# List of disasters in the Czech Republic by death toll

The list of disasters in the Czech Republic by death toll includes major disasters and accidents – excluding warfare and other intentional acts – that took place in the territory of the Czech Republic and resulted in 10 or more fatalities:
| Disaster | Type | Location | Deaths | Date | References |
| Great Famine of 1315–1317 | Famine | Czech Lands | Tens thousands or more | 1315–1317 | |
| Czech Famine | Famine | Czech Lands | 250,000-500,000 | 1770-1772 | |
| Spanish flu | Pandemic | Czechoslovakia | 44,000-82,648 | 1918-1920 | |
| COVID-19 pandemic in the Czech Republic | Pandemic | Czech Republic | 42,806 | 2020-2023 | |
| Marie mine disaster | Mine disaster | Příbram | 319 | 31 May 1892 | |
| Karviná mine disaster | Mine disaster | Karviná | 235 | 14 June 1894 | |
| Bolevec Disaster | Explosion | Třemošná | Over 200 | 25 May 1917 | |
| Nelson III Mine Disaster | Mine disaster | Teplice | 144 | 3 January 1934 | |
| Stéblová train disaster | Trainwreck | Stéblová | 118 | 14 November 1960 | |
| Dukla mine disaster | Mine disaster | Dolní Suchá | 108 | 7 July 1961 | |
| Šakvice train collision | Trainwreck | Šakvice | 103 | 24 December 1953 | |
| Swine flu pandemic | Pandemic | Czech Republic | 102 | 2009 | |
| Inex-Adria Aviopromet Flight 450 | Aircrash | Suchdol, Prague | 79 | 30 October 1975 | Including four people who died in Hospital. |
| Aeroflot Flight 141 | Aircrash | 0.46 km from Prague Ruzyně Airport | 66 | 19 February 1973 | |
| Desná Dam | Dam failure | Jizera Mountains | 65 | 18 September 1916 | |
| 1997 Central European flood | Flood | Oder and Morava river basins | 50 | July 1997 | |
| 2012 Czech Republic methanol poisonings | Poisonings | Czech Republic | 48 | September 2012 | |
| Tachov Explosion | Explosion | Tachov | 47 | 13 December 1973 | |
| Michálka mine disaster | Mine disaster | Slezská Ostrava | 36 | 4 October 1950 | |
| JAT Flight 367 | Aircrash | Srbská Kamenice | 27 | 26 January 1972 | |
| Doubrava mine disaster | Mine disaster | Doubrava | 25 | 7 May 1985 | |
| MESIT Factory Collapse | Building collapse | Uherské Hradiště | 18 | 23 November 1984 | |
| 2002 European floods | Flood | Czech Republic | 17 | August 2002 | |
| 2013 European floods | Flood | Czech Republic | 16 | May–June 2013 | |
| 2023 Prague shooting | Mass murder | Prague | 15 | 21 December 2023 | Including the perpetrator and his father. Perepetrator also killed 2 people in Klánovice Forest on 15 December 2023, six days before the 21 December shootings. |
| 2009 European floods | Flood | Czech Republic | 15 | May–June 2013 | |
| ČSM Mine Explosion | Mine disaster | Karviná District | 13 | 20 December 2018 | |
| Bohumín arson attack | Mass murder | Bohumín | 11 | 8 August 2020 | |

## Significant incidents resulting in fewer than 10 deaths

| Disaster | Type | Location | Deaths | Date |
| Studénka train crash | Trainwreck | Studénka | 8 | 8 August 2008 |
| 2020 Vejprty Fire | Fire | Vejprty disabled people's home | 8 | 19 January 2020 |
| 2021 South Moravia tornado | Tornado | South Moravian Region | 6 | 24 June 2021 |
| 2024 Central European floods | Flood | Czech Republic | 5 | September 2024 |
| Studénka train crash | Trainwreck | Studénka | 3 | 22 July 2015 |
| Milavče train crash | Trainwreck | Milavče | 3 | 4 August 2021 |
| Vrbětice ammunition warehouses explosions | Terrorism | Vrbětice | 2 | 16 October 2014 and 3 December 2014 |
| Bohemian Switzerland Fire | Fire | Bohemian Switzerland | 0 | 23 July 2022 and 12 August 2022 |