# List of Major League Soccer transfers 2022

The following is a list of transfers for the 2022 Major League Soccer (MLS) season that have been made during the 2021–22 MLS offseason all the way through to the roster freeze.

## Transfers

List of 2022 MLS transfers :
| Date | Name | Moving from | Moving to | Mode of Transfer |
| October 12, 2021 | Missael Rodríguez | Chicago Fire Academy | Chicago Fire FC | Homegrown player |
| October 23, 2021 | Sergio Oregel | Chicago Fire Academy | Chicago Fire FC | Homegrown player |
| December 5, 2021 | Gabriele Corbo | Bologna | CF Montréal | Loan |
| December 12, 2021 | Teal Bunbury | New England Revolution | Nashville SC | Trade |
| December 12, 2021 | Franco Escobar | Atlanta United FC | Los Angeles FC | Trade |
| December 12, 2021 | Jaylin Lindsey | Sporting Kansas City | Charlotte FC | Trade |
| December 12, 2021 | Lewis Morgan | Inter Miami CF | New York Red Bulls | Trade |
| December 12, 2021 | Jean Mota | Santos | Inter Miami CF | Transfer |
| December 12, 2021 | Pablo Sisniega | Los Angeles FC | Charlotte FC | Trade |
| December 12, 2021 | Daniel Steres | LA Galaxy | Houston Dynamo FC | Trade |
| December 12, 2021 | Ethan Zubak | LA Galaxy | Nashville SC | Trade |
| December 13, 2021 | Eduard Atuesta | Los Angeles FC | Palmeiras | Transfer |
| December 13, 2021 | Vinicius Mello | Internacional | Charlotte FC | Transfer |
| December 14, 2021 | Samuel Adeniran | Tacoma Defiance | Seattle Sounders FC | Free |
| December 14, 2021 | Tristan Blackmon | Los Angeles FC | Charlotte FC | Expansion Draft |
| December 14, 2021 | Tristan Blackmon | Charlotte FC | Vancouver Whitecaps FC | Trade |
| December 14, 2021 | McKinze Gaines | Austin FC | Charlotte FC | Expansion Draft |
| December 14, 2021 | Joseph Mora | D.C. United | Charlotte FC | Expansion Draft |
| December 14, 2021 | Ismael Tajouri-Shradi | New York City FC | Charlotte FC | Expansion Draft |
| December 14, 2021 | Ismael Tajouri-Shradi | Charlotte FC | Los Angeles FC | Trade |
| December 14, 2021 | Obed Vargas | Tacoma Defiance | Seattle Sounders FC | Homegrown player |
| December 14, 2021 | Anton Walkes | Atlanta United FC | Charlotte FC | Expansion Draft |
| December 16, 2021 | Alec Kann | Atlanta United FC | FC Cincinnati | Free |
| December 16, 2021 | Ariel Lassiter | Houston Dynamo FC | Inter Miami CF | Trade |
| December 16, 2021 | Sebastian Lletget | LA Galaxy | New England Revolution | Trade |
| December 16, 2021 | Dylan Nealis | Nashville SC | New York Red Bulls | Trade |
| December 17, 2021 | Mo Adams | Atlanta United FC | Inter Miami CF | Trade |
| December 17, 2021 | Harrison Afful | Columbus Crew | Charlotte FC | Free |
| December 17, 2021 | Josh Bauer | Atlanta United FC | Nashville SC | Re-Entry Draft Stage 1 |
| December 17, 2021 | Dylan Castanheira | Inter Miami CF | Atlanta United FC | Trade |
| December 17, 2021 | Daniel Edelman | New York Red Bulls II | New York Red Bulls | Homegrown player |
| December 17, 2021 | Alvas Powell | Philadelphia Union | FC Cincinnati | Free |
| December 17, 2021 | Yordy Reyna | D.C. United | Charlotte FC | Free |
| December 18, 2021 | Justin Portillo | Real Salt Lake | New Mexico United | Free |
| December 20, 2021 | Ethan Finlay | Minnesota United FC | Austin FC | Free |
| December 20, 2021 | Spencer Richey | Seattle Sounders FC | Chicago Fire FC | Free |
| December 20, 2021 | Ben Sweat | Austin FC | Sporting Kansas City | Free |
| December 21, 2021 | Alan Franco | Atlético Mineiro | Charlotte FC | Loan |
| December 21, 2021 | Oriol Rosell | Orlando City SC | Sporting Kansas City | Free |
| December 22, 2021 | Victor Bezerra | Indiana Hoosiers | Chicago Fire FC | Homegrown player |
| December 22, 2021 | Steve Clark | Portland Timbers | Houston Dynamo FC | Free |
| December 22, 2021 | Omar Gonzalez | Toronto FC | New England Revolution | Free |
| December 22, 2021 | Shane O'Neill | Seattle Sounders FC | Toronto FC | Free |
| December 23, 2021 | Bryan Acosta | FC Dallas | Colorado Rapids | Re-Entry Draft Stage 2 |
| December 23, 2021 | Osvaldo Alonso | Minnesota United FC | Atlanta United FC | Free |
| December 23, 2021 | Robert Berić | Chicago Fire FC | Sporting Kansas City | Re-Entry Draft Stage 2 |
| December 23, 2021 | Julián Carranza | Inter Miami CF | Philadelphia Union | Loan |
| December 23, 2021 | Eric Dick | Columbus Crew | Minnesota United FC | Re-Entry Draft Stage 2 |
| December 23, 2021 | Jonathan dos Santos | LA Galaxy | Club América | Free |
| December 23, 2021 | Ján Greguš | Minnesota United FC | San Jose Earthquakes | Re-Entry Draft Stage 2 |
| December 23, 2021 | John Nelson | FC Dallas | FC Cincinnati | Re-Entry Draft Stage 2 |
| December 23, 2021 | Brady Scott | Austin FC | Columbus Crew | Re-Entry Draft Stage 2 |
| December 27, 2021 | Alistair Johnston | Nashville SC | CF Montréal | Trade |
