# List of United States senators from Massachusetts

Below is a chronological listing of the United States senators from Massachusetts. According to the Seventeenth Amendment to the United States Constitution adopted in 1913, U.S. senators are popularly elected for a six-year term. Elections are held the first Tuesday after November 1, and terms begin on January 3, about two months after the vote. Before 1914, and the enforcement of the Seventeenth Amendment, the state's U.S. senators were chosen by the Massachusetts General Court, and before 1935, their terms began March 4.
The current senators are Democrats Elizabeth Warren and Ed Markey. Ted Kennedy was Massachusetts's longest-serving senator, serving from 1962 until his death in 2009. Massachusetts is one of fifteen states alongside California, Colorado, Florida, Georgia, Hawaii, Idaho, Louisiana, Maine, Minnesota, Missouri, Nevada, Pennsylvania, South Dakota and Utah to have a younger senior senator and an older junior senator.

## Mid-term vacancy appointment processes

Through the 20th century, mid-term vacancies were filled with the governor's appointee, with the appointment expiring at the next biennial state election. In 2004, the Democratic-controlled state legislature changed the vacancy-filling process, mandating that a special election occur, which removed the governor's appointment power. This statute was enacted over the veto by the governor, Mitt Romney. The leadership of the Massachusetts legislature at the time was concerned that the Republican Governor Mitt Romney would appoint a Republican if Democratic Senator John Kerry were elected president of the United States in the 2004 election. Generally, the law requires a special election within 145 to 160 days from the date of the filing of a Senate resignation. The law contemplates resignations that become effective some period of time after the filing of the resignation, so long as the election occurs after effective date of the resignation.
While terminally ill with brain cancer, Ted Kennedy requested that the Massachusetts legislature change the law to allow an interim appointment. Kennedy died shortly thereafter, and the legislature quickly passed a bill providing for an interim appointment. On September 24, 2009, Governor Deval Patrick signed the bill, and appointed Paul G. Kirk, who had previously served as one of Kennedy's congressional aides and as chairman of the Democratic National Committee.

## List of senators

| Class 1Class 1 U.S. senators belong to the electoral cycle that has recently been contested in 2012, 2010 (special election), 2018, and 2024. The next election will be in 2030. | Class 1Class 1 U.S. senators belong to the electoral cycle that has recently been contested in 2012, 2010 (special election), 2018, and 2024. The next election will be in 2030. | Class 1Class 1 U.S. senators belong to the electoral cycle that has recently been contested in 2012, 2010 (special election), 2018, and 2024. The next election will be in 2030. | Class 1Class 1 U.S. senators belong to the electoral cycle that has recently been contested in 2012, 2010 (special election), 2018, and 2024. The next election will be in 2030. | Class 1Class 1 U.S. senators belong to the electoral cycle that has recently been contested in 2012, 2010 (special election), 2018, and 2024. The next election will be in 2030. | Class 1Class 1 U.S. senators belong to the electoral cycle that has recently been contested in 2012, 2010 (special election), 2018, and 2024. The next election will be in 2030. | C | Class 2Class 2 U.S. senators belong to the electoral cycle that has recently been contested in 2008, 2013 (special election), 2014, and 2020. The next election will be in 2026. | Class 2Class 2 U.S. senators belong to the electoral cycle that has recently been contested in 2008, 2013 (special election), 2014, and 2020. The next election will be in 2026. | Class 2Class 2 U.S. senators belong to the electoral cycle that has recently been contested in 2008, 2013 (special election), 2014, and 2020. The next election will be in 2026. | Class 2Class 2 U.S. senators belong to the electoral cycle that has recently been contested in 2008, 2013 (special election), 2014, and 2020. The next election will be in 2026. | Class 2Class 2 U.S. senators belong to the electoral cycle that has recently been contested in 2008, 2013 (special election), 2014, and 2020. The next election will be in 2026. | Class 2Class 2 U.S. senators belong to the electoral cycle that has recently been contested in 2008, 2013 (special election), 2014, and 2020. The next election will be in 2026. |
| # | Senator | Party | Dates in office | Electoral history | T | C | T | Electoral history | Dates in office | Party | Senator | # |
| 1 | Tristram Dalton | Pro- Admin. | Mar 4, 1789 – Mar 3, 1791 | Elected in 1788.Lost re-election. | 1 | 1st | 1 | Elected in 1788. | Mar 4, 1789 – Jun 1, 1796 | Pro- Admin. | Caleb Strong | 1 |
| 2 | George Cabot | Pro- Admin. | Mar 4, 1791 – Jun 9, 1796 | Elected in 1790.Resigned. | 2 | 2nd | 1 | Elected in 1788. | Mar 4, 1789 – Jun 1, 1796 | Pro- Admin. | Caleb Strong | 1 |
| 2 | George Cabot | Pro- Admin. | Mar 4, 1791 – Jun 9, 1796 | Elected in 1790.Resigned. | 2 | 3rd | 2 | Re-elected in 1793.Resigned. | Mar 4, 1789 – Jun 1, 1796 | Pro- Admin. | Caleb Strong | 1 |
