# List of Italian football transfers summer 2021

The 2021 Italian football summer transfer window runs from 1 July to 31 August 2021. This list includes transfers featuring at least one club from either Serie A or Serie B that were completed after the end of the winter 2020–21 transfer window on 31 January 2021 and before the end of the 2021 summer window on 31 August. While free agents can join a club at any time, deals between clubs that happened between 1 September and 2 January will be effective starting 3 January, when the winter 2021–22 transfer window will officially open.

## Transfers

Legend
* Those clubs in Italic indicate that the player already left the team on loan on this or the previous season or a new signing that immediately left the club.
| Date | Name | Moving from | Moving to | Fee |
| 17 February 2021 | Luka Stankovski | Rabotnički | Monza | Undisclosed |
| 3 March 2021 | Weston McKennie | Schalke 04 | Juventus | €18,5m |
| 13 April 2021 | Maxime Lopez | OM | Sassuolo | Undisclosed |
| 22 April 2021 | Gabriel Sandberg | Nyköping | Venezia | Undisclosed |
| 29 April 2021 | Alban Lafont | Fiorentina | Nantes | Undisclosed |
| 3 May 2021 | Damiano Pecile | Vancouver Whitecaps | Venezia | Loan |
| 4 May 2021 | Matías Mir | Peñarol | Parma | Free |
| 13 May 2021 | Lucas Boyé | Torino | Elche | Undisclosed |
| 14 May 2021 | Daan Heymans | Waasland-Beveren | Venezia | Free |
| 21 May 2021 | Douglas Costa | Juventus | Grêmio | Loan |
| 26 May 2021 | Gervinho | Parma | Trabzonspor | Free |
| 26 May 2021 | Bruno Peres | Roma | Trabzonspor | Free |
| 27 May 2021 | Mike Maignan | Lille | Milan | Undisclosed |
| 27 May 2021 | Federico Gatti | Pro Patria | Frosinone | Undisclosed |
| 28 May 2021 | Daniele Padelli | Inter | Udinese | Free |
| 28 May 2021 | Luka Koblar | Maribor | Frosinone | Undisclosed |
| 2 June 2021 | Léo Sena | Atlético Mineiro | Spezia | Undisclosed |
| 4 June 2021 | Luigi Cuppone | Casertana | Cittadella | Free |
| 6 June 2021 | Dávid Hancko | Fiorentina | Sparta Prague | Undisclosed |
| 9 June 2021 | Luca Ghiringhelli | Cittadella | Ternana | Free |
| 10 June 2021 | Marco Brescianini | Milan | Monza | Loan |
| 10 June 2021 | Nícolas Andrade | Reggina | Pisa | Free |
| 11 June 2021 | David Schnegg | LASK | Venezia | Undisclosed |
| 11 June 2021 | Davide Mondonico | AlbinoLeffe | Crotone | Free |
| 14 June 2021 | Filippo Nardi | Novara | Cremonese | Undisclosed |
| 14 June 2021 | Alessandro Tuia | Benevento | Lecce | Free |
| 14 June 2021 | Roberto Zammarini | Pisa | Pordenone | Undisclosed |
| 15 June 2021 | Álvaro Morata | Atlético Madrid | Juventus | Loan |
| 15 June 2021 | Senna Miangué | Cagliari | Cercle Brugge | Loan |
| 15 June 2021 | Antonio Palumbo | Sampdoria | Ternana | Undisclosed |
| 16 June 2021 | Salvatore Elia | Atalanta | Perugia | Undisclosed |
| 17 June 2021 | Nicola Dalmonte | Genoa | Vicenza | Undisclosed |
| 17 June 2021 | Gianluigi Buffon | Juventus | Parma | Free |
| 17 June 2021 | Dor Peretz | Maccabi Tel Aviv | Venezia | Free |
| 17 June 2021 | Fikayo Tomori | Chelsea | Milan | Undisclosed |
| 18 June 2021 | Lukas Klitten | AaB | Frosinone | Free |
| 18 June 2021 | Stanko Jurić | Hajduk Split | Parma | Undisclosed |
| 19 June 2021 | Kiril Despodov | Cagliari | Ludogorets | Undisclosed |
| 21 June 2021 | Jaromír Zmrhal | Brescia | Slovan Bratislava | Undisclosed |
| 21 June 2021 | Diego Laxalt | Milan | Dynamo Moscow | Undisclosed |
| 22 June 2021 | Joakim Milli | Lecce | Virtus Francavilla | Undisclosed |
| 22 June 2021 | Hakan Çalhanoğlu | Milan | Inter | Free |
| 22 June 2021 | Rayyan Baniya | Verona | Fatih Karagümrük | Undisclosed |
| 22 June 2021 | Marlon | Sassuolo | Shakhtar Donetsk | Undisclosed |
| 22 June 2021 | Marco Olivieri | Juventus | Lecce | Loan |
| 23 June 2021 | Alexis Blin | Amiens | Lecce | Undisclosed |
| 23 June 2021 | Kevin-Prince Boateng | Monza | Hertha BSC | Free |
| 23 June 2021 | Nicolás González | VfB Stuttgart | Fiorentina | Undisclosed |
| 24 June 2021 | Wylan Cyprien | Parma | Nantes | Loan |
| 24 June 2021 | Nicky Beloko | Fiorentina | Neuchâtel Xamax | Undisclosed |
| 25 June 2021 | Alex Cordaz | Crotone | Inter | Undisclosed |
| 25 June 2021 | Andrea Danzi | Verona | Cittadella | Undisclosed |
| 27 June 2021 | Adrian Benedyczak | Pogoń Szczecin | Parma | Undisclosed |
| 28 June 2021 | Tyronne Ebuehi | Benfica | Venezia | Loan |
| 28 June 2021 | Svante Ingelsson | Udinese | Hansa Rostock | Undisclosed |
| 28 June 2021 | Gianluca Saro | Pro Vercelli | Crotone | Undisclosed |
| 29 June 2021 | Jonathan Jorge | Hammarby | Venezia | Loan |
| 29 June 2021 | Michele Di Gregorio | Inter | Monza | Loan |
| 30 June 2021 | Lorenzo Paolucci | Reggina | Union SG | Undisclosed |
| 30 June 2021 | Brynjar Ingi Bjarnason | KA | Lecce | Undisclosed |
