OpenLLM-France/wikimedia huggingface dataset:
# MEFV

MEFV (Mediterranean fever) is a human gene that provides instructions for making a protein called pyrin (also known as marenostrin). Pyrin is produced in certain white blood cells (neutrophils, eosinophils and monocytes) that play a role in inflammation and in fighting infection. Inside these white blood cells, pyrin is found with the cytoskeleton, the structural framework that helps to define the shape, size, and movement of a cell. Pyrin's protein structure also allows it to interact with other molecules involved in fighting infection and in the inflammatory response.
Although pyrin's function is not fully understood, it likely assists in keeping the inflammation process under control. Research indicates that pyrin helps regulate inflammation by interacting with the cytoskeleton. Pyrin may direct the migration of white blood cells to sites of inflammation and stop or slow the inflammatory response when it is no longer needed.
The MEFV gene is located on the short (p) arm of chromosome 16 at position 13.3, from base pair 3,292,027 to 3,306,626.

## Related conditions

More than 80 MEFV mutations that cause familial Mediterranean fever have been identified. A few mutations delete small amounts of DNA from the MEFV gene, which can lead to an abnormally small protein. Most MEFV mutations, however, change one of the protein building blocks (amino acids) used to make pyrin. The most common mutation replaces the amino acid methionine with the amino acid valine at protein position 694 (written as Met694Val or M694V). Among people with familial Mediterranean fever, this particular mutation is also associated with an increased risk of developing amyloidosis, a complication in which abnormal protein deposits can lead to kidney failure. Some evidence suggests that another gene, called SAA1, can further modify the risk of developing amyloidosis among people with the M694V mutation.
MEFV mutations lead to reduced amounts of pyrin or a malformed pyrin protein that cannot function properly. As a result, pyrin cannot perform its presumed role in controlling inflammation, leading to an inappropriate or prolonged inflammatory response. Fever and inflammation in the abdomen, chest, joints, or skin are signs of familial Mediterranean fever. Pyrin forms an inflammasome which senses RhoA GTPases inactivation and subsequent kinases (PKN1 and PKN2) inactivation. These kinases phosphorylate two serine residues located in the linker encoded by MEFV exon 2, allowing proteins 14.3.3 to keep pyrin inflammasome in an inactive state. Mutations in these serine residues are responsible for Pyrin-Associated Autoinflammation with Neutrophilic Dermatosis (PAAND). Recently, it has been shown that pyrin dephosphorylation is sufficient to trigger inflammasome activation in familial Mediterranean fever patients. Furthermore, while the trigger of FMF flares remain unknown, steroid hormone catabolites (pregnanolone and etiocholanaolone) have been shown to activate the pyrin inflammasome, in vitro, by interacting with the B30.2 domain (coded by exon 10).
# Knight Cancer Institute

The OHSU Knight Cancer Institute (previously the OHSU Cancer Institute) is a research institute within Oregon Health & Science University. The National Cancer Institute (NCI) designated cancer center is led by director Tom Sellers. It is the only NCI-designated Comprehensive Cancer Center in the state of Oregon. The institute is named after Phil Knight and his wife, who donated over $600 million to the center; $100 million in 2008 and $500 million in 2013. The $500 million gift required a matching $500 million, which led to a $100 million donation by Columbia Sportswear chairwoman Gert Boyle in 2014.

## History

The institute was first designated as a NCI Designated Cancer Center in 1997 and was awarded the status of comprehensive cancer center in 2017. Brian Druker was named the director of the then OHSU Cancer Institute in 2007. Tom Sellers took over as director in 2024.

