0–1 | 1–0 | 0–0 | 1–2 | 2–1 | 2–2 | 1–0 | 0–4 | 3–0 | 1–1 | 2–1 | — |
| — | — | — | — | 2–1 | — | 2–1 | 0–1 | 4–1 | — | — | — | — |

### MLS All-Star Game
## MLS Cup Playoffs
### Bracket

| First round November 20–21, 23 | First round November 20–21, 23 | First round November 20–21, 23 | | | Conference semifinals November 25, 28, 30 | Conference semifinals November 25, 28, 30 | Conference semifinals November 25, 28, 30 | Conference finals December 4–5 | Conference finals December 4–5 | Conference finals December 4–5 | | MLS Cup December 11 | MLS Cup December 11 | MLS Cup December 11 |
| | | | | | E1 | New England Revolution | 2 (3) | | | | | | | |
| | | | | | E4 | New York City FC (p) | 2 (5) | | | | | | | |
| E4 | New York City FC | 2 | | | E4 | New York City FC (p) | 2 (5) | | | | | | | |
| E5 | Atlanta United FC | 0 | | | | | | | | | | | | |
| E5 | Atlanta United FC | 0 | | | | | | E4 | New York City FC | 2 | | | | |
| Eastern Conference | Eastern Conference | Eastern Conference | Eastern Conference | Eastern Conference | Eastern Conference | Eastern Conference | Eastern Conference | E4 | New York City FC | 2 | | | | |
| Eastern Conference | Eastern Conference | Eastern Conference | Eastern Conference | Eastern Conference | Eastern Conference | Eastern Conference | Eastern Conference | E2 | Philadelphia Union | 1 | | | | |
| E3 | Nashville SC | 3 | | | | | | | | | E2 | Philadelphia Union | 1 | |
| E6 | Orlando City SC | 1 | | | | | | | | | | | | |
| E6 | Orlando City SC | 1 | | | E3 | Nashville SC | 1 (0) | | | | | | | |
| | | | | | E2 | Philadelphia Union (p) | 1 (2) | | | | | | | |
| E2 | Philadelphia Union (a.e.t.) | 1 | | | E2 | Philadelphia Union (p) | 1 (2) | | | | | | | |
| E7 | New York Red Bulls | 0 | | | | | | | | | | | | |
| E7 | New York Red Bulls | 0 | | | | | | | | | | E4 | New York City FC (p) | 1 (4) |
| | | | | | | | | | | | | W4 | Portland Timbers | 1 (2) |
| | | | | | W1 | Colorado Rapids | 0 | | | | | | | |
| | | | | | W4 | Portland Timbers | 1 | | | | | | | |
| W4 | Portland Timbers | 3 | | | W4 | Portland Timbers | 1 | | | | | | | |
| W5 | Minnesota United FC | 1 | | | | | | | | | | | | |
| W5 | Minnesota United FC | 1 | | | | | | W4 | Portland Timbers | 2 | | | | |
| Western Conference | Western Conference | Western Conference | Western Conference | Western Conference | Western Conference | Western Conference | Western Conference | W4 | Portland Timbers | 2 | | | | |
| Western Conference | Western Conference | Western Conference | Western Conference | Western Conference | Western Conference | Western Conference | Western Conference | W7 | Real Salt Lake | 0 | | | | |
| W3 | Sporting Kansas City | 3 | | | | | | | | | W7 | Real Salt Lake | 0 | |
| W6 | Vancouver Whitecaps FC | 1 | | | | | | | | | | | | |
| W6 | Vancouver Whitecaps FC | 1 | | | W3 | Sporting Kansas City | 1 | | | | | | | |
| | | | | | W7 | Real Salt Lake | 2 | | | | | | | |
| W2 | Seattle Sounders FC | 0 (5) | | | W7 | Real Salt Lake | 2 | | | | | | | |
| W7 | Real Salt Lake (p) | 0 (6) | | | | | | | | | | | | |
Note: The higher seeded teams hosted matches, with the MLS Cup host determined by overall points.

