# List of Major League Soccer transfers 2021

The following is a list of transfers for the 2021 Major League Soccer (MLS) season that have been made during the 2020–21 MLS offseason all the way through to the roster freeze.

## Transfers

List of 2021 MLS transfers :
| Date | Name | Moving from | Moving to | Mode of Transfer |
| November 13, 2020 | Chinonso Offor | FK RFS | Chicago Fire | Transfer |
| November 19, 2020 | Andres Jasson | Yale Bulldogs | New York City FC | Homegrown player |
| November 19, 2020 | Cameron Lancaster | Nashville SC | Louisville City | Transfer |
| November 23, 2020 | Jhon Espinoza | S.D. Aucas | Chicago Fire | Transfer |
| November 25, 2020 | Pablo Aránguiz | FC Dallas | Universidad de Chile | Transfer |
| November 25, 2020 | Jacob Greene | Loudoun United | D.C. United | Homegrown player |
| December 1, 2020 | Zorhan Bassong | Cercle Brugge | CF Montréal | Free |
| December 1, 2020 | Antônio Carlos | Palmeiras | Orlando City SC | Transfer |
| December 1, 2020 | Ariel Lassiter | Alajuelense | Houston Dynamo | Transfer |
| December 2, 2020 | Alexander Alvarado | S.D. Aucas | Orlando City SC | Transfer |
| December 2, 2020 | Andrés Perea | Atlético Nacional | Orlando City SC | Transfer |
| December 2, 2020 | Rodrigo Schlegel | Racing Club | Orlando City SC | Transfer |
| December 3, 2020 | Jackson Conway | Atlanta United 2 | Atlanta United FC | Homegrown player |
| December 4, 2020 | Jean-Aniel Assi | Montreal Impact Academy | CF Montréal | Homegrown player |
| December 4, 2020 | Siem de Jong | FC Cincinnati | SC Heerenveen | Free |
| December 4, 2020 | Sean Rea | Montreal Impact Academy | CF Montréal | Homegrown player |
| December 4, 2020 | Nathan-Dylan Saliba | Montreal Impact Academy | CF Montréal | Homegrown player |
| December 4, 2020 | Rida Zouhir | Montreal Impact Academy | CF Montréal | Homegrown player |
| December 7, 2020 | Evan Newton | Indy Eleven | New York City FC | Loan |
| December 8, 2020 | Mathias Jørgensen | New York Red Bulls | AGF | Loan |
| December 8, 2020 | Mauro Manotas | Houston Dynamo | Club Tijuana | Transfer |
| December 9, 2020 | Stanislav Ivanov | Levski Sofia | Chicago Fire | Transfer |
| December 11, 2020 | Luca Lewis | New York Red Bulls II | New York Red Bulls | Free |
| December 13, 2020 | Evan Bush | Vancouver Whitecaps FC | Columbus Crew | Trade |
| December 13, 2020 | Julio Cascante | Portland Timbers | Austin FC | Trade |
| December 13, 2020 | Marco Farfan | Portland Timbers | Los Angeles FC | Trade |
| December 13, 2020 | Jon Gallagher | Atlanta United FC | Austin FC | Trade |
| December 13, 2020 | Nick Lima | San Jose Earthquakes | Austin FC | Trade |
| December 13, 2020 | Callum Montgomery | FC Dallas | Minnesota United FC | Trade |
| December 13, 2020 | Ulises Segura | D.C. United | Austin FC | Trade |
| December 13, 2020 | Ben Sweat | Inter Miami CF | Austin FC | Trade |
| December 16, 2020 | Joe Corona | LA Galaxy | Austin FC | Expansion Draft |
| December 16, 2020 | Danny Hoesen | San Jose Earthquakes | Austin FC | Expansion Draft |
| December 16, 2020 | Kamal Miller | Orlando City SC | Austin FC | Expansion Draft |
| December 16, 2020 | Kamal Miller | Austin FC | CF Montréal | Trade |
| December 16, 2020 | Brady Scott | Nashville SC | Austin FC | Expansion Draft |
| December 16, 2020 | Jared Stroud | New York Red Bulls | Austin FC | Expansion Draft |
| December 17, 2020 | Claudio Bravo | Banfield | Portland Timbers | Transfer |
| December 17, 2020 | Raheem Edwards | Minnesota United FC | Los Angeles FC | Re-Entry Draft |
| December 17, 2020 | Andrew Gutman | FC Cincinnati | Atlanta United FC | Re-Entry Draft |
| December 17, 2020 | Kendall McIntosh | New York Red Bulls | Sporting Kansas City | Re-Entry Draft |
| December 17, 2020 | Djordje Mihailovic | Chicago Fire | CF Montréal | Trade |
| December 17, 2020 | Fafà Picault | FC Dallas | Houston Dynamo | Trade |
| December 17, 2020 | Alexander Ring | New York City FC | Austin FC | Trade |
| December 18, 2020 | Brandt Bronico | Chicago Fire | Charlotte FC | Trade |
| December 18, 2020 | Felipe Valencia | Inter Miami Academy | Inter Miami CF | Homegrown player |
| December 19, 2020 | Earl Edwards Jr. | D.C. United | New England Revolution | Free |
| December 21, 2020 | Hector Jiménez | Columbus Crew | Austin FC | Free |
