OpenLLM-France/wikimedia huggingface dataset:
# Hacheston

Hacheston is a village and civil parish in the East Suffolk district, in the English county of Suffolk. The population of the parish at the 2011 census was 345.
It is located on the B1116 road between the towns of Wickham Market and Framlingham. Hacheston has a church and a village hall. Hacheston Halt railway station was closed in 1952.
Glevering Hall is a historic house and estate within the parish which was built in 1794 by Chaloner Arcedeckne, MP. Glevering Hall became a Grade II* listed building on 25 October 1951.

## Governance

An electoral ward in the same name exists. This ward stretches north to Bruisyard with a total population taken at the 2011 Census of 1,977.

## Notable residents

* Chaloner Arcedeckne (c. 1743–1809); MP and Jamaican landowner
* Claude Hinscliff (1875–1964); suffragist.
* Chinwe Chukwuogo-Roy MBE (1952-2012); visual artist.

## Related pages

* Hacheston Halt railway station
# 1978–79 Eerste Divisie

The Dutch Eerste Divisie in the 1978–79 season was contested by 19 teams. Excelsior won the championship.

## New entrants

Relegated from the 1977–78 Eredivisie
* FC Amsterdam
* Telstar

## League standings

| Pos | Team | Pld | W | D | L | GF | GA | GD | Pts | Promotion or qualification |
| 1 | SBV Excelsior | 36 | 22 | 7 | 7 | 76 | 32 | +44 | 51 | Promoted to Eredivisie. |
| 2 | FC Groningen | 36 | 20 | 10 | 6 | 60 | 31 | +29 | 50 | Qualified for Promotion play-off as Period champions. |
| 3 | Willem II | 36 | 17 | 14 | 5 | 60 | 32 | +28 | 48 | Qualified for Promotion play-off as Period champions. |
| 4 | Fortuna SC | 36 | 17 | 13 | 6 | 64 | 35 | +29 | 47 | Qualified for Promotion play-off as Period champions. |
| 5 | FC Eindhoven | 36 | 14 | 16 | 6 | 53 | 32 | +21 | 44 | |
| 6 | FC Wageningen | 36 | 17 | 10 | 9 | 59 | 44 | +15 | 44 | |
| 7 | FC Den Bosch | 36 | 16 | 10 | 10 | 58 | 43 | +15 | 42 | |
| 8 | De Graafschap | 36 | 15 | 11 | 10 | 60 | 47 | +13 | 41 | |
| 9 | FC Amsterdam | 36 | 13 | 11 | 12 | 52 | 40 | +12 | 37 | |
| 10 | Telstar | 36 | 12 | 10 | 14 | 45 | 45 | 0 | 34 | Qualified for Promotion play-off as Period champions. |
| 11 | sc Heerenveen | 36 | 10 | 13 | 13 | 34 | 47 | −13 | 33 | |
| 12 | SC Veendam | 36 | 13 | 6 | 17 | 51 | 67 | −16 | 32 | |
| 13 | SC Heracles | 36 | 10 | 11 | 15 | 46 | 49 | −3 | 31 | |
| 14 | SVV | 36 | 11 | 9 | 16 | 42 | 48 | −6 | 31 | |
| 15 | SC Cambuur | 36 | 9 | 10 | 17 | 33 | 54 | −21 | 28 | |
| 16 | FC Vlaardingen | 36 | 7 | 12 | 17 | 35 | 54 | −19 | 26 | |
| 17 | Helmond Sport | 36 | 9 | 8 | 19 | 42 | 71 | −29 | 26 | |
| 18 | SC Amersfoort | 36 | 8 | 7 | 21 | 34 | 78 | −44 | 23 | |
| 19 | FC Dordrecht | 36 | 5 | 6 | 25 | 33 | 88 | −55 | 16 | Changed name to DS '79 for next season. |

## Promotion competition

In the promotion competition, four period winners (the best teams during each of the four quarters of the regular competition) played for promotion to the Eredivisie.
| Pos | Team | Pld | W | D | L | GF | GA | GD | Pts | Promotion |
| 1 | Willem II | 6 | 3 | 2 | 1 | 9 | 5 | +4 | 8 | Promoted to Eredivisie. |
| 2 | Fortuna SC | 6 | 3 | 2 | 1 | 7 | 4 | +3 | 8 | Changed name to Fortuna Sittard for next season. |
| 3 | FC Groningen | 6 | 2 | 2 | 2 | 6 | 6 | 0 | 6 | |
| 4 | Telstar | 6 | 1 | 0 | 5 | 5 | 12 | −7 | 2 | |
# 1975–76 Eerste Divisie

The Dutch Eerste Divisie in the 1975–76 season was contested by 19 teams. HFC Haarlem won the championship.