| 30 June 2021 | Ignacio Pussetto | Watford | Udinese | Loan |
| 30 June 2021 | Tommaso D'Orazio | Bari | Ascoli | Loan |
| 30 June 2021 | Lorenzo Gavioli | Inter | Reggina | Loan |
| 30 June 2021 | Rigoberto Rivas | Inter | Reggina | Undisclosed |
| 1 July 2021 | Simone Perilli | Pisa | Brescia | Free |
| 1 July 2021 | Mattéo Tramoni | Cagliari | Brescia | Loan |
| 1 July 2021 | Davis Mensah | Triestina | Pordenone | Undisclosed |
| 1 July 2021 | Aleksander Buksa | Wisła Kraków | Genoa | Free |
| 2 July 2021 | Juan Musso | Udinese | Atalanta | Undisclosed |
| 2 July 2021 | Musa Barrow | Atalanta | Bologna | Undisclosed |
| 2 July 2021 | Adama Soumaoro | Lille | Bologna | Undisclosed |
| 2 July 2021 | Kevin Bonifazi | S.P.A.L. | Bologna | Undisclosed |
| 2 July 2021 | Victor De Lucia | Feralpisalò | Frosinone | Free |
| 2 July 2021 | Hamza Haoudi | Livorno | Frosinone | Free |
| 3 July 2021 | Sydney van Hooijdonk | NAC Breda | Bologna | Undisclosed |
| 3 July 2021 | Kevin Strootman | OM | Cagliari | Loan |
| 3 July 2021 | Etrit Berisha | S.P.A.L. | Torino | Free |
| 3 July 2021 | Giacomo Zanotel | Pordenone | Torino | Free |
| 3 July 2021 | Marco Varnier | Atalanta | Como | Loan |
| 3 July 2021 | Alexander Satariano | Sliema Wanderers | Frosinone | Free |
| 4 July 2021 | Cengiz Ünder | Roma | Marseille | Loan |
| 4 July 2021 | Jean Freddi Greco | Torino | Pordenone | Undisclosed |
| 5 July 2021 | Kevin Diks | Fiorentina | Copenhagen | Undisclosed |
| 5 July 2021 | Petko Hristov | Fiorentina | Spezia | Undisclosed |
| 5 July 2021 | Davide Agazzi | Vicenza | Ternana | Free |
| 5 July 2021 | Nicholas Ioannou | Nottingham Forest | Como | Loan |
| 6 July 2021 | Achraf Hakimi | Inter | Paris Saint-Germain | €70m |
| 6 July 2021 | Enrico Guarna | Reggina | Ascoli | Undisclosed |
| 7 July 2021 | Martin Hongla | Antwerp | Verona | Loan |
| 7 July 2021 | Alessandro Farroni | Reggina | Vis Pesaro | Loan |
| 8 July 2021 | Matija Boben | Livorno | Ternana | Undisclosed |
| 8 July 2021 | Pau López | Roma | Marseille | Loan |
| 8 July 2021 | Sandro Tonali | Brescia | Milan | Undisclosed |
| 9 July 2021 | Manuel Gasparini | Udinese | Pro Vercelli | Loan |
| 9 July 2021 | Luca Mazzitelli | Sassuolo | Monza | Undisclosed |
| 9 July 2021 | Magnus Warming | Lyngby Boldklub | Torino | Undisclosed |
| 12 July 2021 | Lorenzo Andrenacci | Brescia | Genoa | Free |
| 12 July 2021 | Emmanuel Latte Lath | Atalanta | S.P.A.L. | Loan |
| 12 July 2021 | Luca Vido | Atalanta | Cremonese | Loan |
| 12 July 2021 | Marco Carnesecchi | Atalanta | Cremonese | Loan |
| 12 July 2021 | Caleb Okoli | Atalanta | Cremonese | Loan |
| 12 July 2021 | Lorenzo Bernasconi | Cremonese | Atalanta | 2-year loan |
| 12 July 2021 | Rodrigo De Paul | Udinese | Atlético Madrid | Undisclosed |
| 12 July 2021 | Piotr Parzyszek | Frosinone | Pogoń Szczecin | Loan |
| 12 July 2021 | Mattia Valoti | S.P.A.L. | Monza | Loan |
| 12 July 2021 | Michele Cavion | Ascoli | Salernitana | Free |
| 13 July 2021 | Rui Patrício | Wolverhampton | Roma | €11,5m |
| 13 July 2021 | Zinho Vanheusden | Standard Liège | Inter | Undisclosed |
| 13 July 2021 | Sebastiano Esposito | Inter | Basel | Loan |
| 13 July 2021 | Musa Juwara | Bologna | Crotone | Loan |
| 13 July 2021 | Francesco Lisi | Pisa | Perugia | Loan |
| 13 July 2021 | João Mário | Inter | Benfica | Free |
| 13 July 2021 | Vasco Regini | Sampdoria | Reggina | Free |
| 13 July 2021 | Alessandro Micai | Salernitana | Reggina | Loan |
| 13 July 2021 | Federico Ricci | Sassuolo | Reggina | Undisclosed |
| 13 July 2021 | Stefano Turati | Sassuolo | Reggina | Loan |
| 13 July 2021 | Filippo Scaglia | Monza | Como | Undisclosed |
| 14 July 2021 | Andreaw Gravillon | Inter | Reims | Loan |
| 14 July 2021 | Lorenzo Pirola | Inter | Monza | Loan |
| 14 July 2021 | Nicholas Bonfanti | Inter | Modena | Undisclosed |
| 14 July 2021 | Simone Mazzocchi | Atalanta | Ternana | Loan |
| 14 July 2021 | Boris Radunović | Atalanta | Ternana | Undisclosed |
| 14 July 2021 | Christian Sussi | Arezzo | Pisa | Free |
| 14 July 2021 | Nicolò Bruschi | Fiorenzuola | Pisa | Free |
| 14 July 2021 | Giacomo Calò | Genoa | Benevento | Loan |
| 15 July 2021 | Filippo Serena | Venezia | Grosseto | Loan |
| 15 July 2021 | Pietro Beruatto | Juventus | Pisa | Loan |
| 15 July 2021 | Idrissa Touré | Juventus | Pisa | Loan |
| 15 July 2021 | Damiano Franco | Lazio | Reggina | Free |
| 15 July 2021 | Nikola Vasic | Reggina | Vasalund | Loan |
| 15 July 2021 | Tanner Tessmann | Dallas | Venezia | Undisclosed |
| 15 July 2021 | Destiny Udogie | Verona | Udinese | Loan |
| 15 July 2021 | Luca Crecco | Pescara | Vicenza | Loan |
| 15 July 2021 | Frank Tsadjout | Milan | Pordenone | Loan |
| 15 July 2021 | Nicolò Cambiaghi | Atalanta | Pordenone | Loan |
