# List of U.S. Routes in Ohio

U.S. Routes in Ohio are the components of the United States Numbered Highway System that are located in the U.S. state of Ohio. They are owned by the state, and maintained by the Ohio Department of Transportation (ODOT) except in cities.

## U.S. Routes

| Number | Length (mi) | Length (km) | Southern or western terminus | Northern or eastern terminus | Formed | Removed | Notes |
| US 6 | 248.09 | 399.26 | US 6 in Edgerton | US 6 in Pierpont | 01931-01-011931 | current | Also known as the Grand Army of the Republic Highway. |
| US 20 | 260.54 | 419.30 | US 20 near Edon | US 20 near Conneaut | 01926-01-011926 | current | |
| US 20N | — | — | — | — | — | — | |
| US 20S | — | — | — | — | — | — | |
| US 21 | — | — | US 21 in Marietta | US 6/US 20/US 42/US 322/US 422/ SR 3/SR 8/SR 14/SR 43/SR 87 in Cleveland | 01926-01-011926 | 01971-01-011971 | Replaced by I-77 |
| US 22 | 243.32 | 391.59 | West 9th Street and Central Avenue in Downtown Cincinnati | US 22 at the West Virginia state line (Veterans Memorial Bridge) in Steubenville | 01926-01-011926 | current | |
| US 23 | 234.83 | 377.92 | US 23 in Portsmouth | US 23 in Sylvania | 01926-01-011926 | current | |
| US 24 | 83.33 | 134.11 | US 24 at the Indiana state line | US 24 in Toledo | 01926-01-011926 | current | Fort-to-Port |
| US 25 | 208.18 | 335.03 | US 25 in Cincinnati | US 25 in Toledo | 01926-01-011926 | 01974-01-011974 | Enters Ohio via a bridge to Cincinnati from Kentucky; it is Kentucky maintained, however. In Ohio, US 25 was replaced by US 127, US 24, SR 25, CR 25A, and I-75. |
| US 27 | 40.54 | 65.24 | US 27 in Cincinnati | US 27 near College Corner | 01926-01-011926 | current | |
| US 30 | 247.01 | 397.52 | US 30 northeast of Monroeville, IN | US 30 at West Virginia state line (Jennings Randolph Bridge) in East Liverpool | 01926-01-011926 | current | |
| US 30N | — | — | — | — | 01932-01-011932 | 01974-01-011974 | |
| US 30S | — | — | — | — | 01932-01-011932 | 01974-01-011974 | Replaced by SR 309 |
| US 33 | 236.80 | 381.09 | US 33 near Wilshire | US 33 southeast of Pomeroy | 01937-01-011937 | current | |
| US 35 | 174.43 | 280.72 | US 35 near New Paris | US 35 in Gallipolis | 01934-01-011934 | current | |
| US 36 | 208.42 | 335.42 | US 36 near Palestine | US 250/SR 800 in Uhrichsville | 01926-01-011926 | current | |
| US 40 | 227.80 | 366.61 | US 40 near New Paris | US 40/US 250 in Bridgeport | 01926-01-011926 | current | |
| US 42 | 244.63 | 393.69 | US 25/US 42/US 127 in Cincinnati | Public Square, Cleveland | 01926-01-011926 | current | |
| US 50 | 204.24 | 328.69 | US 50 near Cleves | US 50 near Belpre | 01926-01-011926 | current | |
| US 50N | — | — | — | — | 01926-01-011926 | 01935-01-011935 | Replaced by US 50A and later SR 550 |
| US 50S | — | — | — | — | 01926-01-011926 | 01935-01-011935 | Replaced by US 50 |
| US 52 | 180.89 | 291.11 | I-74/US 52 near Harrison | US 52 in Chesapeake | 01926-01-011926 | current | |
| US 62 | 294.83 | 474.48 | US 62/US 68 near Aberdeen | US 62 in Masury | 01932-01-011932 | current | |
| US 68 | 178.97 | 288.02 | US 62/US 68 near Aberdeen | I-75/SR 15 in Findlay | 01933-01-011933 | current | |
| US 127 | 194.27 | 312.65 | US 25/US 42/US 127 in Cincinnati | US 127 near Alvordton | 01926-01-011926 | current | |
| US 223 | 0.66 | 1.06 | US 23, SR 51 & SR 184 in Sylvania | US 23/US 223 at the Michigan state line | 01930-01-011930 | current | Completely concurrent with US 23 in Ohio |
| US 224 | 238.50 | 383.83 | US 224 near Wren | US 224 near Lowellville | — | — | |
| US 250 | 161.81 | 260.41 | US 40/US 250 in Bridgeport | US 6 in Sandusky | — | — | |
| US 322 | 62.21 | 100.12 | Public Square, Cleveland | US 322 near Williamsfield | 01926-01-011926 | current | |
| US 422 | 74.94 | 120.60 | Public Square, Cleveland | US 422 near Campbell | 01926-01-011926 | current | |
| Former ||||||||

