OpenLLM-France/wikimedia huggingface dataset:
# Metabolic theory of cancer

The metabolic theory of cancer is the hypothesis that the primary cause of cancer is changes in cellular metabolism. The theory is strongly linked to the idea that diet can be used to prevent or treat many or most types of cancer. It is widely accepted that changes in cellular metabolism—specifically, an increased reliance on glucose for energy, and up-regulation of anabolic processes—do occur in many types of cancer cells. However, the idea that cancer can be controlled mostly or entirely by diet does not have broad acceptance in the medical field.

## Key principles of the metabolic theory of cancer

The metabolic theory of cancer is built upon several well-known biochemical differences between normal and rapidly-proliferating cells, including:
* The Warburg effect: In the 1920s, Otto Warburg observed that cancer cells prefer to generate energy through anaerobic fermentation, even when oxygen is plentiful. This is different from normal cells, which use oxygen-dependent oxidative phosphorylation for more efficient energy production. As a result, cancer cells rely heavily on glucose (sugar) for energy, and produce significant amounts of lactate.
* Mitochondrial dysfunction: Proponents of the metabolic theory argue that mitochondrial dysfunction plays a crucial role in cancer. Mitochondria are the cell’s energy factories and play a role in regulating cell death (apoptosis). Alterations in mitochondrial morphology are evident in several types of cancer cells.
* Metabolic flexibility and glutamine dependence: Cancer cells often rely on glutamine as an alternative energy source and as a building block for growth, especially when glucose is limited. This metabolic flexibility allows cancer cells to adapt and thrive under varying conditions, making them more resistant to standard treatments like chemotherapy.

## Therapeutic implications

Dietary approaches: Low-carbohydrate or ketogenic diets are suggested as potentially helpful because they limit glucose availability to cancer cells, thereby "starving" them. These diets force the body to produce ketones, which cancer cells cannot use.
Targeting metabolism in treatment: Drugs that disrupt cancer cells' metabolic processes, particularly those targeting glucose or glutamine metabolism, are being explored as cancer treatments.

## Controversy and research

The metabolic theory is still under investigation and remains controversial. While there is evidence supporting the role of altered metabolism in cancer, the genetic mutation model also has significant support. Many researchers are now examining cancer as a complex interplay of genetic mutations and metabolic dysregulation, rather than a purely genetic or purely metabolic disease.
# Fujimoto Kannonyama Kofun

The Fujimoto Kannonyama Kofun (藤本観音山古墳) is a "two conjoined rectangles" shaped (前方後方墳, zenpō-kōhō-fun [ja]) kofun burial mound located in the city of Ashikaga in Tochigi Prefecture in the northern Kantō region of Japan. It received protection as a National Historic Site in 2006.

## Overview

The Fujimoto Kannonyama Kofun is located in the Fujimoto neighborhood of Ashikaga City surrounded by rice fields, in the northern end of the Kantō Plain near the border with Gunma Prefecture. It is located on a plateau on the right bank of the Yaba River. The surrounding area has numerous smaller kofun and was densely settled in the ancient period.
The tumulus has a total length of 117.8 meters, and consists of a front part with two tiers and a height of 5.4 meters, and a back part with three tiers and a height of 11.8 meters. In the rear part, fukiishi covered the third tier, and although no haniwa were found, a clay pot with a double rim was placed on top of the mound. The tumulus was surrounded by a moat, and including the dimensions of the moat, the total length exceeds 210 meters. This is the fifth largest zenpō-kōhō-fun [ja] in Japan, and the third largest in eastern Japan. It dates from the middle of the 4th century, based on a pumice layer from a 4th century eruption of Mount Asama which was found in the topsoil beneath the tumulus.
The tumulus has not been excavated and the burial chamber appears to be intact, as no trace of digging has been detected. The first excavation survey was carried out in 1984, and further surveys were conducted for seven times by 2003. On the south side of tumulus, the remains of 21 pit dwellings and three storage pits dating from the same time as the kofun have been discovered. It is believed that this was a settlement either related to the construction of the tumulus, or connected to rituals associated with the kofun after its completion.
The kofun is located approximately a 30 minute walk from Fukui Station on the Tobu Isesaki Line.
# Shenzhou 17

Shenzhou 17 (Chinese: 神舟十七号; pinyin: Shénzhōu Shíqī-hào; lit. 'Divine Boat Number 17') was a Chinese spaceflight to the Tiangong space station, launched on 26 October 2023. It carried three People's Liberation Army Astronaut Corps (PLAAC) taikonauts on board a Shenzhou spacecraft. The mission was the twelfth crewed Chinese spaceflight and the seventeenth flight overall of the Shenzhou program.

