# List of Hot 100 Airplay number-one singles of the 2000s

This is a list of songs which received the most airplay per week on radio stations in the United States as ranked and published by Billboard magazine on the Hot 100 Airplay chart during the 2000s.

## Number-one airplay hits

| Issue date | Song | Artist(s) |
| 2000 ||||
| January 1 | "Back at One" | Brian McKnight |
| January 8 | "Back at One" | Brian McKnight |
| January 15 | "Back at One" | Brian McKnight |
| January 22 | "Back at One" | Brian McKnight |
| January 29 | "I Knew I Loved You" | Savage Garden |
| February 5 | "I Knew I Loved You" | Savage Garden |
| February 12 | "I Knew I Loved You" | Savage Garden |
| February 19 | "I Knew I Loved You" | Savage Garden |
| February 26 | "I Knew I Loved You" | Savage Garden |
| March 4 | "I Knew I Loved You" | Savage Garden |
| March 11 | "Bye Bye Bye" | 'N Sync |
| March 18 | "Bye Bye Bye" | 'N Sync |
| March 25 | "Bye Bye Bye" | 'N Sync |
| April 1 | "Bye Bye Bye" | 'N Sync |
| April 8 | "Say My Name" | Destiny's Child |
| April 15 | "Bye Bye Bye" | 'N Sync |
| April 22 | "Maria Maria" | Santana featuring The Product G&B |
| April 29 | "Thong Song" | Sisqó |
| May 6 | "Thong Song" | Sisqó |
| May 13 | "Thong Song" | Sisqó |
| May 20 | "Thong Song" | Sisqó |
| May 27 | "Thong Song" | Sisqó |
| June 3 | "Thong Song" | Sisqó |
| June 10 | "Thong Song" | Sisqó |
| June 17 | "Try Again" | Aaliyah |
| June 24 | "Try Again" | Aaliyah |
| July 1 | "Try Again" | Aaliyah |
| July 8 | "Try Again" | Aaliyah |
| July 15 | "Try Again" | Aaliyah |
| July 22 | "Try Again" | Aaliyah |
| July 29 | "Try Again" | Aaliyah |
| August 5 | "Try Again" | Aaliyah |
| August 12 | "Try Again" | Aaliyah |
| August 19 | "Jumpin' Jumpin'" | Destiny's Child |
| August 26 | "Jumpin' Jumpin'" | Destiny's Child |
| September 2 | "Jumpin' Jumpin'" | Destiny's Child |
| September 9 | "Jumpin' Jumpin'" | Destiny's Child |
| September 16 | "Jumpin' Jumpin'" | Destiny's Child |
| September 23 | "Jumpin' Jumpin'" | Destiny's Child |
| September 30 | "Jumpin' Jumpin'" | Destiny's Child |
| October 7 | "Kryptonite" | 3 Doors Down |
| October 14 | "Kryptonite" | 3 Doors Down |
| October 21 | "Kryptonite" | 3 Doors Down |
| October 28 | "Kryptonite" | 3 Doors Down |
| November 4 | "Kryptonite" | 3 Doors Down |
| November 11 | "Kryptonite" | 3 Doors Down |
| November 18 | "Independent Women Part I" | Destiny's Child |
| November 25 | "Independent Women Part I" | Destiny's Child |
| December 2 | "Independent Women Part I" | Destiny's Child |
| December 9 | "Independent Women Part I" | Destiny's Child |
| December 16 | "Independent Women Part I" | Destiny's Child |
| December 23 | "Independent Women Part I" | Destiny's Child |
| December 30 | "Independent Women Part I" | Destiny's Child |
| 2001 ||||
| January 6 | "Independent Women Part I" | Destiny's Child |
| January 13 | "Independent Women Part I" | Destiny's Child |
| January 20 | "It Wasn't Me" | Shaggy featuring Ricardo "RikRok" Ducent |
| January 27 | "It Wasn't Me" | Shaggy featuring Ricardo "RikRok" Ducent |
| February 3 | "It Wasn't Me" | Shaggy featuring Ricardo "RikRok" Ducent |
| February 10 | "It Wasn't Me" | Shaggy featuring Ricardo "RikRok" Ducent |
| February 17 | "It Wasn't Me" | Shaggy featuring Ricardo "RikRok" Ducent |
| February 24 | "Love Don't Cost a Thing" | Jennifer Lopez |
| March 3 | "Love Don't Cost a Thing" | Jennifer Lopez |
| March 10 | "Angel" | Shaggy featuring Rayvon |
| March 17 | "Angel" | Shaggy featuring Rayvon |