| December 21, 2020 | Christian Mafla | Atlético Nacional | New England Revolution | Transfer |
| December 21, 2020 | José Martínez | SD Eibar | FC Dallas | Transfer |
| December 22, 2020 | Mikey Ambrose | Inter Miami CF | Atlanta United FC | Free |
| December 22, 2020 | Joe Corona | Austin FC | Houston Dynamo | Re-Entry Draft |
| December 22, 2020 | Eric Dick | Sporting Kansas City | Columbus Crew | Re-Entry Draft |
| December 22, 2020 | Jáder Obrian | Rionegro Águilas | FC Dallas | Transfer |
| December 22, 2020 | Adrien Perez | Los Angeles FC | D.C. United | Re-Entry Draft |
| December 22, 2020 | Jhohan Romaña | Guaraní | Austin FC | Transfer |
| December 22, 2020 | Rémi Walter | Yeni Malatyaspor | Sporting Kansas City | Free |
| December 23, 2020 | Rolf Feltscher | LA Galaxy | Würzburger Kickers | Free |
| December 23, 2020 | Wilfrid Kaptoum | Real Betis | New England Revolution | Free |
| December 23, 2020 | Patrick Seagrist | New York Red Bulls | Inter Miami CF | Trade |
| December 23, 2020 | Andrew Tarbell | Columbus Crew | Austin FC | Free |
| December 23, 2020 | Bradley Wright-Phillips | Los Angeles FC | Columbus Crew | Free |
| December 26, 2020 | Lee Nguyen | New England Revolution | Ho Chi Minh City FC | Free |
| December 28, 2020 | Brad Stuver | New York City FC | Austin FC | Free |
| December 29, 2020 | Rónald Matarrita | New York City FC | FC Cincinnati | Trade |
| December 30, 2020 | Cody Cropper | Houston Dynamo | FC Cincinnati | Free |
| December 30, 2020 | Ben Mines | New York Red Bulls | FC Cincinnati | Waiver Draft |
| January 1, 2021 | Brenden Aaronson | Philadelphia Union | Red Bull Salzburg | Transfer |
| January 1, 2021 | Erik López | Olimpia | Atlanta United FC | Transfer |
| January 1, 2021 | Efrain Morales | Atlanta United 2 | Atlanta United FC | Homegrown player |
| January 1, 2021 | Joseph Scally | New York City FC | Borussia Mönchengladbach | Transfer |
| January 4, 2021 | Shamit Shome | CF Montréal | FC Edmonton | Free |
| January 5, 2021 | Diego Fagúndez | New England Revolution | Austin FC | Free |
| January 5, 2021 | Wil Trapp | Inter Miami CF | Minnesota United FC | Free |
| January 6, 2021 | Matt Besler | Sporting Kansas City | Austin FC | Free |
| January 6, 2021 | Santiago Patiño | Orlando City SC | San Antonio FC | Free |
| January 7, 2021 | Emmanuel Boateng | Columbus Crew | New England Revolution | Free |
| January 7, 2021 | A. J. DeLaGarza | Inter Miami CF | New England Revolution | Free |
| January 7, 2021 | Mark McKenzie | Philadelphia Union | Genk | Transfer |
| January 7, 2021 | Kevin Molino | Minnesota United FC | Columbus Crew | Free |
| January 7, 2021 | Rubio Rubin | San Diego Loyal | Real Salt Lake | Free |
| January 7, 2021 | Jørgen Skjelvik | LA Galaxy | OB | Transfer |
| January 8, 2021 | Jon Kempin | Columbus Crew | D.C. United | Trade |
| January 9, 2021 | Kyle Adams | Houston Dynamo | Real Monarchs | Free |
| January 9, 2021 | Gary Mackay-Steven | New York City FC | Heart of Midlothian | Free |
| January 11, 2021 | Corey Baird | Real Salt Lake | Los Angeles FC | Trade |
| January 11, 2021 | Jhon Durán | Envigado | Chicago Fire | Free |
| January 11, 2021 | Kim Moon-hwan | Busan IPark | Los Angeles FC | Transfer |
| January 11, 2021 | Isaiah Parente | Wake Forest Demon Deacons | Columbus Crew | Homegrown player |
| January 12, 2021 | Jeff Dewsnup | Real Salt Lake Academy | Real Salt Lake | Homegrown player |
| January 12, 2021 | Sunusi Ibrahim | 36 Lion FC | CF Montréal | Transfer |
| January 12, 2021 | Jorge Villafaña | Portland Timbers | LA Galaxy | Trade |
| January 13, 2021 | Michael Barrios | FC Dallas | Colorado Rapids | Trade |
| January 13, 2021 | January 14, 2021 | Jonathan Bond | West Bromwich Albion | LA Galaxy | Transfer |
| Kalil ElMedkhar | January 14, 2021 | Philadelphia Union | FC Dallas | Homegrown player |
| Jerome Kiesewetter | January 14, 2021 | Inter Miami CF | FC Tulsa | Free |
| Chris Lema | January 14, 2021 | New York Red Bulls | San Antonio FC | Free |
| Tyler Pasher | January 14, 2021 | Indy Eleven | Houston Dynamo | Transfer |
| Deklan Wynne | January 14, 2021 | Colorado Rapids | Phoenix Rising | Free |
| January 15, 2021 | Chris Cadden | Columbus Crew | Hibernian | Transfer |
| January 15, 2021 | Justin Dhillon | Seattle Sounders FC | San Antonio FC | Free |
