OpenLLM-France/wikimedia huggingface dataset:
# Ciprofloxacin/dexamethasone

Ciprofloxacin/dexamethasone, sold under the brand name Ciprodex among others, is an antibiotic/steroid fixed-dose combination medication used for the treatment of ear infections. It contains ciprofloxacin, as the hydrochloride, a fluoroquinolone antibacterial; and dexamethasone, a corticosteroid. It is used as ear drops.
Ciprofloxacin, a fluoroquinolone antibiotic, has shown in vitro activity against many Gram-positive and Gram-negative bacteria including Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, and Pseudomonas aeruginosa. Dexamethasone acts as an anti-inflammatory corticosteroid. In 2022, it was the 286th most commonly prescribed medication in the United States, with more than 500,000 prescriptions.

## Medical uses

Ciprofloxacin/dexamethasone is indicated for use in the treatment of acute otitis media and acute otitis externa (swimmer's ear) in people aged six months of age and older.

## Mechanism of action

Ciprofloxacin functions as a bactericide by interfering with DNA gyrase, an enzyme with a key role in the synthesis of bacterial DNA. Dexamethasone is used in combination in order to aid in the reducing inflammatory responses that often accompany bacterial infection.

## Clinical trials

In clinical trials, the median time to cessation of ear pain in ciprofloxacin/dexamethasone was five days in a sample population of 909 participants. However, the clinical trial failed to demonstrate any significant benefit of using the combination of active ingredients in ciprofloxacin/dexamethasone over ciprofloxacin alone, in regards to ear pain. Ciprofloxacin/dexamethasone was superior to ciprofloxacin in regards to time to cessation of otorrhea.

### Phase I

The most reported adverse effects of phase I studies included headache, rhinitis, pain, dyspepsia, and dysmenorrhea. Investigators did not believe that any of these were directly treatment-related, as many of these events are considered symptoms or manifestations of the underlying illness.

### Phase II and III

Treatment-related adverse effects in AOE studies were determined in phase II and III trials. This includes ear pruritus, ear debris, superimposed ear infection, ear congestion, ear pain, and erythema. Similar effects were demonstrated in AOMT studies. Overall, ciprofloxacin/dexamethasone was determined as a safe and well-tolerated drug for the treatment of AOE and AOMT. The proposed dosage for all patients was also effective and safe. Cure rates for pediatrics were slightly higher than adults in AOE studies.

## Drug interactions

Drug interactions have not been studied with ciprofloxacin/dexamethasone.

## Commercialization

Ciprofloxacin/dexamethasone, owned by Alcon Laboratories, Inc., is protected by multiple patents and will be restricted from generic manufacturing until 2025.
In October 2015, Alcon sued Dr. Reddy's Laboratories (DLR) for allegedly infringing on patents for the combination. A judge in the UK upheld the Alcon patent.
# Jesse L. Beauchamp

Jesse L. Beauchamp (born 1942) is the Charles and Mary Ferkel Professor of Chemistry at the California Institute of Technology.

## Early life and education

* 1964 B.S. California Institute of Technology
* 1967 Ph.D. Harvard University

## Research interests

* Development of novel mass spectrometric techniques in biochemistry.

## Awards

In 1978 he received the ACS Award in Pure Chemistry from the American Chemical Society and in 1981 was elected to the National Academy of Sciences. In 1999 he received the Peter Debye Award in Physical Chemistry from the American Chemical Society and was again honored in 2003 with the Field and Franklin Award in Mass Spectrometry. In 2007 he received the Distinguished Contribution Award from the American Society for Mass Spectrometry for the original development and chemical applications of ion cyclotron resonance spectroscopy.

## Former students

* Charles A. Wight – President of Weber State University
* Frances Houle (1979) – Director of JCAP North
* Terry B. McMahon (1974) – Professor or chemistry at the University of Waterloo
* Peter B. Armentrout (1980) – Professor of chemistry at the University of Utah
* David Dearden (1989) – Chemistry and Biochemistry department chair at BYU
* Elaine Marzluff (1995) – Chemistry department chair at Grinnell College
# Smart Woman (1948 film)

Smart Woman is a 1948 American romantic drama film directed by Edward A. Blatt and starring Brian Aherne, Constance Bennett, and Barry Sullivan.