| December 28, 2021 | Kristijan Kahlina | Ludogorets Razgrad | Charlotte FC | Transfer |
| December 28, 2021 | Kyle Morton | Houston Dynamo FC | Louisville City | Free |
| December 28, 2021 | Maximiliano Urruti | Houston Dynamo FC | Austin FC | Free |
| January 1, 2022 | Jordy Alcívar | L.D.U. Quito | Charlotte FC | Transfer |
| January 1, 2022 | Ignacio Aliseda | Chicago Fire FC | FC Lugano | Transfer |
| January 1, 2022 | Ventura Alvarado | Inter Miami CF | FC Juárez | Free |
| January 1, 2022 | Carlos Miguel Coronel | Red Bull Salzburg | New York Red Bulls | Transfer |
| January 1, 2022 | Guzmán Corujo | Nacional | Charlotte FC | Free |
| January 1, 2022 | Daryl Dike | Orlando City SC | West Bromwich Albion | Transfer |
| January 1, 2022 | Kyle Duncan | New York Red Bulls | Oostende | Free |
| January 1, 2022 | Julian Dunn | Toronto FC | HamKam | Free |
| January 1, 2022 | Jhon Durán | Envigado | Chicago Fire FC | Transfer |
| January 1, 2022 | Ahmed Hamdy | El Gouna | CF Montréal | Transfer |
| January 1, 2022 | Žan Kolmanič | Maribor | Austin FC | Transfer |
| January 1, 2022 | Lassi Lappalainen | Bologna | CF Montréal | Transfer |
| January 1, 2022 | Álvaro Medrán | Chicago Fire FC | Al-Taawoun | Free |
| January 1, 2022 | Chris Mueller | Orlando City SC | Hibernian | Free |
| January 1, 2022 | Jukka Raitala | Minnesota United FC | HJK | Free |
| January 1, 2022 | Gaoussou Samaké | ASEC Mimosas | D.C. United | Transfer |
| January 1, 2022 | Joaquín Torres | Newell's Old Boys | CF Montréal | Transfer |
| January 1, 2022 | Gustavo Vallecilla | Aucas | FC Cincinnati | Transfer |
| January 2, 2022 | Rafael Czichos | FC Köln | Chicago Fire FC | Transfer |
| January 3, 2022 | Ricardo Pepi | FC Dallas | FC Augsburg | Transfer |
| January 4, 2022 | Dominique Badji | Colorado Rapids | FC Cincinnati | Free |
| January 4, 2022 | Sean Davis | New York Red Bulls | Nashville SC | Free |
| January 4, 2022 | Bryce Duke | Los Angeles FC | Inter Miami CF | Trade |
| January 4, 2022 | Brendan Hines-Ike | K.V. Kortrijk | D.C. United | Transfer |
| January 4, 2022 | Rodolfo Pizarro | Inter Miami CF | Monterrey | Loan |
| January 4, 2022 | Aedan Stanley | Austin FC | Miami FC | Free |
| January 5, 2022 | Alejandro Fuenmayor | Houston Dynamo FC | Oakland Roots | Free |
| January 5, 2022 | Ray Gaddis | Retired | FC Cincinnati | Free |
| January 5, 2022 | Bongokuhle Hlongwane | Maritzburg United | Minnesota United FC | Transfer |
| January 5, 2022 | Aboubacar Keita | Columbus Crew | Colorado Rapids | Trade |
| January 5, 2022 | James Sands | New York City FC | Rangers | Loan |
| January 5, 2022 | Caleb Stanko | FC Cincinnati | PAS Giannina | Free |
| January 6, 2022 | Max Alves | Flamengo | Colorado Rapids | Transfer |
| January 6, 2022 | Chris Hegardt | Georgetown Hoyas | Charlotte FC | Homegrown player |
| January 6, 2022 | Kelvin Leerdam | Inter Miami CF | LA Galaxy | Free |
| January 6, 2022 | Emmanuel Mas | Orlando City SC | Estudiantes | Free |
| January 6, 2022 | Yaw Yeboah | Wisła Kraków | Columbus Crew | Transfer |
| January 7, 2022 | Danilo Acosta | LA Galaxy | Orange County SC | Free |
| January 7, 2022 | César Araújo | Montevideo Wanderers | Orlando City SC | Transfer |
| January 7, 2022 | Elliot Collier | Chicago Fire FC | San Antonio FC | Free |
| January 7, 2022 | Raheem Edwards | Los Angeles FC | LA Galaxy | Free |
| January 8, 2022 | Richie Laryea | Toronto FC | Nottingham Forest | Transfer |
| January 8, 2022 | Erik Sorga | D.C. United | IFK Göteborg | Transfer |
| January 9, 2022 | Sebastian Breza | Bologna | CF Montréal | Loan |
| January 10, 2022 | José Bizama | Houston Dynamo FC | Palestino | Free |
| January 10, 2022 | Dom Dwyer | Toronto FC | FC Dallas | Trade |
| January 10, 2022 | Justin Garces | UCLA Bruins | Atlanta United FC | Homegrown player |
| January 10, 2022 | Leandro González Pírez | Inter Miami CF | River Plate | Loan |
| January 10, 2022 | Christian Makoun | Inter Miami CF | Charlotte FC | Trade |
| January 10, 2022 | Nanu | Porto | FC Dallas | Loan |
| January 10, 2022 | Tomás Pochettino | Austin FC | River Plate | Loan |
| January 11, 2022 | Ben Bender | Maryland Terrapins | Charlotte FC | SuperDraft |
| January 11, 2022 | Ousseni Bouda | Stanford Cardinal | San Jose Earthquakes | SuperDraft |
| January 11, 2022 | Roman Celentano | Indiana Hoosiers | FC Cincinnati | SuperDraft |
| January 11, 2022 | Erik Centeno | Pacific Tigers | Atlanta United FC | SuperDraft |
| January 11, 2022 | Clément Diop | CF Montréal | Inter Miami CF | Free |
| January 11, 2022 | Tega Ikoba | North Carolina Tar Heels | Portland Timbers | Homegrown player |
| January 11, 2022 | Kipp Keller | Saint Louis Billikens | Austin FC | SuperDraft |
| January 11, 2022 | David Loera | Orlando City SC | San Antonio FC | Free |
| January 11, 2022 | Isaiah Parker | Saint Louis Billikens | FC Dallas | SuperDraft |
