# List of Billboard number-one dance singles of 2001

These are the Billboard Hot Dance/Disco Club Play and Maxi-Singles Sales number-one hits of 2001.
| Issue date | Club Play Song | Artist | Maxi-Singles Sales | Artist |
| January 6 | "One More Time" | Daft Punk | "Independent Women Part I" | Destiny's Child |
| January 13 | "The Underground" | Celeda | "Independent Women Part I" | Destiny's Child |
| January 20 | "Don't Tell Me" | Madonna | "Independent Women Part I" | Destiny's Child |
| January 27 | "Lady (Hear Me Tonight)" | Modjo | "Independent Women Part I" | Destiny's Child |
| February 3 | "Beautiful Day" | U2 | "Don't Tell Me" | Madonna |
| February 10 | "Lovin' You" | Kristine W | "Don't Tell Me" | Madonna |
| February 17 | "Boy" | Book of Love | "Don't Tell Me" | Madonna |
| February 24 | "Papa's Got a Brand New Pigbag" | Thunderpuss | "Don't Tell Me" | Madonna |
| March 3 | "Stranger in My House" | Tamia | "Don't Tell Me" | Madonna |
| March 10 | "Who the Hell Are You" | Madison Avenue | "Butterfly" | Crazy Town |
| March 17 | "Needin' U II" | David Morales presents The Face featuring Juliet Roberts | "Love Don't Cost A Thing" | Jennifer Lopez |
| March 24 | "Just Keep Thinking About You" | Gloria Gaynor | "Love Don't Cost A Thing" | Jennifer Lopez |
| March 31 | "The Power" | Rosabel featuring Jeanie Tracy | "Love Don't Cost A Thing" | Jennifer Lopez |
| April 7 | "Mine to Give" | Photek featuring Robert Owens | "Love Don't Cost A Thing" | Jennifer Lopez |
| April 14 | "Is It Love?" | Chili Hi Fly | "Stranger In My House" (Remixes) | Tamia |
| April 21 | "Looking for Love" | Karen Ramirez | "Stranger In My House" (Remixes) | Tamia |
| April 28 | "Are You Satisfied" | Victor Calderone featuring Deborah Cooper | "Stranger In My House" (Remixes) | Tamia |
| May 5 | "Are You Satisfied" | Victor Calderone featuring Deborah Cooper | "Stranger In My House" (Remixes) | Tamia |
| May 12 | "All for You" | Janet | "Dream On" | Depeche Mode |
| May 19 | "All for You" | Janet | "What It Feels Like for a Girl" | Madonna |
| May 26 | "All for You" | Janet | "Survivor" (Remixes) | Destiny's Child |
| June 2 | "What It Feels Like for a Girl" | Madonna | "Survivor" (Remixes) | Destiny's Child |
| June 9 | "Dream On" | Depeche Mode | "Survivor" (Remixes) | Destiny's Child |
| June 16 | "Get It Up (The Feeling)" | Ultra Naté | "Survivor" (Remixes) | Destiny's Child |
| June 23 | "Get It Up (The Feeling)" | Ultra Naté | "Survivor" (Remixes) | Destiny's Child |
| June 30 | "You're the Worst Thing for Me" | Pusaka featuring Thea Austin | "Survivor" (Remixes) | Destiny's Child |
| July 7 | "Bumpin' and Jumpin'" | Kim English | "Survivor" (Remixes) | Destiny's Child |
| July 14 | "Keep Control" | Sono | "Survivor" (Remixes) | Destiny's Child |
| July 21 | "Keep Control" | Sono | "All Or Nothing" (Remixes) | O-Town |
| July 28 | "Keep Control" | Sono | "All Or Nothing" (Remixes) | O-Town |
| August 4 | "Keep Control" | Sono | "All Or Nothing" (Remixes) | O-Town |
| August 11 | "Planets of the Universe" | Stevie Nicks | "All Or Nothing" (Remixes) | O-Town |
| August 18 | "Someone to Call My Lover" | Janet | "All Or Nothing" (Remixes) | O-Town |
| August 25 | "You Set Me Free" | Abigail | "All Or Nothing" (Remixes) | O-Town |
| September 1 | "Thank You" | Dido | "All Or Nothing" (Remixes) | O-Town |
| September 8 | "I Feel Loved" | Depeche Mode | "All Or Nothing" (Remixes) | O-Town |
| September 15 | "I Feel Loved" | Depeche Mode | "Where the Party At" (Remixes) | Jagged Edge With Nelly |
| September 22 | "Absolutely Not" | Deborah Cox | "Where the Party At" (Remixes) | Jagged Edge With Nelly |
| September 29 | "Absolutely Not" | Deborah Cox | "Where the Party At" (Remixes) | Jagged Edge With Nelly |
| October 6 | "Stand Still" | Aubrey | "Where the Party At" (Remixes) | Jagged Edge With Nelly |
| October 13 | "Feel This 2001" | Robbie Rivera | "Where the Party At" (Remixes) | Jagged Edge With Nelly |
| October 20 | "Crystal" | New Order | "Where the Party At" (Remixes) | Jagged Edge With Nelly |
| October 27 | "Yes!" | Amber | "Where the Party At" (Remixes) | Jagged Edge With Nelly |
| November 3 | "It Began in Afrika" | The Chemical Brothers | "Where the Party At" (Remixes) | Jagged Edge With Nelly |
| November 10 | "Break 4 Love" | Peter Rauhofer + Pet Shop Boys = The Collaboration | "Lifetime" (Ben Watt Remix) | Maxwell |
| November 17 | "Impressive Instant" | Madonna | "Lifetime" (Ben Watt Remix) | Maxwell |
| November 24 | "Impressive Instant" | Madonna | "Lifetime" (Ben Watt Remix) | Maxwell |
| December 1 | "So Strong" | Ben Shaw featuring Adele Holness | "Lifetime" (Ben Watt Remix) | Maxwell |
| December 8 | "Lettin' Ya Mind Go" | Desert | "Lifetime" (Ben Watt Remix) | Maxwell |
| December 15 | "Hero" | Enrique Iglesias | "Lifetime" (Ben Watt Remix) | Maxwell |
| December 22 | "Turn Off the Light" | Nelly Furtado | "Trust Your Love" | Koda |
| December 29 | "Come on Down" | Crystal Waters | "Freelove" | Depeche Mode |