## Plot

When a grand jury becomes dissatisfied with the efforts of District Attorney Bradley Wayne (Otto Kruger), it requests a special prosecutor, Robert Larrimore (Brian Aherne).
Wayne, who is in league with crime boss Frank McCoy (Barry Sullivan), assigns Larrimore the difficult Johnson case. McCoy blackmails the best defense lawyer around, Paula Rogers (Constance Bennett), into defending Johnson. When Larrimore's assistant, Sam Corkle (James Gleason), tracks down a crucial witness intimidated into hiding, McCoy tells Rogers to plead her client guilty.
Afterward, Larrimore begins dating Rogers. The couple make it into the newspapers, in between stories of Larrimore's successes against the crime syndicate.
Larrimore's investigation points to a Dr. Jasper, the one man who can identify the shadowy head of the syndicate. When Jasper goes into hiding from both sides, McCoy pressures Rogers to spy on her boyfriend. She finds a telegram with valuable information, but does not pass it along the gangster.
Meanwhile, Larrimore gives the crooked district attorney an ultimatum: either betray his partner in crime or face an indictment in 24 hours. When an attack on Larrimore is foiled, Wayne summons McCoy and shows him the gun used to kill Jasper. He offers McCoy $100,000 to put his fingerprints on it and flee the country for a while, just until the pressure subsides. When McCoy refuses, Wayne grabs the gun and states he can shoot McCoy and plead self-defense. In the ensuing struggle, the gun goes off, killing Wayne. Mrs. Wayne (Selena Royle), eavesdropping from outside the room, faints. McCoy is arrested and charged with first degree murder.
Rogers very reluctantly defends McCoy, knowing him to be incapable of murder (if little else). The trial goes badly. Mrs. Wayne perjures herself on the witness stand to protect the family's reputation, and states that McCoy gunned down her husband in cold blood. As a desperate last resort, Rogers puts herself on the stand as a character witness. She reveals that she was once married to the defendant and concealed the fact to protect their son Rusty. Larrimore sees that Mrs. Wayne is visibly affected by the testimony, so he goes to see her later and has her re-enact the crime. He discovers she did not have her glasses on that night and, as a result, could not have seen what happened. He gets her to sign a statement to that effect. Larrimore then overcomes Rogers' desire to break up with him to shield him from the scandal, and the couple reconcile.

## Cast

* Brian Aherne as Robert Larrimore
* Constance Bennett as Paula Rogers
* Barry Sullivan as Frank McCoy
* Michael O'Shea as Johnny Simons
* James Gleason as Sam Corkle
* Otto Kruger as District Attorney Bradley Wayne
* Isobel Elsom as Mrs. Rogers
* Richard Lyon as Rusty Rogers
* Selena Royle as Mrs. Wayne
* Taylor Holmes as Dr. Jasper
* John Litel as Clark
* Nita Hunter as Patty Wayne
# Dąbrowy, Warmian-Masurian Voivodeship

Dąbrowy is a village in the administrative district of Gmina Rozogi, within Szczytno County, Warmian-Masurian Voivodeship, in northern Poland. It lies approximately 6 kilometres (4 mi) south of Rozogi, 30 km (19 mi) south-east of Szczytno, and 70 km (43 mi) south-east of the regional capital Olsztyn.
The village has a population of 1,300.
# Rupert of Laurenburg

Rupert (German: Ruprecht) was Vogt at Siegen and is one of the eldest known possible ancestors of the House of Nassau.