| 2 | George Cabot | Federalist | Mar 4, 1791 – Jun 9, 1796 | Elected in 1790.Resigned. | 2 | 4th | 2 | Re-elected in 1793.Resigned. | Mar 4, 1789 – Jun 1, 1796 | Federalist | Caleb Strong | 1 |
| Vacant | Vacant | Vacant | Jun 9, 1796 – Jun 11, 1796 | Vacant | 2 | 4th | 2 | Vacant | Jun 1, 1796 – Jun 11, 1796 | Vacant | Vacant | Vacant |
| 3 | Benjamin Goodhue | Federalist | Jun 11, 1796 – Nov 8, 1800 | Elected to finish Cabot's term. | 2 | 4th | 2 | Elected to finish Strong's term.Retired to run for the U.S. House of Representatives. | Jun 11, 1796 – Mar 3, 1799 | Federalist | Theodore Sedgwick | 2 |
| 3 | Benjamin Goodhue | Federalist | Jun 11, 1796 – Nov 8, 1800 | Also elected to full term in 1796.Resigned. | 3 | 5th | 2 | Elected to finish Strong's term.Retired to run for the U.S. House of Representatives. | Jun 11, 1796 – Mar 3, 1799 | Federalist | Theodore Sedgwick | 2 |
| 3 | Benjamin Goodhue | Federalist | Jun 11, 1796 – Nov 8, 1800 | Also elected to full term in 1796.Resigned. | 3 | 6th | 3 | Elected in 1798.Resigned to become U.S. Secretary of War. | Mar 4, 1799 – May 30, 1800 | Federalist | Samuel Dexter | 3 |
| 3 | Benjamin Goodhue | Federalist | Jun 11, 1796 – Nov 8, 1800 | Also elected to full term in 1796.Resigned. | 3 | 6th | 3 | Vacant | May 31, 1800 – Jun 5, 1800 | Vacant | Vacant | Vacant |
| 3 | Benjamin Goodhue | Federalist | Jun 11, 1796 – Nov 8, 1800 | Also elected to full term in 1796.Resigned. | 3 | 6th | 3 | Elected to finish Dexter's term.Resigned. | Jun 6, 1800 – Mar 3, 1803 | Federalist | Dwight Foster | 4 |
| Vacant | Vacant | Vacant | Nov 8, 1800 – Nov 14, 1800 | Vacant | 3 | 6th | 3 | Elected to finish Dexter's term.Resigned. | Jun 6, 1800 – Mar 3, 1803 | Federalist | Dwight Foster | 4 |
| 4 | Jonathan Mason | Federalist | Nov 14, 1800 – Mar 3, 1803 | Elected to finish Goodhue's term. | 3 | 6th | 3 | Elected to finish Dexter's term.Resigned. | Jun 6, 1800 – Mar 3, 1803 | Federalist | Dwight Foster | 4 |
| 4 | Jonathan Mason | Federalist | Nov 14, 1800 – Mar 3, 1803 | Elected to finish Goodhue's term. | 3 | 7th | 3 | Elected to finish Dexter's term.Resigned. | Jun 6, 1800 – Mar 3, 1803 | Federalist | Dwight Foster | 4 |
| 4 | Jonathan Mason | Federalist | Nov 14, 1800 – Mar 3, 1803 | Elected to finish Goodhue's term. | 3 | 7th | 3 | Vacant | Mar 2, 1803 – Mar 3, 1803 | Vacant | Vacant | Vacant |
| 5 | John Quincy Adams | Federalist | Mar 4, 1803 – Jun 8, 1808 | Elected in 1803.Resigned, having lost re-election to the next term. | 4 | 8th | 3 | Elected to finish Dexter's term. | Mar 4, 1803 – Mar 3, 1811 | Federalist | Timothy Pickering | 5 |
| 5 | John Quincy Adams | Federalist | Mar 4, 1803 – Jun 8, 1808 | Elected in 1803.Resigned, having lost re-election to the next term. | 4 | 9th | 4 | Re-elected in 1805.Lost re-election. | Mar 4, 1803 – Mar 3, 1811 | Federalist | Timothy Pickering | 5 |
| 5 | John Quincy Adams | Federalist | Mar 4, 1803 – Jun 8, 1808 | Elected in 1803.Resigned, having lost re-election to the next term. | 4 | 10th | 4 | Re-elected in 1805.Lost re-election. | Mar 4, 1803 – Mar 3, 1811 | Federalist | Timothy Pickering | 5 |
| 6 | James Lloyd | Federalist | Jun 9, 1808 – May 1, 1813 | Elected to finish Adams's term, having already been elected to the next term. | 4 | 10th | 4 | Re-elected in 1805.Lost re-election. | Mar 4, 1803 – Mar 3, 1811 | Federalist | Timothy Pickering | 5 |
| 6 | James Lloyd | Federalist | Jun 9, 1808 – May 1, 1813 | Elected in 1808.Resigned. | 5 | 11th | 4 | Re-elected in 1805.Lost re-election. | Mar 4, 1803 – Mar 3, 1811 | Federalist | Timothy Pickering | 5 |
| 6 | James Lloyd | Federalist | Jun 9, 1808 – May 1, 1813 | Elected in 1808.Resigned. | 5 | 12th | 5 | State Senate failed to elect. | Mar 4, 1811 – Jun 28, 1811 | Vacant | Vacant | Vacant |
| 6 | James Lloyd | Federalist | Jun 9, 1808 – May 1, 1813 | Elected in 1808.Resigned. | 5 | 12th | 5 | Elected in 1811, to finish the vacant term.Retired or lost re-election. | Jun 29, 1811 – Mar 3, 1817 | Democratic- Republican | Joseph Bradley Varnum | 6 |
| 6 | James Lloyd | Federalist | Jun 9, 1808 – May 1, 1813 | Elected in 1808.Resigned. | 5 | 13th | 5 | Elected in 1811, to finish the vacant term.Retired or lost re-election. | Jun 29, 1811 – Mar 3, 1817 | Democratic- Republican | Joseph Bradley Varnum | 6 |
| Vacant | Vacant | Vacant | May 1, 1813 – May 5, 1813 | Vacant | 5 | 13th | 5 | Elected in 1811, to finish the vacant term.Retired or lost re-election. | Jun 29, 1811 – Mar 3, 1817 | Democratic- Republican | Joseph Bradley Varnum | 6 |
| 7 | Christopher Gore | Federalist | May 5, 1813 – May 30, 1816 | Appointed to finish Lloyd's term. | 5 | 13th | 5 | Elected in 1811, to finish the vacant term.Retired or lost re-election. | Jun 29, 1811 – Mar 3, 1817 | Democratic- Republican | Joseph Bradley Varnum | 6 |
| 7 | Christopher Gore | Federalist | May 5, 1813 – May 30, 1816 | Elected to full term in 1815.Resigned. | 6 | 14th | 5 | Elected in 1811, to finish the vacant term.Retired or lost re-election. | Jun 29, 1811 – Mar 3, 1817 | Democratic- Republican | Joseph Bradley Varnum | 6 |
| Vacant | Vacant | Vacant | May 31, 1816 – Jun 11, 1816 | Vacant | 6 | 14th | 5 | Elected in 1811, to finish the vacant term.Retired or lost re-election. | Jun 29, 1811 – Mar 3, 1817 | Democratic- Republican | Joseph Bradley Varnum | 6 |