| 15 July 2021 | Jean Lambert Evans | Crotone | Pau | Undisclsoed |
| 15 July 2021 | Stefano Pettinari | Lecce | Ternana | Free |
| 15 July 2021 | Emanuele Suagher | Ternana | FeralpiSalò | Loan |
| 15 July 2021 | Aristidi Kolaj | Sassuolo | Alessandria | Undisclosed |
| 16 July 2021 | Felipe Anderson | West Ham | Lazio | Undisclosed |
| 16 July 2021 | Nils Arvidsson | Helsingborg | Venezia | Loan |
| 16 July 2021 | Karim Laribi | Verona | Reggina | Undisclosed |
| 16 July 2021 | Marco Calderoni | Lecce | Vicenza | Undisclosed |
| 16 July 2021 | Cristian Dell'Orco | Sassuolo | Perugia | Undisclosed |
| 16 July 2021 | Hjörtur Hermannsson | Brøndby | Pisa | Free |
| 16 July 2021 | Emmanuel Gyabuaa | Atalanta | Perugia | Loan |
| 16 July 2021 | Luca Valzania | Atalanta | Cremonese | Loan |
| 16 July 2021 | Lorenzo Peli | Atalanta | Como | Loan |
| 16 July 2021 | Ionuț Nedelcearu | AEK Athens | Crotone | Loan |
| 17 July 2021 | Olivier Giroud | Chelsea | Milan | Undisclosed |
| 17 July 2021 | Paweł Jaroszyński | Genoa | Salernitana | Loan |
| 17 July 2021 | Alberto Paleari | Genoa | Benevento | Loan |
| 17 July 2021 | Francesco Bardi | Frosinone | Bologna | Undisclosed |
| 17 July 2021 | Federico Ravaglia | Bologna | Frosinone | Loan |
| 17 July 2021 | Federico Proia | Cittadella | Vicenza | Undisclosed |
| 17 July 2021 | Anton Krešić | Atalanta | Rijeka | Loan |
| 17 July 2021 | Gabriel Lunetta | Atalanta | Alessandria | Loan |
| 17 July 2021 | Diego Fabbrini | Dinamo București | Ascoli | Free |
| 18 July 2021 | Fodé Ballo-Touré | Monaco | Milan | Undisclosed |
| 18 July 2021 | Giorgio Altare | Genoa | Cagliari | Undisclosed |
| 18 July 2021 | Aljaz Tavcar | Bilje | Ascoli | Undisclosed |
| 19 July 2021 | Nadir Zortea | Atalanta | Salernitana | Loan |
| 19 July 2021 | Bryan Dabo | Benevento | Çaykur Rizespor | Undisclosed |
| 19 July 2021 | Julián Illanes | Fiorentina | Pescara | Undisclosed |
| 19 July 2021 | Edoardo Pierozzi | Fiorentina | Alessandria | Undisclosed |
| 20 July 2021 | Salvatore Elia | Atalanta | Benevento | Loan |
| 20 July 2021 | Rodrigo Guth | Atalanta | NEC Nijmegen | Loan |
| 20 July 2021 | Justin Kluivert | Roma | Nice | Loan |
| 20 July 2021 | Marco Silvestri | Verona | Udinese | Undisclosed |
| 20 July 2021 | Lorenzo Montipò | Benevento | Verona | Loan |
| 20 July 2021 | Andrea Adamoli | Empoli | Cesena | Loan |
| 20 July 2021 | Petar Stojanović | Dinamo Zagreb | Empoli | Loan |
| 20 July 2021 | Leonardo Loria | Pisa | Monopoli | Loan |
| 20 July 2021 | Zinho Vanheusden | Inter | Genoa | Loan |
| 21 July 2021 | Felipe Vizeu | Udinese | Yokohama | Loan |
| 21 July 2021 | Dalbert | Inter | Cagliari | Loan |
| 21 July 2021 | Tomasz Kupisz | Salernitana | Pordenone | Undisclosed |
| 21 July 2021 | Joel Obi | Chievo | Salernitana | Free |
| 21 July 2021 | Edoardo Masciangelo | Pescara | Benevento | Loan |
| 21 July 2021 | Stefano Gori | Juventus | Como | Loan |
| 21 July 2021 | Francesco Belli | Pisa | Bari | Loan |
| 21 July 2021 | Filippo Berra | Bari | Pisa | Undisclosed |
| 21 July 2021 | Lorenzo Lucca | Palermo | Pisa | Undisclosed |
| 22 July 2021 | Kelvin Amian | Toulouse | Spezia | Undisclosed |
| 22 July 2021 | Jacopo Pellegrini | Sassuolo | Pordenone | Loan |
| 22 July 2021 | Leonardo Sernicola | Sassuolo | Cremonese | Loan |
| 22 July 2021 | Federico Mazzarani | Ternana | Pro Sesto | Loan |
| 23 July 2021 | Stefan Strandberg | Ural Yekaterinburg | Salernitana | Free |
| 23 July 2021 | Giuseppe Fella | Salernitana | Palermo | Loan |
| 23 July 2021 | Emanuele Matteucci | Empoli | Pontedera | Loan |
| 23 July 2021 | Szymon Żurkowski | Fiorentina | Empoli | Loan |
| 23 July 2021 | Soualiho Meïté | Torino | Benfica | Undisclosed |
| 23 July 2021 | Andrea Poli | Bologna | Antalyaspor | Undisclosed |
| 23 July 2021 | Marco Pompetti | Inter | Pescara | Loan |
| 23 July 2021 | Luca Coccolo | Juventus | S.P.A.L. | Loan |
| 23 July 2021 | Pedro Pereira | Benfica | Monza | Loan |
| 23 July 2021 | Silvio Colella | Lecce | Bitonto | Loan |
| 24 July 2021 | Antonio Candela | Genoa | Cesena | Loan |
| 24 July 2021 | Orji Okwonkwo | Bologna | Cittadella | Loan |
| 24 July 2021 | Pierluigi Gollini | Atalanta | Tottenham | Loan |
| 24 July 2021 | Giacomo Siniega | Empoli | Grosseto | Loan |
| 24 July 2021 | Davide Merola | Empoli | Foggia | Loan |
| 24 July 2021 | Jens Odgaard | Sassuolo | RKC Waalwijk | Loan |
| 26 July 2021 | Mamadou Coulibaly | Udinese | Salernitana | Loan |
| 26 July 2021 | Francesco Donati | Empoli | Juve Stabia | Loan |
| 27 July 2021 | Giuseppe Pezzella | Parma | Atalanta | Loan |
| 27 July 2021 | Christian Capone | Atalanta | Ternana | Loan |
| 27 July 2021 | Gabriele Capanni | Milan | Ternana | Loan |
| 27 July 2021 | Alexis Ferrante | Ternana | Foggia | Loan |