## New entrants

Relegated from the 1974–75 Eredivisie
* HFC Haarlem
* FC Wageningen

## League standings

| Pos | Team | Pld | W | D | L | GF | GA | GD | Pts | Promotion or qualification |
| 1 | HFC Haarlem | 36 | 23 | 9 | 4 | 78 | 36 | +42 | 55 | Promoted to Eredivisie. |
| 2 | VVV-Venlo | 36 | 21 | 7 | 8 | 61 | 33 | +28 | 49 | Qualified for Promotion play-off as Period Champions. |
| 3 | FC Wageningen | 36 | 17 | 10 | 9 | 52 | 27 | +25 | 44 | Qualified for Promotion play-off as Period Champions. |
| 4 | FC Groningen | 36 | 15 | 12 | 9 | 52 | 29 | +23 | 42 | |
| 5 | Vitesse Arnhem | 36 | 13 | 16 | 7 | 58 | 35 | +23 | 42 | Qualified for Promotion play-off as Period Champions. |
| 6 | PEC Zwolle | 36 | 14 | 14 | 8 | 51 | 35 | +16 | 42 | |
| 7 | Fortuna SC | 36 | 17 | 8 | 11 | 48 | 45 | +3 | 42 | Qualified for Promotion play-off as Period Champions. |
| 8 | SC Veendam | 36 | 15 | 10 | 11 | 46 | 39 | +7 | 40 | |
| 9 | Willem II | 36 | 13 | 10 | 13 | 53 | 65 | −12 | 36 | |
| 10 | FC Den Bosch | 36 | 12 | 10 | 14 | 44 | 47 | −3 | 34 | |
| 11 | SC Cambuur | 36 | 12 | 10 | 14 | 50 | 56 | −6 | 34 | |
| 12 | FC Dordrecht | 36 | 12 | 9 | 15 | 46 | 53 | −7 | 33 | |
| 13 | sc Heerenveen | 36 | 12 | 8 | 16 | 39 | 49 | −10 | 32 | |
| 14 | FC Volendam | 36 | 10 | 10 | 16 | 45 | 57 | −12 | 30 | |
| 15 | SC Heracles | 36 | 12 | 5 | 19 | 38 | 54 | −16 | 29 | |
| 16 | Helmond Sport | 36 | 9 | 11 | 16 | 34 | 51 | −17 | 29 | |
| 17 | FC Vlaardingen | 36 | 7 | 11 | 18 | 40 | 52 | −12 | 25 | |
| 18 | SC Amersfoort | 36 | 8 | 9 | 19 | 39 | 66 | −27 | 25 | |
| 19 | SVV | 36 | 6 | 9 | 21 | 31 | 76 | −45 | 21 | |

## Promotion competition

In the promotion competition, four period winners (the best teams during each of the four quarters of the regular competition) played for promotion to the Eredivisie.
| Pos | Team | Pld | W | D | L | GF | GA | GD | Pts | Promotion |
| 1 | VVV-Venlo | 6 | 4 | 1 | 1 | 8 | 4 | +4 | 9 | Promoted to Eredivisie. |
| 2 | Fortuna SC | 6 | 3 | 1 | 2 | 14 | 10 | +4 | 7 | |
| 3 | Vitesse Arnhem | 6 | 2 | 2 | 2 | 8 | 9 | −1 | 6 | |
| 4 | FC Wageningen | 6 | 0 | 2 | 4 | 7 | 14 | −7 | 2 | |
# José Enrique Reina Lizárraga

José Enrique Reina Lizárraga (born 12 August 1969) is a Mexican politician affiliated with the National Action Party (PAN). He served as a federal deputy during the 62nd session of Congress, representing Sonora's first district. He had previously served as a local deputy in the 59th session of the Congress of Sonora. He was also the mayor of San Luis Río Colorado from 2000 to 2003 and 2015 to 2018.
# Vous permettez, Monsieur?

