# List of county roads in Lafayette County, Florida

The following is a list of county roads in Lafayette County, Florida. All county roads are maintained by the county in which they reside, although not all routes are marked with standard county road shields.

## County roads in Lafayette County

| Route | Road Name(s) | From | To | Notes |
| CR 53 | | US 27 (SR 20) / CR 534 in Buckville | CR 53 at the Madison County line north-northeast of Day | Former SR 53 |
| CR 138A | | CR 490 north-northeast of Hatchbend | Riverside Drive north-northeast of Hatchbend | Unsigned |
| CR 250 | | CR 53 north-northeast of Day | CR 250 at the Suwannee County line north-northeast of Day | Former SR 250 |
| CR 251 | | US 27 (SR 20) / CR 350 southeast of Buckville | CR 250 north-northeast of Day | Former SR 251 |
| CR 260 | | CR 53 north-northeast of Day | CR 251 northeast of Day | Former SR 348C |
| CR 270 | | CR 53 / NW Maine Avenue in Day | CR 251 east of Day | Former SR 348B |
| CR 280 | | CR 53 / NW Gulfwind Avenue south of Day | CR 251 southeast of Day | |
| CR 290 | | CR 53 south of Day | CR 292 / Ezell Landing Road at Allen Mill Pond Conservation Area southeast of Day | Former SR 348A |
| CR 292 | | US 27 (SR 20) southeast of Buckville | CR 290 / Ezell Landing Road at Allen Mill Pond Conservation Area southeast of Day | Former SR 251B |
| CR 300 | | CR 534 northwest of Mayo | US 27 (SR 20) / NW Bloxham Street in Mayo | Unsigned except on street signs; former SR 251 (north of CR 320) and SR 251A (south of CR 320) |
| CR 320 | | CR 300 west-northwest of Mayo | US 27 (SR 20) northwest of Mayo | Former SR 251 |
| CR 340 | | CR 355 south-southeast of Mayo | Shaw Road / Parker Avenue east-southeast of Mayo | former SR 251 |
| CR 348 | | US 27 (SR 20) west of Buckville | CR 53 north-northeast of Buckville | Former SR 348 |
| CR 350 | | CR 534 / SW Arlington Road south of Buckville | US 27 (SR 20) / CR 251 southeast of Buckville | Former SR 350 |
| CR 351 | | CR 534 south-southeast of Buckville | CR 350 / SW Dickens Road southeast of Buckville | Former SR 350 |
| CR 353 | | US 27 (SR 20) / W.R. Williams Road east of Alton | CR 354 north-northeast of Alton | |
| CR 354 | | SR 51 / Savannah Road north of Mayo | US 27 (SR 20) / CR 405 east of Alton | Former SR 354 |
| CR 355 | Pine Street | CR 360 south-southeast of Mayo | SR 51 / Pine Street in Mayo | Former SR 355 |
| CR 357 | | CR 357 at the Dixie County line south-southeast of Cooks Hammock | SR 51 in Cooks Hammock | former SR 357 |
| CR 360 | | SR 51 south-southwest of Mayo | CR 405 south of Midway | Former SR 355 (east of CR 355) and SR 355A (west of CR 355) |
| CR 361 | | US 27 (SR 20) / CR 371 east of Alton | CR 354 / NE Pecan Avenue northeast of Alton | |
| CR 371 | | SE Knox Lake Road southeast of Alton | US 27 (SR 20) / CR 361 east of Alton | |
| CR 400 | | SR 51 north of Mayo | US 27 (SR 20) east of Mayo | |
| CR 405 | | US 27 (SR 20) west-northwest of Grady | US 27 (SR 20) / CR 354 east of Alton | Former SR 354 |
| CR 410 | | US 27 (SR 20) / Walter Henderson Road east-southeast of Alton | Owen Springs Boat Ramp on the Suwannee River east-southeast of Alton | Former SR 251 (east of CR 411) |
| CR 411 | | US 27 (SR 20) southeast of Alton | CR 410 east-southeast of Alton | Former SR 251 |
| CR 412 | | US 27 (SR 20 southeast of Alton | US 27 (SR 20 east-southeast of Alton | Former SR 251 |
| CR 416 | | CR 405 southeast of Alton | US 27 (SR 20) east-southeast of Alton | Former SR 354A |
| CR 420 | | CR 405 west-northwest of Grady | US 27 (SR 20) / Mandarin Road west-northwest of Grady | |
| CR 425 | | US 27 (SR 20) northwest of Grady | Orchid Road / Jeff Walker Road west-northwest of Grady | |
| CR 450 | | US 27 (SR 20) | Mandarin Road / Lavender Road / C-420 | |
| CR 475 | | US 27 (SR 20) west-northwest of Grady | SR 349 west-southwest of Grady | |
| CR 480 | | SR 349 | Boat Ramp along the Suwannee River | Former SR 138 (east of CR 500) and SR 342 (west of CR 500) |
| CR 500 | | SR 349 west of Hatchbend | CR 480 north-northwest of Hatchbend | Former SR 342 |
| CR 534 | | US 27 (SR 20) / CR 53 | SR 51 / CR 536 / NE Suwannee Acres Lane north of Mayo | Former SR 53 |
| CR 536 | | US 27 (SR 20) northwest of Mayo | SR 51 / CR 534 / NE Suwannee Acres Lane north of Mayo | Former SR 53 |