# 2021 Little Rock Challenger – Singles

Dudi Sela was the defending champion but chose not to defend his title.
Jack Sock won the title after defeating Emilio Gómez 7–5, 6–4 in the final.

## Seeds

* Jason Jung (quarterfinals)
* Michael Mmoh (withdrew)
* Emilio Gómez (final)
* Ernesto Escobedo (second round)
* Mitchell Krueger (semifinals)
* Thai-Son Kwiatkowski (quarterfinals)
* Roberto Cid Subervi (first round)
* Christopher Eubanks (second round)
* Peter Polansky (first round)

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Semifinals | Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final | Final |
| 5 | Mitchell Krueger | 4 | 6 | 3 | | | | |
| | Jack Sock | 6 | 1 | 6 | | | | |
| | Jack Sock | 6 | 1 | 6 | | Jack Sock | 7 | 6 |
| | | | | | 3 | Emilio Gómez | 5 | 4 |
| 3 | Emilio Gómez | 6 | 6 | | 3 | Emilio Gómez | 5 | 4 |
| | Gonçalo Oliveira | 4 | 2 | | | | | |

### Top half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 1 | J Jung | 6 | 6 | | | | | | | | | | | | | | | | |
| | C Harrison | 1 | 2 | | 1 | J Jung | 6 | 6 | | | | | | | | | | | |
| | N Jarry | 4 | 2 | | | H Moriya | 3 | 4 | | | | | | | | | | | |
| | H Moriya | 6 | 6 | | | | | | | 1 | J Jung | 6 | 2 | 1 | | | | | |
| | D King | 6 | 6 | | | | | | | 5 | M Krueger | 3 | 6 | 6 | | | | | |
| | TA Tirante | 4 | 4 | | | D King | 3 | 2 | | | | | | | | | | | |
| WC | Z Khan | 2 | 4 | | 5 | M Krueger | 6 | 6 | | | | | | | | | | | |
| 5 | M Krueger | 6 | 6 | | | | | | | | | | | | 5 | M Krueger | 4 | 6 | 3 |
| 4 | E Escobedo | 6 | 6 | | | | | | | | | | | | | J Sock | 6 | 1 | 6 |
| | D Young | 3 | 0 | | 4 | E Escobedo | 7$^9$ | 6$^9$ | 6$^5$ | | | | | | | | | | |
| | J Sock | 6 | 6 | | | J Sock | 6$^7$ | 7$^{11}$ | 7$^7$ | | | | | | | | | | |
| | R Quiroz | 3 | 1 | | | | | | | | J Sock | 6$^3$ | 7$^7$ | 6 | | | | | |
| | A Ritschard | 7$^7$ | 4 | 6 | | | | | | 6 | T-S Kwiatkowski | 7$^7$ | 6$^5$ | 4 | | | | | |
| | K King | 6$^5$ | 6 | 4 | | A Ritschard | 7 | 3 | 2 | | | | | | | | | | |
| Q | S Kozlov | 2 | 1 | | 6 | T-S Kwiatkowski | 5 | 6 | 6 | | | | | | | | | | |
| 6 | T-S Kwiatkowski | 6 | 6 | | | | | | | | | | | | | | | | |

### Bottom half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 8 | C Eubanks | 6 | 7$^7$ | | | | | | | | | | | | | | | |
| | N Mejía | 3 | 6$^3$ | | 8 | C Eubanks | 4 | 6$^4$ | | | | | | | | | | |
| | U Blanch | 5 | 6 | 6 | | U Blanch | 6 | 7$^7$ | | | | | | | | | | |
| Q | Z Svajda | 7 | 3 | 3 | | | | | | | U Blanch | 2 | 0 | | | | | |
| Q | A Galarneau | 6 | 6 | | | | | | | 3 | E Gómez | 6 | 6 | | | | | |
| | JC Aragone | 3 | 3 | | Q | A Galarneau | 4 | 4 | | | | | | | | | | |
| | A Velotti | 6$^2$ | 3 | | 3 | E Gómez | 6 | 6 | | | | | | | | | | |
| 3 | E Gómez | 7$^7$ | 6 | | | | | | | | | | | | 3 | E Gómez | 6 | 6 |
| 7 | R Cid Subervi | 3 | 4 | | | | | | | | | | | | | G Oliveira | 4 | 2 |
| | S Mukund | 6 | 6 | | | S Mukund | 6 | 4 | 2 | | | | | | | | | |
| | G Oliveira | 7 | 7$^8$ | | | G Oliveira | 4 | 6 | 6 | | | | | | | | | |
| WC | R Harrison | 5 | 6$^6$ | | | | | | | | G Oliveira | 1 | 7 | 2 | | | | |
| Q | D Kelly | 6 | 7 | | | | | | | WC | O Crawford | 6 | 5 | 0$^r$ | | | | |
| Alt | N Chappell | 1 | 5 | | Q | D Kelly | 4 | 1 | | | | | | | | | | |
| WC | O Crawford | 7 | 6 | | WC | O Crawford | 6 | 6 | | | | | | | | | | |
| 9 | P Polansky | 5 | 2 | | | | | | | | | | | | | | | |