| March 24 | "Angel" | Shaggy featuring Rayvon |
| March 31 | "Angel" | Shaggy featuring Rayvon |
| April 7 | "Angel" | Shaggy featuring Rayvon |
| April 14 | "Survivor" | Destiny's Child |
| April 21 | "Survivor" | Destiny's Child |
| April 28 | "Survivor" | Destiny's Child |
| May 5 | "Survivor" | Destiny's Child |
| May 12 | "Survivor" | Destiny's Child |
| May 19 | "All For You" | Janet Jackson |
| May 26 | "All For You" | Janet Jackson |
| June 2 | "Lady Marmalade" | Christina Aguilera, Pink, Mýa, Lil' Kim |
| June 9 | "Lady Marmalade" | Christina Aguilera, Pink, Mýa, Lil' Kim |
| June 16 | "Lady Marmalade" | Christina Aguilera, Pink, Mýa, Lil' Kim |
| June 23 | "Lady Marmalade" | Christina Aguilera, Pink, Mýa, Lil' Kim |
| June 30 | "Lady Marmalade" | Christina Aguilera, Pink, Mýa, Lil' Kim |
| July 7 | "Lady Marmalade" | Christina Aguilera, Pink, Mýa, Lil' Kim |
| July 14 | "Hanging by a Moment" | Lifehouse |
| July 21 | "Let Me Blow Ya Mind" | Eve featuring Gwen Stefani |
| July 28 | "Let Me Blow Ya Mind" | Eve featuring Gwen Stefani |
| August 4 | "Let Me Blow Ya Mind" | Eve featuring Gwen Stefani |
| August 11 | "Let Me Blow Ya Mind" | Eve featuring Gwen Stefani |
| August 18 | "Fallin'" | Alicia Keys |
| August 25 | "Fallin'" | Alicia Keys |
| September 1 | "Fallin'" | Alicia Keys |
| September 8 | "I'm Real" | Jennifer Lopez featuring Ja Rule |
| September 15 | "I'm Real" | Jennifer Lopez featuring Ja Rule |
| September 22 | "I'm Real" | Jennifer Lopez featuring Ja Rule |
| September 29 | "Fallin" | Alicia Keys |
| October 6 | "Fallin" | Alicia Keys |
| October 13 | "Fallin" | Alicia Keys |
| October 20 | "I'm Real" | Jennifer Lopez featuring Ja Rule |
| October 27 | "I'm Real" | Jennifer Lopez featuring Ja Rule |
| November 3 | "I'm Real" | Jennifer Lopez featuring Ja Rule |
| November 10 | "Family Affair" | Mary J. Blige |
| November 17 | "Family Affair" | Mary J. Blige |
| November 24 | "Family Affair" | Mary J. Blige |
| December 1 | "Family Affair" | Mary J. Blige |
| December 8 | "Family Affair" | Mary J. Blige |
| December 15 | "U Got It Bad" | Usher |
| December 22 | "U Got It Bad" | Usher |
| December 29 | "U Got It Bad" | Usher |
| 2002 ||||
| January 5 | "U Got It Bad" | Usher |
| January 12 | "U Got It Bad" | Usher |
| January 19 | "U Got It Bad" | Usher |
| January 26 | "U Got It Bad" | Usher |
| February 2 | "U Got It Bad" | Usher |
| February 9 | "U Got It Bad" | Usher |
| February 16 | "U Got It Bad" | Usher |
| February 23 | "Always on Time" | Ja Rule featuring Ashanti |
| March 2 | "Always on Time" | Ja Rule featuring Ashanti |
| March 9 | "Ain't it Funny" | Jennifer Lopez featuring Ja Rule |
| March 16 | "Ain't it Funny" | Jennifer Lopez featuring Ja Rule |
| March 23 | "Ain't it Funny" | Jennifer Lopez featuring Ja Rule |
| March 30 | "Ain't it Funny" | Jennifer Lopez featuring Ja Rule |
| April 6 | "Ain't it Funny" | Jennifer Lopez featuring Ja Rule |
| April 13 | "Ain't it Funny" | Jennifer Lopez featuring Ja Rule |
| April 20 | "Foolish" | Ashanti |
| April 27 | "Foolish" | Ashanti |
| May 4 | "Foolish" | Ashanti |
| May 11 | "Foolish" | Ashanti |
| May 18 | "Foolish" | Ashanti |
| May 25 | "Foolish" | Ashanti |
| June 1 | "Foolish" | Ashanti |
| June 8 | "Foolish" | Ashanti |
| June 15 | "Foolish" | Ashanti |
| June 22 | "Foolish" | Ashanti |
| June 29 | "Hot in Herre" | Nelly |
| July 6 | "Hot in Herre" | Nelly |
| July 13 | "Hot in Herre" | Nelly |
| July 20 | "Hot in Herre" | Nelly |
| July 27 | "Hot in Herre" | Nelly |
