# U.S. Route 441 in Florida

U.S. Route 441 (US 441) in Florida is a north–south United States Highway. It runs 433 miles (697 km) from Miami in South Florida northwest to the Georgia state line, with the overall route continuing to Tennessee in the Rocky Top area.
Like all AASHTO designated highways in Florida, US 441 always carries a FDOT designated hidden state road number:
* State Road 7 (SR 7) from the US route's southern terminus at US 41/SR 90 in Miami to Southern Boulevard (US 98/SR 80) in Royal Palm Beach.
* State Road 80 from SR 7 in Royal Palm Beach to Main Street (SR 15) in Belle Glade.
* State Road 15 from Hooker Highway (SR 812/SR 80) in Belle Glade to Narcoosee Road (County Road 15 or CR 15) in St. Cloud.
* State Road 500 from the intersection with Irlo Bronson Memorial Highway (US 192) in Holopaw to Bonnie Heath Boulevard (US 27/SR 492) in Ocala.
* State Road 25 from North 14th Street (US 27) in Leesburg to the junction with US 41/US 441 Truck in Columbia County, with the following exception:
** State Road 25A between the junctions of CR 25 north in Lady Lake and SR 25 south in Belleview.
* State Road 25A from US 41/US 441 Truck to CR 25A north in Five Points.
* State Road 47 from Duval Street (US 90/SR 10) in Lake City to Georgia State Route 89 at the Georgia state line.
Concurrences with U.S. routes include US 98 from Royal Palm Beach to Okeechobee, within the vicinity of Lake Okeechobee, US 192 between Holopaw and Kissimmee, US 17-92 from Kissimmee to Orlando, SR 44 from Mount Dora to Leesburg, US 27 from Leesburg to Ocala, US 301 from Belleview to near Sparr, and US 41 from High Springs to Lake City.

## Route description
### Miami to Kissimmee

US 441 begins its northward journey at Southwest 7th and 8th Streets (US 41 both directions) in the east section of the "Little Havana" neighborhood of downtown Miami (both are one-way streets). 441 runs along SW/NW 8th Ave. till it crosses the Miami River; then it runs along NW 7th Ave. till the Golden Glades interchange; then it runs along NW 2nd Ave. till the Miami-Dade/Broward county line. The route is concurrent with SR 7 from its southern terminus and parallels Interstate 95 (I-95) north out of Miami to western Aventura, where I-95 heads northeast to access Fort Lauderdale and the remainder of the eastern Florida coast. However, the route is soon joined by the tolled Florida's Turnpike and I-95 (Exits 12 and 12C), which follows US 441 north to Royal Palm Beach (ten miles west of West Palm Beach). In between, the route interchanges with the Turnpike at exit 62 via State Road 870 (Commercial Blvd.) in Tamarac. Additionally, US 441 meets Interstate 595 (Exits 8 and 8B) west of Fort Lauderdale and the tolled State Road 869 in Coconut Creek.
At Royal Palm Beach, US 441 intersects U.S. Route 98, ending the concurrency with SR 7, and overlaps the highway through central Palm Beach County, along with hidden State Road 80. Near Twenty Mile Bend SR 700 branches off to the northwest, which is where U.S. Routes 98 and 441 split until 2007. US 98-441 continues west to Belle Glade at the intersection of State Road 15, along the eastern shore of Lake Okeechobee, where SR 80 turns south and US 98-441 turns north to follow the shoreline to Pahokee. Just north of Pahokee in Canal Point, SR 700 rejoins US 98-441 and remains concurrent with US 441 along the eastern edge of the lake. North of Lake Okeechobee in Okeechobee, US 98 splits away from US 441 making a left turn at State Road 70, shortly afterwards the Okeechobee Amtrak station can be found. US 441 continues north, meeting the Turnpike at Yeehaw Junction in Osceola County (via State Road 60). It passes through the community of Kenansville prior to intersecting U.S. Route 192 at Holopaw. US 441 turns west onto US 192, forming an overlap into Kissimmee.

