OpenLLM-France/wikimedia huggingface dataset:
# AKR1B1

Aldo-keto reductase family 1, member B1 (AKR1B1) is an gene in humans that encodes the enzyme aldose reductase. It is a reduced nicotinamide-adenine dinucleotide phosphate (NADPH)-dependent enzyme catalyzing the reduction of various aldehydes and ketones to the corresponding alcohol. The involvement of AKR1B1 in oxidative stress diseases, cell signal transduction, and cell proliferation process endows AKR1B1 with potential as a therapeutic target.

## Structure
### Gene

The AKR1B1 gene lies on the chromosome location of 7q33 and consists of 10 exons. There are a few putative pseudogenes for this gene, and one of them has been confirmed and mapped to chromosome 3.

### Protein

AKR1B1 consists of 316 amino acid residues and weighs 35853Da. It does not possess the traditional dinucleotide binding fold. The way it binds NADPH differs from other nucleotide adenine dinucleotide-dependent enzymes. The active site pocket of human aldose reductase is relatively hydrophobic, lined by seven aromatic and four other non-polar residues.

## Function

AR belongs to the aldehyde-keto reductase superfamily, with a widely expression in human organs including the kidney, lens, retina, nerve, heart, placenta, brain, skeletal muscle, testis, blood vessels, lung, and liver. It is a reduced nicotinamide-adenine dinucleotide phosphate (NADPH)-dependent enzyme catalyzing the reduction of various aldehydes and ketones to the corresponding alcohol. It also participates in glucose metabolism and osmoregulation and plays a protective role against toxic aldehydes derived from lipid peroxidation and steroidogenesis.

## Clinical significance

Under diabetic conditions AR converts glucose into sorbitol, which is then converted to fructose. 20466987 It has been found to play an important role in many diabetes complications such as diabetes retinopathy and renopathy. It is also involved in many oxidative stress diseases, cell signal transduction, and cell proliferation process including cardiovascular disorders, sepsis, and cancer.
It has been reported that the action of AR contributes to the activation of retinal microglia, suggesting that inhibition of AR may be of a therapeutic importance to reduce inflammation associated with activation of RMG. Adapting AR inhibitors could as well prevent sepsis complications, prevent angiogenesis, ameliorate mild or asymptomatic diabetic cardiovascular autonomic neuropathy and may be a promising strategy for the treatment of endotoxemia and other ROS-induced inflammatory diseases.

## Interactions

AKR1B1 has been found to interact with:
* ginsenoside 20(S)-Rh2
* alkaloid
* carboxylic acid derivatives
* spirohydantoins
* cyclic amides
# Salina Township, Kankakee County, Illinois

Salina Township is one of seventeen townships in Kankakee County, Illinois, USA. As of the 2010 census, its population was 1,396 and it contained 537 housing units. It was formed from part of Limestone Township on April 7, 1854.

## Geography

According to the 2010 census, the township has a total area of 36.59 square miles (94.8 km$^2$), all land.

### Cities, towns, villages

* Bonfield

### Unincorporated towns

* Frielings at 41°09′58″N 88°06′47″W﻿ / ﻿41.166°N 88.113°W﻿ / 41.166; -88.113
(This list is based on USGS data and may include former settlements.)

### Adjacent townships

* Rockville Township (northeast)
* Limestone Township (east)
* Pilot Township (south)
* Essex Township (west)
* Custer Township, Will County (northwest)

### Cemeteries

The township contains these three cemeteries: Beach, Bonfield and Maple Grove.

### Major highways

* Illinois Route 17

### Airports and landing strips

* Hawker Airport

### Landmarks

* Kankakee River State Park

## Government

The township is governed by an elected Town Board of a Supervisor and four Trustees. The Township also has an elected Assessor, Clerk, Highway Commissioner and Supervisor. The Township Office is located at 3388 North 10000 West Road, Bonfield, IL 60913.

