OpenLLM-France/wikimedia huggingface dataset:
# Ro65-6570

Ro65-6570 is an opioid drug. It has a potential use in preventing the addiction to other opioids.

## Mechanism of action

Ro65-6570 is an opioid drug, it works by activating opioid receptors. However, instead of acting at the mu, kappa and delta receptors, it is instead an agonist at the nociceptin receptor.

## Potential uses
### Analgesic

Ro65-6570 has analgesic properties. In rats, it is able to reduce cancer pain. It is also able to reduce pain caused by arthritis.

### Prevention of opioid addiction

While being an opioid agonist, Ro65-6570 did not display addictive properties, it instead reduced the addictive properties of other opioids, but did not affect the analgesic effect of those. This could make it useful if combined with more potent opioids, for example oxycodone and Ro65-6570 would reduce pain, but would be less addictive, unlike oxycodone alone. This effect was antagonized by the nociceptin receptor antagonist J-113,397, further suggesting that this action is linked to the NOP receptor.
# Superfrank!

Superfrank! is a 1987 one-hour television special starring English comedian Frankie Howerd OBE. The special show marked his return to television performance after an absence of five years.
The show was made by Channel 4 and HTV. The script was written by Miles Tredinnick, Vince Powell and Andrew Nickolds and recorded before a live audience at the Playhouse Theatre in Weston-super-Mare close to where Howerd had his country home in the Mendips. At one stage he is joined by some donkeys who do their best to upstage him. Howerd ends the show with some songs accompanied on the piano by Sunny Rogers. The show was produced by Cecil Korer and Derek Clark. It was transmitted in January 1987.
The show's working title was 'Let's Be Frank!'

## DVD release

Superfrank! is available on DVD as part of the two-disc Network DVD release Oh, Please Yourselves - Frankie Howerd at ITV.
# Ekaterina Avramova (swimmer)

Ekaterina Avramova (Bulgarian: Екатерина Аврамова; born 12 November 1991, in Sofia) is a Bulgarian-born swimmer competing for Turkey.

## Career

She learned how to swim at age 7 and her first coach was Jorj Stankovich. Her mother had represented Bulgaria in water polo. Avramova started her professional swimming career in 2007 representing Bulgaria at the European Short Course championship in Debrecen (Hungary). From that year until end of 2013 she represented Bulgaria in every major international competition. She broke the national backstroke records more than 70 times, both LC and SC.
In 2009, she moved from Bulgaria, to live and continue her training in London, U.K. as part of Ealing Swimming Club with Head Coach David Heathcock. Avramova qualified for the London Olympic Games in 2012 on both 100m and 200m backstroke.
After Bulgaria cut off funding for her following the 2012 Summer Olympics, she decided in August 2014 to move to Turkey accepting Turkish citizenship, and competing for Turkey.
Avramova was semi-finalist in the 2011 World Long Course Championship; Finalist in 50m,100m and 200m at the European Short Course Championship in 2011;2016 European Championships finalist in 50m and 100m backstroke and 200m back semi-finalist, 5 timed gold medalist at the Islamic Games in Baku 2017; 2 times bronze medalist at the Mediterranean Games in 2018; 2018 European Championships semi-finalist in 200m backstroke, and World Championship finalist in the 4×100 m freestyle relay. She has competed at two Olympics, competing at London 2012 for Bulgaria and at Rio 2016 for Turkey.
Ekaterina Avramova is the current Turkish and Bulgarian National Record holder in all backstroke events both long and short course. She is a member of ENKA Spor Kulubu since 2018, as prior to that she competed for Galatasaray and Fenerbahce.
As of December 2022, she is the Turkish record holder in the 100 and 200 m backstroke shortcourse, and the 50 m backstroke long course (she is also still the Bulgarian record holder in the 200 m backstroke long course), and was part of the teams that hold the national record in the women's 4 x 50 m medley relay and mixed 4 x 50 m freestyle relay (shortcourse) and mixed 4 x 100 m freestyle and 4 x 100 m medley relays (long course).
# Exeter crossing loop collision

The Exeter crossing loop collision was a railway accident that occurred between the Temora Mail Train and a goods train at Exeter railway station, New South Wales, on 13 March 1914. At that time the main line was a single track, with a crossing loop and a down refuge siding at Exeter.

