# 2022 National Premier Soccer League season

The 2022 National Premier Soccer League season was the 20th season of the National Premier Soccer League and part of the 110th season of FIFA-sanctioned soccer in the United States.
The regular season began on March 19 and ended on July 16. In total, 92 teams participated in this season.

## Format changes

The Northwest and Southwest Conferences merged to form the Pacific Conference while the Golden Gate Conference returned to traditional league play. The Lone Star Conference returned to the South Region after temporarily joining the West in 2021.

## Teams

Note: Teams that are italicized previously played in the NPSL and are returning from hiatus.

### Incoming teams

* Akron City FC (Akron, OH)
* Apotheos FC (Kennesaw, GA)
* Austin United FC (Austin, TX)
* Cedar Stars FC (Chester, NY)
* Club Atletico Saint Louis (Saint Louis, MO)
* Corinthians FC of San Antonio (San Antonio, TX)
* Grove Soccer United (Richmond, VA)
* Jackson Lions FC (Jackson, NJ)
* Lubbock Matadors SC (Lubbock, TX)
* Magia FC (Miami Gardens, FL)
* Miami Beach CF (Miami Beach, FL)
* Minnesota TwinStars FC (Brooklyn Park, MN)
* Muskegon Risers SC (Muskegon, MI)
* Oakland SC (Oakland, CA)
* Pennsylvania Classics AC (Lancaster, PA)
* Philadelphia Ukrainians Nationals SC (Horsham, PA)
* SC Brave Lions (Glendale, CA)
* Sunflower State FC (Overland Park, KS)

### Name changes

* Greater Lowell Rough Diamonds to Alexandria Reds
* Katy 1895 FC to CF10 Houston FC

### Departing teams

* ASC San Diego (San Diego, CA) (merged with San Diego 1904 FC and joined the National Independent Soccer Association)
* Boston City FC (Revere, MA) (joined USL League Two)
* FC Baltimore Christos (Baltimore, MD)
* Metro Louisville FC (Louisville, KY) (joined United Premier Soccer League)
* PDX FC (Portland, OR) (joined USL League Two in 2021)
* Rochester Lancers (Rochester, NY) (joined United Premier Soccer League)

### Teams on hiatus or folded

* Boca Raton FC (Delray Beach, FL)
* Dallas City FC (McKinney, TX)
* FC Golden State (Pomona, CA)
* FC Indiana (Lafayette, IN)
* Midland-Odessa Sockers FC (Midland, TX)
* Port City FC (Gulfport, MS)
* Spokane Shadow SC (Spokane, WA)
* Storm FC (Pembroke Pines, FL)
* Tacoma Stars (Waller, WA)
* Temecula FC (Temecula, CA)

