OpenLLM-France/wikimedia huggingface dataset:
# RTI-31

RTI-31 ((–)-2β-carbomethoxy-3β-(4'-chlorophenyl)tropane) is a synthetic analog of cocaine that acts as a stimulant. Semi-synthesis of this compound is dependent upon the availability of cocaine starting material. According to the article, RTI-31 is 64 times the strength of cocaine in terms of its potency to elicit self-administration in monkeys. WIN 35428 was 6 times weaker than RTI-31, whereas RTI-51 was 2.6 times weaker than RTI-31.
A further advantage, in addition to potency of this compound, is that its duration of activity is longer than for cocaine. It could therefore be considered within the context as an agonist based therapy for treating cocaine addiction, although it is actually RTI-336 that entered into clinical trials with this in mind. RTI-31 is already completely psychoactive in its own right meaning that further chemical manipulation should be viewed as an option that is not strictly necessary. RTI-336 is actually made using RTI-31 as starting material. RTI-31 is not an entirely selective DRI in that it also has appreciable SERT and NET blocking affinity. RTI-31 can easily be "cleaned" though, as is done, for instance, by replacing the carbomethoxy ester with a more sterically occluded substituent such as is done for RTI-113.

## Binding and uptake selectivity

Based on the uptake of tritiated biogenic monoamine radiotracers it can be confirmed by observing the figures in the attached table that RTI-31 is a relatively balanced reuptake inhibitor wrt the D/N/S ratio.
The binding ligand affinities for the different transporters is skewed somewhat in favor of the DAT; there may be some bias in the data. The reason for this could be that WIN35428 is relatively easier to displace from the DAT versus paroxetine from the SERT, because of the higher binding constant of the former compound.
Also it needs to be borne in mind the idea of transporter promiscuity. It may be possible that the NE levels are raised, at least in part, through DAT blockade.
RTI-31 lies somewhere in the middle of the table between troparil on one end and RTI-55 on the other. It is not as selective as RTI-113 for the DAT, but is more selective than dichloropane is for this transporter. RTI-31 also has some muscarinic acetylcholine agonist activity.
MAT IC$_{50}$ (and K$_i$) for simple phenyltropanes with 1R,2S,3S stereochemistry. :
| Compound | [$^3$H]CFT | [$^3$H]DA | [$^3$H]Nisoxetine | [$^3$H]NE | [$^3$H]Paroxetine | [$^3$H]5-HT |
| Cocaine | 89.1 | 275 cf. 241 | 3300 (1990) | 119 cf. 161 | 1050 (45) | 177 cf. 112 |
| Troparil | 23 | 49.8 | 920 (550) | 37.2 | 1960 (178) | 173 |
| WIN 35428 | 13.9 | 23.0 | 835 (503) | 38.6 | 692 (63) | 101 |
| RTI-31 | 1.1 | 3.68 | 37 (22) | 5.86 | 44.5 (4.0) | 5.00 |
| RTI-113 | 1.98 | 5.25 | 2,926 | 242 | 2,340 | 391 |
| RTI-51 | 1.7 | ? | 37.4 (23) | ? | 10.6 (0.96) | ? |
| RTI-55 | 1.3 | 1.96 | 36 (22) | 7.51 | 4.21 (0.38) | 1.74 |
| RTI-32 | 1.7 | 7.02 | 60 (36) | 8.42 | 240 (23) | 19.4 |
Data in Above table from rats brains (1995). More recent work has advocated using cloned human transporters.
# Silvinho (footballer, born 1977)

Sílvio José Canuto (born 17 January 1977), commonly known as Silvinho, is a Brazilian football coach and former player who played as an attacking midfielder. He is the current head coach of Monte Azul.