## Political districts

* Illinois's 11th congressional district
* State House District 75
* State Senate District 38

## School districts

* Herscher Community Unit School District 2
# Friends of the Parks

Friends of the Parks (FOTP) is a non-profit organization in Chicago, Illinois. Formed in 1975, it acts as a watchdog group and environmental advocate for the Chicago area. Specifically, it monitors the condition and safety of the Chicago Park District and the forest preserves of Cook County.
FOTP's office is in downtown Chicago. Its staff of approximately eight people relies on volunteer efforts for many of its activities.
Annual events organized by FOTP include the Earth Day Parks and Preserves Clean-up, mobilizing several thousand volunteers on a single day in April to beautify and clean over 100 Chicago area locations; and a black tie ball which features a charity auction.
FOTP provides environmental education programs for Chicago students through two programs: Nature Along the Lake (NAL) for elementary students, and the Earth Team, an after-school apprenticeship program for high school students.
FOTP encourages grassroots efforts to organize local park organizations and acts as a liaison for organizing volunteer events to maintain and improve Chicago area parks, forest preserves, and other greenspace.
On May 3, 2016, a statement released by Melody Hobson stated that the Lucas Museum of Narrative Art would seek a location outside Chicago after a protracted confrontation with FOTP over plans that would have erected a private museum with public greenspace in place of a lakefront parking lot.
In May 2018, Juanita Irizarry, Executive Director, said that Friends of the Parks "disagree with the choice to locate [the Obama Center] on public parkland rather than vacant land across the street from Washington Park." Nonetheless, Friends of the Parks did not join the lawsuit initiated by Protect our Parks against the Obama Center.
# 2S7

2S7 can refer to:
* 2S7 Pion, a Soviet/Russian self-propelled gun
* 2S7, the FAA location identifier for Chiloquin State Airport
# Caroline Neville Pearre

Caroline Neville Pearre (1834–1910) began the Christian Woman's Board of Missions (CWBM) in 1874, after she felt that she was called to do so by God. Pearre was living in Iowa City, Iowa at the time, having taught at Christian colleges in Missouri, Kentucky and Ohio. The wife of a Disciples of Christ pastor, Pearre organized a missionary society in her own church in Iowa City. Friends of hers in other Christian churches organized similar missionary societies in their churches. These various societies united and formed the American Christian Missionary Society which became the Christian Women's Board of Missions (CWBM).
Pearre died in 1910, in her sister's home in Kentucky. She was buried in Lexington.
# Sherborne House

Sherborne House is the name of more than one house in Britain. It may refer to:
* Sherborne House, Dorset
* Sherborne House, Gloucestershire
# Gran Premio Jockey Club (Uruguay)

The Gran Premio Jockey Club is a Group I flat race for three-year-olds, run over a distance of 2000 metres every October in Maroñas racetrack in Montevideo, Uruguay. It is the second leg of the Uruguayan Triple Crown for three year-olds.
# 2007 World Archery Championships – Men's individual compound

The men's individual compound competition at the 2007 World Archery Championships took place in July 2007 in Leipzig, Germany. 139 archers entered the competition. Following a qualifying FITA round, the top 128 archers qualified for the 7-round knockout round, drawn according to their qualification round scores. The semi-finals and finals then took place on 15 July.

## Qualifying

The following archers were the leading 16 qualifiers:
* Rodger Willett Jr. (3rd round)
* Morten Bøe (4th round)
* Sergio Pagni (3rd round)
* Morgan Lundin (3rd round)
* Martin Damsbo (3rd place)
* Braden Gellenthien (2nd place)
* Jari Haavisto (3rd round)
* Patrick Coghlan (Quarterfinal)
* Majid Ahmadi (3rd round)
* Jorge Jiménez (2nd round)
* Peter Elzinga (1st round)
* Reo Wilde (3rd round)
* Marko Jarvenpaa (3rd round)
* Clint Freeman (Quarterfinal)
* Emiel Custers (3rd round)
* Reza Amaninejad (2nd round)