| August 3 | "Hot in Herre" | Nelly |
| August 10 | "Hot in Herre" | Nelly |
| August 17 | "Dilemma" | Nelly featuring Kelly Rowland |
| August 24 | "Dilemma" | Nelly featuring Kelly Rowland |
| August 31 | "Dilemma" | Nelly featuring Kelly Rowland |
| September 7 | "Dilemma" | Nelly featuring Kelly Rowland |
| September 14 | "Dilemma" | Nelly featuring Kelly Rowland |
| September 21 | "Dilemma" | Nelly featuring Kelly Rowland |
| September 28 | "Dilemma" | Nelly featuring Kelly Rowland |
| October 5 | "Dilemma" | Nelly featuring Kelly Rowland |
| October 12 | "Dilemma" | Nelly featuring Kelly Rowland |
| October 19 | "Dilemma" | Nelly featuring Kelly Rowland |
| October 26 | "Dilemma" | Nelly featuring Kelly Rowland |
| November 2 | "Dilemma" | Nelly featuring Kelly Rowland |
| November 9 | "Lose Yourself" | Eminem |
| November 16 | "Lose Yourself" | Eminem |
| November 23 | "Lose Yourself" | Eminem |
| November 30 | "Lose Yourself" | Eminem |
| December 7 | "Lose Yourself" | Eminem |
| December 14 | "Lose Yourself" | Eminem |
| December 21 | "Lose Yourself" | Eminem |
| December 28 | "Lose Yourself" | Eminem |
| 2003 ||||
| January 4 | "Lose Yourself" | Eminem |
| January 11 | "Lose Yourself" | Eminem |
| January 18 | "Lose Yourself" | Eminem |
| January 25 | "Bump, Bump, Bump" | B2K featuring P. Diddy |
| February 1 | "Bump, Bump, Bump" | B2K featuring P. Diddy |
| February 8 | "All I Have" | Jennifer Lopez featuring LL Cool J |
| February 15 | "All I Have" | Jennifer Lopez featuring LL Cool J |
| February 22 | "All I Have" | Jennifer Lopez featuring LL Cool J |
| March 1 | "All I Have" | Jennifer Lopez featuring LL Cool J |
| March 8 | "In Da Club" | 50 Cent |
| March 15 | "In Da Club" | 50 Cent |
| March 22 | "In Da Club" | 50 Cent |
| March 29 | "In Da Club" | 50 Cent |
| April 5 | "In Da Club" | 50 Cent |
| April 12 | "In Da Club" | 50 Cent |
| April 19 | "In Da Club" | 50 Cent |
| April 26 | "In Da Club" | 50 Cent |
| May 3 | "In Da Club" | 50 Cent |
| May 10 | "Get Busy" | Sean Paul |
| May 17 | "Get Busy" | Sean Paul |
| May 24 | "Get Busy" | Sean Paul |
| May 31 | "21 Questions" | 50 Cent featuring Nate Dogg |
| June 7 | "21 Questions" | 50 Cent featuring Nate Dogg |
| June 14 | "21 Questions" | 50 Cent featuring Nate Dogg |
| June 21 | "21 Questions" | 50 Cent featuring Nate Dogg |
| June 28 | "21 Questions" | 50 Cent featuring Nate Dogg |
| July 5 | "Magic Stick" | Lil' Kim featuring 50 Cent |
| July 12 | "Crazy in Love" | Beyoncé featuring Jay-Z |
| July 19 | "Crazy in Love" | Beyoncé featuring Jay-Z |
| July 26 | "Crazy in Love" | Beyoncé featuring Jay-Z |
| August 2 | "Crazy in Love" | Beyoncé featuring Jay-Z |
| August 9 | "Crazy in Love" | Beyoncé featuring Jay-Z |
| August 16 | "Crazy in Love" | Beyoncé featuring Jay-Z |
| August 23 | "Crazy in Love" | Beyoncé featuring Jay-Z |
| August 30 | "Crazy in Love" | Beyoncé featuring Jay-Z |
| September 6 | "Shake Ya Tailfeather" | Nelly, P. Diddy and Murphy Lee |
| September 13 | "Shake Ya Tailfeather" | Nelly, P. Diddy and Murphy Lee |
| September 20 | "Shake Ya Tailfeather" | Nelly, P. Diddy and Murphy Lee |
| September 27 | "Shake Ya Tailfeather" | Nelly, P. Diddy and Murphy Lee |
| October 4 | "Baby Boy" | Beyoncé featuring Sean Paul |
| October 11 | "Baby Boy" | Beyoncé featuring Sean Paul |
| October 18 | "Baby Boy" | Beyoncé featuring Sean Paul |
| October 25 | "Baby Boy" | Beyoncé featuring Sean Paul |
| November 1 | "Baby Boy" | Beyoncé featuring Sean Paul |
| November 8 | "Baby Boy" | Beyoncé featuring Sean Paul |
