OpenLLM-France/wikimedia huggingface dataset:
# Ibandronic acid

Ibandronic acid is a bisphosphonate medication used in the prevention and treatment of osteoporosis and metastasis-associated skeletal fractures in people with cancer. It may also be used to treat hypercalcemia (elevated blood calcium levels). It is typically formulated as its sodium salt ibandronate sodium.
It was patented in 1986 by Boehringer Mannheim and approved for medical use in 1996.

## Medical uses

Ibandronate is indicated for the treatment and prevention of osteoporosis in post-menopausal women. In May 2003, the US Food and Drug Administration (FDA) approved ibandronate as a daily treatment for post-menopausal osteoporosis. The basis for this approval was a three-year, randomized, double-blind, placebo-controlled trial women with post-menopausal osteoporosis. Each participant also received daily oral doses of calcium and 400IUs [international units] of vitamin D. At the study's conclusion, both doses significantly reduced the occurrence risk of new vertebral fractures by 50–52 percent when compared to the effects of the placebo drug.
Ibandronate is efficacious for the prevention of metastasis-related bone fractures in multiple myeloma, breast cancer, and certain other cancers.

## Adverse effects

In 2008, the US Food and Drug Administration (FDA) issued a communication warning of the possibility of severe and sometimes incapacitating bone, joint or muscle pain. A study conducted by the American Society of Bone and Mineral Research concluded that long-term use of bisphosphonates, including Boniva, may increase the risk of a rare but serious fracture of the femur. The drug also has been associated with osteonecrosis of the jaw, a relatively rare but serious condition.

## Pharmacology
### Mechanism of action

Nitrogen containing bisphosphonates, which include ibandronate, pamidronate and alendronate exert their effects on osteoclasts mainly by inhibiting the synthesis of isoprenoid lipids such as isopentenyl diphosphate (IPP), farnesyl diphosphate (FPP), and geranylgeranyl diphosphate (GGPP) via the mevalonate pathway. These isoprenoids are used in posttranslational modifcation(prenylation) of small GTPases such as Ras, Rho, and Rac. These prenylated GTPases are necessary for various cellular processes including osteoclast morphology, endosome trafficking, and apoptosis.
Relative potency :
| Bisphosphonate | Relative potency |
| Etidronate | 1 |
| Tiludronate | 10 |
| Pamidronate | 100 |
| Alendronate | 100-500 |
| Ibandronate | 500-1000 |
| Risedronate | 1000 |
| Zoledronate | 5000 |

## Society and culture
### Brand names

Ibandronic acid is sold under the brand names Boniva, Bondronat, Bonviva, Bandrone, Ibandrix, Adronil, Bondrova, Bonprove, and Fosfonat.
# James G. Rowe Jr.

James Gordon Rowe Jr. (June 16, 1889 – October 21, 1931) was an American Thoroughbred horse trainer.

## Biography

The son of U.S. Hall of Fame trainer James G. Rowe Sr., he initially planned to become a mechanical engineer and graduated from Fordham and Cornell universities. However, in 1913 he went to work for his father as an assistant and later became an assistant to Scott Harlan at Helen Hay Whitney's Greentree Stable where by the mid-1920s he had several horses under his exclusive conditioning. In 1929, he took over from his father as head trainer for Harry Payne Whitney's Brookdale Farm. After Whitney died, James Rowe Jr. returned to work for Greentree Stable in the latter part of 1930, replacing Thomas W. Murphy.

## Triple Crown wins

Rowe Jr. won all three of the U.S. Triple Crown races. He trained the 1928 Preakness Stakes winner Victorian, and in 1929 was the Leading trainer in the United States by earnings with $314,881 in purse money.
Rowe Jr.'s most famous horse was the Hall of Fame inductee Twenty Grand with which he won the other two Triple Crown races in 1931 and earned American Horse of the Year honors. Twenty Grand won the Kentucky Derby, was second in the Preakness which was run before the Derby that year, and won the Belmont Stakes. Rowe Jr. lived for only a few months after these victories, dying at age 42 of a heart attack in October of that year. He was buried next to his father in Red Bank, New Jersey. One of five children, his brother, Belmont A. Rowe, who was also involved in horse racing, died at a young age in 1927.
# War-time Refugees Removal Act 1949