### Kissimmee to Mount Dora

At Kissimmee US 441 separates from US 192 and joins US 17/92, here known as the Orange Blossom Trail or OBT. The OBT starts on US 17/92 at the Polk County/Osceola County line a few miles south of Kissimmee. These names are used throughout Central Florida for the length of US 441 within the region.
Due to its proximity with Walt Disney World and affiliated resorts as well as Sea World, Universal Studios, and others, US 17/US 92/US 441 intersects many toll roads between Kissimmee and Orlando, the first of which is the partially tolled and partial limited-access Osceola Parkway in Kissimmee. Immediately after entering Orange County, it intersects SR 417 (Central Florida GreeneWay) at exit 11. Just north of the intersection the Central Florida Parkway leads to Sea World. Neither of these intersections or interchanges however, compare to the combined interchanges of Florida's Turnpike and SR 528 (Beachline Expressway), in Sky Lake, which contains a series of convoluted interchanges and partial ramps from side roads. North of this interchange, the road passes west of The Florida Mall and intersects SR 482.
In Holden Heights, US 441 has an interchange with I-4 (Exit 80). Eastbound access from I-4 comes from partial cloverleaf ramps, and westbound access comes from a left-turn ramp between the two carriageways that runs under the eastbound lane and merges with the east to southbound ramp before merging with southbound OBT. The interchange provides no south to east access and no west to north access, but such access can found from the intersection with West Michigan Street. Further north the road heads into Orlando and comes to the interchange with SR 408 (East-West Tollway) at exit 9, which is a diamond interchange. After curving around Givens Street and Springdale Road, both of which can only be accessed from West Concord Street, OBT moves closer to a parallel railroad freight line and meets the intersection of SR 50 (Colonial Drive) northwest of downtown. Here, US 17/92 turns east onto State Road 50 while US 441 continues north on the Orange Blossom Trail. North of downtown, US 441 encounters intersections with State Road 438, then State Road 416, and after running along the western edge of Lake Fairview, an intersection with State Road 423 which changes from the north-and-south John Young Parkway to the east-and-west Lee Road.
The road moves away from the freight line north of SR 423, but in Lockhart it runs over a bridge for that line again between Rose Avenue and Beggs Road. Further northwest it runs beneath an interchange with State Road 414, then cuts through a corner of Seminole County and re-enters Orange County in Apopka where it meets the northern terminus of West Orange Trail and the tolled State Road 429 before leaving the Orlando area. This road was intended to be part of the Central Florida GreeneWay loop around the Orlando Metropolitan Area. The road cuts through Plymouth and back to Apopka again, but the last sites in Apopka are Orlando Apopka Airport along the west side and Zellwood Cemetery on the east side before entering Zellwood, Florida. Intersections here include Ponkan Road and then Jones Avenue which lead to another airport known as Bob White Field The road takes a slight reverse curve before the intersection with Sadler Avenue (CR 448), and then approaches Lake Ola in Tangerine, where the road turns straight north. At the junction with County Road Old 441 (former State Road 500A), US 441 finally loses its designation as the Orange Blossom Trail, then crosses the Orange-Lake County Line and enters Mount Dora. CR Old 441 remains a local downtown street in Mount Dora, but US 441 continues as a rural at-grade four-lane divided highway.

### Mount Dora to Sparr

Continuing with the rural surroundings, US 441 maintains its straight north and south position until it curves to the northwest between Lincoln and East Pine Avenues. Approaching Loch Leven, it turns straight west, and then State Road 44 joins US 441 after having run west from New Smyrna Beach and DeLand. This intersection is also shared with County Road 44B, which takes motorists to Downtown Mount Dora. In southern Eustis, US 441-SR 44 encounter another un-numbered interchange with State Road 19 and County Road 19A, taking SR 19 in a wrong way concurrency until it reaches a wye in Tavares, where SR 19 heads south toward Howey-in-the-Hills and Groveland, and County Road Old 441 rejoins US 441. From here, US 441-SR 44 is a six-lane highway with bicycle lanes that squeezes between Lake Harris and Lake Eustis where it crosses over the Dead River on a bridge between the two lakes. The road passes by Leesburg Municipal Airport, then serves as the western terminus of County Road 44, all the while winding around the northern shores of Lake Harris. In Leesburg, SR 44 leaves US 441 heading toward Wildwood, Inverness, and Crystal River, while US 441 curves to the northwest, then intersects U.S. Route 27 in another concurrency, and as a result, the hidden state routes are officially SR 25-500. The concurrency with SR 25 is short-lived, because in Lady Lake, SR 25 branches away as County Road 25. This once served as the southern terminus of the US 27-441 Alternate Route around Lake Weir into Belleview, but still remains a scenic route.
Around the Lake-Marion county border, US 27-441 enters a retirement community known as The Villages. Because of the frequent use of street-legal golf cars in the community, bridges and tunnels for these carts can be found throughout the road. US 27-441 leaves The Villages as it approaches County Road 42, a bi-county east-west scenic route through Central Florida. North of here, it serves as the eastern terminus of a newly constructed bypass to CR 484 in Summerfield. Within Belleview, the road encounters two somewhat important intersections; County Road 25A, and then State Road 35. SR 35 joins US 27-441 in a wrong-way concurrency with SR 500 as the road curves more to the west, until it reaches the intersection with US 301, where SR 35 turns south, and SR 500 becomes the hidden state road for US 27-301-441 for a few blocks. However SR 25 reunites with the triplex at the former eastern terminus of CR 484, and shares a concurrency with SR 25, and US 27-301-441's new secret route becomes SRs 25-500 once again. After that the road curves more to the north again. Near the right of way for the formerly proposed Cross Florida Barge Canal in Santos, the median for the road widens, as it contains supports for a bridge that was never completed once the Canal project was cancelled. Before the median narrows back down to normal again, it intersects CR 328, where a police station exists in the median. To the west of this intersection is the Santos Trail System trailhead of the Cross Florida Greenway.
Before US 27-301-441 enters Ocala, it veers off to the left at an intersection with County Road 464A (Southeast Lake Weir Avenue), a former segment of US 441 that eventually leads to Ocala Union Station. The first major intersection after this is 31st Street. Then it crosses under a railroad bridge before reaching the City Limits and the intersections with the northern terminus of CR 475 and crossing SR 464 (17th Street). US 27-301-441 intersects with SR 200 (becoming the new hidden state road until US 301 reaches US 1-23). The highway reaches the heart of Ocala at the intersection with SR 40 (West Silver Springs Boulevard). After this, the road crosses a railroad bridge west of Ocala Union Station. Five blocks later, it reaches the intersection of SR 492 (Northwest 10th Street) only to move in the opposite direction, leaving the US 301-441 overlap and taking SR 500 with it as they head northwest towards Williston, Perry, Tallahassee, and points north. Before US 301-441 leaves Ocala, it has an intersection with County Road 200A (Northwest 20th Street), which runs east and then north. This road was the former State Road 200A and decommissioned U.S. Route 301 Alternate.
After County Road 464A (North Magnolia Avenue) terminates at the southeast corner of the intersection of US 301-441 and Northwest 28th Street, another county alternate which was a former section of US 441-SR 25 begins on the opposite side. This road is CR 25A (Northwest Gainesville Road), which is also the decommissioned U.S. Route 441 Alternate, and runs northwest through towns such as Zuber, Lowell, and Reddick. East of Zuber, the road intersects SR 326, which originally had a short concurrency, but now directly crosses US 301-441. South of the intersection with CR 329 is an interchange with U.S. Route 441 between Sparr and Lowell, where the US 301-441 concurrency ends. US 301 moves northeast towards Waldo, Starke, and Jacksonville taking SR 200 with it, while US 441 moves northwest.