## Life

Rupert is mentioned at Siegen between 1079 and 1082 as the owner of parts of the lands of Lipporn/Laurenburg, and in a charter from 1079/89 as Vogt at Siegen. He was a vassal of the Electorate of Mainz. It is possible that Rupert was already Count of Laurenburg, but he isn't mentioned as such in any charter.
Perhaps Rupert was a son of Adelhart, who is mentioned in a charter from 1048 as Vogt at Haiger for the Abbey of Worms. Rupert was the father of Dudo of Laurenburg.
There are more persons known who, as owners of the lands of Lipporn/Laurenburg (and thus the predecessors of Rupert), probably also were his ancestors. The first is a certain Drutwin mentioned in 881 as a landowner in Prüm, and who is the oldest known possible ancestor of the House of Nassau.
# Andrés Ardila

Andrés Camilo Ardila Ordoñez (born 2 June 1999) is a Colombian cyclist, who currently rides for UCI Continental team Nu Colombia.

## Major results
### 2017

    National Junior Road Championships
       2nd Road race
       2nd Time trial

### 2018

    1st Stage 5 Vuelta al Tolima
    5th Overall Vuelta de la Juventud de Colombia

### 2019

    1st Overall Giro Ciclistico d'Italia
       1st Young rider classification
       1st Stages 4 & 5
    3rd Overall Vuelta de la Juventud de Colombia
       1st Stages 3 & 5

### 2021

    3rd Time trial, National Road Championships
# St Michael and All Angels Church, Mount Dinham, Exeter

St Michael and All Angels Church, on Mount Dinham in Exeter is an Anglican church in Devon, England. It is a Grade I listed building. The church is Anglo-Catholic in tradition. The building in is the early Gothic style and was built to the designs of Major Rohde Hawkins, 1867–68. The reredos is by W. D. Caroe, 1899.
Within the Parish of St David with St Michael and All Angels, the building towers above its surroundings, the spire exceeding the height of even the towers of Exeter Cathedral.

## History

The foundation stone was laid on 10 August 1865 and construction was largely financed by businessman and Oxford Movement supporter William Gibbs who came from a local family. The church was consecrated on 31 October 1868 by the Bishop of Fredericton.

## Organ

The first organ was installed in 1866 and was by William Hill & Son. This was replaced by an organ originally in St Jude's Church, Birmingham, dating from 1867 and built by Edward James Bossward. It was installed and much enlarged by Tim Trenchard in 2013. A specification of the organ can be found on the National Pipe Organ Register.
# Photo Marketing Association

The Photo Marketing Association International (PMA) International Convention and Trade Show was an annual imaging technology trade show conducted by PMA held in Las Vegas. Since 2012, the show has been branded as PMA@CES, reflecting its rescheduling to coincide with the Consumer Electronics Show, a major annual consumer electronics trade show also held in Las Vegas.
The PMA International Convention and Trade Show is frequently the occasion for the public introduction of important imaging products. The major competition for this trade show is Photokina, held in even-numbered years in Cologne, Germany.
In 2012, PMA announced it would launch an online community known as The Big Photo Show, with associated trade shows under that banner in the U.S. The first such show was held in Los Angeles in May 2013, with another scheduled for that city in May 2014. Unlike PMA@CES, which is restricted exclusively to trade visitors, The Big Photo Show is specifically intended for consumers.
PMA has seven member associations: Association of Imaging Executives, Digital Imaging Marketing Association, National Association of Photo Equipment Technicians, Photo Imaging Education Association, Professional Picture Framers Association PPFA, Professional School Photographers Association and Sports Photographers Association of America.

## Shows
### PMA and PMA@CES

| Year | Dates |
| 1979 | March 25 – March 28, Chicago |
| 1981 | Early April, Miami |
| 1982 | February 17 – February 21, Las Vegas |
| 1987 | February 2 – February 25, Chicago |
| 2000 | February 3 – February 6 |
| 2001 | February 11 – February 14, Orlando |
| 2002 | February 24 – February 27, Orlando |
| 2004 | February 12 – February 15 |
| 2005 | February 20 – February 23 |
| 2006 | February 26 – March 1 |
| 2007 | March 8 – March 11 |
| 2008 | January 31 – February 2 |
| 2009 | March 3 – March 5 |
| 2010 | February 21 – February 23 |
| 2012 | January 10 – January 13 |
| 2013 | January 8 – January 11 |
| 2014 | January 7 – January 10 |
| 2015 | January 6 – January 9 |

### The Big Photo Show

| Year | Dates |
| 2013 | May 4 – May 5 |
| 2014 | May 17 – May 18 |
# Martin Knoller

Martin Knoller (18 November 1725 – 24 July 1804) was an Austrian-Italian painter active in Italy who is remembered for his fresco work.