| 8 | Eli P. Ashmun | Federalist | Jun 12, 1816 – May 10, 1818 | Elected to finish Gore's term.Resigned. | 6 | 14th | 5 | Elected in 1811, to finish the vacant term.Retired or lost re-election. | Jun 29, 1811 – Mar 3, 1817 | Democratic- Republican | Joseph Bradley Varnum | 6 |
| 8 | Eli P. Ashmun | Federalist | Jun 12, 1816 – May 10, 1818 | Elected to finish Gore's term.Resigned. | 6 | 15th | 6 | Elected in 1816.Resigned to run for Mayor of Boston. | Mar 4, 1817 – May 30, 1822 | Federalist | Harrison Gray Otis | 7 |
| Vacant | Vacant | Vacant | May 11, 1818 – Jun 4, 1818 | Vacant | 6 | 15th | 6 | Elected in 1816.Resigned to run for Mayor of Boston. | Mar 4, 1817 – May 30, 1822 | Federalist | Harrison Gray Otis | 7 |
| 9 | Prentiss Mellen | Federalist | Jun 5, 1818 – May 15, 1820 | Elected to finish Gore's term.Resigned to become Chief Justice of Maine. | 6 | 15th | 6 | Elected in 1816.Resigned to run for Mayor of Boston. | Mar 4, 1817 – May 30, 1822 | Federalist | Harrison Gray Otis | 7 |
| 9 | Prentiss Mellen | Federalist | Jun 5, 1818 – May 15, 1820 | Elected to finish Gore's term.Resigned to become Chief Justice of Maine. | 6 | 16th | 6 | Elected in 1816.Resigned to run for Mayor of Boston. | Mar 4, 1817 – May 30, 1822 | Federalist | Harrison Gray Otis | 7 |
| Vacant | Vacant | Vacant | May 16, 1820 – Jun 12, 1820 | Vacant | 6 | 16th | 6 | Elected in 1816.Resigned to run for Mayor of Boston. | Mar 4, 1817 – May 30, 1822 | Federalist | Harrison Gray Otis | 7 |
| 10 | Elijah H. Mills | Federalist | Jun 12, 1820 – Mar 3, 1827 | Elected to finish Gore's term. | 6 | 16th | 6 | Elected in 1816.Resigned to run for Mayor of Boston. | Mar 4, 1817 – May 30, 1822 | Federalist | Harrison Gray Otis | 7 |
| 10 | Elijah H. Mills | Federalist | Jun 12, 1820 – Mar 3, 1827 | Re-elected in 1820.Lost re-election in 1826. | 7 | 17th | 6 | Elected in 1816.Resigned to run for Mayor of Boston. | Mar 4, 1817 – May 30, 1822 | Federalist | Harrison Gray Otis | 7 |
| 10 | Elijah H. Mills | Federalist | Jun 12, 1820 – Mar 3, 1827 | Re-elected in 1820.Lost re-election in 1826. | 7 | 17th | 6 | Vacant | May 30, 1822 – Jun 5, 1822 | Vacant | Vacant | Vacant |
| 10 | Elijah H. Mills | Federalist | Jun 12, 1820 – Mar 3, 1827 | Re-elected in 1820.Lost re-election in 1826. | 7 | 17th | 6 | Elected to finish Otis's term. | Jun 5, 1822 – May 23, 1826 | Federalist | James Lloyd | 8 |
| 10 | Elijah H. Mills | Federalist | Jun 12, 1820 – Mar 3, 1827 | Re-elected in 1820.Lost re-election in 1826. | 7 | 18th | 7 | Re-elected in 1822.Resigned. | Jun 5, 1822 – May 23, 1826 | Federalist | James Lloyd | 8 |
| 10 | Elijah H. Mills | National Republican | Jun 12, 1820 – Mar 3, 1827 | Re-elected in 1820.Lost re-election in 1826. | 7 | 19th | 7 | Re-elected in 1822.Resigned. | Jun 5, 1822 – May 23, 1826 | National Republican | James Lloyd | 8 |
| 10 | Elijah H. Mills | National Republican | Jun 12, 1820 – Mar 3, 1827 | Re-elected in 1820.Lost re-election in 1826. | 7 | 19th | 7 | Vacant | May 23, 1826 – May 31, 1826 | Vacant | Vacant | Vacant |
| 10 | Elijah H. Mills | National Republican | Jun 12, 1820 – Mar 3, 1827 | Re-elected in 1820.Lost re-election in 1826. | 7 | 19th | 7 | Elected to finish Lloyd's term. | May 31, 1826 – Mar 3, 1835 | National Republican | Nathaniel Silsbee | 9 |
| Vacant | Vacant | Vacant | Mar 4, 1827 – Jun 8, 1827 | Vacant | 8 | 20th | 7 | Elected to finish Lloyd's term. | May 31, 1826 – Mar 3, 1835 | National Republican | Nathaniel Silsbee | 9 |
| 11 | Daniel Webster | National Republican | Jun 8, 1827 – Feb 22, 1841 | Elected late in 1827. | 8 | 20th | 7 | Elected to finish Lloyd's term. | May 31, 1826 – Mar 3, 1835 | National Republican | Nathaniel Silsbee | 9 |
| 11 | Daniel Webster | National Republican | Jun 8, 1827 – Feb 22, 1841 | Elected late in 1827. | 8 | 21st | 8 | Re-elected in 1828.Retired. | May 31, 1826 – Mar 3, 1835 | National Republican | Nathaniel Silsbee | 9 |
| 11 | Daniel Webster | National Republican | Jun 8, 1827 – Feb 22, 1841 | Elected late in 1827. | 8 | 22nd | 8 | Re-elected in 1828.Retired. | May 31, 1826 – Mar 3, 1835 | National Republican | Nathaniel Silsbee | 9 |
| 11 | Daniel Webster | National Republican | Jun 8, 1827 – Feb 22, 1841 | Re-elected in 1833. | 9 | 23rd | 8 | Re-elected in 1828.Retired. | May 31, 1826 – Mar 3, 1835 | National Republican | Nathaniel Silsbee | 9 |
| 11 | Daniel Webster | National Republican | Jun 8, 1827 – Feb 22, 1841 | Re-elected in 1833. | 9 | 24th | 9 | Elected in 1835.Resigned to become Governor of Massachusetts. | Mar 4, 1835 – Jan 5, 1841 | National Republican | John Davis | 10 |
| 11 | Daniel Webster | Whig | Jun 8, 1827 – Feb 22, 1841 | Re-elected in 1833. | 9 | 25th | 9 | Elected in 1835.Resigned to become Governor of Massachusetts. | Mar 4, 1835 – Jan 5, 1841 | Whig | John Davis | 10 |
| 11 | Daniel Webster | Whig | Jun 8, 1827 – Feb 22, 1841 | Re-elected in 1839.Resigned to become U.S. Secretary of State. | 10 | 26th | 9 | Elected in 1835.Resigned to become Governor of Massachusetts. | Mar 4, 1835 – Jan 5, 1841 | Whig | John Davis | 10 |
| 11 | Daniel Webster | Whig | Jun 8, 1827 – Feb 22, 1841 | Re-elected in 1839.Resigned to become U.S. Secretary of State. | 10 | 26th | 9 | Vacant | Jan 5, 1841 – Jan 13, 1841 | Vacant | Vacant | Vacant |
| 11 | Daniel Webster | Whig | Jun 8, 1827 – Feb 22, 1841 | Re-elected in 1839.Resigned to become U.S. Secretary of State. | 10 | 26th | 9 | Elected to finish Davis's term. | Jan 13, 1841 – Mar 16, 1845 | Whig | Isaac C. Bates | 11 |