### Reddick to the state line

In Reddick US 441 continues to the northwest, serving as the northern terminus of CR 25A. From there it intersects CR 318, which provides access to I-75 in Irvine to the west and Salt Springs in Ocala National Forest to the east. The road then runs through communities such as Orange Lake and McIntosh, where it passes through the McIntosh Historic District before crossing the Marion-Alachua County Line near the town of Evinston. It passes by a turnoff to Cross Creek before entering Micanopy, then runs across Paynes Prairie Preserve State Park and goes through Gainesville as 13th Street, serving as the eastern edge of the University of Florida campus. After intersecting SR 331 and later SRs 24A-226, State Road 24 joins US 441 in a brief concurrency until it reaches State Road 26 and turns east. US 441 continues north as it becomes the western terminus of State Road 120, then intersects State Road 222 before curving to the northwest and finally joining State Road 20, thereby converting it into an additional hidden state road. At the intersection of SR 121, the DeSoto Trail moves from SR 121 to US 441. In Alachua, US 441 intersects with SR 235, and then runs under an interchange with Interstate 75 (Exit 399), with quarter-cloverleaf interchanges on the northeast and northwest corners.
Just as it did in Leesburg, US 441 in High Springs curves to the right while a state road becomes independent, specifically SR 20, which runs west only to join US 27 as they head towards Perry, Tallahassee, and Niceville. Meanwhile, as it did with US 27 in Leesburg, US 441 joins US 41 north, but here it also serves as the northern terminus of hidden SR 45. US 41-441 crosses the Santa Fe River then runs north passing by O'Leno State Park and River Rise Preserve State Park, near which it shares a brief concurrency with State Road 18. It then runs through Ellisville, where it has another interchange with I-75 (Exit 414), just south of the western terminus of State Road 238.
Entering Lake City, US 441 splits from US 41 onto State Road 25A south of the city. The routes remain parallel, and at the US 90 Lake City Truck Route, Route 441 is joined by State Road 47 which was signed as terminating at US 41. The first intersection within this new hidden route is at U.S. Route 90 (where the DeSoto Trail heads west) to the northern extents of Lake City. Past Lake City, SR 25 branches off to the northwest as County Road 25A, which also shares intersections with CR 250 to the east and Northeast Double Run Road to the northeast. US 441 has an interchange with Interstate 10 (Exit 303), then skirts the western edge of the Okefenokee Swamp and east bank of the Suwannee River as it enters Georgia.

## History

From 1956, signs for U.S. Highways in Florida had different colors for each highway. The "shield" for US 441 was brown, until the state was forced by the federal government to conform to standards that required consistent black-and-white signs in 1993.
Between 2007 and 2011, the Florida Department of Transportation rebuilt the NW 7th Avenue Bridge over the Miami River.

