# U.S. Route 22

U.S. Route 22 (US 22) is a major east–west route and one of the original United States Numbered Highways, founded in 1926. It runs from Cincinnati, Ohio, at US 27, US 42, US 127, and US 52 to Newark, New Jersey, at US 1/9 at the Newark Airport Interchange.
US 22 is named the William Penn Highway through most of Pennsylvania. In southwest Ohio, it overlaps with State Route 3 (SR 3) and is familiarly known as the 3-C Highway, "22 and 3", and Montgomery Road.
A section of US 22 in Pennsylvania between New Alexandria at US 119 and Harrisburg at Interstate 81 (I-81) has been designated a part of Corridor M of the Appalachian Development Highway System.

## Route description

Lengths :
| | mi | km |
| OH | 244.10 | 392.84 |
| WV | 6.01 | 9.67 |
| PA | 338.20 | 544.28 |
| NJ | 60.53 | 97.41 |
| Total | 648.84 | 1,044.21 |

### Ohio

US 22 has its westernmost endpoint in downtown Cincinnati. Its eastbound and westbound endpoints are not at the same intersection. Officially, US 22 eastbound begins on Central Avenue (US 27 northbound/US 52 westbound/US 127 northbound) at 5th Street, then proceeds north, turning east onto 7th Street. Meanwhile, US 22 westbound follows 9th Street and officially ends at Central Avenue (signage designating the end occurs much sooner, approaching Elm Street, US 42 northbound).
From downtown Cincinnati to Washington Court House, US 22 roughly follows the historic 3-C Highway which connected Cincinnati, Columbus, and Cleveland. This section is also concurrent with SR 3. At Washington Court House, SR 3 and US 22 diverge. US 22 continues to the east through Circleville to Lancaster. From Lancaster to Zanesville, US 22 roughly follows the route of Zane's Trace, an early pioneer road blazed by Ebenezer Zane beginning in 1796.
Starting just west of Cadiz, US 22 becomes a limited-access expressway for the remainder of its approximately 30 miles (48 km) in Ohio as it approaches and enters Greater Pittsburgh (with the exception of an at-grade intersection with no stoplights or signs on US 22 and narrowing to two lanes for about a mile (1.6 km) east of Cadiz). It junctions with SR 7 for roughly a mile (1.6 km) along the Ohio River shoreline in Steubenville.

### West Virginia

Known as the Robert C. Byrd Expressway, the expressway route that began roughly 30 miles (48 km) to the west near Cadiz, Ohio, continues for approximately five miles (8.0 km) within the state of West Virginia (the highway runs concurrent with West Virginia Route 2, or WV 2, for one of those miles, or 1.6 km) as it approaches more population density within Greater Pittsburgh. US 22 travels through or borders the city of Weirton for its entire length in West Virginia, from the Ohio state line over the Ohio River, to the Pennsylvania state line.

### Pennsylvania

US 22 enters Pennsylvania as a limited-access highway connecting Weirton, West Virginia, and Steubenville, Ohio, with Pittsburgh. Through much of Greater Pittsburgh, it overlaps I-376 and US 30. US 30 merges with US 22 near Imperial and Pittsburgh International Airport, and both highways then merge with I-376 in Robinson Township. Together, these three highways form a busy, limited-access multiplex through the city of Pittsburgh. US 30 then splits from I-376 and US 22 in Wilkinsburg, and the I-376/US 22 concurrency continues to the Pennsylvania Turnpike in Monroeville, where I-376 ends.
East of I-376, US 22 continues east of Pittsburgh as a primary arterial highway. The entire length between Pittsburgh and US 220 and I-99 just west of Altoona was widened to at least four lanes by mid-2011. I-99 links the highway to State College and the Pennsylvania Turnpike. Heading east from I-99, US 22 narrows and becomes the primary highway linking Hollidaysburg and Huntingdon. Near Mount Union, it forms a concurrency with US 522, and the two highways go northeast along the Juniata River to Lewistown.
In Lewistown, US 22 breaks with US 522 and forms a concurrency with US 322, and the two routes travel southeast, mostly as an expressway, toward Harrisburg. At the north end of Harrisburg, US 22 and US 322 split and US 22 runs southward toward the Pennsylvania Farm Show Complex & Expo Center. From there, it turns eastward along Arsenal Boulevard, Herr Street, and Walnut Street to Jonestown Road. Through Dauphin and Lebanon counties, US 22 parallels I-81 and I-78 to the south as a four-lane arterial. East of Fredericksburg, along the border between Lebanon and Berks counties, US 22 forms a concurrency with I-78, which runs to the Allentown area. Former highway alignments of US 22 that parallel this section are collectively known as the "Hex Highway", so called because of the Berks County-based Pennsylvania Dutch families that hang hex signs on their barns.
In the Lehigh Valley, US 22 is a four-lane limited-access expressway between Easton and I-78 to the west; it is dually designated with the Lehigh Valley Thruway in Allentown. The original designation for this expressway was to be I-78, but local opposition to a freeway in Phillipsburg, along with substandard conditions at Easton, forced federal highway officials to relocate I-78 south of Allentown, Bethlehem, Easton, and Phillipsburg. US 22 then crosses the Delaware River on the Easton–Phillipsburg Toll Bridge.