| 12 | Rufus Choate | Whig | Feb 23, 1841 – Mar 3, 1845 | Elected to finish Webster's term.Retired. | 10 | 26th | 9 | Elected to finish Davis's term. | Jan 13, 1841 – Mar 16, 1845 | Whig | Isaac C. Bates | 11 |
| 12 | Rufus Choate | Whig | Feb 23, 1841 – Mar 3, 1845 | Elected to finish Webster's term.Retired. | 10 | 27th | 10 | Elected to full term in 1841.Died. | Jan 13, 1841 – Mar 16, 1845 | Whig | Isaac C. Bates | 11 |
| 12 | Rufus Choate | Whig | Feb 23, 1841 – Mar 3, 1845 | Elected to finish Webster's term.Retired. | 10 | 28th | 10 | Elected to full term in 1841.Died. | Jan 13, 1841 – Mar 16, 1845 | Whig | Isaac C. Bates | 11 |
| 13 | Daniel Webster | Whig | Mar 4, 1845 – Jul 22, 1850 | Elected in 1845.Resigned to become U.S. Secretary of State again. | 11 | 29th | 10 | Elected to full term in 1841.Died. | Jan 13, 1841 – Mar 16, 1845 | Whig | Isaac C. Bates | 11 |
| 13 | Daniel Webster | Whig | Mar 4, 1845 – Jul 22, 1850 | Elected in 1845.Resigned to become U.S. Secretary of State again. | 11 | 29th | 10 | Vacant | Mar 16, 1845 – Mar 24, 1845 | Vacant | Vacant | Vacant |
| 13 | Daniel Webster | Whig | Mar 4, 1845 – Jul 22, 1850 | Elected in 1845.Resigned to become U.S. Secretary of State again. | 11 | 29th | 10 | Elected to finish Bates's term. | Mar 24, 1845 – Mar 3, 1853 | Whig | John Davis | 12 |
| 13 | Daniel Webster | Whig | Mar 4, 1845 – Jul 22, 1850 | Elected in 1845.Resigned to become U.S. Secretary of State again. | 11 | 30th | 11 | Re-elected in 1847.Retired. | Mar 24, 1845 – Mar 3, 1853 | Whig | John Davis | 12 |
| 13 | Daniel Webster | Whig | Mar 4, 1845 – Jul 22, 1850 | Elected in 1845.Resigned to become U.S. Secretary of State again. | 11 | 31st | 11 | Re-elected in 1847.Retired. | Mar 24, 1845 – Mar 3, 1853 | Whig | John Davis | 12 |
| Vacant | Vacant | Vacant | Jul 23, 1850 – Jul 30, 1850 | Vacant | 11 | 31st | 11 | Re-elected in 1847.Retired. | Mar 24, 1845 – Mar 3, 1853 | Whig | John Davis | 12 |
| 14 | Robert C. Winthrop | Whig | Jul 30, 1850 – Feb 1, 1851 | Appointed to continue Webster's term.Lost election to finish Webster's term. | 11 | 31st | 11 | Re-elected in 1847.Retired. | Mar 24, 1845 – Mar 3, 1853 | Whig | John Davis | 12 |
| 15 | Robert Rantoul Jr. | Democratic | Feb 1, 1851 – Mar 3, 1851 | Elected to finish Webster's term.Retired. | 11 | 31st | 11 | Re-elected in 1847.Retired. | Mar 24, 1845 – Mar 3, 1853 | Whig | John Davis | 12 |
| Vacant | Vacant | Vacant | Mar 4, 1851 – Apr 24, 1851 | The legislature initially deadlocked on who should succeed Daniel Webster. Sumner was eventually elected late. | 12 | 32nd | 11 | Re-elected in 1847.Retired. | Mar 24, 1845 – Mar 3, 1853 | Whig | John Davis | 12 |
| 16 | Charles Sumner | Free Soil | Apr 24, 1851 – Mar 11, 1874 | The legislature initially deadlocked on who should succeed Daniel Webster. Sumner was eventually elected late. | 12 | 32nd | 11 | Re-elected in 1847.Retired. | Mar 24, 1845 – Mar 3, 1853 | Whig | John Davis | 12 |
| 16 | Charles Sumner | Free Soil | Apr 24, 1851 – Mar 11, 1874 | The legislature initially deadlocked on who should succeed Daniel Webster. Sumner was eventually elected late. | 12 | 33rd | 12 | Elected in 1853.Resigned. | Mar 4, 1853 – Jun 1, 1854 | Whig | Edward Everett | 13 |
| 16 | Charles Sumner | Free Soil | Apr 24, 1851 – Mar 11, 1874 | The legislature initially deadlocked on who should succeed Daniel Webster. Sumner was eventually elected late. | 12 | 33rd | 12 | Vacant | Jun 1, 1854 – Jun 3, 1854 | Vacant | Vacant | Vacant |
| 16 | Charles Sumner | Free Soil | Apr 24, 1851 – Mar 11, 1874 | The legislature initially deadlocked on who should succeed Daniel Webster. Sumner was eventually elected late. | 12 | 33rd | 12 | Appointed to continue Everett's term.Successor was elected. | Jun 3, 1854 – Jan 31, 1855 | Whig | Julius Rockwell | 14 |
| 16 | Charles Sumner | Free Soil | Apr 24, 1851 – Mar 11, 1874 | The legislature initially deadlocked on who should succeed Daniel Webster. Sumner was eventually elected late. | 12 | 33rd | 12 | Elected to finish Everett's term. | Jan 31, 1855 – Mar 3, 1873 | Know Nothing | Henry Wilson | 15 |
| 16 | Charles Sumner | Free Soil | Apr 24, 1851 – Mar 11, 1874 | The legislature initially deadlocked on who should succeed Daniel Webster. Sumner was eventually elected late. | 12 | 34th | 12 | Elected to finish Everett's term. | Jan 31, 1855 – Mar 3, 1873 | Republican | Henry Wilson | 15 |
| 16 | Charles Sumner | Republican | Apr 24, 1851 – Mar 11, 1874 | Re-elected in 1857. | 13 | 35th | 12 | Elected to finish Everett's term. | Jan 31, 1855 – Mar 3, 1873 | Republican | Henry Wilson | 15 |
| 16 | Charles Sumner | Republican | Apr 24, 1851 – Mar 11, 1874 | Re-elected in 1857. | 13 | 36th | 13 | Re-elected in 1859. | Jan 31, 1855 – Mar 3, 1873 | Republican | Henry Wilson | 15 |
| 16 | Charles Sumner | Republican | Apr 24, 1851 – Mar 11, 1874 | Re-elected in 1857. | 13 | 37th | 13 | Re-elected in 1859. | Jan 31, 1855 – Mar 3, 1873 | Republican | Henry Wilson | 15 |
| 16 | Charles Sumner | Republican | Apr 24, 1851 – Mar 11, 1874 | Re-elected in 1863. | 14 | 38th | 13 | Re-elected in 1859. | Jan 31, 1855 – Mar 3, 1873 | Republican | Henry Wilson | 15 |
| 16 | Charles Sumner | Republican | Apr 24, 1851 – Mar 11, 1874 | Re-elected in 1863. | 14 | 39th | 14 | Re-elected in 1865. | Jan 31, 1855 – Mar 3, 1873 | Republican | Henry Wilson | 15 |