| 27 July 2021 | Zito Luvumbo | Cagliari | Como | Loan |
| 27 July 2021 | Samuele Mulattieri | Inter | Crotone | Loan |
| 27 July 2021 | Gabriel Meli | Empoli | Südtirol | Loan |
| 27 July 2021 | Matteo Ruggeri | Atalanta | Salernitana | Loan |
| 28 July 2021 | Alessio Zerbin | Napoli | Frosinone | Loan |
| 28 July 2021 | Gabriel Charpentier | Genoa | Frosinone | Loan |
| 28 July 2021 | Përparim Hetemaj | Benevento | Reggina | Free |
| 28 July 2021 | Andrea Seculin | Chievo | S.P.A.L. | Free |
| 28 July 2021 | Marko Pjaca | Juventus | Torino | Loan |
| 28 July 2021 | Álvaro Martí | Espanyol | Lecce | Undisclosed |
| 29 July 2021 | Arturo Calabresi | Bologna | Lecce | Undisclosed |
| 29 July 2021 | Valentin Gendrey | Amiens | Lecce | Undisclosed |
| 29 July 2021 | Valerio Mantovani | Salernitana | Alessandria | Undisclosed |
| 29 July 2021 | Tibo Persyn | Inter | Club Brugge | Loan |
| 30 July 2021 | Ludovico D'Orazio | Roma | S.P.A.L. | Undisclosed |
| 30 July 2021 | Mirko Antonucci | Roma | Cittadella | Undisclosed |
| 30 July 2021 | Leonard Zuta | Lecce | Vålerenga | Undisclosed |
| 30 July 2021 | Gianluca Frabotta | Juventus | Verona | Loan |
| 30 July 2021 | Riccardo Marchizza | Sassuolo | Empoli | Loan |
| 30 July 2021 | Arnór Sigurðsson | CSKA Moscow | Venezia | Loan |
| 30 July 2021 | Filip Bradarić | Cagliari | Al Ahli | Loan |
| 31 July 2021 | Matteo Lovato | Verona | Atalanta | Undisclosed |
| 31 July 2021 | Niccolò Chiorra | Empoli | Taranto | Loan |
| 31 July 2021 | Lorenzo Colombo | Milan | S.P.A.L. | Loan |
| 31 July 2021 | Lassana Coulibaly | Angers | Salernitana | Free |
| 31 July 2021 | Wajdi Kechrida | ÉS Sahel | Salernitana | Free |
| 31 July 2021 | Vittorio Parigini | Genoa | Como | Loan |
| 31 July 2021 | Patrick Ciurria | Pordenone | Monza | Undisclosed |
| 2 August 2021 | Eldor Shomurodov | Genoa | Roma | €17,5m |
| 2 August 2021 | Lucas Felippe | Verona | Farense | Undisclosed |
| 3 August 2021 | Salvatore Sirigu | Torino | Genoa | Free |
| 3 August 2021 | Hamza El Kaouakibi | Bologna | Pordenone | Undisclosed |
| 3 August 2021 | Francesco Orlando | Salernitana | Alessandria | Loan |
| 3 August 2021 | Juan Manuel Ramos | Spezia | Peñarol | Undisclosed |
| 3 August 2021 | Federico Bonazzoli | Sampdoria | Salernitana | Undisclosed |
| 3 August 2021 | Franco Ferrari | Napoli | Pescara | Loan |
| 3 August 2021 | Eugenio D'Ursi | Napoli | Pescara | Loan |
| 3 August 2021 | Michele Marconi | Pisa | Alessandria | Undisclosed |
| 3 August 2021 | Simone Benedetti | Pisa | Alessandria | Undisclosed |
| 3 August 2021 | Stefano Scognamillo | Alessandria | Catanzaro | Undisclosed |
| 3 August 2021 | Eric Botteghin | Feyenoord | Ascoli | Free |
| 4 August 2021 | Francesco Rillo | Benevento | Teramo | Loan |
| 4 August 2021 | Marco Cuccurullo | Benevento | Teramo | Undisclosed |
| 4 August 2021 | Filip Stanković | Inter | Volendam | Loan |
| 4 August 2021 | Marko Arnautović | Shanghai Port | Bologna | Undisclosed |
| 4 August 2021 | Mariusz Stępiński | Verona | Aris Limassol | Loan |
| 4 August 2021 | Guido Marilungo | Ternana | Pescara | Loan |
| 4 August 2021 | Frederik Sørensen | Pescara | Ternana | Undisclosed |
| 4 August 2021 | Tommaso Cancellotti | Perugia | Pescara | Undisclosed |
| 4 August 2021 | Juraj Kucka | Parma | Watford | Loan |
| 5 August 2021 | Giovanni Volpicelli | Benevento | Paganese | Undisclosed |
| 5 August 2021 | Francesco Perlingieri | Benevento | Paganese | Loan |
| 5 August 2021 | Iacopo Cernigoi | Salernitana | Seregno | Loan |
| 5 August 2021 | Lazar Samardžić | RB Leipzig | Udinese | Undisclosed |
| 5 August 2021 | Christian Langella | Pisa | Monopoli | Loan |
| 5 August 2021 | Christian Sussi | Pisa | Paganese | Loan |
| 5 August 2021 | Maxime Leverbe | Chievo | Pisa | Free |
| 5 August 2021 | Davide Di Quinzio | Alessandria | Pisa | Undisclosed |
| 5 August 2021 | Andrea Beghetto | Pisa | Alessandria | Loan |
| 5 August 2021 | Alessandro Salvi | Frosinone | Ascoli | Free |
| 6 August 2021 | Gennaro Acampora | Spezia | Benevento | Free |
| 6 August 2021 | Vincenzo Fiorillo | Pescara | Salernitana | Undisclosed |
| 6 August 2021 | Merih Demiral | Juventus | Atalanta | Loan |
| 6 August 2021 | Cristian Romero | Juventus | Atalanta | €16m |
| 6 August 2021 | Cristian Romero | Atalanta | Tottenham | Loan |
| 6 August 2021 | Amato Ciciretti | Napoli | Pordenone | Undisclosed |
| 6 August 2021 | Elvis Kabashi | Renate | Como | Undisclosed |
| 7 August 2021 | Ebrima Colley | Atalanta | Spezia | Loan |
| 7 August 2021 | Hernani | Parma | Genoa | Loan |
| 7 August 2021 | Pasquale Schiattarella | Benevento | Parma | Undisclosed |
| 7 August 2021 | Caleb Ekuban | Trabzonspor | Genoa | Undisclosed |
| 7 August 2021 | Abou Ba | Nantes | Alessandria | Loan |
