# List of chemical process simulators

This is a list of software used to simulate the material and energy balances of chemical process plants. Applications for this include design studies, engineering studies, design audits, debottlenecking studies, control system check-out, process simulation, dynamic simulation, operator training simulators, pipeline management systems, production management systems, digital twins.
| Software | Developer | Applications | Operating System | License | URL |
| Advanced Simulation Library (ASL) | Avtech Scientific | Process data validation and reconciliation, real-time optimization, virtual sensing and predictive control | Windows, Linux, FreeBSD, Mac | open-source (AGPLv3) | |
| APMonitor | APMonitor | MATLAB/Python/Julia-based data reconciliation, real-time optimization, dynamic simulation and nonlinear predictive control | Windows, Linux | open-source (BSD-2-Clause) | |
| Apros | Fortum and VTT Technical Research Centre of Finland | Dynamic process simulation for power plants | Windows | closed-source | |
| ASCEND | ASCEND | Dynamic process simulation, general purpose language | Windows, BSD, Linux | open-source (GPLv2) | |
| Aspen Custom Modeler (ACM) | Aspen Technology | Dynamic process simulation | Windows | closed-source | |
| Aspen HYSYS | Aspen Technology | Process simulation and optimization | Windows | closed-source | |
| Aspen Plus | Aspen Technology | Process simulation and optimization | Windows | closed-source | |
| ASSETT | Kongsberg Digital | Dynamic process simulation | Windows | closed-source | |
| BatchColumn | Fives ProSim | Simulation and Optimization of batch distillation columns | Windows | closed-source | |
| BATCHES | Batch Process Technologies, Inc. | Simulation of recipe driven multiproduct and multipurpose batch processes for applications in design, scheduling and supply chain management | Linux | closed-source | |
| BatchReactor | Fives ProSim | Simulation of reactors in batch mode | Windows | closed-source | |
| BILCO | CASPEO | Software to simulate mass balances using a data reconciliation algorithm | Windows | closed-source | |
| BioSTEAM | Yoel Cortes-Pena & BioSTEAM Development Group | Design, simulation, and costing of biorefineries under uncertainty | Windows, Mac, Linux | open-source (BSD-3-Clause) | |
| CADSIM Plus | Aurel Systems Inc. | Dynamic process simulator with CAD front end and process stream specification flexibility | Windows | closed-source | |
| ChromWorks | YPSO-FACTO | Chromatographic process design, simulation & optimization | Windows | closed-source | |
| CHEMCAD | Chemstations | Software suite for process simulation | Windows | closed-source | |
| CHEMPRO | EPCON | Process Flow Simulation, Fluid Flow Simulation, & Process Equipment Sizing | Windows | closed-source | |
| Cycad Process | CM Solutions | Process simulation and drawing package for minerals and metallurgical fields | Windows | closed-source | |
| Cycle-Tempo | Asimptote | Thermodynamic analysis and optimization of systems for the production of electricity, heat and refrigeration | Windows | closed-source | |
| COCO simulator + ChemSep | AmsterCHEM | Steady state process simulation based on CAPE-OPEN Interface Standard | Windows | open-source (Coco License 3.4) | |
| D-SPICE | Kongsberg Digital | Dynamic process simulation | Windows | closed-source | |
| Design II for Windows | WinSim Inc. | Process simulation | Windows | closed-source | |
| Distillation expert trainer | ATR | Operator training simulator for distillation process | | closed-source | |
| Dymola | Dassault Systèmes | Modelica-based dynamic modelling and simulation software | Windows, Linux | closed-source | |
| DynoChem | Scale-up Systems | Dynamic process simulation and optimization | Windows | closed-source | |
| DYNSIM | AVEVA | Dynamic process simulation | Windows | closed-source | |
| Dyssol | DyssolTEC | Dynamic flowsheet simulation of solids processes | Windows, Linux | open-source (BSD-3-Clause) | |
| DWSIM | Daniel Medeiros, Gustavo León and Gregor Reichert | Process simulator | Windows, Linux, macOS, Android, iOS | open-source (GPLv3), freemium | |
| EMSO | ALSOC Project | Modelling, simulation and optimisation, steady state and dynamic, equation oriented with open source models | Windows, Linux | closed-source (UI), open-source (library) | |