| January 11, 2022 | Luca Petrasso | Toronto FC II | Toronto FC | Homegrown player |
| January 11, 2022 | Will Richmond | Stanford Cardinal | San Jose Earthquakes | Homegrown player |
| January 11, 2022 | Patrick Schulte | Saint Louis Billikens | Columbus Crew | SuperDraft |
| January 11, 2022 | Dylan Teves | Washington Huskies | Seattle Sounders FC | Homegrown player |
| January 11, 2022 | Thorleifur Úlfarsson | Duke Blue Devils | Houston Dynamo FC | SuperDraft |
| January 11, 2022 | Jude Wellings | Real Salt Lake Academy | Real Salt Lake | Homegrown player |
| January 12, 2022 | Julio Benitez | Real Monarchs | Real Salt Lake | Homegrown player |
| January 12, 2022 | Scott Caldwell | New England Revolution | Real Salt Lake | Free |
| January 12, 2022 | Jay Chapman | Inter Miami CF | Dundee | Free |
| January 12, 2022 | Ilie Sánchez | Sporting Kansas City | Los Angeles FC | Free |
| January 13, 2022 | Raul Aguilera | Orlando City SC | Indy Eleven | Free |
| January 13, 2022 | Gavin Beavers | Real Monarchs | Real Salt Lake | Homegrown player |
| January 13, 2022 | David Bingham | Unattached | Portland Timbers | Free |
| January 13, 2022 | Abu Danladi | Nashville SC | Minnesota United FC | Free |
| January 13, 2022 | Ted Ku-DiPietro | Loudoun United | D.C. United | Homegrown player |
| January 13, 2022 | Matt LaGrassa | Nashville SC | Sacramento Republic | Free |
| January 13, 2022 | Aimé Mabika | Fort Lauderdale CF | Inter Miami CF | Free |
| January 13, 2022 | Jaziel Orozco | Real Monarchs | Real Salt Lake | Homegrown player |
| January 13, 2022 | Albert Rusnák | Real Salt Lake | Seattle Sounders FC | Free |
| January 13, 2022 | Erick Torres | Atlanta United FC | Orange County SC | Free |
| January 13, 2022 | Jhojan Valencia | Deportivo Cali | Austin FC | Transfer |
| January 13, 2022 | Florian Valot | FC Cincinnati | Miami FC | Free |
| January 13, 2022 | Sean Zawadzki | Georgetown Hoyas | Columbus Crew | Homegrown player |
| January 14, 2022 | Kellyn Acosta | Colorado Rapids | Los Angeles FC | Trade |
| January 14, 2022 | Jalil Anibaba | Nashville SC | Columbus Crew | Free |
| January 14, 2022 | Amadou Dia | Sporting Kansas City | Louisville City | Free |
| January 14, 2022 | Kortne Ford | Colorado Rapids | Sporting Kansas City | Free |
| January 14, 2022 | Axel Kei | Real Monarchs | Real Salt Lake | Homegrown player |
| January 14, 2022 | Riley McGree | Charlotte FC | Middlesbrough | Transfer |
| January 14, 2022 | Christopher McVey | Elfsborg | Inter Miami CF | Transfer |
| January 14, 2022 | Jake Morris | Campbell Fighting Camels | Columbus Crew | Homegrown player |
| January 14, 2022 | Nani | Orlando City SC | Venezia | Free |
| January 14, 2022 | Logan Ndenbe | Guingamp | Sporting Kansas City | Transfer |
| January 14, 2022 | Noah Powder | Real Salt Lake | Indy Eleven | Free |
| January 14, 2022 | Bobby Shuttleworth | Chicago Fire FC | Atlanta United FC | Free |
| January 14, 2022 | Niko Tsakiris | Quakes Academy | San Jose Earthquakes | Homegrown player |
| January 15, 2022 | Rodrigo Piñeiro | Nashville SC | Unión Española | Loan |
| January 15, 2022 | Vito Wormgoor | Columbus Crew | Start | Free |
| January 16, 2022 | Damion Lowe | Al Ittihad | Inter Miami CF | Free |
| January 16, 2022 | Adrian Zendejas | Minnesota United FC | Charlotte FC | Free |
| January 17, 2022 | Ronald Hernández | Aberdeen | Atlanta United FC | Transfer |
| January 17, 2022 | Jesús Medina | New York City FC | CSKA Moscow | Free |
| January 18, 2022 | Noel Buck | New England Revolution II | New England Revolution | Homegrown player |
| January 18, 2022 | Toni Datković | Real Salt Lake | Cartagena | Transfer |
| January 18, 2022 | Sebastián Ferreira | Club Libertad | Houston Dynamo | Transfer |
| January 18, 2022 | Liam Fraser | Toronto FC | KMSK Deinze | Free |
| January 18, 2022 | Richard Sánchez | North Texas SC | LA Galaxy | Free |
| January 18, 2022 | Caleb Wiley | Atlanta United 2 | Atlanta United FC | Homegrown player |
| January 19, 2022 | Nicholas Benalcazar | Wake Forest Demon Deacons | New York City FC | Homegrown player |
| January 19, 2022 | Jonathan Jimenez | North Carolina Tar Heels | New York City FC | Homegrown player |
| January 19, 2022 | Cristian Ortíz | Tijuana | Charlotte FC | Loan |
| January 19, 2022 | Samuel Kwaku Owusu | NYCFC Academy | New York City FC | Homegrown player |
| January 19, 2022 | Emerson Rodriguez | Millonarios | Inter Miami CF | Transfer |
| January 19, 2022 | Robert Voloder | Maribor | Sporting Kansas City | Transfer |
| January 20, 2022 | Cole Bassett | Colorado Rapids | Feyenoord | Loan |
| January 20, 2022 | Leonardo Campana | Wolverhampton | Inter Miami CF | Loan |
| January 20, 2022 | Jesús Castellano | Yaracuyanos | New York Red Bulls | Transfer |
| January 20, 2022 | Maxime Crépeau | Vancouver Whitecaps FC | Los Angeles FC | Trade |