| January 15, 2021 | Freddy Vargas | Deportivo Lara | FC Dallas | Loan |
| January 15, 2021 | Kendall Waston | FC Cincinnati | Saprissa | Free |
| January 18, 2021 | Aljaž Struna | Houston Dynamo | CF Montréal | Trade |
| January 18, 2021 | Maximiliano Urruti | CF Montréal | Houston Dynamo | Trade |
| January 19, 2021 | Machop Chol | Wake Forest Demon Deacons | Atlanta United FC | Homegrown player |
| January 19, 2021 | Felipe Mora | UNAM | Portland Timbers | Transfer |
| January 19, 2021 | Tim Parker | New York Red Bulls | Houston Dynamo | Trade |
| January 19, 2021 | Andrés Reyes | Atlético Nacional | New York Red Bulls | Transfer |
| January 19, 2021 | Adam Saldana | LA Galaxy II | LA Galaxy | Homegrown player |
| January 20, 2021 | Grayson Barber | Clemson Tigers | Sporting Kansas City | Homegrown player |
| January 20, 2021 | Ozzie Cisneros | Sporting Kansas City Academy | Sporting Kansas City | Homegrown player |
| January 20, 2021 | Javier López | Guadalajara | San Jose Earthquakes | Loan |
| January 20, 2021 | Jalen Neal | LA Galaxy II | LA Galaxy | Homegrown player |
| January 20, 2021 | Brooks Thompson | Sporting Kansas City II | Sporting Kansas City | Homegrown player |
| January 20, 2021 | Andrew Wooten | Philadelphia Union | Admira Wacher | Free |
| January 21, 2021 | Ethan Bartlow | Washington Huskies | Houston Dynamo | SuperDraft |
| January 21, 2021 | Bret Halsey | Virginia Cavaliers | Real Salt Lake | SuperDraft |
| January 21, 2021 | Calvin Harris | Wake Forest Demon Deacons | FC Cincinnati | SuperDraft |
| January 21, 2021 | Derrick Jones | Nashville SC | Houston Dynamo | Trade |
| January 21, 2021 | Philip Mayaka | Clemson Tigers | Colorado Rapids | SuperDraft |
| January 21, 2021 | João Paulo | Botafogo | Seattle Sounders FC | Transfer |
| January 21, 2021 | Daniel Pereira | Virginia Tech Hokies | Austin FC | SuperDraft |
| January 22, 2021 | Brandon Austin | Tottenham Hotspur Under-23 | Orlando City SC | Loan |
| January 22, 2021 | Marcus Ferkranus | LA Galaxy II | LA Galaxy | Homegrown player |
| January 22, 2021 | Kekuta Manneh | New England Revolution | Austin FC | Free |
| January 22, 2021 | Jordan Morris | Seattle Sounders FC | Swansea City | Loan |
| January 22, 2021 | Jesús David Murillo | Independiente Medellín | Los Angeles FC | Transfer |
| January 22, 2021 | Miguel Nazarit | Nashville SC | Santa Fe | Loan |
| January 24, 2021 | Abdul Rwatubyaye | Colorado Rapids | KF Shkupi | Free |
| January 24, 2021 | Román Torres | Seattle Sounders FC | Cartaginés | Free |
| January 25, 2021 | Wikelman Carmona | Dynamo Margarita | New York Red Bulls | Transfer |
| January 25, 2021 | Lisandro López | Racing Club | Atlanta United FC | Free |
| January 26, 2021 | Edison Azcona | Fort Lauderdale CF | Inter Miami CF | Homegrown player |
| January 26, 2021 | Déiber Caicedo | Deportivo Cali | Vancouver Whitecaps FC | Transfer |
| January 26, 2021 | Ian Fray | Fort Lauderdale CF | Inter Miami CF | Homegrown player |
| January 26, 2021 | Youness Mokhtar | Columbus Crew | ADO Den Haag | Free |
| January 26, 2021 | Alvas Powell | Inter Miami CF | Al-Hilal | Free |
| January 27, 2021 | Jeff Caldwell | New England Revolution | Hartford Athletic | Free |
| January 27, 2021 | Dylan Castanheira | Fort Lauderdale CF | Inter Miami CF | Free |
| January 27, 2021 | Tom Edwards | Stoke City | New York Red Bulls | Loan |
| January 27, 2021 | Kyle Morton | Saint Louis FC | Houston Dynamo | Free |
| January 28, 2021 | David Accam | Nashville SC | Hammarby IF | Loan |
| January 28, 2021 | Andrew Booth | Minnesota United FC | CF Montréal | Trade |
| January 28, 2021 | Josué Colmán | Orlando City SC | Guaraní | Free |
| January 28, 2021 | Antonio Delamea | New England Revolution | Olimpija Ljubljana | Free |
| January 28, 2021 | Perry Kitchen | LA Galaxy | Columbus Crew | Free |
| January 28, 2021 | Jukka Raitala | CF Montréal | Minnesota United FC | Trade |
| January 29, 2021 | Luis Felipe | San Jose Earthquakes | Sacramento Republic | Free |
| January 29, 2021 | Evan Newton | Indy Eleven | Vancouver Whitecaps FC | Transfer |
| January 29, 2021 | Kelyn Rowe | New England Revolution | Seattle Sounders FC | Free |
| January 30, 2021 | Tomás Martínez | Houston Dynamo | Defensa y Justicia | Free |