## COVID-19 restrictions

From the start of the season, all Canadian teams played home matches behind closed doors at venues in a U.S. market (notwithstanding any local regulations otherwise allowing spectators) due to Canadian border restrictions.
On July 14, MLS announced that both CF Montreal and Toronto FC planned to return to playing matches at their home stadiums beginning July 17, citing new policies allowing vaccinated individuals to enter the country without 14 days self-isolation, provided that they test negative on a COVID-19 test. Unvaccinated individuals must still self-isolate, but a member of the MLS Players Association stated that nearly 95% of the league's player pool had been vaccinated, and Toronto FC manager Ali Curtis stated that all but two of their players were fully vaccinated. Toronto FC planned to admit 7,000 essential workers for the first match before expanding to 15,000 for subsequent matches, and CF Montreal planned to admit 5,000. However, Sportsnet reported that the plans had not yet been formally approved by the Public Health Agency of Canada, and that the Canadian government was expected to issue a statement on the matter.
| Team | Spectators | Limitations |
| Austin FC | All | All Home matches starting with the first home match at Q2 Stadium scheduled for June 19, 2021 to be operated at full capacity |
| Atlanta United FC | All | Capped at 50% (about 22,000 fans) capacity at start of season. Operating at full capacity since May 15, 2021. |
| Chicago Fire FC | All | Capped at 25% (about 15,500 fans) capacity from start of season. |
| FC Cincinnati | All | First home match at TQL Stadium was held on May 16, 2021. Capped up to 6,000 fans since the home opening match. Operating at full capacity since May 24, 2021. |
| Colorado Rapids | All | Capped at 44% (about 7,900 fans) capacity from start of season. |
| Columbus Crew | All | Capped at 30% (about 6,000 fans) capacity from start of season at Historic Crew Stadium. Operating at full capacity since June 20, 2021, including at Lower.com Field. |
| D.C. United | All | Capped at 25% (about 5,000 fans) capacity from start of season. Operating at full capacity since June 20, 2021. |
| FC Dallas | All | Capped at 50% (about 9,000 fans) capacity from start of season. Plans to have full capacity starting June 1, 2021. |
| Houston Dynamo FC | All | Capped at 30% (about 6,200 fans) capacity from start of season. |
| Inter Miami CF | All | Capped at 45% (about 8,000 fans) capacity for the first 3 matches of the season. Current plan is to host 16,000 fans starting May 29. |
| LA Galaxy | All | Allowed at least 100 spectators per match. Operating at full capacity since June 19. |
| Los Angeles FC | All | Currently allow at least 100 spectators per match. Operating at full capacity since June 19, 2021. |
| Minnesota United FC | All | Capped at 25% (about 5,000 fans) capacity from start of season. |
| CF Montréal | Some | Home matches played at DRV PNK Stadium in Fort Lauderdale and in other stadiums were played without any audience. All home matches played at Saputo Stadium since July 17 are currently capped at 5,000 fans. |
| Nashville SC | All | Capped at 40% (about 27,600 fans) capacity from start of season. |
| New England Revolution | All | Capped at 12% (about 7,900 fans) capacity from start of season. |
| New York City FC | All | Capped at 20% (about 10,800 fans) capacity from start of season. Negative COVID-19 PCR test within past 72 hours, negative COVID-19 rapid antigen test within past 6 hours, or vaccination completed no fewer than 14 days prior to the game required to enter for home matches at Yankee Stadium; although this is no longer a requirement since June 15, 2021. Capacity for home matches at Red Bull Arena will also be capped at 15%. |
| New York Red Bulls | All | Capped at 15% (about 3,750 fans) capacity from start of season. |
| Orlando City SC | All | Capped at 50% (about 12,750 fans) capacity from start of season. Opened to 100% capacity beginning June 22. |
| Philadelphia Union | All | Capped at 30% (about 5,000 fans) capacity from start of season. |
| Portland Timbers | All | Capped at 25% (about 6,300 fans) capacity from start of season. Starting June 19, the Timbers will allow 80% capacity with spectators 16 and over required to be fully vaccinated. |
| Real Salt Lake | All | Capped at 50% (about 10,000 fans) capacity from start of season. |
| San Jose Earthquakes | All | Capped at 20% (about 3,600 fans) capacity from start of season. |
| Seattle Sounders FC | All | Capped at 25% (about 15,000 fans) capacity from start of season. |
| Sporting Kansas City | All | Capped at 35% (about 6,500 fans) capacity from start of season. Opened to 100% capacity beginning May 29. |
| Toronto FC | Some | Home matches played at Exploria Stadium in Orlando before July were played with no audience. Home matches played at BMO Field were capped at 7,000 fans on July 17 followed by 15,000 fans since July 21. |
| Vancouver Whitecaps FC | Some | Have returned to BC Place |

