OpenLLM-France/wikimedia huggingface dataset:
# Dacarbazine

Dacarbazine, also known as imidazole carboxamide and sold under the brand name DTIC-Dome, is a chemotherapy medication used in the treatment of melanoma and Hodgkin's lymphoma. For Hodgkin's lymphoma it is often used together with vinblastine, bleomycin, and doxorubicin. It is given by injection into a vein.
Common side effects include loss of appetite, vomiting, low white blood cell count, and low platelets. Other serious side effects include liver problems and allergic reactions. It is unclear if use in pregnancy is safe for the baby. Dacarbazine is in the alkylating agent and purine analog families of medication.
Dacarbazine was approved for medical use in the United States in 1975. It is on the World Health Organization's List of Essential Medicines.

## Medical uses

As of mid-2006, dacarbazine is commonly used as a single agent in the treatment of metastatic melanoma, and as part of the ABVD chemotherapy regimen to treat Hodgkin's lymphoma, and in the MAID regimen for sarcoma. Dacarbazine was proven to be just as efficacious as procarbazine, another drug with similar chemistry, in the German trial for paediatric Hodgkin's lymphoma, without the teratogenic effects. Thus COPDAC has replaced the former COPP regime in children for TG2 & 3 following OEPA.

## Side effects

Like many chemotherapy drugs, dacarbazine may have numerous serious side effects, because it interferes with normal cell growth as well as cancer cell growth. Among the most serious possible side effects are birth defects to children conceived or carried during treatment; sterility, possibly permanent; or immune suppression (reduced ability to fight infection or disease). Dacarbazine is considered to be highly emetogenic, and most patients will be pre-medicated with dexamethasone and antiemetic drugs like 5-HT$_3$ antagonist (e.g., ondansetron) and/or NK$_1$ receptor antagonist (e.g., aprepitant). Other significant side effects include headache, fatigue and occasionally diarrhea.
The Swedish National Board of Health and Welfare has sent out a black box warning and suggests avoiding dacarbazine due to liver problems.

## Mechanism of action

Dacarbazine is activated by liver microsomal enzymes to monomethyl triazeno imidazole carboxamide (MTIC), which is an alkylating compound. It causes methylation, modification and cross linking of DNA, thus inhibiting DNA, RNA and protein synthesis.

## Synthesis

Nitrous acid is added to 5-aminoimidazol-4-carboxamide to make 5-diazoimidazol-4-carboxamide. It reacts with dimethylamine to give dacarbazine.

## History

In 1959, dacarbazine was first synthesized at Southern Research in Alabama. The research was funded by a US federal grant. Dacarbazine gained FDA approval in May 1975 as DTIC-Dome. The drug was initially marketed by Bayer.

## Society and culture

There are generic versions of dacarbazine available from APP, Bedford, Mayne Pharma (Hospira) and Teva.
# Weightlifting at the 2015 Pan American Games – Men's 77 kg

The men's 77 kg competition of the weightlifting events at the 2015 Pan American Games in Toronto, Canada, was held on July 12 at the Oshawa Sports Centre. The defending champion was Ivan Cambar from Cuba.
Each lifter performed in both the snatch and clean and jerk lifts, with the final score being the sum of the lifter's best result in each. The athlete received three attempts in each of the two lifts; the score for the lift was the heaviest weight successfully lifted.