| 16 | Charles Sumner | Republican | Apr 24, 1851 – Mar 11, 1874 | Re-elected in 1863. | 14 | 40th | 14 | Re-elected in 1865. | Jan 31, 1855 – Mar 3, 1873 | Republican | Henry Wilson | 15 |
| 16 | Charles Sumner | Republican | Apr 24, 1851 – Mar 11, 1874 | Re-elected in 1869.Died. | 15 | 41st | 14 | Re-elected in 1865. | Jan 31, 1855 – Mar 3, 1873 | Republican | Henry Wilson | 15 |
| 16 | Charles Sumner | Republican | Apr 24, 1851 – Mar 11, 1874 | Re-elected in 1869.Died. | 15 | 42nd | 15 | Re-elected in 1871.Resigned to become the Vice President of the United States. | Jan 31, 1855 – Mar 3, 1873 | Republican | Henry Wilson | 15 |
| 16 | Charles Sumner | Liberal Republican | Apr 24, 1851 – Mar 11, 1874 | Re-elected in 1869.Died. | 15 | 43rd | 15 | Vacant | Mar 3, 1873 – Mar 17, 1873 | Vacant | Vacant | Vacant |
| 16 | Charles Sumner | Liberal Republican | Apr 24, 1851 – Mar 11, 1874 | Re-elected in 1869.Died. | 15 | 43rd | 15 | Elected to finish Wilson's term.Lost renomination. | Mar 17, 1873 – Mar 3, 1877 | Republican | George S. Boutwell | 16 |
| Vacant | Vacant | Vacant | Mar 12, 1874 – Apr 16, 1874 | Vacant | 15 | 43rd | 15 | Elected to finish Wilson's term.Lost renomination. | Mar 17, 1873 – Mar 3, 1877 | Republican | George S. Boutwell | 16 |
| 17 | William B. Washburn | Republican | Apr 17, 1874 – Mar 3, 1875 | Elected to finish Sumner's term.Retired. | 15 | 43rd | 15 | Elected to finish Wilson's term.Lost renomination. | Mar 17, 1873 – Mar 3, 1877 | Republican | George S. Boutwell | 16 |
| 18 | Henry L. Dawes | Republican | Mar 4, 1875 – Mar 3, 1893 | Elected in 1875. | 16 | 44th | 15 | Elected to finish Wilson's term.Lost renomination. | Mar 17, 1873 – Mar 3, 1877 | Republican | George S. Boutwell | 16 |
| 18 | Henry L. Dawes | Republican | Mar 4, 1875 – Mar 3, 1893 | Elected in 1875. | 16 | 45th | 16 | Elected in 1877. | Mar 4, 1877 – Sep 30, 1904 | Republican | George F. Hoar | 17 |
| 18 | Henry L. Dawes | Republican | Mar 4, 1875 – Mar 3, 1893 | Elected in 1875. | 16 | 46th | 16 | Elected in 1877. | Mar 4, 1877 – Sep 30, 1904 | Republican | George F. Hoar | 17 |
| 18 | Henry L. Dawes | Republican | Mar 4, 1875 – Mar 3, 1893 | Re-elected in 1881. | 17 | 47th | 16 | Elected in 1877. | Mar 4, 1877 – Sep 30, 1904 | Republican | George F. Hoar | 17 |
| 18 | Henry L. Dawes | Republican | Mar 4, 1875 – Mar 3, 1893 | Re-elected in 1881. | 17 | 48th | 17 | Re-elected in 1883. | Mar 4, 1877 – Sep 30, 1904 | Republican | George F. Hoar | 17 |
| 18 | Henry L. Dawes | Republican | Mar 4, 1875 – Mar 3, 1893 | Re-elected in 1881. | 17 | 49th | 17 | Re-elected in 1883. | Mar 4, 1877 – Sep 30, 1904 | Republican | George F. Hoar | 17 |
| 18 | Henry L. Dawes | Republican | Mar 4, 1875 – Mar 3, 1893 | Re-elected in 1887.Retired. | 18 | 50th | 17 | Re-elected in 1883. | Mar 4, 1877 – Sep 30, 1904 | Republican | George F. Hoar | 17 |
| 18 | Henry L. Dawes | Republican | Mar 4, 1875 – Mar 3, 1893 | Re-elected in 1887.Retired. | 18 | 51st | 18 | Re-elected in 1889. | Mar 4, 1877 – Sep 30, 1904 | Republican | George F. Hoar | 17 |
| 18 | Henry L. Dawes | Republican | Mar 4, 1875 – Mar 3, 1893 | Re-elected in 1887.Retired. | 18 | 52nd | 18 | Re-elected in 1889. | Mar 4, 1877 – Sep 30, 1904 | Republican | George F. Hoar | 17 |
| 19 | Henry Cabot Lodge | Republican | Mar 4, 1893 – Nov 9, 1924 | Elected in 1893. | 19 | 53rd | 18 | Re-elected in 1889. | Mar 4, 1877 – Sep 30, 1904 | Republican | George F. Hoar | 17 |
| 19 | Henry Cabot Lodge | Republican | Mar 4, 1893 – Nov 9, 1924 | Elected in 1893. | 19 | 54th | 19 | Re-elected in 1895. | Mar 4, 1877 – Sep 30, 1904 | Republican | George F. Hoar | 17 |
| 19 | Henry Cabot Lodge | Republican | Mar 4, 1893 – Nov 9, 1924 | Elected in 1893. | 19 | 55th | 19 | Re-elected in 1895. | Mar 4, 1877 – Sep 30, 1904 | Republican | George F. Hoar | 17 |
| 19 | Henry Cabot Lodge | Republican | Mar 4, 1893 – Nov 9, 1924 | Re-elected in 1899. | 20 | 56th | 19 | Re-elected in 1895. | Mar 4, 1877 – Sep 30, 1904 | Republican | George F. Hoar | 17 |
| 19 | Henry Cabot Lodge | Republican | Mar 4, 1893 – Nov 9, 1924 | Re-elected in 1899. | 20 | 57th | 20 | Re-elected in 1901.Died. | Mar 4, 1877 – Sep 30, 1904 | Republican | George F. Hoar | 17 |
| 19 | Henry Cabot Lodge | Republican | Mar 4, 1893 – Nov 9, 1924 | Re-elected in 1899. | 20 | 58th | 20 | Re-elected in 1901.Died. | Mar 4, 1877 – Sep 30, 1904 | Republican | George F. Hoar | 17 |
| 19 | Henry Cabot Lodge | Republican | Mar 4, 1893 – Nov 9, 1924 | Re-elected in 1899. | 20 | 58th | 20 | Vacant | Sep 30, 1904 – Oct 12, 1904 | Vacant | Vacant | Vacant |
| 19 | Henry Cabot Lodge | Republican | Mar 4, 1893 – Nov 9, 1924 | Re-elected in 1899. | 20 | 58th | 20 | Appointed to continue Hoar's term.Elected to finish Hoar's term. | Oct 12, 1904 – Mar 3, 1913 | Republican | Winthrop M. Crane | 18 |
| 19 | Henry Cabot Lodge | Republican | Mar 4, 1893 – Nov 9, 1924 | Re-elected in 1905. | 21 | 59th | 20 | Appointed to continue Hoar's term.Elected to finish Hoar's term. | Oct 12, 1904 – Mar 3, 1913 | Republican | Winthrop M. Crane | 18 |
| 19 | Henry Cabot Lodge | Republican | Mar 4, 1893 – Nov 9, 1924 | Re-elected in 1905. | 21 | 60th | 21 | Re-elected in 1907.Retired. | Oct 12, 1904 – Mar 3, 1913 | Republican | Winthrop M. Crane | 18 |
| 19 | Henry Cabot Lodge | Republican | Mar 4, 1893 – Nov 9, 1924 | Re-elected in 1905. | 21 | 61st | 21 | Re-elected in 1907.Retired. | Oct 12, 1904 – Mar 3, 1913 | Republican | Winthrop M. Crane | 18 |