## Attendance
### Average home attendances

    As of November 7, 2021
Games without fans are not counted in averages or games played. Additionally, multiple games (above all the NYCFC games at Yankee Stadium) did not have their attendance listed and are also not counted in averages or games played.
| Rank | Team | GP | Cumulative | High | Low | Mean |
| 1 | Atlanta United FC | 17 | 747,386 | 67,507 | 20,335 | 43,964 |
| 2 | Seattle Sounders FC | 17 | 427,121 | 45,737 | 7,042 | 25,125 |
| 3 | Portland Timbers | 12 | 255,412 | 25,218 | 16,086 | 21,284 |
| 4 | FC Cincinnati | 17 | 359,969 | 25,701 | 6,000 | 21,175 |
| 5 | Austin FC | 15 | 310,832 | 20,738 | 20,500 | 20,722 |
| 6 | Nashville SC | 16 | 309,405 | 26,913 | 12,164 | 19,338 |
| 7 | Sporting Kansas City | 15 | 282,608 | 20,213 | 16,888 | 18,841 |
| 8 | Los Angeles FC | 17 | 318,800 | 22,510 | 4,900 | 18,753 |
| 9 | New England Revolution | 12 | 215,381 | 31,635 | 7,905 | 17,948 |
| 10 | Columbus Crew | 17 | 281,918 | 20,407 | 5,180 | 16,583 |
| 11 | LA Galaxy | 17 | 266,493 | 25,174 | 6,853 | 15,676 |
| 12 | Orlando City SC | 16 | 250,299 | 19,009 | 11,503 | 15,644 |
| 13 | Real Salt Lake | 17 | 261,677 | 20,738 | 9,842 | 15,393 |
| 14 | Minnesota United FC | 13 | 192,193 | 19,691 | 4,100 | 14,784 |
| 15 | Inter Miami CF | 17 | 235,403 | 17,926 | 7,939 | 13,847 |
| 16 | FC Dallas | 17 | 228,110 | 19,096 | 8,621 | 13,418 |
| 17 | New York Red Bulls | 13 | 170,563 | 18,613 | 9,193 | 13,120 |
| 18 | Philadelphia Union | 15 | 193,552 | 18,575 | 5,000 | 12,903 |
| 19 | D.C. United | 17 | 217,441 | 18,034 | 3,935 | 12,791 |
| 20 | San Jose Earthquakes | 13 | 160,239 | 18,000 | 5,000 | 12,326 |
| 21 | Houston Dynamo FC | 17 | 207,732 | 20,021 | 6,376 | 12,220 |
| 22 | Vancouver Whitecaps FC | 7 | 84,560 | 25,117 | 7,503 | 12,080 |
| 23 | CF Montréal | 1 | 11,000 | 11,000 | 11,000 | 11,000 |
| 24 | Colorado Rapids | 12 | 144,169 | 17,104 | 8,321 | 10,792 |
| 25 | Chicago Fire FC | 17 | 181,949 | 31,308 | 5,593 | 10,703 |
| 26 | Toronto FC | 9 | 71,080 | 11,166 | 5,026 | 7,898 |
| 27 | New York City FC | 7 | 41,556 | 13,503 | 2,873 | 5,937 |
| Total | Total | 180 | 2,762,942 | 67,507 | 0 | 15,350 |

### Highest attendances

Regular season
| Rank | Home team | Score | Away team | Attendance | Date | Week | Stadium |
| 1 | Atlanta United FC | 0–1 | Columbus Crew | 67,507 | July 24, 2021 | 13 | Mercedes-Benz Stadium |
| 2 | Atlanta United FC | 1–0 | New York Red Bulls | 67,503 | August 15, 2021 | 19 | Mercedes-Benz Stadium |
| 3 | Seattle Sounders FC | 1–3 | Portland Timbers | 45,737 | August 29, 2021 | 22 | Lumen Field |
| 4 | Atlanta United FC | 0–0 | New York Red Bulls | 42,575 | June 27, 2021 | 9 | Mercedes-Benz Stadium |
| 5 | Atlanta United FC | 2–2 | Philadelphia Union | 42,523 | June 20, 2021 | 8 | Mercedes-Benz Stadium |
| 6 | Atlanta United FC | 0–1 | New England Revolution | 42,517 | July 17, 2021 | 12 | Mercedes-Benz Stadium |
| 7 | Atlanta United FC | 2–2 | Nashville SC | 40,748 | May 29, 2021 | 7 | Mercedes-Benz Stadium |
| 8 | Atlanta United FC | 1–0 | CF Montréal | 40,116 | May 15, 2021 | 5 | Mercedes-Benz Stadium |
| 9 | Seattle Sounders FC | 1–3 | Sporting Kansas City | 32,790 | July 25, 2021 | 13 | Lumen Field |
| 10 | Seattle Sounders FC | 0–1 | San Jose Earthquakes | 32,704 | July 31, 2021 | 14 | Lumen Field |

## Player movement

The 2020 MLS Expansion Draft was held on December 15, 2020, at 10:00 am (EST).