| 8 August 2021 | Viktor Kovalenko | Atalanta | Spezia | Loan |
| 8 August 2021 | Matías Viña | Palmeiras | Roma | €13m |
| 8 August 2021 | Nicholas Rizzo | Genoa | Virton | Loan |
| 9 August 2021 | Mattia Caldara | Milan | Venezia | Loan |
| 9 August 2021 | Ardian Ismajli | Spezia | Empoli | Undisclosed |
| 9 August 2021 | Dimitris Nikolaou | Empoli | Spezia | Undisclosed |
| 9 August 2021 | Samuel Mráz | Empoli | Spezia | Undisclosed |
| 9 August 2021 | Gianluca Busio | Sporting Kansas City | Venezia | Undisclosed |
| 9 August 2021 | Claud Adjapong | Sassuolo | Reggina | Loan |
| 9 August 2021 | Filip Jagiełło | Genoa | Brescia | Loan |
| 9 August 2021 | Montassar Talbi | Benevento | Rubin Kazan | Loan |
| 10 August 2021 | Riccardo Boscolo Chio | Inter | Imolese | Loan |
| 10 August 2021 | Gaetano Oristanio | Inter | Volendam | Loan |
| 10 August 2021 | Ettore Gliozzi | Monza | Como | Undisclosed |
| 10 August 2021 | Jens Petter Hauge | Milan | Eintracht Frankfurt | Loan |
| 10 August 2021 | Andreas Cornelius | Parma | Trabzonspor | Undisclosed |
| 10 August 2021 | Felipe Curcio | Salernitana | Padova | Undisclosed |
| 10 August 2021 | Nicolò Armini | Lazio | Piacenza | Loan |
| 10 August 2021 | Michael Folorunsho | Napoli | Pordenone | Loan |
| 11 August 2021 | Liam Henderson | Lecce | Empoli | Undisclosed |
| 11 August 2021 | Tommaso Fantacci | Empoli | Gubbio | Loan |
| 11 August 2021 | Adrian Šemper | Chievo | Genoa | Free |
| 11 August 2021 | Alfredo Donnarumma | Brescia | Ternana | Loan |
| 11 August 2021 | Salim Diakite | Teramo | Ternana | Undisclosed |
| 11 August 2021 | Andrea Tozzo | Ternana | Teramo | Loan |
| 11 August 2021 | Yonatan Cohen | Maccabi Tel Aviv | Pisa | Undisclosed |
| 11 August 2021 | Bamba Susso | Pisa | VillaValle | Loan |
| 11 August 2021 | Andrea Cisco | Novara | Pisa | Free |
| 11 August 2021 | Matheus Henrique | Grêmio | Sassuolo | Loan |
| 11 August 2021 | Ruan | Grêmio | Sassuolo | Undisclosed |
| 11 August 2021 | Ruan | Sassuolo | Grêmio | Loan |
| 12 August 2021 | Romelu Lukaku | Inter | Chelsea | Undisclosed |
| 12 August 2021 | Stefano Moreo | Empoli | Brescia | Loan |
| 12 August 2021 | Michele Cavion | Salernitana | Brescia | Loan |
| 12 August 2021 | Reda Boultam | Salernitana | Cosenza | Loan |
| 12 August 2021 | David Okereke | Club Brugge | Venezia | Loan |
| 12 August 2021 | Oscar Linnér | Arminia Bielefeld | Brescia | Loan |
| 12 August 2021 | Ivan Ilić | Manchester City | Verona | Undisclosed |
| 12 August 2021 | Gabriel Strefezza | S.P.A.L. | Lecce | Undisclosed |
| 13 August 2021 | Patrick Cutrone | Wolverhampton | Empoli | Loan |
| 13 August 2021 | Sebastiano Luperto | Napoli | Empoli | Loan |
| 13 August 2021 | Gennaro Tutino | Napoli | Parma | Loan |
| 13 August 2021 | Félix Correia | Juventus | Parma | Loan |
| 13 August 2021 | Alessandro Vogliacco | Pordenone | Genoa | Undisclosed |
| 13 August 2021 | Alessandro Vogliacco | Genoa | Benevento | Loan |
| 13 August 2021 | Assan Seck | Pescara | Pisa | Undisclosed |
| 13 August 2021 | Gianmarco Ingrosso | Pisa | Pescara | Undisclosed |
| 13 August 2021 | Massimo Bertagnoli | Chievo | Brescia | Free |
| 13 August 2021 | Andrea Cagnano | Novara | Como | Free |
| 14 August 2021 | Edin Džeko | Roma | Inter | Undisclosed |
| 14 August 2021 | Denzel Dumfries | PSV Eindhoven | Inter | Undisclosed |
| 14 August 2021 | Radja Nainggolan | Inter | Antwerp | Free |
| 14 August 2021 | Grigoris Kastanos | Juventus | Salernitana | Loan |
| 15 August 2021 | Alessandro Tripaldelli | Cagliari | S.P.A.L. | Loan |
| 16 August 2021 | Johan Vásquez | Pumas | Genoa | Loan |
| 16 August 2021 | Elia Petrelli | Genoa | Ascoli | Loan |
| 17 August 2021 | Mirko Marić | Monza | Crotone | Loan |
| 17 August 2021 | Tammy Abraham | Chelsea | Roma | €40m |
| 17 August 2021 | Marco Tumminello | Atalanta | Reggina | Loan |
| 17 August 2021 | Pietro Rovaglia | Chievo | Ternana | Free |
| 17 August 2021 | Pietro Rovaglia | Ternana | Fermana | Loan |
| 17 August 2021 | Ľubomír Tupta | Verona | Slovan Liberec | Loan |
| 17 August 2021 | Alberto Cerri | Cagliari | Como | Loan |
| 17 August 2021 | Davide Riccardi | Lecce | Triestina | Undisclosed |
| 17 August 2021 | Christian Celesia | Torino | Alessandria | Loan |
| 18 August 2021 | Edoardo Sottini | Inter | Pistoiese | Loan |
| 18 August 2021 | Lorenzo Moretti | Inter | Pistoiese | Loan |
| 18 August 2021 | Marco Carraro | Atalanta | Cosenza | Loan |
| 18 August 2021 | Manuel Locatelli | Sassuolo | Juventus | 2-year loan |
| 18 August 2021 | Juan Jesus | Roma | Napoli | Loan |
| 18 August 2021 | Nikita Contini | Napoli | Crotone | Loan |
| 18 August 2021 | Andrea Marino | Lazio | Piacenza | Loan |
| 18 August 2021 | Simone Palombi | Lazio | Alessandria | Loan |
| 18 August 2021 | Mehdi Léris | Sampdoria | Brescia | Loan |