## Finals

| Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Finals | Finals | Finals |
| 32 | Dietmar Trillus | 116 | | | | | | |
| 8 | Patrick Coghlan | 115 | | | | | | |
| 8 | Patrick Coghlan | 115 | 32 | Dietmar Trillus | 114 | | | |
| | | | 5 | Martin Damsbo | 113 | | | |
| 5 | Martin Damsbo | 114 | 5 | Martin Damsbo | 113 | | | |
| 20 | Kevin Tataryn | 108 | | | | | | |
| 20 | Kevin Tataryn | 108 | | | | 32 | Dietmar Trillus | 116$^{10}$ |
| | | | | | | 6 | Braden Gellenthien | 116$^9$ |
| 14 | Clint Freeman | 110 | | | | | | | 6 | Braden Gellenthien | 116$^9$ |
| 6 | Braden Gellenthien | 115 | | | |
| 6 | Braden Gellenthien | 115 | 6 | Braden Gellenthien | 117 | Third place | Third place | Third place |
| | | | 23 | Jose Duo | 114 |
| 23 | Jose Duo | 114 | 23 | Jose Duo | 114 | 5 | Martin Damsbo | 115 |
| 18 | Sebastien Brasseur | 112 | | | | 23 | Jose Duo | 111 |
# Casteggio

Casteggio is a comune (municipality) in the Province of Pavia in the Italian region Lombardy, located about 61 km south of Milan and about 25 km south of Pavia. As of 31 July 2010, it had a population of 6,537 and an area of 17.8 km².
Casteggio borders the following municipalities: Borgo Priolo, Calvignano, Casatisma, Corvino San Quirico, Montebello della Battaglia, Oliva Gessi, Robecco Pavese, Verretto.

## History

Clastidium was a settlement of the Ligures, belonging to the tribe called Marici by the Romans (and wrongly identified as Celts by Polybius). The location was the site of a major defeat of the Marici by the legions of Marcus Claudius Marcellus, which was celebrated in a tragedy by the Latin poet Naevius. In 218 BC it regained its independence after the Roman defeat in the neighbourhood by Hannibal's army; however it fell again to Roman rule in 197 BC, when it was also set to fire.
Never to recover its former splendour, it was annexed to the colonia of Piacenza, and remained under that city’s control after the fall of the Western Roman Empire.
In the Middle Ages Casteggio came under the influence of Pavia, to which it was assigned by Frederick Barbarossa in 1164. In 1441 it was acquired by Cesare Martinengo, and was later ruled by the Simonetta, Sforza, Bentivoglio and Del Carretto dynasties. It was heavily damaged during the Italian Wars of late 15th and early 16th centuries.

## Notable people

* Birthplace of the explorer Giuseppe Maria Giulietti.
# Casteddu di Tappa

Casteddu di Tappa is a Bronze Age archaeological site of the Torreann Culture, in Corsica. It is located in the commune of Porto-Vecchio.
# Avobenzone (data page)

The complete data for Avobenzone (v) :
* Database data |
* SMILES: CC(C)(C)C1=CC=C(C=C1)C(=O)CC(=O)C2=CC=C(C=C2)OC InChI=1/C20H22O3/c1-20(2,3)16-9-5-14(6-10-16)18(21)13-19(22)15-7-11-17(23-4)12-8-15/h5-12H,13H2,1-4H3  ATC: N/A CAS: [70356-09-1] DrugBank: N/A EINECS: 274-581-6  PubChem: 51040 |
* Physical properties |
* Structure Crystal data Spectral dataUV-Vis IR NMR MSPhase behavior Solid properties ρ$_{solid}$: 1.037 g.cm$^{−3}$ T$_m$: 80 - 85 °C Liquid properties Gas properties |
* Hazard properties |
* MSDS N/AMain hazards:- N/ANFPA 704Flash point- N/ARTECS number: N/A |
* Chemical properties |
* XLogP: 5.162 pI: pK$_a$: Tautomers: 3 Hydrogen bond: donor - 0 ;  acceptor - 3 |
* Pharmacological properties |
* view
* Except where noted otherwise, data relate to Standard temperature and pressure.
* Reliability of data general note.
# Carter Stevens

