# Peppermint

Peppermint (Mentha × piperita) is a hybrid species of mint, a cross between watermint and spearmint. Indigenous to Europe and the Middle East, the plant is now widely spread and cultivated in many regions of the world. It is occasionally found in the wild with its parent species.
Although the genus Mentha comprises more than 25 species, the one in most common use is peppermint. While Western peppermint is derived from Mentha × piperita, Chinese peppermint, or bohe, is derived from the fresh leaves of M. haplocalyx. M. × piperita and M. haplocalyx are both recognized as plant sources of menthol and menthone, and are among the oldest herbs used for both culinary and medicinal products.

## Botany

Peppermint was first identified in Hertfordshire, England, by a Dr. Eales, a discovery which John Ray published 1696 in the second edition of his book Synopsis Methodica Stirpium Britannicarum. He initially gave it the name Mentha spicis brevioribus et habitioribus, foliis Mentha fusca, sapore fervido piperis and later in his 1704 volume Historia Plantarum he called it Mentha palustris or Peper–Mint. The plant was then added to the London Pharmacopoeia under the name Mentha piperitis sapore in 1721.
It was given the name Mentha piperita in 1753 by Carl Linnaeus in his Species Plantarum Volume 2. Linnaeus treated peppermint as a species, but it is now universally agreed to be a hybrid between Mentha viridis and Mentha aquatica with Mentha viridis itself also being a hybrid between Mentha sylvestris and Mentha rotundifolis.
Peppermint is an herbaceous, rhizomatous, perennial plant that grows to be 30–90 cm (12–35 in) tall, with smooth stems, square in cross section. The rhizomes are wide-spreading and fleshy, and bear fibrous roots. The leaves can be 4–9 cm (1+1⁄2–3+1⁄2 in) long and 1.5–4 cm (1⁄2–1+1⁄2 in) broad. They are dark green with reddish veins, with an acute apex and coarsely toothed margins. The leaves and stems are usually slightly fuzzy. The flowers are purple, 6–8 mm (1⁄4–5⁄16 in) long, with a four-lobed corolla about 5 mm (3⁄16 in) diameter; they are produced in whorls (verticillasters) around the stem, forming thick, blunt spikes.
Flowering season lasts from mid- to late summer. The chromosome number is variable, with 2n counts of 66, 72, 84, and 120 recorded. Peppermint is a fast-growing plant, spreading quickly once it has sprouted.

## Ecology

Peppermint typically occurs in moist habitats, including stream sides and drainage ditches. Being a hybrid, it is usually sterile, producing no seeds and reproducing only vegetatively, spreading by its runners.
Outside of its native range, areas where peppermint was formerly grown for oil often have an abundance of feral plants, and it is considered invasive in Australia, the Galápagos Islands, New Zealand, and the United States in the Great Lakes region, noted since 1843.

## Cultivation

Peppermint generally grows best in moist, shaded locations, and expands by underground rhizomes. Young shoots are taken from old stocks and dibbled into the ground about 0.5 m (1.5 ft) apart. They grow quickly and cover the ground with runners if it is permanently moist. For the home gardener, it is often grown in containers to restrict rapid spreading. It grows best with a good supply of water, without being water-logged, and planted in areas with partial sun to shade.
The leaves and flowering tops are used; they are collected as soon as the flowers begin to open and can be dried. The wild form of the plant is less suitable for this purpose, with cultivated plants having been selected for more and better oil content. They may be allowed to lie and wilt a little before distillation, or they may be taken directly to the still.

### Cultivars

Several cultivars have been selected for garden use:
* Mentha × piperita 'Candymint' has reddish stems.
* Mentha × piperita 'Chocolate Mint'. Its flowers open from the bottom up; its flavour is reminiscent of the flavour in Andes Chocolate Mints, a popular confection.
* Mentha × piperita 'Citrata' includes a number of varieties including Eau de Cologne mint, grapefruit mint, lemon mint, and orange mint. Its leaves are aromatic and hairless.
* Mentha × piperita 'Crispa' has wrinkled leaves.
* Mentha × piperita 'Lavender Mint'
* Mentha × piperita 'Lime Mint' has lime-scented foliage.
* Mentha × piperita 'Variegata' has mottled green and pale yellow leaves.
Commercial cultivars may include:
* Dulgo pole
* Zefir
* Bulgarian population #2
* Clone 11-6-22
* Clone 80-121-33
* Mitcham Digne 38
* Mitcham Ribecourt 19
* 'Todd's Mitcham', a verticillium wilt-resistant cultivar produced from a breeding and test program of atomic gardening at Brookhaven National Laboratory from the mid-1950s
* 'Refined Murray', also verticillium-resistant
* 'Roberts Mitcham', also verticillium-resistant and also the product of mutation breeding