## Schedule

All times are Eastern Daylight Time (UTC-4).
| Date | Time | Round |
| July 13, 2015 | 14:00 | Final |

## Results

11 athletes from ten countries took part.
| Rank | Name | Country | Group | B.weight (kg) | Snatch (kg) | Clean & Jerk (kg) | Total (kg) |
| | Addriel Garcia Lao | Cuba | A | 75.61 | 153 | 185 | 338 |
| | Junior Sánchez | Venezuela | A | 75.13 | 155 | 182 | 337 |
| | Jhor Moreno | Colombia | A | 76.75 | 146 | 182 | 328 |
| 4 | Travis Cooper | United States | A | 76.85 | 146 | 179 | 325 |
| 5 | Juan Peña | Dominican Republic | A | 76.47 | 144 | 180 | 324 |
| 6 | Domingo Roman | Mexico | A | 75.85 | 145 | 176 | 321 |
| 7 | Ricardo Flores | Ecuador | A | 76.43 | 137 | 180 | 317 |
| 8 | Bástian López | Chile | A | 76.32 | 136 | 176 | 312 |
| 9 | Jérôme Boisclair | Canada | A | 76.57 | 130 | 160 | 290 |
| | Darryl Conrad | Canada | A | 76.39 | 128 | - | |
| | Brien Best | Barbados | A | 75.66 | - | - | DNF |
# Nikka Whisky Distilling

The Nikka Whisky Distilling Co. Ltd. (ニッカウヰスキー株式会社, Nikka Uwisukī Kabushiki-gaisha) is a producer of Japanese whisky and other beverages headquartered in Tokyo. It is owned by Asahi Group Holdings.
The company operates a number of distilleries and other facilities in Japan, including two Japanese whisky distilleries, the Yoichi distillery in Yoichi, Hokkaidō (established in 1934), and the Miyagikyo distillery in Aoba-ku, Sendai, Miyagi Prefecture, Northern Honshū (established in 1969). It also owns the Ben Nevis Distillery (acquired in 1989) in Scotland.

## History

The founder, Masataka Taketsuru, travelled to Scotland in 1918 to learn the process of distilling Scotch whisky first hand. He studied organic chemistry under Prof. T. S. Patterson at the University of Glasgow and malt whisky production at the Hazelburn distillery, in Campbeltown near the Mull of Kintyre. He married Jessie Roberta "Rita" Cowan, the daughter of a Glasgow doctor, and returned with her to Japan in 1920. In 1923 he joined Kotobukiya (currently Suntory) and helped to establish a distillery before starting Nikka in 1934.
After their deaths, the company was run by their adoptive son, Takeshi Taketsuru, who expanded its business substantially.

## Products

Nikka produces a wide variety of Japanese whiskies, ranging from ¥900 (per 700 ml bottle) Black Nikka sold in Japanese convenience stores, to the ¥15,750 (per 750 ml bottle) Nikka Single Cask. In 2008, Yoichi 20 Year Old was voted best single malt at the World Whiskies Awards.
Black Nikka is a 37% alcoholic whisky, available at corner stores throughout Japan in 180, 300, 700, 1800, 1920, 2700, and 4000 mL bottles. Individual servings, pre-mixed with soda or water, are also available.
Nikka has been owned by Asahi Group Holdings since 1954.

### Whiskies

* Yoichi Single Malt
* Miyagikyo Single Malt
* From The Barrel
* Taketsuru Pure Malt
* Taketsuru Pure Malt 17-Year
* Coffey Malt
* Coffey Grain
* Pure Malt Red
* Pure Malt Black
* Pure Malt White
* All Malt
* Blended
* Ben Nevis

## Distilleries and plants

* Yoichi distillery, Hokkaido Plant (Yoichi, Hokkaido) – malt whisky distilling, bottling
* Miyagikyo distillery, Sendai Plant (Sendai, Miyagi) – malt whisky distilling, grain whisky production, bottling
* Hirosaki Plant (Hirosaki, Aomori) – cider, brandy and wine brewing, distilling, bottling
* Tochigi Plant (Sakura, Tochigi) – grain whisky storage & ageing, re-storage of blended whisky
* Kashiwa Plant (Kashiwa, Chiba) – bottling
* Nishinomiya Plant (Nishinomiya, Hyogo) – liqueur bottling
* Moji Plant (Kitakyushu, Fukuoka) – shōchū distilling, bottling
* Ben Nevis distillery (Fort William, Scotland, UK) – Scotch whisky production
# RW Kember