### New Jersey

US 22 in New Jersey predates and was largely replaced by I-78 after I-78 was built between 1956 and 1989 and shares designation with I-78 from exit 3 to exit 18. US 22 was an expressway in some segments, including the area around Perryville and Clinton. It connects Phillipsburg with Newark in New Jersey.
US 22 has one major interchange besides I-78, that being I-287, although it is not a full interchange, with two missing movements: US 22 eastbound to I-287 northbound and I-287 southbound to US 22 westbound.
One of two level crossing of the highway happens in Union County in the Union Township section of the highway (the other occurring in Lewistown, Pennsylvania). It once belonged to the Rahway Valley Railroad; the crossing was closed in 1992 when service on the railroad was ended.

## History

US 22 is one of the original U.S. Highways. In the 1925 plan, it was initially designed to terminate in Cleveland, Ohio, entering Ohio on modern US 422. In the finalized 1926 plan, however, it followed the current course to US 40, where it ended. In 1932, it was extended to Cincinnati as it is currently, replacing SR 10 and following preexisting SR 3.
Before the Byrd Expressway, West Virginia's segment of US 22 ran from Pennsylvania Avenue at the West Virginia–Pennsylvania state line to Main Street, then left on Main Street through downtown Weirton (aligning US 22 with WV 2), and right on Freedom Way to the Fort Steuben Bridge and Ohio River to Steubenville, Ohio. US 22 Alternate (US 22 Alt.) ran along Cove Road from Pennsylvania Avenue to the intersection of Harmon Creek Road (left turn) and the continuation of Cove Road.
With the opening of the first segment of the Byrd Expressway on March 9, 1972, US 22 was reassigned, starting on the new road from the West Virginia–Pennsylvania state line, continuing on Cove Road where the expressway ended and joining the remainder of the original route at Main Street. The Pennsylvania Avenue segment of US 22 from Colliers Way to Main Street was reassigned as WV 105 and US 22 Alt. was reassigned as WV 507. In 2003, WV 507 was extended along the previous US 22 alignment from Cove Road to the Fort Steuben Bridge and was reassigned as CR 507. The Fort Steuben Bridge, which originally carried US 22 across the Ohio River until the construction of the Veterans Memorial Bridge, was permanently closed on January 8, 2009, and demolished by detonation on February 21, 2012.