| January 20, 2022 | Jake LaCava | New York Red Bulls II | New York Red Bulls | Free |
| January 20, 2022 | Jake LaCava | New York Red Bulls | Tampa Bay Rowdies | Loan |
| January 20, 2022 | Maarten Paes | Utrecht | FC Dallas | Loan |
| January 20, 2022 | Zach Ryan | Stanford Cardinal | New York Red Bulls | Homegrown player |
| January 20, 2022 | Patrick Seagrist | Inter Miami CF | Memphis 901 | Free |
| January 20, 2022 | Diego Valeri | Portland Timbers | Lanús | Transfer |
| January 21, 2022 | Janio Bikel | Vancouver Whitecaps FC | L.R. Vicenza | Loan |
| January 21, 2022 | Justin Che | FC Dallas | TSG 1899 Hoffenheim | Loan |
| January 21, 2022 | Mark Delgado | Toronto FC | LA Galaxy | Trade |
| January 21, 2022 | Deandre Kerr | Syracuse Orange | Toronto FC | Homegrown player |
| January 21, 2022 | John McCarthy | Inter Miami CF | Los Angeles FC | Free |
| January 21, 2022 | Greg Ranjitsingh | MLS Pool | Toronto FC | Free |
| January 21, 2022 | Will Sands | Georgetown Hoyas | Columbus Crew | Homegrown player |
| January 22, 2022 | Kacper Przybyłko | Philadelphia Union | Chicago Fire FC | Trade |
| January 24, 2022 | Miloš Degenek | Red Star Belgrade | Columbus Crew | Free |
| January 24, 2022 | Nicolás Figal | Inter Miami CF | Boca Juniors | Transfer |
| January 24, 2022 | Ruben Gabrielsen | Toulouse | Austin FC | Transfer |
| January 24, 2022 | Ben Lundt | FC Cincinnati | Phoenix Rising | Free |
| January 24, 2022 | Hayden Sargis | Sacramento Republic | D.C. United | Free |
| January 24, 2022 | Facundo Torres | Peñarol | Orlando City SC | Transfer |
| January 24, 2022 | Marinos Tzionis | Omonia | Sporting Kansas City | Transfer |
| January 25, 2022 | Damian Las | Fulham | Austin FC | Transfer |
| January 25, 2022 | Lukas MacNaughton | Pacific FC | Toronto FC | Free |
| January 25, 2022 | Evan Newton | Vancouver Whitecaps FC | El Paso Locomotive | Loan |
| January 25, 2022 | Anthony Sorenson | Philadelphia Union II | Philadelphia Union | Homegrown player |
| January 25, 2022 | Luka Stojanović | Chicago Fire FC | Al-Hazem | Free |
| January 26, 2022 | Alexander Alvarado | Orlando City SC | L.D.U. Quito | Loan |
| January 26, 2022 | Paul Arriola | D.C. United | FC Dallas | Trade |
| January 26, 2022 | Francisco Calvo | Chicago Fire FC | San Jose Earthquakes | Free |
| January 26, 2022 | James Igbekeme | Real Zaragoza | Columbus Crew | Loan |
| January 26, 2022 | Mathias Jørgensen | New York Red Bulls | Esbjerg | Free |
| January 26, 2022 | Karol Świderski | PAOK | Charlotte FC | Transfer |
| January 26, 2022 | Justin Vom Steeg | LA Galaxy | Portland Timbers | Free |
| January 27, 2022 | Ercan Kara | Rapid Vienna | Orlando City SC | Transfer |
| January 27, 2022 | Douglas Martínez | Real Salt Lake | Sacramento Republic | Free |
| January 27, 2022 | Brad Smith | Seattle Sounders FC | D.C. United | Trade |
| January 27, 2022 | Mikael Uhre | Brøndby | Philadelphia Union | Transfer |
| January 28, 2022 | Mateo Bajamich | Houston Dynamo | CA Huracán | Loan |
| January 28, 2022 | Lucas Bartlett | St. John's Red Storm | FC Dallas | SuperDraft |
| January 28, 2022 | Sami Guediri | Inter Miami CF | Loudoun United | Free |
| January 28, 2022 | Grant Lillard | Columbus Crew | Loudoun United | Free |
| January 28, 2022 | Trey Muse | Seattle Sounders FC | Loudoun United | Free |
| January 28, 2022 | Kevin Paredes | D.C. United | VfL Wolfsburg | Transfer |
| January 29, 2022 | Esequiel Barco | Atlanta United FC | River Plate | Loan |
| January 30, 2022 | Milton Valenzuela | Columbus Crew | Lugano | Free |
| January 31, 2022 | Theo Bair | Vancouver Whitecaps FC | St Johnstone | Transfer |
| January 31, 2022 | George Bello | Atlanta United FC | Arminia Bielefeld | Transfer |
| January 31, 2022 | Jamal Blackman | Los Angeles FC | Huddersfield Town | Free |
| January 31, 2022 | Carlos Salcedo | Tigres | Toronto FC | Transfer |
| January 31, 2022 | Yeferson Soteldo | Toronto FC | Tigres | Transfer |
| January 31, 2022 | Auston Trusty | Colorado Rapids | Arsenal | Transfer |
| January 31, 2022 | Auston Trusty | Arsenal | Colorado Rapids | Loan |
| February 1, 2022 | David Ayala | Estudiantes | Portland Timbers | Transfer |
| February 1, 2022 | Tsubasa Endoh | Toronto FC | Melbourne City | Free |
| February 1, 2022 | Ashtone Morgan | Real Salt Lake | Forge FC | Free |
| February 1, 2022 | Selmir Pidro | Sarajevo | St. Louis City SC | Transfer |
| February 1, 2022 | Alan Velasco | Independiente | FC Dallas | Transfer |
| February 2, 2022 | Yamil Asad | D.C. United | Universidad Católica | Free |
| February 2, 2022 | Oniel Fisher | LA Galaxy | Minnesota United FC | Free |
| February 2, 2022 | Marko Marić | Houston Dynamo | Atromitos | Free |
| February 2, 2022 | DeAndre Yedlin | Galatasaray | Inter Miami CF | Free |
| February 3, 2022 | Sergio Córdova | FC Augsburg | Real Salt Lake | Loan |
