# 2010 Internazionali Femminili di Palermo – Singles

Flavia Pennetta was the defending champion but lost to Kaia Kanepi in the final 6–4, 6–3.

## Seeds

* Flavia Pennetta (final)
* Aravane Rezaï (quarterfinals)
* Sara Errani (quarterfinals)
* Tsvetana Pironkova (second round)
* Kaia Kanepi (champion)
* Peng Shuai (withdrew due to left ankle injury)
* Arantxa Parra Santonja (first round)
* Julia Görges (semifinals)
* Alberta Brianti (second round)

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final | Final |
| 1/WC | Flavia Pennetta | 6 | 6 | | | | |
| 8 | Julia Görges | 0 | 4 | | | | |
| 8 | Julia Görges | 0 | 4 | 1/WC | Flavia Pennetta | 4 | 3 |
| | | | | 5 | Kaia Kanepi | 6 | 6 |
| 5 | Kaia Kanepi | 6 | 6 | 5 | Kaia Kanepi | 6 | 6 |
| WC | Romina Oprandi | 3 | 2 | | | | |

### Top half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 1/WC | F Pennetta | 6 | 6 | | | | | | | | | | | | | | |
| | K Wörle | 3 | 1 | | 1/WC | F Pennetta | 6 | 6 | | | | | | | | | |
| | J Kostanić Tošić | 0 | 3 | | | R Voráčová | 0 | 3 | | | | | | | | | |
| | R Voráčová | 6 | 6 | | | | | | | 1/WC | F Pennetta | 6 | 6 | | | | |
| Q | N Llagostera Vives | 6 | 3 | 6 | | | | | | Q | N Llagostera Vives | 4 | 2 | | | | |
| | A-L Grönefeld | 4 | 6 | 1 | Q | N Llagostera Vives | 7 | 6 | | | | | | | | | |
| | A Rus | 6$^0$ | 2 | | 9 | A Brianti | 6$^2$ | 2 | | | | | | | | | |
| 9 | A Brianti | 7 | 6 | | | | | | | | | | | 1/WC | F Pennetta | 6 | 6 |
| 4 | T Pironkova | 6 | 7 | | | | | | | | | | | 8 | J Görges | 0 | 4 |
| WC | A Floris | 4 | 6$^4$ | | 4 | T Pironkova | 6 | 2 | 2 | | | | | | | | |
| | J Craybas | 7 | 7 | | | J Craybas | 2 | 6 | 6 | | | | | | | | |
| | A Amanmuradova | 6$^{10}$ | 5 | | | | | | | | J Craybas | 2 | 4 | | | | |
| | ME Camerin | 2 | 3 | | | | | | | 8 | J Görges | 6 | 6 | | | | |
| Q | C Dentoni | 6 | 6 | | Q | C Dentoni | 4 | 3 | | | | | | | | | |
| Q | M Caregaro | 3 | 2 | | 8 | J Görges | 6 | 6 | | | | | | | | | |
| 8 | J Görges | 6 | 6 | | | | | | | | | | | | | | |

### Bottom half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 5 | K Kanepi | 7 | 6 | | | | | | | | | | | | | |
| | R de los Ríos | 5 | 4 | | 5 | K Kanepi | 6 | 6 | | | | | | | | |
| | IR Olaru | 6 | 6 | | | IR Olaru | 1 | 2 | | | | | | | | |
| LL | A Pivovarova | 4 | 3 | | | | | | 5 | K Kanepi | 6 | 6 | | | | |
| Q | M Lučić | 7 | 0 | 7 | | | | | 3 | S Errani | 2 | 2 | | | | |
| | P Parmentier | 5 | 6 | 6$^7$ | Q | M Lučić | 0 | 6$^4$ | | | | | | | | |
| | M Koryttseva | 2 | 3 | | 3 | S Errani | 6 | 7 | | | | | | | | |
| 3 | S Errani | 6 | 6 | | | | | | | | | | 5 | K Kanepi | 6 | 6 |
| 7 | A Parra Santonja | 5 | 3 | | | | | | | | | | WC | R Oprandi | 3 | 2 |
| | M Zec Peškirič | 7 | 6 | | | M Zec Peškirič | 4 | 5 | | | | | | | | |
| WC | R Oprandi | 5 | | | WC | R Oprandi | 6 | 7 | | | | | | | | |
| | K Šprem | 1 | r | | | | | | WC | R Oprandi | 7 | 6 | | | | |
| | Z Kučová | 4 | 0 | | | | | | 2 | A Rezaï | 5 | 0 | | | | |
| | M Duque Mariño | 6 | 6 | | | M Duque Mariño | 6$^3$ | 3 | | | | | | | | |
| | S Halep | 5 | 6 | 2 | 2 | A Rezaï | 7 | 6 | | | | | | | | |
| 2 | A Rezaï | 7 | 4 | 6 | | | | | | | | | | | | |