| 19 | Henry Cabot Lodge | Republican | Mar 4, 1893 – Nov 9, 1924 | Re-elected in 1911. | 22 | 62nd | 21 | Re-elected in 1907.Retired. | Oct 12, 1904 – Mar 3, 1913 | Republican | Winthrop M. Crane | 18 |
| 19 | Henry Cabot Lodge | Republican | Mar 4, 1893 – Nov 9, 1924 | Re-elected in 1911. | 22 | 63rd | 22 | Elected in 1913.Lost re-election. | Mar 4, 1913 – Mar 3, 1919 | Republican | John W. Weeks | 19 |
| 19 | Henry Cabot Lodge | Republican | Mar 4, 1893 – Nov 9, 1924 | Re-elected in 1911. | 22 | 64th | 22 | Elected in 1913.Lost re-election. | Mar 4, 1913 – Mar 3, 1919 | Republican | John W. Weeks | 19 |
| 19 | Henry Cabot Lodge | Republican | Mar 4, 1893 – Nov 9, 1924 | Re-elected in 1916. | 23 | 65th | 22 | Elected in 1913.Lost re-election. | Mar 4, 1913 – Mar 3, 1919 | Republican | John W. Weeks | 19 |
| 19 | Henry Cabot Lodge | Republican | Mar 4, 1893 – Nov 9, 1924 | Re-elected in 1916. | 23 | 66th | 23 | Elected in 1918.Lost re-election. | Mar 4, 1919 – Mar 3, 1925 | Democratic | David I. Walsh | 20 |
| 19 | Henry Cabot Lodge | Republican | Mar 4, 1893 – Nov 9, 1924 | Re-elected in 1916. | 23 | 67th | 23 | Elected in 1918.Lost re-election. | Mar 4, 1919 – Mar 3, 1925 | Democratic | David I. Walsh | 20 |
| 19 | Henry Cabot Lodge | Republican | Mar 4, 1893 – Nov 9, 1924 | Re-elected in 1922.Died. | 24 | 68th | 23 | Elected in 1918.Lost re-election. | Mar 4, 1919 – Mar 3, 1925 | Democratic | David I. Walsh | 20 |
| Vacant | Vacant | Vacant | Nov 9, 1924 – Nov 13, 1924 | Vacant | 24 | 68th | 23 | Elected in 1918.Lost re-election. | Mar 4, 1919 – Mar 3, 1925 | Democratic | David I. Walsh | 20 |
| 20 | William M. Butler | Republican | Nov 13, 1924 – Dec 6, 1926 | Appointed to continue Lodge's term.Lost election to finish Lodge's term. | 24 | 68th | 23 | Elected in 1918.Lost re-election. | Mar 4, 1919 – Mar 3, 1925 | Democratic | David I. Walsh | 20 |
| 20 | William M. Butler | Republican | Nov 13, 1924 – Dec 6, 1926 | Appointed to continue Lodge's term.Lost election to finish Lodge's term. | 24 | 69th | 24 | Elected in 1924.Retired. | Mar 4, 1925 – Mar 3, 1931 | Republican | Frederick H. Gillett | 21 |
| 21 | David I. Walsh | Democratic | Dec 6, 1926 – Jan 3, 1947 | Elected to finish Lodge's term. | 24 | 69th | 24 | Elected in 1924.Retired. | Mar 4, 1925 – Mar 3, 1931 | Republican | Frederick H. Gillett | 21 |
| 21 | David I. Walsh | Democratic | Dec 6, 1926 – Jan 3, 1947 | Elected to finish Lodge's term. | 24 | 70th | 24 | Elected in 1924.Retired. | Mar 4, 1925 – Mar 3, 1931 | Republican | Frederick H. Gillett | 21 |
| 21 | David I. Walsh | Democratic | Dec 6, 1926 – Jan 3, 1947 | Re-elected in 1928. | 25 | 71st | 24 | Elected in 1924.Retired. | Mar 4, 1925 – Mar 3, 1931 | Republican | Frederick H. Gillett | 21 |
| 21 | David I. Walsh | Democratic | Dec 6, 1926 – Jan 3, 1947 | Re-elected in 1928. | 25 | 72nd | 25 | Elected in 1930.Retired. | Mar 4, 1931 – Jan 3, 1937 | Democratic | Marcus A. Coolidge | 22 |
| 21 | David I. Walsh | Democratic | Dec 6, 1926 – Jan 3, 1947 | Re-elected in 1928. | 25 | 73rd | 25 | Elected in 1930.Retired. | Mar 4, 1931 – Jan 3, 1937 | Democratic | Marcus A. Coolidge | 22 |
| 21 | David I. Walsh | Democratic | Dec 6, 1926 – Jan 3, 1947 | Re-elected in 1934. | 26 | 74th | 25 | Elected in 1930.Retired. | Mar 4, 1931 – Jan 3, 1937 | Democratic | Marcus A. Coolidge | 22 |
| 21 | David I. Walsh | Democratic | Dec 6, 1926 – Jan 3, 1947 | Re-elected in 1934. | 26 | 75th | 26 | Elected in 1936. | Jan 3, 1937 – Feb 3, 1944 | Republican | Henry Cabot Lodge Jr. | 23 |
| 21 | David I. Walsh | Democratic | Dec 6, 1926 – Jan 3, 1947 | Re-elected in 1934. | 26 | 76th | 26 | Elected in 1936. | Jan 3, 1937 – Feb 3, 1944 | Republican | Henry Cabot Lodge Jr. | 23 |
| 21 | David I. Walsh | Democratic | Dec 6, 1926 – Jan 3, 1947 | Re-elected in 1940.Lost re-election. | 27 | 77th | 26 | Elected in 1936. | Jan 3, 1937 – Feb 3, 1944 | Republican | Henry Cabot Lodge Jr. | 23 |
| 21 | David I. Walsh | Democratic | Dec 6, 1926 – Jan 3, 1947 | Re-elected in 1940.Lost re-election. | 27 | 78th | 27 | Re-elected in 1942.Resigned to return to active duty in the U.S. Army. | Jan 3, 1937 – Feb 3, 1944 | Republican | Henry Cabot Lodge Jr. | 23 |
| 21 | David I. Walsh | Democratic | Dec 6, 1926 – Jan 3, 1947 | Re-elected in 1940.Lost re-election. | 27 | 78th | 27 | Vacant | Feb 4, 1944 – Feb 7, 1944 | Vacant | Vacant | Vacant |
| 21 | David I. Walsh | Democratic | Dec 6, 1926 – Jan 3, 1947 | Re-elected in 1940.Lost re-election. | 27 | 78th | 27 | Appointed to continue Lodge's term.Did not run for election to finish the term. | Feb 8, 1944 – Dec 19, 1944 | Republican | Sinclair Weeks | 24 |
| 21 | David I. Walsh | Democratic | Dec 6, 1926 – Jan 3, 1947 | Re-elected in 1940.Lost re-election. | 27 | 78th | 27 | Elected to finish Lodge's term.Didn't take seat until Jan 4, 1945 in order to remain Governor of Massachusetts. | Dec 19, 1944 – Jan 3, 1967 | Republican | Leverett Saltonstall | 25 |
| 21 | David I. Walsh | Democratic | Dec 6, 1926 – Jan 3, 1947 | Re-elected in 1940.Lost re-election. | 27 | 79th | 27 | Elected to finish Lodge's term.Didn't take seat until Jan 4, 1945 in order to remain Governor of Massachusetts. | Dec 19, 1944 – Jan 3, 1967 | Republican | Leverett Saltonstall | 25 |