## Club statistics

| Club performance | Club performance | Club performance | League | League | Cup | Cup | League Cup | League Cup | Total | Total |
| Season | Club | League | Apps | Goals | Apps | Goals | Apps | Goals | Apps | Goals |
| Japan | Japan | Japan | League | League | Emperor's Cup | Emperor's Cup | J.League Cup | J.League Cup | Total | Total |
| 2002 | Vegalta Sendai | J1 League | 27 | 2 | 2 | 0 | 6 | 0 | 35 | 2 |
| 2003 | Vegalta Sendai | J1 League | 26 | 1 | 1 | 0 | 4 | 1 | 31 | 2 |
| 2004 | Vegalta Sendai | J2 League | 35 | 5 | 2 | 1 | - | - | 37 | 6 |
| 2005 | Vegalta Sendai | J2 League | 29 | 3 | 1 | 0 | - | - | 30 | 3 |
| 2006 | Albirex Niigata | J1 League | 30 | 3 | 2 | 0 | 5 | 0 | 37 | 3 |
| 2007 | Albirex Niigata | J1 League | 22 | 1 | 1 | 0 | 5 | 0 | 28 | 1 |
| 2010 | Yokohama FC | J2 League | 11 | 0 | 0 | 0 | - | - | 11 | 0 |
| Total | Total | Total | 180 | 15 | 9 | 1 | 20 | 1 | 209 | 17 |

## Honours
### Player

Atlético Paranaense
* Campeonato Paranaense: 2000
# Rowenta

Rowenta is a German manufacturer of small household appliances. Since 1988, it has been part of the global French Groupe SEB. The German subsidiary is Rowenta Werke GmbH in Erbach in the Odenwald district in Hesse.

## History

Robert Ferdinand August Weintraud (1860–1927) founded Robert Weintraud GmbH & Co KG in 1884, and trademarked the brand name Rowenta, an amalgamation of the company's full name, in December 1909. His family lived in Offenbach am Main.
The company initially used the slogan Muss heute eine Rowenta sein (today [it] must be a Rowenta). In 2005 they introduced Intelligent Beauty. In 2014, they introduced the new slogan "Enjoy Technology"

### Product Introductions

* 1919 - an electric iron
* 1926 - the first electric coffee maker for restaurants
* 1949 - the first iron with a thermostat (with ceramic heating elements)
* 1957 - the first steam iron
* 1967 - hair drying bonnet
* 1971 - KG-22 coffee maker (Filtermatic)
* 1974 - its first vacuum cleaner
* 2001 - bagless vacuum cleaner (Infinium)

## Ownership

Rowenta was bought by the French Groupe SEB in 1988.

## Structure

The company is based in Erbach im Odenwald in Odenwaldkreis. It is located off the B43 next to the A661 bridge over the River Main, in the Gewerbegebiet Kaiserlei near the Best Western Macrander Hotel. The site is also the headquarters of Groupe SEB Deutschland.
# Portuguese Labour Party

The Portuguese Labour Party (Portuguese: Partido Trabalhista Português, PTP) is a Portuguese centre-left political party currently led by Amândio Madaleno. It was recognized by the Portuguese Constitutional Court on 1 July 2009.
It had 3 seats in the Legislative Assembly of Madeira from 2011 to 2015. In the 2015 Madeiran regional election, the party ran on an electoral list with the Socialist Party, the People–Animals–Nature and the Earth Party, in an alliance named Mudança (Change), which elected one PTP deputy.

## Election results
### Assembly of the Republic

| Election | Leader | Votes | % | Seats | +/- | Government |
| 2009 | Amândio Madaleno | 4,974 | 0.1 (#14) | 0 / 230 | | No seats |
| 2011 | Amândio Madaleno | 16,895 | 0.3 (#11) | 0 / 230 | 0 | No seats |
| 2015 | Joana Amaral Dias | AGIR! | AGIR! | 0 / 230 | 0 | No seats |
| 2019 | Amândio Madaleno | 8,299 | 0.2 (#20) | 0 / 230 | 0 | No seats |
| 2022 | Amândio Madaleno | 4,388 | 0.1 (#21) | 0 / 230 | 0 | No seats |
| 2024 | José Manuel Coelho | 2,443 | 0.0 (#18) | 0 / 230 | 0 | No seats |

### European Parliament

| Election | Leader | Votes | % | Seats | +/– | EP Group |
| 2014 | José Manuel Coelho | 22,542 | 0.7 (#10) | 0 / 21 | | – |
| 2019 | Gonçalo Madaleno | 8,640 | 0.3 (#16) | 0 / 21 | 0 | – |
| 2024 | José Manuel Coelho | 4,307 | 0.1 (#16) | 0 / 21 | 0 | – |

