OpenLLM-France/wikimedia huggingface dataset:
# FIND Technology

FIND® technology is a directed evolution technology that uses DNA recombination to improve properties of proteins. It eliminates unimportant and deleterious mutations while maintaining and combining beneficial mutations that would enhance protein function.

## Procedures

For the relevant gene, a library of single stranded oligonucleotides is acquired and then mutated using random mutagenesis. The newly mutated library is then subjected to exonuclease activity, creating both sense and anti-sense fragments. The areas of partially overlapping fragments are then combined and extended using a PCR-like method. These double stranded mutants are then screened for the desired optimized function using a relevant assay. The best mutants are chosen for further exonuclease activity. The process (exonuclease, PCR-like recombination, and mutant screening) is repeated, usually about 10-12 times, in order to achieve the best possible mutants with only beneficial mutations.

## Example
### CHIPS

CHIPS is a protein that inhibits immune cell activation normally associated with inflammation. CHIPS has potential as an anti-inflammatory agent, but native CHIP has been associated with activation and interaction with antibodies. FIND® technology was used to create a truncated, yet functional mutant of this protein with reduced antibody interaction.

## Intellectual property

The company Alligator Bioscience has the intellectual rights to the FIND technology and uses it both for contract work optimizing proteins for the pharmaceutical industry and to develop their own protein drugs.
# Dadade

Dadade is a village in the Palghar district of Maharashtra, India. It is located in the Vikramgad taluka.

## Demographics

According to the 2011 census of India, Dadade has 851 households. The effective literacy rate (i.e. the literacy rate of population excluding children aged 6 and below) is 61.69%.
Demographics (2011 Census) :
| | Total | Male | Female |
| Population | 5251 | 2622 | 2629 |
| Children aged below 6 years | 866 | 419 | 447 |
| Scheduled caste | 2 | 1 | 1 |
| Scheduled tribe | 5189 | 2588 | 2601 |
| Literates | 2705 | 1554 | 1151 |
| Workers (all) | 2407 | 1243 | 1164 |
| Main workers (total) | 2288 | 1149 | 1139 |
| Main workers: Cultivators | 1583 | 780 | 803 |
| Main workers: Agricultural labourers | 626 | 308 | 318 |
| Main workers: Household industry workers | 5 | 1 | 4 |
| Main workers: Other | 74 | 60 | 14 |
| Marginal workers (total) | 119 | 94 | 25 |
| Marginal workers: Cultivators | 16 | 7 | 9 |
| Marginal workers: Agricultural labourers | 97 | 84 | 13 |
| Marginal workers: Household industry workers | 1 | 1 | 0 |
| Marginal workers: Others | 5 | 2 | 3 |
| Non-workers | 2844 | 1379 | 1465 |
# Octadecadienoic acid

Octadecadienoic acid may refer to:
* Conjugated linoleic acids
* Linoleic acid, (9Z,12Z)-9,12-octadecadienoic acid
* Linolelaidic acid, (9E,12E)-9,12-octadecadienoic acid
* Rumenic acid, (9Z,11E)-9,11-octadecadienoic acid
# Betty Madigan

Betty Madigan (born 1928) is an American former traditional popular singer and actress.
Born in Washington, D.C., Madigan attended Catholic University.

## Career

In 1954, Madigan was rated "the newer female vocalist [with] the greatest chance to become one of the top female vocalist names" in a poll of disc jockeys conducted by Billboard. That year, she appeared on The Red Skelton Hour, The Dave Garroway Show, and The Colgate Comedy Hour. In 1956, she portrayed Martha Cratchitt in a 1956 episode of The Alcoa Hour called "The Stingiest Man in Town," a musical adaptation of Charles Dickens' A Christmas Carol. Madigan performed on The Ed Sullivan Show in 1957, and on The Dick Clark Show on 1958.
A description of Madigan in a 1959 issue of Gramophone said that she sounds like Alma Cogan and also resembles her.
In November 2018, Jasmine Records released a two-CD compilation of her singles recorded between 1953 and 1961, totaling 58 songs,. Sepia Records also released a CD containing two of her albums, "Am I Blue?" and "The Jerome Kern Songbook"

## Personal life

Madigan lives in Bal Harbour, Florida, where she is socially active.