"Vous permettez, Monsieur?" is a song by Italian-Belgian singer, Salvatore Adamo. The song topped the Tijd Voor Teenagers Top 10 chart for eleven weeks and ended up being the best-selling single of the year in the Netherlands by the close of 1964, with over 200,000 copies sold. It also achieved the highest ranking on the annual points-based list.
The lyrics narrate a story where a young man wishes to take a girl to a party and, in accordance with tradition, seeks her father's permission. He assures the father that he will conduct himself properly, just as the father did before his own marriage.
Adamo's rendition of this song on the show Voor de vuist weg, accompanied by his much younger brother and sisters, left a lasting impression on the audience.

## Charts

| Chart (1963–1965) | Peak position |
| Belgium (Ultratop 50 Flanders) | 1 |
| Belgium (Ultratop 50 Wallonia) | 1 |
| France (IFOP) | 1 |
| Switzerland (Swiss Hitparade) | 13 |
| Netherlands (Dutch Top 40) | 1 |
| West Germany (Media Control) | 34 |
# Muhammad-Shah II

Muhammad-Shah II (c. 1147 – 1187) was the last Seljuk amir of Kerman, from 1183 until 1186.

## Biography

The son of Bahram-Shah, Muhammad-Shah succeeded his uncle Turan-Shah to the throne of Kerman in 1183. By the time of his ascension Kerman had been overrun by bands of Ghuzz Turks. Their devastation of the province had made the city of Bardasir virtually uninhabitable, so Muhammad-Shah made Bam his capital. By 1186, however, Muhammad-Shah been unable to handle the Ghuzz, and he decided to abandon Bam and departed from Kerman. The Ghuzz chief Malik Dinar quickly seized control of Kerman in his place.
Muhammad-Shah at first hoped to receive foreign assistance to reacquire Kerman, and traveled to Fars and Iraq requesting help. He also sought for aid from the Khwarezmshah Ala ad-Din Tekish. Eventually, however, he realized that he could get no assistance in recovering Kerman. He made his way to the Ghurid Empire and spent the remainder of his life in the service of the Ghurid sultans.
# Academia Militară metro station

Academia Militară is a station on line M5 of Bucharest Metro. It is located between Eroilor and Orizont. The station was opened on 15 September 2020 as part of the inaugural section of M5, from Eroilor to Valea Ialomiței and Râul Doamnei. It is named for the nearby Carol I National Defence University.
# Finn Amundsen

Finn Amundsen (29 May 1897 – 18 May 1958) was a Norwegian sports journalist, radio reporter, non-fiction writer and translator. He was born in Kristiania. He was journalist and later editor of the sports magazine Idrætsliv, until 1932, and from then sports editor of the newspaper Morgenbladet. He became legendary as radio sports reporter, in particular on skating. He was also active for SFK Lyn and refereed the 1938 Norwegian Football Cup Final.
# Patria Jiménez

Patria Jiménez (born Elsa Patria Jiménez Flores in 1957 in San Luis Potosí, Mexico) is a Mexican politician and head of El Clóset de Sor Juana (Sister Juana's Closet). In 1997, representing the PRD. Openly lesbian, she became the first gay member of Mexico's legislature in the country's history—the first in any legislature in Latin America.
Jiménez is the longtime head of Sister Juana's Closet, a lesbian rights group named after Juana Inés de la Cruz, a Carmelite nun and renowned Mexican poet. It is a United Nations accredited Non-Governmental Organization (NGO).
Both as a civil rights leader and a member of the government, Jimenez is a major Latin American voice for LGBT rights and civil rights in general.

## Political career

Jiménez is a member of the Party of the Democratic Revolution (PRD). In 1997 she was elected federal deputy hence she served during the LVII Legislature of the Mexican Congress. In 2000 she was elected substitute Senator but took office in the senate until 2006 when senator Demetrio Sodi left that position therefore she served as senator during the final months of the LIX Legislature.
# South Sudan Football Championship

The South Sudan Football Championship is the second-tier division of the South Sudan Football Association. The first season started in 2011 after the independence of South Sudan. Seven provincial champions entered and Al-Salam FC won. They went on to represent South Sudan in the 2012 Kagame Interclub Cup of CECAFA. Atlabara won the second championship in 2013, then participated in the 2014 CAF Champions League.

## History

The South Sudan National Champions also Known as South Sudan Cup is the second-tier football league in South Sudan. It was established in 2011 shortly after the independent of South Sudan.

## 2024 season

The final 2024 South Sudan Football Championship standings:
| # | Football club | Location | W | D | L | Pts |
| 1 | El-Merrikh | Bentiu | 3 | 0 | 1 | 9 |
| 2 | Malakia SC | Juba | 1 | 2 | 1 | 5 |
| 3 | Salam FC | Aweil | 0 | 2 | 2 | 2 |
Highest attendance: 2,000 at El-Merrikh vs Malakia SC.

