# List of Billboard number-one dance singles of 1999

These are the Billboard Hot Dance/Disco Club Play and Maxi-Singles Sales number-one hits of 1999.
| Issue date | Club Play Song | Artist | Maxi-Singles Sales | Artist |
| January 2 | "Believe" | Cher | "Believe" | Cher |
| January 9 | "Believe" | Cher | "Believe" | Cher |
| January 16 | "Up and Down" | Vengaboys | "Believe" | Cher |
| January 23 | "It's Not Right but It's Okay" | Whitney Houston | "Believe" | Cher |
| January 30 | "It's Not Right but It's Okay" | Whitney Houston | "Believe" | Cher |
| February 6 | "It's Not Right but It's Okay" | Whitney Houston | "Believe" | Cher |
| February 13 | "I'm Beautiful" | Bette Midler | "Believe" | Cher |
| February 20 | "I'm Beautiful" | Bette Midler | "I'm Beautiful" | Bette Midler |
| February 27 | "Skin" | Charlotte | "Believe" | Cher |
| March 6 | "(You Got Me) Burnin' Up" | Cevin Fisher featuring Loleatta Holloway | "Believe" | Cher |
| March 13 | "Nothing Really Matters" | Madonna | "Believe" | Cher |
| March 20 | "Nothing Really Matters" | Madonna | "Believe" | Cher |
| March 27 | "Jackie's Strength" | Tori Amos | "Believe" | Cher |
| April 3 | "Heartbreak Hotel" | Whitney Houston featuring Faith Evans and Kelly Price | "Believe" | Cher |
| April 10 | "I Still Believe" | Mariah Carey | "Believe" | Cher |
| April 17 | "Baby Wants to Ride" | Hani | "Believe" | Cher |
| April 24 | "Body" | Funky Green Dogs | "Blue Monday" | Orgy |
| May 1 | "Strong Enough" | Cher | "Believe" | Cher |
| May 8 | "It's Over Now" | Deborah Cox | "Livin' La Vida Loca" | Ricky Martin |
| May 15 | "It's Over Now" | Deborah Cox | "Livin' La Vida Loca" | Ricky Martin |
| May 22 | "Unspeakable Joy" | Kim English | "Livin' La Vida Loca" | Ricky Martin |
| May 29 | "Got the Groove" | SM-Trax | "Livin' La Vida Loca" | Ricky Martin |
| June 5 | "Sexual (Li Da Di)" | Amber | "Livin' La Vida Loca" | Ricky Martin |
| June 12 | "Big Love" | Pete Heller | "Livin' La Vida Loca" | Ricky Martin |
| June 19 | "Big Love" | Pete Heller | "Livin' La Vida Loca" | Ricky Martin |
| June 26 | "Big Love" | Pete Heller | "If You Had My Love" | Jennifer Lopez |
| July 3 | "Sing It Back" | Moloko | "If You Had My Love" | Jennifer Lopez |
| July 10 | "Sing It Back" | Moloko | "If You Had My Love" | Jennifer Lopez |
| July 17 | "What You Need" | Powerhouse featuring Duane Harden | "If You Had My Love" | Jennifer Lopez |
| July 24 | "Beautiful Stranger" | Madonna | "If You Had My Love" | Jennifer Lopez |
| July 31 | "Beautiful Stranger" | Madonna | "If You Had My Love" | Jennifer Lopez |
| August 7 | "I Will Go with You (Con te partirò)" | Donna Summer | "I Will Go with You (Con te partirò)" | Donna Summer |
| August 14 | "Red Alert" | Basement Jaxx | "Sexual (Li Da Di)" | Amber |
| August 21 | "Bailamos" | Enrique Iglesias | "Sexual (Li Da Di)" | Amber |
| August 28 | "My Love Is Your Love" | Whitney Houston | "Sexual (Li Da Di)" | Amber |
| September 4 | "My Love Is Your Love" | Whitney Houston | "Sexual (Li Da Di)" | Amber |
| September 11 | "Canned Heat" | Jamiroquai | "Sexual (Li Da Di)" | Amber |
| September 18 | "Five Fathoms (Love More)" | Everything but the Girl | "My Love Is Your Love" | Whitney Houston |
| September 25 | "Walking" | Pocket Size | "My Love Is Your Love" | Whitney Houston |
| October 2 | "All or Nothing" | Cher | "I Need To Know" | Marc Anthony |
| October 9 | "Situation '99" | Yazoo | "Heartbreaker" | Mariah Carey Featuring Jay-Z |
| October 16 | "Situation '99" | Yazoo | "Heartbreaker" | Mariah Carey Featuring Jay-Z |
| October 23 | "Situation '99" | Yazoo | "Heartbreaker" | Mariah Carey Featuring Jay-Z |
| October 30 | "Waiting for Tonight" | Jennifer Lopez | "Heartbreaker" | Mariah Carey Featuring Jay-Z |
| November 6 | "That's the Way Love Is" | Byron Stingily | "Heartbreaker" | Mariah Carey Featuring Jay-Z |
| November 13 | "Love Is the Healer" | Donna Summer | "Heartbreaker" | Mariah Carey Featuring Jay-Z |
| November 20 | "Sun Is Shining" | Bob Marley vs. Funkstar De Luxe | "Heartbreaker" | Mariah Carey Featuring Jay-Z |
| November 27 | "Sun Is Shining" | Bob Marley vs. Funkstar De Luxe | "Heartbreaker" | Mariah Carey Featuring Jay-Z |
| December 4 | "New York City Boy" | Pet Shop Boys | "Sexual (Li Da Di)" | Amber |
| December 11 | "Rendez-Vu" | Basement Jaxx | "Sexual (Li Da Di)" | Amber |
| December 18 | "Get Get Down" | Paul Johnson | "Sexual (Li Da Di)" | Amber |
| December 25 | "17 Again" | Eurythmics | "Sexual (Li Da Di)" | Amber |