### 2022 Teams

West Region :
| Division | Team |
| Golden Gate Conference | Academica SC |
| Golden Gate Conference | Contra Costa FC |
| Golden Gate Conference | El Farolito |
| Golden Gate Conference | FC Davis |
| Golden Gate Conference | Napa Valley 1839 FC |
| Golden Gate Conference | Oakland SC |
| Golden Gate Conference | Oakland Stompers |
| Golden Gate Conference | Sacramento Gold FC |
| Golden Gate Conference | Sonoma County Sol |
| Pacific Conference | Crossfire Redmond |
| Pacific Conference | FC Arizona |
| Pacific Conference | International Portland Select FC |
| Pacific Conference | Las Vegas Legends FC |
| Pacific Conference | OSA Seattle FC |
| Pacific Conference | SC Brave Lions |
South Region :
| Division | Team |
| Gulf Coast Conference | AFC Mobile |
| Gulf Coast Conference | Florida Roots Futbol Club |
| Gulf Coast Conference | Jacksonville Armada U-23 |
| Gulf Coast Conference | New Orleans Jesters |
| Gulf Coast Conference | Pensacola FC |
| Gulf Coast Conference | Southern States SC |
| Gulf Coast Conference | Tallahassee SC |
| Heartland Conference | Arkansas Wolves FC |
| Heartland Conference | Club Atletico Saint Louis |
| Heartland Conference | Demize NPSL |
| Heartland Conference | OKC 1889 FC |
| Heartland Conference | Sunflower State FC |
| Heartland Conference | Reign FK |
| Heartland Conference | Tulsa Athletic |
| Lone Star Conference | Austin United FC |
| Lone Star Conference | CF10 Houston FC |
| Lone Star Conference | Corinthians FC of San Antonio |
| Lone Star Conference | Coyotes FC |
| Lone Star Conference | Denton Diablos FC |
| Lone Star Conference | FC Brownsville |
| Lone Star Conference | Fort Worth Vaqueros FC |
| Lone Star Conference | Irving FC |
| Lone Star Conference | Laredo Heat SC |
| Lone Star Conference | Lubbock Matadors SC |
| Sunshine Conference | Central Florida Panthers SC |
| Sunshine Conference | Magia FC |
| Sunshine Conference | Miami Beach CF |
| Sunshine Conference | Miami Dutch Lions FC |
| Sunshine Conference | Miami United FC |
| Sunshine Conference | Naples United FC |
Midwest Region :
| Division | Team |
| Great Lakes Conference | Carpathia FC |
| Great Lakes Conference | FC Columbus |
| Great Lakes Conference | Milwaukee Torrent |
| Great Lakes Conference | Muskegon Risers SC |
| Great Lakes Conference | Panathinaikos Chicago |
| North Conference | Dakota Fusion FC |
| North Conference | Duluth FC |
| North Conference | Joy St. Louis Park |
| North Conference | LaCrosse Aris FC |
| North Conference | Med City FC |
| North Conference | Minneapolis City SC |
| North Conference | Minnesota Twin Stars |
| North Conference | Sioux Falls Thunder FC |
| Rust Belt Conference | Akron City FC |
| Rust Belt Conference | Cleveland SC |
| Rust Belt Conference | Erie Commodores FC |
| Rust Belt Conference | FC Buffalo |
| Rust Belt Conference | Pittsburgh Hotspurs |
East Region :
| Division | Team |
| Keystone Conference | Atlantic City FC |
| Keystone Conference | Electric City Shock SC |
| Keystone Conference | FC Monmouth |
| Keystone Conference | FC Motown |
| Keystone Conference | Hershey FC |
| Keystone Conference | Jackson Lions FC |
| Keystone Conference | Pennsylvania Classics AC |
| Keystone Conference | Philadelphia Lone Star FC |
| Keystone Conference | Philadelphia Ukrainians Nationals |
| Keystone Conference | Torch FC |
| Keystone Conference | West Chester United SC |
| Mid-Atlantic Conference | Alexandria Reds |
| Mid-Atlantic Conference | FC Frederick |
| Mid-Atlantic Conference | First State FC |
| Mid-Atlantic Conference | Grove Soccer United |
| Mid-Atlantic Conference | Northern Virginia United FC |
| Mid-Atlantic Conference | Virginia Beach City FC |
| North Atlantic Conference | Cedar Stars FC |
| North Atlantic Conference | Hartford City FC |
| North Atlantic Conference | Kingston Stockade FC |
| North Atlantic Conference | New York Shockers |
| North Atlantic Conference | Syracuse FC |
| North Atlantic Conference | Valeo FC |
| Southeast Conference | Apotheos FC |
| Southeast Conference | Appalachian FC |
| Southeast Conference | Georgia Revolution FC |
| Southeast Conference | Georgia Storm |
| Southeast Conference | LSA Athletico Lanier |
| Southeast Conference | North Alabama SC |

## Standings and results
### West Region
#### Golden Gate Conference

| Pos | Team | Pld | W | L | T | GF | GA | GD | Pts | Qualification |
| 1 | Sacramento Gold | 10 | 8 | 1 | 1 | 29 | 12 | +17 | 25 | Golden Gate Conference playoffs |
| 2 | El Farolito | 10 | 8 | 2 | 0 | 38 | 11 | +27 | 24 | Golden Gate Conference playoffs |
| 3 | Napa Valley 1839 FC | 10 | 8 | 2 | 0 | 32 | 11 | +21 | 24 | Golden Gate Conference playoffs |
| 4 | Contra Costa FC | 10 | 4 | 5 | 1 | 28 | 25 | +3 | 13 | Golden Gate Conference playoffs |
| 5 | Academica SC | 10 | 4 | 5 | 1 | 19 | 18 | +1 | 13 | Golden Gate Conference playoffs |
| 6 | FC Davis | 10 | 4 | 5 | 1 | 16 | 27 | −11 | 13 | Golden Gate Conference playoffs |
| 7 | Oakland SC | 10 | 3 | 5 | 2 | 19 | 28 | −9 | 11 | Golden Gate Conference playoffs |
| 8 | Sonoma County Sol | 10 | 2 | 8 | 0 | 14 | 37 | −23 | 6 | Golden Gate Conference playoffs |
| 9 | Oakland Stompers | 10 | 0 | 8 | 2 | 10 | 36 | −26 | 2 | |