## Background

Shenzhou 17 was the sixth spaceflight to the Tiangong space station, lasting just over six months.
The spacecraft entered the launch area in April 2023, prior to launch was maintained in a state of near-readiness if needed as a lifeboat for the Shenzhou 16 crew.
The crew of Shenzhou 17 was announced on 25 October 2023.

## Mission

The flight launched from Jiuquan Satellite Launch Center on 26 October 2023 at 09:46 UTC, near the end of the Shenzhou 16 mission. Approximately 6.5 hours after launch, the spacecraft docked with the Tianhe core module's forward docking port.
Following docking, the crew entered the station and were greeted by the crew of Shenzhou 16, with whom they would share a four-day overlap between the two missions prior to Shenzhou 16's departure. The two crews sent a televised message to Mission Control as part of a handover ceremony, which was also livestreamed by Chinese national television broadcaster CCTV.
The mission ended on 30 April 2024, 9:46 UTC with a landing near the launch site in Inner Mongolia.

### Spacewalks

On 21 December 2023, the first scheduled spacewalk of Shenzhou 17 was carried out by Tang Hongbo and Tang Shengjie through the airlock of the Wentian lab module. Tasks included a repair test of the Tianhe core module's solar panels, which have sustained minor damage caused by impacts of space debris and micrometeoroids. The spacewalk lasted for 7 hours and 25 minutes.
On 2 March 2024, the second scheduled spacewalk of Shenzhou 17 was carried out by Tang Hongbo and Jiang Xinlin through the airlock of the Wentian lab module. Tasks included maintenance of the solar panels of the Tianhe core module, evaluation and analysis of the performance status of the solar panel power generation and also inspection of the status of the space station modules. The spacewalk lasted for 7 hours and 52 minutes.

## Crew

| Position | Crew member | Crew member |
| Commander | Tang Hongbo, CMSA Second spaceflight | Tang Hongbo, CMSA Second spaceflight |
| Operator | Tang Shengjie, CMSA First spaceflight | Tang Shengjie, CMSA First spaceflight |
| Science Operator | Jiang Xinlin, CMSA First spaceflight | Jiang Xinlin, CMSA First spaceflight |
Commander Tang Hongbo is the first person to visit the station twice, having previously flown to Tiangong on Shenzhou 12. Tang Shengjie is also the youngest taikonaut to perform a spacewalk.
# Stoke Common

Stoke Common is an 83.1-hectare (205-acre) Site of Special Scientific Interest in Stoke Poges in Buckinghamshire. It is registered common land, and it is owned by a charitable trust, with the City of London Corporation as the main funder and trustee.
The site is a last remnant of a large heath, and is on glacial gravel over London clay, with some parts permanently waterlogged. Periodic burning helps to manage the land. There are small areas of birch, pine and mixed woodland, with several ponds. There is a rich invertebrate fauna, especially moths, and the dusky cockroach and rare bog bush cricket have also been recorded.
There is access from Stoke Common Road, Gerrards Cross Road and Windmill Road.
# Albert Houssiau

Albert Jean Charles Ghislain Houssiau (born 2 November 1924) is a Belgian prelate of the Catholic Church. He served as bishop of Liège from 1986 to 2001.
Houssiau was born in November 1924 and was ordained a priest on February 6, 1949. He was appointed bishop of Liège on March 17, 1986 by Pope John Paul II, and was consecrated on May 18, 1986. He held the post until his retirement on May 9, 2001.
# Civil Revolution

Civil Revolution (Italian: Rivoluzione Civile, RC) was a left-wing coalition of political parties in Italy.
The coalition was headed by Antonio Ingroia, a former anti-mafia prosecutor of Palermo from 1992 to 2012 and then director of a UN investigation into illegal drug trade in Guatemala in 2012.
The foundation of RC was preceded by the manifesto Io ci sto, presented by Ingroia on 21 December in Rome. Among the signatories of this appeal were Franco Battiato, Fiorella Mannoia, Luigi de Magistris, Leoluca Orlando, Milly Moratti, Massimiliano Bruno, Max Paiella, Sabina Guzzanti, Vauro and Enrico Fierro. The coalition had an anti-corruption platform.
In the 2013 general election the party obtained 2.2% of the vote, returning no seats in the Italian Parliament.
Soon after RC was dissolved on 2 April 2013, Ingroia launched a new party named Civil Action (Italian: Azione Civile).