| 18 August 2021 | Rodrigo Palacio | Bologna | Brescia | Free |
| 18 August 2021 | Andrey Galabinov | Spezia | Reggina | Free |
| 18 August 2021 | Antonino La Gumina | Sampdoria | Como | Loan |
| 19 August 2021 | Elvis Lindqvist | Inter | Torino | Loan |
| 19 August 2021 | Simy | Crotone | Salernitana | Loan |
| 19 August 2021 | Germán Pezzella | Fiorentina | Betis | Undisclosed |
| 19 August 2021 | Aimar Sher | Hammarby | Spezia | Undisclosed |
| 19 August 2021 | Jacopo Petriccione | Crotone | Pordenone | Loan |
| 19 August 2021 | Elseid Hysaj | Napoli | Lazio | Free |
| 19 August 2021 | Luka Romero | Mallorca | Lazio | Undisclosed |
| 19 August 2021 | Nikolaos Baxevanos | Lazio | Chindia Târgoviște | Undisclosed |
| 19 August 2021 | Sergio Kalaj | Lazio | Carrarese | Undisclosed |
| 19 August 2021 | Mattia Novella | Lazio | Monopoli | Undisclosed |
| 20 August 2021 | Giacomo Pozzer | Inter | Juve Stabia | Undisclosed |
| 20 August 2021 | Luca Magazzu | Inter | Empoli | Undisclosed |
| 20 August 2021 | Thomas Schirò | Inter | Crotone | Undisclosed |
| 20 August 2021 | Sanasi Sy | Salernitana | Cosenza | Undisclosed |
| 20 August 2021 | Christian Dalle Mura | Fiorentina | Cremonese | Loan |
| 20 August 2021 | Elio Capradossi | Spezia | S.P.A.L. | Loan |
| 20 August 2021 | Jakub Jankto | Sampdoria | Getafe | Undisclosed |
| 20 August 2021 | Marco Mancosu | Lecce | S.P.A.L. | Undisclosed |
| 20 August 2021 | Danilo Giacinto Ventola | Ascoli | Virtus Francavilla | Loan |
| 21 August 2021 | Alessandro Florenzi | Roma | Milan | Loan |
| 21 August 2021 | Alberto Grassi | Parma | Cagliari | Loan |
| 21 August 2021 | Matija Nastasić | Schalke 04 | Fiorentina | Undisclosed |
| 21 August 2021 | Christian Kouamé | Fiorentina | Anderlecht | Loan |
| 21 August 2021 | Leonardo Ubaldi | Pisa | Pistoiese | Loan |
| 22 August 2021 | William Bianda | Roma | Nancy | Loan |
| 23 August 2021 | Pol Lirola | Fiorentina | OM | Undisclosed |
| 23 August 2021 | Andri Baldursson | Bologna | Copenhagen | Loan |
| 23 August 2021 | Bruno Martella | Brescia | Ternana | Undisclosed |
| 23 August 2021 | Giacomo Manzari | Sassuolo | Frosinone | 2-year loan |
| 23 August 2021 | Giuseppe Barone | Unattached | Ascoli | Free |
| 24 August 2021 | Samuel Di Carmine | Verona | Cremonese | Undisclosed |
| 24 August 2021 | Thomas Henry | OH Leuven | Venezia | Undisclosed |
| 24 August 2021 | Ante Ćorić | Roma | Zürich | Loan |
| 24 August 2021 | Davide Zappacosta | Chelsea | Atalanta | Undisclosed |
| 24 August 2021 | David Heidenreich | Atalanta | S.P.A.L. | Loan |
| 24 August 2021 | Jacopo Da Riva | Atalanta | S.P.A.L. | Loan |
| 24 August 2021 | Lennart Czyborra | Genoa | Arminia Bielefeld | Loan |
| 24 August 2021 | Mattia D'Agostino | Ascoli | Monopoli | Loan |
| 24 August 2021 | Andrea De Paoli | Monopoli | Ascoli | Loan |
| 25 August 2021 | Boško Šutalo | Atalanta | Verona | Loan |
| 25 August 2021 | Alexandre Pimenta | Venezia | Leixões | Loan |
| 25 August 2021 | Andrea Pinamonti | Inter | Empoli | Loan |
| 25 August 2021 | Lorenzo Colombini | Spezia | Giana Erminio | Loan |
| 25 August 2021 | Janis Antiste | Giana Erminio | Spezia | Undisclosed |
| 25 August 2021 | Lyanco | Torino | Southampton | Undisclosed |
| 25 August 2021 | Toma Bašić | Bordeaux | Lazio | Undisclosed |
| 25 August 2021 | Lucas Torreira | Arsenal | Fiorentina | Loan |
| 25 August 2021 | Nahuel Estévez | Estudiantes | Crotone | Loan |
| 25 August 2021 | Tommaso Milanese | Roma | Alessandria | Loan |
| 25 August 2021 | Stefano Denswil | Bologna | Trabzonspor | Loan |
| 26 August 2021 | Isaac Success | Watford | Udinese | Undisclosed |
| 26 August 2021 | Joaquín Correa | Lazio | Inter | Loan |
| 26 August 2021 | Giovanni Simeone | Cagliari | Verona | Loan |
| 26 August 2021 | Arthur Theate | Oostende | Bologna | Loan |
| 26 August 2021 | Manuel De Luca | Sampdoria | Perugia | Loan |
| 26 August 2021 | Atanas Iliev | Botev Plovdiv | Ascoli | Undisclosed |
| 26 August 2021 | Franco Zuculini | Defensor Sporting | S.P.A.L. | Free |
| 26 August 2021 | Karim Zedadka | Napoli | Charleroi | Loan |
| 26 August 2021 | Filippo Neri | Livorno | Venezia | Free |
| 27 August 2021 | Lorenzo Tonelli | Sampdoria | Empoli | Undisclosed |
| 27 August 2021 | Godfred Donsah | Bologna | Crotone | Free |
| 27 August 2021 | Fallou Sarr | Bologna | Cremonese | Undisclosed |
| 27 August 2021 | Žan Celar | Roma | Lugano | Undisclosed |
| 27 August 2021 | Cristiano Ronaldo | Juventus | Manchester United | €15m |
| 27 August 2021 | Martin Palumbo | Udinese | Juventus U23 | Loan |
| 27 August 2021 | Nehuén Paz | Bologna | Crotone | Undisclosed |
| 27 August 2021 | Valentin Antov | CSKA Sofia | Monza | Loan |
| 27 August 2021 | Ádám Nagy | Bristol City | Pisa | Undisclosed |