## Events leading to accident

The up fast goods train was running late by the time it reached Exeter. Despite the train's being too long to be accommodated in the loop at that station, the signaller [night officer] turned the train into the loop. When the locomotive had reached the points at the Sydney end of the station, the rear of the train was still on the main line at the southern end.
Faced with the knowledge that the Temora Mail would soon be due, the goods train was brought forward so that it could be reversed into a siding on the eastern side of the station yard. It was during this manoeuvre that the Temora Mail struck the goods train head-on.

## Court trial for manslaughter

Questions were swiftly raised as to why two trains should collide when the goods train should have had the protection of the home signal. The mail train driver claimed that the distant signal was clear when he passed it; however, as there was a thick fog at the time, he did not sight the home signal, which was against him, until the train was right upon it.
The driver of the mail train was brought before the Goulburn Circuit Court charged with manslaughter. At that trial, the night officer at Exeter gave evidence to the effect that the down distant signal was in fact at danger at the time the mail train passed. The night officer further stated that there was no fog that night, but that just before the goods train arrived a slight mist had set in. However, the goods train driver gave conflicting evidence, stating that on the night of the accident the denseness of the fog made it difficult to see the signals.
After a retirement of more than four hours, the jury delivered a verdict of "not guilty."

## Deceased

The collision killed 14. Five were said to have been killed almost instantly, three died while still crushed in their carriages, one succumbed as rescuers reached him, and two died on the Exeter station platform. The remaining three reportedly died in a temporary hospital that had been set up in a sleeping carriage. Alfred Bray, the guard, was one of those killed in the collision.
# Peebles High School (Ohio)

Peebles High School is a public high school located in Peebles, Ohio. It is one of three high schools in the Adams County/Ohio Valley School District. The other county schools are North Adams and West Union. The district also has a vocational school (Ohio Valley Career and Technical Center).

## History of Peebles High School

Peebles High School was established in 1887. Peebles, Franklin, and Sinking Spring school districts were consolidated in 1968 and became a part of the Ohio Valley Local School District in 1970. In the history of Peebles High School four buildings have served the high school:
In 1887 a two-room, two-story wooden school building was erected near the intersection of Vine St. and Wendell Ave. and served as the first Peebles High School. A. C. Hood was the first superintendent and 75 pupils were enrolled. The first class of four (Florence Custer Nixon, Anna Platter Watts, D. W. Reynolds, and Grace Wickerham) graduated in 1891. There was no graduation in the following years: 1892, 1893, 1895, 1896, 1899, 1900, 1901, 1902, 1903, 1906, 1907, and 1908. This building was destroyed by a fire around 1910. Following that fire, a large red brick building was completed in 1913 at a cost of $24,000 and served first as the high school, then later as the elementary school. This building had 6 class rooms, an auditorium, small library, typing room, and office. Band, home economics, and agriculture were later added to the curriculum. The wooden-frame "old gym" was erected nearby in 1927. This building was raised in (year needed) Because of the rapidly expanding population, a new high school building, located on Simmons Avenue, was completed in 1952. This was built of yellow brick. A major addition was completed in February 1958 adding several classrooms to the West end of the main building. A single-story addition with four classrooms and two restrooms was added to the east end in 1974-75. In the early 1990s, a new Vo. Ag. classroom was added along with an elevator. In its last years as a high school, there were 28 classrooms, library, Vo. Ag. classroom and shop, industrial arts classroom and shop, home economics classroom and kitchen, art room, computer lab and gymnasium. At that time the building housed 550 students in grades 7-12. This building became an elementary school from 1997-2010, and was raised in August 2011. The present Jr/Sr high school building was completed in 1997.

## Controversy

The four regular public high schools in Adams County were built at the same time and all four featured a large granite tablet outside the school carved with the Ten Commandments. They were relocated after a lengthy four-year legal battle over the placement of the tablets on public property. In Peebles, the tablet now is located directly across the street facing the high school on the property of the Peebles Baptist Church.
* Ten Commandments tablet.
* Ten Commandments tablet.

