# 2001 Campionati Internazionali di Sicilia – Singles

Olivier Rochus was the defending champion but did not compete that year.
Félix Mantilla won in the final 7–6$^{(7–2)}$, 6–4 against David Nalbandian.

## Seeds

A champion seed is indicated in bold text while text in italics indicates the round in which that seed was eliminated.
* Àlex Corretja (second round)
* Carlos Moyá (first round)
* Albert Portas (semifinals)
* Tommy Robredo (semifinals)
* Albert Costa (quarterfinals)
* Andreas Vinciguerra (second round)
* Franco Squillari (second round)
* Galo Blanco (second round)

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking
| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final |
| WC/1 | À Corretja | 7 | 6 | | | | | | | | | | | | | | | | | | | |
| Q | M Puerta | 5 | 4 | | WC/1 | À Corretja | 4 | 5 | | | | | | | | | | | | | | |
| | M Zabaleta | 6 | 6 | | | M Zabaleta | 6 | 7 | | | | | | | | | | | | | | |
| | S Bruguera | 3 | 1 | | | | | | | | M Zabaleta | 0 | 0 | r | | | | | | | | |
| | A Montañés | 6 | 6$^2$ | 2 | | | | | | | F Mantilla | 6 | 2 | | | | | | | | | |
| | F Mantilla | 3 | 7$^7$ | 6 | | F Mantilla | 6 | 6 | | | | | | | | | | | | | | |
| Q | J García-Sintes | 3 | 1 | | 8 | G Blanco | 3 | 1 | | | | | | | | | | | | | | |
| 8 | G Blanco | 6 | 6 | | | | | | | | | | | | | F Mantilla | 2 | 7$^7$ | 6 | | | |
| 3 | A Portas | 4 | 6 | 6 | | | | | | | | | | | 3 | A Portas | 6 | 6$^4$ | 3 | | | |
| WC | F Volandri | 6 | 3 | 4 | 3 | A Portas | 7$^7$ | 4 | 6 | | | | | | | | | | | | | |
| Q | O Gross | 6$^4$ | 1 | | | J Acasuso | 6$^2$ | 6 | 3 | | | | | | | | | | | | | |
| | J Acasuso | 7$^7$ | 6 | | | | | | | 3 | A Portas | 6 | 6 | | | | | | | | | |
| | D Sánchez | 6 | 4 | 7$^7$ | | | | | | | D Sánchez | 3 | 3 | | | | | | | | | |
| Q | M-K Goellner | 2 | 6 | 6$^4$ | | D Sánchez | 6 | 2 | | | | | | | | | | | | | | |
| | J Balcells | 6$^6$ | 7 | 2 | 7 | F Squillari | 3 | 0 | r | | | | | | | | | | | | | |
| 7 | F Squillari | 7$^8$ | 5 | 6 | | | | | | | | | | | | | | | | Félix Mantilla | 7$^7$ | 6 |
| 6 | A Vinciguerra | 6 | 6 | | | | | | | | | | | | | | | | | David Nalbandian | 6$^2$ | 4 |
| | K Alami | 1 | 2 | | 6 | A Vinciguerra | 6$^2$ | 2 | | | | | | | | | | | | | | |
| | J Díaz | 3 | 3 | | | J Vaněk | 7$^7$ | 6 | | | | | | | | | | | | | | |
| | J Vaněk | 6 | 6 | | | | | | | | J Vaněk | 3 | 6$^5$ | | | | | | | | | |
| WC | R Carretero | 5 | 1 | | | | | | | 4 | T Robredo | 6 | 7$^7$ | | | | | | | | | |
| | H Armando | 7 | 6 | | | H Armando | 6$^3$ | 2 | | | | | | | | | | | | | | |
| | G Puentes | 3 | 0 | | 4 | T Robredo | 7$^7$ | 6 | | | | | | | | | | | | | | |
| 4 | T Robredo | 6 | 6 | | | | | | | | | | | | 4 | T Robredo | 2 | 6$^4$ | | | | |
| 5 | A Costa | 6 | 6 | | | | | | | | | | | | | D Nalbandian | 6 | 7$^7$ | | | | |
| | J Delgado | 1 | 3 | | 5 | A Costa | 6 | 6 | | | | | | | | | | | | | | |
| | F Luzzi | 4 | 6 | 6 | | F Luzzi | 2 | 1 | | | | | | | | | | | | | | |
| | M Hipfl | 6 | 3 | 4 | | | | | | 5 | A Costa | 4 | 6 | 5 | | | | | | | | |
| | F Vicente | 6 | 3 | | | | | | | | D Nalbandian | 6 | 3 | 7 | | | | | | | | |
| | A Gaudenzi | 1 | 0 | r | | F Vicente | 4 | 4 | | | | | | | | | | | | | | |
| | D Nalbandian | 6 | 4 | 6 | | D Nalbandian | 6 | 6 | | | | | | | | | | | | | | |
| 2 | C Moyá | 2 | 6 | 3 | | | | | | | | | | | | | | | | | | |