### Regional Assemblies
#### Madeira Regional Parliament

| Election | Leader | Votes | % | Seats | +/- | Government |
| 2011 | José Manuel Coelho | 10,115 | 6.9 (#4) | 3 / 47 | | Opposition |
| 2015 | José Manuel Coelho | Change | Change | 1 / 47 | 2 | Opposition |
| 2019 | Raquel Coelho | 1,426 | 1.0 (#10) | 0 / 47 | 1 | No seats |
| 2023 | Quintino Costa | 1,369 | 1.0 (#9) | 0 / 47 | 0 | No seats |
| 2024 | Raquel Coelho | 1,222 | 0.9 (#10) | 0 / 47 | 0 | No seats |
# Caerphilly Athletic F.C.

Caerphilly Athletic F.C. is a Welsh football club based in Caerphilly. The team currently plays in the South Wales Premier League. Until 2017, the club was called Dynamo Aber F.C.
The club have competed in the Welsh Cup, getting to the second round in 2017–18, where they lost to Penrhyncoch.

## Honours

* South Wales Alliance League Division One – Champions: 2022–23
* Taff Ely & Rhymney Valley Alliance League Premier Division – Champions: 2013–14
# Ferigolomys

Ferigolomys is an extinct genus of dinomyid rodent that inhabited Brazil during the Late Miocene. It contains a single species, F. pacarana.
# Benjamín Rivera Noriega Airport

Benjamín Rivera Noriega Airport (IATA: CPX, ICAO: TJCP, FAA LID: CPX) is a public use airport on the island of Culebra in Puerto Rico. The airport is owned by the Puerto Rico Ports Authority. It is included in the National Plan of Integrated Airport Systems for 2011–2015, which categorized it as a general aviation airport. However, the airport does offer scheduled passenger service.

## History

The airport of Culebra was originally built as a military airport by the United States Marine Corps, opening in 1957. In 1965, the government of Puerto Rico started flying civilians from San Juan to the island with a Legislative compensation.
After the Navy-Culebra protests, the Puerto Rico Ports Authority started administering the civilian flight operations in Culebra, inaugurating the first passenger terminal on October 24, 1976. The airport and its 80 acres were officially transferred to the Ports Authority in 1980.
A new passenger terminal was inaugurated in 1994, and its name was changed to Benjamín Rivera Noriega, in honor of a pilot from Ciales. He became a community leader recognized by his service to the residents of Culebra.

## Facilities and aircraft

Benjamín Rivera Noriega Airport covers an area of 15 acres (6 ha) at an elevation of 49 feet (15 m) above mean sea level. It has one runway designated 13/31 with an asphalt surface measuring 2,600 by 50 feet (792 x 15 m).
The airport is noted for the mountain less than 1,000 feet (300 m) from the north end of the runway. This obstacle and the short length of the runway keep jet aircraft from using this airport. Commercial operations are currently limited to propeller aircraft with 10 seats or less. The approach to this airport is considered good practice for pilots before flying to Saint Barthélemy Airport.
The St Thomas VOR/DME (Ident: STT) is located 16.1 nautical miles (18.5 mi) east of the airport. The Roosevelt Roads TACAN (Ident: NRR) is located 19.9 nautical miles (22.9 mi) west-southwest of the airport.

## Airlines and destinations

| Airlines | Destinations |
| Air Flamenco | Ceiba, San Juan–Isla Grande |
| Cape Air | San Juan–LMM, Vieques |
| Vieques Air Link | Ceiba, San Juan–Isla Grande, Vieques |

## Incidents

On July 1, 2011, a Cessna 185 that took off from Benjamin Rivera Noriega airport with a family of five on board, registration number N8436Q, crashed while on its way to Mercedita Airport in Ponce. One body was found in Humacao. The other four passengers are presumed dead. The plane's wreckage was found immersed in water at the Atlantic Ocean, near Yabucoa.
# List of Armenian women artists

This is a list of women artists who were born in Armenia or whose artworks are closely associated with that country.