## Previous winners

| Years | Champions |
| 2012 | Al-Salam (1) |
| 2013 | Atlabara (1) |
| 2014 | Al-Malakia (1) |
| 2015 | Atlabara (2) |
| 2016 | Not held |
| 2017 | Al-Salam (2) |
| 2018 | Al-Hilal (1) |
| 2019 | Atlabara (3) |
| 2020 | Championship not finished due to Covid-19 |
| 2021 | Not held |
| 2022 | Not held |
| 2023 | Bor Salaam (1) |
| 2024 | Al Merreikh (1) |

## Performance by club

| Club | Winners | Winning Years |
| Atlabara | 3 | 2013, 2015, 2019 |
| Al-Salaam | 2 | 2011–12, 2017 |
| Al-Malakia | 1 | 2014 |
| Al-Hilal Wau | 1 | 2018 |
| Salaam (Bor) | 1 | 2023 |
| Al Merreikh | 1 | 2024 |
# Ibrahim Babangida College of Agriculture

The Ibrahim Babangida College of Agriculture is a tertiary educational institution in Obubra, Cross River State, Nigeria. 20 million naira was allocated for infrastructure development in 2001, but only 3.9 million was reported as spent. No further allocations were provided in 2002–2005. In 2002, the college infrastructure was in decay, and it was described as "more or less a glorified secondary school." The National Youth Service Corps included the college in its list of institutions from which graduates in 2008 had to go on to undertake NYSC service. As of 2010, it was not shown as an approved college of agriculture by the National Board for Technical Education. The current Vice Chancellor of the Ibrahim Badamasi Babangida College of Agriculture is Professor Abu Kasim Adamu and he's doing great to see the reputation of the school is doing great.
# Paul Andrew Hutton

Paul Andrew Hutton is an American writer, and television personality. He is also Distinguished Professor of History at the University of New Mexico and the former executive director of Western History Association and past president of Western Writers of America.

## Career
### Research and literary works

At the University of New Mexico, Hutton helped to gather information about George Armstrong Custer for the readers. The result of Hutton's research was The Custer Reader, a collection of essays, photographs, and fiction regarding Custer and his complex personality. Hutton's 1985 book Phil Sheridan and His Army received many awards for historical writing, including the Ray Allen Billington Award. Other books he has written include:
* The Apache Wars: The Hunt for Geronimo. New York City: Bantam Books. 2017. ISBN 978-07-70435-83-7.
He has written many other award-winning essays, scripts, and articles. He has done a great deal of work in television documentaries, and was a historical consultant for the films The Missing and "Cowboys and Aliens". Dr Hutton has appeared in, written or narrated over 150 television documentaries on CBS, NBC, PBS, Discover, Disney Channel, TBS, TNN, A&E, and the History Channel. Listed below are recent samples of his work.

### Film and television writing credits

* Eighty Acres of Hell (TV) – (writer) (2006)
* Investigating History TV series – (unknown episodes) (2003)
* Carson and Cody: The Hunter Heroes (TV) – (writer) (2003)
Hutton also served as the President of the Western Writers of America from 2002 to 2004.

### Television producing credits

* Investigating History – TV series (co-producer) (unknown episodes) (2003)
* Carson and Cody: The Hunter Heroes – (2003) (TV) (producer)

### Television and film appearances

As self:
* The Real West (A&E) – 60 episodes (1993–2006)
* Biography – Billy the Kid (2006)
* Biography – The James Gang: Outlaw Brothers (TV episode) (1995)
* CBS – Wyatt Earp: Walk with a Legend (TV)(1994)
* American Experience: Wyatt Earp (2010)
* American Experience: Custer's Last Stand (2012)
* American Experience: Butch Cassidy & The Sundance Kid (2014)
As actor:
* Naked Gun 33+1⁄3: The Final Insult (1991) as Doctor
Hutton made his cameo appearance in the movie Naked Gun 33 1⁄3 (as a doctor at the very end of the film) while he was collaborating with David Zucker on a screenplay about Davy Crockett.

## Personal

A native German, adopted by an American Air Force couple, he was reared primarily in England, Texas, Taiwan, and Indiana. Hutton married the former Vicki Bauer on July 25, 1972. They had a daughter. They were divorced August 1984. He then married Lynn Brittner in 1989 and they had two children. They eventually divorced.
He married Tracy Cogdill in 2001 and adopted her two daughters from a previous marriage.