| November 15 | "Baby Boy" | Beyoncé featuring Sean Paul |
| November 22 | "Baby Boy" | Beyoncé featuring Sean Paul |
| November 29 | "Baby Boy" | Beyoncé featuring Sean Paul |
| December 6 | "Stand Up" | Ludacris featuring Shawnna |
| December 13 | "Hey Ya!" | OutKast |
| December 20 | "Hey Ya!" | OutKast |
| December 27 | "Hey Ya!" | OutKast |
| 2004 ||||
| January 3 | "Hey Ya!" | OutKast |
| January 10 | "Hey Ya!" | OutKast |
| January 17 | "Hey Ya!" | OutKast |
| January 24 | "Hey Ya!" | OutKast |
| January 31 | "Hey Ya!" | OutKast |
| February 7 | "Hey Ya!" | OutKast |
| February 14 | "Slow Jamz" | Twista featuring Kanye West and Jamie Foxx |
| February 21 | "Slow Jamz" | Twista featuring Kanye West and Jamie Foxx |
| February 28 | "Yeah!" | Usher featuring Lil Jon and Ludacris |
| March 6 | "Yeah!" | Usher featuring Lil Jon and Ludacris |
| March 13 | "Yeah!" | Usher featuring Lil Jon and Ludacris |
| March 20 | "Yeah!" | Usher featuring Lil Jon and Ludacris |
| March 27 | "Yeah!" | Usher featuring Lil Jon and Ludacris |
| April 3 | "Yeah!" | Usher featuring Lil Jon and Ludacris |
| April 10 | "Yeah!" | Usher featuring Lil Jon and Ludacris |
| April 17 | "Yeah!" | Usher featuring Lil Jon and Ludacris |
| April 24 | "Yeah!" | Usher featuring Lil Jon and Ludacris |
| May 1 | "Yeah!" | Usher featuring Lil Jon and Ludacris |
| May 8 | "Yeah!" | Usher featuring Lil Jon and Ludacris |
| May 15 | "Yeah!" | Usher featuring Lil Jon and Ludacris |
| May 22 | "Burn" | Usher |
| May 29 | "Burn" | Usher |
| June 6 | "Burn" | Usher |
| June 13 | "Burn" | Usher |
| June 20 | "Burn" | Usher |
| June 27 | "Burn" | Usher |
| July 3 | "Burn" | Usher |
| July 10 | "Burn" | Usher |
| July 17 | "Confessions Part II" | Usher |
| July 24 | "Confessions Part II" | Usher |
| July 31 | "Confessions Part II" | Usher |
| August 7 | "Slow Motion" | Juvenile featuring Soulja Slim |
| August 14 | "Slow Motion" | Juvenile featuring Soulja Slim |
| August 21 | "Lean Back" | Terror Squad |
| August 28 | "Lean Back" | Terror Squad |
| September 4 | "Lean Back" | Terror Squad |
| September 11 | "Goodies" | Ciara featuring Petey Pablo |
| September 18 | "Goodies" | Ciara featuring Petey Pablo |
| September 25 | "Goodies" | Ciara featuring Petey Pablo |
| October 2 | "Goodies" | Ciara featuring Petey Pablo |
| October 9 | "Goodies" | Ciara featuring Petey Pablo |
| October 16 | "Goodies" | Ciara featuring Petey Pablo |
| October 23 | "Goodies" | Ciara featuring Petey Pablo |
| October 30 | "My Boo" | Usher and Alicia Keys |
| November 6 | "My Boo" | Usher and Alicia Keys |
| November 13 | "My Boo" | Usher and Alicia Keys |
| November 20 | "My Boo" | Usher and Alicia Keys |
| November 27 | "My Boo" | Usher and Alicia Keys |
| December 4 | "My Boo" | Usher and Alicia Keys |
| December 11 | "Drop It Like It's Hot" | Snoop Dogg featuring Pharrell |
| December 18 | "Drop It Like It's Hot" | Snoop Dogg featuring Pharrell |
| December 25 | "Drop It Like It's Hot" | Snoop Dogg featuring Pharrell |
| 2005 ||||
| January 1 | "Let Me Love You" | Mario |
| January 8 | "Let Me Love You" | Mario |
| January 15 | "Let Me Love You" | Mario |
| January 22 | "Let Me Love You" | Mario |
| January 29 | "Let Me Love You" | Mario |
| February 5 | "Let Me Love You" | Mario |
| February 12 | "Let Me Love You" | Mario |
| February 19 | "Let Me Love You" | Mario |
| February 26 | "Let Me Love You" | Mario |
| March 5 | "Let Me Love You" | Mario |
| March 12 | "Let Me Love You" | Mario |
