# South Carolina Highway 49

South Carolina Highway 49 (SC 49) is a 79.516-mile (127.969 km) primary state highway in the U.S. state of South Carolina. It is signed as a north–south highway, though it travels in a southwesterly–northeasterly direction, from Watts Mills to the North Carolina state line in Lake Wylie.

## Route description

SC 49 is part of a three-state highway 49 (including North Carolina Highway 49 and Virginia State Route 49) that totals 325 miles (523 km) from Watts Mills, South Carolina to Crewe, Virginia.
The portion in South Carolina runs 79+1⁄2 miles (127.9 km) from Watts Mills to Lake Wylie.

## History

Established in 1937 as a renumbering of SC 163, it traveled from U.S. Route 321 (US 321) in York to the North Carolina state line in Lake Wylie. In 1956, SC 49 was extended southwest to its current southern terminus at US 221 in Watts Mills replacing SC 91 from York to Monarch, SC 92 from Monarch to Cross Anchor, and SC 30 from Cross Anchor to Watts Mills.
In 1960 or 1961, SC 49 was rerouted from Lockhart to Mount Tabor. At an unknown date, SC 49 was rerouted north around downtown Union.
One previous SC 49 existed from around 1927–1935, from Myrtle Beach to the North Carolina state line in Little River. In 1932, most of SC 49 north of Myrtle Beach was replaced by US 117; by 1935, the rest of SC 49 (and US 117) was replaced by US 17.

## Major intersections

| County | Location | mi | km | Destinations | Notes |
| Laurens | Watts Mills | 0.000 | 0.000 | US 221 (Lucas Avenue) – Laurens, Woodruff | Southern terminus |
| Laurens | ​ | 2.530 | 4.072 | I-385 – Columbia, Greenville | I-385 exit 5 |
| Laurens | ​ | 4.840 | 7.789 | SC 308 – Clinton | |
| Spartanburg | ​ | 9.353 | 15.052 | I-26 – Columbia, Spartanburg | I-26 exit 44 |
| Spartanburg | ​ | 10.400 | 16.737 | SC 92 west – Enoree | Eastern terminus of SC 92 |
| Spartanburg | Cross Anchor | 12.590 | 20.262 | SC 56 – Woodruff, Clinton | |
| Union | Union | 27.750 | 44.659 | SC 496 east (Industrial Park Road/SC 49 Truck) | Western terminus of SC 496 and southern terminus of SC 49 Truck |
| Union | Union | 28.430 | 45.754 | US 176 east / SC 215 south (Duncan Bypass/SC 49 Truck) / West Main Street – Whitmire | South end of US 176/SC 215 overlap and northern terminus of SC 49 Truck |
| Union | Union | 29.180 | 46.961 | US 176 west / SC 215 north (Duncan Bypass) / Rice Avenue – Spartanburg | Northern end of US 176 and SC 215 overlap |
| Union | Union | 29.970 | 48.232 | SC 18 (Thompson Boulevard) – Jonesville, Union | |
| Union | Monarch Mill | 32.090 | 51.644 | SC 49 Conn. south (Monarch Avenue) – Carlisle | Northern terminus of SC 49 Connector |
| Union | ​ | 39.010 | 62.781 | SC 105 north (Mount Tabor Church Road) | Southern terminus of SC 105 |
| Union | Lockhart | 41.540 | 66.852 | SC 9 north (Jonesville-Lockhart Highway) – Jonesville | Southern end of SC 9 overlap |
| Chester | ​ | 42.250 | 67.995 | SC 9 south (Pinckney Road) | Northern end of SC 9 overlap |
| York | Bullock Creek | 47.480 | 76.412 | SC 322 east (McConnells Highway) – McConnells | Western terminus of SC 322 |
| York | ​ | 50.550 | 81.352 | SC 97 – Hopewell | |
| York | Sharon | 55.940 | 90.027 | SC 211 north (Hickory Grove Road) – Hickory Grove | Southern terminus of SC 211 |
| York | York | 61.940 | 99.683 | US 321 – Gastonia | |
| York | York | 62.310 | 100.278 | US 321 Bus. south (Congress Street) – Chester | Southern end of US 321 Bus. overlap |
| York | York | 62.830 | 101.115 | SC 5 Bus. / SC 161 Bus. (Liberty Street) | |
| York | York | 63.210 | 101.727 | US 321 Bus. north (Kings Mountain Street) – Gastonia | Northern end of US 321 Bus. overlap |
| York | York | 64.826 | 104.327 | SC 5 / SC 161 – Rock Hill, Blacksburg | |
| York | ​ | 74.146 | 119.326 | SC 274 east (Hands Mill Highway) – Rock Hill | Southern end of SC 274 overlap |
| York | ​ | 74.346 | 119.648 | SC 55 west – Clover | Eastern terminus of SC 55 |
| York | Lake Wylie | 76.396 | 122.947 | SC 274 west / SC 557 south – Clover, Gastonia | Northern end of SC 274 overlap; eastern terminus of SC 557 |
| Catawba River / Lake Wylie | Catawba River / Lake Wylie | 79.516 | 127.969 | NC 49 north (York Road) – Charlotte | Northern terminus |
| Buster Boyd Bridge; South Carolina–North Carolina state line ||
| 1.000 mi = 1.609 km; 1.000 km = 0.621 mi Concurrency terminus ||||||

## Special routes
### Union truck route

South Carolina Highway 49 Truck (SC 49 Truck) is a 1.790-mile (2.881 km) truck route that bypasses a portion of West Main Street (SC 49) in western portions of Union. The first 0.760 miles (1.223 km) of the highway travels along the two-lane Industrial Park Road, concurrent with the unsigned designation of SC 496. It then turns to the north-northwest along US 176/SC 18 Truck/SC 215 (Duncan Bypass) for its last 1.030 miles (1.658 km).
The entire route is in Union, Union County.
| mi | km | Destinations | Notes |
| 0.000 | 0.000 | SC 49 / Industrial Park Road north | Western end of SC 496 concurrency; western terminus of SC 49 Truck and SC 496 |
| 0.770 | 1.239 | Duncan Bypass south (US 176 east / SC 18 Truck south / SC 215 south) / Main Street east (SC 496 east) | Eastern end of SC 496 concurrency; western end of US 176/SC 18 Truck/SC 215 concurrency |
| 1.790 | 2.881 | SC 49 south (West Main Street west) – Laurens US 176 west / SC 18 Truck north / SC 215 north / SC 49 north (Duncan Bypass north) – Spartanburg West Main Street east – Union | Eastern end of US 176/SC 18 Truck/SC 215 concurrency; eastern terminus; provides access to Union Medical Center |
| 1.000 mi = 1.609 km; 1.000 km = 0.621 mi Concurrency terminus ||||

### Monarch Mill connector route

South Carolina Highway 49 Connector (SC 49 Conn.) is a 3.090-mile-long (4.973 km) connector route along Monarch Highway between SC 215 southeast of Union to SC 49 in the census-designated place of Monarch Mill.