| February 3, 2022 | Wilson Harris | Sporting Kansas City | Louisville City | Free |
| February 4, 2022 | Sebastian Berhalter | Columbus Crew | Vancouver Whitecaps FC | Trade |
| February 4, 2022 | Brooklyn Raines | El Paso Locomotive | Houston Dynamo FC | Homegrown player |
| February 5, 2022 | Ethan Dobbelaere | Seattle Sounders FC | MFK Vyškov | Loan |
| February 7, 2022 | Felipe | D.C. United | Austin FC | Free |
| February 7, 2022 | Jesús Jiménez | Górnik Zabrze | Toronto FC | Transfer |
| February 7, 2022 | Kekuta Manneh | Austin FC | San Antonio FC | Free |
| February 7, 2022 | Thiago Martins | Yokohama F. Marinos | New York City FC | Transfer |
| February 8, 2022 | Michael Estrada | Toluca | D.C. United | Loan |
| February 8, 2022 | Josecarlos Van Rankin | Chivas | Portland Timbers | Loan |
| February 9, 2022 | Thiago Almada | Vélez Sarsfield | Atlanta United FC | Transfer |
| February 9, 2022 | Caden Clark | RB Leipzig | New York Red Bulls | Loan |
| February 9, 2022 | Xherdan Shaqiri | Lyon | Chicago Fire FC | Transfer |
| February 10, 2022 | Douglas Costa | Juventus | LA Galaxy | Loan |
| February 10, 2022 | Marco Farfan | Los Angeles FC | FC Dallas | Trade |
| February 10, 2022 | Ryan Hollingshead | FC Dallas | Los Angeles FC | Trade |
| February 10, 2022 | Zeca | Vasco da Gama | Houston Dynamo | Free |
| February 11, 2022 | CJ dos Santos | Benfica B | Inter Miami CF | Transfer |
| February 11, 2022 | Tsiki Ntsabeleng | Oregon State Beavers | FC Dallas | SuperDraft |
| February 11, 2022 | Robert Taylor | Brann | Inter Miami CF | Transfer |
| February 14, 2022 | Jozy Altidore | Toronto FC | New England Revolution | Free |
| February 14, 2022 | Auro Jr. | Toronto FC | Santos | Loan |
| February 14, 2022 | Jamiro Monteiro | Philadelphia Union | San Jose Earthquakes | Trade |
| February 14, 2022 | Roberto Punčec | Sporting Kansas City | Botev Plovdiv | Free |
| February 14, 2022 | Jackson Ragen | Tacoma Defiance | Seattle Sounders FC | Free |
| February 15, 2022 | Alex Freeman | Orlando City U17 | Orlando City SC | Homegrown player |
| February 15, 2022 | Jacob Jackson | Loyola Marymount Lions | New England Revolution | SuperDraft |
| February 15, 2022 | Nikola Vujnović | Voždovac | Sporting Kansas City | Loan |
| February 16, 2022 | Kervin Arriaga | Marathón | Minnesota United FC | Transfer |
| February 16, 2022 | Luquinhas | Legia Warsaw | New York Red Bulls | Transfer |
| February 16, 2022 | Jack Lynn | Notre Dame Fighting Irish | Orlando City SC | SuperDraft |
| February 16, 2022 | Logan Ketterer | El Paso Locomotive | CF Montréal | Free |
| February 17, 2022 | Tom Edwards | Stoke City | New York Red Bulls | Loan |
| February 17, 2022 | Joe Gyau | FC Cincinnati | Degerfors IF | Free |
| February 17, 2022 | Serge Ngoma | New York Red Bulls II | New York Red Bulls | Free |
| February 17, 2022 | Justin Rasmussen | Grand Canyon Antelopes | Portland Timbers | SuperDraft |
| February 18, 2022 | Oskar Ågren | Clemson Tigers | San Jose Earthquakes | SuperDraft |
| February 18, 2022 | Doneil Henry | Suwon Bluewings | Los Angeles FC | Free |
| February 18, 2022 | Kei Kamara | HIFK | CF Montréal | Free |
| February 18, 2022 | Johan Kappelhof | Chicago Fire FC | Real Salt Lake | Free |
| February 18, 2022 | Tony Rocha | New York City FC | Orange County SC | Free |
| February 18, 2022 | Ryan Spaulding | New England Revolution II | New England Revolution | Free |
| February 19, 2022 | Luis Amarilla | Vélez Sarsfield | Minnesota United FC | Transfer |
| February 19, 2022 | Jairo Torres | Atlas | Chicago Fire FC | Transfer |
| February 21, 2022 | Antonio Carrera | North Texas SC | FC Dallas | Free |
| February 22, 2022 | Dom Dwyer | FC Dallas | Atlanta United FC | Free |
| February 22, 2022 | Erik López | Atlanta United FC | Banfield | Loan |
| February 22, 2022 | Koa Santos | San Diego State Aztecs | Charlotte FC | Free |
| February 23, 2022 | Charlie Asensio | Clemson Tigers | Austin FC | SuperDraft |
| February 23, 2022 | Kadin Chung | Pacific FC | Toronto FC | Free |
| February 23, 2022 | Nick Markanich | Northern Illinois Huskies | FC Cincinnati | SuperDraft |
| February 23, 2022 | Ian Murphy | Duke Blue Devils | FC Cincinnati | SuperDraft |
| February 25, 2022 | Kendall Burks | Washington Huskies | Chicago Fire FC | SuperDraft |
| February 25, 2022 | Sofiane Djeffal | Oregon State Beavers | D.C. United | SuperDraft |
| February 25, 2022 | Diego Gutierrez | Creighton Bluejays | Portland Timbers | SuperDraft |
| February 25, 2022 | Júnior Moreno | D.C. United | FC Cincinnati | Trade |
| February 25, 2022 | Tani Oluwaseyi | St. John's Red Storm | Minnesota United FC | SuperDraft |
| February 25, 2022 | Daniel Ríos | Nashville SC | Charlotte FC | Trade |
| February 25, 2022 | Harrison Robledo | FC Cincinnati Academy | FC Cincinnati | Homegrown player |