## Research areas

The Knight Cancer Institute employs over 200 investigators who are affiliated with one of four Cancer Research Programs: Cancer Biology, Cancer Prevention and Control, Quantitative Oncology, and Translational Oncology. The Cancer Biology program focuses on tumorigenesis, signal transduction, and the tumor microenvironment. It is led by researchers Mara Sherman and Melissa Wong. Susan Flocke and Kerri Winters-Stone lead the Cancer Prevention and Control research program, which explores cancer prevention and risk reduction, screening and early detection, and survivorship. The Quantitative Oncology program focuses on technology development, molecular characterization, and systems biology. The fourth research program, Translational Oncology, has themes of target validation and high-impact interventions. This program is led by Lara Davis and Jeffrey Tyner.
# Veys Rural District

Veys Rural District (Persian: دهستان ويس) is in Veys District of Bavi County, Khuzestan province, Iran. It is administered from the city of Veys.

## Demographics
### Population

At the time of the 2006 National Census, the rural district's population (as a part of the former Bavi District of Ahvaz County) was 23,322 in 3,916 households. There were 2,478 inhabitants in 586 households at the following census of 2011, by which time the district had been separated from the county in the establishment of Bavi County. The rural district was transferred to the new Veys District. The 2016 census measured the population of the rural district as 2,318 in 565 households. The most populous of its 22 villages was Robeykheh, with 613 people.
# Vinit Dhulap

Vinit Dhulap (born 6 December 1989) is an Indian cricketer. He made his first-class debut for Railways in the 2017–18 Ranji Trophy on 25 November 2017.
# List of The Wheel of Time (TV series) soundtracks

The Wheel of Time is an American high fantasy television series developed by Rafe Judkins for Amazon Prime Video, based on the book series of the same name by Robert Jordan and Brandon Sanderson. The music for the series is composed by Lorne Balfe. To date, four soundtrack albums have been released for the first season, and two albums for the second season.

## Season 1
### The First Turn

A soundtrack album for the series, The First Turn, was released a week before television premiere on November 12, 2021, by Milan Records in digital, CD, and vinyl formats. The album contains fourteen tracks that are largely conceptual but include key themes that spawned variations in the final score. Balfe said that "The score to this series is a re-imagination of fantasy music, doing away with the genre's reliance on large, traditional orchestras in favor of more modern colors while retaining the strong melodies and bold harmonies that fans can expect from such an epic."
All tracks are written by Lorne Balfe

### Volume 1

A second album, The Wheel of Time: Season 1, Volume 1, was released on November 19, 2021, featuring music that was largely used in the first season's first three episodes.
All tracks are written by Lorne Balfe

### Volume 2

The Wheel of Time: Season 1, Volume 2 was released on December 3, 2021.
All tracks are written by Lorne Balfe

### Volume 3

The final album, The Wheel of Time: Season 1, Volume 3, was released on December 17, 2021.
All tracks are written by Lorne Balfe

## Season 2

On January 12, 2022, Balfe confirmed that he would be returning to score the second season.

### Volume 1

The Wheel of Time: Season 2, Volume 1 was released on September 8, 2023.
All tracks are written by Lorne Balfe

### Volume 2

The Wheel of Time: Season 2, Volume 2 was released on September 22, 2023.
All tracks are written by Lorne Balfe

## Reception

James Southall of Movie Wave wrote "It is essential to approach The Wheel of Time with an open mind–it is far from what you would expect of the music for an epic fantasy, either in an historical sense or more modern examples. For me though it's really quite impressive what Lorne Balfe has conjured up–it's a sound that very much works in the context of the show and also one I've found has become quite compelling on these albums." Calling it as "intimidating and epic" Emma Ayars of Collider summarized "the soundtrack at times flattens the show's extensive lore. It serves its purpose in the series and the vocals are impressive, but it ranks lowest on the list for its lack of diversity in its musical choices."
# Wiffy Cox

Wilfred Hiram "Wiffy" Cox (October 27, 1896 – February 20, 1969) was an American professional golfer who played on the PGA Tour in the 1930s.

## Early life

Cox was born and grew up in a tough Irish-Italian section of Brooklyn, New York. He started in golf as a caddie at Westchester County courses and learned to play at sunrise and sunset with clubs borrowed from the pro shop. The diminutive Cox had a hot-temper and a reputation for foul-mouthed, trash talk among his fellow players.