## Biography

Born in Steinach am Brenner near the Austrian city of Innsbruck, Knoller studied under Paul Troger and Michelangelo Unterberger in Salzburg and Vienna. Specializing in frescoes and altarpiece paintings, his first fresco, the Glory of St Stephen, was completed in 1754 at the parish church of Anras in East Tyrol.
In 1755, he arrived in Rome where he was influenced by Neoclassicism, after studying under Anton Raphael Mengs and Johann Joachim Winckelmann. Knoller was influenced by the work of Anton von Maron.
His works cover both Baroque and Rococo, the latter prevailing in his paintings rather than in his frescoes. His greatest patron was Karl Joseph von Firmian, the Imperial Governor of Lombardy under Maria Theresa who commissioned him to paint the Palazzo Firmian-Vigoni. From 1793, he taught at the Brera Academy of Fine Arts in Milan where he died on 24 July 1804, aged 78, in Milan. Among his pupils was Giuseppe Mazzola.

## Works

Frescoes:
* Anras Church, East Tyrol (1754)
* Karlskirche, Volders near Innsbruck (1765)
* Ettal Abbey near Oberammergau (1769)
* Neresheim Abbey (1770–1775)
* Gries bei Bozen Abbey (1772–1775)
* Palazzo Belgioioso, Milan (1781)
* Taxis Palais, Innsbruck (1785–1786)
Altarpieces:
* Karlkirche, Volders
* Servitenkirche, Innsbruck
* Parish church of Steinach am Brenner
* St George and the Dragon, Deutschhauskirche, Bolzano
# Powayan Assembly constituency

Powayan is one of the 403 constituencies of the Uttar Pradesh Legislative Assembly, India. It is a part of the Shahjahanpur district and one of the five assembly constituencies in the Shahjahanpur Lok Sabha constituency. First election in this assembly constituency was held in 1957 after the "DPACO (1956)" (delimitation order) was passed in 1956. After the "Delimitation of Parliamentary and Assembly Constituencies Order" was passed in 2008, the constituency was assigned identification number 134.

## Wards / Areas

Extent of Powayan Assembly constituency is KCs Khutar, Powayan, Banda, Nahil, Powayan NP & Khutar NP of Powayan Tehsil.