| March 19 | "Candy Shop" | 50 Cent featuring Olivia |
| March 26 | "Candy Shop" | 50 Cent featuring Olivia |
| April 2 | "Candy Shop" | 50 Cent featuring Olivia |
| April 9 | "Candy Shop" | 50 Cent featuring Olivia |
| April 16 | "Candy Shop" | 50 Cent featuring Olivia |
| April 23 | "Candy Shop" | 50 Cent featuring Olivia |
| April 30 | "Candy Shop" | 50 Cent featuring Olivia |
| May 7 | "Hate It or Love It" | The Game featuring 50 Cent |
| May 14 | "Oh" | Ciara featuring Ludacris |
| May 21 | "Oh" | Ciara featuring Ludacris |
| May 28 | "We Belong Together" | Mariah Carey |
| June 4 | "We Belong Together" | Mariah Carey |
| June 11 | "We Belong Together" | Mariah Carey |
| June 18 | "We Belong Together" | Mariah Carey |
| June 25 | "We Belong Together" | Mariah Carey |
| July 2 | "We Belong Together" | Mariah Carey |
| July 9 | "We Belong Together" | Mariah Carey |
| July 16 | "We Belong Together" | Mariah Carey |
| July 23 | "We Belong Together" | Mariah Carey |
| July 30 | "We Belong Together" | Mariah Carey |
| August 6 | "We Belong Together" | Mariah Carey |
| August 13 | "We Belong Together" | Mariah Carey |
| August 20 | "We Belong Together" | Mariah Carey |
| August 27 | "We Belong Together" | Mariah Carey |
| September 3 | "We Belong Together" | Mariah Carey |
| September 10 | "We Belong Together" | Mariah Carey |
| September 17 | "Shake It Off" | Mariah Carey |
| September 24 | "Shake It Off" | Mariah Carey |
| October 1 | "Shake It Off" | Mariah Carey |
| October 8 | "Gold Digger" | Kanye West featuring Jamie Foxx |
| October 15 | "Gold Digger" | Kanye West featuring Jamie Foxx |
| October 22 | "Gold Digger" | Kanye West featuring Jamie Foxx |
| October 29 | "Gold Digger" | Kanye West featuring Jamie Foxx |
| November 5 | "Gold Digger" | Kanye West featuring Jamie Foxx |
| November 12 | "Run It!" | Chris Brown |
| November 19 | "Run It!" | Chris Brown |
| November 26 | "Run It!" | Chris Brown |
| December 3 | "Run It!" | Chris Brown |
| December 10 | "Run It!" | Chris Brown |
| December 17 | "Run It!" | Chris Brown |
| December 24 | "Run It!" | Chris Brown |
| December 31 | "Don't Forget About Us" | Mariah Carey |
| 2006 ||||
| January 7 | "Don't Forget About Us" | Mariah Carey |
| January 14 | "Don't Forget About Us" | Mariah Carey |
| January 21 | "Don't Forget About Us" | Mariah Carey |
| January 28 | "Don't Forget About Us" | Mariah Carey |
| February 4 | "Check on It" | Beyoncé featuring Slim Thug |
| February 11 | "Check on It" | Beyoncé featuring Slim Thug |
| February 18 | "Check on It" | Beyoncé featuring Slim Thug |
| February 25 | "Be Without You" | Mary J. Blige |
| March 4 | "Be Without You" | Mary J. Blige |
| March 11 | "Be Without You" | Mary J. Blige |
| March 18 | "Be Without You" | Mary J. Blige |
| March 25 | "Be Without You" | Mary J. Blige |
| April 1 | "Be Without You" | Mary J. Blige |
| April 8 | "Be Without You" | Mary J. Blige |
| April 15 | "Be Without You" | Mary J. Blige |
| April 22 | "Be Without You" | Mary J. Blige |
| April 29 | "Temperature" | Sean Paul |
| May 6 | "Temperature" | Sean Paul |
| May 13 | "Temperature" | Sean Paul |
| May 20 | "Temperature" | Sean Paul |
| May 27 | "Hips Don't Lie" | Shakira featuring Wyclef Jean |
| June 3 | "Hips Don't Lie" | Shakira featuring Wyclef Jean |
| June 10 | "Hips Don't Lie" | Shakira featuring Wyclef Jean |
| June 17 | "Ridin'" | Chamillionaire featuring Krayzie Bone |
| June 24 | "Ridin'" | Chamillionaire featuring Krayzie Bone |
| July 1 | "It's Goin' Down" | Yung Joc |