## Player statistics
### Goals

| Rank | Player | Club | Goals |
| 1 | Valentín Castellanos | New York City FC | 19 |
| 1 | Ola Kamara | D.C. United | 19 |
| 3 | Javier Hernández | LA Galaxy | 17 |
| 3 | Raúl Ruidíaz | Seattle Sounders FC | 17 |
| 5 | Adam Buksa | New England Revolution | 16 |
| 5 | Damir Kreilach | Real Salt Lake | 16 |
| 5 | Hany Mukhtar | Nashville SC | 16 |
| 5 | Dániel Sallói | Sporting Kansas City | 16 |
| 9 | Gustavo Bou | New England Revolution | 15 |
| 9 | Johnny Russell | Sporting Kansas City | 15 |

### Hat-tricks

| Player | For | Against | Score | Date |
| Javier Hernández | LA Galaxy | New York Red Bulls | 3−2 | April 25 |
| Hany Mukhtar | Nashville SC | Chicago Fire FC | 5–1 | July 17 |
| Ricardo Pepi | FC Dallas | LA Galaxy | 4–0 | July 24 |
| Ola Kamara | D.C. United | Chicago Fire FC | 3–0 | September 15 |
| Javier Eduardo López | San Jose Earthquakes | Real Salt Lake | 3–4 | September 15 |
| Brian White | Vancouver Whitecaps FC | San Jose Earthquakes | 3–0 | October 2 |
| Cristian Arango | Los Angeles FC | FC Dallas | 3−2 | October 20 |

### Assists

| Rank | Player | Club | Assists |
| 1 | Carles Gil | New England Revolution | 18 |
| 2 | Djordje Mihailovic | CF Montréal | 16 |
| 3 | Julian Gressel | D.C. United | 13 |
| 4 | Hany Mukhtar | Nashville SC | 12 |
| 4 | Jack Price | Colorado Rapids | 12 |
| 6 | Aaron Herrera | Real Salt Lake | 11 |
| 6 | João Paulo | Seattle Sounders FC | 11 |
| 6 | Maximiliano Moralez | New York City FC | 11 |
| 6 | Albert Rusnák | Real Salt Lake | 11 |
| 10 | Luciano Acosta | FC Cincinnati | 10 |
| 10 | Mauricio Pereyra | Orlando City SC | 10 |
| 10 | Emanuel Reynoso | Minnesota United FC | 10 |
| 10 | Yeferson Soteldo | Toronto FC | 10 |

### Clean sheets

| Rank | Player | Club | Clean sheets |
| 1 | Carlos Coronel | New York Red Bulls | 13 |
| 1 | Joe Willis | Nashville SC | 13 |
| 1 | William Yarbrough | Colorado Rapids | 13 |
| 4 | Andre Blake | Philadelphia Union | 12 |
| 5 | Brad Guzan | Atlanta United FC | 11 |
| 5 | Tyler Miller | Minnesota United FC | 11 |
| 7 | Sean Johnson | New York City FC | 9 |
| 8 | Bill Hamid | D.C. United | 8 |
| 9 | Steve Clark | Portland Timbers | 7 |
| 9 | Pedro Gallese | Orlando City SC | 7 |
| 9 | Eloy Room | Columbus Crew | 7 |

## Awards
### Individual awards

| Award | Player | Club |
| Most Valuable Player | Carles Gil | New England Revolution |
| Defender of the Year | Walker Zimmerman | Nashville SC |
| Goalkeeper of the Year | Matt Turner | New England Revolution |
| Coach of the Year | Bruce Arena | New England Revolution |
| Young Player of the Year | Ricardo Pepi | FC Dallas |
| Newcomer of the Year | Cristian Arango | Los Angeles FC |
| Comeback Player of the Year | Carles Gil | New England Revolution |
| Golden Boot | Valentín Castellanos | New York City FC |
| Fair Play Award | Dave Romney | Nashville SC |
| Humanitarian of the Year | Justin Morrow | Toronto FC |
| Goal of the Year | Rubio Rubin | Real Salt Lake |
| Save of the Year | Stefan Frei | Seattle Sounders FC |