## A

* Clara Abkar (1916–1996), Iranian-born Armenian painter and gilder
* Lusik Aguletsi (1946–2018), Soviet Armenian painter
* Maide Arel (1907–1997), Turkish-born Armenian cubist painter
* Karine Aslamazyan, painter and musician
* Eranuhi Aslamazyan (1910–1998), painter
* Mariam Aslamazyan (1907–2006), painter

## B

* Sonia Balassanian (born 1942), painter, sculptor, installation artist, curator
* Zabelle C. Boyajian (1873–1957), painter, writer
* Lavinia Bazhbeuk-Melikyan (1922–2005), Soviet-Armenian painter
* Zuleika Bazhbeuk-Melikyan (born 1939), painter
* Zabelle C. Boyajian (1873–1957), painter and writer

## C

* Tatev Chakhian (born 1992), Armenian-born Polish visual artist, poet

## D

* Nelly Danielyan (born 1978), painter

## G

* Ada Gabrielyan (born 1941), painter
* Nona Gabrielyan (born 1944), Armenian-born German sculptor and educator
* Daria Gamsaragan (1907–1986), Egyptian-born Armenian visual artist, writer
* Mari Gerekmezyan (1913–1947), Armenian-Turkish sculptor
* Regina Ghazaryan (1915–1999), painter
* Stella Grigoryan (born 1989), sculptor

## H

* Mariam Hakobyan (born 1949), sculptor

## K

* Armine Kalents (1920–2007), painter
* Jackie Kazarian, American painter, video artist, and installation artist of Armenian descent
* Noura Kevorkian, Armenian-Syrian-Lebanese writer, director, and producer
* Gayane Khachaturian (1942–2009), Georgian-Armenian painter, graphic artist

## M

* Hripsime Margaryan (born 1975), painter, sculptor
* Armenouhi Martirosyan (born 1961), painter
* Margarita Matulyan (born 1985), painter
* Tereza Mirzoyan (1922–2016), sculptor
* Varteni Mosdichian (born 1953), Boston-based Armenian artist, educator
* Alina Mnatsakanian (born 1958), Iranian-Armenian Switzerland-based visual artist

## N

* Arpenik Nalbandyan (1916–1964), Soviet-Armenian painter

## S

* Hripsime Simonyan (1916–1998), sculptor, ceramist, decorative artist
* Nune Siravyan (born 1973), illustrator, jewelry designer, theatrical costume creator
* Lilit Soghomonyan (born 1969), painter

## T

* Lilit Teryan (1930–2019), sculptor
* Arevik Tserunyan (born 1987), painter and draftperson
* Armine Tumanyan (born 1975), painter
* Nune Tumanyan (born 1963), sculptor, educator

## U

* Aytsemnik Urartu (1899–1974), sculptor

## V

* Knarik Vardanyan (1914–1996), Armenian Soviet painter and printmaker
# Joel Funk Asper

Joel Funk Asper (April 20, 1822 – October 1, 1872) was a U.S. Representative from Missouri.

## Early life and education

Born in Adams County, Pennsylvania, Asper moved to Ohio with his parents, who settled in Trumbull County in 1827. He attended the public schools and the local college in Warren, Ohio. He studied law. He was admitted to the bar in 1844 and commenced practice in Warren, Ohio.

## Early career

He served as a Justice of the Peace in 1846. He served as prosecuting attorney of Geauga County in 1847. Asper served as a delegate to the Buffalo Free-Soil Convention in 1848. He was editor of the Western Reserve Chronicle in 1849. He moved to Iowa in 1850 and published the Chardon Democrat.

## Civil War service

Asper raised a company for the Civil War in 1861 and served as its captain. He was wounded in the Battle of Winchester.
He was promoted to the rank of lieutenant colonel in 1862. He mustered out of the service in 1863, because of wounds received in action.
He became the Colonel of the 171st Ohio (a One Hundred Day Regiment) in May 1864 to August 1864. He served at the Prisoner of War Camp at Johnson's Island, Ohio. He was forced to surrender to John Hunt Morgan seven of the regiment's companies at Keller's Bridge, Kentucky, on June 12, 1864. The units were illegally paroled. Asper and the regiment returned to Johnson's Island. He mustered out at end of term of service.

