# List of ambassadors of the United States to Uruguay

The following is a list of United States ambassadors, or other chiefs of mission, to Uruguay. The current title given by the United States State Department to this position is Ambassador Extraordinary and Minister Plenipotentiary.
| Representative | Title | Presentation of credentials | Termination of mission | Appointed by |
| Alexander Asboth | Minister Resident | October 2, 1867 | January 21, 1868 | Andrew Johnson |
| Henry G. Worthington | Minister Resident | October 24, 1868 | July 10, 1869 | Andrew Johnson |
| Robert C. Kirk | Minister Resident | July 24, 1869 | July 6, 1870 | Ulysses S. Grant |
| John L. Stevens | Minister Resident | July 6, 1870 | May 19, 1873 | Ulysses S. Grant |
| John C. Caldwell | Minister Resident | September 7, 1874 | October 6, 1876 | Ulysses S. Grant |
| John C. Caldwell | Chargé d'Affaires | October 6, 1876 | July 10, 1882 | Ulysses S. Grant |
| William Williams | Chargé d'Affaires | July 10, 1882 | July 21, 1885 | Chester A. Arthur |
| John E. Bacon | Chargé d'Affaires | July 21, 1885 | October 8, 1888 | Grover Cleveland |
| John E. Bacon | Minister Resident | October 8, 1888 | December 26, 1888 | Grover Cleveland |
| George Maney | Minister Resident | November 8, 1889 | November 28, 1890 | Benjamin Harrison |
| George Maney | Envoy Extraordinary and Minister Plenipotentiary | November 28, 1890 | June 30, 1894 | Benjamin Harrison |
| Granville Stuart | Envoy Extraordinary and Minister Plenipotentiary | July 2, 1894 | January 4, 1898 | Grover Cleveland |
| William R. Finch | Envoy Extraordinary and Minister Plenipotentiary | January 4, 1898 | May 29, 1905 | William McKinley |
| Edward C. O'Brien | Envoy Extraordinary and Minister Plenipotentiary | June 2, 1905 | October 11, 1909 | Theodore Roosevelt |
| Edwin V. Morgan | Envoy Extraordinary and Minister Plenipotentiary | March 31, 1910 | July 8, 1911 | William H. Taft |
| Nicolai A. Grevstad | Envoy Extraordinary and Minister Plenipotentiary | October 9, 1911 | February 19, 1915 | William H. Taft |
| Robert Emmett Jeffery | Envoy Extraordinary and Minister Plenipotentiary | June 4, 1915 | March 9, 1921 | Woodrow Wilson |
| Hoffman Philip | Envoy Extraordinary and Minister Plenipotentiary | September 19, 1922 | April 10, 1925 | Warren G. Harding |
| Ulysses Grant-Smith | Envoy Extraordinary and Minister Plenipotentiary | July 13, 1925 | January 11, 1929 | Calvin Coolidge |
| Leland Harrison | Envoy Extraordinary and Minister Plenipotentiary | April 11, 1930 | October 9, 1930 | Herbert Hoover |
| J. Butler Wright | Envoy Extraordinary and Minister Plenipotentiary | February 9, 1931 | July 10, 1934 | Herbert Hoover |
| Julius Gareché Lay | Envoy Extraordinary and Minister Plenipotentiary | May 20, 1935 | August 31, 1937 | Franklin D. Roosevelt |
| William Dawson | Envoy Extraordinary and Minister Plenipotentiary | February 10, 1938 | June 6, 1939 | Franklin D. Roosevelt |
| Edwin C. Wilson | Envoy Extraordinary and Minister Plenipotentiary | October 27, 1939 | March 5, 1941 | Franklin D. Roosevelt |
| William Dawson | Ambassador Extraordinary and Plenipotentiary | July 12, 1941 | August 6, 1946 | Franklin D. Roosevelt |
| Joseph F. McGurk | Ambassador Extraordinary and Plenipotentiary | November 28, 1946 | April 15, 1947 | Harry S. Truman |
| Ellis O. Briggs | Ambassador Extraordinary and Plenipotentiary | August 21, 1947 | August 6, 1949 | Harry S. Truman |