## Major intersections

| State | County | Location | mi | km | Exit | Destinations | Notes |
| Ohio | Hamilton | Cincinnati | 0.00 | 0.00 | | US 27 south / US 42 south / US 52 east / US 127 south (Central Avenue) / 5th Street West | Western terminus of US 27 / US 42 south / US 52 / US 127 concurrency; southern terminus of SR 3 |
| Ohio | Hamilton | Cincinnati | 0.09 | 0.14 | | US 50 west / SR 264 west (Sixth Street West) / I-75 north | Eastern terminus of SR 264; western terminus of one-way pair; exit 1E on I-75 south |
| Ohio | Hamilton | Cincinnati | 0.17 | 0.27 | | US 27 north / US 52 west / US 127 north (Central Avenue) / 7th Street West | Eastern terminus of US 27 / US 42 south / US 52 / US 127 concurrency |
| Ohio | Hamilton | Cincinnati | 0.33 | 0.53 | | Elm Street (US 42 north) | |
| Ohio | Hamilton | Cincinnati | 0.87 | 1.40 | | Broadway Street | Eastern terminus of one-way pair |
| Ohio | Hamilton | Cincinnati | 1.26 | 2.03 | | I-71 north – Columbus | Northbound exit only; exit 2B on I-71 south |
| Ohio | Hamilton | Cincinnati | 1.58 | 2.54 | | Elsinore Place to I-471 / I-71 north | To US 42 |
| Ohio | Hamilton | Cincinnati | 1.89 | 3.04 | | Eden Park Drive to I-471 / I-71 south | |
| Ohio | Hamilton | Cincinnati | 4.49 | 7.23 | | I-71 south – Louisville | Exit 5 on I-71 north |
| Ohio | Hamilton | Norwood | 5.93 | 9.54 | | SR 561 south (Sherman Avenue) | Western terminus of SR 561 concurrency |
| Ohio | Hamilton | Norwood | 6.25 | 10.06 | | SR 562 to I-75 / I-71 | Exit 3 on SR 562 (Norwood Lateral Expressway); access via Norwood Avenue |
| Ohio | Hamilton | Norwood | 6.46 | 10.40 | | SR 561 north (Ross Avenue) | Eastern terminus of SR 561 concurrency |
| Ohio | Hamilton | Kenwood | 11.41 | 18.36 | | I-71 – Columbus, Cincinnati | Exit 12 on I-71 |
| Ohio | Hamilton | Montgomery | 13.30 | 21.40 | | SR 126 west (Ronald Reagan Highway) | Roundabout; western terminus of SR 126 concurrency |
| Ohio | Hamilton | Montgomery | 13.70 | 22.05 | | SR 126 east (Remington Road) | Eastern terminus of SR 126 concurrency |
| Ohio | Hamilton | Montgomery | 16.15 | 25.99 | | I-275 to I-71 / SR 32 – Kentucky | Exit 50 on I-275 |
| Ohio | Warren | Hopkinsville | 24.64 | 39.65 | | SR 48 – South Lebanon, Maineville | |
| Ohio | Warren | Morrow | 29.97 | 48.23 | | SR 123 north – Lebanon | Western terminus of SR 123 concurrency |
| Ohio | Warren | Salem Township | 31.70 | 51.02 | | SR 123 south – Blanchester | Eastern terminus of SR 123 concurrency |
| Ohio | Warren | Washington Township | 37.54 | 60.41 | | SR 350 – Fort Ancient | |
| Ohio | Clinton | Adams Township | 41.66 | 67.05 | | SR 380 north – Xenia | Southern terminus of SR 380 |
| Ohio | Clinton | Wilmington | 48.00 | 77.25 | | US 68 / SR 134 (South Street) | |
| Ohio | Clinton | Union Township | 51.10 | 82.24 | | SR 73 to I-71 south – Hillsboro, Waynesville | Interchange |
| Ohio | Clinton | Reesville | 56.75 | 91.33 | | SR 72 – Highland, Jamestown | |
| Ohio | Clinton | Sabina | 58.89 | 94.77 | | SR 729 (Howard Street) | |
| Ohio | Fayette | Washington Court House | 68.52 | 110.27 | | US 35 to I-71 – Dayton, Chillicothe, Fairgrounds | Exit 82 on US 35; access via collector-distributor roads |
| Ohio | Fayette | Washington Court House | 69.69 | 112.16 | | US 62 west (Leesburg Avenue) / SR 41 south (Highland Avenue) | Western terminus of US 62 / SR 41 concurrency |
| Ohio | Fayette | Washington Court House | 70.08 | 112.78 | | SR 41 north (North Street) | Eastern terminus of SR 41 concurrency |
| Ohio | Fayette | Washington Court House | 70.32 | 113.17 | | US 62 west / SR 3 north (Columbus Avenue) | Eastern terminus of US 62 / SR 3 concurrency |
| Ohio | Fayette | Washington Court House | 72.39 | 116.50 | | SR 753 to US 35 Byp. | |
| Ohio | Pickaway | Atlanta | 83.10 | 133.74 | | SR 207 – Mount Sterling, Deer Creek, Chillicothe | |