## Special routes

| Number | Length (mi) | Length (km) | Southern or western terminus | Northern or eastern terminus | Formed | Removed | Notes |
| US 6 Bus. | — | — | — | — | — | — | Serves Napoleon |
| US 6 Alt. | — | — | Sandusky | Huron | — | — | |
| US 6 Alt. | 7.30 | 11.75 | US 6 in Rocky River | Cleveland | 01969-01-011969 | current | |
| US 6 Alt. | — | — | Cleveland | East Cleveland | — | — | |
| US 6 Alt. | — | — | Euclid | Chardon | — | — | |
| US 20A | 52.44 | 84.39 | US 20 near Pioneer | US 20 near Toledo | 01935-01-011935 | current | |
| US 20 Bus. | — | — | Toledo | Gibsonburg Junction | — | — | |
| US 20 Truck | — | — | — | — | — | — | Served Perrysburg |
| US 20 Bus. | — | — | — | — | — | — | Serves Fremont |
| US 20A | — | — | Rocky River | Cleveland | — | — | |
| US 20A | — | — | Cleveland | East Cleveland | — | — | |
| Temp. US 21 | — | — | Cuyahoga Heights | Cleveland | — | — | |
| US 23 Truck | — | — | Kentucky-Ohio state line | Portsmouth | — | — | |
| US 23 Bus. | — | — | — | — | — | — | Serves Chillicothe |
| US 23 Bus. | — | — | Perrysburg | Toledo | — | — | |
| US 24 Alt. | — | — | Toledo | Ohio-Michigan state line | — | — | Originally Alt. US 25. |
| US 24 Bus. | — | — | Perrysburg | Toledo | — | — | |
| US 25 Bus. | — | — | Perrysburg | Toledo | — | — | |
| US 25 Bus. | — | — | Toledo | Ohio-Michigan state line | — | — | Later renamed Alt. US 24 |
| US 25 Bus. | — | — | — | — | — | — | Served Toledo |
| City US 27 | — | — | Kentucky-Ohio state line | Cincinnati | — | — | |
| Temp. US 27 | — | — | Kentucky-Ohio state line | Cincinnati | — | — | |
| US 27 Truck | — | — | — | — | — | — | Serves Cincinnati |
| US 30 Bus. | — | — | — | — | — | — | Serves Van Wert |
| US 30 Bus. | — | — | — | — | — | — | Serves Upper Sandusky |
| US 30 Bus. | — | — | — | — | — | — | Serves Bucyrus |
| US 30 Alt. | 2.22 | 3.57 | US 30 west of Dalton | US 30 east of Dalton | 01963-01-011963 | current | |
| US 33 Bus. | — | — | — | — | — | — | Serves Nelsonville |
| Temp. US 35 | — | — | West Virginia-Ohio state line | Kanauga | — | — | |
| US 35 Bus. | — | — | — | — | — | — | Serves Jackson |
| US 35 Bus. | — | — | — | — | — | — | Serves Xenia |
| US 35 Byp. | — | — | — | — | — | — | Served Xenia |
| Temp. US 36 | — | — | Baker | Greenville | — | — | |
| Temp. US 40 | — | — | Columbus | Bexley | — | — | |
| US 42 Alt. | — | — | Cincinnati | Sharonville | — | — | |
| US 50 Byp. | — | — | Cleves | Milford | — | — | |
| US 50 Truck | — | — | — | — | — | — | Served Cincinnati |
| US 50 Alt. | — | — | — | — | 01935-01-011935 | 01976-01-011976 | Replaced by SR 550 |
| US 50 Bus. | — | — | — | — | — | — | Served Belpre |
| US 52 Bus. | — | — | Hanging Rock | Coal Grove | — | — | |
| Temp. US 62 | — | — | — | — | 01998-01-011998 | current | Serves Alliance |
| US 68 Alt. | — | — | Kentucky-Ohio state line | Aberdeen | — | — | |
| US 68 Bus. | — | — | Kentucky-Ohio state line | Aberdeen | — | — | |
| US 68 Byp. | — | — | — | — | — | — | Served Springfield |
| US 127 Truck | — | — | — | — | — | — | Serves Cincinnati |
| US 127 Alt. | — | — | — | — | — | — | Served Hamilton |
| US 127 Bus. | — | — | — | — | — | — | Served Greenville |
| US 224 Bus. | — | — | — | — | — | — | Serves Van Wert |
| US 224 Alt. | — | — | Boardman | Poland | — | — | |
| US 250 Bus. | — | — | — | — | — | — | Serves New Philadelphia |
| Temp. US 250 | — | — | Silver Road Junction | Jefferson | — | — | |
| Former ||||||||