## Members of the Legislative Assembly

| # | Term | Name | Party | From | To | Days | Comments |
| 01 | 01st Vidhan Sabha | - | - | Mar-1952 | Mar-1957 | 1,849 | Constituency not in existence |
| 02 | 02nd Vidhan Sabha | Rajkumar Surendra Singh | Independent | Apr-1957 | Mar-1962 | 1,800 | - |
| 02 | 02nd Vidhan Sabha | Kamle | Independent | Apr-1957 | Mar-1962 | 1,800 | - |
| 03 | 03rd Vidhan Sabha | Raja Vikaram Shah | Independent | Mar-1962 | Mar-1967 | 1,828 | - |
| 04 | 04th Vidhan Sabha | K. Lal | Indian National Congress | Mar-1967 | Apr-1968 | 402 | - |
| 05 | 05th Vidhan Sabha | Kandhai | Indian National Congress | Feb-1969 | Mar-1974 | 1,832 | - |
| 06 | 06th Vidhan Sabha | Roop Ram | Indian National Congress | Mar-1974 | Apr-1977 | 1,153 | - |
| 07 | 07th Vidhan Sabha | Suraj Prasad | Janata Party | Jun-1977 | Feb-1980 | 969 | - |
| 08 | 08th Vidhan Sabha | Roop Ram | Indian National Congress (I) | Jun-1980 | Mar-1985 | 1,735 | - |
| 09 | 09th Vidhan Sabha | Chetram | Indian National Congress | Mar-1985 | Nov-1989 | 1,725 | - |
| 10 | 10th Vidhan Sabha | Chetram | Indian National Congress | Dec-1989 | Apr-1991 | 488 | - |
| 11 | 11th Vidhan Sabha | Net Ram | Bharatiya Janata Party | Jun-1991 | Dec-1992 | 533 | - |
| 12 | 12th Vidhan Sabha | Chetram | Indian National Congress | Dec-1993 | Oct-1995 | 693 | - |
| 13 | 13th Vidhan Sabha | Chetram | Indian National Congress | Oct-1996 | May-2002 | 1,967 | - |
| 14 | 14th Vidhan Sabha | Mithlesh Kumar | Independent | Feb-2002 | May-2007 | 1,902 | - |
| 15 | 15th Vidhan Sabha | Mithlesh Kumar | Samajwadi Party | May-2007 | Mar-2012 | 1,762 | - |
| 16 | 16th Vidhan Sabha | Sakuntla Devi | Samajwadi Party | Mar-2012 | Mar-2017 | - | - |
| 17 | 17th Vidhan Sabha | Chetram | Bharatiya Janata Party | Mar-2017 | Mar-2022 | | |
| 18 | 18th Vidhan Sabha | Chetram | Bharatiya Janata Party | Mar-2022 | Incumbent | - | |

## Election results
### 2017

2017 General Elections: Powayan :
| Party | Party | Candidate | Votes | % | ±% |
| | BJP | Chetram Pasi | 1,26635 | | − |

### 2012

2012 General Elections: Powayan :
| Party | Party | Candidate | Votes | % | ±% |
| | SP | Sakuntla Devi | 59,871 | 28.78 | − |
| | BSP | Arun Kumar Sagar | 50,973 | 24.5 | − |
| | INC | Chetram | 50,551 | 24.3 | − |
| | | Remainder 13 candidates | 46,665 | 22.42 | − |
| Majority | Majority | Majority | 8,898 | 4.28 | − |
| Turnout | Turnout | Turnout | 208,060 | 65.3 | − |
| | SP hold | SP hold | Swing | | |
# Banking Commission of the West African Monetary Union

The Banking Commission of the West African Monetary Union (French: Commission Bancaire de l'Union Monétaire Ouest Africaine, CB-UMOA) is a supranational bank supervisor established in 1990 and based in Abidjan, Ivory Coast. It is institutionally part of the Central Bank of West African States (French acronym BCEAO) and is the single banking supervisor for the eight countries of the West African Monetary Union (UMOA), namely Benin, Burkina Faso, Guinea Bissau, Ivory Coast, Mali, Niger, Senegal, and Togo.

## Overview

In 1989, BCEAO Governor Alassane Ouattara promoted the creation of a single banking supervisory authority for the entire West African Monetary Union, in a context of banking sector fragility in West Africa and widespread supervisory failure by the then-existing national banking commissions of the individual UMOA member states.
The Banking Commission was established by an international convention signed by the participating governments in Ouagadougou on 24 April 1990, complemented by a bilateral agreement between the BCEAO and Ivory Coast on 16 October 1990 to establish the Commission in Abidjan with appropriate privileges and immunities. The area remains far from a full banking union, however, since the financial burden of bank crisis management and resolution has remained at the national level. The Banking Commission's scope of authority, moreover, only covers the larger and/or cross-border banks, whether smaller local banks remain supervised by national authorities.
The governor of the BCEAO acts as chairman (French: Président) of the CB-UMOA, whose operations are led by a secretary-general (French: Secrétaire général) based in Abidjan.