## Overview

Civil Revolution was founded on 29 December 2012 in Rome by Ingroia and the following parties:
| Party | Ideology | Leader |
| Italy of Values (IdV) | Anti-corruption | Antonio Di Pietro |
| Communist Refoundation Party (PRC) | Communism | Paolo Ferrero |
| Party of Italian Communists (PdCI) | Communism | Oliviero Diliberto |
| Federation of the Greens (FdV) | Green politics | Angelo Bonelli |
| The Network 2018 (LR2018) | Anti-corruption | Leoluca Orlando |
| Orange Movement (MA) | Anti-corruption | Luigi de Magistris |
Subsequently, the following parties and organizations joined RC:
* Red Diaries (Agende Rosse - Anti-mafia politics), led by Salvatore Borsellino;
* We Can Change (Cambiare Si Può, CSP - Left-wing appeal), led by Livio Pepino, Marco Revelli and Chiara Sasso;
* Ecologists and Civic Networks (Ecologisti e Reti Civiche - Green coalition), led by Bonelli and Mary Luppino, including:
** Federation of the Greens (Federazione dei Verdi);
** We Have a Dream (Abbiamo un Sogno);
** Ecologist Constituent Assembly (Costituente Ecologista);
** Mayors of Good Administration (Sindaci della Buona Amministrazione);
* New Action Party (Nuovo Partito d'Azione, NPA - Social liberalism), led by Giuseppe Antonio Quartana;
* Purple People (Popolo Viola - Activism), led by Massimo Malerba.
* Party of the South (Partito del Sud - Southernism), led by Beppe De Santis.

## Electoral results
### Italian Parliament

Chamber of Deputies :
| Election year | # of overall votes | % of overall vote | # of overall seats won | +/– | Leader |
| 2013 | 765,172 | 2.25 | 0 / 630 | – | Antonio Ingroia |
Senate :
| Election year | # of overall votes | % of overall vote | # of overall seats won | +/– | Leader |
| 2013 | 549,987 | 1.79 | 0 / 315 | – | Antonio Ingroia |

## Leadership

* President: Antonio Ingroia (2012–2013)
# Kowloon Cricket Club

The Kowloon Cricket Club, also called KCC (Chinese: 九龍木球會), is a members only cricket club and social club situated in Kowloon, Hong Kong, on Cox's Road.

## History

The Cricket Club was established on 4 October 1904 and was provided land from the government in King's Park. It competed with local clubs like the Hong Kong Cricket Club, the Craigengower Cricket Club, the Parsee Cricket Club, Royal Engineers, the Army Ordnance Corps CC and the Civil Service CC Royal Army Medical Corps and HMS Tamar soldiers played with KCC in the South China Morning Post Shield.
The foundation stone of the first Clubhouse was laid on 18 January 1908 by the President and benefactor, Sir Hormusjee N. Mody, who was later presented with an engraved silver trowel to mark the occasion. The Kowloon Cricket Club Pavilion was opened by the Governor H.E. Sir Frederick Lugard on 11 July 1908.
Due to World War II, the club did not operate between 1941 and 1946.
The club competed for the Hancock Memorial Shield after 1946.
As of January 2016, its head coach is Ryan Campbell, who is also the batting coach of the Hong Kong national cricket team.