The War-time Refugees Removal Act 1949 was a piece of Australian legislation that formed part of the White Australia policy. It was introduced by the Chifley government in July 1949, in order to give the federal government the explicit authority to deport non-white foreigners who had arrived in Australia during World War II.
The act was created in response to O'Keefe v Calwell (1948), a High Court decision that found in favour of an Indonesian woman, Annie O'Keefe, who had been issued a deportation order under the Aliens Deportation Act 1948. The Minister for Immigration, Arthur Calwell, was a strong supporter of the White Australia policy, and claimed that the High Court's decision would lead to a "mongrel Australia". The government wished to expel the 800 or so foreign non-whites who had entered Australia during World War II, and formulated a new act to eliminate the loopholes that the High Court case had uncovered. The new act, which came into force in July 1949, "empowered the minister to force any person to depart the country who had been allowed to enter as a result of the war and had not since left". Calwell made extensive use of his new powers up until the December 1949 federal election, where the Labor government was defeated. Harold Holt, the immigration minister in the incoming Menzies government, opposed the White Australia policy and declined to make use of the act's provisions, accepting the refugees as a "wartime legacy". His successors did the same, and the act was eventually formally repealed by the Statute Law Revision Act 1973.
# Aleksandr Medved

Aleksandr Vasilyevich Medved (16 September 1937 – 2 September 2024) was a Ukrainian-born Soviet Belarusian freestyle wrestler of Russian ethnicity who competed for the Soviet Union and was named "one of the greatest wrestlers in history" by FILA, the sport's governing body. Between 1962 and 1972 he won three Olympic gold medals, seven world and three European titles. He served as the Olympic flag bearer for the Soviet Union in 1972, for Belarus in 2004 and recited the Judge's Oath at the Opening Ceremony of the 1980 Olympics.

## Biography

According to Medved, his grandparents came from Russia; his grandmother was ca. 195 cm, and his grandfather was even taller. Medved was smaller, at 190 cm and 100+ kg, yet big enough to fit into his last name, which means bear in Russian (and with minor variations in Belarusian and Ukrainian languages).
Between 1967 and 1972 Medved had a rivalry with Turkish-Bulgarian wrestler Osman Duraliev. They met eight times in the finals of major international championships and Medved won on all occasions. He was close to losing at the 1971 World Championships in Sofia, where Duraliev led the match 4:3 with 43 seconds left. Yet Medved equalized the score and won the title because of his lower body weight.
After retiring from competitions in 1972 Medved moved to Belarus, where prior he served with the Soviet Army in the late 1950s. There he worked as a national coach and lectured at the Belarusian State University of Informatics and Radioelectronics. After the dissolution of the Soviet Union he was appointed as vice-president of the Belarus Olympic Committee and of the Belarus Wrestling Federation. Previously he was awarded the Order of Lenin (1964), Order of the Red Banner of Labour (1970), and Order of the Badge of Honour (1964, 1969, 1985). In 2001 he was chosen as the best Belarusian athlete of the 20th century and in 2003 became one of the first 10 inductees to the FILA International Wrestling Hall of Fame. He is an honored citizen of Minsk, where since 1970s an annual wrestling tournament is held in his honor.
Medved was married to Tatyana, they had a daughter Yelena and son Aleksei. Yelena was a Belarusian tennis champion, while Aleksei won a junior world title in wrestling in 1987.
Medved died in Minsk on 2 September 2024, at the age of 86.
# Ľuboš Benkovský

Ľuboš Benkovský (born 22 February 1989) is a Slovak professional football manager and a former player, who last managed ViOn Zlaté Moravce in the Fortuna Liga.
# Sulaimon

Sulaimon is both a given name and a surname. Notable people with the name include:
* Sulaimon Adekunle (born 1990), Nigerian footballer
* Sulaimon Runsewe (born 2001), Nigerian cricketer
* Rasheed Sulaimon (born 1994), American-Nigerian basketball player
* Adeniyi Sulaimon Gbadegesin (born 1958), Nigerian academic
* Yusuf Sulaimon Lasun (born 1960), Nigerian politician
# Craig Considine

Craig Anthony Considine (born 18 June 1959) is a former Australian rules footballer who played with Richmond in the Victorian Football League (VFL).
He also competed in the decathlon representing Australia at the 1978 Commonwealth Games.
# FV-100

FV-100, also known as Cf1743, is an orally available nucleoside analogue drug with antiviral activity. It may be effective against shingles.
It was discovered in 1999 in the laboratories of Prof Chris McGuigan, Welsh School of Pharmacy and Prof. Jan Balzarini, Rega Institute, Leuven, Belgium.