| Ohio | Pickaway | Wayne Township | 92.40 | 148.70 | | SR 138 west – Clarksburg | Eastern terminus of SR 138 |
| Ohio | Pickaway | Wayne Township | 94.20 | 151.60 | | SR 104 – Columbus, Chillicothe | |
| Ohio | Pickaway | Wayne Township | 95.62 | 153.89 | | SR 56 west – Mount London, London | Western terminus of SR 56 concurrency |
| Ohio | Pickaway | Circleville | 96.79 | 155.77 | | US 23 – Columbus, Chillicothe | Interchange |
| Ohio | Pickaway | Circleville | 97.18 | 156.40 | | SR 188 east (Court Street) | Western terminus of SR 188 |
| Ohio | Pickaway | Circleville | 97.83 | 157.44 | | SR 56 east (Main Street) | Eastern terminus of SR 56 concurrency |
| Ohio | Pickaway–Fairfield county line | Washington–Clearcreek township line | 103.53 | 166.62 | | SR 674 north | Southern terminus of SR 674 |
| Ohio | Fairfield | Hocking Township | 113.09 | 182.00 | | SR 159 south – Tarlton | Northern terminus of SR 159 |
| Ohio | Fairfield | Hocking Township | 114.16 | 183.72 | | US 33 – Logan, Columbus | Interchange |
| Ohio | Fairfield | Lancaster | 117.14 | 188.52 | | SR 188 west (Cedar Hill Road) | Western terminus of SR 188 concurrency |
| Ohio | Fairfield | Lancaster | 117.64 | 189.32 | | SR 158 north (Columbus Street) | Southern terminus of SR 158 |
| Ohio | Fairfield | Lancaster | 117.93 | 189.79 | | SR 37 west (High Street) | Western terminus of SR 37 concurrency |
| Ohio | Fairfield | Lancaster | 118.77 | 191.14 | | SR 188 east (Cherry Street) | Eastern terminus of SR 188 concurrency |
| Ohio | Fairfield | Lancaster | 121.58 | 195.66 | | SR 37 east – Bremen, Junction City, New Lexington | Eastern terminus of SR 37 concurrency |
| Ohio | Fairfield | Rushville | 127.92 | 205.87 | | SR 664 to SR 256 – Bremen | |
| Ohio | Perry | Somerset | 135.61 | 218.24 | | SR 668 south | Western terminus of SR 668 concurrency |
| Ohio | Perry | Somerset | 135.78 | 218.52 | | SR 13 (Columbus Street) | Traffic circle |
| Ohio | Perry | Somerset | 136.37 | 219.47 | | SR 668 north – Brownsville, Flint Ridge | Eastern terminus of SR 668 concurrency |
| Ohio | Perry | Madison Township | 141.70 | 228.04 | | SR 204 west – Millersport | Eastern terminus of SR 240 |
| Ohio | Muskingum | East Fultonham | 146.35 | 235.53 | | SR 345 south – East Fultonham, New Lexington, Perry State Forest | Northern terminus of SR 345 |
| Ohio | Muskingum | Newton Township | 150.30 | 241.88 | | SR 93 south – Roseville, Crooksville | Western terminus of SR 93 concurrency |
| Ohio | Muskingum | South Zanesville | 153.62 | 247.23 | | SR 719 east to SR 60 / SR 146 / SR 555 | Western terminus of SR 719 |
| Ohio | Muskingum | Zanesville | 155.87 | 250.85 | | US 40 west (Main Street) | Western terminus of US 40 concurrency |
| Ohio | Muskingum | Zanesville | 155.93 | 250.95 | | SR 60 south / SR 146 east (9th Street) to I-70 | Western terminus of SR 60 / SR 146 concurrency |
| Ohio | Muskingum | Zanesville | 156.05 | 251.14 | | SR 60 north / SR 146 west (Underwood Street) | Eastern terminus of SR 60 / SR 146 concurrency |
| Ohio | Muskingum | Pleasant Grove | 158.43 | 254.97 | | SR 93 north | Eastern terminus of SR 93 concurrency |
| Ohio | Muskingum | Perry Township | 165.54 | 266.41 | | I-70 – Wheeling, Columbus | Exit 164 on I-70 |
| Ohio | Muskingum | New Concord | 170.74 | 274.78 | | SR 83 to I-70 | |
| Ohio | Guernsey | Cambridge | 177.18 | 285.14 | | SR 723 south to I-70 | Northern terminus of SR 723 |
| Ohio | Guernsey | Cambridge | 179.23 | 288.44 | | SR 209 west (5th Street) | Western terminus of SR 209 concurrency |
| Ohio | Guernsey | Cambridge | 179.51 | 288.89 | | SR 209 east (Southgate Parkway) to I-70 | Eastern terminus of SR 209 concurrency |
| Ohio | Guernsey | Cambridge | 179.84 | 289.42 | | US 40 east (Wheeling Avenue) | Eastern terminus of US 40 concurrency |