## Athletics

All Peebles teams are nicknamed "The Indians," because of the town's close proximity to Serpent Mound.
The school has Jr. high and high school sports in soccer, cross country, golf, volleyball, baseball and basketball.
# Ngconde Balfour

Ngconde Mathemba Bryce Balfour (born 23 August 1954 in kuNtselamanzi, Alice, Eastern Cape) is a South African politician and has served as Minister of Correctional Services and Minister of Sport.

## Early life and career

Balfour was born in the Eastern Cape and completed his schooling at Jabavu High School in the town of Alice. He went on to study at Lovedale College and Fort Hare University. After spending time as a political detainee, Balfour went into exile in Australia from 1989 to 1992. While in Australia, he attended Victoria University, Australia.
Balfour has been a South African Member of Parliament since 1996 and was appointed as Minister of Correctional Services on 29 April 2004.
Following the resignation of President Thabo Mbeki in September 2008, Balfour was one of ten ministers who submitted their resignations on 23 September, although it was subsequently announced that he might be willing to remain in his post. He was retained in his post as the Cabinet announced on 25 September.
Balfour was appointed as South Africa's high commissioner to Botswana but resigned the position less than a year after the diplomatic posting.
In 2011 it was announced that Balfour was taking over as the chairperson of Boxing South Africa.

## Woodhill Golf Estate

Balfour's wife Thozama Mqobi-Balfour, Correctional Services regional commissioner for Gauteng, was suspended pending the outcome of a disciplinary process for renting a house in the Woodhill Golf Estate in Pretoria for some R30,000 a month despite having the use of an official residence. She was also named by Auditor-General Terence Nombembe as one of 49 government officials who benefited from government contracts worth R74m. Fellow National commissioner Xoliswa Sibeko was also suspended for renting a home in the same golf estate for R35,000 a month.
# George W. Jack

George Whitfield Jack (November 1, 1875 – March 15, 1924) was a United States district judge of the United States District Court for the Western District of Louisiana.
Jack was nominated by President Woodrow Wilson on March 6, 1917, to a seat vacated by Alexander Boarman. He was confirmed by the United States Senate on March 16, 1917, and received commission the same day. Jack's service was terminated on March 15, 1924, due to death.

## Education and career

Born on November 1, 1875, in Natchitoches, Louisiana, Jack received a Bachelor of Laws in 1898 from Tulane University Law School. He entered private practice in Shreveport, Louisiana from 1898 to 1910. He was the city attorney for Shreveport from 1910 to 1913. He was the United States Attorney for the Western District of Louisiana from 1913 to 1917.

## Federal judicial service

Jack was nominated by President Woodrow Wilson on March 6, 1917, to a seat on the United States District Court for the Western District of Louisiana vacated by Judge Alexander Boarman. He was confirmed by the United States Senate on March 16, 1917, and received his commission the same day. His service terminated on March 15, 1924, due to his death in Shreveport.
# James Halpern

James S. Halpern (born October 16, 1945, in Brooklyn, New York) is an American lawyer who serves as a senior judge of the United States Tax Court.
Halpern attended Hackley School in Tarrytown, New York until 1963 and earned a B.S. at the Wharton School of the University of Pennsylvania in 1967. He received a Juris Doctor from the University of Pennsylvania Law School in 1972, followed by a Master of Laws in taxation from New York University Law School in 1975, earned while he worked as an associate in the law firm of Mudge, Rose, Guthrie and Alexander in New York City.
He taught law at Washington and Lee University and St. John's University, and New York University until 1979, then briefly returned to private practice with Roberts and Holland in New York City before joining the legal staff of the Internal Revenue Service from 1980 to 1983.
He was a partner with Baker Hostetler in Washington, D.C. from 1983 to 1990, while also teaching on a limited basis at George Washington University.
Halpern was appointed by President George H. W. Bush as Judge, United States Tax Court, on July 3, 1990, for a term ending July 2, 2005, and re-appointed by George W. Bush on November 2, 2005, for a term ending November 1, 2020. He retired on October 16, 2015, but continues to perform judicial duties as senior judge on recall.
Halpern is married to former Consumer Product Safety Commission acting Chairwoman, Nancy Nord. He has a son and daughter.