Reginald Walter Kember (born 15 April 1983) is a South African rugby union footballer. He plays either as a flanker or eighthman. He most recently represented the Pumas in the Currie Cup and Vodacom Cup having previously played for the Mighty Elephants, Golden Lions and Leopards.
# Hiroka Yaginuma

Hiroka Yaginuma (born September 23, 1981) is a Japanese born professional wrestler. She is best known for her work in the Mexican professional wrestling promotion Consejo Mundial de Lucha Libre (CMLL). Yaginuma has worked under the ring names Hiroka Yaginuma and "Raven Hiroka" but is now billed simply as Hiroka. She is a former holder of the CMLL World Women's Championship. Yaginuma is married to Mexican Mini-Estrella Pequeño Damián 666 who also works for CMLL.

## Professional wrestling career

Hiroka Yaginuma trained under Mima Shimoda and Shinobu Kandori before her professional wrestling debut, and would later receive further training from Jose Luis Feliciano and El Hijo Del Gladiador when she began working for Consejo Mundial de Lucha Libre (CMLL) in Mexico. Yaginuma made her debut on September 18, 2002, and initially worked in her native Japan. In 2005, she began working regularly for the Mexican wrestling promotion CMLL as she moved from Japan to Mexico to live. Initially she wrestled under her full name but later changed to "Raven Hiroka" and later on to simply "Hiroka". On June 9, 2006, Hiroka defeated Marcela to win the CMLL World Women's Championship in Mexico City, D. F. Over the next six months Hiroka would successfully defend the championship against Marcela on several occasions, India Sioux, Dark Angel and Lady Apache. On October 13, 2006, Hiroka defeated Lady Apache in a Luchas de Apuestas (Spanish for "Bet match"), forcing Lady Apache to have her hair shaved off after the match. Two months later, on December 25, 2006, Lady Apache gained a measure of revenge by winning the CMLL Women's title from Hiroka.
In September, 2009 Hiroka formed a group rudo (villain) called Las Zorras ("The Foxes") along with Princesa Sujei and Princesa Blanca.

## Personal life

Yaginuma is married to Mexican Mini-Estrella Pequeño Damián 666 who also works for CMLL. The couple opened up an exclusive pet shop in Mexico City in March, 2010. In June, 2010 Hiroka announced that she would be retiring from wrestling to focus on having a child.

## Championships and accomplishments

* Consejo Mundial de Lucha Libre
** CMLL World Women's Championship (1 time)

## Luchas de Apuestas record

| Winner (wager) | Loser (wager) | Location | Event | Date | Notes |
| Hiroka (hair) | Lady Apache (hair) | Mexico City | CMLL show | October 13, 2006 | |
# WTA Sydney Open

The WTA Sydney Open, was a professional women's tennis tournament held in Sydney, Australia. The event, the first tournament in Australia exclusively for women, was played under various sponsored names as part of the WTA Tour and took place in November or the first half of December from 1976 through 1979. It was played on outdoor grass courts at the White City Stadium.

## Finals
### Singles

| Year | Sponsored Name | Winners | Runners-up | Score |
| 1976 | Colgate International Women's Championships | Martina Navratilova | Betty Stöve | 7–5, 6–2 |
| 1977 | Colgate International of Australia | Evonne Goolagong Cawley | Kerry Reid | 6–1, 6–3 |
| 1978 | Toyota Women's Classic | Dianne Fromholtz | Kerry Reid | 6–1, 1–6, 6–4 |
| 1979 | NSW Building Society Women's Classic | Sue Barker | Rosalyn Fairbank | 6–0, 7–5 |