## Hit records

* "Joey" (1954) (peak position on Cash Box No. 22) (released by MGM Records as catalog number 11716, with the flip side "And So I Walked Home")
* "Always You" (1954) (released by MGM Records as catalog number 11812, with the flip side "That Was My Heart You Broke")
* "Dance, Everyone, Dance" (1958) – US Billboard Hot 100 No. 31 (released by Coral Records as catalog number 62007, with the flip side "My Symphony of Love")
# Bernice Wood

C. Bernice Wood (October 12, 1895 – July 1, 1933) was an American Negro league pitcher in the 1910s.
A native of Macon, Missouri, Wood played for the Chicago American Giants in 1916. He died in Riverside, California in 1933 at age 37.
# Bethlehem Township, Ohio

Bethlehem Township, Ohio, may refer to:
* Bethlehem Township, Stark County, Ohio
* Bethlehem Township, Coshocton County, Ohio
# Ockers

Ockers is a surname. Notable people with the surname include:
* Stan Ockers (1920–1956), Belgian cyclist
* Weyn Ockers (died 1568), Dutch Protestant iconoclastic
# Better Times (album)

Better Times is the seventh studio album by Australian rock band The Black Sorrows. The album was released in September 1992 and peaked at number 13 on the ARIA Albums Chart, becoming the band's third consecutive top-twenty album.
In March 1993, the album was re-released with The Revelators' Amazing Stories. Upon re-release, the album peaked at number 14 on the ARIA Albums Chart.
At the ARIA Music Awards of 1993, the album earned The Black Sorrows a nomination for Best Group, losing to "Weather with You" by Crowded House. Joe Camilleri was nominated for Producer of the Year for his work on this album, but lost to Simon Hussey. Pascoe & Gray Design and Eryk Photography were nominated for Best Cover Art for their work on Better Times, but lost to Paul McNeil and Richard All.

## Track listing

* "Better Times" (Joe Camilleri, Laurie Polec)
* "Come On, Come On" (Joe Camilleri, Laurie Polec)
* "Ain't Love the Strangest Thing" (Joe Camilleri, Laurie Polec)
* "A Night Like This" (Joe Camilleri, Laurie Polec)
* "Too Long Gone" (Joe Camilleri, Laurie Polec)
* "Stella" (Joe Camilleri, Laurie Polec)
* "Steps of Time" (Joe Camilleri)
* "Bitter Cup"(Joe Camilleri, Laurie Polec)
* "Sweet Inspiration" (Joe Camilleri, Laurie Polec)
* "Storm Wind" (Joe Camilleri, Laurie Polec)
* "Resurrection" (Joe Camilleri, Laurie Polec)

## Charts

Chart performance for Better Times :
| Chart (1992) | Peak position |
| Australian Albums (ARIA) | 13 |
# Calycophyllum

Calycophyllum is a genus of flowering plants in the family Rubiaceae. It was described by Augustin Pyramus de Candolle in 1830. The genus is found from Mexico, Central America, South America and the West Indies.

## Species

* Calycophyllum candidissimum (Vahl) DC. common names: lemonwood, digame lancewood - Mexico (Campeche, Chiapas, Oaxaca, Veracruz), Belize, Central America, Cuba, Trinidad, Venezuela, Colombia
* Calycophyllum intonsum Steyerm. - Venezuela, Guyana, Brazil
* Calycophyllum megistocaulum (K.Krause) C.M.Taylor - Bolivia, Colombia, Ecuador, Peru, Brazil
* Calycophyllum merumense Steyerm. - Guyana
* Calycophyllum multiflorum Griseb. - Bolivia, Brazil, Argentina, Paraguay
* Calycophyllum obovatum (Ducke) Ducke - Guyana, Venezuela, Colombia, Brazil
* Calycophyllum papillosum J.H.Kirkbr. - Brazil (Espírito Santo)
* Calycophyllum spectabile Steyerm. - Guyana
* Calycophyllum spruceanum (Benth.) Hook.f. ex K.Schum. - Bolivia, Colombia, Ecuador, Peru, Brazil
* Calycophyllum tefense J.H.Kirkbr. - Brazil (Amazonas)
* Calycophyllum venezuelense Steyerm. - Venezuela, Guyana
# Offer Wadham Lighthouse

The Offer Wadham Lighthouse is an active lighthouse in Newfoundland and Labrador, Canada, was lit for the first time on October 4, 1858. It was built after many petitions were sent to the government arguing for a light on the island to help guide mariners. This arose especially after the "Spring of the Wadhams" in 1852, when more than 40 sealing vessels were crushed and abandoned in the ice near Offer Wadham Island and several crew members escaped by climbing over cliffs to find shelter.