## Clinical trials

FV-100 was tested against valaciclovir in a phase II trial in patients with herpes zoster. The trial was sponsored by Bristol-Myers Squibb. The drug is currently being developed by ContraVir Pharmaceuticals, Inc., Edison, New Jersey. It has reached Phase III clinical trials.
# Ernest Edward Greene House

The Ernest Edward Greene House is a historic residence in Cullman, Alabama, United States. The house was built in 1913 by Ernest Edward Greene, the superintendent of Southern Cotton Oil Company. After Greene's death in 1922, the house was passed on to several more owners, including John George Luyben, Sr., who lived in the house for 34 years.
The two-story house is built in Neoclassical style, and has a side gable roof with two interior chimneys. The three-bay façade features a double-height portico, supported by two Ionic columns. The corners of the house have matching Ionic capitaled pilasters. A one-story, hip roofed porch supported by ten Tuscan columns wraps around the front of the house and halfway down each side. The front door has one large pane of glass, as well as a transom and sidelights; a similar door leads from the second floor hall to the deck above. The door and portico are flanked on the first floor by 40-over-1 sash windows on the ground floor, while the second floor features 35-over-1 sashes; the side elevations have 25-over-1 sashes, with 20-over-1 and 10-over-1 windows on the rear. There are rounded 25-over-1 windows in the attic-level gable ends. The interior is laid out in a center-hall plan, with two rooms on either side of a main hall. A dining room, living room, kitchen, and study are on the main floor, with three bedrooms and a sitting room on the second.
The house was listed on the Alabama Register of Landmarks and Heritage in 1986 and the National Register of Historic Places in 1993.
# Aplasia cutis congenita

Aplasia cutis congenita is a rare disorder characterized by congenital absence of skin. Ilona J. Frieden classified ACC in 1986 into 9 groups on the basis of location of the lesions and associated congenital anomalies. The scalp is the most commonly involved area with lesser involvement of trunk and extremities. Frieden classified ACC with fetus papyraceus as type 5. This type presents as truncal ACC with symmetrical absence of skin in stellate or butterfly pattern with or without involvement of proximal limbs. It is the most common congenital cicatricial alopecia, and is a congenital focal absence of epidermis with or without evidence of other layers of the skin.
The exact etiology of ACC is still unclear but intrauterine infection by varicella or herpes virus, drugs such as methimazole, misoprostol, valproate, cocaine, marijuana etc., fetus papyraceus, feto-fetal transfusion, vascular coagulation defects, amniotic membrane adherence, abnormal elastic fiber biomechanical forces and trauma are implicated. It can be associated with Johanson–Blizzard syndrome, Adams–Oliver syndrome, trisomy 13, and Wolf–Hirschhorn syndrome. It can also be seen with exposure to methimazole and carbimazole in utero. This dermatological manifestation has been linked to Peptidase D haploinsufficiency and a deletion in Chromosome 19.

## Signs and symptoms

Review Edwards disease

## Genetics

This condition has been linked to mutations in the ribosomal GTPase BMS1 gene.

## Treatment

Skin grafting is a solution to fix aplasia cutis congenita.
# List of ships named Poseidon

Poseidon has been the name of a number of ships, both real and in fiction.

## Ships

* SS Poseidon was 1968–1969 the name of a steam cargo ship built in 1941 for the British Government and originally named Empire Ballard.
* BN Poseidon was 1951–1959 the name of a coastal tanker launched in 1942 as Empire Faun
* ST Poseidon was 1973–1976 the name of a steam tugboat built in 1941 for the British Government and originally named Empire Fir.
* HMS Poseidon was a Royal Navy Parthian-class submarine, launched in 1929 and sunk in 1931.
* USS Poseidon (ARL-12) was a United States Navy Achelous-class repair ship, built in 1944 and sold off in 1961.
* Greek submarine Poseidon (S-78), a Gato-class submarine
* KBV 001 Poseidon (IMO 9380441), a Swedish Coast Guard vessel

## In fiction

* SS Poseidon, the namesake ship in the novel The Poseidon Adventure and its adaptations
# Anatoli Klimenko

Anatoli Klimenko (born September 2, 1963 in Karaganda) is a Belarusian sport shooter. He competed in rifle shooting events at the 1996 and 2000 Summer Olympics.