### Player / Team of the Week

* Bold denotes League Player of the Week.
Team of the Week :
| Week | Goalkeeper | Defenders | Midfielders | Forwards | Bench | Coach |
| 1 | Tytoń (CIN) | Brault-Guillard (MTL) Robinson (ATL) García (HOU) Gutiérrez (VAN) | Leal (NSH) Canouse (DCU) Rodríguez (HOU) | Berić (CHI) Hernández (LA) Ruidíaz (SEA) | Maurer (DAL) Hines-Ike (DCU) Mihailovic (MTL) Atencio (SEA) Acosta (CIN) Baird (LAFC) Sallói (SKC) | Wilfried Nancy (MTL) |
| 2 | Johnson (NYC) | Braut-Guillard (MTL) Figal (MIA) Smith (SEA) | Medina (NYC) Barco (ATL) F. Higuaín (MIA) Julio (RSL) | Cowell (SJ) Hernández (LA) Domínguez (ATX) | Ochoa (RSL) Þórarinsson (NYC) Atuesta (LAFC) Polster (NE) Asprilla (POR) Busio (SKC) Nani (ORL) | Josh Wolff (ATX) |
| 3 | Willis (NSH) | Smith (SEA) Shawcross (MIA) Sands (NYC) Tinnerholm (NYC) | Yueill (SJ) Ring (ATX) Gil (NE) | Rubin (RSL) Ruidíaz (SEA) Cowell (SJ) | Yarbrough (COL) Hollingshead (DAL) Farrell (NE) Ricuarte (DAL) Clark (RBNY) Nani (ORL) Rubio (COL) | Freddy Juarez (RSL) |
| 4 | Crépeau (VAN) | Glesnes (PHI) Zimmerman (NSH) Wilson (COL) | Muyl (NSH) Zelarayán (CLB) Bassett (COL) Dájome (VAN) | Russell (SKC) Hernández (LA) Wondolowski (SJ) | Stuver (ATX) Chanot (NYC) Clark (RBNY) dos Santos (LA) Morgan (MIA) Nani (ORL) Ruidíaz (SEA) | Greg Vanney (LA) |
| 5 | Ketterer (POR) | A. Roldan (SEA) Carlos (ORL) Arreaga (SEA) Araujo (LA) | Lod (MIN) C. Roldan (SEA) Williamson (POR) Barrios (COL) | Pulido (SKC) G. Higuaín (MIA) | Miller (MIN) Shaffelburg (TOR) Medina (NYC) Monteiro (PHI) Gil (NE) Moreno (ATL) Johnsen (MTL) | Brian Schmetzer (SEA) |
| 6 | Blake (PHI) | Van Rankin (POR) Carlos (ORL) Cameron (CIN) Hollingshead (DAL) | Rossi (LAFC) Rodríguez (HOU) Zelarayán (CLB) | Mora (POR) Bou (NE) Pulido (SKC) | Gallese (ORL) Nouhou (SEA) Glesnes (PHI) Pineda (CHI) Leal (NSH) Traustason (NE) Martínez (ATL) | Jaap Stam (CIN) |
| 7 | Bond (LA) | Rosenberry (COL) Elliott (PHI) Santos (CLB) | Gil (NE) Busio (SKC) Cásseres Jr. (RBNY) Mukhtar (NSH) | Medina (NYC) Przybyłko (PHI) Arriola (DC) | Diop (MTL) Besler (ATX) Herrera (RSL) Bassett (COL) Tajouri Shradi (NYC) Toye (MTL) Kamara (DC) | Ronny Deila (NYC) |
| 8 | Turner (NE) | Najar (DC) Gómez Andrade (SEA) Glesnes (PHI) Duncan (RBNY) | Fragapane (MIN) D. Chará (POR) Kreilach (RSL) Gil (NE) | Akindele (ORL) Zardes (CLB) | Stuver (ATX) Hollingshead (DAL) Santos (CLB) Lennon (ATL) Pozuelo (TOR) Moralez (NYC) Urruti (HOU) | Bruce Arena (NE) |
| 9 | Diop (MTL) | Métanire (MIN) Elliott (PHI) Jones (NE) | Sallói (SKC) C. Roldan (SEA) Gil (NE) Haakenson (NSH) Fragapane (MIN) | Vela (LAFC) Nani (ORL) | Shuttleworth (CHI) Maher (NSH) Acosta (CIN) Álvarez (LA) Tajouri Shradi (NYC) Ebobisse (POR) Dike (ORL) | Peter Vermes (SKC) |
| 10 | Marić (HOU) | Araujo (LA) Struna (MTL) Þórarinsson (NYC) | Nani (ORL) Acosta (CIN) Busio (SKC) Medrán (CHI) Sallói (SKC) | Hernández (LA) Pepi (DAL) | Stuver (ATX) Fontàs (SKC) Paulo (SEA) Rusnák (RSL) Dájome (VAN) Andrade (NYC) Hunou (MIN) | Luchi Gonzalez (DAL) |
| 11 | Melia (SKC) | Najar (DC) Segura (LAFC) Paredes (DC) | Buchanan (NE) Medrán (CHI) Ring (ATX) Leal (NSH) Aliseda (CHI) | Domínguez (ATX) Klimala (RBNY) | Coronel (RBNY) Cameron (CIN) A. Roldan (SEA) Davis (RBNY) Choinière (MTL) Zardes (CLB) Pepi (DAL) | Gerhard Struber (RBNY) |