| February 1, 2021 | Paul Arriola | D.C. United | Swansea City | Loan |
| February 1, 2021 | Micheal Azira | Chicago Fire | New Mexico United | Free |
| February 1, 2021 | Daryl Dike | Orlando City SC | Barnsley | Loan |
| February 1, 2021 | David Egbo | Akron Zips | Vancouver Whitecaps FC | SuperDraft |
| February 1, 2021 | Bryan Reynolds | FC Dallas | Roma | Loan |
| February 1, 2021 | Robinho | Orlando City SC | Confiança | Free |
| February 1, 2021 | Brian Rodríguez | Los Angeles FC | Almería | Loan |
| February 1, 2021 | Tomas Romero | Philadelphia Union | Los Angeles FC | Homegrown player |
| February 2, 2021 | Spencer Richey | FC Cincinnati | Seattle Sounders FC | Free |
| February 2, 2021 | William Yarbrough | León | Colorado Rapids | Transfer |
| February 3, 2021 | Keesean Ferdinand | CF Montréal | Atlético Ottawa | Loan |
| February 3, 2021 | Nicolas Isimat-Mirin | Beşiktaş | Sporting Kansas City | Free |
| February 3, 2021 | Bjørn Johnsen | Ulsan Hyundai | CF Montréal | Transfer |
| February 3, 2021 | Rodrigo Piñeiro | Danubio | Nashville SC | Transfer |
| February 3, 2021 | Jonathan Suárez | Querétaro | Orlando City SC | Loan |
| February 3, 2021 | Josecarlos Van Rankin | Guadalajara | Portland Timbers | Loan |
| February 3, 2021 | Karifa Yao | CF Montréal | Cavalry FC | Loan |
| February 4, 2021 | Jorge Corrales | CF Montréal | FC Tulsa | Free |
| February 4, 2021 | Ahmed Hamdy | El Gouna | CF Montréal | Loan |
| February 4, 2021 | Aaron Schoenfeld | Minnesota United FC | Austin FC | Free |
| February 4, 2021 | Joaquín Torres | Newell's Old Boys | CF Montréal | Loan |
| February 5, 2021 | Brenner | São Paulo | FC Cincinnati | Transfer |
| February 5, 2021 | Michael DeShields | Wake Forest Demon Deacons | D.C. United | SuperDraft |
| February 5, 2021 | Fábio | Oeste | New York Red Bulls | Loan |
| February 9, 2021 | Alex DeJohn | Orlando City SC | Pittsburgh Riverhounds | Free |
| February 9, 2021 | Franco Escobar | Atlanta United FC | Newell's Old Boys | Loan |
| February 9, 2021 | Bento Estrela | New York Red Bulls Academy | New York Red Bulls | Homegrown player |
| February 9, 2021 | Freddy Kleemann | Washington Huskies | Austin FC | SuperDraft |
| February 9, 2021 | Brandon Servania | FC Dallas | SKN St. Pölten | Loan |
| February 10, 2021 | Michael Mancienne | New England Revolution | Burton Albion | Free |
| February 10, 2021 | Tommy McCabe | FC Cincinnati | Orange County SC | Free |
| February 10, 2021 | C. J. Sapong | Chicago Fire | Nashville SC | Free |
| February 11, 2021 | Tomás Pochettino | Talleres | Austin FC | Transfer |
| February 12, 2021 | Malte Amundsen | Vejle BK | New York City FC | Transfer |
| February 12, 2021 | Justin Che | FC Dallas | Bayern Munich II | Loan |
| February 12, 2021 | Tomas Giraldo | CF Montréal | FC Edmonton | Loan |
| February 12, 2021 | Josh Penn | Indiana Hoosiers | Inter Miami CF | SuperDraft |
| February 12, 2021 | Santiago Sosa | River Plate | Atlanta United FC | Transfer |
| February 13, 2021 | Alexandre Pato | São Paulo | Orlando City SC | Free |
| February 15, 2021 | Oniel Fisher | D.C. United | LA Galaxy | Free |
| February 15, 2021 | Eric Remedi | Atlanta United FC | San Jose Earthquakes | Trade |
| February 16, 2021 | Erik Hurtado | Sporting Kansas City | CF Montréal | Free |
| February 16, 2021 | Emiliano Insúa | LA Galaxy | Aldosivi | Free |
| February 16, 2021 | Benji Kikanovic | Reno 1868 | San Jose Earthquakes | Free |
| February 16, 2021 | Gerso Fernandes | Sporting Kansas City | Jeju United | Free |
| February 16, 2021 | Valeri Qazaishvili | San Jose Earthquakes | Ulsan Hyundai | Free |
| February 16, 2021 | Jan Sobociński | ŁKS Łódź | Charlotte FC | Transfer |
| February 16, 2021 | D.J. Taylor | North Carolina FC | Minnesota United FC | Free |
| February 17, 2021 | Luciano Abecasis | Libertad | San Jose Earthquakes | Transfer |
| February 17, 2021 | Javain Brown | South Florida Bulls | Vancouver Whitecaps FC | SuperDraft |
| February 17, 2021 | Robert Castellanos | Rio Grande Valley FC Toros | Nashville SC | Free |
| February 17, 2021 | Carlos Harvey | Tauro F.C. | LA Galaxy | Transfer |
| February 18, 2021 | Ronald Hernández | Aberdeen | Atlanta United FC | Loan |
| February 18, 2021 | Fernando Meza | Atlanta United FC | Defensa y Justicia | Loan |