#### Pacific Conference

Due to the distance between teams, the Pacific Conference was split into two divisions. The North Division featured Crossfire Redmond, International Portland Select FC and OSA Seattle FC while the South Division included FC Arizona, Las Vegas Legends FC, and SC Brave Lions. Clubs played the other teams within their division three times each and two of the teams in the other division twice each. The top two teams from each group qualified for the playoffs and play one-another in the conference semifinals.

##### North Division

| Pos | Team | Pld | W | L | T | GF | GA | GD | Pts | Qualification |
| 1 | International Portland Select FC | 10 | 6 | 1 | 3 | 24 | 6 | +18 | 21 | North Division playoffs |
| 2 | Crossfire Redmond | 10 | 4 | 1 | 5 | 16 | 10 | +6 | 17 | North Division playoffs |
| 3 | OSA Seattle FC | 10 | 1 | 8 | 1 | 7 | 29 | −22 | 4 | |

##### South Division

| Pos | Team | Pld | W | L | T | GF | GA | GD | Pts | Qualification |
| 1 | SC Brave Lions | 10 | 7 | 3 | 0 | 24 | 14 | +10 | 21 | South Division playoffs |
| 2 | FC Arizona | 10 | 2 | 4 | 4 | 13 | 21 | −8 | 10 | South Division playoffs |
| 3 | Las Vegas Legends FC | 10 | 2 | 5 | 3 | 20 | 24 | −4 | 9 | |

### Midwest Region
#### Great Lakes Conference

| Pos | Team | Pld | W | L | T | GF | GA | GD | Pts | Qualification |
| 1 | Muskegon Risers (C) | 10 | 8 | 0 | 2 | 33 | 10 | +23 | 26 | Midwest Region Semifinals |
| 2 | FC Columbus | 10 | 6 | 2 | 2 | 31 | 18 | +13 | 20 | Midwest Region Quarterfinals |
| 3 | Carpathia FC | 10 | 3 | 4 | 3 | 15 | 20 | −5 | 12 | |
| 4 | Milwaukee Torrent | 10 | 2 | 6 | 2 | 20 | 22 | −2 | 8 | |
| 5 | Panathinaikos Chicago | 10 | 1 | 8 | 1 | 8 | 37 | −29 | 4 | |

#### North Conference

| Pos | Team | Pld | W | L | T | GF | GA | GD | Pts | Qualification |
| 1 | Med City FC (C) | 14 | 11 | 1 | 2 | 35 | 11 | +24 | 35 | Midwest Region Semifinals |
| 2 | Duluth FC | 14 | 11 | 2 | 1 | 43 | 12 | +31 | 34 | Midwest Region Quarterfinals |
| 3 | Dakota Fusion FC | 14 | 7 | 4 | 3 | 36 | 28 | +8 | 24 | |
| 4 | Minneapolis City SC | 14 | 7 | 6 | 1 | 29 | 27 | +2 | 22 | |
| 5 | Sioux Falls Thunder FC | 14 | 3 | 6 | 5 | 27 | 28 | −1 | 14 | |
| 6 | Minnesota TwinStars FC | 14 | 4 | 9 | 1 | 22 | 42 | −20 | 13 | |
| 7 | Joy St. Louis Park | 14 | 3 | 10 | 1 | 15 | 36 | −21 | 10 | |
| 8 | La Crosse Aris FC | 14 | 3 | 11 | 0 | 21 | 44 | −23 | 9 | |