| 12 | Romero (LAFC) | Mbaizo (PHI) Raveloson (LA) Tolkin (RBNY) | Kreilach (RSL) K. Acosta (COL) Paulo (SEA) Medrán (CHI) Mihailovic (MTL) | Soteldo (TOR) Zelarayán (CLB) | Shuttleworth (CHI) Segura (LAFC) Mukhtar (NSH) Rowe (SEA) Lletget (LA) L. Acosta (CIN) Conway (ATL) | Javier Pérez (TOR) |
| 13 | Ochoa (RSL) | Moon-hwan (LAFC) Elliott (PHI) Morrow (TOR) | Bassett (COL) Nagbe (CLB) Mukhtar (NSH) Hamdi (MTL) | Brenner (CIN) Toye (MTL) Vela (LAFC) | Room (CLB) Lovitz (NSH) Gil (NE) Lod (MIN) Ebobisse (POR) Dájome (VAN) Santos (PHI) | Adrian Heath (MIN) |
| 14 | Vermeer (CIN) | Atencio (SEA) Abubakar (COL) Hernández (ATL) | Tajouri-Shradi (NYC) D. Chará (POR) Perea (ORL) Traustason (NE) | Mora (POR) Buksa (NE) Ruidíaz (SEA) | Willis (NSH) Nathan (SJ) Paredes (DC) Priso (TOR) Raveloson (LA) Gil (NE) Sallói (SKC) | Brian Schmetzer (SEA) |
| 15 | Bono (TOR) | Amundsen (NYC) Mensah (CLB) Che (DAL) | Moralez (NYC) Walter (SKC) Reynoso (MIN) Gressel (DC) | Bou (NE) Sapong (NSH) Pepi (DAL) | Room (CLB) Glad (RSL) Gasper (MIN) Cifuentes (LAFC) Soteldo (TOR) Przybyłko (PHI) Castellanos (NYC) | Kerry Zavagnin (SKC) |
| 16 | Marcinkowski (SJ) | Wagner (PHI) R. Castellanos (NSH) Araujo (LA) | Nani (ORL) Gil (NE) Reynoso (MIN) Pomykal (DAL) | Dájome (VAN) G. Higuaín (MIA) Andrade (NYC) | Hamid (DC) Tafari (DAL) Raveloson (LA) Parks (NYC) van der Water (ORL) Barrios (COL) Buksa (NE) | Luchi Gonzalez (DAL) |
| 17 | Slonina (CHI) | Gibbs (MIA) Farrell (NE) Zusi (SKC) | Álvarez (LA) Pochettino (ATX) Gazdag (PHI) Moreno (ATL) | Sallói (SKC) Santos (PHI) Reyna (DC) | Maurer (DAL) Glesnes (PHI) Paulo (SEA) Nani (ORL) Jara (DAL) Mora (POR) Kamara (DC) | Hernán Losada (DC) |
| 18 | Ivačič (POR) | Jones (NE) Nathan (SJ) Najar (DC) | Barco (ATL) Pozuelo (TOR) Matuidi (MIA) Stojanović (CHI) | Schön (DAL) Asprilla (POR) Espinoza (SJ) | Turner (NE) Kallman (MIN) Hollingshead (DAL) Reynoso (MIN) Kaye (COL) Castellanos (NYC) Nani (ORL) | Rob Valentino (ATL) |
| 19 | Klinsmann (LA) | Calvo (CHI) Fontàs (SKC) Sands (NYC) | Bassett (COL) Barco (ATL) Wanyama (MTL) Buchanan (NE) | Castellanos (NYC) Sapong (NSH) Ruidíaz (SEA) | Yarbrough (COL) Fall (LAFC) Stojanović (CHI) Rusnák (RSL) Muyl (NSH) Montero (SEA) Pulido (SKC) | Brian Schmetzer (SEA) |
| 20 | Coronel (RBNY) | Wagner (PHI) Zimmerman (NSH) Galván (COL) | Sallói (SKC) Gauld (VAN) McNamara (NE) Barco (ATL) Julio (RSL) | G. Higuaín (MIA) Ruidíaz (SEA) | Breza (MTL) Robinson (ATL) Tolkin (RBNY) Trapp (MIN) Stojanović (CHI) Boateng (NE) Mora (POR) | Robin Fraser (COL) |
| 21 | Melia (SKC) | González Pírez (MIA) Arreaga (SEA) Carlos (ORL) | Moreno (ATL) Pizarro (MIA) Gauld (VAN) Kaye (COL) Fagúndez (ATX) | Buksa (NE) Ebobisse (SJ) | Crépeau (VAN) Tafari (DAL) Abecasis (SJ) Paulo (SEA) Sullivan (PHI) Buchanan (NE) Driussi (ATX) | Matías Almeyda (SJ) |
| 22 | Clark (POR) | Lovitz (NSH) Sánchez (SKC) Terán (CHI) | Rodríguez (LAFC) Ferreira (DAL) Zelarayán (CLB) Gauld (VAN) | Hunou (MIN) Castellanos (NYC) Pepi (DAL) | Marsman (MIA) Mihailovic (MTL) Moralez (NYC) Reyna (DC) Joveljić (LA) Berry (CLB) Mora (POR) | Giovanni Savarese (POR) |
| 23 | Knighton (NE) | Fall (LAFC) Godoy (VAN) Figal (MIA) | Menéndez (RSL) Atuesta (LAFC) Mukhtar (NSH) Polster (NE) Barrios (COL) | Dike (ORL) Mora (POR) | Clark (POR) Lovitz (NSH) Urso (ORL) Gauld (VAN) Rusnák (RSL) Ferreira (DAL) Badji (COL) | Bob Bradley (LAFC) |