| February 20, 2021 | Ryan Shawcross | Stoke City | Inter Miami CF | Transfer |
| February 22, 2021 | Nick Hinds | Seattle Sounders FC | Nashville SC | Trade |
| February 22, 2021 | Franco Ibarra | Argentinos Juniors | Atlanta United FC | Transfer |
| February 22, 2021 | Adam Jahn | Atlanta United FC | Orange County SC | Loan |
| February 23, 2021 | Silvester van der Water | Heracles Almelo | Orlando City SC | Transfer |
| February 24, 2021 | Gregore | Bahia | Inter Miami CF | Transfer |
| February 24, 2021 | Erik McCue | Houston Dynamo | Charleston Battery | Loan |
| February 24, 2021 | Bryan Meredith | Vancouver Whitecaps FC | Nashville SC | Free |
| February 25, 2021 | Stuart Findlay | Kilmarnock | Philadelphia Union | Transfer |
| February 25, 2021 | Gelmin Rivas | D.C. United | Al-Shorta SC | Free |
| February 25, 2021 | Reto Ziegler | FC Dallas | FC Lugano | Free |
| February 26, 2021 | Carlos Miguel Coronel | Red Bull Salzburg | New York Red Bulls | Loan |
| March 1, 2021 | Youba Diarra | Red Bull Salzburg | New York Red Bulls | Loan |
| March 1, 2021 | Jordan Hamilton | Columbus Crew | Indy Eleven | Free |
| March 1, 2021 | Wan Kuzain | Sporting Kansas City | Rio Grande Valley FC Toros | Free |
| March 2, 2021 | Juan Agudelo | Inter Miami CF | Minnesota United FC | Free |
| March 2, 2021 | David Norman Jr. | Inter Miami CF | Cavalry FC | Free |
| March 3, 2021 | Sebastian Berhalter | Columbus Crew | Austin FC | Loan |
| March 3, 2021 | Marlon Hairston | Minnesota United FC | Columbus Crew | Free |
| March 3, 2021 | Guram Kashia | San Jose Earthquakes | Locomotive Tbilisi | Free |
| March 3, 2021 | Žan Kolmanič | Maribor | Austin FC | Loan |
| March 3, 2021 | Oliver Larraz | Colorado Rapids Academy | Colorado Rapids | Homegrown player |
| March 3, 2021 | Marcelo Palomino | Houston Dynamo | Charlotte Independence | Loan |
| March 3, 2021 | Darren Yapi | Colorado Rapids Academy | Colorado Rapids | Homegrown player |
| March 4, 2021 | Michael Edwards | VfL Wolfsburg II | Colorado Rapids | Homegrown player |
| March 4, 2021 | Ben Lundgaard | Atlanta United 2 | Atlanta United FC | Free |
| March 4, 2021 | Cody Mizell | New Mexico United | New York City FC | Transfer |
| March 4, 2021 | Fredy Montero | Vancouver Whitecaps FC | Seattle Sounders FC | Free |
| March 4, 2021 | Dantouma Toure | New York Red Bulls II | Colorado Rapids | Homegrown player |
| March 4, 2021 | Patrick Weah | Minnesota United Academy | Minnesota United FC | Homegrown player |
| March 4, 2021 | Derrick Williams | Blackburn Rovers | LA Galaxy | Transfer |
| March 5, 2021 | Cameron Harper | Celtic | New York Red Bulls | Transfer |
| March 5, 2021 | Edward Kizza | Pittsburgh Panthers | New England Revolution | SuperDraft |
| March 5, 2021 | James Musa | Minnesota United FC | Phoenix Rising | Free |
| March 6, 2021 | Pablo Piatti | Toronto FC | Elche | Free |
| March 8, 2021 | Brendan Hines-Ike | KV Kortrijk | D.C. United | Loan |
| March 8, 2021 | Alexandru Mățan | Viitorul Constanța | Columbus Crew | Transfer |
| March 8, 2021 | Kimarni Smith | Clemson Tigers | D.C. United | SuperDraft |
| March 8, 2021 | Juan Pablo Torres | New York City FC | Austin Bold FC | Loan |
| March 9, 2021 | Jovanny Bolívar | Deportivo La Guaira | D.C. United | Loan |
| March 9, 2021 | Bruno Gaspar | Sporting CP | Vancouver Whitecaps FC | Loan |
| March 9, 2021 | Andrew Gutman | Atlanta United FC | New York Red Bulls | Loan |
| March 9, 2021 | Cal Jennings | Indy Eleven | Los Angeles FC | Transfer |
| March 10, 2021 | Luciano Acosta | Atlas | FC Cincinnati | Transfer |
| March 11, 2021 | Samuel Grandsir | Monaco | LA Galaxy | Transfer |
| March 11, 2021 | Joevin Jones | Seattle Sounders FC | Inter Miami CF | Free |
| March 12, 2021 | Caio Alexandre | Botafogo | Vancouver Whitecaps FC | Transfer |
| March 12, 2021 | Alex DeJohn | Pittsburgh Riverhounds | Atlanta United FC | Free |
| March 12, 2021 | Anderson Julio | Atlético San Luis | Real Salt Lake | Loan |
| March 16, 2021 | Arnór Ingvi Traustason | Malmö | New England Revolution | Transfer |
| March 17, 2021 | Víctor Vázquez | Eupen | LA Galaxy | Free |
| March 18, 2021 | Niko Hansen | Houston Dynamo | Minnesota United FC | Trade |
| March 19, 2021 | Felipe Gutiérrez | Sporting Kansas City | Universidad Católica | Free |