## Other

* Colonel, U.S. Army Reserve (retired).
# Boreen

A boreen or bohereen (/bɔːˈriːn/ bor-EEN; Irish: bóithrín, meaning 'a little road') is a country lane, or narrow, frequently unpaved, rural road in Ireland.
"Boreen" also appears sometimes in names of minor urban roads such as Saint Mobhi Bóithrín (Irish: Bóithrín Mobhí), commonly known as Mobhi Boreen in Glasnevin, Dublin. To be considered a boreen the road or path should not be wide enough for two cars to pass and have grass growing in the middle.
Boreens may be private rights of way that are not open for public use.
In parts of Ulster, a boreen is often called a loanin, an Ulster Scots word.

## Etymology

The word "boreen" comes from the Irish word bóithrín ("little road"), which in turn comes from bóthar ("road").
In origin, a bóthar was a cow path (bó means cow), a track the width of two cows, so bóithrín meant a little cow path. Bóthar was one of the five types of road identified in medieval Irish legal texts, the others being slige (on which two chariots could pass), rót (on which one chariot and two riders could pass), lámraite (a road connecting two major roads) and tógraite (a road leading to a forest or a river).
# DayQuil

Vicks DayQuil is an over-the-counter combination medication product used for the temporary relief of common cold and flu symptoms. DayQuil is available in several formulations.
DayQuil was introduced in 1974 under the name "Vicks DayCare" and is currently advertised for daytime use because of its non-drowsy active ingredients. The brand name was reintroduced as " DayQuil" in 1992. DayQuil's nighttime counterpart, NyQuil, is also available for the relief of cold and flu symptoms during the night. These products are not intended to cure the common cold or the flu.

## Product selection

Selecting a product should depend on the specific symptom presentation of the user. Products should be selected with active ingredients limited only to those symptoms, thereby reducing the risk of over treatment with medications that the user is not showing symptoms for. Additionally, careful note should be taken when purchasing multiple over-the-counter cold and flu medicines because many products may contain the same active ingredient. The potential for overdose increases when consumers are unaware of the duplication of active ingredients in these medicines.

## Research

There are conflicting studies showing the effectiveness of over-the-counter cold medicine in reducing cold and flu symptoms. A number of studies have found acetaminophen (alone and in combination) to be effective and a safe treatment for common cold symptoms such as sore throat and body aches. In contrast, a systematic review including 26 randomized controlled trials compared the use of over-the-counter cough medicines with no treatment in children and adults exhibiting cough in the ambulatory or outpatient setting. Among the studies, there was conflicting evidence of the effectiveness of cough medicines containing an antitussive, antihistamine or decongestant in providing better cough resolution outcomes versus no treatment.

## Social and culture
### Recreational use

Abuse and recreational use of dextromethorphan have been reported with over-the-counter preparations and can cause euphoric and dissociative effects at higher than recommended doses.

## Warnings
### Products containing acetaminophen

There is a risk of severe liver damage with the concurrent use of acetaminophen products and excessive alcohol use (≥3 alcoholic drinks/day depending on body weight). Acetaminophen is an active ingredient of many over-the-counter single ingredient products (e.g. to treat headache), multiple ingredient combination products as well as prescription-only medications written by a physician. Each formulation also varies per dose. When purchasing over-the-counter medications, avoid purchasing multiple products with acetaminophen ingredients. The suggested maximum daily intake of acetaminophen is limited to <4 grams (4,000 mg) daily in adults or <2.6g (2,600 mg) daily in children <12 years of age to reduce the risk of liver damage.

### Products containing dextromethorphan

Those prescribed monoamine oxidase inhibitor (MAO-i) should avoid the use of DayQuil products containing dextromethorphan within 2 weeks to avoid risks of Serotonin Syndrome.
# Edward Coke Billings

Edward Coke Billings (December 3, 1829 – December 1, 1893) was a United States district judge of the United States District Court for the District of Louisiana and the United States District Court for the Eastern District of Louisiana.

## Education and career

Born on December 3, 1829, in Hatfield, Massachusetts, Billings graduated from Yale University in 1853 and received a Bachelor of Laws from Harvard Law School in 1855. He entered private practice in New York City, New York from 1855 to 1865. He continued private practice in New Orleans, Louisiana from 1865 to 1876.