#### Rust Belt Conference

| Pos | Team | Pld | W | L | T | GF | GA | GD | Pts | Qualification |
| 1 | Cleveland SC (C) | 12 | 8 | 3 | 1 | 33 | 14 | +19 | 25 | Midwest Region Quarterfinals |
| 2 | Pittsburgh Hotspurs | 12 | 8 | 4 | 0 | 24 | 15 | +9 | 24 | Midwest Region Quarterfinals |
| 3 | FC Buffalo | 12 | 5 | 6 | 1 | 15 | 20 | −5 | 16 | |
| 4 | Erie Commodores | 12 | 3 | 7 | 2 | 13 | 23 | −10 | 11 | |
| 5 | Akron City FC | 12 | 2 | 6 | 4 | 10 | 23 | −13 | 10 | |

### South Region
#### Gulf Coast Conference

| Pos | Team | Pld | W | L | T | GF | GA | GD | Pts | Qualification |
| 1 | Jacksonville Armada FC U-23 | 12 | 11 | 0 | 1 | 36 | 11 | +25 | 34 | Gulf Coast Conference playoffs |
| 2 | Southern States SC | 12 | 9 | 3 | 0 | 35 | 14 | +21 | 27 | Gulf Coast Conference playoffs |
| 3 | New Orleans Jesters | 12 | 6 | 5 | 1 | 28 | 24 | +4 | 19 | Gulf Coast Conference playoffs |
| 4 | Pensacola FC | 12 | 6 | 5 | 1 | 21 | 23 | −2 | 19 | Gulf Coast Conference playoffs |
| 5 | AFC Mobile | 12 | 4 | 7 | 1 | 19 | 20 | −1 | 13 | |
| 6 | Florida Roots FC | 12 | 3 | 9 | 0 | 18 | 39 | −21 | 9 | |
| 7 | Tallahassee SC | 12 | 0 | 10 | 2 | 12 | 38 | −26 | 2 | |

#### Heartland Conference

| Pos | Team | Pld | W | L | T | GF | GA | GD | Pts | Qualification |
| 1 | Tulsa Athletic | 12 | 9 | 1 | 2 | 36 | 10 | +26 | 29 | Heartland Conference playoffs |
| 2 | OKC 1889 FC | 12 | 8 | 2 | 2 | 20 | 14 | +6 | 26 | Heartland Conference playoffs |
| 3 | Sunflower State FC | 12 | 5 | 4 | 3 | 19 | 20 | −1 | 18 | Heartland Conference playoffs |
| 4 | Demize NPSL | 12 | 4 | 4 | 4 | 18 | 20 | −2 | 16 | Heartland Conference playoffs |
| 5 | Arkansas Wolves FC | 12 | 4 | 7 | 1 | 18 | 21 | −3 | 13 | |
| 6 | Club Atletico Saint Louis | 12 | 4 | 8 | 0 | 18 | 29 | −11 | 12 | |
| 7 | Reign FK | 12 | 1 | 9 | 2 | 12 | 27 | −15 | 5 | |

#### Lone Star Conference

| Pos | Team | Pld | W | L | T | GF | GA | GD | Pts | Qualification |
| 1 | Laredo Heat SC | 12 | 8 | 1 | 3 | 30 | 8 | +22 | 27 | Lone Star Conference playoffs |
| 2 | FC Brownsville | 12 | 8 | 3 | 1 | 38 | 15 | +23 | 25 | Lone Star Conference playoffs |
| 3 | Corinthians FC of San Antonio | 12 | 7 | 2 | 3 | 29 | 20 | +9 | 24 | Lone Star Conference playoffs |
| 4 | Irving FC | 12 | 6 | 1 | 5 | 31 | 11 | +20 | 23 | Lone Star Conference playoffs |
| 5 | Denton Diablos FC | 12 | 7 | 4 | 1 | 31 | 15 | +16 | 22 | |
| 6 | Lubbock Matadors SC | 12 | 6 | 4 | 2 | 25 | 15 | +10 | 20 | |
| 7 | CF10 Houston FC | 12 | 3 | 7 | 2 | 15 | 38 | −23 | 11 | |
| 8 | Fort Worth Vaqueros FC | 12 | 3 | 8 | 1 | 17 | 25 | −8 | 10 | |
| 9 | Austin United FC | 12 | 1 | 10 | 1 | 16 | 44 | −28 | 4 | |
| 10 | Coyotes FC | 12 | 1 | 10 | 1 | 9 | 50 | −41 | 4 | |