### Doubles

| Year | Champions | Runners-up | Score |
| 1976 | Martina Navratilova Betty Stöve | Françoise Dürr Ann Kiyomura | 6–3, 7–5 |
| 1977 | Evonne Goolagong Cawley / Betty Stöve vs. Greer Stevens / Kerry Reid | Evonne Goolagong Cawley / Betty Stöve vs. Greer Stevens / Kerry Reid | divided |
| 1978 | Kerry Reid Wendy Turnbull | Judy Chaloner Anne Hobbs | 6–2, 4–6, 6–2 |
| 1979 | Billie Jean King Wendy Turnbull | Sue Barker Pam Shriver | 7–5, 6–4 |
# WMJS-LP

WMJS-LP is a Full Service formatted low-power broadcast radio station licensed to and serving Prince Frederick, Maryland. WMJS-LP is owned and operated by St. Paul's Episcopal Church.

## Programming/Call Sign

While WMJS-LP is licensed to an Episcopal parish, the programming on the station is principally secular, with Adult Contemporary, Classic Hits and Country music and community-oriented programming broadcast.
The station was assigned the WMJS-LP call letters by the Federal Communications Commission on December 29, 2003.
# WMKR

WMKR (94.3 FM; "Genuine Country 94.3") is a radio station broadcasting a country music format, licensed to Pana, Illinois, United States. The station serves the Taylorville, Illinois area. WMKR is owned by Miller Communications, Inc.
WMKR'S original city of license was Taylorville, but was changed to Pana when WXKO-FM (100.9 FM, now WZUS) in Pana was sold to a new owner and the frequency was moved to Macon, Illinois.

## HD Radio

On December 26, 2018, WMKR's HD3 subchannel changed its format from soft adult contemporary to oldies, branded as "Cruisin' 96.5" (simulcast on translator W243DN Taylorville).
On January 1, 2021, WMKR-HD3 changed its format from oldies to sports, branded as "96.5 The Winner".
On July 25, 2022, It was announced that WMKR-HD3 will change their format from sports to soft oldies/soft adult contemporary on August 1, branded as "96.5 The Chill".
# Milena Titoneli

Milena Titoneli Guimarães (born 6 August 1998) is a Brazilian taekwondo fighter. She won the gold medal in the women's 67 kg event at the 2019 Pan American Games in Lima, Peru and the 2021 Pan American Taekwondo Championships in Cancún, Mexico. She is also a two-time bronze medalist in this event at the World Taekwondo Championships (2019 and 2022).

## Career

Titoneli started fighting competitively in 2012, and two years later was in the 2014 Summer Youth Olympics. She won a bronze medal in welterweight at the 2019 World Taekwondo Championships, after being defeated by Nur Tatar in the semifinal. She won a gold medal at the 2021 Pan American Taekwondo Championships.
Through the Pan American qualifier, Titoneli earned a spot to represent Brazil at the 2020 Summer Olympics. Titoneli won her first match against Julyana Al-Sadeq, and then lost the quarterfinals to eventual gold medalist Matea Jelić. Jelić's semifinal win sent Titoneli to the repechage, where after beating Lauren Lee, she reached the bronze dispute against Ivorian fighter Ruth Gbagbi, bronze medalist at the Rio 2016 Games. In spite of a balanced fight for most of the match, Titoneli lost and finished in 4th place.
She won one of the bronze medals in the women's welterweight event at the 2022 World Taekwondo Championships held in Guadalajara, Mexico. She competed in the women's welterweight event at the 2023 World Taekwondo Championships held in Baku, Azerbaijan.
# WMLL

WMLL (96.5 FM; "96.5 Live Free Country") is an American radio station licensed to Bedford, New Hampshire, and serving the New Hampshire portion of the Merrimack Valley with a country music format. The station's studios are located on Commercial Street in Manchester. WMLL is owned by Saga Communications, and operates as part of its Manchester Radio Group.

