# List of number-one singles of 2021 (Spain)

This lists the singles that reached number one on the Spanish PROMUSICAE sales and airplay charts in 2021. Total sales correspond to the data sent by regular contributors to sales volumes and by digital distributors.

## Chart history

| Week | Issue date | Top Streaming, Downloads & Physical Sales | Top Streaming, Downloads & Physical Sales | Top Streaming, Downloads & Physical Sales | Most Airplay | Most Airplay | Most Airplay |
| Week | Issue date | Artist(s) | Song | Ref. | Artist(s) | Song | Ref. |
| 1 | January 1 | Bad Bunny and Jhay Cortez | "Dakiti" | | BTS | "Dynamite" | |
| 2 | January 8 | Bad Bunny and Jhay Cortez | "Dakiti" | | Nil Moliner | "Mi Religión" | |
| 3 | January 15 | Myke Towers and Juhn | "Bandido" | | Dani Martín | "Portales" | |
| 4 | January 22 | Myke Towers and Juhn | "Bandido" | | Ana Mena and Rocco Hunt | "A un paso de la luna" | |
| 5 | January 29 | Myke Towers and Juhn | "Bandido" | | Nil Moliner | "Mi Religión" | |
| 6 | February 5 | Myke Towers and Juhn | "Bandido" | | Nil Moliner | "Mi Religión" | |
| 7 | February 12 | Rochy RD, Myke Towers and Nicki Nicole | "Ella No Es Tuya" | | Camilo | "Vida De Rico" | |
| 8 | February 19 | Rochy RD, Myke Towers and Nicki Nicole | "Ella No Es Tuya" | | Nil Moliner | "Mi Religión" | |
| 9 | February 26 | C. Tangana featuring Gipsy Kings | "Ingobernable" | | Ana Mena and Rocco Hunt | "A un paso de la luna" | |
| 10 | March 5 | Rochy RD, Myke Towers and Nicki Nicole | "Ella No es Tuya" | | Camilo | "Vida De Rico" | |
| 11 | March 12 | Rochy RD, Myke Towers and Nicki Nicole | "Ella No es Tuya" | | Purple Disco Machine and Sophie and the Giants | "Hypnotized" | |
| 12 | March 19 | Rochy RD, Myke Towers and Nicki Nicole | "Ella No es Tuya" | | Purple Disco Machine and Sophie and the Giants | "Hypnotized" | |
| 13 | March 26 | Rochy RD, Myke Towers and Nicki Nicole | "Ella No es Tuya" | | Álvaro de Luna | "Juramento eterno de sal" | |
| 14 | April 2 | Los Legendarios, Wisin and Jhay Cortez | "Fiel" | | Beret and Melendi | "Desde Cero" | |
| 15 | April 9 | Los Legendarios, Wisin and Jhay Cortez | "Fiel" | | Purple Disco Machine and Sophie and the Giants | "Hypnotized" | |
| 16 | April 16 | Los Legendarios, Wisin and Jhay Cortez | "Fiel" | | Álvaro de Luna | "Juramento eterno de sal" | |
| 17 | April 23 | Sebastián Yatra featuring Myke Towers | "Pareja del Año" | | Purple Disco Machine and Sophie and the Giants | "Hypnotized" | |
| 18 | April 30 | Sebastián Yatra featuring Myke Towers | "Pareja del Año" | | Álvaro de Luna | "Juramento eterno de sal" | |
| 19 | May 7 | Sebastián Yatra featuring Myke Towers | "Pareja del Año" | | Álvaro de Luna | "Juramento eterno de sal" | |
| 20 | May 14 | Sebastián Yatra featuring Myke Towers | "Pareja del Año" | | Álvaro de Luna | "Juramento eterno de sal" | |
| 21 | May 21 | Rauw Alejandro | "Todo de Ti" | | Álvaro de Luna | "Juramento eterno de sal" | |