#### Sunshine Conference

| Pos | Team | Pld | W | L | T | GF | GA | GD | Pts | Qualification |
| 1 | Miami Beach Club de Futbol | 10 | 8 | 2 | 0 | 25 | 8 | +17 | 24 | Sunshine Conference playoffs |
| 2 | Miami United FC | 10 | 7 | 3 | 0 | 26 | 10 | +16 | 21 | Sunshine Conference playoffs |
| 3 | Central Florida Panthers SC | 10 | 7 | 3 | 0 | 25 | 12 | +13 | 21 | Sunshine Conference playoffs |
| 4 | Naples United FC | 10 | 4 | 4 | 2 | 22 | 11 | +11 | 14 | Sunshine Conference playoffs |
| 5 | Miami Dutch Lions FC | 10 | 1 | 7 | 2 | 8 | 23 | −15 | 5 | |
| 6 | Magia FC | 10 | 1 | 9 | 0 | 7 | 49 | −42 | 3 | |

### East Region
#### Keystone Conference

| Pos | Team | Pld | W | L | T | GF | GA | GD | Pts | Qualification |
| 1 | FC Motown | 10 | 7 | 1 | 2 | 32 | 13 | +19 | 23 | Keystone Conference playoffs |
| 2 | Electric City Shock SC | 10 | 7 | 1 | 2 | 29 | 10 | +19 | 23 | Keystone Conference playoffs |
| 3 | West Chester United SC | 10 | 6 | 1 | 3 | 26 | 13 | +13 | 21 | Keystone Conference playoffs |
| 4 | Philadelphia Ukrainians Nationals SC | 10 | 6 | 1 | 3 | 22 | 14 | +8 | 21 | Keystone Conference playoffs |
| 5 | Jackson Lions FC | 10 | 5 | 4 | 1 | 32 | 23 | +9 | 16 | |
| 6 | Philadelphia Lone Star FC | 10 | 3 | 6 | 1 | 23 | 29 | −6 | 10 | |
| 7 | Torch FC | 10 | 3 | 6 | 1 | 14 | 24 | −10 | 10 | |
| 8 | FC Monmouth | 10 | 1 | 4 | 5 | 10 | 19 | −9 | 8 | |
| 9 | Atlantic City FC | 10 | 2 | 6 | 2 | 11 | 24 | −13 | 8 | |
| 10 | Pennsylvania Classics AC | 10 | 2 | 7 | 1 | 15 | 27 | −12 | 7 | |
| 11 | Hershey FC | 10 | 1 | 6 | 3 | 9 | 27 | −18 | 6 | |

#### Mid-Atlantic Conference

| Pos | Team | Pld | W | L | T | GF | GA | GD | Pts | Qualification |
| 1 | Alexandria Reds | 10 | 7 | 2 | 1 | 20 | 10 | +10 | 22 | Mid-Atlantic Conference playoffs |
| 2 | Northern Virginia United FC | 10 | 6 | 2 | 2 | 20 | 13 | +7 | 20 | Mid-Atlantic Conference playoffs |
| 3 | Virginia Beach City FC | 10 | 5 | 1 | 4 | 18 | 11 | +7 | 19 | Mid-Atlantic Conference playoffs |
| 4 | FC Frederick | 10 | 4 | 5 | 1 | 18 | 18 | 0 | 13 | Mid-Atlantic Conference playoffs |
| 5 | Grove Soccer United | 10 | 2 | 8 | 0 | 5 | 20 | −15 | 6 | |
| 6 | First State FC | 10 | 1 | 7 | 2 | 16 | 25 | −9 | 5 | |

#### North Atlantic Conference

| Pos | Team | Pld | W | L | T | GF | GA | GD | Pts | Qualification |
| 1 | Hartford City FC | 10 | 8 | 0 | 2 | 21 | 8 | +13 | 26 | North Atlantic Conference playoffs |
| 2 | Valeo FC | 10 | 5 | 2 | 3 | 19 | 13 | +6 | 18 | North Atlantic Conference playoffs |
| 3 | Cedar Stars FC | 10 | 2 | 3 | 5 | 12 | 18 | −6 | 11 | North Atlantic Conference playoffs |
| 4 | New York Shockers | 10 | 2 | 4 | 4 | 16 | 16 | 0 | 10 | North Atlantic Conference playoffs |
| 5 | Kingston Stockade FC | 10 | 2 | 5 | 3 | 11 | 15 | −4 | 9 | |
| 6 | Syracuse FC | 10 | 0 | 5 | 5 | 8 | 17 | −9 | 5 | |