## Professional career

Cox won nine times on the PGA Tour. His first individual win on the PGA Tour came at the 1931 North and South Open; his four wins that year led the PGA Tour for most wins. His best finish in a major championship was tied for third at the 1934 U.S. Open.
Cox played on the winning U.S. team in the 1931 Ryder Cup, winning both his matches.
Like most professional golfers of his generation, Cox earned his living primarily as a club pro. He was the course pro at Dyker Beach Golf Course in Brooklyn, New York from 1921 to 1935. He eventually landed a plum job as head pro at the Congressional Country Club in Bethesda, Maryland, which he held until 1969.

## Personal life

He died in Washington, D.C.

## Professional wins (12)
### PGA Tour wins (9)

* 1930 Mid-South Open Bestball (with Willie Macfarlane)
* 1931 Miami International Four-Ball (with Willie Macfarlane), North and South Open, Massachusetts Open, San Francisco National Match Play Open
* 1934 Agua Caliente Open, Texas Open
* 1936 Sacramento Open
* 1937 District Open
Source:

### Other wins (3)

* 1931 Florida Open (tie with Joe Turnesa)
* 1942 Maryland Open
* 1943 Long Island PGA Championship

## Results in major championships

| Tournament | 1923 | 1924 | 1925 | 1926 | 1927 | 1928 | 1929 | 1930 | 1931 | 1932 | 1933 | 1934 | 1935 | 1936 | 1937 | 1938 | 1939 |
| Masters Tournament | NYF | NYF | NYF | NYF | NYF | NYF | NYF | NYF | NYF | NYF | NYF | WD | T43 | T13 | 12 | T25 | |
| U.S. Open | | T29 | | | | | T11 | T35 | T4 | 5 | CUT | T3 | CUT | T5 | T45 | | CUT |
| PGA Championship | R64 | | | | | R32 | R32 | R32 | | | | | | | | R64 | |
Note: Cox never played in The Open Championship.
NYF = tournament not yet founded WD = withdrew CUT = missed the half-way cut R64, R32, R16, QF, SF = round in which player lost in PGA Championship match play "T" indicates a tie for a place
# Chepken

Chepken or chekmen (Tatar: чепкен / çepken "outerwear"; Karachay-Balkar: чепкен, romanized: çepken; Kumyk: чепген, romanized: çepgen; Russian: чекмень; Nogai: шепкен, romanized: şepken; Azerbaijani: çəpkən; Turkish: cepken) is a caftan worn among Turkic people and later by the Cossacks. It was also in wide use among Caucasians.

## Description

The clothing is in a transitional form between a robe and a fitting caftan without collar and most often made of cloth. The word "chepken" was used among Turkic groups in North Caucasus to refer to chokha and was often synonymous with that attire.
Among Azerbaijanis "chepken" is a type of lined upper shoulder clothing with long false sleeves. Chepkens were mainly sewn from cloth, velour or velvet as well as various silk brocade fabrics. It was worn mainly by women, but there is also a male version of this clothing. Depending on the age of the women, the colors of the chepkens varied. Young girls and women usually wore yellow, red or green, and older women wore white or black shirts. Chepkens were often sewn with cut linings that fit snugly to the body. In the lower side part of the clothes there was a detail called "chapyg" Azerbaijani: çapıq - "scar". They wore a chepken over a shirt, so it fitted well to the body. On the sides, the chepken had sleeves ending in armlets. Buttons were sometimes sewn to the sleeves.

## Etymology

The word "chepken" is of Turkic origin and has analogues in related Turkic languages, such as "chikman" and "chikpen" that translate to "chikmyan" in Tatar and Bashkir. In Turkmen "chepken" translates to 'cloth' and indicates the material from which this type of clothing was traditionally made. Kuban Cossacks called this kind of clothing "chekmen" and Circassians called it "shepken".