| 27 August 2021 | Thomas Alberti | Pisa | Fidelis Andria | Loan |
| 27 August 2021 | Georgi Tunjov | S.P.A.L. | Carrarese | Loan |
| 27 August 2021 | Raffaele Celia | Sassuolo | S.P.A.L. | Undisclosed |
| 27 August 2021 | Alberto Pomini | Venezia | S.P.A.L. | Free |
| 27 August 2021 | Tommaso Pobega | Milan | Torino | Loan |
| 27 August 2021 | Emil Holm | SønderjyskE | Spezia | Undisclosed |
| 27 August 2021 | Ognjen Stijepović | Sampdoria | Spezia | Undisclosed |
| 27 August 2021 | Ognjen Stijepović | Spezia | Pistoiese | Loan |
| 27 August 2021 | Simone Canestrelli | Empoli | Crotone | Loan |
| 27 August 2021 | Antonio Barreca | Monaco | Lecce | Loan |
| 27 August 2021 | Francesco Di Mariano | Venezia | Lecce | Undisclosed |
| 27 August 2021 | Óttar Magnús Karlsson | Venezia | Siena | Loan |
| 27 August 2021 | Riccardo Moreo | Cosenza | Pergolettese | Undisclosed |
| 28 August 2021 | Elias Cobbaut | Anderlecht | Parma | Loan |
| 28 August 2021 | Nehuén Pérez | Atlético Madrid | Udinese | Loan |
| 28 August 2021 | Cristo González | Udinese | Valladolid | Loan |
| 28 August 2021 | Álvaro Odriozola | Real Madrid | Fiorentina | Loan |
| 28 August 2021 | Michele Vano | Perugia | Pistoiese | Loan |
| 28 August 2021 | Giovanni Di Noia | Perugia | Fidelis Andria | Loan |
| 28 August 2021 | Luca Matarese | Frosinone | Imolese | Loan |
| 28 August 2021 | Mauro Vigorito | Lecce | Cosenza | Undisclosed |
| 28 August 2021 | Nicholas Galazzi | Venezia | Triestina | Loan |
| 29 August 2021 | Arkadiusz Reca | Atalanta | Spezia | Loan |
| 30 August 2021 | Mario Gargiulo | Cittadella | Lecce | Undisclosed |
| 30 August 2021 | Kastriot Dermaku | Parma | Lecce | Undisclosed |
| 30 August 2021 | Leandro Sanca | Braga | Spezia | Undisclosed |
| 30 August 2021 | Leandro Sanca | Spezia | Casa Pia | Loan |
| 30 August 2021 | Alessandro Bordin | Spezia | Fidelis Andria | Undisclosed |
| 30 August 2021 | Mehdi Bourabia | Sassuolo | Spezia | Loan |
| 30 August 2021 | Mikael Egill Ellertsson | S.P.A.L. | Spezia | Undisclosed |
| 30 August 2021 | Mikael Egill Ellertsson | Spezia | S.P.A.L. | Loan |
| 30 August 2021 | Teun Koopmeiners | AZ Alkmaar | Atalanta | Loan |
| 30 August 2021 | Karlo Lulić | Slaven Belupo | Frosinone | Loan |
| 30 August 2021 | Matteo Ricci | Spezia | Frosinone | Free |
| 30 August 2021 | Mario De Marino | Venezia | Fidelis Andria | Loan |
| 30 August 2021 | Tiémoué Bakayoko | Chelsea | Milan | Loan |
| 30 August 2021 | Sofian Kiyine | Lazio | Venezia | Loan |
| 30 August 2021 | Stefano Cester | Inter | Vicenza | Undisclosed |
| 30 August 2021 | Woyo Coulibaly | Le Havre | Parma | Undisclosed |
| 30 August 2021 | Djavan Anderson | Lazio | Cosenza | Loan |
| 30 August 2021 | Kaique Rocha | Sampdoria | Internacional | 2-year loan |
| 30 August 2021 | Lukáš Haraslín | Sassuolo | Sparta Prague | Loan |
| 31 August 2021 | Edoardo Vergani | Inter | Salernitana | Undisclosed |
| 31 August 2021 | David Wieser | Inter | Bologna | Loan |
| 31 August 2021 | Alessandro Cortinovis | Atalanta | Reggina | Loan |
| 31 August 2021 | Leroy Abanda | Milan | Boulogne | Loan |
| 31 August 2021 | Moise Kean | Everton | Juventus | 2-year loan |
| 31 August 2021 | Filippo Delli Carri | Juventus | Salernitana | Loan |
| 31 August 2021 | Filippo Ranocchia | Juventus | Vicenza | Loan |
| 31 August 2021 | Enrico Del Prato | Atalanta | Parma | Loan |
| 31 August 2021 | Ange-Yoan Bonny | Châteauroux | Parma | Undisclosed |
| 31 August 2021 | Mirza Hasanbegović | Venezia | Gorica | Loan |
| 31 August 2021 | Luca Vignali | Spezia | Como | Loan |
| 31 August 2021 | Kevin Agudelo | Genoa | Spezia | Loan |
| 31 August 2021 | Kleis Bozhanaj | Empoli | Spezia | Undisclosed |
| 31 August 2021 | Kleis Bozhanaj | Spezia | Casa Pia | Loan |
| 31 August 2021 | David Strelec | Slovan Bratislava | Spezia | Undisclosed |
| 31 August 2021 | Jakub Kiwior | Žilina | Spezia | Undisclosed |
| 31 August 2021 | Rey Manaj | Barcelona | Spezia | Loan |
| 31 August 2021 | Mattia Zaccagni | Verona | Lazio | Loan |
| 31 August 2021 | Angelo Ndrecka | Lazio | Teramo | Loan |
| 31 August 2021 | Angelo Ndrecka | Lazio | Teramo | Loan |
| 31 August 2021 | Tiago Casasola | Lazio | Frosinone | Loan |
| 31 August 2021 | Felipe Caicedo | Lazio | Genoa | Undisclosed |
| 31 August 2021 | Mohamed Farès | Lazio | Genoa | Loan |
| 31 August 2021 | Emanuele Cicerelli | Lazio | Frosinone | Loan |
| 31 August 2021 | Lucien Agoumé | Inter | Brest | Loan |
| 31 August 2021 | Valentino Lazaro | Inter | Benfica | Loan |
| 31 August 2021 | Étienne Kinkoue | Inter | Olympiacos | Undisclosed |
| 31 August 2021 | Riccardo Ciervo | Roma | Sampdoria | Loan |
| 31 August 2021 | Jeison Murillo | Sampdoria | Vigo | Loan |
| 31 August 2021 | Luca Marrone | Crotone | Monza | Undisclosed |
