# Mississippi Highway 322

Mississippi Highway 322 (MS 322) is an east-west state highway connecting Sherard at MS 1 to Crowder at MS 35. Traveling through Coahoma, Quitman, Panola counties, it has a length of 43.9 miles (70.7 km) and connects Clarksdale, Hopson, Lambert, and Crowder.

## Route description

MS 322 begins in the unincorporated community of Sherard at MS 1. The highway heads due east and enters the city limits of Clarksdale, but travels to the west and south of the downtown area. In the city, it carries the name Sherard Road. Within the city, MS 322 travels mostly past commercial and light industrial businesses. At MS 161, MS 322 turns to the southwest to form a concurrency with it for just over one mile (1.6 km). At the southwest corner of Clarksdale, MS 161 ends at an intersection with U.S. Route 61 (US 61) and US 278 however MS 322 continues along US 61 and US 278 along its freeway bypass of Clarksdale. MS 322 exits the freeway at the interchange with US 49 and then runs concurrent with it to the southeast for about one-half mile (0.80 km) in the community of Hopson. An independent route again, the roadway heads east through agricultural fields and leaves Coahoma County for Quitman County.
After continuing east through farmlands in Quitman County for 8.5 miles (13.7 km), MS 322 reaches an intersection with MS 3. The two routes head north and enter the town of Lambert. At Scott Avenue, MS 322 leaves the concurrency and heads east, crossing a railroad and intersecting MS 321. At first, the highway heads due east, but then takes a more curvy path around bayous, Little Tallahatchie River, and Old Yocona River. MS 322 enters the town of Crowder on 3rd Street. Near the center of town, MS 322 takes a one-block jog north on Quitman Avenue before resuming an easterly course on 2nd Street. MS 322 heads into Panola County, still within the town of Crowder, heading in a general eastern direction, again crossing the Little Tallahatchie River, and ends at MS 35.
Except along its concurrencies with U.S. highways around Clarksdale, the entire road is two lanes wide and is fully state-maintained.

## Major intersections

| County | Location | mi | km | Destinations | Notes |
| Coahoma | Sherard | 0.000 | 0.000 | MS 1 – Rosedale, Greenville, Friars Point | Western terminus |
| Coahoma | Clarksdale | 7.444 | 11.980 | MS 161 north (South State Street) – Clarksdale | Western end of MS 161 concurrency |
| Coahoma | Clarksdale | 8.633 | 13.893 | US 61 south / US 278 west / MS 161 ends – Cleveland | Western end of US 61 / US 278 concurrency; eastern end of MS 161 concurrency; southern terminus of MS 161 |
| Coahoma | Clarksdale | 9.637– 10.078 | 15.509– 16.219 | New Africa Road - Downtown Clarksdale | Interchange |
| Coahoma | Clarksdale | 11.944– 12.340 | 19.222– 19.859 | US 49 north / US 61 north / US 278 east / MS 149 north (Desoto Avenue) – Clarksdale, Helena-West Helena, Memphis, Delta Blues Museum | Interchange; eastern end of US 61 / US 278 concurrency; western end of US 49 concurrency; southern terminus of MS 149 |
| Coahoma | Clarksdale | 12.899 | 20.759 | US 49 south (Hopson Pixley Road) – Greenwood, Indianola | Eastern end of US 49 concurrency |
| Quitman | ​ | 27.011 | 43.470 | MS 3 south | Western end of MS 3 concurrency |
| Quitman | Lambert | 30.213 | 48.623 | MS 3 north (10th Street) / Scott Avenue | Eastern end of MS 3 concurrency |
| Quitman | Lambert | 30.500 | 49.085 | MS 321 south (6th Street) – O'Keefe WMA | Northern terminus of MS 321 |
| Panola | ​ | 43.859 | 70.584 | MS 35 | Eastern terminus |
| 1.000 mi = 1.609 km; 1.000 km = 0.621 mi Concurrency terminus ||||||