| 22 | May 28 | Rauw Alejandro | "Todo de Ti" | | Álvaro de Luna | "Juramento eterno de sal" | |
| 23 | June 5 | Rauw Alejandro | "Todo de Ti" | | Álvaro de Luna | "Juramento eterno de sal" | |
| 24 | June 12 | Rauw Alejandro | "Todo de Ti" | | Álvaro de Luna | "Juramento eterno de sal" | |
| 25 | June 19 | Rauw Alejandro | "Todo de Ti" | | Álvaro de Luna | "Juramento eterno de sal" | |
| 26 | June 26 | Rauw Alejandro | "Todo de Ti" | | Purple Disco Machine and Sophie and the Giants | "Hypnotized" | |
| 27 | July 3 | Rauw Alejandro | "Todo de Ti" | | Rauw Alejandro | "Todo de Ti" | |
| 28 | July 10 | Rauw Alejandro | "Todo de Ti" | | Álvaro de Luna | "Juramento eterno de sal" | |
| 29 | July 17 | Rauw Alejandro | "Todo de Ti" | | Álvaro de Luna | "Juramento eterno de sal" | |
| 30 | July 24 | Farruko | "Pepas" | | Rauw Alejandro | "Todo de Ti" | |
| 31 | July 31 | Farruko | "Pepas" | | Rauw Alejandro | "Todo de Ti" | |
| 32 | August 7 | Farruko | "Pepas" | | Rauw Alejandro | "Todo de Ti" | |
| 33 | August 14 | Farruko | "Pepas" | | Rauw Alejandro | "Todo de Ti" | |
| 34 | August 21 | Farruko | "Pepas" | | Rauw Alejandro | "Todo de Ti" | |
| 35 | August 28 | Zzoilo and Aitana | "Mon Amour (Remix)" | | Rauw Alejandro | "Todo de Ti" | |
| 36 | September 4 | Zzoilo and Aitana | "Mon Amour (Remix)" | | Rauw Alejandro | "Todo de Ti" | |
| 37 | September 11 | Zzoilo and Aitana | "Mon Amour (Remix)" | | Rauw Alejandro | "Todo de Ti" | |
| 38 | September 18 | Zzoilo and Aitana | "Mon Amour (Remix)" | | Rauw Alejandro | "Todo de Ti" | |
| 39 | September 25 | Zzoilo and Aitana | "Mon Amour (Remix)" | | Rauw Alejandro | "Todo de Ti" | |
| 40 | October 2 | Zzoilo and Aitana | "Mon Amour (Remix)" | | Måneskin | "Beggin'" | |
| 41 | October 9 | C. Tangana and Nathy Peluso | "Ateo" | | Zzoilo and Aitana | "Mon Amour (Remix)" | |
| 42 | October 16 | C. Tangana and Nathy Peluso | "Ateo" | | Nil Moliner | "Libertad" | |
| 43 | October 23 | C. Tangana and Nathy Peluso | "Ateo" | | Nil Moliner | "Libertad" | |
| 44 | October 30 | C. Tangana and Nathy Peluso | "Ateo" | | Nil Moliner | "Libertad" | |
| 45 | November 6 | C. Tangana and Nathy Peluso | "Ateo" | | Nil Moliner | "Libertad" | |
| 46 | November 13 | Rosalía featuring The Weeknd | "La Fama" | | Zzoilo and Aitana | "Mon Amour (Remix)" | |
| 47 | November 20 | Rosalía featuring The Weeknd | "La Fama" | | The Kid Laroi and Justin Bieber | "Stay" | |
| 48 | November 27 | Rosalía featuring The Weeknd | "La Fama" | | Adele | "Easy on Me" | |
| 49 | December 3 | Zzoilo and Aitana | "Mon Amour (Remix)" | | Elton John and Dua Lipa | "Cold Heart" | |
| 50 | December 10 | Bizarrap and Morad | "Morad: Bzrp Music Sessions, Vol. 47" | | Adele | "Easy on Me" | |
| 51 | December 17 | Bizarrap and Morad | "Morad: Bzrp Music Sessions, Vol. 47" | | Adele | "Easy on Me" | |
| 52 | December 24 | Zzoilo and Aitana | "Mon Amour (Remix)" | | Adele | "Easy on Me" | |
| 1 | December 31 | Morad | "Pelele" | | Adele | "Easy on Me" | |