## Major intersections

| County | Location | mi | km | Destinations | Notes |
| Miami-Dade | Miami | 0.000 | 0.000 | US 41 east (Southwest 8th Street) | SW 8th Avenue continues south; southern terminus of SR 7 |
| Miami-Dade | Miami | 0.066 | 0.106 | US 41 west (Southwest 7th Street) | |
| Miami-Dade | Miami | 0.464 | 0.747 | SR 968 east (Southwest 1st Street) | |
| Miami-Dade | Miami | 0.532 | 0.856 | SR 968 west (Flagler Street) | |
| Miami-Dade | Miami | 0.87 | 1.40 | Fifth Street Bridge over Miami River | Fifth Street Bridge over Miami River |
| Miami-Dade | Miami | 3.075 | 4.949 | US 27 (Northwest 36th Street) | |
| Miami-Dade | Miami | 4.126 | 6.640 | SR 944 (Northwest 54th Street) to I-95 | |
| Miami-Dade | Miami | 5.649 | 9.091 | SR 934 (Northwest 79th Street) to I-95 | Two-way street carries only SR 934 eastbound but is signed from US 441 to SR 934 west |
| Miami-Dade | ​ | 5.773 | 9.291 | SR 934 west (Northwest 81st Street) | |
| Miami-Dade | Pinewood | 7.171 | 11.541 | To SR 932 (Northwest 103rd Street) / I-95 | |
| Miami-Dade | North Miami | 8.171 | 13.150 | SR 924 (Gratigny Road) to I-95 | |
| Miami-Dade | North Miami | 8.546 | 13.753 | SR 922 east (North Miami Boulevard) to I-95 | Western terminus of SR 922 |
| Miami-Dade | North Miami | 9.172 | 14.761 | To SR 916 east (Northwest 135th Street) / I-95 – Airport | |
| Miami-Dade | North Miami | 9.273 | 14.923 | SR 916 west (Opa-locka Boulevard) | |
| Miami-Dade | Golden Glades | 10.9 | 17.5 | SR 9 south – Opa-locka | No northbound exit; southern terminus of concurrency with SR 9 |
| Miami-Dade | Golden Glades | 11.1 | 17.9 | Florida's Turnpike north / SR 826 west | No southbound exit |
| Miami-Dade | Golden Glades | 11.4 | 18.3 | SR 826 east – Beaches | |
| Miami-Dade | North Miami Beach | 11.8 | 19.0 | I-95 (SR 9 north) | Same-directional movements only; northern terminus of SR 9A; northern terminus of concurrency with SR 9 |
| Miami-Dade | Miami Gardens | 12.044 | 19.383 | To Northwest 7th Avenue Extension west / SR 826 north / Florida's Turnpike / Florida's Turnpike Extension | |
| Miami-Dade | Miami Gardens | 12.604 | 20.284 | SR 860 (Miami Gardens Drive) to I-95 | |
| Miami-Dade | Miami Gardens | 13.598 | 21.884 | To I-95 / Honey Hill Drive / Ives Dairy Road | Former SR 854 |
| Miami-Dade–Broward county line | Miami Gardens–West Park– Miramar tripoint | 14.680 | 23.625 | SR 852 west (County Line Road) to Florida's Turnpike | Eastern terminus of SR 852 |
| Broward | Miramar–West Park line | 15.492 | 24.932 | SR 858 east (Hallandale Beach Boulevard) / CR 858 west (Miramar Parkway) to I-95 / SR A1A / I-75 | Eastern terminus of CR 858; western terminus of SR 858 |
| Broward | Miramar–West Park– Hollywood tripoint | 16.228 | 26.116 | SR 824 (Pembroke Road) to I-95 | |
| Broward | Hollywood | 17.258 | 27.774 | SR 820 (Hollywood Boulevard) to I-95 / Florida's Turnpike | |
| Broward | Hollywood | 18.771 | 30.209 | SR 822 east / CR 822 west (Sheridan Street) to I-95 | |
| Broward | Hollywood | 19.770 | 31.817 | SR 848 (Stirling Road) to I-95 | |
| Broward | Hollywood–Davie line | 20.906 | 33.645 | SR 818 (Griffin Road) to I-95 / Florida's Turnpike | |
| Broward | Davie–Fort Lauderdale– Broadview Park tripoint | 22.47 | 36.16 | I-595 / SR 84 to Florida's Turnpike | |
| Broward | Fort Lauderdale–Broadview Park line | 23.822 | 38.338 | SR 736 east (Davie Boulevard) to US 1 / I-95 | Western terminus of SR 736 |
| Broward | Plantation | 24.964 | 40.176 | SR 842 (Broward Boulevard) to I-95 / US 1 / SR 817 | |
| Broward | Lauderhill–Plantation line | 25.99 | 41.83 | SR 838 (Sunrise Boulevard) to I-95 / Florida's Turnpike | Interchange |
| Broward | Lauderdale Lakes | 27.980 | 45.029 | SR 816 (Oakland Park Boulevard) to I-95 | |
| Broward | Tamarac | 29.474 | 47.434 | SR 870 (Commercial Boulevard) to I-95 / Florida's Turnpike / SR 869 | |
| Broward | North Lauderdale | 30.90 | 49.73 | McNab Road / Northwest 62nd Street | interchange |
| Broward | Margate | 32.837 | 52.846 | SR 814 east / CR 814 west (Atlantic Boulevard) to I-95 / Florida's Turnpike / SR 869 (Sawgrass Expressway) | |