| February 25, 2022 | Kosi Thompson | Toronto FC II | Toronto FC | Homegrown player |
| February 25, 2022 | Jürgen Damm | Atlanta United FC | Unattached | Buyout |
| February 27, 2022 | Jasper Löeffelsend | Pittsburgh Panthers | Real Salt Lake | SuperDraft |
| February 27, 2022 | Xavier Valdez | Houston Dynamo Academy | Houston Dynamo FC | Homegrown player |
| February 28, 2022 | Maximo Carrizo | New York City FC Academy | New York City FC | Homegrown player |
| February 28, 2022 | Ashley Fletcher | Watford | New York Red Bulls | Loan |
| March 1, 2022 | Matt Hundley | Colorado Rapids | Unattached | Free |
| March 3, 2022 | Anthony Markanich | Northern Illinois Huskies | Colorado Rapids | SuperDraft |
| March 3, 2022 | Joshué Quiñónez | Barcelona SC | FC Dallas | Loan |
| March 3, 2022 | Luke Singh | Toronto FC | FC Edmonton | Loan |
| March 4, 2022 | Jackson Travis | Colorado Rapids Academy | Colorado Rapids | Homegrown Player |
| March 7, 2022 | Kevin O'Toole | Princeton Tigers | New York City FC | SuperDraft |
| March 9, 2022 | Derrick Jones | Houston Dynamo | Charlotte FC | Trade |
| March 10, 2022 | Kamil Jóźwiak | Derby County | Charlotte FC | Transfer |
| March 10, 2022 | Devin Padelford | Minnesota United Academy | Minnesota United FC | Homegrown player |
| March 10, 2022 | Eriq Zavaleta | Toronto FC | LA Galaxy | Free |
| March 11, 2022 | Noah Allen | Inter Miami II | Inter Miami CF | Homegrown player |
| March 11, 2022 | Kamron Habibullah | Vancouver Whitecaps FC | Pacific FC | Loan |
| March 12, 2022 | Freddy Kleemann | Austin FC | Birmingham Legion FC | Loan |
| March 12, 2022 | Will Pulisic | Austin FC | North Carolina FC | Loan |
| March 12, 2022 | Jonathan Sirois | CF Montréal | Valour FC | Loan |
| March 15, 2022 | Cody Cropper | FC Cincinnati | Vancouver Whitecaps FC | Free |
| March 17, 2022 | Kemar Lawrence | Toronto FC | Minnesota United FC | Trade |
| March 17, 2022 | Gabriel Pereira | Corinthians | New York City FC | Transfer |
| March 18, 2022 | Kim Moon-hwan | Los Angeles FC | Jeonbuk Hyundai Motors | Transfer |
| March 21, 2022 | Ronaldo Cisneros | Chivas Guadalajara | Atlanta United FC | Loan |
| March 21, 2022 | Taxiarchis Fountas | Rapid Vienna | D.C. United | Transfer |
| March 21, 2022 | Thiago | Flamengo | Houston Dynamo FC | Loan |
| March 24, 2022 | Chris Durkin | Sint-Truiden | D.C. United | Transfer |
| March 24, 2022 | Omar Sowe | New York Red Bulls | Breiðablik | Loan |
| March 28, 2022 | Gustavo Vallecilla | FC Cincinnati | Colorado Rapids | Transfer |
| March 29, 2022 | Joe Corona | Houston Dynamo FC | GIF Sundsvall | Loan |
| April 4, 2022 | Preston Judd | LA Galaxy II | LA Galaxy | Free |
| April 5, 2022 | Quinn McNeill | Clemson Tigers | Charlotte FC | Transfer |
| April 5, 2022 | Quinn McNeill | Charlotte FC | Charlotte Independence | Loan |
| April 6, 2022 | Djordje Petrović | Čukarički | New England Revolution | Transfer |
| April 8, 2022 | Jojea Kwizera | Utah Valley Wolverines | CF Montréal | SuperDraft |
| April 13, 2022 | Obinna Nwobodo | Göztepe S.K. | FC Cincinnati | Transfer |
| April 13, 2022 | Jackson Hopkins | Loudoun United | D.C. United | Homegrown Player |
| April 22, 2022 | Gyasi Zardes | Columbus Crew | Colorado Rapids | Trade |
| April 25, 2022 | Nathan Ordaz | LAFC Academy | Los Angeles FC | Homegrown player |
| April 27, 2022 | Rocco Ríos Novo | Lanús | Atlanta United FC | Loan |
| April 27, 2022 | Rafael Romo | OH Leuven | D.C. United | Transfer |
| April 28, 2022 | Andrés Cubas | Nîmes | Vancouver Whitecaps FC | Free |
| April 28, 2022 | Anderson Julio | Atlético San Luis | Real Salt Lake | Transfer |
| May 2, 2022 | Kerwin Vargas | CD Feirense | Charlotte FC | Transfer |
| May 3, 2022 | Andre Shinyashiki | Colorado Rapids | Charlotte FC | Trade |
| May 4, 2022 | Chase Gasper | Minnesota United FC | LA Galaxy | Trade |
| May 4, 2022 | Chris Kablan | SK Beveren | Real Salt Lake | Loan |
| May 4, 2022 | Luís Martins | Sporting Kansas City | Vancouver Whitecaps FC | Free |
| May 4, 2022 | Thomas Roberts | Austria Klagenfurt | FC Dallas | Loan Return |
| May 4, 2022 | Jefferson Savarino | Atlético Mineiro | Real Salt Lake | Transfer |
| May 5, 2022 | Nathan Fogaça | Coritiba | Portland Timbers | Transfer |
| May 5, 2022 | Gastón González | Unión Santa Fe | Orlando City SC | Transfer |
| May 5, 2022 | Jake Mulraney | Atlanta United FC | Orlando City SC | Trade |
| May 5, 2022 | Chris Mueller | Hibernian F.C. | Chicago Fire FC | Free |
| May 5, 2022 | Indiana Vassilev | Aston Villa | Inter Miami CF | Loan |
| May 6, 2022 | Beto Avila | Houston Dynamo 2 | Hpuston Dynamo | Free |
| May 10, 2022 | Adalberto Carrasquilla | FC Cartagena | Houston Dynamo FC | Transfer |
| May 12, 2022 | Justin Reynolds | Chicago Fire Academy | Chicago Fire FC | Homegrown Player |
| May 23, 2022 | Esmir Bajraktarevic | New England Revolution II | New England Revolution | Homegrown player |
