# Mississippi Highway 25

Mississippi Highway 25 (MS 25) runs from I-55 in Jackson, Mississippi to the Tennessee state line north of Iuka. The largely controlled-access part from Jackson to Starkville connects the state capital with the main campus of Mississippi State University.

## History

The 1933 Road Map of Mississippi shows MS 25 running northward from Macon roughly along the 2019 alignment of U.S. Route 45 to Brooksville, then roughly along the 2019 alignment of U.S. Route 45 Alternate through Artesia and West Point to Muldon, where the 2019 alignment continues in a northeasterly direction.
As of June 28, 2006, 150 miles (240 km) of continuous four-lane divided highway is open between Starkville, Mississippi, and Jackson, Mississippi. The last leg to open was the 11.9-mile (19.2 km), $27-million section from the intersection of Highway 19 north of Louisville, Mississippi, to Noxapater Creek in Winston County. This is one of the culminations of the 1987 Four-Lane Highway Program (commonly referred to as AHEAD Program) for improving Mississippi roadways.
On May 10, 2006, the next-to-last leg, a 10.1-mile (16.3 km), $23-million section, opened from the Oktibbeha County line west into Winston County.
Legally, Mississippi 25 is defined in Mississippi Code Annotated § 65-3-3, as follows: "Begins at or near Jackson, Hinds County, thence in a northeasterly direction to or near Carthage, Louisville and Starkville, thence along U.S. 82 to its intersection with U.S. 45A, thence along U.S. 45A to Muldon, thence to or near Aberdeen, Amory, Smithville, to U.S. 78, thence continuing to Belmont, Dennis, Tishomingo, Iuka and to the Mississippi-Tennessee state line north of Cross Roads, Tishomingo County."