| EQ-COMP | Amit Katyal | Vapor Liquid Equilibrium Software | Software-as-a-Service | closed-source | |
| FlowTran | FlowTran | Transient single phase pipeline simulation | | closed-source | |
| GAMS | GAMS | General Algebraic Modeling System (GAMS) | Windows, Linux, Mac OS, Solaris | closed-source | |
| gPROMS | PSE Ltd | Advanced process simulation and modelling | | closed-source | |
| HSC Sim | Outotec Oyj | Advanced process simulation and modelling, Flowsheet simulation | Windows | closed-source | |
| HYD-PREDIC | Amit Katyal | Multiphase flow assurance and hydrate modelling | Software-as-a-Service | closed-source | |
| HYDROFLO | Tahoe Design Software | Piping System Design with Steady State Analysis | Windows | closed-source | |
| Indiss Plus® | Corys | Dynamic process simulator for hydrocarbons, chemicals | Windows | closed-source | |
| ICAS | KT-Consortium | Integrated Computer-Aided System | Windows | closed-source | |
| IDEAS | Andritz Automation | Dynamic simulator for pulp, oil sands, potash, and hard rock mining | Windows | closed-source | |
| iiSE Simulator | iiSE company | Equation oriented chemical process simulator and optimizer | Windows, Linux | closed-source | |
| INOSIM | Inosim Software GmbH | Discrete-event dynamic simulation software for mixed batch-continuous processes in the chemical and pharmaceutical industry | Windows | closed-source | |
| INVIDES | Rheinmetall Electronics | Visual, dynamic Process Simulation framework for power plants, pipeline systems, upstream, midstream and downstream oil & gas plants, renewable energy plants and hydrogen plants | Windows | closed-source | [91] |
| IPSE GO | SimTech GmbH | Process simulation application that works in the browser, provides a visual flowsheet editor and supports online collaboration | Software-as-a-Service | closed-source | |
| IPSEpro | SimTech GmbH | Visual process simulation framework with ready-to-use model libraries for power systems, desalination, flue gas cleaning etc. and option to define own model libraries | Windows | closed-source | |
| ITHACA | Element Process | General purpose dynamic chemical process simulator | Windows | closed-source | |
| JADE | GSE Systems | Dynamic process simulation | Windows | closed-source | |
| JModelica.org | Modelon AB | Process simulation | Windows, Linux, macOS | closed-source | |
| K-Spice | Kongsberg Digital | Dynamic process simulation | Windows | closed-source | |
| LedaFlow | Kongsberg Digital | Transient multiphase pipeline simulation | Windows | closed-source | |
| LIBPF | simevo | C++ Library for process flowsheeting | Linux, Windows, macOS | closed-source | |
| METSIM | Metsim International | General-purpose dynamic and steady-state process simulation system | Windows | closed-source | |
| Modelon Impact | Modelon AB | General-purpose, multi-domain dynamic and steady-state process and system simulation system | Linux (SaaS, on-prem), Windows | closed-source | |
| Mimic Simulation Software | MYNAH Technologies | First-principles dynamic simulator built for software acceptance testing and operator training systems | Windows | closed-source | |
| Mobatec Modeller | Mobatec | Advanced Dynamic (Steady-State) Process Modelling Environment | Windows | closed-source | |
| NAPCON ProsDS | Neste Engineering Solutions Oy | Dynamic process simulation | Windows | closed-source | |
| OLGA | Schlumberger | Transient multiphase pipeline simulation | Windows | closed-source | |
| OLI Analyzer | OLI Systems, Inc. | Chemical phase equilibrium simulation featuring electrolytes | Windows | closed-source | |
| Omegaland | OMEGA Simulation | Dynamic process simulation | Windows | closed-source | |
| OptiRamp | Statistics & Control, Inc. | Real-time Process Simulation and Optimization, Multi variable Predictive Control | Windows | closed-source | |
| OpenModelica | Open-Source Modelica Consortium | General purpose simulation | Linux, macOS | open-source (OSMC-PL 1.2) | |
| PD-PLUS | Deerhaven Technical Software | Steady-State Modeling of Chemical, Petrochemical, and Refining Processes | Windows | closed-source | |
| PIPE-FLO Professional | Engineered Software Inc. | Piping System Simulation and Design | Windows | closed-source | |
| PIPEFLO | Schlumberger | Steady state multiphase flowline simulation | Windows | closed-source | |
| PIPESIM | Schlumberger | Steady state multiphase flowline simulation | Windows | closed-source | |
