# List of ambassadors of the United States to Guyana

The following is a list of ambassadors of the United States to Guyana. The current title given by the United States State Department to this position is Ambassador Extraordinary and Minister Plenipotentiary.
| Representative | Title | Presentation of credentials | Termination of mission | Appointed by |
| Delmar R. Carlson | Chargé d'Affaires ad interim | May 26, 1966 | August 17, 1966 | Lyndon B. Johnson |
| Delmar R. Carlson | Ambassador Extraordinary and Plenipotentiary | August 17, 1966 | September 13, 1969 | Lyndon B. Johnson |
| Spencer Matthews King | Ambassador Extraordinary and Plenipotentiary | October 15, 1969 | March 8, 1974 | Richard Nixon |
| Max V. Krebs | Ambassador Extraordinary and Plenipotentiary | April 4, 1974 | June 15, 1976 | Richard Nixon |
| John R. Burke | Ambassador Extraordinary and Plenipotentiary | September 30, 1977 | September 22, 1979 | Jimmy Carter |
| George B. Roberts Jr. | Ambassador Extraordinary and Plenipotentiary | November 5, 1979 | September 8, 1981 | Jimmy Carter |
| Gerald Eustis Thomas | Ambassador Extraordinary and Plenipotentiary | February 18, 1982 | September 6, 1983 | Ronald Reagan |
| Clint Arlen Lauderdale | Ambassador Extraordinary and Plenipotentiary | August 2, 1984 | June 11, 1987 | Ronald Reagan |
| Theresa Anne Tull | Ambassador Extraordinary and Plenipotentiary | September 18, 1987 | July 10, 1990 | Ronald Reagan |
| Dennis K. Hays | Chargé d'Affaires ad interim | July 10, 1990 | January 21, 1992 | George H. W. Bush |
| George Fleming Jones | Ambassador Extraordinary and Plenipotentiary | January 21, 1992 | August 25, 1995 | George H. W. Bush |
| David L. Hobbs | Ambassador Extraordinary and Plenipotentiary | November 2, 1995 | September 15, 1996 | Bill Clinton |
| Hugh Simon | Chargé d'Affaires ad interim | September 15, 1996 | September 25, 1997 | Bill Clinton |
| James F. Mack | Ambassador Extraordinary and Plenipotentiary | September 25, 1997 | April 21, 2000 | Bill Clinton |
| Ronald D. Godard | Ambassador Extraordinary and Plenipotentiary | January 29, 2001 | July 6, 2003 | George W. Bush |
| Roland W. Bullen | Ambassador Extraordinary and Plenipotentiary | August 14, 2003 | July 14, 2006 | George W. Bush |
| David M. Robinson | Ambassador Extraordinary and Plenipotentiary | August 26, 2006 | March 16, 2008 | George W. Bush |
| John Melvin Jones | Ambassador Extraordinary and Plenipotentiary | July 21, 2008 | December 31, 2009 | George W. Bush |
| Thomas C. Pierce | Chargé d'Affaires ad interim | August 31, 2010 | September 15, 2011 | Barack Obama |
| D. Brent Hardt | Ambassador Extraordinary and Plenipotentiary | September 15, 2011 | July 6, 2014 | Barack Obama |
| Perry L. Holloway | Ambassador Extraordinary and Plenipotentiary | October 2, 2015 | December 8, 2018 | Barack Obama |
| Terry Steers-Gonzalez | Chargé d'Affaires ad interim | January 2019 | March 13, 2019 | Donald Trump |
| Sarah-Ann Lynch | Ambassador Extraordinary and Plenipotentiary | March 13, 2019 | September 12, 2023 | Donald Trump |
| Adrienne Galanek | Chargé d'Affaires ad interim | September 13, 2023 | October 23, 2023 | Joe Biden |
| Nicole D. Theriot | Ambassador Extraordinary and Plenipotentiary | October 23, 2023 | Incumbent | Joe Biden |