## Olympic results

| Event | 1996 | 2000 |
| 50 meter rifle three positions (men) | T-28th | T-25th |
| 10 meter air rifle (men) | T-11th | 4th |
# Karol Rozmuš

Karol Rozmuš (born 18 April 1987) is a former Slovak slalom canoeist who competed at the international level from 2004 to 2014, specializing primarily in the C1 discipline.
He won a bronze medal in the C1 team event at the 2014 European Canoe Slalom Championships in Vienna. He also finished 22nd in the individual C1 event at the same championships. He finished 10th in the C1 overall World Cup standings in 2012.
He also won a silver medal in the C1 event at the 2009 European U23 Championships in Liptovský Mikuláš, finishing runner-up to his teammate Matej Beňuš.
# Marko Raguž

Marko Raguž (Croatian pronunciation:; born 10 June 1998) is an Austrian professional footballer who plays as a forward for Austria Wien and represents Austria internationally at youth level.

## Club career

Raguž made his Austrian Football First League debut for LASK on 3 March 2017 in a game against Wacker Innsbruck and scored on his debut. On 1 July 2022, Raguž will be transferred to Austria Wien of the Austrian Bundesliga.

## Personal life

Raguž's parents are from Novi Travnik in Bosnia and Herzegovina. He is eligible to play for Austria, Bosnia and Herzegovina and Croatia internationally.

## Career statistics

    As of match played 7 July 2022
Appearances and goals by club, season and competition :
| Club | Season | League | League | League | Cup | Cup | Europe | Europe | Other | Other | Total | Total |
| Club | Season | Division | Apps | Goals | Apps | Goals | Apps | Goals | Apps | Goals | Apps | Goals |
| LASK | 2016–17 | 2. Liga | 11 | 2 | 1 | 0 | — | — | — | — | 12 | 2 |
| LASK | 2017–18 | Austrian Bundesliga | 14 | 0 | 2 | 1 | — | — | — | — | 16 | 1 |
| LASK | 2018–19 | Austrian Bundesliga | 0 | 0 | 0 | 0 | — | — | — | — | 0 | 0 |
| LASK | 2019–20 | Austrian Bundesliga | 27 | 7 | 5 | 1 | 14 | 6 | — | — | 46 | 14 |
| LASK | 2020–21 | Austrian Bundesliga | 6 | 2 | 2 | 1 | 5 | 4 | — | — | 13 | 7 |
| LASK | 2021–22 | Austrian Bundesliga | 9 | 1 | 1 | 0 | 3 | 1 | — | — | 13 | 2 |
| LASK | Total | Total | 67 | 12 | 11 | 3 | 22 | 11 | 0 | 0 | 100 | 26 |
| Career total | Career total | Career total | 67 | 12 | 11 | 3 | 22 | 11 | 0 | 0 | 100 | 26 |
# Adriana Medveďová

Adriana Medveďová (born 11 July 1992) is a Slovak handballer who plays for the Slovakia national team.

## Achievements

* Czech–Slovak Interliga:
** Winner: 2013, 2014, 2015, 2016, 2017
# Luka Capan

Luka Capan (born 6 April 1995) is a Croatian professional footballer who plays as a centre-back for Serbian club TSC.

## Career

His first involvement with Dinamo Zagreb was being an unused substitute in an UEFA Europa League defeat to Ludogorets in December 2013. He was included in the squad following the injury of Jeremy Taravel. He made his debut for the club in a 6–1 win against Slaven Belupo in March 2014, coming as a 60th-minute substitute for Jozo Šimunović. In January 2018, Capan signed a three-and-a-half-year contract with HNK Rijeka.
In July 2023, Capan joined newly promoted Super League Greece club Kifisia.
In May 2024, Capan joined Serbian SuperLiga club TSC.