| Broward | Margate | 33.529 | 53.960 | To Florida's Turnpike / Coconut Creek Parkway (CR 912 east) | Western terminus of unsigned CR 912 |
| Broward | Margate–Coral Springs– Coconut Creek tripoint | 35.57 | 57.24 | SR 834 (Sample Road) to I-95 / Florida's Turnpike | Interchange |
| Broward | Coconut Creek–Coral Springs– Parkland tripoint | 37.36 | 60.13 | SR 869 (Sawgrass Expressway) to Florida's Turnpike – Miami, West Palm Beach | SR 869 exit 18 |
| Broward | Coconut Creek–Parkland line | 38.563 | 62.061 | SR 810 east (Hillsboro Boulevard) to I-95 | Western terminus of SR 810 |
| Broward | Coconut Creek–Parkland line | 39.158 | 63.019 | Loxahatchee Road (CR 827) | |
| Palm Beach | ​ | 40.756 | 65.590 | Palmetto Park Road (CR 798) to I-95 / US 1 / SR A1A | Former SR 798 |
| Palm Beach | ​ | 42.022 | 67.628 | SR 808 east / CR 808 west (Glades Road) to Florida's Turnpike / I-95 | Western terminus of SR 808; Eastern terminus of CR 808 |
| Palm Beach | ​ | 43.831 | 70.539 | Yamato Road (CR 794 east) | Western terminus of CR 794 |
| Palm Beach | ​ | 47.941 | 77.154 | SR 806 east (West Atlantic Avenue) to I-95 / Florida's Turnpike | Western terminus of SR 806 |
| Palm Beach | ​ | 53.015 | 85.319 | SR 804 east (Boynton Beach Boulevard) to I-95 / Florida's Turnpike | Western terminus of SR 804 |
| Palm Beach | ​ | 57.408 | 92.389 | CR 812 east (Lantana Road) to I-95 / US 1 | Western terminus of CR 812; former SR 812 |
| Palm Beach | ​ | 59.200 | 95.273 | To SR 802 east (Lake Worth Road) / US 1 / Florida's Turnpike | Western terminus of SR 802 |
| Palm Beach | Wellington | 61.496 | 98.968 | SR 882 east (Forest Hill Boulevard) to US 1 / I-95 | Western terminus of SR 882 |
| Palm Beach | Royal Palm Beach | 63.556 | 102.283 | US 98 east / SR 80 east (Southern Boulevard) to Florida's Turnpike / I-95 – West Palm Beach SR 7 north | Interchange; south end of US 98 / SR 80 overlap; north end of SR 7 overlap |
| Palm Beach | Royal Palm Beach–Wellington line | 66.325 | 106.740 | Forest Hill Boulevard / Crestwood Boulevard | |
| Palm Beach | Twenty Mile Bend | 75.024 | 120.739 | CR 880 west | Eastern terminus of CR 880 |
| Palm Beach | ​ | 79.933 | 128.640 | SR 700 west / CR 700 east – Canal Point | Former US 98 west |
| Palm Beach | ​ | 93.270 | 150.104 | SR 15 south / SR 80 west to US 27 – Belle Glade, South Bay, Clewiston, Orlando SR 812 west (Hooker Highway) – Pahokee, Canal Point, truck bypass to South Bay | North end of SR 80 overlap; south end of SR 15 overlap |
| Palm Beach | Pahokee | 99.574 | 160.249 | SR 729 north (State Market Road) | Southern terminus of SR 729 |
| Palm Beach | Pahokee | 101.000 | 162.544 | SR 715 south (Bacom Point Road) / East First Street | Northern terminus of SR 715 |
| Palm Beach | Pahokee | 102.982 | 165.733 | SR 729 south (State Market Road) | Northern terminus of SR 729 |
| Palm Beach | Canal Point | 104.525 | 168.217 | SR 700 east – West Palm Beach | Southern terminus of concurrency with SR 700; former US 98 east |
| Martin | Port Mayaca | 112.789 | 181.516 | SR 76 east (Kanner Highway) to I-95 – Indiantown, Stuart | Western terminus of SR 76 |
| Okeechobee | ​ | 125.840 | 202.520 | CR 15B east (Southeast 126th Boulevard) to SR 710 | |
| Okeechobee | ​ | 129.291 | 208.074 | CR 15A east (Southeast 86th Boulevard) to SR 710 | |
| Okeechobee | Taylor Creek | 133.61 | 215.02 | Taylor Creek Bridge over Taylor Creek | Taylor Creek Bridge over Taylor Creek |
| Okeechobee | Okeechobee | 135.707 | 218.399 | SR 78 west – Moore Haven, Ft. Myers | Eastern terminus of SR 78 |
| Okeechobee | Okeechobee | 138.841 | 223.443 | US 98 north / SR 70 (Park Street (SR 700)) to SR 710 south / Florida's Turnpike / I-95 – Arcadia, Ft. Pierce | Northern terminus of concurrency with US 98 / SR 700 |
| Okeechobee | Okeechobee | 141.231 | 227.289 | CR 718 west (Northwest 36th Street) to US 98 | County road shields on 441 read "NW 36 ST" instead of "718"; otherwise, route is unsigned. |
| Okeechobee | ​ | 148.986 | 239.770 | CR 68 west (Northeast 160th Street) to US 98 | |
| Okeechobee | ​ | 153.071 | 246.344 | CR 68 east (Northeast 224th Street) to I-95 – Ft. Pierce | |