## Education

Dr Hutton graduated with a B.A. in History from Indiana University Bloomington, in 1972, where he also obtained his M.A. (1974) and his Ph.D. in History (1981).
# First National Bank of Greenville

The First National Bank of Greenville is a historic building in Greenville, Mississippi.

## Location

The building is located at 302 Main Street in Greenville, Washington County, Mississippi.

## History

It was built in 1903 as the headquarters of the first bank chartered by the United States federal government in Washington County, Mississippi. It was designed in the Neoclassical architectural style by Knoxville, Tennessee architects Barber & Kluttz. It was established by James E. Negus, Jr., a Civil War veteran who had served in the Union Army and moved to Mississippi in 1870.
It is now used as a public building for the Greenville Municipal Court.

## Heritage significance

It has been listed on the National Register of Historic Places since January 30, 1978.
It was listed again on the National Register in 1997 as a contributing building in the Greenville Commercial Historic District.
# Middle States Commission on Higher Education

The Middle States Commission on Higher Education, abbreviated as MSCHE and legally incorporated as the Mid-Atlantic Region Commission on Higher Education, is a voluntary, peer-based, non-profit membership organization that performs peer evaluation and accreditation of public and private universities and colleges in the United States and foreign higher education institutions. Its headquarters are in Wilmington, Delaware.
Until federal regulations changed in July 2020, it was considered one of the seven regional accreditation organizations dating back 130 years. The commission is recognized by the U.S. Department of Education and the Council for Higher Education Accreditation. It accredits nearly 600 institutions, primarily in Delaware, Washington, D.C., Maryland, New Jersey, New York, Pennsylvania, Puerto Rico, and the U.S. Virgin Islands.

## Region and scope

The Middle States Commission on Higher Education is recognized by the U.S. Department Education to accredit degree-granting institutions. Its traditional region includes the U.S. states of New York, New Jersey, Pennsylvania, Delaware, and Maryland, and Washington, D.C. and the American territories and commonwealths of Puerto Rico, and the U.S. Virgin Islands that wish to participate in Federal "Title IV" student loan programs. The commission conducts business in 48 states; the two exceptions are Montana and North Dakota, two U.S. territories, Puerto Rico and the U.S. Virgin Islands, and Washington, D.C.. It operates in 94 countries.

## History

MSCHE grew out of the Middle States Association of Colleges and Schools (MSA), an organization established in 1887 to improve education using evaluation and accreditation. MSCHE itself was established in 1919 and was one of three commissions of MSA until 2013 when MSCHE incorporated as a separate entity in Pennsylvania as the Mid-Atlantic Region Commission on Higher Education doing business as the Middle States Commission on Higher Education. On July 1, 2019, MSCHE withdrew from MSA completely.
# Steven van der Sloot

Steven Ako van der Sloot (born 6 July 2002) is a Dutch professional footballer who plays as a right-back for Eerste Divisie club ADO Den Haag.

## Club career

Van der Sloot made his first team debut for Schalke 04 in the 2. Bundesliga in a 1–1 away draw against Hannover 96 on 7 April 2024, coming on as a substitute in the 84th minute for Cédric Brunner.
Sloot signed a 2-year contract with Eerste Divisie club ADO Den Haag on 6 July 2024.

## International career

Van der Sloot was born in Cameroon to a Dutch father and a Cameroonian mother, and holds dual citizenship. He was a youth international for the Netherlands.

## Career statistics

    As of match played 22 December 2024
| Club | Season | League | League | League | Cup | Cup | Total | Total |
| Club | Season | Division | Apps | Goals | Apps | Goals | Apps | Goals |
| Jong Ajax | 2020–21 | Eerste Divisie | 3 | 0 | — | — | 3 | 0 |
| Jong Ajax | 2021–22 | Eerste Divisie | 10 | 0 | — | — | 10 | 0 |
| Jong Ajax | Total | Total | 13 | 0 | — | — | 13 | 0 |
| Schalke 04 II | 2022–23 | Regionalliga West | 19 | 3 | — | — | 19 | 3 |
| Schalke 04 II | 2023–24 | Regionalliga West | 25 | 0 | — | — | 25 | 0 |
| Schalke 04 II | Total | Total | 44 | 3 | — | — | 44 | 3 |
| Schalke 04 | 2023–24 | 2. Bundesliga | 7 | 0 | 0 | 0 | 7 | 0 |
| ADO Den Haag | 2024–25 | Eerste Divisie | 19 | 0 | 1 | 0 | 20 | 0 |
| Career total | Career total | Career total | 83 | 3 | 1 | 0 | 84 | 3 |