## Facilities

The KCC has its own cricket pitch.
Since 1992 it has been the venue of the Hong Kong Cricket Sixes (apart from the 1996 and 1997) editions. It also has a full-size bowling green.
# Osceola Public School Building

Osceola Public School Building, also known as Osceola High School Building, is a historic school building located at Osceola, St. Clair County, Missouri. The original section was built in 1914–1915, and is a three-story, brick and cut stone building. It features a segmental arched, recessed main entrance, located in a projecting centered bay. A two-story brick and cut stone addition designed by architect Charles A. Smith was added in 1937.
It was added to the National Register of Historic Places in 1999.
# Samakh raid (1920)

The Samakh raid was fought in April 1920 between Arab Bedouin irregulars under the banner of the Arab Kingdom of Syria and the British Army in Eastern Galilee. The event is perceived by scholars as part of the spillover of the Franco-Syrian War.

## Background

The Franco-Syrian War took place in early 1920 between Syrian Arab nationalists, under the Hashemite King, and France. Gangs ('isabat) of clan-based border peasants, combining politics and banditry, were active in the area of the loosely defined border between the soon to be established Mandatory Palestine, French Mandate of Lebanon and Syria.

## Timeline

At the beginning of the Franco-Syrian War, the Upper Galilee was populated by several semi-nomadic Bedouin Arab tribes, the largest residing in Halasa, and four tiny Jewish settlements, including Metula, Kfar Giladi, Tel Hai and Hamra. While the Arab villages and Bedouin allied with the Arab Kingdom of Syria, the Jewish residents chose to remain neutral during the Arab conflict with the French.
Just prior to the French occupation of Damascus, the instability in Transjordan threatened to spill over into Palestine. The sedentary clans of Bani Kananah, perhaps encouraged by members of the Istiqlal native to the Hawran, including such radical nationalists as Ahmad Muraywid and Ali Khulqi raided Jewish settlements in Galilee. Early in the war, a Kfar Giladi resident was killed by armed Bedouin, greatly increasing tension in the region. Jewish villages were regularly pillaged by the pro-Syrian Bedouin on the pretext of searching for French spies and soldiers.
In April 1920, the Arab militants engaged British Army at Samakh and suffered a number of casualties as RAF planes strafed them on their way back across the Jordan river. The event took place as some 2,000 armed Bedouins mostly from Transjordan attempted to attack the Samakh train station aiming to prevent the arrival of British reinforcements from Haifa.

## Consequences

The Samakh raid seemed to confirm Allenby's fears that abandonment of OETA East would leave Palestine's right flank "in the air, threatened by all the Druze and bedouin tribes." Herbert Samuel, the high commissioner in Jerusalem, called for the occupation of Transjordan west of the Hijaz Railway.
# Shams Azar F.C.

Shams Azar Football Club is an Iranian football club based in Qazvin, Iran. They currently compete in the Persian Gulf Pro League.

## History

Shams Azar is the first team of Qazvin Province after Paykan in the Iran Pro League. In September 2012, they bought the license of Kaveh football club in order to participate in 2013–14 Iran Football's 2nd Division. This team won the eighth place in the first season of its participation in the Persian Gulf League.

## Honours

* Azadegan League
** Champions (1): 2022–23

## Players
### First-team squad

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply. Players may hold more than one non-FIFA nationality.
| No. | Pos. | Nation | Player |
| 1 | GK | IRN | Mohammad Amin Rezaei |
| 2 | DF | IRN | Amirhossein Sedghi |
| 3 | DF | IRN | Mehdi Mohammadi (captain) |
| 5 | DF | IRN | Amir Shabani |
| 6 | DF | IRN | Mohammadhossein Rafiei |
| 7 | MF | IRN | Amir Mohammad Nesaei |
| 8 | MF | IRN | Khashayar Zebarjad |
| 9 | FW | IRN | Sina Hatami |
| 10 | MF | IRN | Ali Pouresmaeil |
| 11 | FW | IRN | Mojtaba Fakhrian |
| 12 | DF | IRN | Reza Mirahmadi |
| 16 | FW | IRN | Mohammad Milad Sourgi |
| 17 | FW | IRN | Ali Vaziri Panah |
| 18 | MF | IRN | Farhad Zavoshi |
| 19 | DF | IRN | Iman Akbari |
| No. | Pos. | Nation | Player |
| 20 | FW | IRN | Navid Komar |
| 22 | GK | IRN | Mohammadhossein Khodabakhshi |
| 23 | MF | IRN | Sadegh Albusabih |
| 26 | MF | IRN | Amirmehdi Din Mohammadi |
| 29 | FW | IRN | Mohammadmehdi Mansouri |
| 33 | DF | IRN | Hooman Rabizadeh |
| 34 | DF | IRN | Milad Fakhreddini |
| 44 | DF | IRN | Ali Malakoutikhah |
| 53 | GK | IRN | Omid Amiri |
| 66 | MF | IRN | Mohammadjavad Azadeh |
| 70 | DF | IRN | Amir Mohammad Panahi |
| 72 | MF | IRN | Sepehr Roozitalab |
| 77 | DF | IRN | Ali Azadmanesh |
| 84 | MF | IRN | Amirreza kalivand |
| 96 | FW | IRN | Hadi Maroufi |