| Okeechobee | ​ | 154.114 | 248.022 | CR 724 west (Northwest 240th Street) | Access to Kissimmee Prairie Preserve State Park |
| Okeechobee | Fort Drum | 158.137 | 254.497 | CR 15C east (Northeast 304th Street) | Ft. Drum Cemetery |
| Osceola | Yeehaw Junction | 171.736 | 276.382 | SR 60 to Florida's Turnpike / I-95 – Lake Wales, Vero Beach | |
| Osceola | Kenansville | 185.763 | 298.957 | CR 523 north (South Canoe Creek Road) | |
| Osceola | Holopaw | 205.436 | 330.617 | US 192 east (Bronson Highway / SR 500) – Melbourne | Southern terminus of concurrency with US 192 / SR 500 |
| see US 192 (mile 42.586-18.123) ||||||
| Osceola | Kissimmee | 229.899 | 369.987 | US 17 south / US 92 west / US 192 west (Vine Street / SR 530 / SR 600) / Main Street – Downtown Kissimmee, Haines City, Amtrak/SunRail | Northern terminus of concurrency with US 192 Southern terminus of concurrency with US 17 / US 92 / SR 600 |
| Osceola | Kissimmee | 232.148 | 373.606 | CR 522 / US 17 Truck south / US 92 Truck west (Osceola Parkway) to Florida's Turnpike / I-4 – Disney World | |
| Orange | Hunter's Creek | 234.58 | 377.52 | SR 417 to I-4 – International Airport, Tampa, Disney World | Exit 11 on SR 417 |
| Orange | Sky Lake | 238.407 | 383.679 | To SR 528 west / Consulate Drive | SR 528 exit 4 |
| Orange | Sky Lake | 238.66 | 384.09 | Florida's Turnpike (SR 91) – Ocala, Miami | Turnpike exit 254 |
| Orange | Sky Lake | 238.950 | 384.553 | To SR 528 / Landstreet Road (CR 527A east) – International Airport | SR 528 exit 4 |
| Orange | Sky Lake | 239.947 | 386.157 | SR 482 (Sand Lake Road) to SR 528 – Volcano Bay, Universal, International Airport, Titusville, Cape Canaveral | |
| Orange | Orlando | 244.15 | 392.92 | I-4 (SR 400) | Exit 80 on I-4; no access from US 441 south to I-4 east or I-4 west to US 441 north |
| Orange | Holden Heights | 244.414 | 393.346 | To I-4 east / Michigan Street | |
| Orange | Orlando | 245.831 | 395.627 | SR 408 – Downtown Orlando, Titusville, Ocoee | Exit 9 on SR 408 |
| Orange | Orlando | 246.431 | 396.592 | SR 526 east (Washington Street / CR 526 west) | |
| Orange | Orlando | 247.086 | 397.646 | US 17 north / US 92 east / SR 50 (Colonial Drive / SR 600 east) to I-4 – Titusville, University of Central Florida | Northern terminus of concurrency with US 17 / US 92 / SR 600 |
| Orange | Orlando | 248.461 | 399.859 | SR 438 (Princeton Street) | |
| Orange | Orlando | 249.012 | 400.746 | SR 416 west (Silver Star Road) | |
| Orange | Orlando | 250.496 | 403.134 | SR 423 (John Young Parkway / Lee Road) to I-4 – Winter Park | |
| Orange | Lockhart | 253.85 | 408.53 | SR 414 east / SR 414 west to I-4 / SR 429 – Maitland, Apopka | SR 414 exit 9 |
| Seminole | No major junctions | No major junctions | No major junctions | No major junctions | No major junctions |
| Orange | Apopka | 257.66 | 414.66 | SR 436 east – Altamonte Springs | interchange |
| Orange | Apopka | 258.027 | 415.254 | Alabama Avenue (CR 424 east) | |
| Orange | Apopka | 258.477 | 415.978 | CR 435 (Park Avenue) | |
| Orange | Apopka | 258.608 | 416.189 | CR 437A south (Central Avenue / CR 424 west) | |
| Orange | Apopka | 259.77 | 418.06 | SR 451 south to SR 429 south / SR 414 east / Vick Road – Orlando, Maitland, Ocoee, Winter Garden, Tampa | |
| Orange | Plymouth | 261.713 | 421.186 | CR 437 north (Plymouth Sorrento Road) | south end of CR 437 overlap |
| Orange | Plymouth | 261.849 | 421.405 | CR 437 south (Orange Avenue) – Ocoee, Winter Garden | north end of CR 437 overlap |
| Orange | Apopka | 262.138 | 421.870 | To SR 429 / SR 414 east / SR 429 Connector Road – Orlando, Tampa, Maitland, Daytona Beach | |
| Orange | Zellwood | 265.773 | 427.720 | CR 448 Truck west (Jones Avenue) | |
| Orange | Tangerine | 267.327 | 430.221 | CR 448 west (Sadler Road) – Lake Jem | |
| Orange | ​ | 269.316 | 433.422 | CR 500A north – Mt. Dora | Former SR 500A |
| Lake | Mount Dora | 270.71 | 435.67 | SR 46 east (CR 46 west) – Mt. Dora, Sanford | interchange |
| Lake | Mount Dora | 273.184 | 439.647 | SR 44 east / Donnelly Street – to bypass SR 19 north, Downtown Mount Dora | former CR 44B |
| Lake | Eustis–Mount Dora line | 275.123 | 442.768 | CR 44C south (Eudora Road) | |