#### Southeast Conference

| Pos | Team | Pld | W | L | T | GF | GA | GD | Pts | Qualification |
| 1 | Appalachian FC | 10 | 6 | 1 | 3 | 25 | 12 | +13 | 21 | Southeast Conference playoffs |
| 2 | Georgia Revolution FC | 10 | 4 | 2 | 4 | 26 | 12 | +14 | 16 | Southeast Conference playoffs |
| 3 | North Alabama SC | 10 | 4 | 3 | 3 | 16 | 15 | +1 | 15 | Southeast Conference playoffs |
| 4 | Apotheos FC | 10 | 3 | 2 | 5 | 13 | 10 | +3 | 14 | Southeast Conference playoffs |
| 5 | LSA Athletico Lanier | 10 | 2 | 6 | 2 | 7 | 27 | −20 | 8 | |
| 6 | Georgia Storm | 10 | 2 | 7 | 1 | 14 | 25 | −11 | 7 | |

## Playoffs

Note: Games are hosted by the highest seed unless noted otherwise

### West Region Conference playoffs
#### Golden Gate Conference playoffs

| Quarterinals June 25–26 | Quarterinals June 25–26 | Quarterinals June 25–26 | Semifinal July 9 | Semifinal July 9 | Semifinal July 9 | Final July 16 | Final July 16 | Final July 16 |
| 1 | Sacramento Gold FC | 3 | | | | | | |
| 8 | Sonoma County Sol | 1 | | | | | | |
| 8 | Sonoma County Sol | 1 | 1 | Sacramento Gold FC | 4 | | | |
| | | | 5 | Academica SC | 2 | | | |
| 4 | Contra Costa FC | 1 | 5 | Academica SC | 2 | | | |
| 5 | Academica SC | 3 | | | | | | |
| 5 | Academica SC | 3 | | | | 1 | Sacramento Gold FC | 0 |
| | | | | | | 2 | El Farolito | 3 |
| 2 | El Farolito | 5 | | | | | | | 2 | El Farolito | 3 |
| 7 | Oakland SC | 2 | | | | | | |
| 7 | Oakland SC | 2 | 2 | El Farolito | 5 | | | |
| | | | 3 | Napa Valley 1839 FC | 1 | | | |
| 3 | Napa Valley 1839 FC | 2* | 3 | Napa Valley 1839 FC | 1 | | | |
| 6 | FC Davis | 1 | | | | | | |
Bold = winner * = after extra time, ( ) = penalty shootout score

#### Pacific Conference playoffs

| Semifinals July 9–10 | Semifinals July 9–10 | Semifinals July 9–10 | Final July 16 | Final July 16 | Final July 16 |
| N1 | Int. Portland Select FC | 2 | | | |
| N2 | Crossfire Redmond | 3* | | | |
| N2 | Crossfire Redmond | 3* | N2 | Crossfire Redmond | 4 |
| | | | S2 | FC Arizona | 0 |
| S1 | SC Brave Lions | 2 | S2 | FC Arizona | 0 |
| S2 | FC Arizona | 3 | | | |
Bold = winner * = after extra time, ( ) = penalty shootout score

### South Region Conference playoffs
#### Gulf Coast Conference playoffs

| Semifinals July 13–15 | Semifinals July 13–15 | Semifinals July 13–15 | Final July 17 | Final July 17 | Final July 17 |
| 1 | JAX Armada U23 | 7 | | | |
| 4 | Pensacola FC | 2 | | | |
| 4 | Pensacola FC | 2 | 1 | JAX Armada U23 | 3 |
| | | | 2 | Southern States SC | 2 |
| 2 | Southern States SC | 5 | 2 | Southern States SC | 2 |
| 3 | New Orleans Jesters | 4 | | | |
Bold = winner * = after extra time, ( ) = penalty shootout score

