# Swimming at the 2022 World Aquatics Championships – Men's 4 × 100 metre medley relay

The Men's 4 × 100 metre medley relay competition at the 2022 World Aquatics Championships was held on 25 June 2022.

## Records

Prior to the competition, the existing world and championship records were as follows.
| World record | United States | 3:26.78 | Tokyo, Japan | 1 August 2021 |
| Competition record | United States | 3:27.28 | Rome, Italy | 2 August 2009 |

## Results
### Heats

The heats were started at 09:21.
| Rank | Heat | Lane | Nation | Swimmers | Time | Notes |
| 1 | 3 | 4 | United States | Hunter Armstrong (53.70) Nic Fink (59.57) Trenton Julian (51.35) Brooks Curry (48.29) | 3:32.91 | Q |
| 2 | 2 | 6 | France | Yohann Ndoye Brouard (53.12) Antoine Viquerat (1:00.42) Léon Marchand (52.09) Maxime Grousset (47.35) | 3:32.98 | Q |
| 3 | 3 | 5 | Italy | Thomas Ceccon (53.87) Nicolò Martinenghi (59.50) Piero Codia (51.71) Lorenzo Zazzeri (47.94) | 3:33.02 | Q |
| 4 | 2 | 5 | Australia | Mitchell Larkin (54.02) Zac Stubblety-Cook (1:00.18) Matthew Temple (51.20) Jack Cartwright (47.80) | 3:33.20 | Q |
| 5 | 2 | 4 | Great Britain | Luke Greenbank (54.28) James Wilby (59.47) Jacob Peters (51.91) Lewis Burras (47.90) | 3:33.56 | Q |
| 6 | 2 | 3 | China | Xu Jiayu (53.72) Qin Haiyang (59.37) Wang Changhao (51.94) Pan Zhanle (48.58) | 3:33.61 | Q |
| 7 | 3 | 2 | Germany | Ole Braunschweig (53.95) Lucas Matzerath (1:00.00) Jan Eric Friese (51.73) Rafael Miroslaw (48.30) | 3:33.98 | Q |
| 8 | 2 | 7 | Austria | Bernhard Reitshammer (53.99) Valentin Bayer (59.79) Simon Bucher (51.36) Heiko Gigler (47.92) | 3:34.06 | Q, NR |
| 9 | 3 | 3 | Japan | Ryosuke Irie (53.31) Ryuya Mura (1:00.08) Naoki Mizunuma (52.66) Katsuhiro Matsumoto (48.12) | 3:34.17 | |
| 10 | 2 | 8 | Brazil | Guilherme Basseto (54.81) João Gomes Júnior (59.50) Matheus Gonche (52.18) Luiz Gustavo Borges (48.17) | 3:34.66 | |
| 11 | 3 | 6 | Canada | Javier Acevedo (53.52) James Dergousoff (1:01.06) Joshua Liendo (51.26) Ruslan Gaziev (48.78) | 3:35.62 | |
| 12 | 1 | 4 | Spain | Hugo González (53.67) Carles Coll (1:01.10) Alberto Lozano (52.44) Sergio de Celis (48.89) | 3:36.10 | |
| 13 | 1 | 3 | South Korea | Lee Ju-ho (53.04) Moon Seung-woo (1:00.33) Cho Sung-jae (52.72) Hwang Sun-woo (49.19) | 3:36.28 | |
| 14 | 2 | 2 | Greece | Evangelos Makrygiannis (53.43) Konstantinos Meretsolias (1:00.17) Konstantinos Stamou (52.48) Dimitrios Markos (49.28) | 3:36.36 | |
| 15 | 2 | 9 | Chinese Taipei | Chuang Mu-lun (55.65) Cai Bing-rong (1:03.17) Wang Kuan-hung (53.39) Wang Hsing-hao (50.00) | 3:42.21 | |
| 16 | 2 | 1 | Vietnam | Trần Hưng Nguyên (58.53) Phạm Thanh Bảo (1:03.66) Hồ Nguyễn Duy Khoa (55.37) Hoàng Quý Phước (50.13) | 3:47.69 | |
| 17 | 3 | 9 | Paraguay | Charles Hockin (56.68) Renato Prono (1:04.35) Ben Hockin (54.75) Matheo Mateos (52.54) | 3:48.32 | |
| 18 | 3 | 0 | Thailand | Tonnam Kanteemool (57.41) Dulyawat Kaewsriyong (1:05.15) Navaphat Wongcharoen (53.80) Ratthawit Thammananthachote (53.69) | 3:50.05 | |
| | 1 | 5 | Hong Kong | Lau Shiu Yue (56.88) Adam Chillingworth Nicholas Lim Ian Ho | Disqualified | Disqualified |
| | 3 | 7 | Lithuania | Erikas Grigaitis (55.61) Andrius Šidlauskas Deividas Margevičius Danas Rapšys | Disqualified | Disqualified |
| | 2 | 0 | Israel | | Did not start | Did not start |
| | 3 | 1 | Singapore | | Did not start | Did not start |
| | 3 | 8 | Egypt | | Did not start | Did not start |

### Final

The final was held at 19:20.
| Rank | Lane | Nation | Swimmers | Time | Notes |
| | 3 | Italy | Thomas Ceccon (51.93) Nicolò Martinenghi (57.47) Federico Burdisso (50.63) Alessandro Miressi (47.48) | 3:27.51 | =ER |
| | 4 | United States | Ryan Murphy (52.51) Nic Fink (57.86) Michael Andrew (50.06) Ryan Held (47.36) | 3:27.79 | |
| | 2 | Great Britain | Luke Greenbank (53.81) James Wilby (58.82) James Guy (51.23) Tom Dean (47.45) | 3:31.31 | |
| 4 | 6 | Australia | Isaac Cooper (54.29) Zac Stubblety-Cook (59.88) Matthew Temple (50.75) Kyle Chalmers (46.89) | 3:31.81 | |
| 5 | 5 | France | Yohann Ndoye Brouard (53.08) Antoine Viquerat (1:00.34) Léon Marchand (51.50) Maxime Grousset (47.45) | 3:32.37 | |
| 6 | 1 | Germany | Ole Braunschweig (53.94) Lucas Matzerath (59.32) Jan Eric Friese (51.03) Rafael Miroslaw (48.34) | 3:32.63 | |
| 7 | 8 | Austria | Bernhard Reitshammer (54.38) Valentin Bayer (59.73) Simon Bucher (51.04) Heiko Gigler (47.65) | 3:32.80 | NR |
| 8 | 7 | China | Wang Shun (55.19) Qin Haiyang (59.44) Wang Changhao (51.38) Pan Zhanle (48.61) | 3:34.62 | |