| Lake | Eustis | 275.77 | 443.81 | SR 19 north / CR 19A south – Eustis, Umatilla, Mt. Dora | interchange; south end of SR 19 overlap |
| Lake | Eustis | 276.066 | 444.285 | CR 19A south / Plaza Drive | |
| Lake | Tavares | 279.017 | 449.034 | SR 19 south / Orange Avenue | north end of SR 19 overlap |
| Lake | Tavares | 279.213 | 449.350 | To Lakeshore Boulevard (SR 500A) south south / SR 19 – Tavares, Business District, Mt. Dora | |
| Lake | Leesburg | 281.530 | 453.079 | CR 473 north | |
| Lake | Leesburg | 283.648 | 456.487 | CR 449 north (Stewart Lane) – Silver Lake | |
| Lake | Leesburg | 284.439 | 457.760 | CR 44 Leg A west | |
| Lake | Leesburg | 285.363 | 459.247 | CR 44 east – Lisbon | |
| Lake | Leesburg | 287.163 | 462.144 | SR 44 west (East Dixie Avenue) to US 27 south | |
| Lake | Leesburg | 289.300 | 465.583 | US 27 south (North 14th Street / SR 25) – Clermont | Southern terminus of concurrency with US 27 / SR 25 |
| Lake | Leesburg | 289.524 | 465.944 | CR 44A west (Griffin Road) | |
| Lake | Leesburg | 290.187 | 467.011 | CR 466A east (Picciola Road) | |
| Lake | Fruitland Park | 290.786 | 467.975 | CR 25A north | |
| Lake | Fruitland Park | 292.039 | 469.991 | CR 466A west (Miller Street) – Wildwood | |
| Lake | Fruitland Park | 292.502 | 470.736 | CR 25A south | |
| Lake | Lady Lake | 296.211 | 476.705 | CR 466 west | |
| Lake | Lady Lake | 296.619 | 477.362 | CR 25 north – Weirsdale | Northern terminus of concurrency with SR 25 |
| Sumter | No major junctions | No major junctions | No major junctions | No major junctions | No major junctions |
| Marion | ​ | 302.23 | 486.39 | CR 42 – Pedro, Weirsdale | |
| Marion | ​ | 306.211 | 492.799 | To I-75 / Southeast 132nd Street Road | south bypass of Belleview |
| Marion | Belleview | 307.889 | 495.499 | CR 25A east | |
| Marion | Belleview | 308.784 | 496.940 | US 301 south (SR 35) – Wildwood | Southern terminus of concurrency with US 301 |
| Marion | Belleview | 308.973 | 497.244 | SR 25 south / CR 484 west to SR 35 / I-75 – Dunnellon, Ocklawaha | Southern terminus of concurrency with SR 25; Eastern terminus of CR 484 |
| Marion | Santos | 313.206 | 504.056 | CR 328 west (Southeast 80th Street) – Santos, Santos Trailhead (Cross Florida Greenway) | |
| Marion | ​ | 316.414 | 509.219 | CR 464A (Lake Weir Avenue) | |
| Marion | Ocala | 318.130 | 511.981 | CR 475 south | |
| Marion | Ocala | 318.692 | 512.885 | SR 464 west (Southwest 17th Street) to SR 200 | |
| Marion | Ocala | 319.221 | 513.736 | SR 200 west (Southwest 10th Street) to I-75 – Hernando, Inverness, College of Central Florida | Southern terminus of concurrency with SR 200 |
| Marion | Ocala | 319.760 | 514.604 | SR 40 (West Silver Springs Boulevard) – Dunnellon, Silver Springs, Business District | |
| Marion | Ocala | 320.451 | 515.716 | US 27 north / SR 492 east (Bonnie Heath Boulevard / SR 500 north) to I-75 – Williston, Silver Springs | Northern terminus of concurrency with US 27 (and unsigned SR 500); Western terminus of SR 492 |
| Marion | Ocala | 321.097 | 516.756 | CR 200A north (Northwest 20th Street) | |
| Marion | Ocala | 321.962 | 518.148 | CR 25A north (Northwest Gainesville Road) – Lowell, Reddick | |
| Marion | ​ | 324.843 | 522.784 | SR 326 (Ocala Bypass) to I-75 / SR 40 east – Ormond Beach | |
| Marion | ​ | 327.351 | 526.820 | Northwest 100th Street - Martin, Anthony | |
| Marion | ​ | 330.246 | 531.479 | CR 329 – Lowell, Sparr | |
| Marion | ​ | 330.372 | 531.682 | US 301 north (SR 200) – Starke | Interchange; northbound exit and southbound entrance; northern terminus of concurrency with US 301 / SR 200 |
| Marion | ​ | 332.637 | 535.327 | CR 316 – Reddick, Fairfield | |
| Marion | ​ | 336.048 | 540.817 | CR 25A south (Northwest Gainesville Road) | |
| Marion | ​ | 336.680 | 541.834 | CR 318 to I-75 – Irvine, Citra | |
| Marion | McIntosh | 339.422 | 546.247 | CR 320 west (Avenue G) | |
| Marion–Alachua county line | ​ | 342.413 | 551.060 | Southeast 185th Avenue / Northwest 320th Street - Evinston | |
| Alachua | ​ | 344.139 | 553.838 | Southeast 165th Avenue - Micanopy | |