Carter Stevens (October 17, 1944 – December 30, 2020) was a pornographic film actor, director, grip, gaffer, and film processing lab technician.
Stevens earned a degree in photography from the Rochester Institute of Technology, worked at Eastman Kodak Company and was a shift supervisor at Movielab, the largest independent motion picture processing facility in New York, before going into film-making. He made 8 mm loops, appeared in over 50 adult films between around 1973 and 1993, and directed about 40 films between 1972 and 1996, including a series of films for the Avon Theater chain.
After Stevens's film Punk Rock received favorable reviews and with the increasing popularity of the punk rock music genre, he re-edited and released the film into an R-rated version, replacing explicit sex footage with more music and expanded plot.
He fought battles with drugs, a life-threatening heart attack, and charges of obscenity before re-emerging in the 1990s and early 2000s to produce the BDSM-related S&M News, and several print publications.

## Awards

* 2004 Free Speech Coalition Lifetime Achievement Award - Director
* 2009 AVN Hall of Fame inductee
# The Summer I Turned Pretty

The Summer I Turned Pretty may refer to:
# 2008 European Canoe Slalom Championships

The 2008 European Canoe Slalom Championships took place at the Kraków-Kolna Canoe Slalom Course in Kraków, Poland between May 8 and 11, 2008 under the auspices of the European Canoe Association (ECA). It was the 9th edition. These championships also served as the Olympic qualification for the 2008 Summer Olympics.

## Medal summary
### Men's results
#### Canoe

| Event | Gold | Points | Silver | Points | Bronze | Points |
| C1 | Michal Martikán (SVK) | 186.91 | Stanislav Ježek (CZE) | 187.89 | Alexander Slafkovský (SVK) | 189.73 |
| C1 team | Slovakia Michal Martikán Alexander Slafkovský Matej Beňuš | 214.81 | Poland Krzysztof Bieryt Grzegorz Kiljanek Dawid Bartos | 218.56 | Germany Christian Bahmann Nico Bettge Lukas Hoffmann | 222.78 |
| C2 | Slovakia Pavol Hochschorner Peter Hochschorner | 198.76 | Slovakia Ladislav Škantár Peter Škantár | 207.00 | Italy Andrea Benetti Erik Masoero | 207.23 |
| C2 team | Germany Marcus Becker & Stefan Henze Kay Simon & Robby Simon David Schröder & Frank Henze | 251.09 | Poland Marcin Pochwała & Paweł Sarna Dominik Węglarz & Dawid Dobrowolski Dariusz Wrzosek & Jarosław Miczek | 254.95 | Slovakia Pavol Hochschorner & Peter Hochschorner Ladislav Škantár & Peter Škantár Tomáš Kučera & Ján Bátik | 257.75 |

#### Kayak

| Event | Gold | Points | Silver | Points | Bronze | Points |
| K1 | Campbell Walsh (GBR) | 181.63 | Daniele Molmenti (ITA) | 181.76 | Fabian Dörfler (GER) | 182.41 |
| K1 team | Poland Dariusz Popiela Grzegorz Polaczyk Mateusz Polaczyk | 204.76 | Italy Diego Paolini Daniele Molmenti Luca Costa | 207.28 | Switzerland Michael Kurt Mathias Röthenmund Moritz Lüscher | 209.11 |

### Women's results
#### Kayak

| Event | Gold | Points | Silver | Points | Bronze | Points |
| K1 | Štěpánka Hilgertová (CZE) | 200.89 | Marie Řihošková (CZE) | 201.50 | Irena Pavelková (CZE) | 203.97 |
| K1 team | Germany Claudia Bär Mandy Planert Jasmin Schornberg | 230.62 | Slovakia Jana Dukátová Elena Kaliská Gabriela Stacherová | 236.59 | United Kingdom Fiona Pennie Louise Donington Laura Blakeman | 253.44 |