| July 8 | "It's Goin' Down" | Yung Joc |
| July 15 | "It's Goin' Down" | Yung Joc |
| July 22 | "It's Goin' Down" | Yung Joc |
| July 29 | "Me & U" | Cassie |
| August 5 | "Me & U" | Cassie |
| August 12 | "Me & U" | Cassie |
| August 19 | "Me & U" | Cassie |
| August 26 | "Me & U" | Cassie |
| September 2 | "Me & U" | Cassie |
| September 9 | "Me & U" | Cassie |
| September 16 | "(When You Gonna) Give It Up to Me" | Sean Paul featuring Keyshia Cole |
| September 23 | "Pullin' Me Back" | Chingy featuring Tyrese |
| September 30 | "SexyBack" | Justin Timberlake |
| October 7 | "SexyBack" | Justin Timberlake |
| October 14 | "SexyBack" | Justin Timberlake |
| October 21 | "SexyBack" | Justin Timberlake |
| October 28 | "Money Maker" | Ludacris featuring Pharrell |
| November 4 | "Money Maker" | Ludacris featuring Pharrell |
| November 11 | "My Love" | Justin Timberlake featuring T.I. |
| November 18 | "My Love" | Justin Timberlake featuring T.I. |
| November 25 | "My Love" | Justin Timberlake featuring T.I. |
| December 2 | "My Love" | Justin Timberlake featuring T.I. |
| December 9 | "My Love" | Justin Timberlake featuring T.I. |
| December 16 | "Irreplaceable" | Beyoncé |
| December 23 | "Irreplaceable" | Beyoncé |
| December 30 | "Irreplaceable" | Beyoncé |
| 2007 ||||
| January 6 | "Irreplaceable" | Beyoncé |
| January 13 | "Irreplaceable" | Beyoncé |
| January 20 | "Irreplaceable" | Beyoncé |
| January 27 | "Irreplaceable" | Beyoncé |
| February 3 | "Irreplaceable" | Beyoncé |
| February 10 | "Irreplaceable" | Beyoncé |
| February 17 | "Irreplaceable" | Beyoncé |
| February 24 | "Irreplaceable" | Beyoncé |
| March 3 | "Runaway Love" | Ludacris featuring Mary J. Blige |
| March 10 | "Runaway Love" | Ludacris featuring Mary J. Blige |
| March 17 | "You" | Lloyd featuring Lil Wayne |
| March 24 | "This Is Why I'm Hot" | Mims |
| March 31 | "This Is Why I'm Hot" | Mims |
| April 7 | "Don't Matter" | Akon |
| April 14 | "Don't Matter" | Akon |
| April 21 | "Don't Matter" | Akon |
| April 28 | "Don't Matter" | Akon |
| May 5 | "Don't Matter" | Akon |
| May 12 | "Don't Matter" | Akon |
| May 19 | "Buy U a Drank (Shawty Snappin')" | T-Pain featuring Yung Joc |
| May 26 | "Buy U a Drank (Shawty Snappin')" | T-Pain featuring Yung Joc |
| June 2 | "Buy U a Drank (Shawty Snappin')" | T-Pain featuring Yung Joc |
| June 9 | "Buy U a Drank (Shawty Snappin')" | T-Pain featuring Yung Joc |
| June 16 | "Buy U a Drank (Shawty Snappin')" | T-Pain featuring Yung Joc |
| June 23 | "Buy U a Drank (Shawty Snappin')" | T-Pain featuring Yung Joc |
| June 30 | "Buy U a Drank (Shawty Snappin')" | T-Pain featuring Yung Joc |
| July 7 | "Buy U a Drank (Shawty Snappin')" | T-Pain featuring Yung Joc |
| July 14 | "Umbrella" | Rihanna featuring Jay-Z |
| July 21 | "Umbrella" | Rihanna featuring Jay-Z |
| July 28 | "Umbrella" | Rihanna featuring Jay-Z |
| August 4 | "Umbrella" | Rihanna featuring Jay-Z |
| August 11 | "Beautiful Girls" | Sean Kingston |
| August 18 | "Big Girls Don't Cry" | Fergie |
| August 25 | "Big Girls Don't Cry" | Fergie |
| September 1 | "Big Girls Don't Cry" | Fergie |
| September 8 | "Big Girls Don't Cry" | Fergie |
| September 15 | "Big Girls Don't Cry" | Fergie |
| September 22 | "Big Girls Don't Cry" | Fergie |
| September 29 | "Big Girls Don't Cry" | Fergie |
| October 6 | "Stronger" | Kanye West |
| October 13 | "Crank That (Soulja Boy)" | Soulja Boy Tell 'Em |
| October 20 | "Crank That (Soulja Boy)" | Soulja Boy Tell 'Em |
| October 27 | "Crank That (Soulja Boy)" | Soulja Boy Tell 'Em |