## Career statistics

    As of 8 August 2023
| Club | Season | League | League | League | Cup | Cup | Continental | Continental | Other | Other | Total | Total |
| Club | Season | Division | Apps | Goals | Apps | Goals | Apps | Goals | Apps | Goals | Apps | Goals |
| Dinamo Zagreb | 2013–14 | Prva HNL | 6 | 0 | 3 | 0 | 0 | 0 | — | — | 9 | 0 |
| Dinamo Zagreb | 2014–15 | Prva HNL | 0 | 0 | 0 | 0 | 0 | 0 | — | — | 0 | 0 |
| Dinamo Zagreb | Total | Total | 6 | 0 | 3 | 0 | 0 | 0 | — | — | 9 | 0 |
| Lokomotiva Zagreb | 2015–16 | Prva HNL | 26 | 1 | 1 | 0 | 4 | 0 | — | — | 31 | 1 |
| Lokomotiva Zagreb | 2016–17 | Prva HNL | 25 | 1 | 3 | 0 | 7 | 0 | — | — | 35 | 1 |
| Lokomotiva Zagreb | 2017–18 | Prva HNL | 14 | 4 | 2 | 0 | — | — | — | — | 16 | 4 |
| Lokomotiva Zagreb | Total | Total | 65 | 6 | 6 | 0 | 11 | 0 | — | — | 82 | 6 |
| Rijeka | 2017–18 | Prva HNL | 11 | 0 | 0 | 0 | — | — | — | — | 11 | 0 |
| Rijeka | 2018–19 | Prva HNL | 16 | 1 | 3 | 0 | 2 | 0 | — | — | 21 | 1 |
| Rijeka | 2019–20 | Prva HNL | 19 | 0 | 4 | 0 | 4 | 0 | — | — | 27 | 0 |
| Rijeka | 2020–21 | Prva HNL | 23 | 1 | 3 | 0 | 5 | 0 | — | — | 31 | 1 |
| Rijeka | Total | Total | 69 | 2 | 10 | 0 | 11 | 0 | — | — | 90 | 2 |
| Bursaspor | 2021–22 | TFF 1. Lig | 28 | 1 | 2 | 0 | — | — | — | — | 30 | 1 |
| Budapest Honvéd | 2022–23 | NB I | 18 | 0 | 1 | 0 | — | — | — | — | 19 | 0 |
| Career total | Career total | Career total | 186 | 9 | 22 | 0 | 22 | 0 | 0 | 0 | 230 | 9 |
# Hila, Idlib

Hila, Idlib (Arabic: حيلا) is a Syrian village located in Muhambal Nahiyah in Ariha District, Idlib. According to the Syria Central Bureau of Statistics (CBS), Hila, Idlib had a population of 860 in the 2004 census.
# Ictinia

Ictinia is a genus of birds in the family Accipitridae. It contains two species that are native to the Americas.

## Taxonomy and species

The genus Ictinia was introduced in 1816 by the French ornithologist Louis Pierre Vieillot to accommodate the plumbeous kite which is therefore the type species. The name is from the Ancient Greek word iktinos for a kite. The genus now contains two species.
Genus Ictinia – Vieillot, 1816 – two species :
| Common name | Scientific name and subspecies | Range | Size and ecology | IUCN status and estimated population |
| Mississippi kite | Ictinia mississippiensis (Wilson, A, 1811) | United States | Size: Habitat: Diet: | LC |
| Plumbeous kite | Ictinia plumbea (Gmelin, JF, 1788) | eastern Mexico to Peru, Bolivia and Argentina | Size: Habitat: Diet: | LC |
# John FitzPatrick, 1st Earl of Upper Ossory

John FitzPatrick, 1st Earl of Upper Ossory (1719 – 23 September 1758), styled Lord Gowran from 1727–51, was an Anglo-Irish nobleman and politician from County Cork, Ireland.