| 22 | Henry Cabot Lodge Jr. | Republican | Jan 3, 1947 – Jan 3, 1953 | Elected in 1946.Lost re-election. | 28 | 80th | 27 | Elected to finish Lodge's term.Didn't take seat until Jan 4, 1945 in order to remain Governor of Massachusetts. | Dec 19, 1944 – Jan 3, 1967 | Republican | Leverett Saltonstall | 25 |
| 22 | Henry Cabot Lodge Jr. | Republican | Jan 3, 1947 – Jan 3, 1953 | Elected in 1946.Lost re-election. | 28 | 81st | 28 | Re-elected in 1948. | Dec 19, 1944 – Jan 3, 1967 | Republican | Leverett Saltonstall | 25 |
| 22 | Henry Cabot Lodge Jr. | Republican | Jan 3, 1947 – Jan 3, 1953 | Elected in 1946.Lost re-election. | 28 | 82nd | 28 | Re-elected in 1948. | Dec 19, 1944 – Jan 3, 1967 | Republican | Leverett Saltonstall | 25 |
| 23 | John F. Kennedy | Democratic | Jan 3, 1953 – Dec 22, 1960 | Elected in 1952. | 29 | 83rd | 28 | Re-elected in 1948. | Dec 19, 1944 – Jan 3, 1967 | Republican | Leverett Saltonstall | 25 |
| 23 | John F. Kennedy | Democratic | Jan 3, 1953 – Dec 22, 1960 | Elected in 1952. | 29 | 84th | 29 | Re-elected in 1954. | Dec 19, 1944 – Jan 3, 1967 | Republican | Leverett Saltonstall | 25 |
| 23 | John F. Kennedy | Democratic | Jan 3, 1953 – Dec 22, 1960 | Elected in 1952. | 29 | 85th | 29 | Re-elected in 1954. | Dec 19, 1944 – Jan 3, 1967 | Republican | Leverett Saltonstall | 25 |
| 23 | John F. Kennedy | Democratic | Jan 3, 1953 – Dec 22, 1960 | Re-elected in 1958.Resigned to become U.S. President. | 30 | 86th | 29 | Re-elected in 1954. | Dec 19, 1944 – Jan 3, 1967 | Republican | Leverett Saltonstall | 25 |
| Vacant | Vacant | Vacant | Dec 22, 1960 – Dec 27, 1960 | Vacant | 30 | 86th | 29 | Re-elected in 1954. | Dec 19, 1944 – Jan 3, 1967 | Republican | Leverett Saltonstall | 25 |
| 24 | Benjamin Smith | Democratic | Dec 27, 1960 – Nov 7, 1962 | Appointed to continue John Kennedy's term.Did not run for election to finish the term. | 30 | 86th | 29 | Re-elected in 1954. | Dec 19, 1944 – Jan 3, 1967 | Republican | Leverett Saltonstall | 25 |
| 24 | Benjamin Smith | Democratic | Dec 27, 1960 – Nov 7, 1962 | Appointed to continue John Kennedy's term.Did not run for election to finish the term. | 30 | 87th | 30 | Re-elected in 1960.Retired. | Dec 19, 1944 – Jan 3, 1967 | Republican | Leverett Saltonstall | 25 |
| 25 | Ted Kennedy | Democratic | Nov 7, 1962 – Aug 25, 2009 | Elected to finish his brother's term. | 30 | 87th | 30 | Re-elected in 1960.Retired. | Dec 19, 1944 – Jan 3, 1967 | Republican | Leverett Saltonstall | 25 |
| 25 | Ted Kennedy | Democratic | Nov 7, 1962 – Aug 25, 2009 | Elected to finish his brother's term. | 30 | 88th | 30 | Re-elected in 1960.Retired. | Dec 19, 1944 – Jan 3, 1967 | Republican | Leverett Saltonstall | 25 |
| 25 | Ted Kennedy | Democratic | Nov 7, 1962 – Aug 25, 2009 | Re-elected in 1964. | 31 | 89th | 30 | Re-elected in 1960.Retired. | Dec 19, 1944 – Jan 3, 1967 | Republican | Leverett Saltonstall | 25 |
| 25 | Ted Kennedy | Democratic | Nov 7, 1962 – Aug 25, 2009 | Re-elected in 1964. | 31 | 90th | 31 | Elected in 1966. | Jan 3, 1967 – Jan 3, 1979 | Republican | Edward Brooke | 26 |
| 25 | Ted Kennedy | Democratic | Nov 7, 1962 – Aug 25, 2009 | Re-elected in 1964. | 31 | 91st | 31 | Elected in 1966. | Jan 3, 1967 – Jan 3, 1979 | Republican | Edward Brooke | 26 |
| 25 | Ted Kennedy | Democratic | Nov 7, 1962 – Aug 25, 2009 | Re-elected in 1970. | 32 | 92nd | 31 | Elected in 1966. | Jan 3, 1967 – Jan 3, 1979 | Republican | Edward Brooke | 26 |
| 25 | Ted Kennedy | Democratic | Nov 7, 1962 – Aug 25, 2009 | Re-elected in 1970. | 32 | 93rd | 32 | Re-elected in 1972.Lost re-election. | Jan 3, 1967 – Jan 3, 1979 | Republican | Edward Brooke | 26 |
| 25 | Ted Kennedy | Democratic | Nov 7, 1962 – Aug 25, 2009 | Re-elected in 1970. | 32 | 94th | 32 | Re-elected in 1972.Lost re-election. | Jan 3, 1967 – Jan 3, 1979 | Republican | Edward Brooke | 26 |
| 25 | Ted Kennedy | Democratic | Nov 7, 1962 – Aug 25, 2009 | Re-elected in 1976. | 33 | 95th | 32 | Re-elected in 1972.Lost re-election. | Jan 3, 1967 – Jan 3, 1979 | Republican | Edward Brooke | 26 |
| 25 | Ted Kennedy | Democratic | Nov 7, 1962 – Aug 25, 2009 | Re-elected in 1976. | 33 | 96th | 33 | Elected in 1978.Retired and resigned early to give successor preferential seniority. | Jan 3, 1979 – Jan 2, 1985 | Democratic | Paul Tsongas | 27 |
| 25 | Ted Kennedy | Democratic | Nov 7, 1962 – Aug 25, 2009 | Re-elected in 1976. | 33 | 97th | 33 | Elected in 1978.Retired and resigned early to give successor preferential seniority. | Jan 3, 1979 – Jan 2, 1985 | Democratic | Paul Tsongas | 27 |
| 25 | Ted Kennedy | Democratic | Nov 7, 1962 – Aug 25, 2009 | Re-elected in 1982. | 34 | 98th | 33 | Elected in 1978.Retired and resigned early to give successor preferential seniority. | Jan 3, 1979 – Jan 2, 1985 | Democratic | Paul Tsongas | 27 |
| 25 | Ted Kennedy | Democratic | Nov 7, 1962 – Aug 25, 2009 | Re-elected in 1982. | 34 | 98th | 33 | Appointed to finish Tsongas's term, having already been elected to the next term. | Jan 2, 1985 – Feb 1, 2013 | Democratic | John Kerry | 28 |
| 25 | Ted Kennedy | Democratic | Nov 7, 1962 – Aug 25, 2009 | Re-elected in 1982. | 34 | 99th | 34 | Elected in 1984. | Jan 2, 1985 – Feb 1, 2013 | Democratic | John Kerry | 28 |
| 25 | Ted Kennedy | Democratic | Nov 7, 1962 – Aug 25, 2009 | Re-elected in 1982. | 34 | 100th | 34 | Elected in 1984. | Jan 2, 1985 – Feb 1, 2013 | Democratic | John Kerry | 28 |