## Gallery

* Turkmen in chepken.
* Azerbaijani stamp depicting a couple wearing chepkens.
* Kyrgyz man in traditional attire which includes chepken.
# Kheyrabad, Arsanjan

Kheyrabad (Persian: خيراباد, also Romanized as Kheyrābād) is a village in Shurab Rural District, in the Central District of Arsanjan County, Fars province, Iran. At the 2006 census, its population was 169, in 33 families.
# Julien Grujon

Julien Grujon (7 May 1904 – 16 October 1976) was a French racing cyclist. He rode in the 1928 Tour de France.
# Brian Adams (basketball)

Brian Adams is an American basketball coach who is as an assistant coach for the Alabama Crimson Tide men's basketball team. He grew up in the state of New York.

## Coaching career
### College Coaching Career

Brian Adams was hired as coach for Harvard University and Marist College

### Agua Caliente Clippers

On August 1, 2018, Adams was named the head coach after previously serving as a player development coach with the Los Angeles Clippers.

### Philadelphia 76ers

On November 9, 2020, the Philadelphia 76ers hired Adams as a player development coach under Doc Rivers.

### Taipei Mars

On September 14, 2023, the Taipei Taishin Mars named Adams as their new head coach. On December 31, the Taipei Mars announced that Adams resigned from head coach.

### Detroit Pistons

On January 4, 2024, the Detroit Pistons named Adams as their new assistant coach. He was not kept by the team following the firing of Monty Williams.

### Alabama Crimson Tide

He was hired by Alabama as an assistant coach in July 2024.
# Harsawa

Harsawa is a village located in the Sikar district of Shekhawati region, in Rajasthan state, India. Harsawa is within the Fatehpur Tehsil, 8 km south along National Highway-11 from Fatehpur town. Sand dunes of the Thar Desert can be seen from Harsawa. As of 2001, the village had a total population of 1695.

## Geography

Harsawa is located at 27°55' North, 74°59' East. The total geographical area of the village is 4000 bigha (1,600 acres or 650 hectares). National Highway-11, from Bikaner to Jaipur, passes through Harsawa, as does the railway line from Bikaner to Jaipur. Harsawa is near to the historical village of Garinda.

## Demographics

As of the census of 2001, the population was 1695, of whom 829 were male and 866 were female. Literacy in the village is at 81.17%. All the villagers belong to the Hindu religion, and about ninety percent are of the Jat caste. castes include Rajputs, Brahmans, Swami, Harijans, Naik and Jangir. There is one temple of Hanumanji, one temple of the Goddess Mawali and one than (a sacred place) of Gogaji.
# Dinakdakan

Dinakdakan, also known as warekwarek, is a Filipino dish consisting of various pork head offal, red onions, siling haba or siling labuyo chilis, ginger, black peppercorns, calamansi juice, and bay leaves. The pork parts are first boiled in the aromatics for an hour or so until tender, and then further grilled until lightly charred. They are chopped into small pieces and served in a creamy sauce traditionally made from mashed cooked pig's brain, though this is commonly substituted with mayonnaise. The pork offal used commonly includes pork jowls (maskara), pork collar, and ears. Sometimes pork tongue, liver, stomach, and intestines are also included. Dinakdakan is most commonly served as pulutan, appetizers that are eaten with beer or other alcoholic drinks. It can also be eaten with rice.
Dinakdakan is very similar to the dish sisig from Kapampangan cuisine, however, dinakdakan is not as finely chopped and is always served with in a sauce made from mashed brain or mayonnaise.
# St. Francis Xavier X-Men and X-Women

The St. Francis Xavier X-Men and X-Women are the men's and women's athletic teams that represent St. Francis Xavier University in Antigonish, Nova Scotia, Canada. Their primary home turf is Oland Stadium located at the University's campus.