| June 1, 2022 | Ben Reveno | New England Revolution II | New England Revolution | Free |
| June 3, 2022 | Diego Luna | El Paso Locomotive | Real Salt Lake | Transfer |
| June 3, 2022 | Cruz Medina | San Jose Earthquakes Academy | San Jose Earthquakes | Homegrown player |
| June 18, 2022 | Chris Donovan | Philadelphia Union II | Philadelphia Union | Free |
| June 23, 2022 | Edison Flores | D.C. United | Atlas | Transfer |
| June 27, 2022 | Alan Franco | Charlotte FC | Talleres | Loan |
| June 28, 2022 | Nicolás Mezquida | Colorado Rapids | Volos | Transfer |
| June 28, 2022 | Maarten Paes | FC Utrecht | FC Dallas | Transfer |
| June 29, 2022 | Jacen Russell-Rowe | Columbus Crew 2 | Columbus Crew | Homegrown player |
| July 1, 2022 | Douglas Costa | Juventus | LA Galaxy | Free |
| July 1, 2022 | Giorgio Chiellini | Juventus | Los Angeles FC | Free |
| July 1, 2022 | Hector Herrera | Atlético Madrid | Houston Dynamo FC | Free |
| July 1, 2022 | Adrien Hunou | Minnesota United FC | Angers | Transfer |
| July 1, 2022 | Lorenzo Insigne | Napoli | Toronto FC | Free |
| July 1, 2022 | Matt Turner | New England Revolution | Arsenal | Transfer |
| July 1, 2022 | Silvester van der Water | Orlando City SC | Cambuur | Transfer |
| July 4, 2022 | Griffin Yow | D.C. United | Westerlo | Transfer |
| July 7, 2022 | William Agada | Hapoel Jerusalem | Sporting Kansas City | Transfer |
| July 7, 2022 | Gareth Bale | Real Madrid | Los Angeles FC | Free |
| July 7, 2022 | Gastón Brugman | Parma | LA Galaxy | Transfer |
| July 7, 2022 | Francisco Calvo | San Jose Earthquakes | Konyaspor | Transfer |
| July 7, 2022 | Washington Corozo | Sporting Cristal | Austin FC | Loan |
| July 7, 2022 | Domenico Criscito | Genoa | Toronto FC | Free |
| July 7, 2022 | Jack de Vries | Philadelphia Union | Venezia | Transfer |
| July 7, 2022 | Raúl Gudiño | Guadalajara | Atlanta United FC | Free |
| July 7, 2022 | Cucho Hernández | Watford | Columbus Crew | Transfer |
| July 7, 2022 | Corentin Jean | Lens | Inter Miami CF | Transfer |
| July 7, 2022 | Sam Nicholson | Bristol Rovers | Colorado Rapids | Free |
| July 7, 2022 | Alejandro Pozuelo | Toronto FC | Inter Miami CF | Trade |
| July 7, 2022 | Juanjo Purata | Tigres UANL | Atlanta United FC | Loan |
| July 7, 2022 | Martín Rodríguez | Altay | D.C. United | Transfer |
| July 7, 2022 | Erik Thommy | VfB Stuttgart | Sporting Kansas City | Free |
| July 7, 2022 | Giacomo Vrioni | Juventus | New England Revolution | Transfer |
| July 7, 2022 | Tyler Wolff | Atlanta United FC | SK Beveren | Loan |
| July 8, 2022 | Matheus Aiás | Orlando City SC | Racing Santander | Transfer |
| July 8, 2022 | Mark-Anthony Kaye | Colorado Rapids | Toronto FC | Trade |
| July 8, 2022 | Aiden McFadden | Atlanta United 2 | Atlanta United FC | Free |
| July 8, 2022 | Ralph Priso | Toronto FC | Colorado Rapids | Trade |
| July 8, 2022 | Sérgio Santos | Philadelphia Union | FC Cincinnati | Trade |
| July 9, 2022 | Damiano Pecile | Vancouver Whitecaps FC | Venezia | Transfer |
| July 9, 2022 | Steven Sserwadda | New York Red Bulls II | New York Red Bulls | Free |
| July 10, 2022 | Adam Buksa | New England Revolution | Lens | Transfer |
| July 12, 2022 | Alan Benítez | Cerro Porteño | Minnesota United FC | Transfer |
| July 12, 2022 | Everton Luiz | Real Salt Lake | SK Beveren | Transfer |
| July 12, 2022 | Edwin Mosquera | Independiente Medellín | Atlanta United FC | Transfer |
| July 13, 2022 | Julián Carranza | Inter Miami CF | Philadelphia Union | Transfer |
| July 13, 2022 | Sami Guediri | Loudoun United | D.C. United | Free |
| July 13, 2022 | Jonathan Menéndez | Real Salt Lake | Vélez Sarsfield | Loan |
| July 13, 2022 | Jason Pendant | New York Red Bulls | Quevilly-Rouen | Transfer |
| July 15, 2022 | Federico Bernardeschi | Juventus | Toronto FC | Free |
| July 15, 2022 | Julian Gressel | D.C. United | Vancouver Whitecaps FC | Trade |
| July 15, 2022 | Carlos Salcedo | Toronto FC | Juárez | Free |
| July 19, 2022 | Francisco Ginella | Los Angeles FC | Nacional | Loan |
| July 19, 2022 | Sebas Méndez | Orlando City SC | Los Angeles FC | Trade |
| July 19, 2022 | Shaq Moore | CD Tenerife | Nashville SC | Transfer |
| July 20, 2022 | Miguel Berry | Columbus Crew | D.C. United | Trade |
| July 20, 2022 | Simon Colyn | Vancouver Whitecaps FC | Jong PSV | Transfer |
| July 20, 2022 | Nicholas Gioacchini | Caen | Orlando City SC | Transfer |
| July 20, 2022 | Stuart Findlay | Philadelphia Union | Oxford United | Transfer |
| July 21, 2022 | Ravel Morrison | Derby County | D.C. United | Transfer |
| July 23, 2022 | Mohamed Farsi | Columbus Crew 2 | Columbus Crew | Free |
| July 23, 2022 | Doneil Henry | Los Angeles FC | Toronto FC | Free |
| July 25, 2022 | Iván Angulo | Palmeiras | Orlando City SC | Loan |