#### Heartland Conference playoffs

| Semifinals July 13 | Semifinals July 13 | Semifinals July 13 | Final July 16 | Final July 16 | Final July 16 |
| 1 | Tulsa Athletic | 0(4) | | | |
| 4 | Demize NPSL | 0(2) | | | |
| 4 | Demize NPSL | 0(2) | 1 | Tulsa Athletic | 5 |
| | | | 2 | OKC 1889 FC | 1 |
| 2 | OKC 1889 FC | 4 | 2 | OKC 1889 FC | 1 |
| 3 | Sunflower State FC | 2 | | | |
Bold = winner * = after extra time, ( ) = penalty shootout score

#### Lone Star Conference playoffs

| Semifinals July 12 | Semifinals July 12 | Semifinals July 12 | Final July 16 | Final July 16 | Final July 16 |
| 1 | Laredo Heat SC | 0(3) | | | |
| 4 | Irving FC | 0(1) | | | |
| 4 | Irving FC | 0(1) | 1 | Laredo Heat SC | 3 |
| | | | 3 | Corinthians FC of SA | 0 |
| 2 | FC Brownsville | 2(4) | 3 | Corinthians FC of SA | 0 |
| 3 | Corinthians FC of SA | 2(5) | | | |
Bold = winner * = after extra time, ( ) = penalty shootout score

#### Sunshine Conference playoffs

| Semifinals July 13–15 | Semifinals July 13–15 | Semifinals July 13–15 | Final July 17 | Final July 17 | Final July 17 |
| 1 | Miami Beach CF | 2(2) | | | |
| 4 | Naples United FC | 2(3) | | | |
| 4 | Naples United FC | 2(3) | 4 | Naples United FC | 1 |
| | | | 3 | CF Panthers SC | 0 |
| 2 | Miami United FC | 1(2) | 3 | CF Panthers SC | 0 |
| 3 | CF Panthers SC | 1(4) | | | |
Bold = winner * = after extra time, ( ) = penalty shootout score
* ^ $^B$ Miami United FC was stripped of its playoff hosting privileges due to an incident in the June 29 match against Central Florida Panthers SC. Instead, #2 seed Miami played at #3 Central Florida's home venue at Lake Brantley High School.

### East Region Conference playoffs
#### Keystone Conference playoffs

| Semifinals July 15 | Semifinals July 15 | Semifinals July 15 | Final July 17 | Final July 17 | Final July 17 |
| 1 | FC Motown | 2 | | | |
| 4 | Philly Ukrainian Nationals | 0 | | | |
| 4 | Philly Ukrainian Nationals | 0 | 1 | FC Motown | 2(4) |
| | | | 3 | West Chester United | 2(2) |
| 2 | Electric City Shock SC | 1 | 3 | West Chester United | 2(2) |
| 3 | West Chester United | 3 | | | |
Bold = winner * = after extra time, ( ) = penalty shootout score

#### Mid-Atlantic Conference playoffs

| Semifinals July 13 | Semifinals July 13 | Semifinals July 13 | Final July 16 | Final July 16 | Final July 16 |
| 1 | Alexandria Reds | 3 | | | |
| 4 | FC Frederick | 1 | | | |
| 4 | FC Frederick | 1 | 1 | Alexandria Reds | 6 |
| | | | 2 | N. Virginia United FC | 5 |
| 2 | N. Virginia United FC | 4 | 2 | N. Virginia United FC | 5 |
| 3 | Virginia Beach City FC | 1 | | | |
Bold = winner * = after extra time, ( ) = penalty shootout score

#### North Atlantic Conference playoffs

| Semifinals July 13 | Semifinals July 13 | Semifinals July 13 | Final July 16 | Final July 16 | Final July 16 |
| 1 | Hartford City FC | 0 | | | |
| 4 | New York Shockers | 2 | | | |
| 4 | New York Shockers | 2 | 4 | New York Shockers | 1* |
| | | | 3 | Cedar Stars FC | 0 |
| 2 | Valeo FC | 1 | 3 | Cedar Stars FC | 0 |
| 3 | Cedar Stars FC | 2 | | | |
Bold = winner * = after extra time, ( ) = penalty shootout score