| November 3 | "No One" | Alicia Keys |
| November 10 | "No One" | Alicia Keys |
| November 17 | "No One" | Alicia Keys |
| November 24 | "No One" | Alicia Keys |
| December 1 | "No One" | Alicia Keys |
| December 8 | "No One" | Alicia Keys |
| December 15 | "No One" | Alicia Keys |
| December 22 | "No One" | Alicia Keys |
| December 29 | "No One" | Alicia Keys |
| 2008 ||||
| January 5 | "No One" | Alicia Keys |
| January 12 | "No One" | Alicia Keys |
| January 19 | "No One" | Alicia Keys |
| January 26 | "No One" | Alicia Keys |
| February 2 | "No One" | Alicia Keys |
| February 9 | "Low" | Flo Rida featuring T-Pain |
| February 16 | "Low" | Flo Rida featuring T-Pain |
| February 23 | "Low" | Flo Rida featuring T-Pain |
| March 1 | "Low" | Flo Rida featuring T-Pain |
| March 8 | "With You" | Chris Brown |
| March 15 | "With You" | Chris Brown |
| March 22 | "With You" | Chris Brown |
| March 29 | "With You" | Chris Brown |
| April 5 | "With You" | Chris Brown |
| April 12 | "With You" | Chris Brown |
| April 19 | "Love in This Club" | Usher featuring Young Jeezy |
| April 26 | "Love in This Club" | Usher featuring Young Jeezy |
| May 3 | "Love in This Club" | Usher featuring Young Jeezy |
| May 10 | "Love in This Club" | Usher featuring Young Jeezy |
| May 17 | "Lollipop" | Lil' Wayne featuring Static Major |
| May 24 | "Lollipop" | Lil' Wayne featuring Static Major |
| May 31 | "Lollipop" | Lil' Wayne featuring Static Major |
| June 7 | "Lollipop" | Lil' Wayne featuring Static Major |
| June 14 | "Lollipop" | Lil' Wayne featuring Static Major |
| June 21 | "Lollipop" | Lil' Wayne featuring Static Major |
| June 28 | "Lollipop" | Lil' Wayne featuring Static Major |
| July 5 | "Lollipop" | Lil' Wayne featuring Static Major |
| July 12 | "Lollipop" | Lil' Wayne featuring Static Major |
| July 19 | "Lollipop" | Lil' Wayne featuring Static Major |
| July 26 | "Take A Bow" | Rihanna |
| August 2 | "Take A Bow" | Rihanna |
| August 9 | "Take A Bow" | Rihanna |
| August 16 | "Take A Bow" | Rihanna |
| August 23 | "Take A Bow" | Rihanna |
| August 30 | "Take A Bow" | Rihanna |
| September 6 | "Forever" | Chris Brown |
| September 13 | "Forever" | Chris Brown |
| September 20 | "Forever" | Chris Brown |
| September 27 | "Closer" | Ne-Yo |
| October 4 | "Whatever You Like" | T.I. |
| October 11 | "Whatever You Like" | T.I. |
| October 18 | "Whatever You Like" | T.I. |
| October 25 | "Whatever You Like" | T.I. |
| November 1 | "Whatever You Like" | T.I. |
| November 8 | "Whatever You Like" | T.I. |
| November 15 | "Whatever You Like" | T.I. |
| November 22 | "Whatever You Like" | T.I. |
| November 29 | "Live Your Life" | T.I. featuring Rihanna |
| December 6 | "Live Your Life" | T.I. featuring Rihanna |
| December 13 | "Live Your Life" | T.I. featuring Rihanna |
| December 20 | "Live Your Life" | T.I. featuring Rihanna |
| December 27 | "Live Your Life" | T.I. featuring Rihanna |
| 2009 ||||
| January 3 | "Live Your Life" | T.I. featuring Rihanna |
| January 10 | "Live Your Life" | T.I. featuring Rihanna |
| January 17 | "Live Your Life" | T.I. featuring Rihanna |
| January 24 | "Single Ladies (Put a Ring on It)" | Beyoncé |
| January 31 | "Single Ladies (Put a Ring on It)" | Beyoncé |
| February 7 | "Single Ladies (Put a Ring on It)" | Beyoncé |
| February 14 | "Single Ladies (Put a Ring on It)" | Beyoncé |
| February 21 | "Single Ladies (Put a Ring on It)" | Beyoncé |
| February 28 | "Heartless" | Kanye West |
| March 7 | "Heartless" | Kanye West |