## History

In 1966, the X-Men Football team won the College Bowl (now the Vanier Cup) as top university football team in Canada. The X-Men Basketball program has won 3 CIS Championships (1993, 2000, and 2001) and in 2004, the X-Men Hockey team won their first CIS Championship. In 2011, the X-Women Hockey team placed 2nd at the CIS Championships in Ottawa and in 2016, the X-Men hockey team were runners-up in the CIS Championships in Halifax.
In 2006, the X-Women Rugby team became the first female StFX varsity team to win a CIS Championship, as 10-time defending AUS Rugby Champions. In 2008, the team placed 2nd at the CIS Championships in Lethbridge, Alberta after capturing their 12th consecutive AUS Championship. The team has a total of five National Championships, having won a fifth title in 2016 in Victoria, BC. and 17 consecutive conference championships from 1997 until 2014.
Between 2006 and 2016 the X-Men Cross Country team won 9 AUS Championships, including 6 consecutively and 2 CIS medals. In 2017 it was announced that alumnus, CIS Champion, and Olympian Eric Gillis would become head coach.

## Varsity teams

The X-Men & X-Women compete in:
* Basketball (m/w)
* Cross Country Running (m/w)
* Football (m)
* Ice Hockey (m/w)
* Rugby (w)
* Soccer (m/w)
* Track & Field (m/w)

## X-Men football

The X-Men football program has been in operation since 1954. They were the first Atlantic conference team to win a Vanier Cup national championship in 1966 and have also finished as runner-ups in the 1996 game. The team has won 16 Jewett Trophy conference championships.

## Women's ice hockey

The X-Women ice hockey team has participated in the Atlantic University Sport conference since the sport was established in the CIAU in 1997. The program has won 11 AUS conference championships with the most recent coming in 2020. Nationally, the program's best finish was in 2011 when they finished as national runners-up.
# Palatopharyngeus muscle

The palatopharyngeus (palatopharyngeal or pharyngopalatinus) muscle is a small muscle in the roof of the mouth.
It is a long, fleshy fasciculus, narrower in the middle than at either end, forming, with the mucous membrane covering its surface, the palatopharyngeal arch.

## Structure

It is separated from the palatoglossus muscle by an angular interval, in which the palatine tonsil is lodged. It arises from the soft palate, where it is divided into two fasciculi by the levator veli palatini and musculus uvulae.
* The posterior fasciculus lies in contact with the mucous membrane, and joins with that of the opposite muscle in the middle line.
* The anterior fasciculus, the thicker, lies in the soft palate between the levator and tensor veli palatini muscles, and joins in the middle line the corresponding part of the opposite muscle.
Passing laterally and downward behind the palatine tonsil, the palatopharyngeus joins the stylopharyngeus and is inserted with that muscle into the posterior border of the thyroid cartilage, some of its fibers being lost on the side of the pharynx and others passing across the middle line posteriorly to decussate with the muscle of the opposite side.

### Innervation

Motor innervation of this muscle is provided through the pharyngeal plexus of the CN X (vagal nerve), SVE (special visceral efferent) fibers.

## Function

The palatine velum is slightly raised by the levator veli palatini and made tense by the tensor veli palatini; the palatopharyngeus muscles, by their contraction, pull the pharynx upward over the bolus of food and nearly come together, the uvula filling up the slight interval between them.
By these means the bolus is prevented from passing into the nasopharynx; at the same time, the palatopharyngeus muscles form an inclined plane, directed obliquely downward and backward, along the under surface of which the bolus descends into the lower part of the pharynx.