| 24 | Marsman (MIA) | Zimmerman (NSH) Steres (LA) Che (DAL) | Acosta (CIN) Paulo (SEA) Gil (NE) Blanco (POR) | Picault (HOU) Arango (LAFC) Barco (ATL) | Frei (SEA) Campbell (ATL) Gregore (MIA) Mauri (SKC) Buchanan (NE) Barrios (COL) Pepi (DAL) | Gonzalo Pineda (ATL) |
| 25 | Nelson (HOU) | Makoun (MIA) Franco (ATL) Mensah (CLB) | Russell (SKC) López (SJ) Rusnák (RSL) Obrian (DAL) | Kamara (DC) Martínez (ATL) Quioto (MTL) | Hamid (DC) Cifuentes (LAFC) Blanco (POR) Mihailovic (MTL) Medina (NYC) Barco (ATL) Rubin (RSL) | Peter Vermes (SKC) |
| 26 | Room (CLB) | Bello (ATL) Mabiala (POR) Auro (TOR) | Fernandez (RBNY) Reynoso (MIN) López (SJ) Barco (ATL) | Przybyłko (PHI) Fábio (RBNY) Kreilach (RSL) | Pantemis (MTL) Herrera (RSL) Parks (NYC) Price (COL) Mihailovic (MTL) Obrian (DAL) Dorsey (HOU) | Jim Curtin (PHI) |
| 27 | Crépeau (VAN) | Bravo (POR) Glesnes (PHI) Duncan (RBNY) | Y. Chará (POR) Mukhtar (NSH) Paulo (SEA) López (SJ) Gressel (DC) | Zardes (CLB) Buksa (NE) | Coronel (RBNY) Birnbaum (DC) Martínez (PHI) D. Chará (POR) Fragapane (MIN) Arriola (DC) Djitté (ATX) | Bruce Arena (NE) |
| 28 | Ochoa (RSL) | Trusty (COL) Robinson (ATL) Najar (DC) | Shaffelburg (TOR) Roldan (SEA) F. Navarro (CHI) Asprilla (POR) | Bou (NE) Ruidíaz (SEA) Sallói (SKC) | Crépeau (VAN) Gómez Andrade (SEA) Hadebe (HOU) José Martínez (PHI) Price (COL) Kreilach (RSL) Josef Martínez (ATL) | Hernán Losada (DC) |
| 29 | Blake (PHI) | Gutman (RBNY) Fall (LAFC) Zimmerman (NSH) | Domínguez (ATX) C. Roldan (SEA) Paulo (SEA) Russell (SKC) | Quioto (MTL) White (VAN) Soteldo (TOR) | Phelipe (DAL) Callens (NYC) Kinda (SKC) Bedoya (PHI) Sallói (SKC) Dike (ORL) Niezgoda (POR) | Wilfried Nancy (MTL) |
| 30 | Miller (MIN) | Gutman (RBNY) Pines (DC) Herrera (RSL) | Santos (CLB) Urso (ORL) Moreno (ATL) Quintero (HOU) | Arango (LAFC) Kreilach (RSL) Zardes (CLB) | Willis (NSH) Paredes (DC) Araujo (LA) Medrán (CHI) Cásseres Jr. (RBNY) Kljestan (LA) White (VAN) | Pablo Mastroeni (RSL) |
| 31 | Bond (LA) | Makoun (MIA) Camacho (MTL) Nathan (SJ) | Chú (SEA) Reynoso (MIN) Mukhtar (NSH) Caicedo (VAN) | Arango (LAFC) Buksa (NE) Berić (CHI) | Turner (NE) Wilson (COL) Moreno (ATL) Fragapane (MIN) Kikanovic (SJ) Gazdag (PHI) Cabral (LA) | Vanni Sartini (VAN) |
| 32 | Slonina (CHI) | Galván (COL) Nealis (RBNY) Elliot (PHI) Gaspar (VAN) | Alonso (MIN) Walter (SKC) Ring (ATX) | G. Higuaín (MIA) Buksa (NE) Castellanos (NYC) | Pantemis (MTL) Amundsen (NYC) Trusty (COL) Osorio (TOR) Lletget (LA) F. Higuaín (MIA) Jara (DAL) | Ronny Deila (NYC) |
| 33 | Hamid (DC) | Wagner (PHI) Kessler (NE) Moon-hwan (LAFC) | Leal (NSH) Zelarayán (CLB) Blessing (LAFC) Meram (RSL) | Araújo (ATL) Asprilla (POR) Russell (SKC) | Blackman (LAFC) Birnbaum (DC) Parks (NYC) Gil (NE) Barco (ATL) White (VAN) Sapong (NSH) | Bruce Arena (NE) |
| 34 | Johnson (NYC) | DePuy (LA) Carlos (ORL) Nealis (RBNY) | Fragapane (MIN) Ferreira (DAL) Zelarayán (CLB) Gazdag (PHI) Cowell (SJ) | Castellanos (NYC) Hernández (LA) | Frei (SEA) Dibassy (MIN) Reynoso (MIN) Parks (NYC) Rusnák (RSL) Mukhtar (NSH) Badji (COL) | Adrian Heath (MIN) |
| 35 | Crépeau (VAN) | Brody (RSL) Robinson (ATL) Moreira (CLB) | Acosta (COL) Blanco (POR) Gauld (VAN) Gressel (DC) | Kreilach (RSL) Hernández (LA) Lewis (COL) | Gallese (ORL) González Pírez (MIA) Lod (MIN) Stroud (ATX) Dike (ORL) Castellanos (NYC) Kamara (DC) | Robin Fraser (COL) |