## Keepers

The first lighthouse keeper was Thomas Hennessey and his assistant was Edward Reddy. Charles Prowse was appointed keeper in November 1862 until 1901 and his assistants were William Hennessey, William Murphy, Peter Woods, and Robert Wellon. Other lighthouse keepers on the island were:
* Thomas Hennessey 1857–1863
* Charles Prowse 1863–1899
* Elias Abbott 1899–1904
* Stephen Abbot 1905–1908
* William Pomeroy 1909–1916
* James Ford Mouland 1916–1936
* Arch Way, Walter Hicks at least 1941–at least 194)

## Description

The lighthouse is described in the Newfoundland Almanac as a steady, fixed, white 4th-order dioptric burning on a circular brick tower at an arc of 360 degrees with a 2-wick concentric lamp. It was 100 feet (30 m) above sea level and could be seen at about 15 nautical miles (28 km; 17 mi).
# Campbell Creek

Campbell Creek may refer to:

## Australia

* Campbell Creek, Queensland, a locality in the North Burnett Region, Queensland

## United States

* Campbell Creek (Alaska), a stream in Anchorage
* Campbell Creek (California), a tributary of the Trinity River
* Campbell Creek (Pine Creek tributary), a stream in Warren County, Pennsylvania
* Campbell Creek (Charles Mix County, South Dakota), a stream
* Campbell Creek (Harding County, South Dakota), a stream
* Campbell Creek, historic name for today's Saratoga Creek, in Santa Clara County, California
# Octetra

Octetra is a concrete sculpture by Isamu Noguchi (1904–1988) from 1968.

## Description

It is an abstract painted concrete sculpture. It was designed to be a play structure.

## History

It was first exhibited near Spoleto Cathedral
There are examples at Robert T. Webb Sculpture Garden, Takamatsu Japan, Moerenuma Park.
It was shown at the Pace Gallery.
# For Now, For Always

"For Now, For Always" was a sentimental ballad from the 1961 Disney film, The Parent Trap. It was sung by Maureen O'Hara, and was written by the songwriting brother team of the Robert and Richard Sherman.
According to the Sherman Brothers, the song was meant to be in the style of a 1946 love ballad, perhaps written as World War II was ending or had just ended, so that it could be the song that the twins' parents would have fallen in love to.

## Literary Sources

* Sherman, Robert B. Walt's Time: from before to beyond. Santa Clarita: Camphor Tree Publishers, 1998.
* This 1960s single-related article is a stub. You can help Wikipedia by expanding it.
* v
* t
* e
# Dayville, Connecticut

Dayville, Connecticut may refer to:
* Dayville (CDP), Connecticut, a census-designated place
* Dayville Historic District, a historic district within the CDP
# Beverly Hills Caviar Automated Boutique

The Beverly Hills Caviar Automated Boutique sells caviar, escargot and truffles from vending machines.
In 2013, the machines began operating in three locations: Westfield Century City, Westfield Topanga and Hollywood and Highland Center. The owners credit their daughter for coming up with the idea when they were purchasing a cupcake from a vending machine. The coverage of the placement of the machines included the comments "I feel sure that, very soon, you will be able to buy engagement rings, tiaras, mink coats and leather bodices amid all the excitement of the mall -- but without the interruption of some obsequious store assistant," from CNet, and a marketing analyst stating that the idea was merely to generate buzz.
The machines offer a selection of caviar in different sizes ranging from 40 grams (1.5 ounces) to 400 grams (a little less than a pound). The caviar ranges in price from $30 an ounce for American Black caviar to $500 an ounce for Imperial River Beluga caviar, as well as vegan caviar and dried mullet caviar (popular in Algerian, French, Jordanian, Spanish, and Tunisian cuisine). In addition to caviar, the machines offer blinis, escargot, flavored salts, and Italian truffles. The machine was built in Spain. The machine holds about $50,000 worth of temperature-controlled merchandise. After being dispensed, the product takes about 30 minutes to thaw but can stay cool up to 3 hours in an insulated box.
# Odd Fellows Temple

Odd Fellows Temple may refer to:

## in the United States

* Odd Fellows Temple (Pasadena, California), listed on the NRHP in California
* Odd Fellows Temple (Lexington, Kentucky), listed on the NRHP in Kentucky
* Odd Fellows Temple (Waterville, Maine), listed on the NRHP in Maine
* Odd Fellows Temple (East Liverpool, Ohio), listed on the NRHP in Ohio
# Florida Atlantic Owls basketball

The Florida Atlantic Owls have two basketball programs:
* Florida Atlantic Owls men's basketball
* Florida Atlantic Owls women's basketball
# Candy Buttons