### Diseases

Verticillium wilt is a major constraint in peppermint cultivation. 'Todd's Mitcham', 'Refined Murray', 'Roberts Mitcham' (see above), and a few other cultivars have some degree of resistance.
Peppermint production 2022, in tonnes :
| Morocco | 42,898 |
| Argentina | 6,977 |
| Mexico | 1,173 |
| World | 51,081 |
| Source: FAOSTAT of the United Nations ||

## Production

In 2022, world production of peppermint was 51,081 tonnes, led by Morocco with 84% of the total and Argentina with 14% (table).
In the United States, Oregon and Washington produce most of the country's peppermint, the leaves of which are processed for the essential oil to produce flavorings mainly for chewing gum and toothpaste.

## Chemical constituents

Peppermint has a high menthol content. The essential oil also contains menthone and carboxyl esters, particularly menthyl acetate. Dried peppermint typically has 0.3–0.4% of volatile oil containing menthol (7–48%), menthone (20–46%), menthyl acetate (3–10%), menthofuran (1–17%), and 1,8-cineol (3–6%). Peppermint oil also contains small amounts of many additional compounds, including limonene, pulegone, caryophyllene, and pinene.
Peppermint contains terpenoids and flavonoids such as eriocitrin, hesperidin, and kaempferol 7-O-rutinoside.

## Oil

Peppermint oil has a high concentration of natural pesticides, mainly pulegone (found mainly in M. arvensis var. piperascens (cornmint, field mint, or Japanese mint), and to a lesser extent (6,530 ppm) in Mentha × piperita subsp. notho) and menthone. It is known to repel some pest insects, including mosquitos, and has uses in organic gardening. It is also widely used to repel rodents.
The chemical composition of the essential oil from peppermint (Mentha × piperita L.) was analyzed by GC/FID and GC-MS. The main constituents were menthol (40.7%) and menthone (23.4%). Further components were (±)-menthyl acetate, 1,8-cineole, limonene, beta-pinene, and beta-caryophyllene.

## Research and health effects

Peppermint oil is under preliminary research for its potential as a short-term treatment for irritable bowel syndrome, and has supposed uses in traditional medicine for minor ailments. Peppermint oil and leaves have a cooling effect when used topically for muscle pain, nerve pain, relief from itching, or as a fragrance. High oral doses of peppermint oil (500 mg) can cause mucosal irritation and mimic heartburn.
Peppermint roots bioaccumulate radium, so the plant may be effective for phytoremediation of radioactively contaminated soil.

## Culinary and other uses

Fresh or dried peppermint leaves are often used alone in peppermint tea or with other herbs in herbal teas (tisanes, infusions). Peppermint is used for flavouring ice cream, candy, fruit preserves, alcoholic beverages, chewing gum, toothpaste, and some shampoos, soaps, and skin care products.
Menthol activates cold-sensitive TRPM8 receptors in the skin and mucosal tissues, and is the primary source of the cooling sensation that follows the topical application of peppermint oil.
* Candy canes are one of the most common peppermint-flavored candies.
* Mentha × piperita hybrid known as 'Chocolate Mint'
* Freeze-dried leaves
Peppermint oil is also used in construction and plumbing to test for the tightness of pipes and disclose leaks by its odor.

## Safety

Medicinal uses of peppermint have not been approved as effective or safe by the US Food and Drug Administration. With caution that the concentration of the peppermint constituent pulegone should not exceed 1% (140 mg), peppermint preparations are considered safe by the European Medicines Agency when used in topical formulations for adult subjects. Diluted peppermint essential oil is safe for oral intake when only a few drops are used.
Although peppermint is commonly available as a herbal supplement, no established, consistent manufacturing standards exist for it, and some peppermint products may be contaminated with toxic metals or other substituted compounds. Skin rashes, irritation, or allergic reactions may result from applying peppermint oil to the skin, and its use on the face or chest of young children may cause side effects if the oil menthol is inhaled. A common side effect from oral intake of peppermint oil or capsules is heartburn. Oral use of peppermint products may have adverse effects when used with iron supplements, cyclosporine, medicines for heart conditions or high blood pressure, or medicines to decrease stomach acid.

## Standardization

* ISO 676:1995—contains the information about the nomenclature of the variety and cultivars
* ISO 5563:1984—a specification for its dried leaves of Mentha piperita Linnaeus
* Peppermint oil—ISO 856:2006