### Goal of the Week

Goal of the Week :
| Week | Player | Club |
| 1 | João Paulo | Seattle Sounders FC |
| 2 | Esequiel Barco | Atlanta United FC |
| 3 | Nani | Orlando City SC |
| 4 | Rubio Rubin | Real Salt Lake |
| 5 | Cristian Roldan | Seattle Sounders FC |
| 6 | Lucas Zelarayán | Columbus Crew |
| 7 | Gianluca Busio | Sporting Kansas City |
| 8 | Jakob Glesnes | Philadelphia Union |
| 9 | Efraín Álvarez | LA Galaxy |
| 10 | Quinn Sullivan | Philadelphia Union |
| 11 | Cristian Cásseres Jr. | New York Red Bulls |
| 12 | Lucas Zelarayán | Columbus Crew |
| 13 | Carlos Vela | Los Angeles FC |
| 14 | Raúl Ruidíaz | Seattle Sounders FC |
| 15 | Gustavo Bou | New England Revolution |
| 16 | Rayan Raveloson | LA Galaxy |
| 17 | Yordy Reyna | D.C. United |
| 18 | Paxten Aaronson | Philadelphia Union |
| 19 | Jimmy Medranda | Seattle Sounders FC |
| 20 | Raúl Ruidíaz | Seattle Sounders FC |
| 21 | Quinn Sullivan | Philadelphia Union |
| 22 | Brian Rodríguez | Los Angeles FC |
| 23 | Daryl Dike | Orlando City SC |
| 24 | Esequiel Barco | Atlanta United FC |
| 25 | Luiz Araújo | Atlanta United FC |
| 26 | Esequiel Barco | Atlanta United FC |
| 27 | McKinze Gaines | Austin FC |
| 28 | Anderson Julio | Real Salt Lake |
| 29 | João Paulo | Seattle Sounders FC |
| 30 | Darwin Quintero | Houston Dynamo FC |
| 31 | Luka Stojanović | Chicago Fire FC |
| 32 | Sebastian Lletget | LA Galaxy |
| 33 | Dairon Asprilla | Portland Timbers |
| 34 | Lucas Zelarayán | Columbus Crew |
| 35 | Josef Martínez | Atlanta United FC |

### Player of the Month

| Month | Player | Club | Stats |
| April/May | Javier Hernández | LA Galaxy | 7G, 1A |
| June | Carles Gil | New England Revolution | 5A |
| July | Gustavo Bou | New England Revolution | 5G, 1A |
| August | Valentín Castellanos | New York City FC | 5G, 2A |
| September | Javier Eduardo López | San Jose Earthquakes | 6G, 1A |
| October/November | Valentín Castellanos | New York City FC | 6G, 1A |

### Best XI

| Goalkeeper | Defenders | Midfielders | Forwards | Ref |
| Matt Turner (NE) | Walker Zimmerman (NSH) Yeimar Gómez (SEA) Miles Robinson (ATL) | Tajon Buchanan (NE) Carles Gil (NE) Hany Mukhtar (NSH) João Paulo (SEA) | Gustavo Bou (NE) Valentín Castellanos (NYC) Raúl Ruidíaz (SEA) | |