#### Southeast Conference playoffs

| Semifinals July 13 | Semifinals July 13 | Semifinals July 13 | Final July 16 | Final July 16 | Final July 16 |
| 1 | Appalachian FC | 4 | | | |
| 4 | Apotheos FC | 1 | | | |
| 4 | Apotheos FC | 1 | 1 | Appalachian FC | 6 |
| | | | 3 | North Alabama SC | 2 |
| 2 | Georgia Revolution FC | 0 | 3 | North Alabama SC | 2 |
| 3 | North Alabama SC | 1 | | | |
Bold = winner * = after extra time, ( ) = penalty shootout score

### Regional and National playoffs

| Regional Quarterfinals July 19 | Regional Quarterfinals July 19 | Regional Quarterfinals July 19 | Regional semifinals July 16–22 | Regional semifinals July 16–22 | Regional semifinals July 16–22 | Regional Finals July 23–24 | Regional Finals July 23–24 | Regional Finals July 23–24 | National semifinals July 30 | National semifinals July 30 | National semifinals July 30 | National Final August 6 | National Final August 6 | National Final August 6 |
| | | | MW1 | Muskegon Risers | 5 | | | | | | | | | |
| | | | MW4 | Duluth FC | 2 | | | | | | | | | |
| MW4 | Duluth FC | 3 | MW4 | Duluth FC | 2 | | | | | | | | | |
| MW5 | FC Columbus | 1 | | | | | | | | | | | | |
| MW5 | FC Columbus | 1 | | | | MW1 | Muskegon Risers | 1 | | | | | | |
| | | | | | | MW3 | Cleveland SC | 0 | | | | | | |
| | | | MW2 | Med City FC | 0 | | | | | | | | | |
| | | | MW3 | Cleveland SC | 2 | | | | | | | | | |
| MW3 | Cleveland SC | 2 | MW3 | Cleveland SC | 2 | | | | | | | | | |
| MW6 | Pittsburgh Hotspurs | 1 | | | | | | | | | | | | |
| MW6 | Pittsburgh Hotspurs | 1 | | | | | | | 1 | Muskegon Risers | 0 | | | |
| | | | | | | | | | 4 | Crossfire Redmond | 3 | | | |
| | | | GG1 | Sacramento Gold FC | 0 | | | | | | | | | |
| | | | GG2 | El Farolito | 3 | | | | | | | | | |
| | | | | | | W1 | El Farolito | 2(2) | | | | | | |
| | | | | | | W2 | Crossfire Redmond | 2(4) | | | | | | |
| | | | PN2 | Crossfire Redmond | 4 | | | | | | | | | |
| | | | PS2 | FC Arizona | 0 | | | | | | | | | |
| | | | | | | | | | | | | 4 | Crossfire Redmond | 3 |
| | | | | | | | | | | | | 3 | FC Motown | 4 |
| | | | S1 | JAX Armada U23 | 3 | | | | | | | | | |
| | | | S4 | Naples United FC | 1 | | | | | | | | | |
| | | | | | | S1 | JAX Armada U23 | 0 | | | | | | |
| | | | | | | S2 | Tulsa Athletic | 2 | | | | | | |
| | | | S2 | Tulsa Athletic | 0(6) | | | | | | | | | |
| | | | S3 | Laredo Heat SC | 0(5) | | | | | | | | | |
| | | | | | | | | | 2 | Tulsa Athletic | 1 | | | |
| | | | | | | | | | 3 | FC Motown | 2 | | | |
| | | | E1 | FC Motown | 4 | | | | | | | | | |
| | | | E4 | New York Shockers | 1 | | | | | | | | | |
| | | | | | | E1 | FC Motown | 3 | | | | | | |
| | | | | | | E3 | Appalachian FC | 0 | | | | | | |
| | | | E2 | Alexandria Reds | 1 | | | | | | | | | |
| | | | E3 | Appalachian FC | 2 | | | | | | | | | |
Bold = winner * = after extra time, ( ) = penalty shootout score
* ^ $^B$ The Midwest Region semifinals and final were hosted by Muskegon Risers at Oakridge High School (Egelston Township, MI).
* ^ $^C$ The remaining four teams are reseeded for the national semifinals.

### 2022 NPSL National Championship

Paul Patterson, Justen Lopez
Championship MVP: Coby Handy Jean Rodriguez (MOT)