Candy Buttons, Candy Dots, or Pox are small rounded flat pegs of candy that are attached to a strip of paper. This classic sugar candy was originally introduced by the Cumberland Valley company and J Sudak and Son of Williamsburg, Brooklyn. In 1977, Sudak, which changed its name to Uncle Nibbles Candy Factory, sold to a repackager in Manhattan named CeeDee Candy, they sold to NECCO. After that acquisition, Necco bought the Cumberland Valley Company in 1980, which made them the exclusive manufacturer of this product in the United States. Each strip of the candy includes three flavors: cherry (pink), lime (blue), and lemon (yellow). Candy Buttons come in two strip sizes: long and short. The long is 221⁄2 inches, while the short is 111⁄4 inches. NECCO made 750 million candy buttons in the course of a year. Following NECCO's 2018 bankruptcy, Candy Buttons were bought at auction by Cincinnati's Doscher's Candies. They were subsequently the first former Necco candy back to market.
Engineer and inventor George Theofiel Dib is credited with the invention of the candy button machine.
# Okehampton College

Okehampton College is a co-educational secondary school and sixth form located in Okehampton in the English county of Devon.

## History

Previously a foundation school administered by Devon County Council, in January 2018 Okehampton College converted to academy status and is now sponsored by the Dartmoor Multi-Academy Trust.

## Admissions

Pupils are normally admitted from Boasley Cross Community Primary School, Bridestowe Primary School, Chagford CE Primary School, Exbourne CE Primary School, Hatherleigh Community Primary School, Lew Trenchard CE Primary School, Lydford School, Northlew & Ashbury Parochial Primary School, North Tawton Community Primary School, Okehampton Primary School and South Tawton Primary School. The school also operates a federation with Holsworthy Community College in Holsworthy.

## Academics

Okehampton College offers GCSEs, BTECs and OCR Nationals as programmes of study for pupils, while students in the sixth form have the option to study from a range of A Levels, NVQs and further BTECs.

## Notable awards

* Zayed Future Energy Prize - 2013 winner
* 'Outstanding' OFSTED report - 2014

## Notable former pupils

* Georgina Geikie, sport shooter
* Steve Holliday, businessman
# Beverly P. Lynch

Beverly P. Lynch is an American scholar, professor, librarian, and administrator. She was president of the American Library Association from 1985 to 1986.

## Education

Lynch earned a Bachelor of Science degree with majors in English and music from North Dakota State University, a Masters of Science degree in library sciences from the University of Illinois at Urbana–Champaign, and a Ph.D. from the University of Wisconsin–Madison.

## Career

Lynch was executive director of the Association of College and Research Libraries from 1972 to 1977. She was the university librarian at the University of Illinois at Chicago from 1977 to 1989.
In 1989 she was appointed dean of the University of California Los Angeles UCLA School of Education and Information Studies. She was far-thinking about education for librarians. She also directed the UCLA Senior Fellows program from 1991 to 2017, one of the most impactful professional development programs in academic librarianship.
From 2000 to 2001 she took leave to lead the Center for Research Libraries.
Returning to UCLA she became the first director of UCLA's California Rare Book School.
She served as president of the American Library Association from 1985 to 1986. Her papers are held at the American Library Association Archives.

## Awards

In 1987, she was honored as a distinguished alumna by the University of Illinois Urbana-Champaign. She received a similar honor in 2009 from the University of Wisconsin at Madison.
Lynch won the highest honors from the American Library Association. She was awarded the Joseph W. Lippincott Award in 2009, Melvil Dewey Medal in 2012 and the Beta Phi Mu Award for distinguished service to education for librarianship education in 2015.
# De Garengeot's hernia

De Garengeot's hernia is a rare subtype of an incarcerated femoral hernia. This eponym may be used to describe the incarceration of the vermiform appendix within a femoral hernia. This mechanism is contrasted with the Amyand hernia, in which the appendix protrudes through an inguinal hernia.
Akopian and Alexander, named this hernia after the 18th century Parisian surgeon Rene Jacques Croissant de Garengeot. He is quoted in the surgical literature as the first to describe this hernia in 1731. Although the surgeon's full last name is Croissant de Garengeot, for linguistic convenience it has been suggested to abbreviate this eponym to "de Garengeot". De Garengeot's first-described patient developed tenderness and a bulge in her right upper thigh after lifting 24 lb of bread. The bulge was unable to be reduced, after which surgery was conducted and a femoral hernia was discovered. The hernia was reduced back into the peritoneal cavity and the patient made an adequate recovery in 6 weeks.
Similar as with the situation of an Amyand's hernia, the true nature of the incarcerated tissue is rarely diagnosed preoperatively. Patients present clinically similar to other incarcerated femoral herniae. Treatment consists of an appendectomy and hernia repair. Laparoscopic options are described.