| March 14 | "Dead and Gone" | T.I. featuring Justin Timberlake |
| March 21 | "Dead and Gone" | T.I. featuring Justin Timberlake |
| March 28 | "Dead and Gone" | T.I. featuring Justin Timberlake |
| April 4 | "Dead and Gone" | T.I. featuring Justin Timberlake |
| April 11 | "Dead and Gone" | T.I. featuring Justin Timberlake |
| April 18 | "Dead and Gone" | T.I. featuring Justin Timberlake |
| April 25 | "Dead and Gone" | T.I. featuring Justin Timberlake |
| May 2 | "Blame It" | Jamie Foxx featuring T-Pain |
| May 9 | "Blame It" | Jamie Foxx featuring T-Pain |
| May 16 | "Blame It" | Jamie Foxx featuring T-Pain |
| May 23 | "Blame It" | Jamie Foxx featuring T-Pain |
| May 30 | "Boom Boom Pow" | The Black Eyed Peas |
| June 6 | "Boom Boom Pow" | The Black Eyed Peas |
| June 13 | "Boom Boom Pow" | The Black Eyed Peas |
| June 20 | "Boom Boom Pow" | The Black Eyed Peas |
| June 27 | "Boom Boom Pow" | The Black Eyed Peas |
| July 4 | "Knock You Down" | Keri Hilson featuring Kanye West and Ne-Yo |
| July 11 | "Knock You Down" | Keri Hilson featuring Kanye West and Ne-Yo |
| July 18 | "Knock You Down" | Keri Hilson featuring Kanye West and Ne-Yo |
| July 25 | "Knock You Down" | Keri Hilson featuring Kanye West and Ne-Yo |
| August 1 | "Knock You Down" | Keri Hilson featuring Kanye West and Ne-Yo |
| August 8 | "Best I Ever Had" | Drake |
| August 15 | "Best I Ever Had" | Drake |
| August 22 | "I Gotta Feeling" | The Black Eyed Peas |
| August 29 | "I Gotta Feeling" | The Black Eyed Peas |
| September 5 | "I Gotta Feeling" | The Black Eyed Peas |
| September 12 | "I Gotta Feeling" | The Black Eyed Peas |
| September 19 | "I Gotta Feeling" | The Black Eyed Peas |
| September 26 | "I Gotta Feeling" | The Black Eyed Peas |
| October 3 | "You Belong With Me" | Taylor Swift |
| October 10 | "You Belong With Me" | Taylor Swift |
| October 17 | "Down" | Jay Sean featuring Lil' Wayne |
| October 24 | "Down" | Jay Sean featuring Lil' Wayne |
| October 31 | "Down" | Jay Sean featuring Lil' Wayne |
| November 7 | "Down" | Jay Sean featuring Lil' Wayne |
| November 14 | "Down" | Jay Sean featuring Lil' Wayne |
| November 21 | "Paparazzi" | Lady Gaga |
| November 28 | "Empire State of Mind" | Jay-Z and Alicia Keys |
| December 5 | "Empire State of Mind" | Jay-Z and Alicia Keys |
| December 12 | "Empire State of Mind" | Jay-Z and Alicia Keys |
| December 19 | "Empire State of Mind" | Jay-Z and Alicia Keys |
| December 26 | "Empire State of Mind" | Jay-Z and Alicia Keys |

## Statistics
### Artists by total number-one singles

| Artist | Number-one singles |
| Usher | 6 |
| Beyoncé | 5 |
| 50 Cent | 5 |
| Ludacris | 5 |
| Kanye West | 5 |
| Alicia Keys | 4 |
| T.I. | 4 |
| Destiny's Child | 4 |
| Sean Paul | 4 |
| Jennifer Lopez | 4 |

### Artists by total cumulative weeks at number one

| Artist | Number-one singles |
| Usher | 43 |
| Beyoncé | 36 |
| Alicia Keys | 35 |
| T.I. | 28 |
| Mariah Carey | 24 |
| 50 Cent | 23 |
| Nelly | 23 |
| Destiny's Child | 22 |
| Jay-Z | 21 |
| Ludacris | 19 |

### Songs by total number of weeks at number one

| Song | Artist(s) | Weeks at number one |
| "We Belong Together" | Mariah Carey | 16 |
| "No One" | Alicia Keys | 14 |
| "Dilemma" | Nelly featuring Kelly Rowland | 12 |
| "Yeah!" | Usher featuring Lil Jon and Ludacris | 12 |
| "Lose Yourself" | Eminem | 11 |
| "Let Me Love You" | Mario | 11 |
| "Irreplaceable" | Beyoncé | 11 |
| "U Got It Bad" | Usher | 10 |
| "Foolish" | Ashanti | 10 |
| "Lollipop" | Lil' Wayne featuring Static Major | 10 |