## Federal judicial service

Billings was nominated by President Ulysses S. Grant on January 10, 1876, to a seat on the United States District Court for the District of Louisiana vacated by Judge Edward Henry Durell. He was confirmed by the United States Senate on February 10, 1876, and received his commission the same day. Billings was reassigned by operation of law to the United States District Court for the Eastern District of Louisiana on March 3, 1881, to a new seat authorized by 21 Stat. 507. His service terminated on December 1, 1893, due to his death in New Haven, Connecticut.

## Unsuccessful nomination

Billings was nominated by President Rutherford B. Hayes to the United States Circuit Courts for the Fifth Circuit on January 24, 1881, but the Senate never voted on his nomination.
# Branimir Popov

Branimir Popov (Bulgarian: Бранимир Попов, born 10 May 1962) is a Bulgarian swimmer. He competed in two events at the 1980 Summer Olympics.
# 1915 Japanese general election

General elections were held in Japan on 25 March 1915. The Rikken Dōshikai party emerged as the largest party in the House of Representatives, winning 153 of the 381 seats.

## Electoral system

The 381 members of the House of Representatives were elected in 51 multi-member constituencies based on prefectures and cities. Voting was restricted to men aged over 25 who paid at least 10 yen a year in direct taxation.

## Results

| | Rikken Dōshikai | 523,228 | 36.92 | 153 | New |
| | Rikken Seiyūkai | 446,934 | 31.54 | 108 | –101 |
| | Rikken Kokumintō | 106,445 | 7.51 | 27 | –68 |
| | Chūseikai | 101,970 | 7.20 | 33 | New |
| | Okuma Kōenkai | 55,684 | 3.93 | 12 | New |
| | Others | 182,814 | 12.90 | 48 | +2 |
| Total | Total | 1,417,075 | 100.00 | 381 | 0 |
| Valid votes | Valid votes | 1,417,075 | 99.47 | | |
| Invalid/blank votes | Invalid/blank votes | 7,570 | 0.53 | | |
| Total votes | Total votes | 1,424,645 | 100.00 | | |
| Registered voters/turnout | Registered voters/turnout | 1,546,411 | 92.13 | | |
| Source: Mackie & Rose, Statistics Bureau of Japan ||||||
# N'Guelbély

N'Guelbély (also: Nguel Bely, N'Guelbeyli, N'Guel Beyli) is a village and rural commune in Niger.

## Geography

N'Guelbély lies in the Sahel. The neighboring communes are Tesker to the north, N'Gourti to the northeast, Foulatari to the east, south and Maïné-Soroa Goudoumaria are in the southwest. The commune is divided into the administrative village of N'Guelbély, five camps and two water sources. The seat of the community is the administrative village of N'Guelbély.

## History

The rural community of N'Guelbély emerged as an administrative unit in 2002 as part of a nationwide administrative reform, dividing the territory of the canton of Maïné-Soroa, creating the communities of Foulatari, Maïné-Soroa and N'Guelbély.
In the 2001 census, N'Guelbély had 1,000 inhabitants. For the year 2012, 21,976 inhabitants were reported.

## Economy and Infrastructure

The community is located in the transition zone to the south of the Agropastoralismus zone of pure pasture economy in the north.
# Michael Henry Sheridan

Michael Henry Sheridan (July 8, 1912 – August 23, 1976) was a United States district judge of the United States District Court for the Middle District of Pennsylvania.

## Education and career

Sheridan was born in Nanticoke, Pennsylvania, Sheridan received a Bachelor of Science degree from Lafayette College in 1933. He received a Bachelor of Laws from Dickinson School of Law (now Penn State Dickinson Law) in 1936. He entered private practice from 1937 to 1942. He was in the United States Navy from 1942 to 1947. He was an Assistant United States Attorney of the District of Columbia in Washington, D.C. in 1947. He returned to private practice from 1948 to 1961.

## Federal judicial service

Sheridan was nominated by President John F. Kennedy on August 15, 1961, to the United States District Court for the Middle District of Pennsylvania, to a new seat created by 75 Stat. 80. He was confirmed by the United States Senate on August 30, 1961, and received his commission the same day. He served as Chief Judge from 1962 to 1976. and as a member of the Judicial Conference of the United States from 1972 to 1975. His service was terminated on August 23, 1976, due to his death at his residence at the Westmoreland Club in Wilkes-Barre, Pennsylvania.