## Honours

Netherlands U17
* UEFA European Under-17 Championship: 2019
# Karachi Port Trust Halt railway station

Karachi Port Trust Halt railway station (Urdu: کراچی پورٹ ٹرسٹ ہالٹ ریلوے اسٹیشن, Sindhi: ڪراچي پورٽ ٽرسٽ هالٽ ريلوي اسٽيشن) is located in Karachi, Pakistan.
# Baldia railway station

Baldia railway station (Urdu: بلدیہ ریلوے اسٹیشن, is located in Karachi, Pakistan.
# SITE railway station

SITE railway station (Urdu: سائٹ ریلوے اسٹیشن, Sindhi: سائيٽ ريلوي اسٽيشن) is located in Karachi, Pakistan, and serves the Sindh Industrial Trading Estate (SITE), one of Asia's largest industrial estates.
# Tawatwong na Chiang Mai

Tawatwong Na Chiang Mai (Thai: ธวัชวงศ์ ณ เชียงใหม่; RTGS: Thawatwong Na Chiangmai, December 14, 1945- ) is a Thailand politician who served as Thailand's Deputy Minister of Finance from 1996 until 1997, Deputy Minister of Public Health from 1996 until 1997 and the Deputy Minister of Foreign Affairs 1997.

## History

Prince Tawatwong Na Chiang Mai was born on December 14, 1945. He is the son of Chao Chaisuriwong Na Chiang Mai and Mae Tem. He had the nickname "Prince Nuy." In 1952 he began his studies at Montfort College in Chiang Mai and in 1965 he transferred to the North Carolina State University in North Carolina.

## Royal decorations

* Knight Grand Cordon (Special Class) of the Most Exalted Order of the White Elephant
* Knight Grand Cordon (Special Class) of The Most Noble Order of the Crown of Thailand
# Stercobilin

Stercobilin is a tetrapyrrolic bile pigment and is one end-product of heme catabolism. It is the chemical responsible for the brown color of human feces and was originally isolated from feces in 1932. Stercobilin (and related urobilin) can be used as a marker for biochemical identification of fecal pollution levels in rivers.

## Metabolism

Stercobilin results from breakdown of the heme moiety of hemoglobin found in erythrocytes (red blood cells). Macrophages break down senescent erythrocytes and break the heme down into biliverdin, which rapidly reduces to free bilirubin. Bilirubin binds tightly to plasma proteins (especially albumin) in the blood stream and is transported to the liver, where it is conjugated with one or two glucuronic acid residues into bilirubin diglucuronide, and secreted into the small intestine as bile. In the small intestine, some bilirubin glucuronide is converted back to bilirubin via bacterial enzymes in the terminal ileum. This bilirubin is further converted to colorless urobilinogen by the bacterial enzyme bilirubin reductase. Urobilinogen that remains in the colon can either be reduced to stercobilinogen and finally oxidized to stercobilin, or it can be directly reduced to stercobilin. Stercobilin is responsible for the brown color of human feces. Stercobilin is then excreted in the feces.

## Role in disease
### Obstructive jaundice

In obstructive jaundice, no bilirubin reaches the small intestine, meaning that there is no formation of stercobilinogen. The lack of stercobilin and other bile pigments causes feces to become clay-colored.

### Brown pigment gallstones

An analysis of two infants suffering from cholelithiasis observed that a substantial amount of stercobilin was present in brown pigment gallstones. This study suggested that brown pigment gallstones could form spontaneously in infants suffering from bacterial infections of the biliary tract.

## Role in treatment of disease

A 1996 study by McPhee et al. suggested that stercobilin and other related pyrrolic pigments — including urobilin, biliverdin, and xanthobilirubic acid — has potential to function as a new class of HIV-1 protease inhibitors when delivered at low micromolar concentrations. These pigments were selected due to a similarity in shape to the successful HIV-1 protease inhibitor Merck L-700,417 (N,N-bis(2-hydroxy-1-indanyl)-2,6-diphenylmethyl-4-hydroxy-1,7-heptandiamide). Further research is suggested to study the pharmacological efficacy of these pigments.