## Technical staff

| Position | Staff |
| Head coach | Saeid Daghighi |
| Assistant Manager | Mehrdad Karimian |
| Fitness Coach | Yaser Jalali |
# Julia Glaser

Julia Glaser (born October 7, 1997) is a Swiss footballer who plays for VfB Stuttgart. She has previously played for Lazio and FC Basel.
# Mount Gilead High School

Mount Gilead High School is a public high school in Mount Gilead, Ohio. It is the only high school in the Mount Gilead Exempted Village Schools district. Their nickname is the Indians. The school currently is under superintendent Dr. Zack Howard. The school uses three buildings for students: Park Avenue, a K-5 building; Cherry Street (admin. bldg.), a middle school containing 6–8; and the High School, also located on Park Avenue. Over the past four years the Cross Country team has participated in the state tournament. In 2002 Jake Haughn won the Division III OHSAA 3200 Meter run title in track, at the time setting a new record. The School has a long-standing and fierce rivalry with Cardington-Lincoln High School.

## Ohio High School Athletic Association State Championships

* Boys Golf – 1985
* Boys Cross Country - State Champions 2022; State Runner-Up - 2019, 2021
* Girls Cross Country - State Runner-Up - 2017
* Boys Track - State Champion - 1970 Jerry Staley (180 Low Hurdles); 1974 Monty Ward (440 Dash); 1975 Monty Ward (440 Dash); 2002 Jake Haughn (3200m Run); 2009 Colton Johnson (Indoor 3200m Run); 2017 Austin Hallabrin (800m Run); 2019 Bradley Landon (Seated Shot Put)
* Girls Track - State Champion - 2019 Allison Johnson (800m Run); 2020 Kelsey Kennon (Indoor Shot Put); 2020 Allison Johnson (Indoor 800m Run); 2021 Allison Johnson (Indoor 800m Run); 2021 Allison Johnson (Indoor 1600m Run); 2021 Michaela McGill, Olivia Millisor, Emily Hanft, Allison Johnson (3200 Relay); 2021 Allison Johnson (800m Run); 2021 Allison Johnson (1600m Run)
* Girls Track Team State Runner Up - 2021
Ohio High School Athletic Association Conference Championships==
* Girls Basketball- Conference Champions 2023; District Final Runner-Up
# Bentot Jr.

Bentot Jr. (born Luisito "Louie" Garcia Medina; January 8, 1970 – May 2, 2016) was a Filipino actor, and the adopted son of the late comedian Bentot. He had an older brother, Nick Medina, who is also known as Bentot Jr.

## Background

Bentot Jr.'s first movie role was at the age of 3.5 years old and made 14 more movies up until 1985, when he left the film industry in favor of his studies. He returned to the industry in 2000 up to his last movie, Djagwar in 2011. He played Lando in Philippines' movie Panday. He made his first international appearance in the Bruceploitation movie The Return of Bruce with Bruce Le and Elizabeth Oropesa.
He won his first award in 1977 Metro Manila Film Festival as Best Child Performer from the movie Ang Lalake, Ang Alamat at ang Baril with actor Fernando Poe Jr. He has received three more trophies for the movies Tatak ng Tondo (1978), Ang Lihim ng Guadalupe (1979), Hoy Tukso Layuan Mo Ako (1980), with awards in 1978 as MMFF-Best Child Performer and two awards from FAMAS as Best Child Actor, respectively.