| Ohio | Guernsey | Cambridge Township | 181.98 | 292.87 | | I-77 – Marietta, Cleveland | Exit 47 on I-77 |
| Ohio | Guernsey | Jefferson Township | 188.31 | 303.06 | | Salt Fork State Park | |
| Ohio | Guernsey | Madison Township | 191.11 | 307.56 | | SR 285 (Jefferson Road) | |
| Ohio | Guernsey | Antrim | 194.96 | 313.76 | | SR 513 south to I-70 | Northern terminus of SR 513 |
| Ohio | Guernsey | Londonderry Township | 202.55 | 325.97 | | SR 800 south – Barnesville | Western terminus of SR 800 concurrency |
| Ohio | Harrison | Freeport Township | 203.16 | 326.95 | | SR 800 north – Freeport, Clendening Dam | Eastern terminus of SR 800 concurrency |
| Ohio | Harrison | Piedmont | 206.02 | 331.56 | | SR 331 east – Holloway | Western terminus of SR 331 |
| Ohio | Harrison | Cadiz Township | 212.54 | 342.05 | | SR 519 east – New Athens | Western terminus of SR 519 |
| Ohio | Harrison | Cadiz | 219.29 | 352.91 | 219 | US 250 west – New Philadelphia | Western terminus of US 250 concurrency |
| Ohio | Harrison | Cadiz | 220.14 | 354.28 | 220 | US 250 east / SR 9 – Scio, Cadiz, Bridgeport | Eastern terminus of US 250 concurrency |
| Ohio | Harrison | Green Township | 224.53 | 361.35 | 224 | SR 151 west – Jewett, Scio | Western terminus of SR 151 concurrency |
| Ohio | Harrison | Hopedale | 226.27 | 364.15 | 226 | SR 151 east – Hopedale, Smithfield | Eastern terminus of SR 151 concurrency |
| Ohio | Harrison | Green Township | 227.87 | 366.72 | - | Township Road 65 | Western terminus of freeway section |
| Ohio | Jefferson | Bloomingdale | 231.37 | 372.35 | 231 | SR 152 – Bloomingdale, Fairgrounds | |
| Ohio | Jefferson | Wayne Township | 233.78 | 376.23 | 233 | Reeds Mills, Broadacre | Access via CR 22A |
| Ohio | Jefferson | Reeds Mill | 235.21– 235.25 | 378.53– 378.60 | 235 | CR 22A – Wintersville, Reeds Mills | Eastbound exit and westbound entrance |
| Ohio | Jefferson | Wintersville | 237.48 | 382.19 | 237 | SR 43 – Carrollton, Wintersville | |
| Ohio | Jefferson | ​ | 240.18 | 386.53 | 240 | Lovers Lane – Steubenville | |
| Ohio | Jefferson | ​ | 241.81 | 389.16 | 241 | John Scott Highway – Steubenville | Serves Eastern Gateway Community College |
| Ohio | Jefferson | Alikanna | 242.90 | 390.91 | 242 | SR 7 north / SR 213 north – East Liverpool | Western terminus of SR 7 concurrency; southern terminus of SR 213 (not signed westbound) |
| Ohio | Jefferson | Steubenville | 243.81 | 392.37 | 244A | SR 7 south – Downtown | Eastern terminus of SR 7 concurrency; signed as exit 244 westbound |
| Ohio | Jefferson | Steubenville | 244.20 | 393.00 | 244B | University Boulevard | Westbuond exit is via exit 244A; serves Franciscan University of Steubenville |
| Ohio River | Ohio River | Ohio River | 244.320.0 | 393.190.0 | Veterans Memorial Bridge | Veterans Memorial Bridge | Veterans Memorial Bridge |
| West Virginia | Brooke | ​ | 0.6 | 0.97 | 1 | WV 2 south – Follansbee, Wheeling | Western terminus of WV 2 concurrency |
| West Virginia | Brooke | ​ | 1.2 | 1.9 | 2 | WV 2 north (Main Street) – Downtown Weirton | Eastern terminus of WV 2 concurrency |
| West Virginia | Hancock | No major junctions | No major junctions | No major junctions | No major junctions | No major junctions | No major junctions | No major junctions | No major junctions |
| West Virginia | Brooke | Weirton | 3.2 | 5.1 | 3 | CR 507 (Harmon Creek Road) / CR 1 (Cove Road) | |
| West Virginia | Brooke | Weirton | 4.3 | 6.9 | 4 | CR 13 (Three Springs Drive) – Weirton | No CR 13 signage eastbound; serves West Virginia Northern Community College |
| West Virginia | Brooke–Hancock county line | Weirton | 5.5 | 8.9 | 5 | WV 105 (Colliers Way) | |
| West Virginia | Hancock | Weirton | 6.0 | 9.7 | — | US 22 east – Pittsburgh | Continuation into Pennsylvania |
| 1.000 mi = 1.609 km; 1.000 km = 0.621 mi Concurrency terminus Incomplete access ||||||||