| Alachua | Micanopy | 344.432 | 554.310 | CR 346 east – Cross Creek | |
| Alachua | Micanopy | 345.321 | 555.740 | CR 234 east / Southeast Cholokka Boulevard – Historic Micanopy, Museum | |
| Alachua | ​ | 345.987 | 556.812 | CR 234 west to I-75 – Micanopy | |
| Alachua | ​ | 354.041 | 569.774 | SR 331 (Southwest Williston Road) to SR 329 / I-75 – Williston, Waldo, truck route to SR 121 north / US 441 north | |
| Alachua | Gainesville | 355.538 | 572.183 | SR 226 / SR 24A (Southwest 16th Avenue) to I-75 | |
| Alachua | Gainesville | 355.917 | 572.793 | SR 24 west (Archer Road) – University Medical Center, VA Hospital | Southern terminus of concurrency with SR 24 |
| Alachua | Gainesville | 356.616 | 573.918 | SR 24 east / SR 26 (West University Avenue) to I-75 | Northern terminus of concurrency with SR 24 |
| Alachua | Gainesville | 358.127 | 576.350 | SR 120 east (Northwest 23rd Avenue) | |
| Alachua | Gainesville | 359.131 | 577.965 | SR 222 (Northwest 39th Avenue) to I-75 – truck route to SR 121 south / US 441 south | |
| Alachua | Gainesville | 359.884 | 579.177 | SR 20 east (Northwest 6th Street) | Southern terminus of concurrency with SR 20 |
| Alachua | Gainesville | 360.243 | 579.755 | CR 232 (Northwest 53rd Avenue) | |
| Alachua | Gainesville | 361.105 | 581.142 | SR 121 (Northwest 22nd Street) – Williston, LaCrosse | |
| Alachua | Alachua | 365.792 | 588.685 | CR 25A north (Northwest 120th Lane) | |
| Alachua | Alachua | 366.837 | 590.367 | CR 237 north – Hague | |
| Alachua | Alachua | 367.229 | 590.998 | CR 25A south (Northwest 126th Avenue) | |
| Alachua | Alachua | 369.549 | 594.731 | CR 2054 west (Rachael Boulevard) | |
| Alachua | Alachua | 371.674 | 598.151 | SR 235 (Northwest 140th Street) – Newberry, LaCrosse | |
| Alachua | Alachua | 373.01 | 600.30 | I-75 (SR 93) – Tampa, Lake City | Exit 399 on I-75 |
| Alachua | Alachua | 373.788 | 601.553 | CR 235A (Northwest 173rd Street) | |
| Alachua | High Springs | 377.744 | 607.920 | SR 20 west (Northeast 1st Avenue) to US 27 – Ft. White, Ichetucknee Springs State Park, Downtown High Springs | Northern terminus of concurrency with SR 20 |
| Alachua | High Springs | 378.366 | 608.921 | US 41 south / CR 236 east (North Main Street / SR 45) to US 27 – Newberry, Santa Fe, Downtown High Springs | Southern terminus of concurrency with US 41; Northern terminus of SR 45 |
| see US 41 (mile 408.870-431.599) ||||||
| Columbia | ​ | 401.095 | 645.500 | US 41 north / US 441 Truck north (SR 25) | Northern terminus of concurrency with US 41 / SR 25 Southern terminus of SR 25A |
| Columbia | Lake City | 403.630 | 649.580 | SR 10A (Baya Drive) | |
| Columbia | Lake City | 404.065 | 650.280 | US 90 (Duval Street / SR 10 / SR 47 south / SR 100 east) to SR 100 | south end of SR 47 / SR 100 overlap |
| Columbia | Lake City | 405.034 | 651.839 | US 441 Truck south (Bascom Norris Drive / CR 100A / truck route to US 90 / SR 100 east) | |
| Columbia | Five Points | 405.441 | 652.494 | CR 25A north / Gum Swamp Road (CR 250 east) | north end of SR 25A overlap |
| Columbia | Lake City | 407.67 | 656.08 | I-10 (SR 8) – Live Oak, Jacksonville | Exit 303 on I-10 |
| Columbia | ​ | 412.896 | 664.492 | CR 246 west (Northwest Lassie Black Street) | |
| Columbia | ​ | 427.417 | 687.861 | CR 6 west – Jasper | |
| Columbia | ​ | 433.050 | 696.926 | US 441 north / SR 89 north – Fargo, Homerville | Georgia state line |
| 1.000 mi = 1.609 km; 1.000 km = 0.621 mi Concurrency terminus Incomplete access ||||||

## Related routes

At least six other special routes of US 441 have existed in Florida, however only two exist today.
* U.S. Route 441 Business – Tangerine to Tavares; former Mount Dora Business route, now County Road Old 441. In Mt. Dora and Tavares, former SR S-500A.
* U.S. Route 441 Alternate – Lady Lake to Belleview; former route co-signed with Alternate U.S. Route 27.
* U.S. Route 441 Alternate – Ocala to Reddick; Today CR 25A.
* U.S. Route 441 Truck – Gainesville
* U.S. Route 441 Truck – Lake City

## In popular culture

Route 441 is mentioned in the song "American Girl" by Tom Petty and the Heartbreakers. Petty was a native of Gainesville.