## History

The 96.5 FM frequency first signed on in May 1996 with test broadcasts under the call sign WAEF. Regular broadcasting began on June 27, with a rock format branded "96.5 The Fox"; the call sign was soon changed to WOXF. The station was originally owned by Donna MacNeil.
On July 1, 1997, Saga Communications announced that it had signed a time brokerage agreement to take over WOXF's operations; on July 29, Saga relaunched the station as "Cool 96.5", an oldies station. The call sign was changed to WQLL on August 15, 1997; that month, Saga bought the station outright in a $3.3 million deal that was concluded on November 21, 1997. The station switched to classic rock, branded as "96.5 The Mill", in March 2005; on March 17, the call sign became WMLL. In August 2011, WMLL shifted to a classic hits format. In October 2016, WMLL returned to classic rock, branded as "Iconic Rock".
On December 15, 2023, WMLL flipped to a country music format as "96.5 Live Free Country". The new format was advertised as "Continuous Country Without The Static", as country music was previously available in the Manchester area via adjacent market stations (Portsmouth-market WOKQ, Concord-market WNHW, and two Boston stations); Saga already programmed classic country on the third HD Radio subchannel of WZID and on translators in Concord and Manchester.
# WMLN-FM

WMLN-FM (91.5 FM) is a radio station located at Curry College in Milton, Massachusetts, United States. WMLN is supervised by a faculty member, but is student-run. It broadcasts a college radio block format featuring a variety in music, live talk shows and live coverage of Curry College sports. The station is licensed to serve Milton, and covers the Curry College campus and the Milton-Boston area. WMLN broadcasts continuously throughout the year.
WMLN features programming from Westwood One and AP Radio. From 1968 until 1974, WVAC, the "Voice at Curry", was a carrier-current AM station at Curry College, which later became WMLN-FM on April 1, 1975.
# WMLQ

WMLQ (97.7 FM, "News 97 & 98") is a radio station located in Manistee, Michigan broadcasting a news/talk format, simulcasting WLDN 98.7 FM Ludington.
The station began broadcasting in 1970 under the WMTE-FM call sign (the current WMTE-FM, at 101.5, is unrelated, but was a sister station of WMLQ for a short time in 2012 and 2013). In the 1980s, the station was WRRK, playing Top 40 music. From 1995 to 2006, the station simulcast WVXU in Cincinnati, Ohio as WVXM, an affiliate of the "X-Star Radio Network," which featured a variety of programs, including news, talk, jazz, and adult standards.
After WVXU was sold to the owners of classical station WGUC in Cincinnati, all of WVXA's former repeater stations were sold off to other owners; 97.7 FM was purchased by Synergy Media, owners of classic rock station WWKR in Hart, Michigan. Synergy Media has installed a commercial Soft AC/Oldies/Easy Listening format on 97.7 FM as "The Coast."
The WMLQ calls were formerly used in the 1980s and 1990s at an FM station in Rogers City, Michigan, which coincidentally also operated on the 97.7 FM frequency (it later moved to 96.7) and also played an AC format, under the name "Mello-Q." Also coincidentally, the original WMLQ in Rogers City later became WVXA, also an X-Star Radio Network affiliate; it is now WRGZ and simulcasts WATZ-FM, a commercial country music station in Alpena, Michigan.
On February 1, 2016, WMLQ switched to a simulcast of news/talk-formatted WLDN 98.7 FM Ludington. The "Coast FM" format is now heard on 101.5 WMTE-FM.
The station airs The Steve Gruber Show, the flagship program for The Michigan Talk Network, on delay, in late mornings.
# WMLZ-LP

WMLZ-LP (107.9) is a low-power High School radio station. The station is licensed to Bedford Public Schools in Temperance, Michigan.

## History

WMLZ-LP first began broadcasting in 2002 under the name of Blend 107.9, where it played a mix of 1980s music and current hits. The format was then changed in 2006 to incorporate a wide time range classic rock, and the station changed its name to Z108. In February 2018, the station shifted towards a variety hits format, branded as 107.9 Memories. WMLZ-LP also aired Bedford High School's football and basketball games. In 2022, the station fell silent.
# WMOK

WMOK Metropolis AM is a radio station broadcasting a country music format - airing on 920AM and 93.7FM. Licensed to Metropolis, Illinois, the station serves Southern Illinois, and the Paducah, Kentucky area. WMOK is owned by Withers Broadcasting, which purchased the station in 1997.