## Medal table

| Rank | Nation | Gold | Silver | Bronze | Total |
| 1 | Slovakia (SVK) | 3 | 2 | 2 | 7 |
| 2 | Germany (GER) | 2 | 0 | 2 | 4 |
| 3 | Czech Republic (CZE) | 1 | 2 | 1 | 4 |
| 4 | Poland (POL) | 1 | 2 | 0 | 3 |
| 5 | Great Britain (GBR) | 1 | 0 | 1 | 2 |
| 6 | Italy (ITA) | 0 | 2 | 1 | 3 |
| 7 | Switzerland (SUI) | 0 | 0 | 1 | 1 |
| Totals (7 entries) | Totals (7 entries) | 8 | 8 | 8 | 24 |
# Catalonia Today

Catalonia Today is a monthly English-language magazine and website with news of Catalonia. It has been linked from the outset with El Punt Avui group, with whom it shares content.

## History and profile

The project began in 2004 as a free newspaper with the momentum of journalist and politician Carles Puigdemont, and the Barcelona correspondent of The Times, Stephen Burgen. By 2010 it had a circulation of 15,000 copies and more than 4,500 subscribers.
The idea of the project was to create a newspaper about Catalonia, but in English, in order to fill the void of the market in this respect, aimed at tourists and foreign residents living in Catalonia, as well as Catalans interested in reading and improving their English. Among the collaborators are Matthew Tree, Martin Kirby, Xevi Xirgo, Joan Ventura and Emma Ansola.
In 2010, it was awarded with the Francesc Macià Memorial Award by the Josep Irla Foundation for its defense of Catalan culture and nation.
Its editor (as of 2016) is Marcela Topor, wife of founder Carles Puigdemont.
# Ayuko Hatta

Ayuko Hatta (Japanese: 八田 鲇子, Hepburn: Hatta Ayuko, born May 30 (year unknown) in Hyōgo Prefecture) is a Japanese shōjo manga artist best known for Wolf Girl and Black Prince.

## Wolf Girl and Black Prince

オオカミ少女と黒王子 (Ōkami shōjo to kuro ōji) is Hatta's main work. It was serialised from 2011 to 2016 in Bessatsu Margaret magazine by publisher Shūeisha and collected in 16 tankōbon volumes. The series is about 17-year old Erika who tells her friends the lie that she is dating her attractive classmate Kyōya. She asks him to play along and pretend to be her boyfriend. Kyōya agrees but seizes the opportunity to be mean to her and boss her around. Soon, however, they fall in love with each other and become a genuine couple. The manga was adapted as an audio drama, anime television series and live-action film directed by Ryūichi Hiroki. The manga has been published in France by Kurokawa and in Germany by Kazé.

## Bye-bye Liberty

ばいばいリバティー (Bai bai ribatī) spans four volumes, making it Hatta's second-longest work to date. From 2016 to 2017 it also appeared in Bessatsu Margaret first. Like Wolf Girl and Black Prince, the story is about a schoolgirl and her male schoolmate who can't stand each other at first but eventually fall in love with each other. This time it is the girl, Rina or Lina, who at first has no interest in romance in general and the boy next door, Takumi, in particular. To fend off a bothersome female suitor, Takumi pretends to be Rina's boyfriend and kisses her. However, for Rina, Takumi is nothing more than an unlikable womanizer. Only by and by her attitude towards him begins to change. Bye-bye Liberty has been released in French by Kurokawa and in German by Kazé.

## Ima Koi: Now I'm in Love

Ima Koi: Now I'm in Love (今、恋をしています, Ima, koi o shite imasu, literally "I am in love now") is Hatta's latest manga. Its serialisation in Bessatsu Margaret began in 2019 and 7 tankōbon volumes have been published so far. Once more, the story is about conflicted feelings between a schoolgirl and a schoolboy.