## Other pursuits

He moved to Chillicothe, Missouri, in 1864 and resumed the practice of law in partnership with Henry M. Pollard. He founded the Spectator in 1866. He served as delegate to the Republican National Convention in 1868.

## Congress

Asper was elected as a Republican to the Forty-first Congress (March 4, 1869 – March 3, 1871). He was not a candidate for renomination in 1870.

## Death and legacy

Asper practiced law until his death. He died in Chillicothe, Missouri, on October 1, 1872. He was interred in Edgewood Cemetery.
# Ebinho

José Edipo Deodato dos Santos or Ebinho for short (born 18 January 1988) is a Brazilian professional footballer, who plays as a fast and header forward. He is currently in Associação Cultural e Desportiva Potiguar.
Ebinho joined Portuguese side Marítimo in 2014, but he struggled to adapt to playing as a striker only scoring twice during his first season.
# Ella Watson

Ella Watson (March 27/29, 1883 – April 3, 1980) was an American janitor and charwoman who was famously the subject of Gordon Parks' photographic series including American Gothic in 1942, among at least 90 other photographs. According to the Gordon Parks Foundation, "Parks asked if he could take Watson’s picture. She agreed, and for four months gave him access to her home and her community. The resulting photographs were a breakthrough in Parks’ career." In 2024, the Minneapolis Institute of Art exhibited 60 of the photographs.

## Early life and career

Ella Watson was born in Washington D.C., United States on either March 27 or March 29, 1883. She left school when she was 15, which is also when she began work as an ironer at Frazee Laundry in Washington. Until 1919, census records show she worked intermittently as a maid and laundress, after which she was employed as a janitor by the United States Department of State, later a caretaker at a family's home, a different federal agency building, the Post Office Department, and then the Department of the Treasury in 1929, where she worked until 1944. In Parks' memoir A Hungry Heart, by the time he met her in 1942, Watson's father was lynched, her husband shot to death in 1927, her daughter died after bearing two illegitimate children. At the time, she was living in an apartment and was raising her adopted daughter and grandchildren as a single parent.

## American Gothic

Gordon Parks was an American photographer who, through a fellowship from the Rosenwald Fund, arrived in Washington D.C. in January 1942, where he gained employment at the Historical Section of the Farm Security Administration.

## Legacy

Historican Deborah Willies interviewed her grandchildren in 2018. The book American Gothic; Gordon Parks and Ella Watson published in 2024 explores the series of photographs and the historic collaboration between photographer and subject. The Library of Congress has a collection of the images. Watson is identified as a charwoman in the photos.
# Isaac Ruzama Jimba

Isaac Ruzama Jimba is a Nigerian politician from Kogi State, born in October 1948. He served as a member of the National Assembly, representing the Bassa/Dekina Federal Constituency from 1990 to 2003 and again in 2003 to 2007, as a member of the All Nigeria Peoples Party (ANPP).
# Clemens Voorhoeve

Clemens Lambertus Voorhoeve (born 1930; also known as "Bert" Voorhoeve) is a Dutch linguist who specializes in Papuan languages.

## Education

He completed his higher education in the Netherlands. He obtained his PhD in linguistics at Leiden University. Prior to obtaining his doctorate, he conducted fieldwork in among the Asmat people of Papua.

## Career

In 1965, he was employed as a researcher at the Australian National University.
He conducted extensive linguistic research in western and southern Papua New Guinea, as well as in Western New Guinea. He has also contributed significantly to the classifications of Papuan languages.
Voorhoeve retired in 1988.