## Additional images

* Cadaver dissection showing the palatopharyngeus muscle
# Jacopo

Jacopo (also Iacopo) is a masculine Italian given name, derivant from Latin Iacōbus. It is an Italian variant of Giacomo (James in English).
* Jacopo Aconcio (c. 1520 – c. 1566), Italian religious reformer
* Jacopo Bassano (c. 1510 – 1592), Italian painter
* Iacopo Barsotti (1921–1987), Italian mathematician
* Jacopo da Bologna (fl. 1340–1360), Italian composer
* Jacopo Robusti (1518–1594), Italian painter otherwise known as Tintoretto
* Jacopo Carucci (1494–1557), Italian painter otherwise known as Pontormo
* Jacopo Corsi (1561–1602), Italian composer
* Jacopo da Leona (died 1277), Italian poet
* Jacopo Peri (1561–1633), Italian composer
* Jacopo della Quercia (c. 1374 – 1438), Italian sculptor
* Jacopo Riccati (1676–1754), Italian mathematician
* Jacopo Sadoleto (1477–1547), Italian Catholic cardinal
Fictional characters:
* Jacopo, a key character in the 2002 film version of The Count of Monte Cristo (and a minor character in the book).
* Jacopo Bearzatti, one of the central characters of The House in Fata Morgana and the protagonist of the prequel The House in Fata Morgana: A Requiem for Innocence
* Jacopo Belbo, one of the main characters of Foucault's Pendulum by Umberto Eco
* Jacopo Peterman, a character portrayed by John O'Hurley in the sitcom Seinfeld
# GM 4T80 transmission

The 4T80E is a series of front wheel drive fully automatic transmissions from General Motors. Designed for transverse engine configurations, the series includes 4 gear bearing overdrive 2 electronic shift solenoids, and electronic force motor to control line pressure.
The 4Txx family is an evolution of the original Turbo-Hydramatic 125 transverse automatic introduced in the 1980 model year "X" body.
The 4T80-E transmission is electronically controlled and features an automatic overdrive transaxle with an electronically controlled torque converter clutch. The 4T80 originally used a viscous clutch, but this was changed in 2005 to ECCC.
The 4T80 is built at Willow Run Transmission in Ypsilanti, Michigan.

## 4T80-E

The "MH1" 4T80-E is able to handle vehicles up to 8000 lb (3628.74 kg) GVWR. The final drive ratio is 3.11:1, 3.48:1, or 3.71:1. The 4T80 uses a viscous torque converter clutch, which was replaced with EC3 (electronically controlled converter clutch) in 2005. Transmission broadcast codes in 2005 for the ECCC transmission are 5ABN and 5MMN.
The 4T80-E is a hydramatic transmission and was developed for use with V8 front-wheel-drive cars, and at the time exclusively the Cadillac Northstar engine. It was designed with extreme power handling capabilities at the time. The 4T80-E debuted in the Cadillac Allanté in 1993 along with the Northstar Double Overhead Camshaft (DOHC) V8. It reportedly cost 80% more than a similar GM 4T60 transmission and weighed 60 lb (27 kg) more.
This transaxle has been used in many of GM's front drive large sedans. The Cadillac Division had exclusive usage of the 4T80-E until the 1995 Oldsmobile Aurora debuted (may not be true) . The Aurora had the 4.0L version of the Northstar V8 coupled to a 4T80-E. It wasn't until 2004 that Pontiac got usage of this transaxle in the Bonneville GXP which employed a 275 horsepower version of the Northstar 4.6L V8.
The 4T80-E was last used in 2011 on the Cadillac DTS and the Buick Lucerne (when equipped with the 4.6L Northstar).
Gear ratios:
| 1 | 2 | 3 | 4 | R |
| 2.96 | 1.626 | 1.00 | 0.681 | 2.13 |
Applications:
* 3.11:1
** 1994–2005 Cadillac Deville
** 1993-2002 Cadillac Eldorado
** 1993-2004 Cadillac Seville
** 2006 Cadillac DTS
* 3.48:1
** 1995-1999 Oldsmobile Aurora
* 3.71:1
** 1996–2005 Cadillac Deville Concours/DTS
** 1993-2002 Cadillac Eldorado ETC
** 1993-2004 Cadillac Seville STS
** 1995-1999 Oldsmobile Aurora
** 2004–2005 Pontiac Bonneville GXP
** 2006-2011 Buick Lucerne V8
** 2001-2003 Oldsmobile Aurora V8