## Selected other manga

* 灰原くんはご機嫌ななめ, Haibara-kun wa gokigen naname, 2018–2019
* ぐるぐるめぐる, Guru guru meguru, 2010
* 悪い子の味方, Warui ko no mikata, 2009
* キミを中心に世界はまわる, Kimi o chūshin ni sekai wa mawaru, 2009
* ボクの世界 キミのリアル, Boku no sekai kimi no riaru, 2008
* ひよこロマンチカ, Hiyoko romanchika, 2007
* オーダーは僕でよろしいですか？, Ōdā wa boku de yoroshii desu ka?, 2007
# Grandfather's Clock

Grandfather's Clock is an easy patience or solitaire card game using a deck of 52 playing cards. Its foundation is akin to Clock Patience; but while winning the latter depends entirely on the luck of the draw, Grandfather's Clock has a strategic side, with the chances of winning being around 3 out of 4 games, especially if careful consideration is given to which cards would be released in instances where you have a choice of plays between identical cards.

## Rules

Before the game begins, the following cards are taken out of the deck: 2♥, 3♠, 4♦, 5♣, 6♥, 7♠, 8♦, 9♣, 10♥, J♠, Q♦, K♣. They are then arranged in a circular fashion like a clock face with the 2♥ on the "five o' clock" position, 3♠ on the "six o' clock" position, and so on. These cards will be the foundations. The remaining cards are then shuffled and dealt into eight columns of five cards each on the tableau.
The object of the game is to distribute the cards to the foundations to the point that the top cards of the foundations show the correct numbers on the clock face. Queens are assigned a value of twelve, and Jacks a value of eleven.
Each foundation should be built up by suit until the card with the correct corresponding number on the clock face is placed. The cards on the tableau are built down regardless of suit. Only the top cards of each column are available for play. Only one card can be moved at a time and any space that occurs may be filled with any available card.
The game ends either with all cards are put into the foundations with the clock face showing the correct numbers, or when no cards in the tableau can be moved.

## Variations

Big Ben (sometimes called Clock) is a closely related game with similar game-play, but played with two decks.
# The Vyne Community School

The Vyne Community School is a coeducational community school in Basingstoke, England for young people aged 11–16, and still occupies the site of the former Queen Mary's School for Boys, in Vyne Road, Basingstoke. It is a specialist school for the Performing Arts.

## History

The school was created out of the merger of two pre-existing schools, Queen Mary's School for Boys, Basingstoke a selective grammar school, also known as QMSB, and Charles Chute Secondary Modern School, which occurred in 1970. Initially the school was known as Queen Mary's & Charles Chute School, and was the result of the U.K. Government's policy in the 1960s to make all maintained (state funded) schools comprehensive. In the first instance the school remained a single sex institution, becoming coeducational in 1971–72. The name "Queen Mary's" was later transferred to the Queen Mary's College, a Sixth Form College, in Cliddesden Road, Basingstoke. The school was thereupon renamed The Vyne School, in commemoration of the links that both schools had to The Vyne, a property owned by the National Trust for Places of Historic Interest or Natural Beauty, former home of the Sandys and Chute families, just north of Basingstoke.
In 1997 The School was used as a filming location in the LGBT Coming of age film Get Real (film)

## Facilities

The Vyne is the only school in Basingstoke to have a Combined Cadet Force (CCF).

## Notable alumni

* Kit Symons - Professional association football manager and former Welsh international footballer. Former manager of Crystal Palace, Colchester United and Fulham.
* Steve Hewlett - Professional ventriloquist and Britain's Got Talent finalist.
* Monty Don - British broadcaster and lead presenter of the BBC gardening television series Gardeners' World since 2003.
# Khasapur Dam

Khasapur Dam, is an earthfill dam on local river near Paranda, Osmanabad district in State of Maharashtra in India.

## Specifications

The height of the dam above lowest foundation is 23.78 m (78.0 ft) while the length is 1,882 m (6,175 ft). The gross storage capacity is 19,830.00 km$^3$ (4,757.47 cu mi).

## Purpose

* Irrigation
# Grammonota pictilis

Grammonota pictilis is a species of dwarf spider in the family Linyphiidae. It is found in the United States and Canada.