| Christian M. Ravndal | Ambassador Extraordinary and Plenipotentiary | September 9, 1949 | October 8, 1951 | Harry S. Truman |
| Edward L. Rodden | Ambassador Extraordinary and Plenipotentiary | December 27, 1951 | October 12, 1953 | Harry S. Truman |
| Dempster McIntosh | Ambassador Extraordinary and Plenipotentiary | November 12, 1953 | April 3, 1956 | Dwight D. Eisenhower |
| Jefferson Patterson | Ambassador Extraordinary and Plenipotentiary | May 2, 1956 | March 18, 1958 | Dwight D. Eisenhower |
| Robert F. Woodward | Ambassador Extraordinary and Plenipotentiary | April 21, 1958 | March 29, 1961 | Dwight D. Eisenhower |
| Edward J. Sparks | Ambassador Extraordinary and Plenipotentiary | May 24, 1961 | May 15, 1962 | John F. Kennedy |
| Wymberley DeRenne Coerr | Ambassador Extraordinary and Plenipotentiary | July 27, 1962 | January 22, 1965 | John F. Kennedy |
| Henry A. Hoyt | Ambassador Extraordinary and Plenipotentiary | June 14, 1965 | December 16, 1967 | Lyndon B. Johnson |
| Robert M. Sayre | Ambassador Extraordinary and Plenipotentiary | August 27, 1968 | October 19, 1969 | Lyndon B. Johnson |
| Charles W. Adair, Jr. | Ambassador Extraordinary and Plenipotentiary | November 13, 1969 | September 28, 1972 | Richard Nixon |
| Ernest V. Siracusa | Ambassador Extraordinary and Plenipotentiary | September 25, 1973 | April 22, 1977 | Richard Nixon |
| Lawrence Pezzulo | Ambassador Extraordinary and Plenipotentiary | August 10, 1977 | May 29, 1979 | Jimmy Carter |
| Lyle Franklin Lane | Ambassador Extraordinary and Plenipotentiary | October 17, 1979 | July 22, 1980 | Jimmy Carter |
| N. Shaw Smith | Chargé d'Affaires ad interim | July 22, 1980 | November 5, 1981 | Jimmy Carter |
| Thomas Aranda, Jr. | Ambassador Extraordinary and Plenipotentiary | November 5, 1981 | November 14, 1985 | Ronald Reagan |
| Malcolm Richard Wilkey | Ambassador Extraordinary and Plenipotentiary | November 28, 1985 | May 10, 1990 | Ronald Reagan |
| Richard C. Brown | Ambassador Extraordinary and Plenipotentiary | November 19, 1990 | August 19, 1993 | George H. W. Bush |
| Thomas J. Dodd, Jr. | Ambassador Extraordinary and Plenipotentiary | September 23, 1993 | September 1, 1997 | Bill Clinton |
| Christopher C. Ashby | Ambassador Extraordinary and Plenipotentiary | November 26, 1997 | March 1, 2001 | Bill Clinton |
| Martin J. Silverstein | Ambassador Extraordinary and Plenipotentiary | October 17, 2001 | July 6, 2005 | George W. Bush |
| Frank E. Baxter | Ambassador Extraordinary and Plenipotentiary | December 13, 2006 | January 20, 2009 | George W. Bush |
| David D. Nelson | Ambassador Extraordinary and Plenipotentiary | December 24, 2009 | May 23, 2011 | Barack Obama |
| Thomas H. Lloyd | Chargé d'Affaires a.i. | May 23, 2011 | May 10, 2012 |
| Julissa Reynoso | Ambassador Extraordinary and Plenipotentiary | May 10, 2012 | December 10, 2014 |
| Brad Freden | Chargé d'Affaires a.i. | December 10, 2014 | June 23, 2016 |
| Kelly Keiderling | Ambassador Extraordinary and Plenipotentiary | June 23, 2016 | June 29, 2019 | Barack Obama Donald Trump |
| Kenneth S. George | Ambassador Extraordinary and Plenipotentiary | September 2, 2019 | January 20, 2021 | Donald Trump |
| Jennifer Savage | Chargé d'Affaires | January 20, 2021 | July 10, 2022 | Joe Biden |
| Karl Ríos | Chargé d'Affaires | July 15, 2022 | March 22, 2023 | Joe Biden |
| Heide B. Fulton | Ambassador Extraordinary and Plenipotentiary | March 22, 2023 | Incumbent | Joe Biden |