| 25 | Ted Kennedy | Democratic | Nov 7, 1962 – Aug 25, 2009 | Re-elected in 1988. | 35 | 101st | 34 | Elected in 1984. | Jan 2, 1985 – Feb 1, 2013 | Democratic | John Kerry | 28 |
| 25 | Ted Kennedy | Democratic | Nov 7, 1962 – Aug 25, 2009 | Re-elected in 1988. | 35 | 102nd | 35 | Re-elected in 1990. | Jan 2, 1985 – Feb 1, 2013 | Democratic | John Kerry | 28 |
| 25 | Ted Kennedy | Democratic | Nov 7, 1962 – Aug 25, 2009 | Re-elected in 1988. | 35 | 103rd | 35 | Re-elected in 1990. | Jan 2, 1985 – Feb 1, 2013 | Democratic | John Kerry | 28 |
| 25 | Ted Kennedy | Democratic | Nov 7, 1962 – Aug 25, 2009 | Re-elected in 1994. | 36 | 104th | 35 | Re-elected in 1990. | Jan 2, 1985 – Feb 1, 2013 | Democratic | John Kerry | 28 |
| 25 | Ted Kennedy | Democratic | Nov 7, 1962 – Aug 25, 2009 | Re-elected in 1994. | 36 | 105th | 36 | Re-elected in 1996. | Jan 2, 1985 – Feb 1, 2013 | Democratic | John Kerry | 28 |
| 25 | Ted Kennedy | Democratic | Nov 7, 1962 – Aug 25, 2009 | Re-elected in 1994. | 36 | 106th | 36 | Re-elected in 1996. | Jan 2, 1985 – Feb 1, 2013 | Democratic | John Kerry | 28 |
| 25 | Ted Kennedy | Democratic | Nov 7, 1962 – Aug 25, 2009 | Re-elected in 2000. | 37 | 107th | 36 | Re-elected in 1996. | Jan 2, 1985 – Feb 1, 2013 | Democratic | John Kerry | 28 |
| 25 | Ted Kennedy | Democratic | Nov 7, 1962 – Aug 25, 2009 | Re-elected in 2000. | 37 | 108th | 37 | Re-elected in 2002. | Jan 2, 1985 – Feb 1, 2013 | Democratic | John Kerry | 28 |
| 25 | Ted Kennedy | Democratic | Nov 7, 1962 – Aug 25, 2009 | Re-elected in 2000. | 37 | 109th | 37 | Re-elected in 2002. | Jan 2, 1985 – Feb 1, 2013 | Democratic | John Kerry | 28 |
| 25 | Ted Kennedy | Democratic | Nov 7, 1962 – Aug 25, 2009 | Re-elected in 2006.Died. | 38 | 110th | 37 | Re-elected in 2002. | Jan 2, 1985 – Feb 1, 2013 | Democratic | John Kerry | 28 |
| 25 | Ted Kennedy | Democratic | Nov 7, 1962 – Aug 25, 2009 | Re-elected in 2006.Died. | 38 | 111th | 38 | Re-elected in 2008.Resigned to become U.S. Secretary of State. | Jan 2, 1985 – Feb 1, 2013 | Democratic | John Kerry | 28 |
| Vacant | Vacant | Vacant | Aug 25, 2009 – Sep 24, 2009 | Vacant | 38 | 111th | 38 | Re-elected in 2008.Resigned to become U.S. Secretary of State. | Jan 2, 1985 – Feb 1, 2013 | Democratic | John Kerry | 28 |
| 26 | Paul G. Kirk | Democratic | Sep 24, 2009 – Feb 4, 2010 | Appointed to continue Ted Kennedy's term.Did not run for election to finish the term. | 38 | 111th | 38 | Re-elected in 2008.Resigned to become U.S. Secretary of State. | Jan 2, 1985 – Feb 1, 2013 | Democratic | John Kerry | 28 |
| 27 | Scott Brown | Republican | Feb 4, 2010 – Jan 3, 2013 | Elected to finish Ted Kennedy's term.Lost re-election. | 38 | 111th | 38 | Re-elected in 2008.Resigned to become U.S. Secretary of State. | Jan 2, 1985 – Feb 1, 2013 | Democratic | John Kerry | 28 |
| 27 | Scott Brown | Republican | Feb 4, 2010 – Jan 3, 2013 | Elected to finish Ted Kennedy's term.Lost re-election. | 38 | 112th | 38 | Re-elected in 2008.Resigned to become U.S. Secretary of State. | Jan 2, 1985 – Feb 1, 2013 | Democratic | John Kerry | 28 |
| 28 | Elizabeth Warren | Democratic | Jan 3, 2013 – present | Elected in 2012. | 39 | 113th | 38 | Re-elected in 2008.Resigned to become U.S. Secretary of State. | Jan 2, 1985 – Feb 1, 2013 | Democratic | John Kerry | 28 |
| 28 | Elizabeth Warren | Democratic | Jan 3, 2013 – present | Elected in 2012. | 39 | 113th | 38 | Appointed to continue Kerry's term.Did not run for election to finish the term. | Feb 1, 2013 – Jul 15, 2013 | Democratic | Mo Cowan | 29 |
| 28 | Elizabeth Warren | Democratic | Jan 3, 2013 – present | Elected in 2012. | 39 | 113th | 38 | Elected to finish Kerry's term. | Jul 16, 2013 – present | Democratic | Ed Markey | 30 |
| 28 | Elizabeth Warren | Democratic | Jan 3, 2013 – present | Elected in 2012. | 39 | 114th | 39 | Re-elected in 2014. | Jul 16, 2013 – present | Democratic | Ed Markey | 30 |
| 28 | Elizabeth Warren | Democratic | Jan 3, 2013 – present | Elected in 2012. | 39 | 115th | 39 | Re-elected in 2014. | Jul 16, 2013 – present | Democratic | Ed Markey | 30 |
| 28 | Elizabeth Warren | Democratic | Jan 3, 2013 – present | Re-elected in 2018. | 40 | 116th | 39 | Re-elected in 2014. | Jul 16, 2013 – present | Democratic | Ed Markey | 30 |
| 28 | Elizabeth Warren | Democratic | Jan 3, 2013 – present | Re-elected in 2018. | 40 | 117th | 40 | Re-elected in 2020. | Jul 16, 2013 – present | Democratic | Ed Markey | 30 |
| 28 | Elizabeth Warren | Democratic | Jan 3, 2013 – present | Re-elected in 2018. | 40 | 118th | 40 | Re-elected in 2020. | Jul 16, 2013 – present | Democratic | Ed Markey | 30 |
| 28 | Elizabeth Warren | Democratic | Jan 3, 2013 – present | Re-elected in 2024. | 41 | 119th | 40 | Re-elected in 2020. | Jul 16, 2013 – present | Democratic | Ed Markey | 30 |
| 28 | Elizabeth Warren | Democratic | Jan 3, 2013 – present | Re-elected in 2024. | 41 | 120th | 41 | To be determined in the 2026 election. | To be determined in the 2026 election. | To be determined in the 2026 election. | To be determined in the 2026 election. | To be determined in the 2026 election. |
| # | Senator | Party | Years in office | Electoral history | T | C | T | Electoral history | Years in office | Party | Senator | # |
| Class 1 | Class 1 | Class 1 | Class 1 | Class 1 | Class 1 | C | Class 2 | Class 2 | Class 2 | Class 2 | Class 2 | Class 2 |