| March 22, 2021 | Jon Bell | New England Revolution II | New England Revolution | Free |
| March 22, 2021 | Chris Gloster | Jong PSV | New York City FC | Free |
| March 22, 2021 | Maciel | New England Revolution II | New England Revolution | Free |
| March 22, 2021 | Wilfredo Rivera | Orlando City B | Orlando City SC | Homegrown player |
| March 23, 2021 | Nicky Hernandez | SMU Mustangs | FC Dallas | SuperDraft |
| March 23, 2021 | Kelvin Leerdam | Seattle Sounders FC | Inter Miami CF | Free |
| March 23, 2021 | Nigel Robertha | Levski Sofia | D.C. United | Transfer |
| March 24, 2021 | Fatai Alashe | Columbus Crew | Sacramento Republic | Free |
| March 24, 2021 | Jeremy Kelly | Colorado Rapids | Phoenix Rising | Loan |
| March 24, 2021 | Andre Rawls | Colorado Rapids | Phoenix Rising | Loan |
| March 26, 2021 | Jasser Khmiri | Vancouver Whitecaps FC | San Antonio FC | Loan |
| March 29, 2021 | Sebastian Anderson | Colorado Rapids | Colorado Springs Switchbacks | Loan |
| March 29, 2021 | Michael Edwards | Colorado Rapids | Colorado Springs Switchbacks | Loan |
| March 29, 2021 | Matt Hundley | Colorado Rapids | Colorado Springs Switchbacks | Loan |
| March 29, 2021 | Philip Mayaka | Colorado Rapids | Colorado Springs Switchbacks | Loan |
| March 29, 2021 | Abraham Rodriguez | Colorado Rapids | Colorado Springs Switchbacks | Loan |
| March 31, 2021 | Isaac Atanga | Nordsjælland | FC Cincinnati | Transfer |
| March 31, 2021 | Leon Flach | FC St. Pauli | Philadelphia Union | Transfer |
| March 31, 2021 | Laurence Wyke | Atlanta United FC | Tampa Bay Rowdies | Free |
| April 1, 2021 | Thiago Santos | FC Dallas | Grêmio | Transfer |
| April 2, 2021 | Thomás Chacón | Minnesota United FC | Liverpool | Loan |
| April 2, 2021 | Jorge Gonzalez | Portland Timbers 2 | Portland Timbers | Free |
| April 2, 2021 | Jorge Gonzalez | Portland Timbers | Louisville City | Loan |
| April 2, 2021 | Ismaila Jome | Austin Bold | Portland Timbers | Free |
| April 2, 2021 | Greg Ranjitsingh | Minnesota United FC | Philadelphia Union | Free |
| April 3, 2021 | Justin McMaster | Wake Forest Demon Deacons | Minnesota United FC | SuperDraft |
| April 3, 2021 | Nabilai Kibunguchy | UC Davis Aggies | Minnesota United FC | SuperDraft |
| April 5, 2021 | Raul Aguilera | Orlando City B | Orlando City SC | Homegrown player |
| April 5, 2021 | Jack Gurr | Atlanta United 2 | Atlanta United FC | Free |
| April 5, 2021 | Kaveh Rad | Sporting Kansas City II | Sporting Kansas City | Homegrown player |
| April 5, 2021 | Gustavo Vallecilla | S.D. Aucas | FC Cincinnati | Loan |
| April 6, 2021 | Sebastian Breza | Bologna | CF Montréal | Loan |
| April 6, 2021 | Sean Rea | CF Montréal | Valour FC | Loan |
| April 6, 2021 | Jonathan Sirois | CF Montréal | Valour FC | Loan |
| April 7, 2021 | Ramón Ábila | Boca Juniors | Minnesota United FC | Loan |
| April 7, 2021 | Avionne Flanagan | South Florida Bulls | FC Cincinnati | SuperDraft |
| April 7, 2021 | Alfredo Morales | Fortuna Düsseldorf | New York City FC | Transfer |
| April 7, 2021 | Szabolcs Schön | MTK Budapest | FC Dallas | Transfer |
| April 8, 2021 | Kévin Cabral | Valenciennes | LA Galaxy | Transfer |
| April 8, 2021 | Mathieu Deplagne | FC Cincinnati | San Antonio FC | Free |
| April 8, 2021 | Alan Franco | Independiente | Atlanta United FC | Transfer |
| April 8, 2021 | Rio Hope-Gund | Georgetown Hoyas | Orlando City SC | SuperDraft |
| April 9, 2021 | Beni Redžić | North Texas SC | FC Dallas | Homegrown player |
| April 10, 2021 | Thiago Andrade | Bahia | New York City FC | Transfer |
| April 10, 2021 | Dylan Nealis | Inter Miami CF | Nashville SC | Trade |
| April 13, 2021 | Noah Billingsley | Minnesota United FC | Phoenix Rising | Loan |
| April 13, 2021 | Edgar Castillo | Atlanta United FC | FC Cincinnati | Free |
| April 15, 2021 | Tomás Conechny | Portland Timbers | Deportivo Maldonado | Free |
| April 15, 2021 | Shandon Hopeau | Seattle Sounders FC | San Antonio FC | Loan |
| April 15, 2021 | Vuk Latinovich | Milwaukee Panthers | New York City FC | SuperDraft |
| April 15, 2021 | Patrick Seagrist | Inter Miami CF | Indy Eleven | Loan |
| April 15, 2021 | Parker Siegfried | Louisville City | Sporting Kansas City | Loan |
| April 16, 2021 | Tony Alfaro | Reno 1868 | D.C. United | Free |