## Biography

Fitzpatrick was the son of Richard FitzPatrick, 1st Baron Gowran, and Anne (née Robinson) and was educated at Queen's College, Oxford.
He succeeded his father as 2nd Baron Gowran in 1727 and his mother to the estates of Farmingwoods (now Fermyn Woods), Northamptonshire and Ampthill, Bedfordshire in 1744. He was created Earl of Upper Ossory in the Irish peerage on 5 October 1751. He was MP for Bedfordshire from 1753–8.
He married Lady Evelyn Leveson-Gower, daughter of the 1st Earl Gower, on 29 June 1744. They had four children:
* John FitzPatrick, Lord Gowran, later 2nd Earl of Upper Ossory (1745–1818)
* The Hon. Richard FitzPatrick (24 January 1748 – 25 April 1813)
* The Lady Mary FitzPatrick (bef. 1751 – 6 October 1778), married the 2nd Baron Holland and had issue.
* The Lady Louisa FitzPatrick (1755 – 7 August 1789), married the 2nd Earl of Shelburne (later the 1st Marquess of Lansdowne) and had issue including Henry Petty-Fitzmaurice, 3rd Marquess of Lansdowne.
# Luzia Simão

Luzia Adão Simão (born 20 February 1992) is an Angolan basketball player. She competed for Angola at the 2011 FIBA Africa Championship. She is 5 ft 5 inches tall.
# Canton of Vincennes

The canton of Vincennes is an administrative division of the Val-de-Marne department, Île-de-France region, northern France. It was created at the French canton reorganisation which came into effect in March 2015. Its seat is in Vincennes.
It consists of the following communes:
* Saint-Mandé
* Vincennes (partly)
# Eva Minárčiková

Eva Minárčiková (born 3 July 1992) is a Slovak handball player for DHC Sokol Poruba and the Slovak national team.
# Billy the Kid Returns

Billy the Kid Returns is a 1938 American Western film directed by Joseph Kane and starring Roy Rogers.

## Plot

Following the shooting of Billy the Kid by his former friend Sheriff Pat Garrett, lookalike deputy sheriff Roy Rogers, assisted by travelling musical instrument salesman Frog Millhouse, takes his place to defend the honest settlers of Lincoln County, New Mexico, from evil ranchers.

## Cast

* Roy Rogers as Roy Rogers / Billy the Kid
* Smiley Burnette as Frog Millhouse
* Lynne Roberts as Ellen Moore
* Morgan Wallace as J. B. Morganson
* Fred Kohler as Matson
* Wade Boteler as Sheriff Pat Garrett
* Edwin Stanley as Nathaniel Moore
* Horace Murphy as Mr. Miller - Homesteader
* Joseph Crehan as U.S. Marshal Dave Conway
* Robert Emmett Keane as Mr. Page

## Soundtrack

* Roy Rogers – "Born to the Saddle" (Written by Eddie Cherkose)
* Roy Rogers – "Trail Blazin'" (Written by Eddie Cherkose)
* Roy Rogers – "Save a Smile for a Rainy Day" (Written by Sid Robin and Foy Willing)
* Smiley Burnette – "Sing a Little Song About Anything" (Written by Smiley Burnette)
* Roy Rogers – "When I Camped Under the Stars" (Written by Tim Spencer)
* Roy Rogers – "When the Sun is Setting on the Prairie" (Written by Eddie Cherkose and Alberto Colombo)
# British Columbia Highway 12

Highway 12, opened in 1953, is a connection from the Trans-Canada Highway at Lytton to the town of Lillooet, one of two road connections between the Thompson-Nicola and Squamish-Lillooet Regional Districts. The highway originally went all the way to a junction with Highway 97 at Lower Hat Creek, but when the Duffey Lake Road was paved in 1992, the section of Highway 12 from Lillooet to Highway 97 was renumbered 99. Highway 12 follows the east bank of the Fraser River on the western flank of the small Clear Range for 62 km (39 mi) from a junction with Highway 1 at Lytton to a junction with Highway 99 just across the river from the town of Lillooet.

## Major intersections

| Regional District | Location | km | mi | Destinations | Notes |
| Thompson-Nicola | Lytton | 0.00 | 0.00 | Highway 1 (TCH) – Cache Creek, Hope | Southern terminus |
| Squamish-Lillooet | Lillooet | 61.90 | 38.46 | Highway 99 – Whistler | Northern terminus |
| 1.000 mi = 1.609 km; 1.000 km = 0.621 mi ||||||