| July 25, 2022 | Valentín Castellanos | New York City FC | Girona | Loan |
| July 25, 2022 | Alexandru Mitriță | New York City FC | Al Raed | Loan |
| July 27, 2022 | Juan David Mosquera | Independiente Medellín | Portland Timbers | Transfer |
| July 27, 2022 | Victor Pálsson | Schalke 04 | D.C. United | Transfer |
| July 27, 2022 | Nelson Quiñónes | Once Caldas | Houston Dynamo FC | Transfer |
| July 29, 2022 | Jozy Altidore | New England Revolution | Puebla | Loan |
| July 29, 2022 | David Ochoa | Real Salt Lake | D.C. United | Trade |
| July 29, 2022 | Emiliano Rigoni | São Paulo | Austin FC | Transfer |
| August 2, 2022 | Wilder Cartagena | Ittihad Kalba | Orlando City SC | Loan |
| August 2, 2022 | Richard Odada | Red Star Belgrade | Philadelphia Union | Transfer |
| August 2, 2022 | Jacob Shaffelburg | Toronto FC | Nashville SC | Loan |
| August 2, 2022 | Gabriel Slonina | Chicago Fire FC | Chelsea | Transfer |
| August 2, 2022 | Gabriel Slonina | Chelsea | Chicago Fire FC | Loan |
| August 3, 2022 | Felipe Gutiérrez | Universidad Católica | Colorado Rapids | Loan |
| August 3, 2022 | Sebastian Lletget | New England Revolution | FC Dallas | Trade |
| August 3, 2022 | Danny Musovski | Los Angeles FC | Real Salt Lake | Trade |
| August 3, 2022 | Brian Romero | Charlotte FC Academy | Charlotte FC | Homegrown player |
| August 3, 2022 | Alessandro Schöpf | Arminia Bielefeld | Vancouver Whitecaps FC | Free |
| August 4, 2022 | Abasa Aremeyaw | Žilina | Philadelphia Union | Transfer |
| August 4, 2022 | Nathan Byrne | Derby County | Charlotte FC | Transfer |
| August 4, 2022 | Christian Makoun | Charlotte FC | New England Revolution | Trade |
| August 4, 2022 | Braian Ojeda | Nottingham Forest | Real Salt Lake | Loan |
| August 4, 2022 | Riqui Puig | FC Barcelona | LA Galaxy | Free |
| August 4, 2022 | Rayan Raveloson | LA Galaxy | AJ Auxerre | Transfer |
| August 4, 2022 | Nuno Santos | Benfica | Charlotte FC | Transfer |
| August 5, 2022 | Carlos Akapo | Cádiz CF | San Jose Earthquakes | Transfer |
| August 5, 2022 | Christian Benteke | Crystal Palace | D.C. United | Transfer |
| August 5, 2022 | Denis Bouanga | Saint-Étienne | Los Angeles FC | Transfer |
| August 5, 2022 | Clément Diop | Inter Miami CF | New England Revolution | Trade |
| August 5, 2022 | Kyle Duncan | Oostende | New York Red Bulls | Loan |
| August 5, 2022 | Ménder García | Once Caldas | Minnesota United FC | Transfer |
| August 5, 2022 | Richie Laryea | Nottingham Forest | Toronto FC | Loan |
| August 5, 2022 | Chinonso Offor | Chicago Fire FC | CF Montréal | Trade |
| August 5, 2022 | Bryan Oviedo | FC Copenhagen | Real Salt Lake | Free |
| August 5, 2022 | Ismael Tajouri-Shradi | Los Angeles FC | New England Revolution | Trade |
| August 6, 2022 | Elias Manoel | Grêmio | New York Red Bulls | Loan |
| August 6, 2022 | Rodrigues | Grêmio | San Jose Earthquakes | Loan |
| August 7, 2022 | Isaac Atanga | FC Cincinnati | Göztepe | Loan |
| August 7, 2022 | Jonathan González | C.F. Monterrey | Minnesota United FC | Loan |
| August 8, 2022 | Marcos López | San Jose Earthquakes | Feyenoord | Transfer |
| August 9, 2022 | Alexandru Mățan | Columbus Crew | Rapid București | Loan |
| August 9, 2022 | Sergio Ruiz | Charlotte FC | Granada | Transfer |
| August 10, 2022 | Tyler Pasher | Houston Dynamo FC | New York Red Bulls | Waivers |
| August 10, 2022 | Arnór Ingvi Traustason | New England Revolution | IFK Norrköping | Free |
| August 16, 2022 | Caio Alexandre | Vancouver Whitecaps FC | Fortaleza | Loan |
| August 19, 2022 | Handwalla Bwana | Nashville SC | Memphis 901 | Loan |
| August 19, 2022 | Matías Pellegrini | Inter Miami CF | New York City FC | Waivers |
| August 22, 2022 | Evan Louro | Unattached | FC Cincinnati | Free |
| August 23, 2022 | Nacho Gil | FC Cartagena | New England Revolution | Free |
| August 23, 2022 | Harvey Neville | Inter Miami II | Inter Miami CF | Free |
| August 23, 2022 | Jeremy Rafanello | New York Red Bulls II | Philadelphia Union | Homegrown player |
| August 24, 2022 | Martín Cáceres | Levante | LA Galaxy | Free |
| August 24, 2022 | Brian Rodríguez | Los Angeles FC | Club América | Transfer |
| August 25, 2022 | Mamadou Fall | Los Angeles FC | Villarreal | Loan |
| August 26, 2022 | Matt Nocita | Navy Midshipmen | New York Red Bulls | SuperDraft |
| August 26, 2022 | Szabolcs Schön | FC Dallas | Fehérvár | Transfer |
| August 26, 2022 | Cristian Tello | Real Betis | Los Angeles FC | Free |
| August 29, 2022 | Moses Nyeman | D.C. United | S.K. Beveren | Transfer |
| August 30, 2022 | Bernard Kamungo | North Texas SC | FC Dallas | Free |
| August 31, 2022 | Matai Akinmboni | Loudoun United | D.C. United | Homegrown player |
| September 2, 2022 | Miguel Trauco | Saint-Étienne | San Jose Earthquakes | Free |
| September 3, 2022 | Hassan Ndam | New York Red Bulls II | New York Red Bulls | Free |