## Personal life

Louie was a graduate of Far Eastern University, BSC Major in Management. He married at the age of 20 to Joni Peralta, became the father of two children, and then separated after three years. He was in a relationship with Teresa. They had one child together.
Bentot Jr. was an active member of the born-again Christian movement, where he was tasked with the evangelist integration for jail ministry, and was working as an agent servicing for Energy Supplier Company, an outsourcing industry company.

## Death

Bentot Jr. died on May 5, 2016, in Manila, Philippines at the age of 46.

## Filmography

* 1973 - Tama Na, Erap
* 1974 - Darna vs. the Planet Women – Ding
* 1975 - Mark of the Dragon
* 1976 - The Return of the Dragon (1st International movie)
* 1977 - Ang Lalake, Ang Alamat at ang Baril (MMFF Awardee)
* 1978 - Super Text
* 1978 - Tatak ng Tondo (MMFF Awardee)
* 1979 - Ang Lihim ng Guadalupe (FAMAS Awardee)
* 1980 - Hoy Tukso Layuan Mo Ako (FAMAS Awardee)
* 1980 - Ang Panday
* 1981 - Pagbabalik ng Panday
* 1982 - Johnny Tanggo Rides Again... Tatanga-tanga, Dakila Naman
* 1982 - Ang Panday: Ikatlong Yugto
* 1984 - Ang Panday IV: Ika-Apat Na Aklat
* 1985 - Campus Beat
* 2000 - Most Wanted
* 2001 - Twosong Twosome
* 2002 - Home Along the River
* 2011 - Dyagwar
# Martine Janssen

Martine Stephanie Janssen (born 16 June 1977 in Dieren, Gelderland) is a former breaststroke swimmer from the Netherlands, who competed for her native country at the 1992 Summer Olympics in Barcelona, Spain. There she was eliminated in the heats of the 100m and 200m Breaststroke.
# PP-131 Jhang-VII

PP-131 Jhang-VII (پی پی-131، جھنگ-7) is a constituency of the Provincial Assembly of Punjab, Pakistan.

## General elections 2024

Provincial election 2024: PP-131 Jhang-VII :
| Party | Party | Candidate | Votes | % | ±% |
| | Independent | Mian Muhammad Azam | 73,239 | 49.43 | |
| | PML(N) | Faisal Hayat | 59,578 | 40.21 | |
| | TLP | Ahsan Ullah | 6,995 | 4.72 | |
| | PPP | Syed Maratab Ali Shah | 2,165 | 1.46 | |
| | Others | Others (sixteen candidates) | 6,191 | 4.18 | |
| Turnout | Turnout | Turnout | 152,581 | 60.96 | |
| Total valid votes | Total valid votes | Total valid votes | 148,168 | 97.11 | |
| Rejected ballots | Rejected ballots | Rejected ballots | 4,413 | 2.89 | |
| Majority | Majority | Majority | 13,661 | 9.22 | |
| Registered electors | Registered electors | Registered electors | 250,311 | | |
| | hold | hold | hold | hold | hold |

## General elections 2018

Provincial election 2018: PP-125 Jhang-II :
| Party | Party | Candidate | Votes | % |
| | Independent | Faisal Hayat | 51,050 | 42.47 |
| | PTI | Mian Muhammad Azam | 38,699 | 32.19 |
| | Independent | Muhammad Javaid Akbar | 12,162 | 10.12 |
| | Independent | Iqbal Anmad Khan | 8,315 | 6.92 |
| | TLP | Umar Hayat | 4,048 | 3.37 |
| | MMA | Ch. Sajid Ali Chadhar | 3,779 | 3.14 |
| | Independent | Fakhar Abbas | 1,524 | 1.27 |
| | Others | Others (four candidates) | 628 | 0.53 |
| Turnout | Turnout | Turnout | 125,885 | 63.54 |
| Total valid votes | Total valid votes | Total valid votes | 120,205 | 95.49 |
| Rejected ballots | Rejected ballots | Rejected ballots | 5,680 | 4.51 |
| Majority | Majority | Majority | 12,351 | 10.28 |
| Registered electors | Registered electors | Registered electors | 198,117 | |

## General elections 2013

| Contesting Candidates | Party Affiliation | Votes Polled |

## General elections 2008

| Contesting Candidates | Party Affiliation | Votes Polled |