## Major intersections

| County | Location | mi | km | Destinations | Notes |
| Hinds | Jackson | 0.0 | 0.0 | I-55 / Lakeland Drive west – McComb, Grenada | I-55 exit 98B; Southern terminus |
| Hinds | Jackson | 0.8 | 1.3 | Lakeland Terrace - LeFleur's Bluff State Park | Access road into park |
| Rankin | Flowood | 2.7 | 4.3 | MS 477 south (Treetops Boulevard) | Northern terminus of unsigned MS 477 |
| Rankin | Flowood | 4.4 | 7.1 | MS 475 south to I-20 – USPFO, International Airport | Northern terminus of MS 475 |
| Rankin | ​ | 12.3 | 19.8 | MS 471 south / MS 471 Bus. north – Brandon | Interchange; south end of MS 471 overlap; southern terminus of MS 471 Bus; south end of expressway |
| Rankin | ​ | 19.5 | 31.4 | MS 471 north – Goshen Springs | Interchange; north end of MS 471 overlap |
| Rankin | Koch | 22.0 | 35.4 | MS 43 – Canton, Sand Hill | Interchange |
| Leake | ​ | 34.4 | 55.4 | To MS 483 south – Leake County Water Park, Ludlow, Ross Barnett Reservoir Low Head Dam | |
| Leake | ​ | 42.3 | 68.1 | MS 13 south – Lena, Morton | Northern terminus of MS 13 |
| Leake | Wiggins, Leake County | 45.3 | 72.9 | MS 16 – Canton, Carthage | Interchange |
| Leake | ​ | 50.6 | 81.4 | To MS 429 – Thomastown | |
| Leake | Carthage | 58.1 | 93.5 | MS 35 – Kosciusko, Carthage | Interchange |
| Leake | ​ | 72.6 | 116.8 | Remus Road | Proposed MS 427 |
| Winston | Four Corners | 77.1 | 124.1 | MS 19 – Kosciusko, Philadelphia, Meridian | Interchange |
| Winston | Louisville | 97.7 | 157.2 | MS 15 south – Philadelphia | Interchange; south end of MS 15 overlap |
| Winston | Louisville | 98.6 | 158.7 | MS 14 – Kosciusko, Downtown Louisville, Macon | |
| Winston | ​ | 100.8 | 162.2 | MS 15 north / MS 758 west – Ackerman, Mathiston | Interchange; north end of MS 15 overlap; eastern terminus of MS 758 |
| Oktibbeha | Starkville | 130.7 | 210.3 | MS 12 – Starkville, Ackerman, Mississippi State University | Interchange |
| Oktibbeha | Starkville | 132.1 | 212.6 | MS 182 – West Starkville | Interchange |
| Oktibbeha | Starkville | 132.7 | 213.6 | US 82 west – Winona | Interchange; south end of US 82 overlap; south end of freeway; north end of expressway |
| Oktibbeha | Starkville | 134 | 216 | MS 389 – Downtown Starkville | |
| Oktibbeha | ​ | 136.1 | 219.0 | MS 12 west – Starkville, Mississippi State University | South end of MS 12 overlap |
| Oktibbeha | ​ | 140 | 230 | MS 182 – Clayton Village, Starkville | |
| Oktibbeha | ​ | 142.6 | 229.5 | Hickory Grove Road | |
| Lowndes | ​ | 144.3 | 232.2 | US 82 east / MS 12 east / US 45 Alt. south – Columbus, Meridian | Interchange; north end of US 82 overlap; south end of US 45 Alt. overlap; north end of freeway |
| Clay | West Point | 152.6 | 245.6 | MS 50 – Downtown West Point, Waverley Plantation | |
| Monroe | ​ | 160.3 | 258.0 | US 45 Alt. north – Okolona, Tupelo | Interchange; north end of US 45 Alt. overlap |
| Monroe | ​ | 168.4 | 271.0 | MS 382 west – Prairie | Eastern terminus of MS 382 |
| Monroe | Aberdeen | 169.9 | 273.4 | US 45 north / MS 8 west – Tupelo | South end of US 45 / MS 8 overlap |
| Monroe | Aberdeen | 172.1 | 277.0 | MS 145 north – Aberdeen | Southern terminus of MS 145 |
| Monroe | Aberdeen | 174.3 | 280.5 | US 45 south – Columbus | Interchange; north end of US 45 overlap |
| Monroe | ​ | 175.4 | 282.3 | MS 8 east – Gattman | North end of MS 8 overlap |
| Monroe | Amory | 186.1 | 299.5 | US 278 east | South end of US 278 overlap |
| Monroe | Amory | 187.7 | 302.1 | US 278 west – Tupelo | North end of US 278 overlap |
| Monroe | Amory | 188.8 | 303.8 | MS 6 west – Nettleton | Eastern terminus of MS 6 |
| Monroe | Smithville | 197.2 | 317.4 | MS 23 north | Southern terminus of MS 23 |
| Itawamba | Fulton | 210.8 | 339.2 | I-22 west / US 78 west – Tupelo, Downtown Fulton, Jamie L. Whitten Historical Center, Itawamba Community College | South end of I-22 / US 78 overlap; MS 25 south follows exit 104 |
| Itawamba | ​ | 215.8 | 347.3 | I-22 east / US 78 east – Birmingham | North end of I-22 / US 78 overlap; MS 25 north follows exit 108 |
| Itawamba | ​ | 216.8 | 348.9 | MS 178 – Fulton, Tremont | |
| Itawamba | ​ | 221.8 | 357.0 | MS 76 east – Russellville | Western terminus of MS 76 |
| Tishomingo | ​ | 231.8 | 373.0 | Tishomingo County 78 | Proposed MS 767 |
| Tishomingo | Belmont | 232.2 | 373.7 | MS 760 east to MS 366 – Golden, Red Bay | Western terminus of unsigned MS 760 |
| Tishomingo | Belmont | 233.8 | 376.3 | MS 366 east – Golden, Red Bay | Western terminus of MS 366 |
| Tishomingo | Dennis | 237.8 | 382.7 | MS 4 west – New Site | Eastern terminus of MS 4 |
| Tishomingo | ​ | 240.8 | 387.5 | Natchez Trace Parkway | Interchange |
| Tishomingo | ​ | 244.8 | 394.0 | MS 30 – Paden Overlook, Crows Neck | |
| Tishomingo | Midway | 249.8 | 402.0 | MS 364 west – Holcut, Divide Section Wildlife Management Area Headquarters, Holcut Memorial | Eastern terminus of MS 364 |
| Tishomingo | Iuka | 254.8 | 410.1 | US 72 – Corinth, Florence, AL | Interchange |
| Tishomingo | Iuka | 255.2 | 410.7 | MS 25 Bus. north (Battleground Drive) | Southern terminus of MS 25 Business |
| Tishomingo | Iuka | 255.8 | 411.7 | MS 172 – Iuka, Old Court House Museum | |
| Tishomingo | Iuka | 256.8 | 413.3 | County Road 231 - Harmony | |
| Tishomingo | ​ | 257.8 | 414.9 | MS 25 Bus. south | Northern terminus of MS 25 Bus. |
| Tishomingo | Cross Roads | 264.8 | 426.2 | MS 365 south – Burnsville | Northern terminus of MS 365 |
| Tishomingo | ​ | 267.8 | 431.0 | MS 350 west – Corinth | Eastern terminus of MS 350 |
| Tishomingo | ​ | 269.8 | 434.2 | SR 57 west – Pickwick Dam | Tennessee state line; northern terminus |
| 1.000 mi = 1.609 km; 1.000 km = 0.621 mi Concurrency terminus ||||||

## Related route
### Iuka business route

Mississippi Highway 25 Business (MS 25 Bus.) is an earlier alignment of MS 25. It is an unsigned highway called Battleground Drive. The southern terminus at MS 25 is just outside of Downtown Iuka, where it intersects with MS 172; the northern terminus is at MS 25 north of Iuka.

### Major intersections

The entire route is in Iuka, Tishomingo County.
| mi | km | Destinations | Notes |
| 0.00 | 0.00 | MS 25 | Southern terminus |
| 1.0 | 1.6 | MS 172 | |
| 2.7 | 4.3 | MS 25 | Northern terminus |
| 1.000 mi = 1.609 km; 1.000 km = 0.621 mi ||||