| April 16, 2021 | Sami Guediri | Fort Lauderdale CF | Inter Miami CF | Free |
| April 16, 2021 | Andy Najar | Los Angeles FC | D.C. United | Free |
| April 16, 2021 | Will Pulisic | Duke Blue Devils | Austin FC | Free |
| April 16, 2021 | Luke Singh | Toronto FC II | Toronto FC | Homegrown player |
| April 16, 2021 | Aedan Stanley | Duke Blue Devils | Austin FC | SuperDraft |
| April 17, 2021 | Saad Abdul-Salaam | FC Cincinnati | Columbus Crew | Free |
| April 20, 2021 | Frankie Amaya | FC Cincinnati | New York Red Bulls | Trade |
| April 22, 2021 | Patryk Klimala | Celtic | New York Red Bulls | Transfer |
| April 23, 2021 | Matteo Campagna | Vancouver Whitecaps Academy | Vancouver Whitecaps FC | Homegrown player |
| April 23, 2021 | Kamron Habibullah | Vancouver Whitecaps Academy | Vancouver Whitecaps FC | Homegrown player |
| April 23, 2021 | Adrien Hunou | Rennes | Minnesota United FC | Transfer |
| April 23, 2021 | Thomas Williamson | California Golden Bears | San Jose Earthquakes | SuperDraft |
| April 23, 2021 | Thomas Williamson | San Jose Earthquakes | Pittsburgh Riverhounds | Loan |
| April 24, 2021 | Yeferson Soteldo | Santos | Toronto FC | Transfer |
| April 28, 2021 | Séga Coulibaly | AS Nancy | LA Galaxy | Transfer |
| April 28, 2021 | Collin Smith | North Texas SC | FC Dallas | Homegrown Player |
| May 3, 2021 | Liam Fraser | Toronto FC | Columbus Crew | Loan |
| May 3, 2021 | Augustine Williams | LA Galaxy II | LA Galaxy | Transfer |
| May 7, 2021 | Kemar Lawrence | Anderlecht | Toronto FC | Transfer |
| May 11, 2021 | Dániel Gazdag | Honvéd | Philadelphia Union | Transfer |
| May 12, 2021 | Drew Skundrich | Loudoun United | D.C. United | Transfer |
| May 12, 2021 | Reed Baker-Whiting | Seattle Sounders Academy | Seattle Sounders FC | Homegrown |
| May 12, 2021 | Dom Dwyer | Orlando City SC | Toronto FC | Free |
| May 13, 2021 | Geoff Cameron | Queens Park Rangers | FC Cincinnati | Free |
| May 18, 2021 | Lisandro López | Atlanta United FC | Racing Club | Free |
| May 19, 2021 | Talles Magno | Vasco da Gama | New York City FC | Transfer |
| May 20, 2021 | Rayan Raveloson | Troyes | LA Galaxy | Transfer |
| May 20, 2021 | Jonas Fjeldberg | Dayton Flyers | FC Cincinnati | SuperDraft |
| May 21, 2021 | Andrew Thomas | Stanford Cardinal | Seattle Sounders FC | Waivers |
| May 22, 2021 | Abdoulaye Cissoko | Tacoma Defiance | Seattle Sounders FC | Transfer |
| May 26, 2021 | Jack Gurr | Atlanta United FC | Aberdeen | Free |
| May 29, 2021 | Jonathan Menéndez | Independiente | Real Salt Lake | Transfer |
| June 2, 2021 | Brian White | New York Red Bulls | Vancouver Whitecaps FC | Trade |
| June 2, 2021 | Toni Datković | Aris | Real Salt Lake | Transfer |
| June 4, 2021 | Bryce Washington | Pittsburgh Panthers | Atlanta United FC | Homegrown Player |
| June 4, 2021 | George Asomani | NC State Wolfpack | San Jose Earthquakes | SuperDraft |
| June 5, 2021 | Mamadou Fall | Montverde Academy | Los Angeles FC | MLS Waivers |
| June 8, 2021 | George Fochive | Bnei Yehuda Tel Aviv | Portland Timbers | Transfer |
| June 9, 2021 | Santiago Rodríguez | Montevideo City | New York City FC | Loan |
| June 10, 2021 | Alvas Powell | Al-Hilal Club | Philadelphia Union | Free |
| June 11, 2021 | Mamadou Fall | Los Angeles FC | Las Vegas Lights FC | Loan |
| June 14, 2021 | Facundo Quignon | Lanús | FC Dallas | Transfer |
| June 15, 2021 | Thomas Williams | Orlando City SC | Orlando City Academy | Homegrown |
| June 19, 2021 | Zackery Farnsworth | Real Salt Lake Academy | Real Salt Lake | Homegrown |
| June 25, 2021 | Nathan | FC Zürich | San Jose Earthquakes | Transfer |
| June 27, 2021 | Róbert Thorkelsson | Breiðablik | CF Montréal | Transfer |
| June 28, 2021 | Teenage Hadebe | Yeni Malatyaspor | Houston Dynamo | Transfer |
| June 28, 2021 | Christian Ramirez | Houston Dynamo | Aberdeen | Transfer |
| June 30, 2021 | Moussa Djitté | Grenoble | Austin FC | Transfer |
| July 1, 2021 | Kieran Gibbs | West Bromwich Albion | Inter Miami CF | Free |
| July 1, 2021 | Nick Marsman | Feyenoord | Inter Miami CF | Transfer |
| July 1, 2021 | Bobby Wood | Hamburger SV | Real Salt Lake | Free |
| July 2, 2021 | Jeremy Garay | D.C. United Academy | D.C. United | Homegrown Player |
| July 3, 2021 | Arquimides Ordonez | FC Cincinnati Academy | FC Cincinnati | Homegrown Player |
