# 2018 US Open – Mixed doubles

Martina Hingis and Jamie Murray were the defending champions, but Hingis retired from professional tennis at the end of 2017. Murray successfully defended his title alongside Bethanie Mattek-Sands, defeating Alicja Rosolska and Nikola Mektić, 2–6, 6–3, [11–9] to win the mixed doubles tennis title at the 2018 US Open.

## Seeds

* Gabriela Dabrowski / Mate Pavić (second round)
* Nicole Melichar / Oliver Marach (quarterfinals)
* Chan Hao-ching / Henri Kontinen (first round)
* Latisha Chan / Ivan Dodig (second round, withdrew)
* Andrea Sestini Hlaváčková / Édouard Roger-Vasselin (quarterfinals)
* Demi Schuurs / Matwé Middelkoop (first round)
* Katarina Srebotnik / Michael Venus (second round)
* Abigail Spears / Juan Sebastián Cabal (second round)

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Semifinals | Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final | Final |
| WC | Christina McHale Christian Harrison | 4 | 6 | [8] | | | | |
| | Bethanie Mattek-Sands Jamie Murray | 6 | 2 | [10] | | | | |
| | Bethanie Mattek-Sands Jamie Murray | 6 | 2 | [10] | Bethanie Mattek-Sands Jamie Murray | 2 | 6 | [11] |
| | | | | | Alicja Rosolska Nikola Mektić | 6 | 3 | [9] |
| | Alicja Rosolska Nikola Mektić | 2 | 6 | [10] | Alicja Rosolska Nikola Mektić | 6 | 3 | [9] |
| | Zhang Shuai John Peers | 6 | 4 | [7] | | | | |

### Top half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 1 | G Dabrowski M Pavić | 6 | 6 | | | | | | | | | | | | | | | |
| WC | J Loeb N Rubin | 0 | 4 | | 1 | G Dabrowski M Pavić | 5 | 3 | | | | | | | | | | |
| WC | C McHale C Harrison | 3 | 7 | [10] | WC | C McHale C Harrison | 7 | 6 | | | | | | | | | | |
| | V King N Monroe | 6 | 5 | [5] | | | | | WC | C McHale C Harrison | 6 | 6 | | | | | | |
| | K Peschke R Ram | 6 | 6 | | | | | | 5 | A Sestini Hlaváčková É Roger-Vasselin | 3 | 4 | | | | | | |
| | L Arruabarrena M López | 4 | 3 | | | K Peschke R Ram | 4 | 5 | | | | | | | | | | |
| | MJ Martínez Sánchez M Demoliner | 6$^8$ | 1 | | 5 | A Sestini Hlaváčková É Roger-Vasselin | 6 | 7 | | | | | | | | | | |
| 5 | A Sestini Hlaváčková É Roger-Vasselin | 7$^{10}$ | 6 | | | | | | | | | | | WC | C McHale C Harrison | 4 | 6 | [8] |
| 4 | L Chan I Dodig | 6 | 3 | [10] | | | | | | | | | | | B Mattek-Sands J Murray | 6 | 2 | [10] |
| | L Kichenok A Sitak | 4 | 6 | [8] | 4 | L Chan I Dodig | | | | | | | | | | | | |
| WC | T Townsend D Young | 1 | 5 | | | N Kichenok W Koolhof | w/o | | | | | | | | | | | |
| | N Kichenok W Koolhof | 6 | 7 | | | | | | | N Kichenok W Koolhof | 6$^5$ | 7$^8$ | [7] | | | | | |
| | B Mattek-Sands J Murray | 6 | 7$^7$ | | | | | | | B Mattek-Sands J Murray | 7$^7$ | 6$^6$ | [10] | | | | | |
| WC | A Anisimova M Mmoh | 4 | 6$^2$ | | | B Mattek-Sands J Murray | 6 | 7$^7$ | | | | | | | | | | |
| WC | K Christian J Cerretani | 7 | 3 | [6] | 8 | A Spears JS Cabal | 4 | 6$^2$ | | | | | | | | | | |
| 8 | A Spears JS Cabal | 5 | 6 | [10] | | | | | | | | | | | | | | |

### Bottom half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 7 | K Srebotnik M Venus | 6 | 6 | | | | | | | | | | | | | | | |
| PR | L Siegemund R Bopanna | 4 | 4 | | 7 | K Srebotnik M Venus | 6 | 4 | [14] | | | | | | | | | |
| | R Olaru F Škugor | 3 | 6 | [10] | | R Olaru F Škugor | 4 | 6 | [16] | | | | | | | | | |
| WC | D Collins T Fawcett | 6 | 4 | [3] | | | | | | | R Olaru F Škugor | 6$^5$ | 4 | | | | | |
| | M Ninomiya B McLachlan | 6 | 2 | [6] | | | | | | | A Rosolska N Mektić | 7$^7$ | 6 | | | | | |
| | A Rosolska N Mektić | 4 | 6 | [10] | | A Rosolska N Mektić | 6 | 6 | | | | | | | | | | |
| WC | C Gauff C Eubanks | 6 | 6 | | WC | C Gauff C Eubanks | 2 | 1 | | | | | | | | | | |
| 3 | H-c Chan H Kontinen | 4 | 4 | | | | | | | | | | | | A Rosolska N Mektić | 2 | 6 | [10] |
| 6 | D Schuurs M Middelkoop | 6 | 3 | [8] | | | | | | | | | | | S Zhang J Peers | 6 | 4 | [7] |
| | S Zhang J Peers | 4 | 6 | [10] | | S Zhang J Peers | 6 | 6 | | | | | | | | | | |
| | E Svitolina B Soares | 7 | 4 | [13] | | E Svitolina B Soares | 3 | 3 | | | | | | | | | | |
| | L Hradecká R Jebavý | 5 | 6 | [11] | | | | | | | S Zhang J Peers | 3 | 7$^9$ | [11] | | | | |
| | R Atawo A-u-H Qureshi | 3 | 2 | | | | | | | 2 | N Melichar O Marach | 6 | 6$^7$ | [9] | | | | |
| | A-L Grönefeld S González | 6 | 6 | | | A-L Grönefeld S González | 4 | 4 | | | | | | | | | | |
| WC | W Osuigwe F Tiafoe | 5 | 1 | | 2 | N Melichar O Marach | 6 | 6 | | | | | | | | | | |
| 2 | N Melichar O Marach | 7 | 6 | | | | | | | | | | | | | | | |