## Epidemiology

De Garengeot hernia are most commonly seen in females and patients between 60 and 90 years of age.

## Diagnosis

Diagnosis of De Garengeot hernia is most commonly made at the time of surgery, but some are diagnosed pre-operatively by CT scan, ultrasound, or MRI. If De Garengeot hernia is suspected based on general clinical signs of abdominal tenderness or bulging, CT scan is recommended.

## Treatment

A individualized treatment approach is required based on the severity of the hernia and the surgeon's skill level and experience. Since the condition is rare, there have not been documented randomized control trials. De Garengeot hernias can be treated with closed reduction, laparoscopic repair, appendectomy, and open repair. Mesh placement can be considered based on severity of the hernia. The most common route of surgical management was through a groin incision, and appendectomy was performed in 98.5% of patients.

## Prevention

Prevention of De Garengeot hernia involves measures that prevent hernias generally, such as maintaining a healthy weight, avoiding tight-fitting clothes, avoiding heavy straining when using the restroom, and avoiding improper heavy lifting.
# Forgive Them For They Suck K*k

Forgive Them For They Suck K*k is the first live album by Punk rock band Fokofpolisiekar. It was recorded in 2012 during the band's performance at the Barnyard Theatre in the Cresta Mall, Johannesburg. The name of the DVD was chosen after Wynand Myburgh jokingly remarked that if a follow-up DVD was made to their 2009 documentary Forgive Them For They Know Not What They Do, it should be called Forgive Them For They Suck K*k; Myburgh elaborated by saying "We do not take ourselves too seriously in Fokofpolisiekar".
# Bhagojikoppa

Bhagojikoppa is a village in Belgaum district in the southern state of Karnataka, India.
# Formica pacifica

Formica pacifica is an ant species occupying the Pacific Coast of the United States and British Columbia, Canada. This species is a member of the Formica fusca species group. Workers are quite fast and aggressive. This species engages in wars with neighboring colonies. F. pacifica is present in both forests and human settlements. Colonies of this species can grow up to a few thousand workers.

## Reproduction

Mature colonies take nuptial flights in mid-June to late August. Fertile dealate queens sometimes do not begin the egg-laying process until after their first hibernation.

## Nesting

This species prefers to build their nests in soil under rocks or other firm objects. Nest entrances can be quiet and unnoticeable, while some are marked with the soil or excavated objects from their nest.
# Dawada

The Dawada (Duwwud, Dawwada) are an Afro-Arab ethnic group from the Fezzan region of southern Libya. They live around the Gabraoun oasis, at the town of Murzuk, where they harvest brine shrimp in the salty lakes. They dry the brine shrimp and sell them to caravans. The name Dawada means "worm-folk" in Arabic due to this practice. The appearance of the Dawada is distinctive and has been linked to a relict population. They are mostly an endogamous group who rarely marry outside of their tribe. They speak an Arabic dialect.
# Beyza Durmaz

Beyza Durmaz (born 5 August 1977) is a Turkish singer, songwriter, and composer.

## Life and career

Having completed her high school education at the Private Culture High School, Durmaz took various courses in singing, guitar, piano and Turkish Art Music, at the same period while she was studying at the Faculty of Business Administration of Istanbul University, and then joined the group "Nefes" as a soloist. After graduating from university, she began to perform as Mustafa Sandal's back vocalist.
She was first featured on Burak Demir's album Dreamin' İstanbul as a guest vocalist. Durmaz's first album Koku was released in 2005. It was produced by Volkan Gucer and composed by Burak Demir. The songs on this album were written by Durmaz herself. She also sang the song for the main title of the series Sihirli Annem which was broadcast for 7 seasons.
She also collaborated with the Italian group Nemas Project on the album "Snow in Istanbul". Together with Ali Cem Çehreli, Durmaz also wrote and composed the song "Hüsran" for Mustafa Ceceli's album "Kalpten".
In 2015, she released a music video for the song "Olan Var Olmayan Var". The song ranked eighth on Google's list of most-searched songs in Turkey in 2015.

## Discography
### Albums

* Koku (2005)

### EPs

* Olan Var Olmayan Var (2015)

### Singles

* "Ben N'aptım" (2016)
* "Miras" (2018)
* "Wake Up" (feat. ToldorTunes) (2019)

## Awards and nominations

| Year | Award | Category | Nominee | Result | Ref. |
| 2006 | POPSAV 1. Achievement Awards | Best Female Newcomer Singer of the Year | Beyza Durmaz | Nominated | |
| 2006 | 12th Kral TV Video Music Awards | Best Female Newcomer Singer of the Year | Beyza Durmaz | Nominated | |