## Selected publications

* Voorhoeve, C.L. "Miscellaneous Notes on Languages in West Irian, New Guinea". In Dutton, T., Voorhoeve, C. and Wurm, S.A. editors, Papers in New Guinea Linguistics No. 14. A-28:47-114. Pacific Linguistics, The Australian National University, 1971. doi:10.15144/PL-A28.47
* Voorhoeve, C.L. Languages of Irian Jaya: Checklist. Preliminary classification, language maps, wordlists. B-31, iv + 133 pages. Pacific Linguistics, The Australian National University, 1975. doi:10.15144/PL-B31
* Voorhoeve, C.L. "The Languages of the Lake Murray Area". In Voorhoeve, C., McElhanon, K., Blowers, B. and Blowers, R. editors, Papers in New Guinea Linguistics No. 12. A-25:1-18. Pacific Linguistics, The Australian National University, 1970. doi:10.15144/PL-A25.1
* Voorhoeve, C.L. The Asmat languages of Irian Jaya. B-64, x + 187 pages. Pacific Linguistics, The Australian National University, 1980. doi:10.15144/PL-B64
* Voorhoeve, C.L. editor. The Makian languages and their neighbours. D-46, viii + 156 pages. Pacific Linguistics, The Australian National University, 1982. doi:10.15144/PL-D46
* McElhanon, K.A. and Voorhoeve, C.L. The Trans-New Guinea Phylum: Explorations in deep-level genetic relationships. B-16, vi + 112 pages. Pacific Linguistics, The Australian National University, 1970. doi:10.15144/PL-B16
# Milward Adams

Milward Adams (January 6, 1857 – June 18, 1923) was born in Lexington, Kentucky.
Adams rose to prominence as the first manager of the Chicago Symphony Orchestra and the Auditorium Theatre. Adams worked his way up in the performing arts world, beginning as a janitor at various theaters and ending as a theater manager with many connections in the Chicago arts scene.
He managed the great May musical festivals of 1882 and 1884; also summer night concerts under the direction of Theodore Thomas for ten years.
He died at the Auditorium Hotel on June 18, 1923.
# Christopher S. Carpenter

Christopher S. "Kitt" Carpenter is an American economist who is E. Bronson Ingram Chair and Professor of Economics at Vanderbilt University, founder and director of the Vanderbilt LGBT Policy Lab and director of the Vanderbilt Program in Public Policy Studies. He is also Director of the National Bureau of Economic Research Health Economics program, Editor of the Journal of Health Economics, President-elect of the Association for Public Policy Analysis and Management, and co-founder and co-chair of the American Economic Association Committee on the Status of LGBTQ+ Individuals in the Economics Profession.
In 2023, he was the first recipient of the Distinguished Service Award from the American Economic Association, awarded "for his selfless and persistent efforts to foster a welcoming environment for all economists and others aspiring to join our ranks."

## Education and early life

Carpenter is "a first-generation college graduate, a Korean adoptee, and a gay person." He graduated from Albion College in 1997 with a degree in Economics, Math, and Public Service and completed a doctorate in economics at the University of California at Berkeley in 2002.

## Career

Carpenter was a Robert Wood Johnson Foundation Postdoctoral Scholar in Health Policy Research from 2002 to 2004, when he joined the faculty of the Paul Merage School of Business at the University of California at Irvine. In 2013, he became a professor of Economics at Vanderbilt University.

### Research

Much of Carpenter's research focuses on the intersection of public policies (such as underage drunk driving laws, minimum drinking ages, and alcohol sales restrictions) with health behaviors, such as alcohol consumption and seat-belt usage. He has also written extensively on economic disparities by sexual orientation and on the economic impact of legal same-sex marriage.

#### Selected works

* Davis, Brennan, and Christopher Carpenter. "Proximity of fast-food restaurants to schools and adolescent obesity." American journal of public health 99, no. 3 (2009): 505–510.
* Carpenter, Christopher, and Carlos Dobkin. "The effect of alcohol consumption on mortality: regression discontinuity evidence from the minimum drinking age." American Economic Journal: Applied Economics 1, no. 1 (2009): 164–182.
* Carpenter, Christopher, and Philip J. Cook. "Cigarette taxes and youth smoking: new evidence from national, state, and local Youth Risk Behavior Surveys." Journal of health economics 27, no. 2 (2008): 287–299.
* Carpenter, Christopher S. "Self-reported sexual orientation and earnings: Evidence from California." ILR Review 58, no. 2 (2005): 258–273.
* Carpenter, Christopher, and Carlos Dobkin. "The minimum legal drinking age and public health." Journal of Economic Perspectives 25, no. 2 (2011): 133–156.