## Leadership

The following individuals have held the position of Secretary-General of the CB-UMOA since its establishment:
* Djibril Sakho, October 1990 - October 1993
* Marcel Kodjo, October 1993 - September 1998
* Emmanuel Nana, September 1998 - February 2003
* Mamadou Diop, February 2003 - January 2007
* Eric Ekue, January 2007 - January 2009
* Charles Luanga Ki-Zerbo, January 2009 - January 2012
* Sanou Bolo, January 2012 - December 2014
* Sena Elda Kpotsra, January 2015 - December 2019
* Antoine Traore, since December 2019

## Supervised entities by country

* List of banks in Benin
* List of banks in Burkina Faso
* List of banks in Guinea-Bissau
* List of banks in Ivory Coast
* List of banks in Mali
* List of banks in Niger
* List of banks in Senegal
* List of banks in Togo
# Democratic National Salvation Front

The Democratic National Salvation Front (Romanian: Frontul Democrat al Salvării Naționale, FDSN) was a Romanian political party formed by former President Ion Iliescu and his supporters stemming from the National Salvation Front (FSN) on 7 April 1992. It was the result of the breakup of the previously ruling FSN during the early 1990s.
The smaller wing led by Petre Roman continued using the brand FSN. Unlike the Petre Roman wing of the FSN, which wanted faster economic reforms, the FDSN advocated for an socialist democracy and a slower pace of transition from the communist command economy to a social market economy. On 10 July 1993, the FDSN merged with the Romanian Socialist Democratic Party (PSDR), the Republican Party, and the Cooperative Party, creating the Party of Social Democracy in Romania (PDSR). In 2001, PDSR merged with PSDR to create the present-day Social Democratic Party (PSD).

## Election history
### Legislative elections

| Election | Chamber | Chamber | Chamber | Senate | Senate | Senate | Position | Aftermath |
| Election | Votes | % | Seats | Votes | % | Seats | Position | Aftermath |
| 1992 | 3,015,708 | 27.72 | 117 / 341 | 3,102,201 | 28.29 | 49 / 143 | 1st | FDSN/PDSR minority government (1992–1995) PDSR-PUNR-PRM-PSM coalition (1995-1996) |

### Presidential elections

| Election | Candidate | First round | First round | First round | Second round | Second round | Second round |
| Election | Candidate | Votes | Percentage | Position | Votes | Percentage | Position |
| 1992 | Ion Iliescu | 5,633,465 | 47.5 | 1st | 7,393,429 | 61.4 | 1st |
# Dąbrówka, Olsztyn County

Dąbrówka is a village in the administrative district of Gmina Świątki, within Olsztyn County, Warmian-Masurian Voivodeship, in northern Poland.
Before 1772 the area was part of Kingdom of Poland, and in 1772–1945 it belonged to Prussia and Germany (East Prussia).
# Adrian Cosma

Adrian Cosma (5 June 1950 – 1996) was a Romanian handball player who won the world title in 1974. He competed at the 1972, 1976 and 1980 Olympics and won one silver and two bronze medals. During his career he played 130 times for the national team and scored 250 goals.
# Diego Camargo

Diego Andrés Camargo Pineda (born 3 May 1998 in Tuta, Boyacá) is a Colombian professional road racing cyclist, who currently rides for UCI Continental team Petrolike.

## Major results
### 2020

    1st Overall Vuelta a Colombia
       1st Young rider classification
    1st Overall Vuelta de la Juventud de Colombia

### 2021

    2nd Time trial, National Road Championships

### 2022

    3rd Time trial, National Road Championships

### 2023

    3rd Time trial, National Road Championships
    9th Mont Ventoux Dénivelé Challenge

### 2024

    2nd Overall Vuelta a Colombia
    6th Overall Volta a Portugal

### Grand Tour general classification results timeline

| Grand Tour | 2021 | 2022 | 2023 |
| Giro d'Italia | — | 79 | — |
| Tour de France | — | — | — |
| Vuelta a España | 53 | — | 84 |
Legend :
| — | Did not compete |
| DNF | Did not finish |