## History

The station began broadcasting on February 4, 1951, and originally ran 500 watts during daytime hours only. The station's power was increased to 1,000 watts in 1954. By 1989, the station had added nighttime operations, running 73 watts. In 2008, the station's nighttime power was increased to 750 watts. The station has long aired a country music format.
# WMOZ

WMOZ (106.9 FM, "106.9 The Moose") is a radio station licensed to serve Moose Lake, Minnesota. The station is owned by Fond du Lac Band of Lake Superior Chippewa. It airs a classic hits music format.
The station was assigned the WMOZ call letters by the Federal Communications Commission on June 26, 2002.

## Programming

In addition to its usual music programming, WMOZ carries local high school sports and certain professional sports broadcasts of regional interest. As of the 2007-2008 baseball season, WMOZ is an affiliate of the Minnesota Twins radio network.

## History

In January 2003, the station dropped its simulcast of WKLK-FM and flipped to a country music format. On November 26, 2003, the station flipped to an Oldies format from Jones Radio Network branded as "Oldies 106.9". It eventually shifted to classic hits as "Classic Hits 106.9".
# WMPF-LP

WMPF-LP (91.1 FM) is a radio station licensed to serve the community of Rumford, Maine. The station is owned by the River Valley Community Association and airs a variety format.
The station was assigned the WMPF-LP call letters by the Federal Communications Commission on January 22, 2014.
# WMPX (AM)

WMPX (1490 kHz) is an AM radio station licensed to Midland, Michigan broadcasting a classic hits format, simulcasting WMRX-FM 97.7 Beaverton. The station is imaged as "Sunny 97.7107.7", with 107.7 being the frequency of translator W299CK Midland. Until January 2014, the station featured the America's Best Music format distributed by Westwood One.
Until March 1, 2019, WMPX was simulcast with WMRX-FM 97.7 24/7 except for some local sports play-by-play. Although there are other radio stations licensed to Midland, WMPX is today the only commercial radio station that primarily serves the Midland area (WUGN is a non-commercial religious station and WKQZ is licensed to Midland but has studios in Saginaw).

## History

WMPX began broadcasting in 1948 as WMDN. WMDN was Midland's first radio station, owned by the city's newspaper, the Midland Daily News. That station continued to use that call sign until July 1971.
The station was sold in 1959 to a group of Bay City businessmen.
The station was then sold in 1968 to Patten Broadcasting Co. and changed the call sign in 1971 to WMPX after firm president Myron P. Patten.
WMPX general manager Ronald Maines bought the station from Patten Communications Corp in 1981.
WMPX in Midland, along with WMRX-FM in Beaverton, changed hands again in late 1992 with Steel Broadcasting as the new owners. Steel Broadcasting was headed up by Tom Steel (55 percent) and previous WMPX shareholder Pat Patten (45 percent). Steel, Assistant General Manager at the station at the time of the sale, was originally hired as a sales rep at WMPX in 1977.
On March 1, 2019, WMPX split from its simulcast with WMRX-FM and launched a classic country format, branded as "107.7 The Highway" (simulcast on FM translator W299CK 107.7 FM Midland).
Black Diamond Broadcasting began operating WMPX under a local marketing agreement in October 2020.
In April 2023, Black Diamond Broadcasting exercised an option to purchase WMPX, WMRX-FM, and translator W299CK from Steel Broadcasting. On July 7, 2023, WMPX dropped its classic country format and switched back to a simulcast of WMRX-FM's classic hits format, branded as "Sunny 97.7/107.7". The acquisition by Black Diamond Broadcasting was consummated on October 17, 2023, at a price of $100,000.