| July 5, 2021 | Griffin Dorsey | Toronto FC | Houston Dynamo | Free |
| July 6, 2021 | Amar Sejdic | CF Montreal | Atlanta United FC | Trade |
| July 7, 2021 | Daniel Aguirre | LA Galaxy II | LA Galaxy | Transfer |
| July 7, 2021 | Indiana Vassilev | Aston Villa | Inter Miami CF | Loan |
| July 7, 2021 | Aké Loba | Monterrey | Nashville SC | Transfer |
| July 8, 2021 | Erik Hurtado | CF Montréal | Columbus Crew | Trade |
| July 12, 2021 | Derek Cornelius | Vancouver Whitecaps FC | Panetolikos | Loan |
| July 13, 2021 | Matej Oravec | Philadelphia Union | Železiarne Podbrezová | Loan |
| July 14, 2021 | Adam Grinwis | Sacramento Republic | Orlando City SC | Free |
| July 15, 2021 | Tanner Tessmann | FC Dallas | Venezia | Transfer |
| July 17, 2021 | Emmanuel Mas | Boca Juniors | Orlando City SC | Free |
| July 17, 2021 | Tom Judge | James Madison Dukes | Nashville SC | SuperDraft |
| July 17, 2021 | Tor Saunders | Coastal Carolina Chanticleers | Nashville SC | SuperDraft |
| July 23, 2021 | Fernando Meza | Atlanta United FC | Necaxa | Free |
| July 27, 2021 | Mark-Anthony Kaye | Los Angeles FC | Colorado Rapids | Trade |
| July 29, 2021 | Sebastián Driussi | Zenit St. Petersburg | Austin FC | Free |
| July 29, 2021 | Tom Pettersson | FC Cincinnati | Lillestrøm SK | Free |
| July 29, 2021 | Dominique Badji | Nashville SC | Colorado Rapids | Trade |
| July 29, 2021 | Ventura Alvarado | San Luis | Inter Miami CF | Free |
| July 29, 2021 | Jesús Bueno | Deportivo Lara | Philadelphia Union | Transfer |
| July 29, 2021 | Santiago Moreno | América de Cali | Portland Timbers | Transfer |
| July 30, 2021 | McKinze Gaines | Hannover 96 | Austin FC | Free |
| July 30, 2021 | Corey Baird | Los Angeles FC | Houston Dynamo | Trade |
| July 30, 2021 | Giancarlo González | LA Galaxy | Alajuelense | Loan |
| July 31, 2021 | Adam Grinwis | Sacramento Republic | Orlando City Academy | Free |
| July 31, 2021 | Ryan Gauld | Farense | Vancouver Whitecaps FC | Transfer |
| August 2, 2021 | Cristian Arango | Millonarios | Los Angeles FC | Transfer |
| August 2, 2021 | Matías Pellegrini | Inter Miami CF | Estudiantes | Loan |
| August 3, 2021 | Tyler Freeman | Sporting Kansas City | Karlsruher SC | Loan |
| August 4, 2021 | Przemysław Frankowski | Chicago Fire | Lens | Transfer |
| August 5, 2021 | Adalberto Carrasquilla | Cartagena | Houston Dynamo | Loan |
| August 5, 2021 | Dejan Joveljić | Eintracht Frankfurt | LA Galaxy | Transfer |
| August 5, 2021 | Lucas Monzón | Danubio | New York Red Bulls | Loan |
| August 5, 2021 | Florian Valot | New York Red Bulls | FC Cincinnati | Trade |
| August 5, 2021 | Sam Vines | Colorado Rapids | Royal Antwerp | Transfer |
| August 5, 2021 | Jeremy Ebobisse | Portland Timbers | San Jose Earthquakes | Trade |
| August 5, 2021 | Nicolas Benezet | Colorado Rapids | Seattle Sounders FC | Trade |
| August 5, 2021 | Léo Chú | Grêmio | Seattle Sounders FC | Transfer |
| August 5, 2021 | José Mauri | Talleres | Sporting Kansas City | Free |
| August 5, 2021 | Gianluca Busio | Sporting Kansas City | Venezia | Transfer |
| August 5, 2021 | Pedro Vite | Independiente del Valle | Vancouver Whitecaps FC | Transfer |
| August 6, 2021 | Luiz Araújo | Lille | Atlanta United FC | Transfer |
| August 6, 2021 | Tyler Blackett | Nottingham Forest | FC Cincinnati | Free |
| August 6, 2021 | Niko Hämäläinen | Queens Park Rangers | LA Galaxy | Transfer |
| August 6, 2021 | Sebastien Ibeagha | New York City FC | Los Angeles FC | Trade |
| August 6, 2021 | Federico Navarro | Talleres | Chicago Fire | Transfer |
| August 6, 2021 | Joseph Rosales | Independiente Chorrera | Minnesota United FC | Loan |
| August 6, 2021 | Florian Jungwirth | San Jose Earthquakes | Vancouver Whitecaps FC | Trade |
| August 6, 2021 | Theo Bair | Vancouver Whitecaps FC | HamKam | Loan |
| August 20, 2021 | Matko Miljevic | Argentinos Juniors | CF Montréal | Transfer |
| August 20, 2021 | Marcus Godinho | FSV Zwickau | Vancouver Whitecaps FC | Free |
| August 23, 2021 | Steven Moreira | Toulouse | Columbus Crew | Free |
| August 24, 2021 | Douglas Martínez | Real Salt Lake | San Diego Loyal | Loan |
| August 27, 2021 | Simon Colyn | Vancouver Whitecaps FC | Jong PSV | Loan |
| August 31, 2021 | Jack de Vries | Philadelphia Union | Venezia | Loan |