| 31 August 2021 | Andrea Favilli | Genoa | Monza | Loan |
| 31 August 2021 | Armando Anastasio | Monza | Reggiana | Loan |
| 31 August 2021 | Marco Fossati | Monza | Hajduk Split | Undisclosed |
| 31 August 2021 | Stefano Negro | Monza | Triestina | Undisclosed |
| 31 August 2021 | Andrea Palazzi | Monza | Alessandria | Undisclosed |
| 31 August 2021 | André-Frank Zambo Anguissa | Fulham | Napoli | Loan |
| 31 August 2021 | Zinédine Machach | Napoli | Honvéd | Loan |
| 31 August 2021 | Gianluca Gaetano | Napoli | Cremonese | Loan |
| 31 August 2021 | Luca Palmiero | Napoli | Cosenza | Loan |
| 31 August 2021 | Julian Kristoffersen | Salernitana | Cosenza | Loan |
| 31 August 2021 | Steeve-Mike Eyango | Genoa | Cosenza | Loan |
| 31 August 2021 | Mario Šitum | Reggina | Cosenza | Loan |
| 31 August 2021 | Roberto Pirrello | Empoli | Cosenza | Loan |
| 31 August 2021 | Luca Pandolfi | Turris | Cosenza | Undisclosed |
| 31 August 2021 | Vincenzo Millico | Torino | Cosenza | Loan |
| 31 August 2021 | Samir Ujkani | Torino | Empoli | Free |
| 31 August 2021 | Federico Di Francesco | S.P.A.L. | Empoli | Loan |
| 31 August 2021 | Alberto Brignoli | Empoli | Panathinaikos | Loan |
| 31 August 2021 | Kevin Piscopo | Empoli | S.P.A.L. | Loan |
| 31 August 2021 | Giovanni Crociata | Empoli | S.P.A.L. | Loan |
| 31 August 2021 | Francesco Caputo | Sassuolo | Sampdoria | Loan |
| 31 August 2021 | Radu Drăgușin | Juventus | Sampdoria | Loan |
| 31 August 2021 | Mohamed Ihattaren | PSV Eindhoven | Juventus | Loan |
| 31 August 2021 | Mohamed Ihattaren | Juventus | Sampdoria | Loan |
| 31 August 2021 | Gianluca Caprari | Sampdoria | Verona | Loan |
| 31 August 2021 | Marco Frediani | Alessandria | Fermana | Undisclosed |
| 31 August 2021 | Edoardo Blondett | Alessandria | Fermana | Undisclosed |
| 31 August 2021 | Umberto Eusepi | Alessandria | Juve Stabia | Loan |
| 31 August 2021 | Francesco Giorno | Alessandria | Triestina | Loan |
| 31 August 2021 | Simone Andrea Ganz | Ascoli | Lecco | Loan |
| 31 August 2021 | Amine Ghazoini | Ascoli | Virton | Loan |
| 31 August 2021 | Gian Filippo Felicioli | Venezia | Ascoli | Loan |
| 31 August 2021 | Abdoulaye Touré | Nantes | Genoa | Undisclosed |
| 31 August 2021 | Nikola Maksimović | Napoli | Genoa | Free |
| 31 August 2021 | Ethan Ampadu | Chelsea | Venezia | Loan |
| 31 August 2021 | Jack de Vries | Philadelphia Union | Venezia | Loan |
| 31 August 2021 | Ridgeciano Haps | Feyenoord | Venezia | Undisclosed |
| 31 August 2021 | Anthony Taugourdeau | Venezia | Vicenza | Undisclosed |
| 31 August 2021 | Eddie Salcedo | Genoa | Spezia | Loan |
| 31 August 2021 | Sam Lammers | Atalanta | Eintracht Frankfurt | Loan |
| 31 August 2021 | Nicola Rauti | Torino | Pescara | Loan |
| 31 August 2021 | Jacopo Segre | Torino | Perugia | Loan |
| 31 August 2021 | David Zima | Slavia Prague | Torino | Undisclosed |
| 31 August 2021 | Dennis Praet | Leicester | Torino | Loan |
| 31 August 2021 | Josip Brekalo | VfL Wolfsburg | Torino | Loan |
| 31 August 2021 | Raoul Bellanova | Bordeaux | Cagliari | Loan |
| 31 August 2021 | Keita Baldé | Monaco | Cagliari | Undisclosed |
| 31 August 2021 | Simone Pinna | Cagliari | Olbia | Undisclosed |
| 31 August 2021 | Enrico Brignola | Sassuolo | Benevento | Loan |
| 31 August 2021 | Nicholas Pierini | Sassuolo | Cesena | Undisclosed |
| 31 August 2021 | Martin Erlić | Spezia | Sassuolo | Undisclosed |
| 31 August 2021 | Martin Erlić | Sassuolo | Spezia | Loan |
| 31 August 2021 | Marco Pinato | Sassuolo | Pordenone | Loan |
| 31 August 2021 | Andrea Ghion | Sassuolo | Perugia | Loan |
| 31 August 2021 | Andrea Meroni | Sassuolo | Cremonese | Loan |
| 31 August 2021 | Brian Oddei | Sassuolo | Crotone | Loan |
| 31 August 2021 | Nicolás Schiappacasse | Peñarol | Sassuolo | Loan return |
| 31 August 2021 | Andrei Mărginean | Sassuolo | Messina | Loan |
| 31 August 2021 | Abdou Harroui | Sparta Rotterdam | Sassuolo | Loan |
| 31 August 2021 | Djenairo Daniels | Utrecht | Sassuolo | Loan |
| 1 September 2021 | Martín Cáceres | Unattached | Cagliari | Free |
| 1 September 2021 | Tommaso Aglietti | Unattached | Reggina | Free |
| 2 September 2021 | Pablo Galdames | Unattached | Genoa | Free |
| 2 September 2021 | Samuel Mráz | Spezia | Slovan Bratislava | Loan |
| 4 September 2021 | Matthieu Huard | Unattached | Brescia | Free |
| 6 September 2021 | Franck Ribéry | Unattached | Salernitana | Free |
| 8 September 2021 | Stefano Okaka | Udinese | Başakşehir | Undisclosed |
| 17 September 2021 | Cedric Gondo | Lazio | Salernitana | Free |
| 28 September 2021 | Aurélien Nguiamba | Unattached | Spezia | Free |

## Footnotes

* 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 The player already played for his new club in 2020-21 season, the deal turned from temporary to definitive.