| PEL Suite | PEL Software | Steady state process simulation | Windows | closed-source | |
| Petro-SIM | KBC Advanced Technologies | Dynamic process simulation | Windows | closed-source | |
| PETROX | Petrobras | In-house steady state refining process simulator | Windows | closed-source | N/A |
| Power Plant Simulator & Designer | KED GmbH | Basic Engineering and Dynamic process simulation for power plants | Windows | closed-source | |
| Process Engineering ToolS (PETS) | Stratus Engineering, Inc. | Process Engineering Software | Windows | closed-source | |
| Process Studio | Stamicarbon | Simulation Suite for Modeling, Engineering & Training | Windows | closed-source | |
| Prode Properties | Prode Software | Thermodynamic Library, Properties of pure fluids and mixtures, Multi phase Equilibria + process simulation | Windows, Linux, Android | closed-source | |
| Prode Process Interface | Prode Software | Process simulation, optimization realtime control | Windows | closed-source | |
| ProMax | Bryan Research & Engineering | Process simulator capable of modeling oil & gas plants, refineries, and many chemical plants | Windows | closed-source | |
| ProPhyPlus | Fives ProSim | Thermodynamic calculation software | Windows | closed-source | |
| ProSec | Fives ProSim | Simulation of brazed plate fin heat exchangers | Windows | closed-source | |
| ProSim DAC | Fives ProSim | Dynamic adsorption column simulation | Windows | closed-source | |
| ProSim HEX | Fives ProSim | Heat Exchangers Simulation | Windows | closed-source | |
| ProSimPlus | Fives ProSim | Steady-state simulation and optimization of processes | Windows | closed-source | |
| ProSimulator | Sim Infosystems | Process and Power plant simulation | Windows | closed-source | |
| ProTreat / SulphurPro | Optimized Gas Treating | Steady state simulation of amine gas sweetening, glycol dehydration, modified Claus SRUs, tail gas clean-up, and post-combustion carbon capture processes | Windows | closed-source | |
| PRO/II | AVEVA | Steady state process simulation | Windows | closed-source | |
| Pyomo | Sandia and UC Davis | Steady state and dynamic process simulation | All Platforms | open-source | |
| ROMeo | AVEVA | Process optimization | Windows | closed-source | |
| Reaction Lab | Scale-up Systems | Chemist-oriented kinetic modeling and reaction optimization | Windows | closed-source | |
| RecoVR | VRTech | Industrial wastewater management | Windows | closed-source | |
| REX | Optience | Reactor Optimization and Kinetic Estimation | Windows | closed-source | |
| AVEVA Process Simulation (former SimCentral) | AVEVA | Steady state, Fluid flow and Dynamic process simulator. | Windows | closed-source | |
| SimCreate | TSC Simulation | Real time, first principle and generic operator training simulations, plant specific emulations and OPC for live plant connections. | Windows | closed-source | |
| Simulis Thermodynamics | Fives ProSim | Mixture properties and fluid phase equilibria calculations | Windows | closed-source | |
| SolidSim (Now in Aspen Plus) | SolidSim Engineering GmbH | Flowsheet simulation of solids processes | Windows | closed-source | |
| SPEEDUP | Aspen Technology | Dynamic process simulation | Unix, Windows | closed-source | |
| SuperPro Designer | Intelligen | Batch and continuous process simulation. | Windows | closed-source | |
| SysCAD | KWA Kenwalt Australia | Steady-state and dynamic process simulation | Windows | closed-source | |
| UniSim Design Suite | Honeywell | Process simulation and optimization | Windows | closed-source | |
| UniSim Competency Suite | Honeywell | Operator Competency Management and Training | Windows | closed-source | |
| USIM PAC | CASPEO | Steady-state simulation and optimization of processes | Windows | closed-source | |
| Virtuoso | Wood PLC | Multiphase dynamic process simulator for oil & gas production | Windows | closed-source | |
| VMG Symmetry | Schlumberger | Steady state simulation, dynamic process simulation, transient multiphase flowline simulation | Windows | closed-source | |
| Wolfram SystemModeler | Wolfram Research | Modelica-based Dynamic multidomain modelling (mechanical, electrical, chemical) | Windows, Mac, Linux | closed-source | |
| XPSIM | Process Simulation Services | Steady state and dynamic process simulation, transient multiphase pipeline simulator | Windows | closed-source | |